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Search of human proteins with 115529484
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
(1445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens] 2868 0.0
gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens] 2825 0.0
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens] 2542 0.0
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens] 522 e-147
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens] 513 e-145
gi|162809334 pregnancy-zone protein [Homo sapiens] 500 e-141
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens] 387 e-107
gi|169204289 PREDICTED: ovostatin [Homo sapiens] 382 e-105
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 329 1e-89
gi|178557739 complement component 4B preproprotein [Homo sapiens] 239 1e-62
gi|67190748 complement component 4A preproprotein [Homo sapiens] 239 2e-62
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s... 239 2e-62
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s... 235 3e-61
gi|115298678 complement component 3 precursor [Homo sapiens] 224 4e-58
gi|38016947 complement component 5 preproprotein [Homo sapiens] 183 9e-46
gi|169218213 PREDICTED: similar to complement component C3, part... 180 1e-44
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens] 177 5e-44
gi|239758130 PREDICTED: similar to complement component 4B (Chil... 117 6e-26
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 87 9e-17
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg... 72 3e-12
gi|239755748 PREDICTED: ovostatin [Homo sapiens] 57 1e-07
gi|169214179 PREDICTED: similar to complement component 3 [Homo ... 56 2e-07
gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 47 2e-04
gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 47 2e-04
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 35 0.68
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 35 0.68
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] 33 2.0
gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens] 33 2.6
gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sap... 33 2.6
gi|89264696 angiopoietin-like 4 protein isoform b precursor [Hom... 32 4.4
>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
Length = 1445
Score = 2868 bits (7434), Expect = 0.0
Identities = 1445/1445 (100%), Positives = 1445/1445 (100%)
Query: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA
Sbjct: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
Query: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST 120
ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST
Sbjct: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST 120
Query: 121 RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL 180
RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL
Sbjct: 121 RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL 180
Query: 181 SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS 240
SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS
Sbjct: 181 SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS 240
Query: 241 MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK 300
MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK
Sbjct: 241 MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK 300
Query: 301 NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL
Sbjct: 301 NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
Query: 361 KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY
Sbjct: 361 KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
Query: 421 TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG
Sbjct: 421 TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
Query: 481 SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG 540
SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG
Sbjct: 481 SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG 540
Query: 541 EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN 600
EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN
Sbjct: 541 EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN 600
Query: 601 ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY 660
ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY
Sbjct: 601 ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY 660
Query: 661 AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW 720
AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW
Sbjct: 661 AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW 720
Query: 721 VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV 780
VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV
Sbjct: 721 VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV 780
Query: 781 KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT 840
KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT
Sbjct: 781 KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT 840
Query: 841 ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI 900
ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI
Sbjct: 841 ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI 900
Query: 901 GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG 960
GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG
Sbjct: 901 GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG 960
Query: 961 YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH 1020
YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH
Sbjct: 961 YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH 1020
Query: 1021 QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS 1080
QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS
Sbjct: 1021 QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS 1080
Query: 1081 RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL 1140
RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL
Sbjct: 1081 RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL 1140
Query: 1141 DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT 1200
DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT
Sbjct: 1141 DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT 1200
Query: 1201 ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1260
ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV
Sbjct: 1201 ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1260
Query: 1261 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL 1320
YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL
Sbjct: 1261 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL 1320
Query: 1321 LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVS 1380
LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVS
Sbjct: 1321 LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVS 1380
Query: 1381 IVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYF 1440
IVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYF
Sbjct: 1381 IVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYF 1440
Query: 1441 MELWL 1445
MELWL
Sbjct: 1441 MELWL 1445
>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
Length = 1428
Score = 2825 bits (7322), Expect = 0.0
Identities = 1428/1445 (98%), Positives = 1428/1445 (98%), Gaps = 17/1445 (1%)
Query: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA
Sbjct: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
Query: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST 120
ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST
Sbjct: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST 120
Query: 121 RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL 180
RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL
Sbjct: 121 RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL 180
Query: 181 SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS 240
SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS
Sbjct: 181 SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS 240
Query: 241 MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK 300
MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK
Sbjct: 241 MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK 300
Query: 301 NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL
Sbjct: 301 NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
Query: 361 KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY
Sbjct: 361 KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
Query: 421 TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG
Sbjct: 421 TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
Query: 481 SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG 540
SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG
Sbjct: 481 SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG 540
Query: 541 EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN 600
EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN
Sbjct: 541 EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN 600
Query: 601 ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY 660
ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY
Sbjct: 601 ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY 660
Query: 661 AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW 720
AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW
Sbjct: 661 AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW 720
Query: 721 VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV 780
VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV
Sbjct: 721 VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV 780
Query: 781 KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT 840
KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT
Sbjct: 781 KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT 840
Query: 841 ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI 900
ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI
Sbjct: 841 ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI 900
Query: 901 GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG 960
GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG
Sbjct: 901 GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG 960
Query: 961 YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH 1020
YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH
Sbjct: 961 YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH 1020
Query: 1021 QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS 1080
QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS
Sbjct: 1021 QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS 1080
Query: 1081 RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL 1140
RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL
Sbjct: 1081 RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL 1140
Query: 1141 DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT 1200
DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT
Sbjct: 1141 DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT 1200
Query: 1201 ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1260
ERTNIQVTVTGPSSPSP LAVVQPTAVNISANGFGFAICQLNVV
Sbjct: 1201 ERTNIQVTVTGPSSPSP-----------------LAVVQPTAVNISANGFGFAICQLNVV 1243
Query: 1261 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL 1320
YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL
Sbjct: 1244 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL 1303
Query: 1321 LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVS 1380
LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVS
Sbjct: 1304 LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVS 1363
