Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 231569458
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo
sapiens]
(629 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens] 1308 0.0
gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens] 1266 0.0
gi|4557759 myeloperoxidase [Homo sapiens] 702 0.0
gi|4503595 eosinophil peroxidase [Homo sapiens] 693 0.0
gi|28558982 thyroid peroxidase isoform a [Homo sapiens] 533 e-151
gi|28558988 thyroid peroxidase isoform d [Homo sapiens] 533 e-151
gi|109150416 peroxidasin [Homo sapiens] 449 e-126
gi|28558984 thyroid peroxidase isoform b [Homo sapiens] 446 e-125
gi|126517478 peroxidasin homolog-like [Homo sapiens] 395 e-110
gi|28558990 thyroid peroxidase isoform e [Homo sapiens] 291 2e-78
gi|20149640 dual oxidase 1 precursor [Homo sapiens] 121 2e-27
gi|28872751 dual oxidase 1 precursor [Homo sapiens] 121 2e-27
gi|132566532 dual oxidase 2 precursor [Homo sapiens] 119 8e-27
gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1 prec... 50 8e-06
gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo... 47 7e-05
gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2 prec... 42 0.002
gi|224451032 KIAA1683 isoform a [Homo sapiens] 30 8.8
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 30 8.8
gi|224451036 KIAA1683 isoform c [Homo sapiens] 30 8.8
gi|54606862 KIAA1683 isoform b [Homo sapiens] 30 8.8
>gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]
Length = 629
Score = 1308 bits (3384), Expect = 0.0
Identities = 629/629 (100%), Positives = 629/629 (100%)
Query: 1 MRVLLHLPALLASLILLQAAASTTRDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITG 60
MRVLLHLPALLASLILLQAAASTTRDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITG
Sbjct: 1 MRVLLHLPALLASLILLQAAASTTRDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITG 60
Query: 61 DCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYL 120
DCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYL
Sbjct: 61 DCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYL 120
Query: 121 NEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPP 180
NEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPP
Sbjct: 121 NEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPP 180
Query: 181 NDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNL 240
NDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNL
Sbjct: 181 NDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNL 240
Query: 241 SSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSH 300
SSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSH
Sbjct: 241 SSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSH 300
Query: 301 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 360
TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP
Sbjct: 301 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 360
Query: 361 PYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRM 420
PYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRM
Sbjct: 361 PYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRM 420
Query: 421 VKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQ 480
VKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQ
Sbjct: 421 VKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQ 480
Query: 481 PGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGR 540
PGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGR
Sbjct: 481 PGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGR 540
Query: 541 VGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDP 600
VGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDP
Sbjct: 541 VGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDP 600
Query: 601 FWANSYPYDFVDCSAIDKLDLSPWASVKN 629
FWANSYPYDFVDCSAIDKLDLSPWASVKN
Sbjct: 601 FWANSYPYDFVDCSAIDKLDLSPWASVKN 629
>gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]
Length = 712
Score = 1266 bits (3276), Expect = 0.0
Identities = 605/612 (98%), Positives = 608/612 (99%)
Query: 18 QAAASTTRDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRAL 77
+A+ + DPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRAL
Sbjct: 101 KASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRAL 160
Query: 78 ARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQW 137
ARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQW
Sbjct: 161 ARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQW 220
Query: 138 GQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRA 197
GQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRA
Sbjct: 221 GQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRA 280
