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Search of human proteins with 23397464
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23397464 gap junction protein, beta 4 [Homo sapiens]
(266 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23397464 gap junction protein, beta 4 [Homo sapiens] 565 e-161
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 334 4e-92
gi|54607056 connexin 31 [Homo sapiens] 319 1e-87
gi|13128960 connexin 31 [Homo sapiens] 319 1e-87
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 262 2e-70
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 262 2e-70
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 262 3e-70
gi|159032020 gap junction protein, beta 6 [Homo sapiens] 257 8e-69
gi|158966714 gap junction protein, beta 6 [Homo sapiens] 257 8e-69
gi|158966717 gap junction protein, beta 6 [Homo sapiens] 257 8e-69
gi|40254837 gap junction protein, beta 6 [Homo sapiens] 257 8e-69
gi|42558283 gap junction protein beta 2 [Homo sapiens] 255 2e-68
gi|22779877 connexin 46 [Homo sapiens] 198 5e-51
gi|55953076 connexin 50 [Homo sapiens] 194 5e-50
gi|62865885 connexin 37 [Homo sapiens] 194 9e-50
gi|4504001 connexin 43 [Homo sapiens] 188 4e-48
gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 188 4e-48
gi|32483412 connexin 40 [Homo sapiens] 184 5e-47
gi|6631083 connexin 40 [Homo sapiens] 184 5e-47
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 173 2e-43
gi|122939172 connexin 45 [Homo sapiens] 155 3e-38
gi|69122473 connexin 45 [Homo sapiens] 155 3e-38
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 149 3e-36
gi|145699105 connexin40.1 [Homo sapiens] 126 2e-29
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 116 2e-26
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 116 2e-26
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 107 1e-23
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 75 5e-14
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 75 5e-14
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 75 5e-14
>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
Length = 266
Score = 565 bits (1457), Expect = e-161
Identities = 266/266 (100%), Positives = 266/266 (100%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC
Sbjct: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120
PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL
Sbjct: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120
Query: 121 SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRP 180
SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRP
Sbjct: 121 SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRP 180
Query: 181 TEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRCRECLPDTCPPYVLS 240
TEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRCRECLPDTCPPYVLS
Sbjct: 181 TEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRCRECLPDTCPPYVLS 240
Query: 241 QGGHPEDGNSVLMKAGSAPVDAGGYP 266
QGGHPEDGNSVLMKAGSAPVDAGGYP
Sbjct: 241 QGGHPEDGNSVLMKAGSAPVDAGGYP 266
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 334 bits (857), Expect = 4e-92
Identities = 153/226 (67%), Positives = 177/226 (78%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
MNW+ +GLLSGVNKYST RIWLS+VFIFRVLVY+V AE VW D+ KDF CNT+QPGC
Sbjct: 1 MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120
NVC+DEFFPVSHVRLWALQLILVTCPSLLVVMHVAYRE +E++H HG N+ LY N
Sbjct: 61 SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRLYLNP 120
Query: 121 SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRP 180
KKRGGLWWTY+ SL+FKA+VD FLY+FH Y Y +P VV C +PCP+ VDC+IS+P
Sbjct: 121 GKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFISKP 180
Query: 181 TEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRC 226
+EK +FT FMV TAAICILLNL E+ YLV KRC E R + C
Sbjct: 181 SEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMC 226
>gi|54607056 connexin 31 [Homo sapiens]
Length = 270
Score = 319 bits (818), Expect = 1e-87
Identities = 159/270 (58%), Positives = 191/270 (70%), Gaps = 16/270 (5%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W LQ LLSGVNKYST RIWLSVVF+FRVLVYVVAAE VW DEQKDF CNTKQPGC