Query: 1381 IVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYF 1440
IVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYF
Sbjct: 1364 IVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYF 1423
Query: 1441 MELWL 1445
MELWL
Sbjct: 1424 MELWL 1428
>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
Length = 1368
Score = 2542 bits (6588), Expect = 0.0
Identities = 1277/1279 (99%), Positives = 1277/1279 (99%)
Query: 167 LIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL 226
L DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL
Sbjct: 90 LPSDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL 149
Query: 227 PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI 286
PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI
Sbjct: 150 PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI 209
Query: 287 NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ 346
NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ
Sbjct: 210 NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ 269
Query: 347 HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN 406
HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN
Sbjct: 270 HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN 329
Query: 407 SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT 466
SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT
Sbjct: 330 SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT 389
Query: 467 YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT 526
YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT
Sbjct: 390 YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT 449
Query: 527 PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI 586
PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI
Sbjct: 450 PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI 509
Query: 587 VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL 646
VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL
Sbjct: 510 VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL 569
Query: 647 TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY 706
TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY
Sbjct: 570 TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY 629
Query: 707 QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL 766
QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL
Sbjct: 630 QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL 689
Query: 767 EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH 826
EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH
Sbjct: 690 EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH 749
Query: 827 LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP 886
LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP
Sbjct: 750 LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP 809
Query: 887 NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT 946
NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT
Sbjct: 810 NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT 869
Query: 947 DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID 1006
DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID
Sbjct: 870 DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID 929
Query: 1007 QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI 1066
QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI
Sbjct: 930 QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI 989
Query: 1067 DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS 1126
DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS
Sbjct: 990 DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS 1049
Query: 1127 SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV 1186
SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV
Sbjct: 1050 SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV 1109
Query: 1187 ALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNIS 1246
ALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNIS
Sbjct: 1110 ALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNIS 1169
Query: 1247 ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS 1306
ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS
Sbjct: 1170 ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS 1229
Query: 1307 GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV 1366
GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV
Sbjct: 1230 GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV 1289
Query: 1367 RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH 1426
RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH
Sbjct: 1290 RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH 1349
Query: 1427 SSVIFIFCFKLLYFMELWL 1445
SSVIFIFCFKLLYFMELWL
Sbjct: 1350 SSVIFIFCFKLLYFMELWL 1368
Score = 184 bits (468), Expect = 4e-46
Identities = 93/94 (98%), Positives = 93/94 (98%)
Query: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA
Sbjct: 1 MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
Query: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLP 94
ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPS P
Sbjct: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSDP 94
>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
Length = 1454
Score = 522 bits (1344), Expect = e-147
Identities = 419/1501 (27%), Positives = 710/1501 (47%), Gaps = 184/1501 (12%)
Query: 20 LAVAPG-----PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVL 74
LA++P P +LVT P + + ++L P VK + + T +L
Sbjct: 10 LALSPAIAEELPNYLVTLPARLNFPSVQKVCLDL---SPGYSDVKFTVTLETKDKTQKLL 66
Query: 75 EAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQ 134
E G+ ++ L P +E+ +RV+G + I F ++ + + F+Q
Sbjct: 67 EYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSG-VGNNISFEEKKKVLIQRQGNGTFVQ 125
Query: 135 TDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGVISKTF 193
TDK LY P Q+V FRIVT+ S+F P +++ ++DP SN I QWL + G++ +F
Sbjct: 126 TDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLSF 185
Query: 194 QLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAK 253
QL+ +LG +++ V + + +F V EYVLPKF+V + P S + I +
Sbjct: 186 QLAPEAMLGTYTVAVA--EGKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKICCR 243
Query: 254 YTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYL 313
YTYGKP+ G V ++ +K T ++ + D + S +
Sbjct: 244 YTYGKPMLGAVQVSVC-------QKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPV 296
Query: 314 DLSS--------PGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLN 365
D+++ + I+ TV E TG+ N + N++ + F D + P+
Sbjct: 297 DMATFDLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFP 356
Query: 366 FTATVKVTRADGNQLTLEERRNNVVITV---TQRNYTEYWSGSNSGNQK--MEAVQKINY 420
F+ ++V D + L +N++V V T + + N+G +E
Sbjct: 357 FSGKIRVRGHDDSFL-----KNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGT 411
Query: 421 TVPQSGTFKIE--------FPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKT 472
V G F++E P ++ L L+ ++ ++S + +H L
Sbjct: 412 DVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRL------------- 458
Query: 473 RDENIKVGSPFELVV---------SGNKRLKELSYMVVSRGQLVAVGKQN---------- 513
+ +K G P E++V S ++ + SY ++ +G LV G+++
Sbjct: 459 -NGPLKCGQPQEVLVDYYIDPADASPDQEIS-FSYYLIGKGSLVMEGQKHLNSKKKGLKA 516
Query: 514 STMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEK 573
S SLT + P +++Y I G +++D ++ V++ F N++ L +S + P +
Sbjct: 517 SFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAE 576
Query: 574 VSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVV-----------HELELYNTGYY 622
V L++ P S+ + AVD+SV L+ +++ +V +++ Y+
Sbjct: 577 VELQLQAA-PGSLCALRAVDESVLLLRPDRELSNRSVYGMFPFWYGHYPYQVAEYDQCPV 635
Query: 623 LGMF-----------------------------MNSFAVFQECGLWVLTDANLTKDYIDG 653
G + + F+ F++ GL +L++A + K +D
Sbjct: 636 SGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEGTDLFSFFRDVGLKILSNAKIKKP-VDC 694
Query: 654 VYDNAEYAERFMEENEGHIVDIHDFS---LGSSPHVRKHFPETWIWLDTNMGYRIYQEFE 710
+ + EY+ M GH + VR++FPETW+W +G +
Sbjct: 695 SHRSPEYSTA-MGAGGGHPEAFESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVH 753
Query: 711 VTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITI 770
VTVPD+IT W A F S+ G GL+ T V L AF+PFF+ L LPYSV+RGE F L TI
Sbjct: 754 VTVPDAITEWKAMSFCTSQSRGFGLSPT-VGLTAFKPFFVDLTLPYSVVRGESFRLTATI 812
Query: 771 FNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEI 830
FNYLKD V+ + KS ++ + ++ Q + + +++ T + I LG I
Sbjct: 813 FNYLKDCIRVQTDLAKSHEYQLESWADS------QTSSCLCADEAKTHHWNITAVKLGHI 866
Query: 831 PITVTAL----------------SPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQ 874
T++ SD + + +LVK EG+ + S LL ++
Sbjct: 867 NFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKPVLVKPEGVLVEKTHSSLL-CPKGKVA 925
Query: 875 STLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIY 934
S +++S P + V S + +T +GD++G ++ L L++MP GCGEQNM+ FAP IY
Sbjct: 926 S--ESVSLELPVDIVPDSTKAYVTVLGDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIY 983
Query: 935 ILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLR 994
+L YL K LT+ ++ +A+ F+ GYQ+EL+Y+ +GS+SAFG D +G+TWL+AFV +
Sbjct: 984 VLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTK 1043
Query: 995 CFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVT 1054
CF +A +I ID + W+ G+Q +G + + G ++H+ ++GG V+LTAY+
Sbjct: 1044 CFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTA 1103
Query: 1055 SLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKE-ALNMLTW 1113
+LL K + V + + L++ + ++ YT AL+ Y S G + L L
Sbjct: 1104 ALLEMGKDVDDPMVSQGLRCLKNS-ATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQ 1162
Query: 1114 RAEQEGGMQFWVSSESKLSDS--W-QPRSLDIEVAAYALLSH-----FLQFQTSEGIPIM 1165
+A G +W + S++ W +P ++D+E+ AYALL+ Q + ++ I+
Sbjct: 1163 QAIISGESIYWSQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATSIV 1222
Query: 1166 RWLSRQRNSLGGFASTQDTTVALKALSEFA--ALMNTERTNIQVTVTGPSSPSPVKFLID 1223
WL++QRN+ GGF+STQDT VAL+AL+++A A M +E N+ V T + F I
Sbjct: 1223 AWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINLVVKSTENFQRT---FNIQ 1279
Query: 1224 THNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDL 1283
+ NRL+ Q L V P + A+G G Q + YN+ N + F L
Sbjct: 1280 SVNRLVFQQDTLPNV-PGMYTLEASGQGCVYVQTVLRYNILPP---------TNMKTFSL 1329
Query: 1284 DVAVK----ENKDDLNHVDLNVCTSFSGP-GRSGMALMEVNLLSGF--MVPSEAISLSE- 1335
V + E + L + TS+ G S MA++EV +LSGF M + + L +
Sbjct: 1330 SVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQP 1389
Query: 1336 TVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSY 1395
VKKVE+ LN+YLD + + ++ V+N + A++ + DYY P QA Y
Sbjct: 1390 LVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQY 1449
Query: 1396 N 1396
+
Sbjct: 1450 S 1450
>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
Length = 1474
Score = 513 bits (1321), Expect = e-145
Identities = 434/1508 (28%), Positives = 707/1508 (46%), Gaps = 179/1508 (11%)
Query: 12 LLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTV 71
LL + +V+ P+++V P ++ G LL + VTV A L N ++
Sbjct: 15 LLVLLPTDASVSGKPQYMVLVPSLLHTE-TTEKGCVLLSYLNETVTVSASLESVRGNRSL 73
Query: 72 SV-LEAEG-VFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRI 129
LEAE V +F +P N ++V G TQ+ F T + + +
Sbjct: 74 FTDLEAENDVLHCVAF---AVPKSSSNEEVMFLTVQVKGPTQE---FKKRTTVMVKNEDS 127
Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGV 188
VF+QTDK++YKP Q VKFR+V++ +F P + ++ I+DPK N I QW S Q + G+
Sbjct: 128 LVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGL 187
Query: 189 ISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPKFEVTLQTPLYCSMNSKHLN 247
+F LSS P G + + VQ + F V E+VLPKFEV + P ++ + +N
Sbjct: 188 KQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMN 247