Query: 198 GFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHG 257
GFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHG
Sbjct: 281 GFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHG 340
Query: 258 LPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRL 317
LPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRL
Sbjct: 341 LPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRL 400
Query: 318 NPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF 377
NPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF
Sbjct: 401 NPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF 460
Query: 378 TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKK 437
TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKK
Sbjct: 461 TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKK 520
Query: 438 SKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQT 497
SKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQT
Sbjct: 521 SKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQT 580
Query: 498 LEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIR 557
LEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIR
Sbjct: 581 LEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIR 640
Query: 558 DGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAID 617
DGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAID
Sbjct: 641 DGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAID 700
Query: 618 KLDLSPWASVKN 629
KLDLSPWASVKN
Sbjct: 701 KLDLSPWASVKN 712
Score = 48.9 bits (115), Expect = 1e-05
Identities = 26/35 (74%), Positives = 30/35 (85%)
Query: 1 MRVLLHLPALLASLILLQAAASTTRDPSLDLTSLS 35
MRVLLHLPALLASLILLQAAASTTR + +++S
Sbjct: 1 MRVLLHLPALLASLILLQAAASTTRAQTTRTSAIS 35
>gi|4557759 myeloperoxidase [Homo sapiens]
Length = 745
Score = 702 bits (1812), Expect = 0.0
Identities = 337/597 (56%), Positives = 434/597 (72%), Gaps = 7/597 (1%)
Query: 31 LTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLS 90
L LS GC V C YRTITG CNNRR P LGA+NRA RWLPAEYEDG S
Sbjct: 149 LNVLSKSSGCAYQDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFS 208
Query: 91 LPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPD 150
LP+GWTPG RNGFP+ LAR VSN+IV + ++ DQ RSL+FMQWGQ++DHDLDF P+
Sbjct: 209 LPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPE 268
Query: 151 TELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLA 210
+S + C+ C+Q CFP+ PPNDP+ Q C+PFFR+ CP P ++
Sbjct: 269 PAARASFVTGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRS---CPACPGSNIT 325
Query: 211 -REQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPS 269
R QINALTSF+DAS VY SE LA LRN+S+ LGL+AVNQ D+G LP+D+
Sbjct: 326 IRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDD 385
Query: 270 PCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQE 329
PC N +AR+PCFLAGD+R+SE L + HTL LREHNRLA ELK LNP+WDGE+LYQE
Sbjct: 386 PCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQE 445
Query: 330 ARKILGAFVQIITFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEV 388
ARKI+GA VQIIT+RDYLP++LG M+K++P Y+ Y++SVDPRI+NVFT AFR+GH +
Sbjct: 446 ARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLI 505
Query: 389 PSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMT 448
MFRLD YQP P P +PL +FF +WR+V +GGIDP++RGL+A +KL +QN++
Sbjct: 506 QPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAV 565
Query: 449 GELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSK 508
E+R +LF+ RI G DL A+N QR RDHG PGYN+WR FC L QP+T+ +L TVL++
Sbjct: 566 DEIRERLFEQVMRI-GLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNL 624
Query: 509 MLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPG 568
LA+KL+ YGTP+NIDIW+G ++EPL +GRVGPLLAC++G QF+++RDGDRFWWEN G
Sbjct: 625 KLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEG 684
Query: 569 VFTNEQKDSLQKMSFSRLVCDNTRITKVPRDP-FWANSYPYDFVDCSAIDKLDLSPW 624
VF+ +Q+ +L ++S R++CDNT IT V ++ F +NSYP DFV+CS + L+L+ W
Sbjct: 685 VFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASW 741
>gi|4503595 eosinophil peroxidase [Homo sapiens]
Length = 715
Score = 693 bits (1789), Expect = 0.0
Identities = 341/600 (56%), Positives = 432/600 (72%), Gaps = 8/600 (1%)
Query: 26 DPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEY 85
+P L L LS GC RC YRTITG CNN+R+P LGA+N+ALARWLPAEY
Sbjct: 120 EPQLRL--LSQASGCALRDQAERCS--DKYRTITGRCNNKRRPLLGASNQALARWLPAEY 175
Query: 86 EDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDL 145
EDGLSLPFGWTP + RNGF LPL R VSN+IV + NE D+ R+L+FMQWGQ +DHDL
Sbjct: 176 EDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFPNERLTSDRGRALMFMQWGQFIDHDL 235