Sbjct: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120
NVCYD +FP+S++RLWALQLI VTCPSLLV++HVAYREERER+H KHG LYDN
Sbjct: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120
Query: 121 SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVAC-SVEPCPHTVDCYISR 179
KK GGLWWTYL SLIFK ++ FLY+ H L+ ++MPR+V C +V PCP+ VDCYI+R
Sbjct: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180
Query: 180 PTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRCRECLP-------D 232
PTEKK+FTYFMV +A+CI+L + E+ YL+ C + H+ C P
Sbjct: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLI---CHRVLRGLHKDKPRGGCSPSSSASRAS 237
Query: 233 TCP-PYVLSQGGH--PEDGNSVLMKAGSAP 259
TC + L + G P+ GN+ L SAP
Sbjct: 238 TCRCHHKLVEAGEVDPDPGNNKLQ--ASAP 265
>gi|13128960 connexin 31 [Homo sapiens]
Length = 270
Score = 319 bits (818), Expect = 1e-87
Identities = 159/270 (58%), Positives = 191/270 (70%), Gaps = 16/270 (5%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W LQ LLSGVNKYST RIWLSVVF+FRVLVYVVAAE VW DEQKDF CNTKQPGC
Sbjct: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120
NVCYD +FP+S++RLWALQLI VTCPSLLV++HVAYREERER+H KHG LYDN
Sbjct: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNA 120
Query: 121 SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVAC-SVEPCPHTVDCYISR 179
KK GGLWWTYL SLIFK ++ FLY+ H L+ ++MPR+V C +V PCP+ VDCYI+R
Sbjct: 121 GKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIAR 180
Query: 180 PTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGPRHRRPRCRECLP-------D 232
PTEKK+FTYFMV +A+CI+L + E+ YL+ C + H+ C P
Sbjct: 181 PTEKKIFTYFMVGASAVCIVLTICELCYLI---CHRVLRGLHKDKPRGGCSPSSSASRAS 237
Query: 233 TCP-PYVLSQGGH--PEDGNSVLMKAGSAP 259
TC + L + G P+ GN+ L SAP
Sbjct: 238 TCRCHHKLVEAGEVDPDPGNNKLQ--ASAP 265
>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 262 bits (670), Expect = 2e-70
Identities = 118/217 (54%), Positives = 161/217 (74%), Gaps = 4/217 (1%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
MNW L LLSGVN++ST + R+WLSV+FIFR++V VVAAE VW DE+ F+CNT QPGC
Sbjct: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120
+VCYD+FFP+SHVRLW+LQLILV+ P+LLV MHVA+++ E+K G P + +
Sbjct: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV 120
Query: 121 SKKR----GGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCY 176
+ + G LWWTY++S++F+ +A F+Y+F+ LY Y M R+V C V PCP+TVDC+
Sbjct: 121 KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
Query: 177 ISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRC 213
+SRPTEK VFT FM+ + ICI+LN++EV YL+ + C
Sbjct: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRAC 217
>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 262 bits (670), Expect = 2e-70
Identities = 118/217 (54%), Positives = 161/217 (74%), Gaps = 4/217 (1%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
MNW L LLSGVN++ST + R+WLSV+FIFR++V VVAAE VW DE+ F+CNT QPGC
Sbjct: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120
+VCYD+FFP+SHVRLW+LQLILV+ P+LLV MHVA+++ E+K G P + +
Sbjct: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV 120
Query: 121 SKKR----GGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCY 176
+ + G LWWTY++S++F+ +A F+Y+F+ LY Y M R+V C V PCP+TVDC+
Sbjct: 121 KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
Query: 177 ISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRC 213
+SRPTEK VFT FM+ + ICI+LN++EV YL+ + C
Sbjct: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRAC 217
>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
Length = 223
Score = 262 bits (669), Expect = 3e-70
Identities = 120/211 (56%), Positives = 160/211 (75%), Gaps = 7/211 (3%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W FL+ LLSGVNKYST IWL+VVF+FR+LVY+VAAE VW DEQK+F CN++QPGC
Sbjct: 1 MSWMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120
NVC+D+FFP+S VRLWALQLI+V+ PSLLVV+HVAY E RE++H K LY +
Sbjct: 61 KNVCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKRHRKK-------LYVSP 113
Query: 121 SKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRP 180
GGLW+ YL+SLI K + GFL +F++LY + +P ++ C ++PCP+TVDC+IS+P
