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Search of human proteins with 23510358
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23510358 RIO kinase 1 isoform 2 [Homo sapiens]
(327 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23510356 RIO kinase 1 isoform 1 [Homo sapiens] 655 0.0
gi|23510358 RIO kinase 1 isoform 2 [Homo sapiens] 655 0.0
gi|22325377 sudD suppressor of bimD6 homolog [Homo sapiens] 176 3e-44
gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens] 48 1e-05
gi|229331971 RIO kinase 2 isoform 2 [Homo sapiens] 48 1e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 40 0.002
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 39 0.005
gi|62243374 MAD1-like 1 protein [Homo sapiens] 39 0.005
gi|62243369 MAD1-like 1 protein [Homo sapiens] 39 0.005
gi|62243332 MAD1-like 1 protein [Homo sapiens] 39 0.005
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 39 0.008
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 39 0.008
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 38 0.011
gi|151301228 formin binding protein 3 [Homo sapiens] 38 0.011
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 38 0.014
gi|34878777 ring finger protein 20 [Homo sapiens] 38 0.014
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 38 0.014
gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens] 38 0.014
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 37 0.018
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 37 0.018
gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens] 37 0.024
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 37 0.031
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 37 0.031
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 36 0.041
gi|56118310 nuclear casein kinase and cyclin-dependent kinase su... 36 0.041
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 36 0.041
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 36 0.041
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens] 36 0.053
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens] 36 0.053
gi|168229156 NFKB activating protein [Homo sapiens] 36 0.053
>gi|23510356 RIO kinase 1 isoform 1 [Homo sapiens]
Length = 568
Score = 655 bits (1689), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR 60
MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR
Sbjct: 242 MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR 301
Query: 61 ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC 120
ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC
Sbjct: 302 ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC 361
Query: 121 ANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVD 180
ANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVD
Sbjct: 362 ANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVD 421
Query: 181 EEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQK 240
EEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQK
Sbjct: 422 EEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQK 481
Query: 241 VPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEA 300
VPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEA
Sbjct: 482 VPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEA 541
Query: 301 QREKRKNKIPKHVKKRKEKTAKTKKGK 327
QREKRKNKIPKHVKKRKEKTAKTKKGK
Sbjct: 542 QREKRKNKIPKHVKKRKEKTAKTKKGK 568
>gi|23510358 RIO kinase 1 isoform 2 [Homo sapiens]
Length = 327
Score = 655 bits (1689), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR 60
MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR
Sbjct: 1 MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR 60
Query: 61 ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC 120
ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC
Sbjct: 61 ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC 120
Query: 121 ANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVD 180
ANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVD
Sbjct: 121 ANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVD 180
Query: 181 EEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQK 240
EEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQK
Sbjct: 181 EEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQK 240
Query: 241 VPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEA 300
VPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEA
Sbjct: 241 VPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEA 300
Query: 301 QREKRKNKIPKHVKKRKEKTAKTKKGK 327
QREKRKNKIPKHVKKRKEKTAKTKKGK
Sbjct: 301 QREKRKNKIPKHVKKRKEKTAKTKKGK 327
>gi|22325377 sudD suppressor of bimD6 homolog [Homo sapiens]
Length = 519
Score = 176 bits (446), Expect = 3e-44
Identities = 88/188 (46%), Positives = 125/188 (66%), Gaps = 8/188 (4%)
Query: 1 MVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSESKAR 60
+++ WAEKEM NL R+ A IPCP ++L+ H+LVMSFIG D +PAP LK V+L+ + +
Sbjct: 324 IIRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMK 383
Query: 61 ELYLQVIQYMRRMYQDARLVHADLSEFNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDC 120
E Y Q + MR++Y + LVHADLSE+NML+H G V++IDVSQSVE HPH LEFL +DC
Sbjct: 384 EAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDC 443
Query: 121 ANVNDFFMRHSV-AVMTVRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHV 179
NV+ FF + V ++ RELF V+ +IT +N +L++ + E+ ++DHV
Sbjct: 444 RNVSQFFQKGGVKEALSERELFNAVSGLNITADNEADFLAEIEAL-------EKMNEDHV 496
Query: 180 DEEVFKRA 187
+ K A
Sbjct: 497 QKNGRKAA 504
>gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens]
Length = 552
Score = 48.1 bits (113), Expect = 1e-05
Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 14/128 (10%)
Query: 6 AEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSES---KAREL 62
A KE + L + P P+PI H +VM I + P + +V+ S +A EL
Sbjct: 158 AMKEFAYMKALYERKFPVPKPIDYNRHAVVMELI--NGYPLCQIHHVEDPASVYDEAMEL 215
Query: 63 YLQVIQYMRRMYQDARLVHADLSEFNMLY-HGGGVYIIDVSQSVEHDHPHALEFLRKDCA 121
+++ + L+H D +EFN++ + +ID Q V HP+A + +D
Sbjct: 216 IVKLANH--------GLIHGDFNEFNLILDESDHITMIDFPQMVSTSHPNAEWYFDRDVK 267
Query: 122 NVNDFFMR 129
+ DFFM+
Sbjct: 268 CIKDFFMK 275
>gi|229331971 RIO kinase 2 isoform 2 [Homo sapiens]
Length = 474
Score = 48.1 bits (113), Expect = 1e-05
Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 14/128 (10%)
Query: 6 AEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSES---KAREL 62
A KE + L + P P+PI H +VM I + P + +V+ S +A EL
Sbjct: 158 AMKEFAYMKALYERKFPVPKPIDYNRHAVVMELI--NGYPLCQIHHVEDPASVYDEAMEL 215
Query: 63 YLQVIQYMRRMYQDARLVHADLSEFNMLY-HGGGVYIIDVSQSVEHDHPHALEFLRKDCA 121
+++ + L+H D +EFN++ + +ID Q V HP+A + +D
Sbjct: 216 IVKLANH--------GLIHGDFNEFNLILDESDHITMIDFPQMVSTSHPNAEWYFDRDVK 267
Query: 122 NVNDFFMR 129
+ DFFM+
Sbjct: 268 CIKDFFMK 275
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/170 (24%), Positives = 66/170 (38%), Gaps = 21/170 (12%)
Query: 167 QRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQ 226
Q+ K E S++D +D + + + ++ K K+E + +D+IL +
Sbjct: 5 QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKG---KKKKEKKKQDFDEDDILKE 61
Query: 227 T------VTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSS----ECSDTDSEEQGDH 276
G+K D V P EN EE T D + G D DSEE D
Sbjct: 62 LEELSLEAQGIKADRETVAVKPT--ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDK 119
Query: 277 ARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKG 326
K T P ++ M + + NK+PK K + +K+ K G
Sbjct: 120 DSKSKKTAKPKVE------MYSGSDDDDDFNKLPKKAKGKAQKSNKKWDG 163
Score = 33.9 bits (76), Expect = 0.20
Identities = 38/152 (25%), Positives = 63/152 (41%), Gaps = 23/152 (15%)
Query: 180 DEEVFKRAYIPRTLNEVKNYER-----DMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKD 234
D+ FK + + E K ER + + KLKE++ + TG K
Sbjct: 219 DDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKE------------ELETGKKDQ 266
Query: 235 LSGVQKVPALLENQVEERTCSDSEDI-GSSECSDTDSEEQGDHARPKKHTTDPDIDKKER 293
+ E V+ + D+ I S E ++T + + D+ KK DKK++
Sbjct: 267 SKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKK-----DKKKK 321
Query: 294 KKMVKEAQREKRKNKIPKHVKKRKEKTAKTKK 325
K +E ++EK+K VK +E AK K+
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQEALAKLKE 353
>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
Length = 1844
Score = 39.3 bits (90), Expect = 0.005
Identities = 32/129 (24%), Positives = 50/129 (38%), Gaps = 23/129 (17%)
Query: 192 TLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEE 251
