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Search of human proteins with 23199971
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23199971 T-cell activation Rho GTPase-activating protein
isoform a [Homo sapiens]
(553 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23199971 T-cell activation Rho GTPase-activating protein isof... 1102 0.0
gi|21314774 T-cell activation Rho GTPase-activating protein isof... 1102 0.0
gi|20270373 T-cell activation Rho GTPase-activating protein isof... 166 5e-41
gi|51479148 Rho GTPase activating protein 20 [Homo sapiens] 92 1e-18
gi|54860105 nadrin isoform 2 [Homo sapiens] 64 4e-10
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 63 8e-10
gi|54860079 nadrin isoform 1 [Homo sapiens] 62 1e-09
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens] 56 8e-08
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 56 1e-07
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ... 54 4e-07
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 54 4e-07
gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a... 54 4e-07
gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b... 53 8e-07
gi|156071465 Rho GTPase activating protein 4 [Homo sapiens] 52 2e-06
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 51 3e-06
gi|208022687 GTPase regulator associated with the focal adhesion... 50 4e-06
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 50 7e-06
gi|7662208 GTPase regulator associated with the focal adhesion k... 50 7e-06
gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens] 49 9e-06
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi... 49 9e-06
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 49 9e-06
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 48 3e-05
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi... 48 3e-05
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi... 48 3e-05
gi|188497642 ARHGAP15 [Homo sapiens] 47 5e-05
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s... 46 1e-04
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 46 1e-04
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 46 1e-04
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 46 1e-04
gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH do... 45 1e-04
>gi|23199971 T-cell activation Rho GTPase-activating protein isoform
a [Homo sapiens]
Length = 553
Score = 1102 bits (2850), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG
Sbjct: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS 120
PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS
Sbjct: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS 120
Query: 121 SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPI 180
SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPI
Sbjct: 121 SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPI 180
Query: 181 VSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEA 240
VSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEA
Sbjct: 181 VSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEA 240
Query: 241 EDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPS 300
EDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPS
Sbjct: 241 EDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPS 300
Query: 301 SPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDH 360
SPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDH
Sbjct: 301 SPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDH 360
Query: 361 VPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEE 420
VPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEE
Sbjct: 361 VPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEE 420
Query: 421 AMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGH 480
AMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGH
Sbjct: 421 AMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGH 480
Query: 481 GLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVF 540
GLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVF
Sbjct: 481 GLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVF 540