Sbjct: 114 GTMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKCDLKPCPNTVDCFISKP 173
Query: 181 TEKKVFTYFMVTTAAICILLNLSEVFYLVGK 211
TEK +F F+V T+ +CI+LN E+ +LV K
Sbjct: 174 TEKTIFILFLVITSCLCIVLNFIELSFLVLK 204
>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 257 bits (656), Expect = 8e-69
Identities = 117/218 (53%), Positives = 158/218 (72%), Gaps = 5/218 (2%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W L + GVNK+ST + ++W++V+FIFRV++ VVAA+EVW DEQ+DFVCNT QPGC
Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREERERKHHLKHGPNAPSLYDN 119
NVCYD FFPVSH+RLWALQLI V+ P+LLV MHVA YR E RK N ++
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
Query: 120 LSKKR----GGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDC 175
+ K++ G LWWTY S+ F+ +A F+Y+F+ LY Y +P V+ C ++PCP+ VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
Query: 176 YISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRC 213
+ISRPTEK VFT FM++ + IC+LLN++E+ YL+ K C
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVC 218
>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 257 bits (656), Expect = 8e-69
Identities = 117/218 (53%), Positives = 158/218 (72%), Gaps = 5/218 (2%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W L + GVNK+ST + ++W++V+FIFRV++ VVAA+EVW DEQ+DFVCNT QPGC
Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREERERKHHLKHGPNAPSLYDN 119
NVCYD FFPVSH+RLWALQLI V+ P+LLV MHVA YR E RK N ++
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
Query: 120 LSKKR----GGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDC 175
+ K++ G LWWTY S+ F+ +A F+Y+F+ LY Y +P V+ C ++PCP+ VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
Query: 176 YISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRC 213
+ISRPTEK VFT FM++ + IC+LLN++E+ YL+ K C
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVC 218
>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 257 bits (656), Expect = 8e-69
Identities = 117/218 (53%), Positives = 158/218 (72%), Gaps = 5/218 (2%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W L + GVNK+ST + ++W++V+FIFRV++ VVAA+EVW DEQ+DFVCNT QPGC
Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREERERKHHLKHGPNAPSLYDN 119
NVCYD FFPVSH+RLWALQLI V+ P+LLV MHVA YR E RK N ++
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
Query: 120 LSKKR----GGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDC 175
+ K++ G LWWTY S+ F+ +A F+Y+F+ LY Y +P V+ C ++PCP+ VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
Query: 176 YISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRC 213
+ISRPTEK VFT FM++ + IC+LLN++E+ YL+ K C
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVC 218
>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 257 bits (656), Expect = 8e-69
Identities = 117/218 (53%), Positives = 158/218 (72%), Gaps = 5/218 (2%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W L + GVNK+ST + ++W++V+FIFRV++ VVAA+EVW DEQ+DFVCNT QPGC
Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREERERKHHLKHGPNAPSLYDN 119
NVCYD FFPVSH+RLWALQLI V+ P+LLV MHVA YR E RK N ++
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
Query: 120 LSKKR----GGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDC 175
+ K++ G LWWTY S+ F+ +A F+Y+F+ LY Y +P V+ C ++PCP+ VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
Query: 176 YISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRC 213
+ISRPTEK VFT FM++ + IC+LLN++E+ YL+ K C
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVC 218
>gi|42558283 gap junction protein beta 2 [Homo sapiens]
Length = 226
Score = 255 bits (652), Expect = 2e-68
Identities = 113/218 (51%), Positives = 156/218 (71%), Gaps = 5/218 (2%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W LQ +L GVNK+ST + +IWL+V+FIFR+++ VVAA+EVW DEQ DFVCNT QPGC
Sbjct: 1 MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLK-----HGPNAPS 115
NVCYD +FP+SH+RLWALQLI V+ P+LLV MHVAYR +++ +K +
Sbjct: 61 KNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEE 120
Query: 116 LYDNLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDC 175