TLN + M+ ++E + N+L + + + S + P LL+ Q+E
Sbjct: 918 TLNSKLKSGNSAAVFMRTRKE---FTEEVRNLLLEEIRWSNPEFSLKKYFPLLLKKQIEH 974
Query: 252 RTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPK 311
+ S SEC K + D+ KE K+ + EA+ K K K P
Sbjct: 975 QVLS-------SECHS-------------KQELEADVSHKETKRKLVEAENSKSKRKKPN 1014
Query: 312 HVKKRKEKT 320
K EKT
Sbjct: 1015 EYSKNLEKT 1023
>gi|62243374 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 15/156 (9%)
Query: 150 THENMDAYLSKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKL 209
THE + L K + + ++ R+ D E+ Y P+ ++ E D++ K+
Sbjct: 389 THEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAE---DMVQKV 445
Query: 210 KEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTD 269
M AQ L ++L G ++ +LE +++ S S+E S
Sbjct: 446 HSHSAEMEAQLSQAL--------EELGGQKQRADMLEMELKMLKSQSS----SAEQSFLF 493
Query: 270 SEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 305
S E+ D R K + + + E +K + EAQ E+R
Sbjct: 494 SREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 529
>gi|62243369 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 15/156 (9%)
Query: 150 THENMDAYLSKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKL 209
THE + L K + + ++ R+ D E+ Y P+ ++ E D++ K+
Sbjct: 389 THEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAE---DMVQKV 445
Query: 210 KEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTD 269
M AQ L ++L G ++ +LE +++ S S+E S
Sbjct: 446 HSHSAEMEAQLSQAL--------EELGGQKQRADMLEMELKMLKSQSS----SAEQSFLF 493
Query: 270 SEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 305
S E+ D R K + + + E +K + EAQ E+R
Sbjct: 494 SREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 529
>gi|62243332 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 15/156 (9%)
Query: 150 THENMDAYLSKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKL 209
THE + L K + + ++ R+ D E+ Y P+ ++ E D++ K+
Sbjct: 389 THEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAE---DMVQKV 445
Query: 210 KEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTD 269
M AQ L ++L G ++ +LE +++ S S+E S
Sbjct: 446 HSHSAEMEAQLSQAL--------EELGGQKQRADMLEMELKMLKSQSS----SAEQSFLF 493
Query: 270 SEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 305
S E+ D R K + + + E +K + EAQ E+R
Sbjct: 494 SREEADTLRLKVEELEGERSRLEEEKRMLEAQLERR 529
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 38.5 bits (88), Expect = 0.008
Identities = 52/262 (19%), Positives = 103/262 (39%), Gaps = 43/262 (16%)
Query: 100 DVSQSVEHDHPHALE-FLRKDCANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYL 158
++ +SVE D E F + D D F+ +T+ + + + + ++
Sbjct: 661 ELQRSVEFDREFWKENFFKSD--ETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHV 718
Query: 159 SKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMD-------------- 204
SK +R K ++ S E+ F+ I E +N D D
Sbjct: 719 SKERNFKEERDKIKKES-----EKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEES 773
Query: 205 IIMKLKEEDMAMNAQQDNILYQTVTGLK------KDLSGVQKVPALLENQVEERTCSDSE 258
I + L E+++ + Q+ +I K KD+ +++ E +++ S+ +
Sbjct: 774 IGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKD 833
Query: 259 DIGSSECSDTDSEE-------------QGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 305
+ SEC D E+ +G+ ++ D +K R+KM ++ +EK
Sbjct: 834 KLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKP 893
Query: 306 KNKIPKHVKKRKEKTAKTKKGK 327
+ + +H+ + KEK KK K
Sbjct: 894 EKE--RHLAESKEKHLMEKKNK 913
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 38.5 bits (88), Expect = 0.008
Identities = 52/262 (19%), Positives = 103/262 (39%), Gaps = 43/262 (16%)
Query: 100 DVSQSVEHDHPHALE-FLRKDCANVNDFFMRHSVAVMTVRELFEFVTDPSITHENMDAYL 158
++ +SVE D E F + D D F+ +T+ + + + + ++
Sbjct: 684 ELQRSVEFDREFWKENFFKSD--ETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHV 741
Query: 159 SKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMD-------------- 204
SK +R K ++ S E+ F+ I E +N D D
Sbjct: 742 SKERNFKEERDKIKKES-----EKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEES 796
Query: 205 IIMKLKEEDMAMNAQQDNILYQTVTGLK------KDLSGVQKVPALLENQVEERTCSDSE 258
I + L E+++ + Q+ +I K KD+ +++ E +++ S+ +
Sbjct: 797 IGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKD 856