Query: 146 DFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPP 205
DF+P++ + + C+ C Q CFPI PPNDP+ Q C+PFFR+ CP
Sbjct: 236 DFSPESPARVAFTAGVDCERTCAQLPPCFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQN- 294
Query: 206 YKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDS 265
K+ R QINALTSF+DAS VY SE SL+ RLRN ++ LGL+A+NQ D+G LP+D+
Sbjct: 295 -KNRVRNQINALTSFVDASMVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDN 353
Query: 266 KKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEK 325
PC N +AR+PCFLAGD+R++E LA HTLF+REHNRLA EL+RLNP+W+G+K
Sbjct: 354 LHDDPCLLTNRSARIPCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDK 413
Query: 326 LYQEARKILGAFVQIITFRDYLPILLGD-HMQKWIPPYQGYSESVDPRISNVFTFAFRFG 384
LY EARKI+GA VQIIT+RD+LP++LG ++ + Y+GY +VDPR++NVFT AFRFG
Sbjct: 414 LYNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFG 473
Query: 385 HLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQN 444
H + MFRLD Y+ P +PL + FF +WR+V +GGIDP++RGL+A +KL +Q+
Sbjct: 474 HTMLQPFMFRLDSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQD 533
Query: 445 KMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTV 504
M+ ELR++LF+ RI G DLAA+N QR RDHG PGYN+WR FC LSQP+ L +L+ V
Sbjct: 534 AMLVDELRDRLFRQVRRI-GLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRV 592
Query: 505 LKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWW 564
LK++ LA+K L LYGTPDNIDIWIGAIAEPL+ RVGPLLACL QF++ RDGDRFWW
Sbjct: 593 LKNQDLARKFLNLYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWW 652
Query: 565 ENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
+ GVFT Q+ +L ++S SR++CDNT IT V RD F AN YP FV+CS I +L+LS W
Sbjct: 653 QKRGVFTKRQRKALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAW 712
>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
Length = 933
Score = 533 bits (1373), Expect = e-151
Identities = 279/585 (47%), Positives = 364/585 (62%), Gaps = 18/585 (3%)
Query: 55 YRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSN 114
YR ITG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+
Sbjct: 151 YRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTR 210
Query: 115 KIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCF 174
++ NE D S L M WGQ +DHD+ F P + ++ A C C + CF
Sbjct: 211 HVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCF 270
Query: 175 PIMFPPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASF 225
PI P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS
Sbjct: 271 PIQLPEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 226 VYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVP 281
VY S P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R P
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
Query: 282 CFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQII 341
CFLAGD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QII
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 342 TFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENY 399
T RDY+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 400 QPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPT 459
Q P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +LF +
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Query: 460 HRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYG 519
+ DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L LY
Sbjct: 569 NS-STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 627
Query: 520 TPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQ 579
PDNID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+
Sbjct: 628 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 687
Query: 580 KMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
K S SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 688 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 732
>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
Length = 889
Score = 533 bits (1373), Expect = e-151
Identities = 279/585 (47%), Positives = 364/585 (62%), Gaps = 18/585 (3%)
Query: 55 YRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSN 114
YR ITG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+
Sbjct: 151 YRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTR 210
Query: 115 KIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCF 174
++ NE D S L M WGQ +DHD+ F P + ++ A C C + CF
Sbjct: 211 HVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCF 270
Query: 175 PIMFPPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASF 225
PI P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS
Sbjct: 271 PIQLPEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 226 VYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVP 281