Query: 541 EADQFQYAKESYI 553
EADQFQYAKESYI
Sbjct: 541 EADQFQYAKESYI 553
>gi|21314774 T-cell activation Rho GTPase-activating protein isoform
b [Homo sapiens]
Length = 731
Score = 1102 bits (2850), Expect = 0.0
Identities = 553/553 (100%), Positives = 553/553 (100%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG
Sbjct: 179 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 238
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS 120
PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS
Sbjct: 239 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS 298
Query: 121 SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPI 180
SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPI
Sbjct: 299 SDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPI 358
Query: 181 VSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEA 240
VSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEA
Sbjct: 359 VSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSRLESEEA 418
Query: 241 EDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPS 300
EDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPS
Sbjct: 419 EDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSLDASSDSSPVASPS 478
Query: 301 SPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDH 360
SPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDH
Sbjct: 479 SPKRNFFSRHQSFTTKTEKGKPSREIKKHSMSFTFAPHKKVLTKNLSAGSGKSQDFTRDH 538
Query: 361 VPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEE 420
VPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEE
Sbjct: 539 VPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALSVDDVFQGADWERPGSPPSYEE 598
Query: 421 AMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGH 480
AMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGH
Sbjct: 599 AMQGPAARLVASESQTVGSMTVGSMRARMLEAHCLLPPLPPAHHVEDSRHRGSKEPLPGH 658
Query: 481 GLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVF 540
GLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVF
Sbjct: 659 GLSPLPERWKQSRTVHASGDSLGHVSGPGRPELLPLRTVSESVQRNKRDCLVRRCSQPVF 718
Query: 541 EADQFQYAKESYI 553
EADQFQYAKESYI
Sbjct: 719 EADQFQYAKESYI 731
>gi|20270373 T-cell activation Rho GTPase-activating protein isoform
c [Homo sapiens]
Length = 266
Score = 166 bits (420), Expect = 5e-41
Identities = 84/84 (100%), Positives = 84/84 (100%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG
Sbjct: 179 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 238
Query: 61 PNMLTLENDQSLSFEAQKDLNNKV 84
PNMLTLENDQSLSFEAQKDLNNKV
Sbjct: 239 PNMLTLENDQSLSFEAQKDLNNKV 262
>gi|51479148 Rho GTPase activating protein 20 [Homo sapiens]
Length = 1191
Score = 92.0 bits (227), Expect = 1e-18
Identities = 50/143 (34%), Positives = 87/143 (60%), Gaps = 3/143 (2%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
+ ++ ++E++I ++++ D+LPR N++LL++L VLH I ++S N+M + NLA+C+
Sbjct: 455 VSVMDQGNDEEKINTVQRLLDQLPRANVVLLRYLFGVLHNIEQHSSSNQMTAFNLAVCVA 514
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS 120
P++L S S E + + KV L++FLI+NC IFGE I S ++
Sbjct: 515 PSILW--PPASSSPELENEFTKKVSLLIQFLIENCLRIFGEEITSLFREVSVRCDTRENA 572
Query: 121 SDVSTLQ-NDSAYDSNDPDVESN 142
SD+S Q NDS+YDS + ++ +
Sbjct: 573 SDISCFQLNDSSYDSLENELNED 595
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 63.9 bits (154), Expect = 4e-10
Identities = 54/228 (23%), Positives = 95/228 (41%), Gaps = 27/228 (11%)
Query: 6 MQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLT 65
+QD++ +++ L + KLP N + ++L+ L +++ S+VN+M SN+AI +GPN+L
Sbjct: 350 VQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLW 409
Query: 66 LENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPV---------------HSSIT 110
N+ +L+ E + V ++E +I + F E + HS T
Sbjct: 410 ARNEGTLA-EMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHT 468
Query: 111 SDDS----LEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQ-------PQVPMA 159
+DS LE + ++ ++ D + P + S+ + +P R P A
Sbjct: 469 GNDSDSGTLERKRPASMAVMEGDLVKKESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQA 528