Query: 259 DIGSSECSDTDSEE-------------QGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 305
+ SEC D E+ +G+ ++ D +K R+KM ++ +EK
Sbjct: 857 KLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKP 916
Query: 306 KNKIPKHVKKRKEKTAKTKKGK 327
+ + +H+ + KEK KK K
Sbjct: 917 EKE--RHLAESKEKHLMEKKNK 936
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 38.1 bits (87), Expect = 0.011
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 251 ERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNK-- 308
++ +DSE + + +T++ + + P KKE+K KE +EK+K K
Sbjct: 807 DKPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEK 866
Query: 309 ----IPKHVKKRKEKTAKTKKGK 327
PK K RKEK +TK K
Sbjct: 867 KKSPKPKKKKHRKEKEERTKGKK 889
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 38.1 bits (87), Expect = 0.011
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 250 EERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKI 309
E R+ S+ SE S S++ ++ ++H +D ER+K KE RE K++
Sbjct: 822 ESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDR- 880
Query: 310 PKHVKKRKEKTAKTKKGK 327
+ + K K+ K K GK
Sbjct: 881 TRQRSESKHKSPKKKTGK 898
Score = 33.9 bits (76), Expect = 0.20
Identities = 33/176 (18%), Positives = 70/176 (39%), Gaps = 4/176 (2%)
Query: 155 DAYLSKAMEIASQRTKEERSSQDHVD---EEVFKRAYIPRTLNEVKNYERDMDIIMKLKE 211
++ L KA +R KEE + + + K+A P L+ V R+ + +
Sbjct: 695 NSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRER-FVKEPAF 753
Query: 212 EDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTDSE 271
ED+ + +++ I + L+ + + ++ S S+ D DS
Sbjct: 754 EDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSH 813
Query: 272 EQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
+ R + + E ++ K++++ K+K+K +H E A+ +K K
Sbjct: 814 SKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKDK 869
Score = 29.6 bits (65), Expect = 3.8
Identities = 20/79 (25%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Query: 227 TVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDP 286
TVT ++ + + PA+ + VE + + E +D +++ + ++P K T
Sbjct: 304 TVTISTEEQAQLTSTPAIQDQSVEVSSNTGEETSKQETVADFTPKKEEEESQPAKKTYTW 363
Query: 287 DIDKKERKKMVKEAQREKR 305
+ K+E K+ KE +EKR
Sbjct: 364 N-TKEEAKQAFKELLKEKR 381
>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 37.7 bits (86), Expect = 0.014
Identities = 19/46 (41%), Positives = 28/46 (60%)
Query: 280 KKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKK 325
KK TT +K++ K+ KE ++EK K K + KK+K+K K KK
Sbjct: 66 KKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKK 111
Score = 35.8 bits (81), Expect = 0.053
Identities = 23/116 (19%), Positives = 57/116 (49%), Gaps = 4/116 (3%)
Query: 209 LKEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDT 268
++E D + ++ +++ + + K+ +K + + ++ T + + + + T
Sbjct: 1 MQELDKGVAMEKVHVITEKESAWKRG----RKKKTTKKKKKKKTTMKKKKKTTTKKKTTT 56
Query: 269 DSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTK 324
++++ + TT + +K++ K+ KE ++EK K K K KK+K+K K K
Sbjct: 57 KTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKK 112
Score = 35.0 bits (79), Expect = 0.091
Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 281 KHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
K TT +KE++K KE ++EK K K + KK+K+K K KK K
Sbjct: 66 KKTTTTTTKEKEKEKE-KEKEKEKEKEKEKEKEKKKKKKKKKKKKKK 111
Score = 32.7 bits (73), Expect = 0.45
Identities = 15/43 (34%), Positives = 27/43 (62%)
Query: 280 KKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAK 322
K+ + + +K++ K+ KE ++EK+K K K KK+K+ AK
Sbjct: 74 KEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAK 116
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 37.7 bits (86), Expect = 0.014
Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 256 DSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKER-----KKMVKEAQREKRKNKIP 310
DSED+ S + S+E + + K+ + + +++E+ ++ KE +RE+ K K+
Sbjct: 539 DSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKEREREKQKL- 597
Query: 311 KHVKKRKEKTAKTKKGK 327
K +K ++ +KGK
Sbjct: 598 KESEKERDSAKDKEKGK 614
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 37.7 bits (86), Expect = 0.014
Identities = 28/152 (18%), Positives = 65/152 (42%), Gaps = 7/152 (4%)