Query: 248 GTITAKYTYGKPVKGDVTLT----FLPLSFWGKKKNITKTFKINGSANFS--FNDEEMKN 301
++ YTYGKPV G VT++ + S + + K +G N F +
Sbjct: 248 VSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTK 307
Query: 302 VMDSSNGLSEY-LDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
V EY + L + ++ TV E +TG + T K + F +
Sbjct: 308 VFQLKR--KEYEMKLHTEAQIQEEGTVVE-LTGRQSSEITRTITK-----LSFVKVDSHF 359
Query: 361 KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
+ + F V++ G + N VI + + N Y+S + + + IN
Sbjct: 360 RQGIPFFGQVRLVDGKGVPIP------NKVIFI-RGNEANYYSNATTDEHGLVQFS-INT 411
Query: 421 T--VPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SPSKTYIQLKTRDEN 476
T + S T ++ + Q ++ + A H+ + SPSK+++ L+
Sbjct: 412 TNVMGTSLTVRVNYKDRSPCYGYQ----WVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHE 467
Query: 477 IKVGSPFEL----VVSGNKRL--KELS--YMVVSRGQLVAVGKQNSTM----------FS 518
+ G + +++G L K+LS Y+++++G +V G + S
Sbjct: 468 LPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSIS 527
Query: 519 LTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRI 578
+ ++ P A +++Y + G++I D K V+ NK+ L +S ++ P+ LR+
Sbjct: 528 IPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRV 587
Query: 579 SVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLG-------------- 624
+ P S+ + AVD+SV LM +++ +V + L + + G
Sbjct: 588 TAA-PQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRH 646
Query: 625 -MFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNAE---------- 659
+++N ++ ++ GL T++ + K + E
Sbjct: 647 NVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVG 706
Query: 660 -YAERFMEENEGHIVDIHDFSLGSSPH---VRKHFPETWIWLDTNMGYRIYQEFEVTVPD 715
Y M +V + + PH VRK+FPETWIW + E VTVPD
Sbjct: 707 FYESDVMGRGHARLVHVEE------PHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPD 760
Query: 716 SITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLK 775
+IT W A F +SED GLG+++T L+AFQPFF+ L +PYSVIRGE F L+ T+ NYL
Sbjct: 761 TITEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLP 819
Query: 776 DATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVT 835
V V +E S F + E Q + + TV + + P LG + TV+
Sbjct: 820 KCIRVSVQLEASPAFLAVPVEKE------QAPHCICANGRQTVSWAVTPKSLGNVNFTVS 873
Query: 836 ALSPTAS----------------DAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKT 879
A + + D V + +LV+ EG+EK + + LL + + +
Sbjct: 874 AEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVS---EE 930
Query: 880 LSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYL 939
LS PPN V S R ++ +GD+LG ++ +L++MPYGCGEQNM+ FAPNIY+LDYL
Sbjct: 931 LSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYL 990
Query: 940 TKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY--DPSGSTWLSAFVLRCFL 997
+ +QLT +K KA+ ++ GYQR+L Y+ DGS+S FG G+TWL+AFVL+ F
Sbjct: 991 NETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFA 1050
Query: 998 EADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLL 1057
+A YI ID+ + + WL QK NG F G ++++ ++GG + VTL+AYI +LL
Sbjct: 1051 QARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALL 1110
Query: 1058 GYRKYQPNIDVQESIHFLESEFSRGI-----SDNYTLALITYALSSVGS-PKAKEALNML 1111
+ V+ ++ LES + S YT AL+ YA + G+ K KE L L
Sbjct: 1111 EIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSL 1170
Query: 1112 TWRAEQEGGMQFW---VSSESKLSDSWQPR--SLDIEVAAYALLSHFL--QFQTSEGIP- 1163
A ++ W ++ + ++P+ S ++E+ +Y LL++ TSE +
Sbjct: 1171 NEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTS 1230
Query: 1164 ---IMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPS-PVK 1219
I++W+++Q+N+ GGF+STQDT VAL ALS++ A T RT VT SS + K
Sbjct: 1231 ATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFT-RTGKAAQVTIQSSGTFSSK 1289
Query: 1220 FLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQE 1279
F +D +NRLLLQ L + P ++ G G Q ++ YN+ + +E
Sbjct: 1290 FQVDNNNRLLLQQVSLPEL-PGEYSMKVTGEGCVYLQTSLKYNI-----------LPEKE 1337
Query: 1280 AFDLDVAVKENKDDLN----HVDLNVCTSFSGPG---RSGMALMEVNLLSGFMVPSEAIS 1332
F + V+ + H + S S G S MA+++V ++SGF+ +
Sbjct: 1338 EFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVK 1397
Query: 1333 L---SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRR 1389
+ S V + E + +YLD V+ + +++ V + + A V + DYYE
Sbjct: 1398 MLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDE 1457
Query: 1390 QAVRSYNS 1397
A+ YN+
Sbjct: 1458 FAIAEYNA 1465
>gi|162809334 pregnancy-zone protein [Homo sapiens]
Length = 1482
Score = 500 bits (1287), Expect = e-141
Identities = 426/1504 (28%), Positives = 701/1504 (46%), Gaps = 168/1504 (11%)
Query: 12 LLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTV 71
LL + +A+ + + P+++V P ++ G LL H VTV A L N +
Sbjct: 14 LLILLSASDSNSTEPQYMVLVPSLLHTEAPKK-GCVLLSHLNETVTVSASLESGRENRS- 71
Query: 72 SVLEAEGVFEKGSFK--TLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRI 129
L + V EK F + TLP + +S +++ G TQD +T L T+ +
Sbjct: 72 --LFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQD--FRKRNTVLVLNTQSL 127
Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGV 188
VF+QTDK +YKP Q V+FR+V++ +F+P + ++ +++P+ N I QW S + + G+
Sbjct: 128 -VFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAGI 186
Query: 189 ISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPKFEVTLQTPLYCSMNSKHLN 247
+F LSS PI G + + VQ Q F V E+VLPKFEV +Q P S+ + +N
Sbjct: 187 NQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVN 246
Query: 248 GTITAKYTYGKPVKGDVTLTF---LPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMD 304
T+ +YTYGKPV G T++ L K+ + + F ++N + ++
Sbjct: 247 ITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQLNSNGCITQQVHTKMLQ 306
Query: 305 SSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSL 364
+N E + L + T E VT + TN+ K ++F + + +
Sbjct: 307 ITNTGFE-MKLRVEARIREEGTDLE-VTANRISEITNIVSK-----LKFVKVDSHFRQGI 359
Query: 365 NFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQ 424
F A V + DG + + + + + N Y+S + + Q + A IN T
Sbjct: 360 PFFAQVLLV--DGKGVPIPNKLFFISV-----NDANYYSNATTNEQGL-AQFSINTT--S 409
Query: 425 SGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SPSKTYIQLKTRDENIKVG-- 480
K+ + L ++ A H+ + S S +YI L+ + G
Sbjct: 410 ISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHT 469
Query: 481 ----SPFELVVSGNKRLKELS--YMVVSRGQLVAVGK----------QNSTMFSLTPENS 524
+ + L L ELS Y+++++G +V G + S S E+
Sbjct: 470 ETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESD 529
Query: 525 WTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPD 584
P A + ++ I DGE++ D K ++ NK+ L +S ++ P+ L+++ P
Sbjct: 530 VAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAA-PQ 588
Query: 585 SIVGIVAVDKSVNLMNASNDITMENVVHELE--------------------------LYN 618
S+ + AVD+SV LM ++++ +V + L ++N
Sbjct: 589 SLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHN 648
Query: 619 TGYYLGMFMNS---FAVFQECGLWVLTDANLTK--------DYIDGVYDNAEYAERFMEE 667
Y+ + N ++ + GL V T++ + K G Y
Sbjct: 649 GAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVV 708
Query: 668 NEGHIVDIHDFSL---------GSSPH-VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSI 717
++ + +++ G P VR +FPETWIW + E VTVPD+I
Sbjct: 709 ERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTI 768
Query: 718 TSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDA 777
T W A F +SED GLG+++T L+AFQPFF+ L +PYSVIRGE F L+ T+ NYL
Sbjct: 769 TEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKC 827
Query: 778 TEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTAL 837
V V ++ S F L + N T +++ + + T+ + + P LG + +V+A
Sbjct: 828 IRVSVQLKASPAF--LASQN----TKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAE 881
Query: 838 SPTA----------------SDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLS 881
+ + D V + +LV+AEGIE+ + S +T + + LS
Sbjct: 882 AMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTFS---SMTCASGANVSEQLS 938
Query: 882 FSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTK 941
P N V S R + +GD+LG ++ + +L++MPYGCGEQNM+ FAPNIY+L+YL +
Sbjct: 939 LKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNE 998
Query: 942 KKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY--DPSGSTWLSAFVLRCFLEA 999
+QLT +K KA+ ++ GYQR+L Y+ +DGS+S FG G+TWL+AFVL+ F +A
Sbjct: 999 TQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQA 1058
Query: 1000 DPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGY 1059
YI ID+ + ++ TWL QK NG F G ++++ ++GG + TL+AY+ +LL
Sbjct: 1059 RSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEI 1118
Query: 1060 RKYQPNIDVQESIHFLES------EFSRGISDNYTLALITYALSSVGSP-KAKEALNMLT 1112
N V+ ++ LES E + G S YT AL+ YA S +G + +E LN L
Sbjct: 1119 PLPVTNPIVRNALFCLESAWNVAKEGTHG-SHVYTKALLAYAFSLLGKQNQNREILNSLD 1177
Query: 1113 WRAEQEGGMQFWVSSESKLSD-----SWQPRSLDIEVAAYALLSHF------LQFQTSEG 1161
A +E + W + + Q S ++E+ +Y LL++ +
Sbjct: 1178 KEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSA 1237
Query: 1162 IPIMRWLSRQRNSLGGFASTQDTTVALKALSEF--AALMNTERTNIQVTVTGPSSPSPVK 1219
I++W+ +Q+N+ GGF+STQDT VAL ALS + A TE+T QVTV S
Sbjct: 1238 TNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKT-AQVTVQ-DSQTFSTN 1295
Query: 1220 FLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQE 1279
F +D +N LLLQ L + P I+ G Q ++ YN+ +
Sbjct: 1296 FQVDNNNLLLLQQISLPEL-PGEYVITVTGERCVYLQTSMKYNILPE---------KEDS 1345
Query: 1280 AFDLDVAVKENKDDLN--HVDLNVCTSFSGPGR---SGMALMEVNLLSGFMVPSEAISL- 1333
F L V D + H + + S G S M +++V ++SGF+ + +
Sbjct: 1346 PFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKML 1405
Query: 1334 --SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQA 1391
S +V + E + + +Y++ V + +++ V + + A V + DYYE
Sbjct: 1406 ERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESV 1465
Query: 1392 VRSY 1395
V Y
Sbjct: 1466 VAEY 1469
>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
Length = 1394
Score = 387 bits (993), Expect = e-107
Identities = 360/1344 (26%), Positives = 594/1344 (44%), Gaps = 184/1344 (13%)
Query: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS 190
VF+QTDK YKP Q+ I F D + T NI +KDP++N I QW + S +
Sbjct: 110 VFVQTDKPTYKPGQKDVNGIAQFFLDTYTF-TYPNITLKDPQNNRIFQWQNVTSFRNITQ 168
Query: 191 KTFQLSSHPILGDWSIQVQVNDQ-TYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGT 249
+FQL S P+ GD+ I V+ N + T F V YVLPKFEVT+ P +++
Sbjct: 169 LSFQLISEPMFGDYWIVVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVD 228
Query: 250 ITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEM--KNVMDSSN 307
+ AKYT+G+PV+G K I + S+N ND E+ + + N
Sbjct: 229 VCAKYTFGQPVQG--------------KTQIRVCREYFSSSNCEKNDNEICEQFIAQLEN 274
Query: 308 GL------SEYLDLSSPG---PVEILTTVTESVTG---ISRNVSTNVFFKQHDYIIEFFD 355
G ++ L G + VTE TG + + T+VF Q + F +
Sbjct: 275 GCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLLGTVNFEN 334
Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
T + +++ T+K + D N + + + + Q + + G+ + ++ EA
Sbjct: 335 MDTFYRRGISYFGTLKFS--DPNNVPMVNK-------LLQLELNDEFIGNYTTDENGEA- 384
Query: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGS---KSSMAVHSLF-KSPSKTYIQLK 471
+++ S F EF + ++ ++ K+ +L S + H L + S+T LK
Sbjct: 385 ---QFSIDTSDIFDPEFNL--KATYVRPKSCYLPSWLTPQYLDAHFLVSRFYSRTNSFLK 439
Query: 472 TRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQ---LVAVGKQNSTM------------ 516
E ++ + VV+ + L +Y S + LV++ +
Sbjct: 440 IVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRISSSPIYTA 499
Query: 517 ------FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEP 570
F L+ P A + VY + GEI++D ++ V FK+K+ + +S + P
Sbjct: 500 WNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLP 559
Query: 571 SEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITME---NVVHELELYNTGYY----- 622
SL + P + AVD +V L+ + ++ E N+V +E Y Y+