Query: 160 TAAGLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQ 207
A + Q P P A K + A P P P Q
Sbjct: 529 AAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQ 576
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 62.8 bits (151), Expect = 8e-10
Identities = 78/298 (26%), Positives = 128/298 (42%), Gaps = 30/298 (10%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
M A +++ R++AL++V +LP NL L++L+ L +++ EVN+M SN+AI +G
Sbjct: 369 MRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLG 428
Query: 61 PNML---TLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVH-SSITSDDSLE 116
PN+L E DQ+ +A + +V +VE LI + +F +I + S + S +L+
Sbjct: 429 PNLLWPPEKEGDQA-QLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGLFSAVTLQ 487
Query: 117 HTDSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVS 176
T S +++ S + + + +P+ P +A+AA + + EV
Sbjct: 488 DTVSDRLAS----EELPSTAVPTPATTPAPAPAPAPAPAPALASAATKE----RTESEVP 539
Query: 177 PEPIVSTVARLKSSLAQP----DRRY-----SEPSMPSSQ-ECLESRVTNQTLTKSEGDF 226
P P V R A P RR + P+MP Q S L G
Sbjct: 540 PRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSP 599
Query: 227 PVPR------VGSRLESEEAEDPF-PEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRAL 277
P+ VGS L + P P PA + + P + P S P +L
Sbjct: 600 GTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSL 657
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 62.0 bits (149), Expect = 1e-09
Identities = 78/339 (23%), Positives = 133/339 (39%), Gaps = 53/339 (15%)
Query: 6 MQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLT 65
+QD++ +++ L + KLP N + ++L+ L +++ S+VN+M SN+AI +GPN+L
Sbjct: 350 VQDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLW 409
Query: 66 LENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPV---------------HSSIT 110
N+ +L+ E + V ++E +I + F E + HS T
Sbjct: 410 ARNEGTLA-EMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHSFHT 468
Query: 111 SDDS----LEHTDSSDVSTLQND----SAYDSNDPDVESNSSSGI-----SSPSRQPQVP 157
+DS LE + ++ ++ D ++ D +++ G SP+ QP +P
Sbjct: 469 GNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQPPLP 528
Query: 158 MATAAGLDSAG----PQDAREVSPE---PIVSTVARLKSSLAQPDRRYSEPSMPSSQECL 210
+ + AG PQ +R S + S+ L+ + D +P P S
Sbjct: 529 PTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVP 588
Query: 211 ESRVTNQTLTKSEGDFPVPRVGSRL----ESEEAEDPFPEEVFPAVQGKTKRPVDLKIKN 266
N + + P GS + A P P + AV K P K N
Sbjct: 589 APGRNNSQIASGQNQ-PQAAAGSHQLSMGQPHNAAGPSPHTLRRAV--KKPAPAPPKPGN 645
Query: 267 LAPGSVLPRALVLKAFSSSSLDASSDSSPVASPSSPKRN 305
PG S +S P SP P R+
Sbjct: 646 PPPGHP----------GGQSSSGTSQHPPSLSPKPPTRS 674
>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
Length = 439
Score = 56.2 bits (134), Expect = 8e-08
Identities = 33/92 (35%), Positives = 53/92 (57%), Gaps = 5/92 (5%)
Query: 8 DEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLE 67
DE R+ A QV LP N +L+ L L IS +S+ N+M ++NLA+ GPN+L +
Sbjct: 345 DESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAK 404
Query: 68 NDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIF 99
D +++ +A N + T +FL+D+ E+F
Sbjct: 405 -DAAITLKA----INPINTFTKFLLDHQGELF 431
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 55.8 bits (133), Expect = 1e-07
Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 14/156 (8%)
Query: 3 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 62
A ++ D E ++ ALK+V K P+ N + K+++ L+ +S N++VN M S NL+IC P
Sbjct: 1344 AHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPT 1403
Query: 63 MLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSD 122
++ + + A + +T++E I C F N P+ + S +S
Sbjct: 1404 LMRPDFSTMDALTATR----TYQTIIELFIQQC-PFFFYNRPITEPPGARPSSPSAVAST 1458
Query: 123 VSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPM 158
V L + P SP PQ PM
Sbjct: 1459 VPFLTSTPVTSQPSPP---------QSPPPTPQSPM 1485
>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
[Homo sapiens]
Length = 1075
Score = 53.9 bits (128), Expect = 4e-07
Identities = 24/88 (27%), Positives = 53/88 (60%), Gaps = 1/88 (1%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
+ +++++ +R+ ++Q+ LPR ++++++L L+ +S+ S+ N MD NLAIC G