VY S P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R P
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
Query: 282 CFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQII 341
CFLAGD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QII
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 342 TFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENY 399
T RDY+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 400 QPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPT 459
Q P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +LF +
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Query: 460 HRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYG 519
+ DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L LY
Sbjct: 569 NS-STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 627
Query: 520 TPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQ 579
PDNID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+
Sbjct: 628 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 687
Query: 580 KMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
K S SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 688 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 732
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 449 bits (1155), Expect = e-126
Identities = 250/597 (41%), Positives = 349/597 (58%), Gaps = 17/597 (2%)
Query: 39 GCGAPAPVVRC-DPC--SPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGW 95
GC A V C D C YRT G CNN + P GA+ A R L + YE+G + P G
Sbjct: 722 GCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGI 781
Query: 96 TPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGS 155
P + NG LP+ R VS ++G E D+ + + MQWGQ +DHDLD + L
Sbjct: 782 NPHRLYNGHALPMPRLVSTTLIG--TETVTPDEQFTHMLMQWGQFLDHDLD-STVVALSQ 838
Query: 156 SEYSKAQ-CDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLA---- 210
+ +S Q C C CF +M PPND +A + +CM F R+ VC + L
Sbjct: 839 ARFSDGQHCSNVCSNDPPCFSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLLMNSVY 898
Query: 211 -REQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPS 269
REQIN LTS++DAS VY S A +R+L+S GL+ V G P LP+ + P+
Sbjct: 899 PREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGI-VQRSGKPLLPFATGPPT 957
Query: 270 PCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQE 329
C + +PCFLAGD RA+E + L + HTL+ REHNR+A EL +LNP WDG+ +Y E
Sbjct: 958 ECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYE 1017
Query: 330 ARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEV 388
RKI+GA +Q IT++ +LP +LG+ + + Y GY ++ I N F T AFRFGH V
Sbjct: 1018 TRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLV 1077
Query: 389 PSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMT 448
++RLDEN+QP + LPLH FF+ +R+V +GGIDPL+RGL K+ ++++
Sbjct: 1078 NPLLYRLDENFQPIAQD-HLPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLN 1136
Query: 449 GELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSK 508
EL +LF H + DLAAIN QR RDHG P Y+ +R +C+LS T E+L +K+
Sbjct: 1137 TELTERLFSMAHTV-ALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNP 1195
Query: 509 MLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPG 568
+ +KL LYG+ NID++ + E LV R+GP L CLL QF+++RDGDR W+ENPG
Sbjct: 1196 EIREKLKRLYGSTLNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPG 1255
Query: 569 VFTNEQKDSLQKMSFSRLVCDNT-RITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
VF+ Q +++ S +R++CDN IT+V D F +P+ + C I ++DL W
Sbjct: 1256 VFSPAQLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVW 1312
>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
Length = 876
Score = 446 bits (1146), Expect = e-125
Identities = 250/585 (42%), Positives = 322/585 (55%), Gaps = 75/585 (12%)
Query: 55 YRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSN 114
YR ITG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+
Sbjct: 151 YRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTR 210
Query: 115 KIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCF 174
++ NE D S L M WGQ +DHD+ F P + ++ A C C + CF
Sbjct: 211 HVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCF 270
Query: 175 PIMFPPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASF 225
PI P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS
Sbjct: 271 PIQLPEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 226 VYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVP 281
VY S P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R P
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
Query: 282 CFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQII 341