Sbjct: 560 GSNASLYLQAA-PVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLD 618
Query: 623 ----------LGMFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNA 658
MF N + + + GL V T+ + K + +
Sbjct: 619 DGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRL 678
Query: 659 EYAERFMEENEG----HIVDIHDFSLGSSPH---------VRKHFPETWIWLDTNMGYRI 705
+ E E H V G + VR +FPETW+W ++
Sbjct: 679 PLPKPLYLETENYGPMHSVPSRIACRGENADYVEQAIIQTVRTNFPETWMWDLVSVDSSG 738
Query: 706 YQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFA 765
+PD+IT W A+GF ++ D+G G+++T L+ QPFFI + P+SV++ E+F
Sbjct: 739 SANLSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVSQPFFIEIASPFSVVQNEQFD 797
Query: 766 LEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPT 825
L + F+YL E+ V +E+S ++ + + +IN + ++ + T ++ I P
Sbjct: 798 LIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSE-----VIQAGGRKTNIWTIIPK 852
Query: 826 HLGEIPITVTALSPTAS---------------DAVTQMILVKAEGIEKSYSQSILLDLTD 870
LG++ ITV A S +S D V + LV+ EGIEK +QS L+ T+
Sbjct: 853 KLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEKERTQSFLI-CTE 911
Query: 871 NRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFA 930
S L P + V GS R T +GD+LG ++ L +++MPYG GEQN A
Sbjct: 912 GAKASKQGVLDL--PNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGGGEQNAALLA 968
Query: 931 PNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSA 990
+ Y+LDYL +QLT+ ++ KA + GYQR+L ++ DGS+S F + GS WLSA
Sbjct: 969 SDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSA 1028
Query: 991 FVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTA 1050
+ ++ ID+NV +T WL QK++G F + G++ + +GG++ ++LTA
Sbjct: 1029 LTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTA 1088
Query: 1051 YIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEA-LN 1109
Y+V ++ ++ LE+ G+++ Y A++ YA + G K E+ L
Sbjct: 1089 YVVGMFFEAGLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQ 1148
Query: 1110 MLTWRAEQEGGMQFWVSSESKLSDS------WQPRSLDIEVAAYALLSHFLQFQTSEGIP 1163
L A + + +W ++ W P S E + Y LL+ S IP
Sbjct: 1149 TLDQSATKLNNVIYWERERKPKTEEFPSFIPWAP-SAQTEKSCYVLLA-----VISRKIP 1202
Query: 1164 -------IMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPS 1216
I++WL++Q NS GGF+S Q V L ++ + VT + S S
Sbjct: 1203 DLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSKNQNTVTFSSEGS-S 1261
Query: 1217 PVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNV----KASGSSRRR 1272
++F + HNRLL+Q +E+ P + G G Q + YNV KASG
Sbjct: 1262 EIQF--NGHNRLLVQRSEVTQA-PGQYTVDVEGRGCTFIQATLKYNVLLPKKASG----- 1313
Query: 1273 RSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSG-PGRSGMALMEVNLLSGFMVPSEAI 1331
F L + + +N L DL V ++G +S M +++V +LSGF +I
Sbjct: 1314 --------FSLSLEIVKNY-SLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSI 1364
Query: 1332 SLSETVKKVEYDHGKLNLYLDSVN 1355
+ + Y D +N
Sbjct: 1365 EEVNNRSLIFHHKDSYIEYKDKIN 1388
>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
Length = 1353
Score = 382 bits (980), Expect = e-105
Identities = 354/1311 (27%), Positives = 581/1311 (44%), Gaps = 189/1311 (14%)
Query: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS 190
VF+QTDK YKP Q+ I F D + T NI +KDP++N I Q + S +
Sbjct: 61 VFVQTDKPTYKPGQKDVNGIAQFFLDTYTF-TYPNITLKDPQNNRIFQRQNVTSFRNITQ 119
Query: 191 KTFQLSSHPILGDWSIQVQVND-QTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGT 249
+FQL S P+ GD+ I V+ N +T F V YVLPKFEVT+ P +++
Sbjct: 120 LSFQLISEPMFGDYWIVVKRNSRETVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVD 179
Query: 250 ITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEM--KNVMDSSN 307
+ AKY +G+PV+G+ + F S+N N+ E+ + + N
Sbjct: 180 VCAKYNFGQPVQGETQIRVCREYF--------------SSSNCEKNENEICEQFIAQLEN 225
Query: 308 GL------SEYLDLSSPG---PVEILTTVTESVTG---ISRNVSTNVFFKQHDYIIEFFD 355
G ++ L G + VTES TG + + T+VF Q + F +
Sbjct: 226 GCVSQIVNTKVFQLYRSGLFMTFHVAVIVTESGTGNYFMQISEKTSVFITQLLGTVNFEN 285
Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
T + +++ T+K + D N + + + + Q + + G+ + ++ EA
Sbjct: 286 MDTFYRRGISYFGTLKFS--DPNNVPMVNK-------LLQLELNDEFIGNYTTDENGEA- 335
Query: 416 QKINYTVPQSGTFKIEFP-----ILEDSSELQ-------LKAYFLGSKSSMAVHSLFKS- 462
+++ S F EF + +S L L A+FL S+ +S K
Sbjct: 336 ---QFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIV 392
Query: 463 PSKTYIQLKTR----------------DENIKVGSPFELVVSGNKRLKELSYMVVSRGQL 506
P ++ + D N+K F +VS + + + S
Sbjct: 393 PEPKQLECNQQKVVTVHYSLNSEAYEDDSNVK----FFYLVSLSHDSGNFQHRISSSPIY 448
Query: 507 VAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKV 566
A S S++ + + P A + VY + GEI++D ++ V FK+K+ + +S
Sbjct: 449 TAWNGNFSFPISISADLA--PAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNE 506
Query: 567 KAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITME---NVVHELELYNTGYY- 622
+ P SL + P + AVD++V L+ + ++ E N+V +E Y Y+
Sbjct: 507 QGLPGSNASLCLQAA-PVLFCALRAVDRNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHG 565
Query: 623 --------------LGMFMNS--------------FAVFQECGLWVLTDANLTKDYIDGV 654
MF N + + + GL V T+ + K + +
Sbjct: 566 LNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVM 625
Query: 655 YDNAEYAERFMEENE---------------GHIVDIHDFSLGSSPHVRKHFPETWIWLDT 699
+ E E G D + ++ + VR +FPETW+W
Sbjct: 626 ERRLPLPKPLYLETENYGPMRSVPSRIACRGENADYVEQAIIQT--VRTNFPETWMWDLV 683
Query: 700 NMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVI 759
++ +PD+IT W A+GF ++ D+G G+++T L+ QPFFI + P+SV+
Sbjct: 684 SVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVSQPFFIEIASPFSVV 742
Query: 760 RGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVL 819
+ E+F L + +F+Y E+ V +E+S ++ + + +IN + ++ + T +
Sbjct: 743 QNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANIHTLKINGSE-----VIQAGGRKTNV 797
Query: 820 FPIRPTHLGEIPITVTALSPTAS---------------DAVTQMILVKAEGIEKSYSQSI 864
+ I P LG++ ITV A S +S D V Q LV+ EGIEK +QS
Sbjct: 798 WTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVQSFLVEPEGIEKERTQSF 857
Query: 865 LLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQ 924
L+ T+ S L P + V GS R T +GD+LG ++ L +++MPYG GEQ
Sbjct: 858 LI-CTEGAKASKQGVLDL--PNDVVEGSARGFFTVVGDILGLALQNLV-VLQMPYGSGEQ 913
Query: 925 NMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSG 984
N A + Y+LDYL +QLT+ ++ KA + GYQR+L ++ DGS+S F G
Sbjct: 914 NAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQSQKG 973
Query: 985 STWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKS 1044
S LSA + Y+ ID+NV +T WL QK++G F + G++ + +GG++
Sbjct: 974 SIXLSALTFKTLERMKKYVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEE 1033
Query: 1045 PVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKA 1104
++LTAY+V ++ ++ LE+ G+++ Y A++ YA + G K
Sbjct: 1034 DISLTAYVVGMFFEAGLNFTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQ 1093
Query: 1105 KEA-LNMLTWRAEQEGGMQFWVSSESKLSDS------WQPRSLDIEVAAYALLSHFLQFQ 1157
E+ L L A + + +W ++ W P S E + Y LL+
Sbjct: 1094 VESLLQTLDQSAPKLNNVIYWERERKPKTEEFPSFIPWAP-SAQTEKSCYVLLA-----V 1147
Query: 1158 TSEGIP-------IMRWLSRQRNSLGGFASTQDTTVA--LKALSEFAALMNTER---TNI 1205
S IP I++WL+++ NS GGF+S Q V L A+ L E +
Sbjct: 1148 ISRKIPDLTYASKIVQWLAQRMNSHGGFSSNQVINVGLILIAICLMQKLARGEEGLFSKD 1207
Query: 1206 QVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNV-- 1263
Q TVT S S F ++ HNRLL+Q +E+ P + G G Q + YNV
Sbjct: 1208 QNTVTFSSEGSSEIFQVNGHNRLLVQRSEVTQA-PGEYTVDVEGHGCTFIQATLKYNVLL 1266
Query: 1264 --KASGSSRRRRSIQN--QEAFDLDVAVK----ENKDDLNHVDLNVCTSFS 1306
KASG S ++N AFDL V +K NK + +D+ + + F+
Sbjct: 1267 PKKASGFSLSLEIVKNYSSTAFDLTVTLKYTGIRNKSSMVVIDVKMLSGFT 1317
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
8 [Homo sapiens]
Length = 1932
Score = 329 bits (844), Expect = 1e-89
Identities = 209/567 (36%), Positives = 310/567 (54%), Gaps = 47/567 (8%)
Query: 874 QSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNI 933
+S + + P + GSER + IGDV+GP++N L +L+R+P+GCGEQNMI+FAPN+
Sbjct: 1144 ESYSEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGEQNMIHFAPNV 1203
Query: 934 YILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVL 993
++L YL K +QL+ ++ + ++ QGYQR+L Y+R+DGS+SAFG D SGS WL+AFVL
Sbjct: 1204 FVLKYLQKTQQLSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDASGSMWLTAFVL 1263
Query: 994 RCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIV 1053
+ F +A +I +D L +W+ Q+++G F GRV++ ++QGG V LTAY+V
Sbjct: 1264 KSFAQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHGTVPLTAYVV 1323
Query: 1054 TSLL--GYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNML 1111
+LL G + ++ HFLES + D Y+ AL TYAL+ + SP A EAL L
Sbjct: 1324 VALLETGTASEEERGSTDKARHFLESAAPLAM-DPYSCALTTYALTLLRSPAAPEALRKL 1382
Query: 1112 TWRAEQEGGMQFWVSSES---------KLSD--SWQPRSLDIEVAAYALLSHFLQFQTSE 1160
A G+ W S S SD S S ++E+ AYALL++ L +
Sbjct: 1383 RSLAIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVEMTAYALLTYTLLGDVAA 1442
Query: 1161 GIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKF 1220
+P+++WLS+QRN+LGGF+STQDT VAL+AL+E+A L N+ V++ + F
Sbjct: 1443 ALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYAGGINLTVSLASTNLDYQETF 1502
Query: 1221 LIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVK---ASGSSRRRRSIQN 1277
+ N+ +LQTA + + PT + +SA G G + Q++V YNV A + + S+Q
Sbjct: 1503 ELHRTNQKVLQTAAIPSL-PTGLFVSAKGDGCCLMQIDVTYNVPDPVAKPAFQLLVSLQE 1561
Query: 1278 QE----------------------AFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMAL 1315
E A D D A ++ + V L VCT + G S MA+
Sbjct: 1562 PEAQGRPPPMPASAAEGSRGDWPPADDDDPAADQHHQEYK-VMLEVCTRWLHAGSSNMAV 1620
Query: 1316 MEVNLLSGFMVPSEA-----ISLSETVKKVEYDHGKLNLYLDSV-NETQFCVNIPAVRNF 1369
+EV LLSGF E+ + +K+ E ++ Y D + + CV A+R
Sbjct: 1621 LEVPLLSGFRADIESLEQLLLDKHMGMKRYEVAGRRVLFYFDEIPSRCLTCVRFRALREC 1680
Query: 1370 KVSNTQDASVSIVDYYEPRRQAVRSYN 1396
V T VS+ DYYEP +A R YN
Sbjct: 1681 VVGRTSALPVSVYDYYEPAFEATRFYN 1707
Score = 244 bits (624), Expect = 3e-64
Identities = 253/967 (26%), Positives = 412/967 (42%), Gaps = 170/967 (17%)
Query: 18 AALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAE 77
AA APG +L+ AP + R G I V + + P +VTV+A+L+ V++++
Sbjct: 72 AAQPQAPG--YLIAAPSVFRAGVEEVISVTIF-NSPREVTVQAQLVAQGE----PVVQSQ 124
Query: 78 G-VFEKGSFKTLTLPSLPLNSADEIYELRVTGR---TQDEILFSNSTRLSFETKRISVFI 133
G + +KG+ K L +P+ A L+V GR ++ LF N T ++ + + SVFI
Sbjct: 125 GAILDKGTIK-LKVPTGLRGQA----LLKVWGRGWQAEEGPLFHNQTSVTVDGRGASVFI 179
Query: 134 QTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDL-GVISKT 192
QTDK +Y+P+ V I T+ + +P L I DP+ + + +W + G+ + +
Sbjct: 180 QTDKPVYRPQHRVLISIFTVSPNLRPVNEKLEAYILDPRGSRMIEWRHLKPFCCGITNMS 239
Query: 193 FQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITA 252
F LS P+LG+W I V++ Y +SF+V +YVLPKFE+ + P Y GT+ A
Sbjct: 240 FPLSDQPVLGEWFIFVEMQGHAYNKSFEVQKYVLPKFELLIDPPRYIQDLDACETGTVRA 299
Query: 253 KYTYGKPVKGD--VTLTFLPLSFWGKK--KNITKTFKINGSANFSFNDEEMKNVMDSSNG 308
+YT+GKPV G + +T + ++ + + + +T KI GS +F +M
Sbjct: 300 RYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLRTTKILGSRDFDICVRDM--------- 350
Query: 309 LSEYLDLSSPGPVEILTTVTESVTG---ISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLN 365
+ + G V I VT SV G ++ + ST V + D I D KP L
Sbjct: 351 IPADVPEHFRGRVSIWAMVT-SVDGSQQVAFDDSTPVQRQLVD-IRYSKDTRKQFKPGLA 408
Query: 366 FTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQS 425
+ V+++ DG+ + +T YT + V Q
Sbjct: 409 YVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYT-------------------SEVVSQR 449
Query: 426 GTFKIEFPILEDSSE---LQLKAYFLGSK--------SSMAVHSLFKSPSKTYIQLKTRD 474
G E P + S++ L+ K L K S +++ S + SPS+ Y+QL+
Sbjct: 450 GLVGFEIPSIPTSAQHVWLETKVMALNGKPVGAQYLPSYLSLGSWY-SPSQCYLQLQPPS 508
Query: 475 ENIKVGSPFELVVSGNKRLK-ELSYMVVSRGQLVAVGKQNS------------------- 514
++VG V L Y V +RG +V G+Q +