+ + G LWWTY S+ F+ +A F+Y+F+ +Y + M R+V C+ PCP+TVDC
Sbjct: 121 IKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDC 180
Query: 176 YISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRC 213
++SRPTEK VFT FM+ + ICILLN++E+ YL+ + C
Sbjct: 181 FVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYC 218
>gi|22779877 connexin 46 [Homo sapiens]
Length = 435
Score = 198 bits (503), Expect = 5e-51
Identities = 99/228 (43%), Positives = 144/228 (63%), Gaps = 18/228 (7%)
Query: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
+W+FL LL ++STV+ ++WL+V+FIFR+LV AAE+VW DEQ DF CNT+QPGC
Sbjct: 3 DWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPGCE 62
Query: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAY-------REERERKHHLKHGPNAP 114
NVCYD FP+SH+R WALQ+I V+ P+L+ + HV + ++ERE + LK +P
Sbjct: 63 NVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESPSP 122
Query: 115 S--LYDNLSKK--------RGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVAC 164
DN S + G L TY+ ++IFK + GF+ + LY +++ + C
Sbjct: 123 KEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLY-GFELKPLYRC 181
Query: 165 SVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKR 212
PCP+TVDC+ISRPTEK +F FM+ A +LLN+ E+++L K+
Sbjct: 182 DRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKK 229
>gi|55953076 connexin 50 [Homo sapiens]
Length = 433
Score = 194 bits (494), Expect = 5e-50
Identities = 100/226 (44%), Positives = 141/226 (62%), Gaps = 20/226 (8%)
Query: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
+W+FL +L VN++STV+ R+WL+V+FIFR+L+ AAE VW DEQ DFVCNT+QPGC
Sbjct: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
Query: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAY--REERERKHH----------LKH 109
NVCYDE FP+SH+RLW LQ+I V+ PSL+ V H + R E +RK
Sbjct: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
Query: 110 GPNAPSLYDNLSKK-------RGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVV 162
GP+ S+ + K G L TY+ +IFK + GF+ + LY +P +
Sbjct: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP-LY 181
Query: 163 ACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYL 208
CS PCP+ VDC++SRPTEK +F FM++ A++ + LN+ E+ +L
Sbjct: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHL 227
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 194 bits (492), Expect = 9e-50
Identities = 99/236 (41%), Positives = 138/236 (58%), Gaps = 25/236 (10%)
Query: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
+W FL+ LL V ++STV+ +IWL+V+FIFR+L+ +A E VW DEQ DF CNT QPGC
Sbjct: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
Query: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGP---------- 111
NVCYD+ FP+SH+R W LQ + V+ P+L+ + HV Y RE + K G
Sbjct: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
Query: 112 -------------NAPSLYDNLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDM 158
D + RG L TY+ S++ K+ ++AGFLY RLY + M
Sbjct: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
Query: 159 PRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCM 214
V C PCP+ VDC++SRPTEK +F FM+ I ++LNL E+ +L+ RC+
Sbjct: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLL-CRCL 236
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 188 bits (478), Expect = 4e-48
Identities = 95/233 (40%), Positives = 134/233 (57%), Gaps = 24/233 (10%)
Query: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
+W+ L LL V YST ++WLSV+FIFR+L+ A E W DEQ F CNT+QPGC
Sbjct: 3 DWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCE 62
Query: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLS 121
NVCYD+ FP+SHVR W LQ+I V+ P+LL + HV Y +E K + K + D ++
Sbjct: 63 NVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVN 122
Query: 122 -----------------------KKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDM 158
K RGGL TY++S++FK+ + FL I +Y + +
Sbjct: 123 VDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIY-GFSL 181
Query: 159 PRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGK 211
V C +PCPH VDC++SRPTEK +F FM+ + + + LN+ E+FY+ K
Sbjct: 182 SAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFK 234