CFLAGD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QII
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 342 TFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENY 399
T RDY+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 400 QPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPT 459
Q P+LP W L F P
Sbjct: 509 QE---HPDLP------GLW--------------------------------LHQAFFSPW 527
Query: 460 HRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYG 519
+ G GYN WR FC L + +T +L+T + S+ +A K+L LY
Sbjct: 528 TLLRG-----------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 570
Query: 520 TPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQ 579
PDNID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+
Sbjct: 571 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 630
Query: 580 KMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
K S SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 631 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 675
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 395 bits (1015), Expect = e-110
Identities = 240/598 (40%), Positives = 330/598 (55%), Gaps = 22/598 (3%)
Query: 39 GCGAPAPVVRC-DPC--SPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGW 95
GC A P+ C + C + YR G CNN ++P GAA A AR L Y DG+ P G
Sbjct: 708 GCTARRPLPNCSNRCFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGL 767
Query: 96 -TPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELG 154
P +R PLP R V+ V D + + + M WG ++HDLD L
Sbjct: 768 GLPVGSRQ--PLPPPRLVAT--VWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPA-LS 822
Query: 155 SSEYSKAQ-CDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVC----PTPPYKSL 209
++ +S + C C CFP+ DP+ GT CM F R+ C P+ S+
Sbjct: 823 TARFSDGRPCSSVCTNDPPCFPMNTRHADPR-GTHAPCMLFARSSPACASGRPSATVDSV 881
Query: 210 -AREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP 268
AREQIN T+++D S VY S + LR+ S P GL+ G P LP+ + P
Sbjct: 882 YAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPP 941
Query: 269 SPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQ 328
+ C PCFLAGD RA+EH+ LA HTL+ REHNR+A EL LNP W+G +YQ
Sbjct: 942 TECA--RQEQESPCFLAGDHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQ 999
Query: 329 EARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLE 387
EARKI+GA +Q IT+ +LP +LGD + + Y+GY+ +V+ I N F T AFRFGH
Sbjct: 1000 EARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTL 1059
Query: 388 VPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMM 447
+ ++RL+ E LP H F+ R++K+GGIDP++RGL +K + ++
Sbjct: 1060 INPILYRLNATLGEIS-EGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLL 1118
Query: 448 TGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKS 507
+ EL +LF + D AA QR RDHG P Y +R FC+L+ + E+L +K
Sbjct: 1119 SPELTQRLFSAAYSA-AVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKD 1177
Query: 508 KMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENP 567
+ +KL LYG+P +ID+W + E L+ RVGP L CL QFQ++RDGDRFW+ENP
Sbjct: 1178 SEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENP 1237
Query: 568 GVFTNEQKDSLQKMSFSRLVCDN-TRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
GVFT Q L++ S SR++CDN I +V D F YP D+++CS I K+DL W
Sbjct: 1238 GVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVW 1295
>gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
Length = 760
Score = 291 bits (744), Expect = 2e-78
Identities = 139/289 (48%), Positives = 195/289 (67%), Gaps = 3/289 (1%)
Query: 338 VQIITFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRL 395
+QIIT RDY+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RL
Sbjct: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331
Query: 396 DENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKL 455
D ++Q P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +L
Sbjct: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391
Query: 456 FQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLL 515
F ++ DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L
Sbjct: 392 FVLSNS-STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKIL 450
Query: 516 GLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQK 575
LY PDNID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+
Sbjct: 451 DLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQR 510
Query: 576 DSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
L+K S SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 511 RELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 559
Score = 121 bits (304), Expect = 2e-27
Identities = 60/122 (49%), Positives = 70/122 (57%)