Sbjct: 577 ISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFG 636
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLV 88
P ++ + + Q Q +N +KT++
Sbjct: 637 PTLMHIPDGQD-PVSCQAHINEVIKTII 663
>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
[Homo sapiens]
Length = 1099
Score = 53.9 bits (128), Expect = 4e-07
Identities = 24/88 (27%), Positives = 53/88 (60%), Gaps = 1/88 (1%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
+ +++++ +R+ ++Q+ LPR ++++++L L+ +S+ S+ N MD NLAIC G
Sbjct: 601 ISTIKLENPAERVHQIQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFG 660
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLV 88
P ++ + + Q Q +N +KT++
Sbjct: 661 PTLMHIPDGQD-PVSCQAHINEVIKTII 687
>gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a
[Homo sapiens]
Length = 1071
Score = 53.9 bits (128), Expect = 4e-07
Identities = 85/361 (23%), Positives = 145/361 (40%), Gaps = 74/361 (20%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
M + M + ++R +++V LP+ L+++++L L+ +S+ SE N MD NLAIC G
Sbjct: 586 MACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFG 645
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLV---EFLIDNCFEIFGENIPVHSSITS-----D 112
P+++++ Q +N +KT++ E + + E+ G PV+S S D
Sbjct: 646 PSLMSVPEGHD-QVSCQAHVNELIKTIIIQHENIFPSPRELEG---PVYSRGGSMEDYCD 701
Query: 113 DSLEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDA 172
T S + ST + + ++D + E P+ A D G + A
Sbjct: 702 SPHGETTSVEDSTQDVTAEHHTSDDECE----------------PIEAIAKFDYVG-RTA 744
Query: 173 REVSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQ-TLTKSEGDFPVPRV 231
RE+S + S + +R S+ ++ + +Q + + D V R
Sbjct: 745 RELSFKKGASLLLY---------QRASDDWWEGRHNGIDGLIPHQYIVVQDTEDGVVERS 795
Query: 232 GSRLESEEAEDPFPEEVFPAVQGKT----KRPVDLKIKNLAPGSVLPRA-LVLKAF---- 282
+ E E +P PEE A G + D+ + N+ P + + K F
Sbjct: 796 SPKSEIEVISEP-PEEKVTARAGASCPSGGHVADIYLANINKQRKRPESGSIRKTFRSDS 854
Query: 283 ---SSSSLDASS---------DSSPVASPSSPKR-------------NFFSRHQSFTTKT 317
SSS D+SS S P+ S S PK N SRH S +
Sbjct: 855 HGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGSLNSISRHSSLKNRL 914
Query: 318 E 318
+
Sbjct: 915 D 915
>gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b
[Homo sapiens]
Length = 836
Score = 52.8 bits (125), Expect = 8e-07
Identities = 38/143 (26%), Positives = 65/143 (45%), Gaps = 23/143 (16%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
M + M + ++R +++V LP+ L+++++L L+ +S+ SE N MD NLAIC G
Sbjct: 586 MACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFG 645
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLV---------------------EFLIDNCFEIF 99
P+++++ Q +N +KT++ + D C
Sbjct: 646 PSLMSVPEGHD-QVSCQAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPH 704
Query: 100 GENIPVHSSITSDDSLEHTDSSD 122
GE V S T D + EH S D
Sbjct: 705 GETTSVEDS-TQDVTAEHHTSDD 726
>gi|156071465 Rho GTPase activating protein 4 [Homo sapiens]
Length = 946
Score = 51.6 bits (122), Expect = 2e-06
Identities = 35/141 (24%), Positives = 71/141 (50%), Gaps = 6/141 (4%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
+ + E++ +R+E + ++ +LP P L++L++L L+ +++ S+ N MD NLA+C G
Sbjct: 602 LASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFG 661
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDS 120
P +L + Q L +V LV+ LI +F + + + + +
Sbjct: 662 PTLLPVPAGQD-----PVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPV-YEKCMAPPSA 715
Query: 121 SDVSTLQNDSAYDSNDPDVES 141
S + Q +S N+P++E+
Sbjct: 716 SCLGDAQLESLGADNEPELEA 736
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 50.8 bits (120), Expect = 3e-06
Identities = 25/92 (27%), Positives = 58/92 (63%), Gaps = 1/92 (1%)
Query: 3 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 62
A +Q+++ +++AL +KLP+ N +++L+ L +S+ +VN+M SN+AI +GPN
Sbjct: 350 ASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPN 409
Query: 63 MLTLENDQSLSFEAQKDLNNKVKTLVEFLIDN 94
+L + + +++ E ++ ++ ++E +I +
Sbjct: 410 LLWPQAEGNIT-EMMTTVSLQIVGIIEPIIQH 440
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/243 (25%), Positives = 105/243 (43%), Gaps = 33/243 (13%)