Sbjct: 509 HPLQVGEEAYFSVKSTCPCNFTLYYEVAARGNIVLSGQQPAHTTQQRSKRAAPALEKPIR 568
Query: 515 ---------------------TMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQL 553
T L S P ++V+Y+ ++GE ++D L+ V+
Sbjct: 569 LTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEGVADSLQFAVET 628
Query: 554 VFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHE 613
F+N++ + +S + +P E V LRI + S V + AVDKSV L+ + +T V E
Sbjct: 629 FFENQVSVTYSANETQPGEVVDLRIRAAR-GSCVCVAAVDKSVYLLRSGFRLTPAQVFQE 687
Query: 614 LELYNTG-----------------------------YYLGMFMNSFAVFQECGLWVLTDA 644
LE Y+ + G+ +S F E GL V+TD
Sbjct: 688 LEDYDVSDSFGVSREDGPFWWAGLTAQRRRRSSVFPWPWGITKDSGFAFTETGLVVMTDR 747
Query: 645 NLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKH--FPETWIWLDTNMG 702
DG E F + + G +V + RK FPETWIW N+
Sbjct: 748 VSLNHRQDGGLYTDEAVPAF-QPHTGSLVAVAPSRHPPRTEKRKRTFFPETWIWHCLNIS 806
Query: 703 YRIYQ-EFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRG 761
+ V VPDSITSWV +S GLG+ P L+ F+PFF+ LP +IRG
Sbjct: 807 DPSGEGTLSVKVPDSITSWVGEAVALSTSQGLGI-AEPSLLKTFKPFFVDFMLPALIIRG 865
Query: 762 EEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFP 821
E+ + ++++NY+ EV + + + + + T + + V + +
Sbjct: 866 EQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFVGHPGKRHVT---KKMCVAPGEAEPIWVV 922
Query: 822 IRPTHLGEIPITVTALS-------------------------PTASDAVTQMILVKAEGI 856
+ + LG IT AL+ P D V + ++V+AEG+
Sbjct: 923 LSFSDLGLNNITAKALAYGDTNCCRDGRSSKHPEENHADRRVPIGVDHVRRSVMVEAEGV 982
Query: 857 EKSYSQS 863
++Y+ S
Sbjct: 983 PRAYTYS 989
>gi|178557739 complement component 4B preproprotein [Homo sapiens]
Length = 1744
Score = 239 bits (610), Expect = 1e-62
Identities = 235/838 (28%), Positives = 359/838 (42%), Gaps = 123/838 (14%)
Query: 686 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
VR FPE W+W + +Q + +PDS+T+W G +S+ GL TPV+L+ F
Sbjct: 774 VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
Query: 746 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805
+ F + L LP SV R E+ L ++NYL V V + + + G
Sbjct: 831 REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
Query: 806 QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862
Q +LVP+ V F + PT + + V A DAV++++ ++ EG + +
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAATAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
Query: 863 SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911
++ +L N L +TL + PN + + V++TA D LG S G+
Sbjct: 943 ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
Query: 912 ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968
ASL+R+P GCGEQ MI AP + YL K +Q L K+ A+ +++GY R ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
Query: 969 REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028
+ DGS++A+ STWL+AFVL+ A + L T WL Q+++G F
Sbjct: 1061 KADGSYAAW--LSRGSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
Query: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074
D VIH +QG GN V LTA++ +L K + + ++ F
Sbjct: 1119 DLSPVIHRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKASSF 1178
Query: 1075 LESEFSRGISDNYTLALITYALSSVGSPKAKE--ALNMLTWRAEQEGGMQFWVSSESKLS 1132
L + S G+ + A+ YAL+ +P A N L A++ G +W S S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
Query: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177
++ P +L IE AYALL L +E WL+RQ + GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298
Query: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1235
F STQDT +AL ALS + A TE + VT++ + +NR + EL
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
Query: 1236 AVVQPTAVNISANGFGFAICQLNVVYNV-KASGSSRRRRSIQ-------------NQEAF 1281
+ +N+ G ++ YNV ++ + I+ N++
Sbjct: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYE 1418
Query: 1282 DLDVAVKENKDD--------------------------------LNHVDLNVCTSFSGP- 1308
D + KDD + V VC +G
Sbjct: 1419 DYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKV 1478
Query: 1309 GRSGMALMEVNLLSGFMV----PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNI 1363
G SGMA+ +V LLSGF + SLS+ V E + + LY DSV ++ CV
Sbjct: 1479 GLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGF 1538
Query: 1364 PAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1415
AV+ V Q AS ++ DYY P R+ Y + K L S ++C +G P
Sbjct: 1539 EAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 1596
Score = 103 bits (257), Expect = 1e-21
Identities = 147/656 (22%), Positives = 271/656 (41%), Gaps = 67/656 (10%)
Query: 26 PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83
PR L+ +P ++ G +++GV+L + QV + L+ S N+ S + +
Sbjct: 21 PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80
Query: 84 SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129
F L+L +PL A E+ + + +D + + + + L F ++R
Sbjct: 81 DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139
Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189
+F+QTD+ +Y P Q V++R+ L +P ++ +++++ +++ +
Sbjct: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198
Query: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244
F + G W I + +D S F+V +YVLP FEV + TP Y
Sbjct: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257
Query: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297
HL+ I A+Y YGKPV+G + F L GKK ++T +NG ++ S +
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
Query: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355
E ++ ++ N G+++ L + + + ES G T+ +F + ++
Sbjct: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSK 373
Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
L P F V G+ + + + V S + S + V
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418
Query: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473
Q I SG I I + SELQL ++A ++ PS ++ ++
Sbjct: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERP 478
Query: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526
D +VG L V YM++SRGQ+V + K+ T S+ ++
Sbjct: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538
Query: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584
P + +Y D +++ L++ VQ + K++L K E V L + T
Sbjct: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596
Query: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
++V + A+D ++ + + + M V + Y+ G G ++ VFQ GL
Sbjct: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
>gi|67190748 complement component 4A preproprotein [Homo sapiens]
Length = 1744
Score = 239 bits (609), Expect = 2e-62
Identities = 235/838 (28%), Positives = 361/838 (43%), Gaps = 123/838 (14%)
Query: 686 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
VR FPE W+W + +Q + +PDS+T+W G +S+ GL TPV+L+ F
Sbjct: 774 VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
Query: 746 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805
+ F + L LP SV R E+ L ++NYL V V + + + G
Sbjct: 831 REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
Query: 806 QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862
Q +LVP+ V F + PT + + V A DAV++++ ++ EG + +
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
Query: 863 SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911
++ +L N L +TL + PN + + V++TA D LG S G+
Sbjct: 943 ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
Query: 912 ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968
ASL+R+P GCGEQ MI AP + YL K +Q L K+ A+ +++GY R ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
Query: 969 REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028
+ DGS++A+ + D STWL+AFVL+ A + L T WL Q+++G F
Sbjct: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
Query: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074
DP V+ +QG GN V LTA++ +L K + + ++ F
Sbjct: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178
Query: 1075 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1132
L + S G+ + A+ YAL+ +P A N L A++ G +W S S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
Query: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177
++ P +L IE AYALL L +E WL+RQ + GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQASAWLTRQGSFQGG 1298
Query: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1235
F STQDT +AL ALS + A TE + VT++ + +NR + EL
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
Query: 1236 AVVQPTAVNISANGFGFAICQLNVVYNV-KASGSSRRRRSIQ-------------NQEAF 1281
+ +N+ G ++ YNV ++ + I+ N++
Sbjct: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYE 1418
Query: 1282 DLDVAVKENKDD--------------------------------LNHVDLNVCTSFSGP- 1308
D + KDD + V VC +G
Sbjct: 1419 DYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKV 1478
Query: 1309 GRSGMALMEVNLLSGFMV----PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNI 1363
G SGMA+ +V LLSGF + SLS+ V E + + LY DSV ++ CV
Sbjct: 1479 GLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGF 1538
Query: 1364 PAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1415
AV+ V Q AS ++ DYY P R+ Y + K L S ++C +G P
Sbjct: 1539 EAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 1596
Score = 103 bits (257), Expect = 1e-21
Identities = 147/656 (22%), Positives = 271/656 (41%), Gaps = 67/656 (10%)
Query: 26 PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83
PR L+ +P ++ G +++GV+L + QV + L+ S N+ S + +
Sbjct: 21 PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80
Query: 84 SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129
F L+L +PL A E+ + + +D + + + + L F ++R
Sbjct: 81 DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139
Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189
+F+QTD+ +Y P Q V++R+ L +P ++ +++++ +++ +
Sbjct: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198
Query: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244
F + G W I + +D S F+V +YVLP FEV + TP Y
Sbjct: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257
Query: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297
HL+ I A+Y YGKPV+G + F L GKK ++T +NG ++ S +
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
Query: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355
E ++ ++ N G+++ L + + + ES G T+ +F + ++
Sbjct: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSK 373
Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
L P F V G+ + + + V S + S + V
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418
Query: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473
Q I SG I I + SELQL ++A ++ PS ++ ++
Sbjct: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERP 478
Query: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526
D +VG L V YM++SRGQ+V + K+ T S+ ++
Sbjct: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538
Query: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584
P + +Y D +++ L++ VQ + K++L K E V L + T
Sbjct: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596
Query: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
++V + A+D ++ + + + M V + Y+ G G ++ VFQ GL
Sbjct: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
sapiens]
Length = 1744
Score = 239 bits (609), Expect = 2e-62
Identities = 235/838 (28%), Positives = 361/838 (43%), Gaps = 123/838 (14%)
Query: 686 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
VR FPE W+W + +Q + +PDS+T+W G +S+ GL TPV+L+ F
Sbjct: 774 VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
Query: 746 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805
+ F + L LP SV R E+ L ++NYL V V + + + G
Sbjct: 831 REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
Query: 806 QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862
Q +LVP+ V F + PT + + V A DAV++++ ++ EG + +
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
Query: 863 SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911