Query: 166 SQRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILY 225
S + S ++E F Y + + ++ R + K +E+++ ++ +L
Sbjct: 160 SNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLK 219
Query: 226 QTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTD 285
+ +KK L +K + +E+ E+ + + + H + ++ D
Sbjct: 220 RRFE-IKKKLKTAKK------KEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRD 272
Query: 286 PDIDKKERKKMVKEAQREKRKNKIPKHVKKRK 317
+DKK + +A+REKRKN+ + + K++
Sbjct: 273 EKLDKKSQAMEELKAEREKRKNRTAELLAKKQ 304
Score = 33.5 bits (75), Expect = 0.26
Identities = 32/107 (29%), Positives = 48/107 (44%), Gaps = 17/107 (15%)
Query: 233 KDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKE 292
KD S P E +V + SDS SS SD+ SE++ H + + D+
Sbjct: 141 KDSSAESSAPE--EGEVSD---SDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRAR 195
Query: 293 RKKMV-KEAQRE-----------KRKNKIPKHVKKRKEKTAKTKKGK 327
++M KE ++E KR+ +I K +K K+K K KK K
Sbjct: 196 LEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKK 242
Score = 33.1 bits (74), Expect = 0.35
Identities = 35/147 (23%), Positives = 64/147 (43%), Gaps = 7/147 (4%)
Query: 138 RELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVDEEVFKRAYIPRTLNEVK 197
+ELF + + + + K ++ A ++ K+E+ + ++E K I +
Sbjct: 206 QELFNRIEKREVLKRRFE--IKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSH 263
Query: 198 NYERDMDIIMKLKEEDMAMN---AQQDNILYQTVTGL-KKDLSGVQKVPALLENQVEERT 253
N ER KL ++ AM A+++ +T L KK +V + E + E+
Sbjct: 264 NKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDK 323
Query: 254 CSDSEDIGSSECSDTDSEEQGDHARPK 280
S+ D SS S +D EE+ + PK
Sbjct: 324 SSEKSD-RSSRTSSSDEEEEKEEIPPK 349
>gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]
Length = 628
Score = 37.7 bits (86), Expect = 0.014
Identities = 27/91 (29%), Positives = 47/91 (51%), Gaps = 5/91 (5%)
Query: 33 VLVMSFIGKDDMPAPLLKNVQLSESKARELYLQVIQYMRRMYQDARLVHADLSEFNMLYH 92
V+VM + + D+ + + QLSE +AR + Q++ + +Q+ R+VH DL N+L
Sbjct: 126 VIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQN-RVVHRDLKLENILLD 184
Query: 93 -GGGVYIIDVSQSVEHDHPHALEFLRKDCAN 122
G + I D S + H +FL+ C +
Sbjct: 185 ANGNIKIADFGLSNLY---HQGKFLQTFCGS 212
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 37.4 bits (85), Expect = 0.018
Identities = 26/78 (33%), Positives = 42/78 (53%), Gaps = 12/78 (15%)
Query: 246 ENQVEERTCSDSEDIGSSECSDTDS-EEQGDHARPKKHTTDPDIDKKER---KKMVKEAQ 301
+ ++EE + ED G+ E DT E+ + +KH +D D +K R +K KE +
Sbjct: 56 DGELEE---GELEDDGAEETQDTSGGPERSRKEKGEKHHSDSDEEKSHRRLKRKRKKERE 112
Query: 302 REKRKNKIPKHVKKRKEK 319
+EKR++K K+RK K
Sbjct: 113 KEKRRSK-----KRRKSK 125
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 37.4 bits (85), Expect = 0.018
Identities = 24/118 (20%), Positives = 59/118 (50%), Gaps = 3/118 (2%)
Query: 210 KEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSECSDTD 269
+EE+ M Q+ + + L + L ++K P+ E + ER + + + +
Sbjct: 467 EEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQE 526
Query: 270 SEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
E++ + R ++ + +++K++ K+ E +R++ K K ++++KEK + +K K
Sbjct: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK---ELERQKEKEKELQKMK 581
Score = 32.7 bits (73), Expect = 0.45
Identities = 32/166 (19%), Positives = 75/166 (45%), Gaps = 8/166 (4%)
Query: 158 LSKAMEIASQRTKE-ERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDII-MKLKEEDMA 215
L K E ++ +E +R Q ++E+ K R + + + E++ ++ K KE+++
Sbjct: 519 LEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQ 578
Query: 216 MNAQQDNILYQTVTGLKKDLSGVQKVPAL---LENQVEERTCSDSEDIGSSECSDTDSEE 272
+Q+ K + + P L +E Q E +C+ E+ + SE+
Sbjct: 579 KMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEK 638
Query: 273 QGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKE 318
+ A P H T+P+ + R ++ ++ +K+ P+ +++++
Sbjct: 639 E---ATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQ 681
Score = 28.9 bits (63), Expect = 6.5
Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 10/61 (16%)
Query: 250 EERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKI 309
E+ SD ++ GS+ + +SE+QG A + E KK E K ++I
Sbjct: 330 EQLNFSDDDEQGSNSPKENNSEDQGSKAS----------ENNENKKETDEVSNTKSSSQI 379
Query: 310 P 310
P
Sbjct: 380 P 380
>gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens]
Length = 1135
Score = 37.0 bits (84), Expect = 0.024
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
Query: 215 AMNAQQDNILYQTVTGLKKDL-SGVQKVP-ALLENQVEERTCSDSE-DIGSSECSDT-DS 270
+M D++ +T L + L S VP + + ++ T S+S+ I E DT DS
Sbjct: 927 SMKITADDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDTKDS 986
Query: 271 EEQGDHARPKKHTTDPDIDKKE--RKKMVKEAQREKRKNKIPKHVKKRKEKTAKTK 324
+EQG H +++T D R+K ++ A+R RK PKH K EK + +
Sbjct: 987 KEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRKG--PKHSGKTAEKITQQR 1040
>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 36.6 bits (83), Expect = 0.031
Identities = 17/39 (43%), Positives = 27/39 (69%)
Query: 289 DKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
+KKE++K K+ +++K+K K K KK+K+K K KK K
Sbjct: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRK 142
Score = 35.4 bits (80), Expect = 0.070
Identities = 20/55 (36%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Query: 271 EEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKK 325
E++ + + KK KK++KK K+ +++KRK K K +KRK+K K KK
Sbjct: 107 EKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRK-RKRKRKRKKKRKKKKK 160
Score = 35.0 bits (79), Expect = 0.091
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 277 ARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
A P H + ++E KK ++ +++K+K K K KK+K+K K KK K
Sbjct: 88 AGPSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKK 138
Score = 35.0 bits (79), Expect = 0.091
Identities = 16/52 (30%), Positives = 30/52 (57%)
Query: 276 HARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
H P++ +K++KK K+ +++K+K K K KK+K+K + +K K
Sbjct: 97 HGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK 148
Score = 35.0 bits (79), Expect = 0.091
Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 271 EEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
EE+ + + KK KK++KK K+ +++K+K K K +KRK K K +K K
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKK-RKRKRKRKRKRKKKRKKK 158
Score = 35.0 bits (79), Expect = 0.091
Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 264 ECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKT 323
E + + E++ + KK KK++KK K+ ++ KRK K K KKRK+K KT
Sbjct: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRK-RKRKKKRKKKKKKT 162
Score = 34.3 bits (77), Expect = 0.16
Identities = 16/59 (27%), Positives = 34/59 (57%)
Query: 269 DSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
+ +++ + + KK KK++KK K+ +++K+K K + K++++K K KK K
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161
Score = 33.9 bits (76), Expect = 0.20
Identities = 15/48 (31%), Positives = 30/48 (62%)
Query: 278 RPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKK 325
R +K + + KK++KK K+ +++K+K K K KK++++ K K+
Sbjct: 102 REEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKR 149
Score = 31.6 bits (70), Expect = 1.0
Identities = 15/53 (28%), Positives = 30/53 (56%)
Query: 273 QGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKK 325
Q + + K+ KK++KK K+ +++K+K K K K+++++ K KK
Sbjct: 101 QREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 36.6 bits (83), Expect = 0.031
Identities = 18/57 (31%), Positives = 32/57 (56%)
Query: 271 EEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
+++ + + T + + + +RK+ KE ++EK K K K +KRKEK + KK K
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Score = 32.7 bits (73), Expect = 0.45
Identities = 15/70 (21%), Positives = 37/70 (52%)
Query: 256 DSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKK 315
++E+ +E ++ + E++G +K KK+ K+ K ++E+ + K + KK
Sbjct: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK 68
Query: 316 RKEKTAKTKK 325
+KE+ + ++
Sbjct: 69 KKEEEEREEE 78
Score = 30.0 bits (66), Expect = 2.9
Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 3/51 (5%)
Query: 278 RPKKHTTDPDIDKKERKKMVKEAQR-EKRKNKIPKHVKKRKEKTAKTKKGK 327
+ KK T + + ++ ++ KE +R EKRK K + K++K+KT +T+K K
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEK--RKEKEKKKKTKETEKRK 53
Score = 29.6 bits (65), Expect = 3.8
Identities = 16/75 (21%), Positives = 35/75 (46%)
Query: 248 QVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKN 307