Query: 3 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 62
A +++++E R+ + + +LP N +L+ L+ L ++ N + N M +NL + GP
Sbjct: 476 AAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPT 535
Query: 63 MLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFG-------ENIPVH-SSITSDDS 114
+L + + + K N ++E LI+N +IF N +H S S DS
Sbjct: 536 LLRPQEETVAAIMDIKFQN----IVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDS 591
Query: 115 -----------LEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGI-SSPSRQPQVPMATAA 162
L HT S Q +S +S+ V SN +S + SS S QP + ++
Sbjct: 592 KPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNM---NSS 648
Query: 163 GLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRRYSEPS--MPSSQECLESRVTNQTLT 220
D A + R S P S + L S +S PS MP+S +S +
Sbjct: 649 DPDLAVVKPTRPNSLPPNPSPTSPLSPSWPM----FSAPSSPMPTSSTSSDSSPVSTPFR 704
Query: 221 KSE 223
K++
Sbjct: 705 KAK 707
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 49.7 bits (117), Expect = 7e-06
Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 19/169 (11%)
Query: 11 DRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQ 70
+R ++++ LPR L+++++L L+ +S+ S+ N MD NLAIC GP ++ + Q
Sbjct: 611 ERALHIRKLLLTLPRSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQ 670
Query: 71 SLSFEAQKDLNNKVKTLV---EFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSDVSTLQ 127
Q +N +KT++ E + + E+ G PV+ + D + S+ TL+
Sbjct: 671 D-QVSCQAHVNEIIKTIIIHHETIFPDAKELDG---PVYEKCMAGDDYCDSPYSEHGTLE 726
Query: 128 NDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVS 176
+P + P+ A D G + ARE+S
Sbjct: 727 EVDQDAGTEPHTSEDECE-----------PIEAIAKFDYVG-RSARELS 763
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 49.7 bits (117), Expect = 7e-06
Identities = 59/222 (26%), Positives = 96/222 (43%), Gaps = 31/222 (13%)
Query: 3 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 62
A +++++E R+ + + +LP N +L+ L+ L ++ N + N M +NL + GP
Sbjct: 476 AAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPT 535
Query: 63 MLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFG-------ENIPVH-SSITSDDS 114
+L + + + K N ++E LI+N +IF N +H S S DS
Sbjct: 536 LLRPQEETVAAIMDIKFQN----IVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDS 591
Query: 115 -----------LEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGI-SSPSRQPQVPMATAA 162
L HT S Q +S +S+ V SN +S + SS S QP + ++
Sbjct: 592 KPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNM---NSS 648
Query: 163 GLDSAGPQDAREVSPEPIVSTVARLKSSLAQPDRRYSEPSMP 204
D A + R S P S + L S +S PS P
Sbjct: 649 DPDLAVVKPTRPNSLPPNPSPTSPLSPSWPM----FSAPSSP 686
>gi|7382480 Rho GTPase activating protein 6 isoform 4 [Homo sapiens]
Length = 771
Score = 49.3 bits (116), Expect = 9e-06
Identities = 105/446 (23%), Positives = 161/446 (36%), Gaps = 69/446 (15%)
Query: 8 DEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVN-----------RMDSSNLA 56
+ E+++ L+ + LP N L L+ L +++++++ N +M S NLA
Sbjct: 293 EPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLA 352
Query: 57 ICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSD--DS 114
GPN+L + F Q + T + ++ E + V + ++ S
Sbjct: 353 TIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLIS 412
Query: 115 LEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDARE 174
L TD V L A S+ PD+ S S R +T + S+G +
Sbjct: 413 LLETDPDVVDYLLRRKASQSSSPDM-LQSEVSFSVGGRH----SSTDSNKASSG-----D 462
Query: 175 VSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTL-------TKSEGDFP 227
+SP S V +S LA E + P E L RV Q + +KS P
Sbjct: 463 ISPYDNNSPVLSERSLLAM-----QEDAAPGGSEKL-YRVPGQFMLVGHLSSSKSRESSP 516
Query: 228 VPRVGSRLESEEAEDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSL 287
PR+G L +E+PF +++ LK + PG + F SSSL
Sbjct: 517 GPRLGKDL----SEEPF--DIWGTWHS------TLKSGSKDPGMTGSSGDI---FESSSL 561
Query: 288 DAS--SDSSPVASPSSPKRNFFSRHQSFTT----KTEKGKPSREIKKHS--MSFTFAPHK 339
A S S SP+ P+ T +T+ P+ E + H PH
Sbjct: 562 RAGPCSLSQGNLSPNWPRWQGSPAELDSDTQGARRTQAAAPATEGRAHPAVSRACSTPHV 621
Query: 340 KVLTKNLSAGSGKSQDFTRDHVPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALS 399
+V K + Q T E +AG A C RPH