++ +L N L +TL + PN + + V++TA D LG S G+
Sbjct: 943 ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
Query: 912 ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968
ASL+R+P GCGEQ MI AP + YL K +Q L K+ A+ +++GY R ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
Query: 969 REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028
+ DGS++A+ + D STWL+AFVL+ A + L T WL Q+++G F
Sbjct: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
Query: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074
DP V+ +QG GN V LTA++ +L K + + ++ F
Sbjct: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178
Query: 1075 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1132
L + S G+ + A+ YAL+ +P A N L A++ G +W S S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
Query: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177
++ P +L IE AYALL L +E WL+RQ + GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298
Query: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1235
F STQDT +AL ALS + A TE + VT++ + +NR + EL
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
Query: 1236 AVVQPTAVNISANGFGFAICQLNVVYNV-KASGSSRRRRSIQ-------------NQEAF 1281
+ +N+ G ++ YNV ++ + I+ N++
Sbjct: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYE 1418
Query: 1282 DLDVAVKENKDD--------------------------------LNHVDLNVCTSFSGP- 1308
D + KDD + V VC +G
Sbjct: 1419 DYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKV 1478
Query: 1309 GRSGMALMEVNLLSGFMV----PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNI 1363
G SGMA+ +V LLSGF + SLS+ V E + + LY DSV ++ CV
Sbjct: 1479 GLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGF 1538
Query: 1364 PAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1415
AV+ V Q AS ++ DYY P R+ Y + K L S ++C +G P
Sbjct: 1539 EAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 1596
Score = 100 bits (250), Expect = 8e-21
Identities = 146/656 (22%), Positives = 270/656 (41%), Gaps = 67/656 (10%)
Query: 26 PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83
PR L+ +P ++ G +++GV+L + QV + L+ S N+ S + +
Sbjct: 21 PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80
Query: 84 SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129
F L+L +PL A E+ + + +D + + + + L F ++R
Sbjct: 81 DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139
Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189
+F+QTD+ +Y P Q V++R+ L +P ++ +++++ +++ +
Sbjct: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198
Query: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244
F + G W I + +D S F+V +YVLP FEV + TP Y
Sbjct: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257
Query: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297
HL+ I A+Y YGKPV+G + F L GKK ++T +NG ++ S +
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
Query: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355
E ++ ++ N G+++ L + + + E G T+ +F + ++
Sbjct: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSK 373
Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
L P F V G+ + + + V S + S + V
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418
Query: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473
Q I SG I I + SELQL ++A ++ PS ++ ++
Sbjct: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWP 478
Query: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526
D +VG L V YM++SRGQ+V + K+ T S+ ++
Sbjct: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538
Query: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584
P + +Y D +++ L++ VQ + K++L K E V L + T
Sbjct: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596
Query: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
++V + A+D ++ + + + M V + Y+ G G ++ VFQ GL
Sbjct: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
sapiens]
Length = 1698
Score = 235 bits (599), Expect = 3e-61
Identities = 223/801 (27%), Positives = 347/801 (43%), Gaps = 95/801 (11%)
Query: 686 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
VR FPE W+W + +Q + +PDS+T+W G +S+ GL TPV+L+ F
Sbjct: 774 VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830
Query: 746 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805
+ F + L LP SV R E+ L ++NYL V V + + + G
Sbjct: 831 REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884
Query: 806 QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862
Q +LVP+ V F + PT + + V A DAV++++ ++ EG + +
Sbjct: 885 QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942
Query: 863 SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911
++ +L N L +TL + PN + + V++TA D LG S G+
Sbjct: 943 ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000
Query: 912 ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968
ASL+R+P GCGEQ MI AP + YL K +Q L K+ A+ +++GY R ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060
Query: 969 REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028
+ DGS++A+ + D STWL+AFVL+ A + L T WL Q+++G F
Sbjct: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118
Query: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074
DP V+ +QG GN V LTA++ +L K + + ++ F
Sbjct: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178
Query: 1075 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1132
L + S G+ + A+ YAL+ +P A N L A++ G +W S S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238
Query: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177
++ P +L IE AYALL L +E WL+RQ + GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298
Query: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAEL 1235
F STQDT +AL ALS + A TE + VT++ + +NR + EL
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEEL 1358
Query: 1236 AVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV-------- 1287
+ +N+ G ++ YNV ++N DL + V
Sbjct: 1359 QFSLGSKINVKVGGNSKGTLKVLRTYNV---------LDMKNTTCQDLQIEVTVKGHVEY 1409
Query: 1288 -KENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSG-----FMVPSEAISLSET-VKKV 1340
E +D + + + P + + L G + SLS+ V
Sbjct: 1410 TMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKLTSLSDRYVSHF 1469
Query: 1341 EYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK 1400
E + + LY DSV ++ CV AV+ V Q AS ++ DYY P R+ Y + K
Sbjct: 1470 ETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSK 1529
Query: 1401 ------LSSCDLCSDVQGCRP 1415
L S ++C +G P
Sbjct: 1530 SRLLATLCSAEVCQCAEGKCP 1550
Score = 100 bits (250), Expect = 8e-21
Identities = 146/656 (22%), Positives = 270/656 (41%), Gaps = 67/656 (10%)
Query: 26 PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83
PR L+ +P ++ G +++GV+L + QV + L+ S N+ S + +
Sbjct: 21 PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80
Query: 84 SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129
F L+L +PL A E+ + + +D + + + + L F ++R
Sbjct: 81 DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139
Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189
+F+QTD+ +Y P Q V++R+ L +P ++ +++++ +++ +
Sbjct: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198
Query: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244
F + G W I + +D S F+V +YVLP FEV + TP Y
Sbjct: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257
Query: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297
HL+ I A+Y YGKPV+G + F L GKK ++T +NG ++ S +
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317
Query: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355
E ++ ++ N G+++ L + + + E G T+ +F + ++
Sbjct: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSK 373
Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
L P F V G+ + + + V S + S + V
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418
Query: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473
Q I SG I I + SELQL ++A ++ PS ++ ++
Sbjct: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWP 478
Query: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526
D +VG L V YM++SRGQ+V + K+ T S+ ++
Sbjct: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538
Query: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584
P + +Y D +++ L++ VQ + K++L K E V L + T
Sbjct: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596
Query: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
++V + A+D ++ + + + M V + Y+ G G ++ VFQ GL
Sbjct: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652
>gi|115298678 complement component 3 precursor [Homo sapiens]
Length = 1663
Score = 224 bits (572), Expect = 4e-58
Identities = 212/785 (27%), Positives = 360/785 (45%), Gaps = 85/785 (10%)
Query: 687 RKHFPETWIWLDTNMGYR-----IYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741
R FPE+W+W ++ + + + DSIT+W +S+ G+ P E
Sbjct: 764 RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGI-CVADPFE 822
Query: 742 LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIE--KSDKFDILMTSNEI 799
+ Q FFI L LPYSV+R E+ + ++NY + E+KV +E + F L T+
Sbjct: 823 VTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNY-RQNQELKVRVELLHNPAFCSLATTKR- 880
Query: 800 NATGHQQTLLVPSEDGATVLFPIRP--THLGEIPITVTALSPTASDAVTQMILVKAEGIE 857
HQQT+ +P + +V + I P T L E+ + SD V + + V EGI
Sbjct: 881 ---RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIR 937
Query: 858 KSYSQSI-LLDLTDNRLQSTLK------TLSFSFPPNTVTGSERVQITAIGDVLGPSING 910
+ + ++ LD + K LS P +Q T + + +++
Sbjct: 938 MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
Query: 911 --LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEK---ALSFMRQGYQREL 965
L LI P GCGEQNMI P + + YL + +Q EK AL +++GY ++L
Sbjct: 998 ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
Query: 966 LYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWL-KGHQKSN 1024
+++ +F+AF P STWL+A+V++ F A I ID VL WL QK +
Sbjct: 1058 AFRQPSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
Query: 1025 GEFWDPGRVIHSELQGG----NKSPVTLTAYIVTSLLGYR---KYQPNI---DVQESIHF 1074
G F + VIH E+ GG N+ + LTA+++ SL + + Q N + ++ F
Sbjct: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF 1175
Query: 1075 LESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDS 1134
LE+ + + +YT+A+ YAL+ +G K LT ++ W +L
Sbjct: 1176 LEANY-MNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR----WEDPGKQL--- 1227
Query: 1135 WQPRSLDIEVAAYALLSHFLQFQTSEGI-PIMRWLSRQRNSLGGFASTQDTTVALKALSE 1193
++E +YALL+ LQ + + + P++RWL+ QR GG+ STQ T + +AL++
Sbjct: 1228 -----YNVEATSYALLA-LLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQ 1281
Query: 1194 FAA-LMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGF 1252
+ + + N+ V++ PS S + I + LL++ E + ++A G G
Sbjct: 1282 YQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEE--TKENEGFTVTAEGKGQ 1339
Query: 1253 AICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV-------KENKDDLNHVDLNVCTSF 1305
+ +Y+ KA + FDL V + K +D N + L +CT +
Sbjct: 1340 GTLSVVTMYHAKAKDQLTCNK-------FDLKVTIKPAPETEKRPQDAKNTMILEICTRY 1392
Query: 1306 SGPGRSGMALMEVNLLSGFMVPSE-----AISLSETVKKVEY-----DHGKLNLYLDSVN 1355
G + M+++++++++GF ++ A + + K E D L +YLD V+
Sbjct: 1393 RGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVS 1452
Query: 1356 ETQ-FCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCD-LCSDVQGC 1413
++ C+ + F V Q +V + YY R Y+ E + + LC D + C
Sbjct: 1453 HSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRD-ELC 1511
Query: 1414 RPCED 1418
R E+
Sbjct: 1512 RCAEE 1516
Score = 104 bits (260), Expect = 5e-22
Identities = 127/536 (23%), Positives = 240/536 (44%), Gaps = 49/536 (9%)
Query: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQ-WLSQQSDLGVI 189
+FIQTDK +Y P V +RI T+ P ++ + I++P+ ++Q LS Q+ LGV+
Sbjct: 130 LFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVL 189