>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
Length = 543
Score = 188 bits (478), Expect = 4e-48
Identities = 98/265 (36%), Positives = 155/265 (58%), Gaps = 29/265 (10%)
Query: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
+W L G+L V+ +ST++ +IWL+++FIFR+LV VAAE+VWDDEQ F CNT+QPGC
Sbjct: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
Query: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR------EERERKHHLKHGPNAPS 115
N+CYD+ FP+S +R W LQ+I V+ PSL+ + H YR + + +K HL+ P
Sbjct: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
Query: 116 LYDNLSKK-------------------RGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDY 156
L ++ +G L TY+L ++ ++ ++ GF+ + LY +
Sbjct: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
Query: 157 DMPRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEI 216
M + C+ PCP+ VDC++SRPTEK +F FM + AAI +LLN+ E+F+L ++ M
Sbjct: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRT 241
Query: 217 FGPRHRRPRCRECLPDTCPPYVLSQ 241
+++ +T PP+ L +
Sbjct: 242 L---YKKSSSEGIEDETGPPFHLKK 263
>gi|32483412 connexin 40 [Homo sapiens]
Length = 358
Score = 184 bits (468), Expect = 5e-47
Identities = 94/248 (37%), Positives = 145/248 (58%), Gaps = 23/248 (9%)
Query: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
+W+FL L V+K+STV+ ++WL+V+FIFR+LV AAE W DEQ DF C+T QPGC
Sbjct: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
Query: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLS 121
NVCYD+ FP+SH+R W LQ+I V+ PSL+ + H + + K L+ A + + S
Sbjct: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
Query: 122 KK---------------------RGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPR 160
+ +G L TY+ S++ + ++ GF+ + +Y + +
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIF-LTT 181
Query: 161 VVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIF-GP 219
+ C PCPH V+CY+SRPTEK VF FM+ AA+ +LL+L+E+++L K+ + F P
Sbjct: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVKP 241
Query: 220 RHRRPRCR 227
R +C+
Sbjct: 242 RQHMAKCQ 249
>gi|6631083 connexin 40 [Homo sapiens]
Length = 358
Score = 184 bits (468), Expect = 5e-47
Identities = 94/248 (37%), Positives = 145/248 (58%), Gaps = 23/248 (9%)
Query: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
+W+FL L V+K+STV+ ++WL+V+FIFR+LV AAE W DEQ DF C+T QPGC
Sbjct: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
Query: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLS 121
NVCYD+ FP+SH+R W LQ+I V+ PSL+ + H + + K L+ A + + S
Sbjct: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
Query: 122 KK---------------------RGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPR 160
+ +G L TY+ S++ + ++ GF+ + +Y + +
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIF-LTT 181
Query: 161 VVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIF-GP 219
+ C PCPH V+CY+SRPTEK VF FM+ AA+ +LL+L+E+++L K+ + F P
Sbjct: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVKP 241
Query: 220 RHRRPRCR 227
R +C+
Sbjct: 242 RQHMAKCQ 249
>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
Length = 515
Score = 173 bits (438), Expect = 2e-43
Identities = 93/236 (39%), Positives = 140/236 (59%), Gaps = 26/236 (11%)
Query: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
+W L L V+ +ST++ +IWL+++FIFR+LV VAAE+VW+DEQ F+CNT+QPGC
Sbjct: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
Query: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-----EERER-KHHLK------- 108
NVCYD+ FP+S +R W LQ+I V+ PSL+ + H YR EER+R K L+
Sbjct: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
Query: 109 -HGPNAPSLYD-----------NLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDY 156
P + N + RG L TY++ + ++ V+ GF+ + LY +
Sbjct: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
Query: 157 DMPRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKR 212
+ + C PCP+ +DC++SRPTEK +F FM + A I + LN+ E+F+L K+
Sbjct: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKK 237
>gi|122939172 connexin 45 [Homo sapiens]
Length = 396
Score = 155 bits (393), Expect = 3e-38