Sbjct: 622 QVAGKAERPTARSEQYLTLSGAHDLSESELDVAGL----------QSRATPQCQRPHGSG 671
Query: 400 VDDVFQGADWERPGSPPSYEEAMQGP 425
DD + PG P + +QGP
Sbjct: 672 RDDKRPPPPYPGPGKPAAAAAWIQGP 697
>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
sapiens]
Length = 974
Score = 49.3 bits (116), Expect = 9e-06
Identities = 105/446 (23%), Positives = 161/446 (36%), Gaps = 69/446 (15%)
Query: 8 DEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVN-----------RMDSSNLA 56
+ E+++ L+ + LP N L L+ L +++++++ N +M S NLA
Sbjct: 496 EPEEQLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHADDNISKDGQEVTGNKMTSLNLA 555
Query: 57 ICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSD--DS 114
GPN+L + F Q + T + ++ E + V + ++ S
Sbjct: 556 TIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLIS 615
Query: 115 LEHTDSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDARE 174
L TD V L A S+ PD+ S S R +T + S+G +
Sbjct: 616 LLETDPDVVDYLLRRKASQSSSPDM-LQSEVSFSVGGRH----SSTDSNKASSG-----D 665
Query: 175 VSPEPIVSTVARLKSSLAQPDRRYSEPSMPSSQECLESRVTNQTL-------TKSEGDFP 227
+SP S V +S LA E + P E L RV Q + +KS P
Sbjct: 666 ISPYDNNSPVLSERSLLAM-----QEDAAPGGSEKL-YRVPGQFMLVGHLSSSKSRESSP 719
Query: 228 VPRVGSRLESEEAEDPFPEEVFPAVQGKTKRPVDLKIKNLAPGSVLPRALVLKAFSSSSL 287
PR+G L +E+PF +++ LK + PG + F SSSL
Sbjct: 720 GPRLGKDL----SEEPF--DIWGTWHS------TLKSGSKDPGMTGSSGDI---FESSSL 764
Query: 288 DAS--SDSSPVASPSSPKRNFFSRHQSFTT----KTEKGKPSREIKKHS--MSFTFAPHK 339
A S S SP+ P+ T +T+ P+ E + H PH
Sbjct: 765 RAGPCSLSQGNLSPNWPRWQGSPAELDSDTQGARRTQAAAPATEGRAHPAVSRACSTPHV 824
Query: 340 KVLTKNLSAGSGKSQDFTRDHVPRGVRKESQLAGRIVQENGCETHNQTARGFCLRPHALS 399
+V K + Q T E +AG A C RPH
Sbjct: 825 QVAGKAERPTARSEQYLTLSGAHDLSESELDVAGL----------QSRATPQCQRPHGSG 874
Query: 400 VDDVFQGADWERPGSPPSYEEAMQGP 425
DD + PG P + +QGP
Sbjct: 875 RDDKRPPPPYPGPGKPAAAAAWIQGP 900
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 49.3 bits (116), Expect = 9e-06
Identities = 49/203 (24%), Positives = 92/203 (45%), Gaps = 19/203 (9%)
Query: 7 QDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNML-T 65
+D DR++ LK++ LP + LK L L +++NSE N+M+ NLAI GP ++ T
Sbjct: 1250 EDPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRT 1309
Query: 66 LENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSDVST 125
E++ + D V+TL++ D F G P+ +++ + +++ ++
Sbjct: 1310 SEDNMTHMVTHMPDQYKIVETLIQH-HDWFFTEEGAEEPL-TTVQEESTVDSQPVPNIDH 1367
Query: 126 LQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVSTVA 185
L + P S+S++ S+ S+ S Q +RE+ I + +
Sbjct: 1368 LLTNIGRTGVSPGDVSDSATSDSTKSK---------GSWGSGKDQYSRELLVSSIFAAAS 1418
Query: 186 RLKSSLAQPDRRYSEPSMPSSQE 208
R + ++ E + PSS E
Sbjct: 1419 RKR-------KKPKEKAQPSSSE 1434
>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
Length = 555
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 12 RIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQS 71
R+ +Q+ LP N ++L++L+ LH +S+ S N+M+SSNLA G N++ S
Sbjct: 421 RVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS 480
Query: 72 LSFEAQKDLNNKVKTLVEF 90
S A LN + L+E+
Sbjct: 481 -SLSALVPLNMFTELLIEY 498
>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
sapiens]
Length = 433
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 12 RIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQS 71
R+ +Q+ LP N ++L++L+ LH +S+ S N+M+SSNLA G N++ S
Sbjct: 299 RVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS 358
Query: 72 LSFEAQKDLNNKVKTLVEF 90
S A LN + L+E+
Sbjct: 359 -SLSALVPLNMFTELLIEY 376
>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
sapiens]
Length = 464
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 12 RIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQS 71
R+ +Q+ LP N ++L++L+ LH +S+ S N+M+SSNLA G N++ S
Sbjct: 330 RVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS 389
Query: 72 LSFEAQKDLNNKVKTLVEF 90
S A LN + L+E+
Sbjct: 390 -SLSALVPLNMFTELLIEY 407
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 47.0 bits (110), Expect = 5e-05
Identities = 26/67 (38%), Positives = 36/67 (53%)
Query: 3 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 62