+ E+R + E+ EE+ ++ + + ++KE + K+ ++ +RK
Sbjct: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107
Query: 308 KIPKHVKKRKEKTAK 322
+ + KKR+ KT K
Sbjct: 108 EEEEKKKKRRRKTKK 122
Score = 28.5 bits (62), Expect = 8.5
Identities = 17/70 (24%), Positives = 32/70 (45%)
Query: 246 ENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 305
E + EE+ E + EE+ + + ++ + KK++K+ KE + EK+
Sbjct: 54 EKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Query: 306 KNKIPKHVKK 315
K + K KK
Sbjct: 114 KKRRRKTKKK 123
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 36.2 bits (82), Expect = 0.041
Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 246 ENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKR 305
+ Q E + +D E G E +D E Q D R K+ D + D+KE +K ++ +R+K
Sbjct: 212 KTQTERQRETDRE--GERE-TDRRRERQRDRDRGKER--DRERDRKEERKKERKKERKKE 266
Query: 306 KNKIPKHVKKRKEKTAKTKKG 326
+ + K K+R++K K +G
Sbjct: 267 RKEKKKEEKRREDKKRKWGEG 287
Score = 32.3 bits (72), Expect = 0.59
Identities = 16/61 (26%), Positives = 33/61 (54%)
Query: 267 DTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKG 326
+TD E + + R ++ D D K+ ++ ++ +R+K + K K +K K+K K ++
Sbjct: 220 ETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
Query: 327 K 327
K
Sbjct: 280 K 280
Score = 28.5 bits (62), Expect = 8.5
Identities = 35/168 (20%), Positives = 67/168 (39%), Gaps = 17/168 (10%)
Query: 167 QRTKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQ 226
+R ++E+ + + D E R + K ER+ D + +E D +++ Q
Sbjct: 101 ERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRE-RERDRDREKERER---Q 156
Query: 227 TVTGLKKDLSGVQKVPALLENQVEERTCSDSE---DIGSSECSDTDSEEQGDHARPKKHT 283
T +KD G ++ E E + E D ++ + E Q D R ++
Sbjct: 157 T----EKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRK 212
Query: 284 T------DPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKK 325
T + D + + +E QR++ + K + RKE+ K +K
Sbjct: 213 TQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERK 260
>gi|56118310 nuclear casein kinase and cyclin-dependent kinase
substrate 1 [Homo sapiens]
Length = 243
Score = 36.2 bits (82), Expect = 0.041
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 8/160 (5%)
Query: 169 TKEERSSQDHVDEEVFKRAYIPRTLNEVKNYERDMDIIMKLKEEDMAMNAQQDNILYQTV 228
TK+ RSS E + + E D D+ K + A +++ + ++ V
Sbjct: 34 TKKIRSSP----REAKNKRRSGKNSQEDSEDSEDKDVKTKKDDSHSAEDSEDEKEDHKNV 89
Query: 229 TGLKKDLS-GVQKVPALLENQVEERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPD 287
++ S K +L V + ED + D+ S+E D +D
Sbjct: 90 RQQRQAASKAASKQREMLMEDVGSEEEQEEEDEAPFQEKDSGSDE--DFLMEDDDDSDYG 147
Query: 288 IDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
KK+ KKMVK+++ E+++ K+PK + + T KGK
Sbjct: 148 SSKKKNKKMVKKSKPERKEKKMPK-PRLKATVTPSPVKGK 186
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 36.2 bits (82), Expect = 0.041
Identities = 19/74 (25%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
Query: 250 EERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKI 309
+E+ ++D D + +++ D R ++ + D DK++ K+ KE +REK ++K
Sbjct: 407 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK- 465
Query: 310 PKHVKKRKEKTAKT 323
K++K+K ++T
Sbjct: 466 EIDEKRKKDKKSRT 479
Score = 30.4 bits (67), Expect = 2.2
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 250 EERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKI 309
++R S S S+ + H+R K+ T I +KER VKE REK + +
Sbjct: 346 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER---VKEKDREKERER- 401
Query: 310 PKHVKKRKEKTAKTKKGK 327
+K +EK + K K
Sbjct: 402 ----EKEREKEKERGKNK 415
Score = 30.0 bits (66), Expect = 2.9
Identities = 15/62 (24%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 267 DTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKR-KEKTAKTKK 325
+ + E + + + K+ + D DK+ K K+ ++++ + + +H K R KEK + K
Sbjct: 396 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 455
Query: 326 GK 327
K
Sbjct: 456 EK 457
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 36.2 bits (82), Expect = 0.041
Identities = 19/74 (25%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
Query: 250 EERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKI 309
+E+ ++D D + +++ D R ++ + D DK++ K+ KE +REK ++K