Identities = 82/254 (32%), Positives = 128/254 (50%), Gaps = 47/254 (18%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W+FL LL ++ +ST + +IWL+V+ +FR+++ V E ++ DEQ FVCNT+QPGC
Sbjct: 1 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMH------------------------VA 96
NVCYD F P+SHVR W Q+ILV PS++ + + +
Sbjct: 61 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120
Query: 97 YREERERKHHLKHGPNAPSLYDNLSK----------------------KRGGLWWTYLLS 134
+++ R + + P +Y + + GL Y+L
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180
Query: 135 LIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTA 194
L+ + + GFL + LY + + CS PCPH +DC+ISRPTEK +F M
Sbjct: 181 LLARTVFEVGFLIGQYFLY-GFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVT 239
Query: 195 AICILLNLSEVFYL 208
+C+LLN+ E+ +L
Sbjct: 240 GLCLLLNIWEMLHL 253
>gi|69122473 connexin 45 [Homo sapiens]
Length = 396
Score = 155 bits (393), Expect = 3e-38
Identities = 82/254 (32%), Positives = 128/254 (50%), Gaps = 47/254 (18%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W+FL LL ++ +ST + +IWL+V+ +FR+++ V E ++ DEQ FVCNT+QPGC
Sbjct: 1 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMH------------------------VA 96
NVCYD F P+SHVR W Q+ILV PS++ + + +
Sbjct: 61 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120
Query: 97 YREERERKHHLKHGPNAPSLYDNLSK----------------------KRGGLWWTYLLS 134
+++ R + + P +Y + + GL Y+L
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180
Query: 135 LIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTA 194
L+ + + GFL + LY + + CS PCPH +DC+ISRPTEK +F M
Sbjct: 181 LLARTVFEVGFLIGQYFLY-GFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVT 239
Query: 195 AICILLNLSEVFYL 208
+C+LLN+ E+ +L
Sbjct: 240 GLCLLLNIWEMLHL 253
>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
Length = 294
Score = 149 bits (375), Expect = 3e-36
Identities = 84/215 (39%), Positives = 117/215 (54%), Gaps = 9/215 (4%)
Query: 3 WAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPN 62
WAFL LL V S ++ R+WL V+ IFR+LV V++DEQ++FVCNT QPGC
Sbjct: 4 WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
Query: 63 VCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYD---- 118
CYD FPVSH R W ++L++ P +L V++ +R +E AP L +
Sbjct: 64 TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCA 123
Query: 119 --NLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCY 176
L +R YLLS+ + + FL LY P AC+ PCPHTVDC+
Sbjct: 124 PCALRARRARR--CYLLSVALRLLAELTFLGGQALLYGFRVAPH-FACAGPPCPHTVDCF 180
Query: 177 ISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGK 211
+SRPTEK VF F + LL+++E+ +L+ K
Sbjct: 181 VSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWK 215
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 126 bits (317), Expect = 2e-29
Identities = 72/222 (32%), Positives = 117/222 (52%), Gaps = 12/222 (5%)
Query: 9 LLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPNVCYDEF 68
L+ +N T++ ++W + + R+LV V+A V+ DEQ+ FVCNT QPGC NVCYD F
Sbjct: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
Query: 69 FPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLSK------ 122
PVSH+R W +Q + V PS + ++V +R + P+ +
Sbjct: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFG 129
Query: 123 KRGGLWWT-----YLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYI 177
+RGGL Y++ L+ + ++A F + + L+ + P+ C+ PC VDCY+
Sbjct: 130 ERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCYV 188
Query: 178 SRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGP 219
SRPTEK + F+ +A+ LL L+++ + +R GP
Sbjct: 189 SRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGP 230
>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
Length = 279
Score = 116 bits (291), Expect = 2e-26
Identities = 68/212 (32%), Positives = 107/212 (50%), Gaps = 11/212 (5%)
Query: 5 FLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPNVC 64
FL+ LL+ ++ ST + R+ L V+ FR+++ + V+ DEQ +FVC+T+QPGC C
Sbjct: 5 FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64
Query: 65 YDEFFPVSHVRLWALQLILVTCPSLL--------VVMHVAYREERERKHHLKHGPNAPSL 116
+D F P+S +R W Q+ILV PS L V+ H + + + L G +
Sbjct: 65 FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKEEETLIQGREGNTD 124
Query: 117 YDNLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCY 176
R L W Y+ L + ++ L + + LY + MP AC EPC ++ C
Sbjct: 125 VPGAGSLR--LLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
Query: 177 ISRPTEKKVFTYFMVTTAAICILLNLSEVFYL 208
+SRP+EK +F M + C+L E+ L
Sbjct: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
Length = 439
Score = 116 bits (290), Expect = 2e-26
Identities = 47/115 (40%), Positives = 78/115 (67%), Gaps = 4/115 (3%)
Query: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
M+W+FL LL ++ +ST + ++WL+V+ +FR+++ V E ++ DEQ F CNT+QPGC
Sbjct: 4 MSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGC 63
Query: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR----EERERKHHLKHGP 111
NVCYD F P+SHVR W Q+++++ PS++ + + +R E+ER+ L+ P
Sbjct: 64 DNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRP 118
Score = 74.7 bits (182), Expect = 8e-14
Identities = 36/86 (41%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Query: 123 KRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRPTE 182
+R GL Y+ L+ +AA + FL + LY +++ CS +PCPH VDC++SRPTE
Sbjct: 205 QREGLMRVYVAQLVARAAFEVAFLVGQYLLY-GFEVRPFFPCSRQPCPHVVDCFVSRPTE 263
Query: 183 KKVFTYFMVTTAAICILLNLSEVFYL 208
K VF M + +C+LLNL E+ +L
Sbjct: 264 KTVFLLVMYVVSCLCLLLNLCEMAHL 289
>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
Length = 321
Score = 107 bits (266), Expect = 1e-23
Identities = 47/103 (45%), Positives = 69/103 (66%), Gaps = 1/103 (0%)
Query: 3 WAFLQGLL-SGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
W L+ LL + V ++ST++ RI L+VV IFR+L+ + E V+DDEQ FVCNT QPGC
Sbjct: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
Query: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERK 104
CYD FP+SH+R W Q+I+V PSL + + ++ ++R+
Sbjct: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQRE 106
Score = 72.0 bits (175), Expect = 5e-13
Identities = 39/130 (30%), Positives = 72/130 (55%), Gaps = 2/130 (1%)
Query: 122 KKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYISRPT 181
+++ G+ Y++ ++F+ A++ GFL + LY + +P + C+ PC V+CY+SRPT
Sbjct: 190 RRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIKEVECYVSRPT 248
Query: 182 EKKVFTYFMVTTAAICILLNLSEVFYLVGKRC-MEIFGPRHRRPRCRECLPDTCPPYVLS 240
EK VF FM + IC++LNL+E+ +L ++ + + G + +R E P +
Sbjct: 249 EKTVFLVFMFAVSGICVVLNLAELNHLGWRKIKLAVRGAQAKRKSIYEIRNKDLPRVSVP 308
Query: 241 QGGHPEDGNS 250
G + +S
Sbjct: 309 NFGRTQSSDS 318
>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 75.5 bits (184), Expect = 5e-14
Identities = 34/82 (41%), Positives = 53/82 (64%)
Query: 9 LLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPNVCYDEF 68
LL+ + +ST + R+ V+ FR+++ + V+ DEQ +FVC+T+QPGC C+D F
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 69 FPVSHVRLWALQLILVTCPSLL 90
P+S +R W Q+ILV PS+L
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVL 109
>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 75.5 bits (184), Expect = 5e-14
Identities = 34/82 (41%), Positives = 53/82 (64%)
Query: 9 LLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPNVCYDEF 68
LL+ + +ST + R+ V+ FR+++ + V+ DEQ +FVC+T+QPGC C+D F
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 69 FPVSHVRLWALQLILVTCPSLL 90
P+S +R W Q+ILV PS+L
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVL 109
>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 75.5 bits (184), Expect = 5e-14
Identities = 34/82 (41%), Positives = 53/82 (64%)
Query: 9 LLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPNVCYDEF 68
LL+ + +ST + R+ V+ FR+++ + V+ DEQ +FVC+T+QPGC C+D F
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 69 FPVSHVRLWALQLILVTCPSLL 90
P+S +R W Q+ILV PS+L
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVL 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.141 0.471
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,730,493
Number of Sequences: 37866
Number of extensions: 541489
Number of successful extensions: 1474
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1392
Number of HSP's gapped (non-prelim): 53
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.