A++ QD RIEA+K + KLP PN +K L L I + N M + +L I GP
Sbjct: 378 AIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPT 437
Query: 63 MLTLEND 69
+L EN+
Sbjct: 438 LLRAENE 444
>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
sapiens]
Length = 874
Score = 45.8 bits (107), Expect = 1e-04
Identities = 74/312 (23%), Positives = 123/312 (39%), Gaps = 34/312 (10%)
Query: 3 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 62
A++ D+ R+EA+ + KLP N +L L+ L +S +S+ N M SNL + GP
Sbjct: 480 AVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPT 539
Query: 63 MLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIF----GENIPVHSSITSDDSLEHT 118
++ + + + K N +VE LI++ +IF +IP+ + S T
Sbjct: 540 LMRAQEETVAAMMNIKFQN----IVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGS-RRT 594
Query: 119 DSSDVSTLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPE 178
+ +ST E +S S SSP P ++S + + S
Sbjct: 595 RAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPM------GSIESLSSHSSEQNSTT 648
Query: 179 PIVSTVARLKSS----LAQPDRRYSEPSMPSSQECLESRVTNQTLTKSEGDFPVPRVGSR 234
S R KS +A P + S+ ES + + TK++ + V S
Sbjct: 649 KSASCQPREKSGGIPWIATPSSSNGQKSLGLWTTSPESS-SREDATKTDAESDCQSVASV 707
Query: 235 LESEEAEDPFPEEVFPAVQGKTKRPVDLK-IKNLAPGSV--LPRALVLKAFS---SSSLD 288
P +V P + K P L +K + S+ + A K++S S
Sbjct: 708 TS--------PGDVSPPIDLVKKEPYGLSGLKRASASSLRSISAAEGNKSYSGSIQSLTS 759
Query: 289 ASSDSSPVASPS 300
S +P ASP+
Sbjct: 760 VGSKETPKASPN 771
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 4/99 (4%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
+ A+++QD+ R ++ + LP PN L+ L L + ++ E NRM ++AI G
Sbjct: 424 IAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFG 483
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIF 99
P +L E +++ S N+V VE ++ C +IF
Sbjct: 484 PTLLRPEVEET-SMPMTMVFQNQV---VELILQQCADIF 518
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 45.8 bits (107), Expect = 1e-04
Identities = 29/99 (29%), Positives = 51/99 (51%), Gaps = 4/99 (4%)
Query: 1 MGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIG 60
+ A+++QD+ R ++ + LP PN L+ L L + ++ E NRM ++AI G
Sbjct: 451 IAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFG 510
Query: 61 PNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIF 99
P +L E +++ S N+V VE ++ C +IF
Sbjct: 511 PTLLRPEVEET-SMPMTMVFQNQV---VELILQQCADIF 545
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 45.8 bits (107), Expect = 1e-04
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 13/191 (6%)
Query: 4 LEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNM 63
L + E +E KQV++ LP+ N LL+++ L + S VN+M NLA GPN+
Sbjct: 258 LTKDEGEGTLELAKQVSN-LPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNI 316
Query: 64 LTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITSDDSLEHTDSSDV 123
L + + ++ L V+ L+ LI ++F +P + L+
Sbjct: 317 LRPQVEDPVTIMEGTSL---VQHLMTVLIRKHSQLFTAPVP-EGPTSPRGGLQCAVGWGS 372
Query: 124 STLQNDSAYDSNDPDVESNSSSGISSPSRQPQVPMATAAGLDSAGPQDAREVSPEPIVST 183
+ DS + P + ++ +S + + +A + GP SP V T
Sbjct: 373 EEVTRDSQGEPGGPGLPAHRTSSLDGAA------VAVLSRTAPTGP--GSRCSPGKKVQT 424
Query: 184 VARLKSSLAQP 194
+ KSS QP
Sbjct: 425 LPSWKSSFRQP 435
>gi|206597515 ArfGAP with RhoGAP domain, ankyrin repeat and PH
domain 1 isoform d [Homo sapiens]
Length = 1133
Score = 45.4 bits (106), Expect = 1e-04
Identities = 26/91 (28%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Query: 3 ALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPN 62
A E++DEE+++ +++ +LP N +K L+ L+ + S+ N+M+ NLAI GP
Sbjct: 748 ASEIEDEEEKVSRYRELLVRLPPVNRATVKALISHLYCVQCFSDTNQMNVHNLAIVFGPT 807
Query: 63 MLTLENDQSLSFEAQKDLNNKVKTLVEFLID 93
+ + + +DL N +V F +D
Sbjct: 808 LFQTDGQDYKAGRVVEDLINHY--VVVFSVD 836
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,112,036
Number of Sequences: 37866
Number of extensions: 1172191
Number of successful extensions: 4690
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 137
Number of HSP's that attempted gapping in prelim test: 4148
Number of HSP's gapped (non-prelim): 457
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.