Sbjct: 291 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK- 349
Query: 310 PKHVKKRKEKTAKT 323
K++K+K ++T
Sbjct: 350 EIDEKRKKDKKSRT 363
Score = 30.4 bits (67), Expect = 2.2
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 250 EERTCSDSEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKI 309
++R S S S+ + H+R K+ T I +KER VKE REK + +
Sbjct: 230 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER---VKEKDREKERER- 285
Query: 310 PKHVKKRKEKTAKTKKGK 327
+K +EK + K K
Sbjct: 286 ----EKEREKEKERGKNK 299
Score = 30.0 bits (66), Expect = 2.9
Identities = 15/62 (24%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 267 DTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKR-KEKTAKTKK 325
+ + E + + + K+ + D DK+ K K+ ++++ + + +H K R KEK + K
Sbjct: 280 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 339
Query: 326 GK 327
K
Sbjct: 340 EK 341
>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
Length = 259
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/131 (21%), Positives = 57/131 (43%), Gaps = 16/131 (12%)
Query: 206 IMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSEC 265
++ ++E+ + + +++++ +++G + G KVP Q + + +D +D E
Sbjct: 116 LVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVP-----QKKVKLAADEDDDDDDE- 169
Query: 266 SDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVK----------K 315
D D ++ D ++ + K R K AQ+ + K K K
Sbjct: 170 EDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFK 229
Query: 316 RKEKTAKTKKG 326
++EKT KT KG
Sbjct: 230 KQEKTPKTPKG 240
>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
Length = 294
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/131 (21%), Positives = 57/131 (43%), Gaps = 16/131 (12%)
Query: 206 IMKLKEEDMAMNAQQDNILYQTVTGLKKDLSGVQKVPALLENQVEERTCSDSEDIGSSEC 265
++ ++E+ + + +++++ +++G + G KVP Q + + +D +D E
Sbjct: 116 LVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVP-----QKKVKLAADEDDDDDDE- 169
Query: 266 SDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVK----------K 315
D D ++ D ++ + K R K AQ+ + K K K
Sbjct: 170 EDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFK 229
Query: 316 RKEKTAKTKKG 326
++EKT KT KG
Sbjct: 230 KQEKTPKTPKG 240
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 35.8 bits (81), Expect = 0.053
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 24/102 (23%)
Query: 242 PALLENQVEE----RTCSDSEDIG----------SSECSDTDSEEQG--DHARPKKHTTD 285
P+LL+ + EE + S+ E IG S + + DS+E + PKK TT
Sbjct: 115 PSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTS 174
Query: 286 PDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAKTKKGK 327
++E+K K++ R K ++K K+RK+K++K K K
Sbjct: 175 ASTSEEEKK---KKSSRSKERSK-----KRRKKKSSKRKHKK 208
Score = 35.0 bits (79), Expect = 0.091
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 11/69 (15%)
Query: 257 SEDIGSSECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKR 316
SED S S+TDS ++ + R KK KKE+KK + + +K+++K K R
Sbjct: 210 SEDSDSDSDSETDSSDEDNKRRAKK------AKKKEKKKKHRSKKYKKKRSK-----KSR 258
Query: 317 KEKTAKTKK 325
KE + + K
Sbjct: 259 KESSDSSSK 267
Score = 31.2 bits (69), Expect = 1.3
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 7/65 (10%)
Query: 263 SECSDTDSEEQGDHARPKKHTTDPDIDKKERKKMVKEAQREKRKNKIPKHVKKRKEKTAK 322
SE SD+DS+ + D ++D D ++ +K KE +++ R K K K+ K +
Sbjct: 210 SEDSDSDSDSETD-------SSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESS 262
Query: 323 TKKGK 327
K
Sbjct: 263 DSSSK 267
Score = 30.4 bits (67), Expect = 2.2
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 10/71 (14%)
Query: 262 SSECSDTDSEEQGDHARPKKHTTDPDIDK--------KERKKMVKEAQR--EKRKNKIPK 311
S E S +++ + KK++ D D D ++ K+ K+A++ +K+K++ K
Sbjct: 189 SKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKK 248
Query: 312 HVKKRKEKTAK 322
+ KKR +K+ K
Sbjct: 249 YKKKRSKKSRK 259
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,640,674
Number of Sequences: 37866
Number of extensions: 521945
Number of successful extensions: 5323
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 233
Number of HSP's that attempted gapping in prelim test: 3840
Number of HSP's gapped (non-prelim): 1270
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.