Query: 190 SKTFQLSSHPILGDWSIQVQVND---QTYYQSFQVSEYVLPKFEVTLQ--TPLYCSMNSK 244
++ + +G W I+ + Q + F+V EYVLP FEV ++ Y N K
Sbjct: 190 PLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEK 249
Query: 245 HLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFK----INGSANFSFNDEEMK 300
L TITA++ YGK V+G + F + ++ ++ ++ K +GS + K
Sbjct: 250 GLEVTITARFLYGKKVEGTAFVIF-GIQDGEQRISLPESLKRIPIEDGSGEVVLS---RK 305
Query: 301 NVMDS-SNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTV 359
++D N +E DL T + S + + + + + Y I F
Sbjct: 306 VLLDGVQNPRAE--DLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKY 363
Query: 360 LKPSLNFTATVKVTRADGN---QLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQ 416
KP + F V VT DG+ ++ + + + V ++TQ + S + +QK
Sbjct: 364 FKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQK----- 418
Query: 417 KINYTVPQSGTFKIEFPILEDSSE-LQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDE 475
++ TV T K E E ++ +Q Y S+ +H S +T ++ E
Sbjct: 419 PLSITV---RTKKQELSEAEQATRTMQALPYSTVGNSNNYLH---LSVLRTELR---PGE 469
Query: 476 NIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGK------QNSTMFSLTPENSWTPKA 529
+ V + + +++ +Y+++++G+L+ G+ Q+ + L+ + P
Sbjct: 470 TLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSF 529
Query: 530 CVIVYY----IEDDGEIISDVLKIPVQ--LVFKNKIKLYWSKVKAE-PSEKVSLRISVTQ 582
++ YY E+++D + + V+ V +K S+ + P ++++L+I
Sbjct: 530 RLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDH 589
Query: 583 PDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
+V +VAVDK V ++N N +T + +E + G G + VF + GL
Sbjct: 590 GARVV-LVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGL 644
>gi|38016947 complement component 5 preproprotein [Homo sapiens]
Length = 1676
Score = 183 bits (465), Expect = 9e-46
Identities = 190/783 (24%), Positives = 356/783 (45%), Gaps = 90/783 (11%)
Query: 682 SSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741
S P +R +FPE+W+W + R ++ + +PDS+T+W G IS + G+ + T V+
Sbjct: 761 SKPEIRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADT-VK 816
Query: 742 LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINA 801
+ F+ F+ +N+PYSV+RGE+ L+ T++NY + V K + + TS E
Sbjct: 817 AKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCV---KMSAVEGICTS-ESPV 872
Query: 802 TGHQQTLL-------VPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAE 854
HQ T V V F + P +G I + + + + + + V E
Sbjct: 873 IDHQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEILVKTLRVVPE 932
Query: 855 GIEKSYSQSILLDLTDNRLQSTL---KTLSFSFPPNTVTGSERVQITAI-----GDVLGP 906
G+++ + LD + T+ K + P + V +E +I ++ G++L
Sbjct: 933 GVKRESYSGVTLD--PRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA 990
Query: 907 SIN--GLASLIRMPYGCGEQNMINFAPNIYILDYLT--------------KKKQLTDNLK 950
++ G+ L +P G E +++ P Y+ YL +K++L LK
Sbjct: 991 VLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLK 1050
Query: 951 EKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVL 1010
E LS M Y+ D S+S + S STWL+AF LR + + Y++ +QN +
Sbjct: 1051 EGMLSIMS--------YRNADYSYSVWKG--GSASTWLTAFALRVLGQVNKYVEQNQNSI 1100
Query: 1011 HRTYTWL-KGHQKSNGEFWDPGRVIHSELQG-----GNKSPVTLTAYIVTSLLGYRKYQP 1064
+ WL + +Q NG F + + +LQG ++ + LTA+ V + P
Sbjct: 1101 CNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICP 1160
Query: 1065 NIDVQESIHFLES---EFSRGISDNYTLALITYALS--SVGSPKAKEALNMLTWRAEQEG 1119
+ + ++ ++ E + +TLA+ YALS P+ + ++ L A +G
Sbjct: 1161 LVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKG 1220
Query: 1120 G---MQFWVSS----ESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQR 1172
+FW + +S + ++ R +E AYALL+ + P+++WLS ++
Sbjct: 1221 NPPIYRFWKDNLQHKDSSVPNTGTARM--VETTAYALLTSLNLKDINYVNPVIKWLSEEQ 1278
Query: 1173 NSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQT 1232
GGF STQDT A++ L+E++ L+ R ++ + V+ + + + T L +
Sbjct: 1279 RYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKM-TDKNFLGRP 1337
Query: 1233 AELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQ-EAFDLDVAVKENK 1291
E+ + V + GFG + ++V V + +S S + + D++ +
Sbjct: 1338 VEVLLNDDLIV---STGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGY 1394
Query: 1292 DDLNHVDLNVCTSFSGPGR------SGMALMEVNLLSGFMVPSEAI-SLSETVKKVEYDH 1344
+ ++ + C S+ P R S A+M+++L +G E + +L E V ++ D+
Sbjct: 1395 GNSDYKRIVACASYK-PSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDY 1453
Query: 1345 ----GKLNLYLDSVNETQF-CVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYN-SE 1398
G + L L+S+ + F CV F+V A+ ++ +Y+ P +Q Y+ S
Sbjct: 1454 QIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSN 1513
Query: 1399 VKL 1401
+K+
Sbjct: 1514 IKI 1516
Score = 140 bits (352), Expect = 1e-32
Identities = 169/660 (25%), Positives = 292/660 (44%), Gaps = 66/660 (10%)
Query: 28 FLVTAPGIIRPGGNVTIGVELL---EHCPSQVTVKAELLKTASNLTVSV-LEAEGVFEKG 83
++++AP I R G + I +++ E + +++K+ K S + V L +E F+
Sbjct: 23 YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82
Query: 84 SFKTLTLPSLP--LNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYK 141
+ T+ LP N +Y L V + FS S R+ +FI TDK +Y
Sbjct: 83 AILTIQPKQLPGGQNPVSYVY-LEVVSKH-----FSKSKRMPITYDNGFLFIHTDKPVYT 136
Query: 142 PKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS-KTFQLSSHPI 200
P Q VK R+ +L D KP K + DP+ + + + + +G+IS F++ S+P
Sbjct: 137 PDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDM-VEEIDHIGIISFPDFKIPSNPR 195
Query: 201 LGDWSIQVQVNDQ---TYYQSFQVSEYVLPKFEVTLQTPLYCSM---NSKHLNGTITAKY 254
G W+I+ + + T F+V EYVLP F V+++ P Y + N K+ TI A+Y
Sbjct: 196 YGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIE-PEYNFIGYKNFKNFEITIKARY 254
Query: 255 TYGKPV-KGDVTLTF-LPLSFWGKKKNITK-----TFKINGSANFSFNDEEMKNVMDSSN 307
Y K V + DV +TF + +K + + T ING A +F+ E +
Sbjct: 255 FYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSE------TAVK 308
Query: 308 GLSEY-LDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLN 365
LS Y L+ + + I TV ES G S + + Y + LKP +
Sbjct: 309 ELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIP 368
Query: 366 FTATVKVTRA-----DGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
+ V+V + G +TL + T+ T S S + + V
Sbjct: 369 YPIKVQVKDSLDQLVGGVPVTLNAQ------TIDVNQETSDLDPSKSVTRVDDGVASFVL 422
Query: 421 TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
+P SG +EF + D+ +L + ++A SL S S YI + + VG
Sbjct: 423 NLP-SGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSL--SQSYLYIDWTDNHKALLVG 479
Query: 481 SPFELVVSGNK----RLKELSYMVVSRGQLVAVGKQNS------TMFSLTPENSWTPKAC 530
++V+ ++ +Y+++S+G+++ G + ++ + P +
Sbjct: 480 EHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSR 539
Query: 531 VIVYYI---EDDGEIISDVLKIPVQLVFKNKIKLYWS--KVKAEPSEKVSLRISVTQPDS 585
++VYYI E E++SD + + ++ N+++++ S P + VSL ++ T DS
Sbjct: 540 LLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMA-TGMDS 598
Query: 586 IVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDAN 645
V + AVD +V + +E V LE + G G +N+ VF GL LT+AN
Sbjct: 599 WVALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNAN 658
>gi|169218213 PREDICTED: similar to complement component C3, partial
[Homo sapiens]
Length = 1295
Score = 180 bits (456), Expect = 1e-44
Identities = 158/541 (29%), Positives = 258/541 (47%), Gaps = 55/541 (10%)
Query: 687 RKHFPETWIWLDTNMGYR-----IYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741
R FPE+W+W ++ + + + DSIT+W +S+ G+ P E
Sbjct: 764 RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGI-CVADPFE 822
Query: 742 LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIE--KSDKFDILMTSNEI 799
+ Q FFI L LPYSV+R E+ + ++NY + E+KV +E + F L T+
Sbjct: 823 VTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNY-RQNQELKVRVELLHNPAFCSLATTKR- 880
Query: 800 NATGHQQTLLVPSEDGATVLFPIRP--THLGEIPITVTALSPTASDAVTQMILVKAEGIE 857
HQQT+ +P + +V + I P T L E+ + SD V + + V EGI
Sbjct: 881 ---RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIR 937
Query: 858 KSYSQSI-LLDLTDNRLQSTLK------TLSFSFPPNTVTGSERVQITAIGDVLGPSING 910
+ + ++ LD + K LS P +Q T + + +++
Sbjct: 938 MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
Query: 911 --LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEK---ALSFMRQGYQREL 965
L LI P GCGEQNMI P + + YL + +Q EK AL +++GY ++L
Sbjct: 998 ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
Query: 966 LYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWL-KGHQKSN 1024
+++ +F+AF P STWL+A+V++ F A I ID VL WL QK +
Sbjct: 1058 AFRQPSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
Query: 1025 GEFWDPGRVIHSELQGG----NKSPVTLTAYIVTSLLGYR---KYQPNI---DVQESIHF 1074
G F + VIH E+ GG N+ + LTA+++ SL + + Q N + ++ F
Sbjct: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF 1175
Query: 1075 LESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDS 1134
LE+ + + +YT+A+ YAL+ +G K LT ++ W +L
Sbjct: 1176 LEANY-MNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR----WEDPGKQL--- 1227
Query: 1135 WQPRSLDIEVAAYALLSHFLQFQTSEGI-PIMRWLSRQRNSLGGFASTQDTTVALKALSE 1193
++E +YALL+ LQ + + + P++RWL+ QR GG+ STQ T + +AL++
Sbjct: 1228 -----YNVEATSYALLA-LLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQ 1281
Query: 1194 F 1194
+
Sbjct: 1282 Y 1282
Score = 105 bits (263), Expect = 2e-22
Identities = 126/535 (23%), Positives = 238/535 (44%), Gaps = 47/535 (8%)
Query: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQ-WLSQQSDLGVI 189
+FIQTDK +Y P V +RI T+ P ++ + I++P+ ++Q LS Q+ LGV+
Sbjct: 130 LFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVL 189
Query: 190 SKTFQLSSHPILGDWSIQVQVND---QTYYQSFQVSEYVLPKFEVTLQ--TPLYCSMNSK 244
++ + +G W I+ + Q + F+V EYVLP FEV ++ Y N K
Sbjct: 190 PLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEK 249
Query: 245 HLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFK----INGSANFSFNDEEMK 300
L TITA++ YGK V+G + F + ++ ++ ++ K +GS + K
Sbjct: 250 GLEVTITARFLYGKKVEGTAFVIF-GIQDGEQRISLPESLKRIPIEDGSGEVVLS---RK 305
Query: 301 NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
++D L DL T + S + + + + + Y I F
Sbjct: 306 VLLDGVQNLRAE-DLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYF 364
Query: 361 KPSLNFTATVKVTRADGN---QLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQK 417
KP + F V VT DG+ ++ + + + V ++TQ + S + +QK
Sbjct: 365 KPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQK-----P 419
Query: 418 INYTVPQSGTFKIEFPILEDSSE-LQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDEN 476
++ TV T K E E ++ +Q Y S+ +H S +T ++ E
Sbjct: 420 LSITV---RTKKQELSEAEQATRTMQALPYSTVGNSNNYLH---LSVLRTELR---PGET 470
Query: 477 IKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGK------QNSTMFSLTPENSWTPKAC 530
+ V + + +++ +Y+++++G+L+ G+ Q+ + L+ + P
Sbjct: 471 LNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFR 530
Query: 531 VIVYY----IEDDGEIISDVLKIPVQ--LVFKNKIKLYWSKVKAE-PSEKVSLRISVTQP 583
++ YY E+++D + + V+ V +K S+ + P ++++L+I
Sbjct: 531 LVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHG 590
Query: 584 DSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
+V +VAVDK V ++N N +T + +E + G G + VF + GL
Sbjct: 591 ARVV-LVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGL 644
>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
Length = 750
Score = 177 bits (450), Expect = 5e-44
Identities = 141/500 (28%), Positives = 228/500 (45%), Gaps = 74/500 (14%)
Query: 517 FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSL 576
F L+ P A + VY + GEI++D ++ V FK+K+ + +S + P SL
Sbjct: 146 FPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASL 205
Query: 577 RISVTQPDSIVGIVAVDKSVNLMNASNDITME---NVVHELELYNTGYY----------- 622
+ P + AVD +V L+ + ++ E N+V +E Y Y+
Sbjct: 206 YLQAA-PVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDP 264
Query: 623 ----LGMFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERF 664
MF N + + + GL V T+ + K + + +
Sbjct: 265 CIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLPLPKPL 324
Query: 665 MEENEG----HIVDIHDFSLGSSPH------------VRKHFPETWIWLDTNMGYRIYQE 708
E E H V S G VR +FPETW+W ++
Sbjct: 325 YLETENYGPMHSVPSRIASSGIRGENADYVEQAIIQTVRTNFPETWMWDLVSVDSSGSAN 384
Query: 709 FEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEI 768
+PD+IT W A+GF ++ D+G G+++T L+ QPFFI + P+SV++ E+F L +
Sbjct: 385 LSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVSQPFFIEIASPFSVVQNEQFDLIV 443
Query: 769 TIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLG 828
F+YL E+ V +E+S ++ + + +IN + ++ + T ++ I P LG
Sbjct: 444 NAFSYLNTCVEISVQVEESQNYEANINTWKINGSE-----VIQAGGRKTNIWTIIPKKLG 498
Query: 829 EIPITVTALSPTAS---------------DAVTQMILVKAEGIEKSYSQSILLDLTDNRL 873
++ ITV A S +S D V + LV+ EGIEK +QS L+ T+
Sbjct: 499 KVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEKERTQSFLI-CTEGAK 557
Query: 874 QSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNI 933
S L P + V GS R T +GD+LG ++ L +++MPYG GEQN A +
Sbjct: 558 ASKQGVL--DLPNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGGGEQNAALLASDT 614
Query: 934 YILDYLTKKKQLTDNLKEKA 953
Y+LDYL +QLT+ ++ KA
Sbjct: 615 YVLDYLKSTEQLTEEVQSKA 634
>gi|239758130 PREDICTED: similar to complement component 4B (Childo
blood group), partial [Homo sapiens]
Length = 666
Score = 117 bits (294), Expect = 6e-26
Identities = 136/518 (26%), Positives = 204/518 (39%), Gaps = 91/518 (17%)
Query: 989 SAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQG---GNKSP 1045
+AFVL+ A + + L T WL Q+++G F D VIH +QG GN
Sbjct: 1 TAFVLKVLSLAQEQVGGSREKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDET 60
Query: 1046 VTLTAYIVTSL-----------LGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITY 1094
V LTA++ +L K + + ++ FL + S G+ + A+ Y
Sbjct: 61 VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAY 120
Query: 1095 ALSSVGSPKAKE--ALNMLTWRAEQEGGMQFWVSSESKLSDSWQPR-------------- 1138
AL+ +P A N L A++ G +W S S++ P
Sbjct: 121 ALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAP 180
Query: 1139 SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGGFASTQDTTVALKALSEF-AA 1196
+L IE AYALL L +E WL+RQ + GGF STQDT +AL ALS + A
Sbjct: 181 ALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIA 240
Query: 1197 LMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLL-QTAELAVVQPTAVNISANGFGFAIC 1255
TE + VT++ + +NR + EL + +N+ G
Sbjct: 241 SHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTL 300
Query: 1256 QLNVVYNV-KASGSSRRRRSIQ-------------NQEAFDLDVAVKENKDD-------- 1293
++ YNV ++ + I+ N++ D + KDD
Sbjct: 301 KVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPV 360
Query: 1294 ------------------------LNHVDLNVCTSFSGP-GRSGMALMEVNLLSGFMV-- 1326
+ V VC +G G SGMA+ +V LLSGF
Sbjct: 361 TPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALR 420
Query: 1327 --PSEAISLSET-VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVD 1383
+ SLS+ V E + + LY DSV ++ CV AV+ V Q AS ++ D
Sbjct: 421 ADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYD 480
Query: 1384 YYEPRRQAVRSYNSEVK------LSSCDLCSDVQGCRP 1415
YY P R+ Y + K L S ++C +G P
Sbjct: 481 YYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCP 518
>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 278
Score = 87.4 bits (215), Expect = 9e-17
Identities = 40/117 (34%), Positives = 71/117 (60%), Gaps = 1/117 (0%)
Query: 686 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
VR +FPETW+W ++ +PD+IT W A+GF ++ D+G G+++T L+
Sbjct: 67 VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVS 125
Query: 746 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINAT 802
QPFFI + P+SV++ E+F L + +F+Y E+ V +E+S ++ + + +IN +
Sbjct: 126 QPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANINTWKINGS 182
>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
blood group) [Homo sapiens]
Length = 270
Score = 72.4 bits (176), Expect = 3e-12
Identities = 54/198 (27%), Positives = 95/198 (47%), Gaps = 14/198 (7%)
Query: 122 LSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLS 181
L F ++R +F+QTD+ +Y P Q V++R+ L +P ++ +++++ +++
Sbjct: 52 LLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KE 110
Query: 182 QQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP-- 236
+ F + G W I + +D S F+V +YVLP FEV + TP
Sbjct: 111 VYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGK 169
Query: 237 LYCSMNSKHLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGS 289
Y HL+ I A+Y YGKPV+G + F L GKK ++T +NG
Sbjct: 170 PYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQ 229
Query: 290 ANFSFNDEEMKNVMDSSN 307
++ S + E ++ ++ N
Sbjct: 230 SHISLSKAEFQDALEKLN 247
>gi|239755748 PREDICTED: ovostatin [Homo sapiens]
Length = 257
Score = 57.4 bits (137), Expect = 1e-07
Identities = 53/187 (28%), Positives = 79/187 (42%), Gaps = 27/187 (14%)
Query: 1220 FLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNV----KASGSSRRRRSI 1275
F ++ HNRLL+Q +E+ P + G G Q + YNV KASG S +
Sbjct: 80 FQVNGHNRLLVQRSEVTQA-PGQYTVDVEGHGCTFIQATLKYNVLLPKKASGFSLSLEIV 138
Query: 1276 QNQE--AFDLDVAVKENKDDLNHVDLNVCTSFSG-PGRSGMALMEVNLLSGFMVPSEAIS 1332
+N AFDL V +K ++G +S M +++V +LSGF +I
Sbjct: 139 KNYSSTAFDLTVTLK----------------YTGIRNKSSMVVIDVKMLSGFTPTMSSIE 182
Query: 1333 LSET---VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRR 1389
E V K E + + YL++ ++ V N Q A + DYYE
Sbjct: 183 ELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSNLVFNIQPAPAMVYDYYEKEE 242
Query: 1390 QAVRSYN 1396
A+ YN
Sbjct: 243 YALAFYN 249
>gi|169214179 PREDICTED: similar to complement component 3 [Homo
sapiens]
Length = 390
Score = 56.2 bits (134), Expect = 2e-07
Identities = 54/237 (22%), Positives = 101/237 (42%), Gaps = 29/237 (12%)
Query: 1201 ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1260
+ N+ V++ PS S + I + LL++ E + ++A G G + +
Sbjct: 17 QELNLDVSLQLPSRSSKITHRIHWESASLLRSEETK--ENEGFTVTAEGKGQGTLSVVTM 74
Query: 1261 YNVKASGSSRRRRSIQNQEAFDLDVAVK-------ENKDDLNHVDLNVCTSFSGPGRSGM 1313
Y+ KA + FDL V +K +D N + L +CT + G + M
Sbjct: 75 YHAKAKDQLTCNK-------FDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATM 127
Query: 1314 ALMEVNLLSGFMVPSE-----AISLSETVKKVEY-----DHGKLNLYLDSVNETQ-FCVN 1362
+++++++++GF ++ A + + K E D L +YLD V+ ++ C+
Sbjct: 128 SILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLA 187
Query: 1363 IPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCD-LCSDVQGCRPCED 1418
+ F V Q +V + YY R Y+ E + + LC D + CR E+
Sbjct: 188 FKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRD-ELCRCAEE 243
>gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sapiens]
Length = 189
Score = 46.6 bits (109), Expect = 2e-04
Identities = 37/135 (27%), Positives = 61/135 (45%), Gaps = 20/135 (14%)
Query: 1068 VQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEAL-NMLTWRAEQEGGMQFWVS 1126
++ ++ LE+ G+++ Y A++ YA + G K E+L L A + + +W
Sbjct: 50 LRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYWER 109
Query: 1127 SESKLSDS------WQPRSLDIEVAAYALLSHFLQFQTSEGIP-------IMRWLSRQRN 1173
++ W P S E + Y LL+ S IP I++WL++Q N
Sbjct: 110 ERKPKTEEFPSFIPWAP-SAQTEKSCYVLLAVI-----SRKIPDLTYASKIVQWLAQQMN 163
Query: 1174 SLGGFASTQDTTVAL 1188
S GGF+S Q V L
Sbjct: 164 SHGGFSSNQVINVGL 178
>gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 261
Score = 46.6 bits (109), Expect = 2e-04
Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 517 FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSL 576
F L+ P A + VY + GEI++D ++ V FK+K+ + +S + P SL
Sbjct: 146 FPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASL 205
Query: 577 RISVTQPDSIVGIVAVDKSVNLMNASNDITMENV 610
+ P + AVD++V L+ + ++ E+V
Sbjct: 206 CLQAA-PVLFCALRAVDRNVLLLKSEQQLSAESV 238
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 34.7 bits (78), Expect = 0.68
Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 6/117 (5%)
Query: 833 TVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGS 892
TV L P AVT++ +K E IEK + + LD T Q+ +K + P +
Sbjct: 216 TVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQR--QNVVKPIDNPPHPGSTKPL 273
Query: 893 ERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNL 949
++V I G+++ ++ P E N IN A I +KK D+L
Sbjct: 274 KKVIIEETGNLIQTIDVPDSTTAAAP----ENNPINLANVIAATGTTSKKNSSQDDL 326
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 34.7 bits (78), Expect = 0.68
Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 6/117 (5%)
Query: 833 TVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGS 892
TV L P AVT++ +K E IEK + + LD T Q+ +K + P +
Sbjct: 375 TVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQR--QNVVKPIDNPPHPGSTKPL 432
Query: 893 ERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNL 949
++V I G+++ ++ P E N IN A I +KK D+L
Sbjct: 433 KKVIIEETGNLIQTIDVPDSTTAAAP----ENNPINLANVIAATGTTSKKNSSQDDL 485
>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
Length = 727
Score = 33.1 bits (74), Expect = 2.0
Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 15/98 (15%)
Query: 578 ISVTQPDSIVGIVAVDKSVNLMNASND--------ITMENVVHELELYNTGYYLGMFMNS 629
+SV PD I + + + ++ N D TMEN +H Y+ G ++G+ S
Sbjct: 450 LSVWFPDVIKPLQSDEYALLTRNVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKS 509
Query: 630 F----AVFQECGLWVLTDANL---TKDYIDGVYDNAEY 660
+VF+ C +T N +ID V+DN ++
Sbjct: 510 VTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDF 547
>gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]
Length = 95
Score = 32.7 bits (73), Expect = 2.6
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 1313 MALMEVNLLSGFMVPSEAISLSET---VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNF 1369
M +++V +LSGF +I E V K E + + YL++ ++
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60
Query: 1370 KVSNTQDASVSIVDYYEPRRQAVRSYN 1396
V N Q A + DYYE A+ YN
Sbjct: 61 LVFNIQPAPAMVYDYYEKEEYALAFYN 87
>gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sapiens]
Length = 95
Score = 32.7 bits (73), Expect = 2.6
Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 3/87 (3%)
Query: 1313 MALMEVNLLSGFMVPSEAISLSET---VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNF 1369
M +++V +LSGF +I E V K E + + YL++ ++
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60
Query: 1370 KVSNTQDASVSIVDYYEPRRQAVRSYN 1396
V N Q A + DYYE A+ YN
Sbjct: 61 LVFNIQPAPAMVYDYYEKEEYALAFYN 87
>gi|89264696 angiopoietin-like 4 protein isoform b precursor [Homo
sapiens]
Length = 368
Score = 32.0 bits (71), Expect = 4.4
Identities = 42/164 (25%), Positives = 58/164 (35%), Gaps = 27/164 (16%)
Query: 1 MQGPPLLTAAHLLCVCTAALAVAPG-------PRFLVTAPGIIRPGGNVTIGVELLEHCP 53
M G P AA +LC TA L A G PRF + G + +G L EH
Sbjct: 1 MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREH-- 58
Query: 54 SQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDE 113
AE ++ + L A G +G+ + LP P R E
Sbjct: 59 ------AERTRSQLSALERRLSACGSACQGTEGSTDLPLAP------------ESRVDPE 100
Query: 114 ILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDF 157
+L S T+L + RI + ++ RI L S F
Sbjct: 101 VLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQF 144
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,642,910
Number of Sequences: 37866
Number of extensions: 2231097
Number of successful extensions: 5206
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 4992
Number of HSP's gapped (non-prelim): 83
length of query: 1445
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1330
effective length of database: 13,892,928
effective search space: 18477594240
effective search space used: 18477594240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.