Query: 55 YRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSN 114
YR ITG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+
Sbjct: 151 YRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTR 210
Query: 115 KIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCF 174
++ NE D S L M WGQ +DHD+ F P + ++ A C C + CF
Sbjct: 211 HVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCF 270
Query: 175 PI 176
PI
Sbjct: 271 PI 272
>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 121 bits (304), Expect = 2e-27
Identities = 148/565 (26%), Positives = 245/565 (43%), Gaps = 71/565 (12%)
Query: 41 GAPAPVVRCDPCS-PYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGK 99
GA P+ +P S + G NN + G+ L R +PA Y DG+ P G
Sbjct: 14 GAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH-- 71
Query: 100 TRNGFPLPLAREVSNKIVGYLNEEGVLD-QNRSLLFMQWGQIVDHDLDFAPDTELGSSEY 158
LP R++SN I G+ +NR++L + +G V DL + +T +E+
Sbjct: 72 ------LPNPRDLSNTISR--GPAGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPAEF 122
Query: 159 SKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFFRAGFVCPTPPYKSLAREQIN 215
I PP DP + +PF R+ + T S R+ N
Sbjct: 123 LN---------------IRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPAN 167
Query: 216 ALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP-----SP 270
+T +LD S +Y S S + LR+ S G +A + P P DS+ P +P
Sbjct: 168 QVTGWLDGSAIYGSSHSWSDALRSFSR--GQLASGPD------PAFPRDSQNPLLMWAAP 219
Query: 271 CEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEA 330
+ G R + L L+ R HN A+ L R +P W+ E+L+Q A
Sbjct: 220 DPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHA 279
Query: 331 RKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAF-RFGHLEVP 389
RK + A Q I ++LP L QK +P Y GY +DP IS+ F A +F VP
Sbjct: 280 RKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVP 335
Query: 390 SSMFRLDENYQPWG---PEPELPLHTLFFNTW------RMVKDGGIDPLVRGLLAKKSKL 440
++ + + G + N++ + +D L+ G+ ++ ++
Sbjct: 336 PGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE- 394
Query: 441 MKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEE 500
+++ ++ ++R+ P + D A QR RD G P Y RA LS ++
Sbjct: 395 -REDHVLVEDVRDFWPGPL-KFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQD 452
Query: 501 LNTVL--KSKMLAKKLLGLYGTPDNIDI-WIGAIAEPLVERGR-VGPLLACLLGKQFQQI 556
+N L + + + LY N D+ W+ + L+E R GPL + ++ +QF ++
Sbjct: 453 INPALSRSNDTVLEATAALY----NQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRL 508
Query: 557 RDGDRFWWENP--GVFTNEQKDSLQ 579
RDGDR+W+EN G+F+ ++ + ++
Sbjct: 509 RDGDRYWFENTRNGLFSKKEIEEIR 533
>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 121 bits (304), Expect = 2e-27
Identities = 148/565 (26%), Positives = 245/565 (43%), Gaps = 71/565 (12%)
Query: 41 GAPAPVVRCDPCS-PYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGK 99
GA P+ +P S + G NN + G+ L R +PA Y DG+ P G
Sbjct: 14 GAWTPLGAQNPISWEVQRFDGWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPH-- 71
Query: 100 TRNGFPLPLAREVSNKIVGYLNEEGVLD-QNRSLLFMQWGQIVDHDLDFAPDTELGSSEY 158
LP R++SN I G+ +NR++L + +G V DL + +T +E+
Sbjct: 72 ------LPNPRDLSNTISR--GPAGLASLRNRTVLGVFFGYHVLSDL-VSVETPGCPAEF 122
Query: 159 SKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK---CMPFFRAGFVCPTPPYKSLAREQIN 215
I PP DP + +PF R+ + T S R+ N
Sbjct: 123 LN---------------IRIPPGDPMFDPDQRGDVVLPFQRSRWDPETGRSPSNPRDPAN 167
Query: 216 ALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP-----SP 270
+T +LD S +Y S S + LR+ S G +A + P P DS+ P +P
Sbjct: 168 QVTGWLDGSAIYGSSHSWSDALRSFSR--GQLASGPD------PAFPRDSQNPLLMWAAP 219
Query: 271 CEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEA 330
+ G R + L L+ R HN A+ L R +P W+ E+L+Q A
Sbjct: 220 DPATGQNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHA 279
Query: 331 RKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAF-RFGHLEVP 389
RK + A Q I ++LP L QK +P Y GY +DP IS+ F A +F VP
Sbjct: 280 RKRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVP 335
Query: 390 SSMFRLDENYQPWG---PEPELPLHTLFFNTW------RMVKDGGIDPLVRGLLAKKSKL 440
++ + + G + N++ + +D L+ G+ ++ ++
Sbjct: 336 PGVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAE- 394
Query: 441 MKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEE 500
+++ ++ ++R+ P + D A QR RD G P Y RA LS ++
Sbjct: 395 -REDHVLVEDVRDFWPGPL-KFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQD 452
Query: 501 LNTVL--KSKMLAKKLLGLYGTPDNIDI-WIGAIAEPLVERGR-VGPLLACLLGKQFQQI 556
+N L + + + LY N D+ W+ + L+E R GPL + ++ +QF ++
Sbjct: 453 INPALSRSNDTVLEATAALY----NQDLSWLELLPGGLLESHRDPGPLFSTIVLEQFVRL 508
Query: 557 RDGDRFWWENP--GVFTNEQKDSLQ 579
RDGDR+W+EN G+F+ ++ + ++
Sbjct: 509 RDGDRYWFENTRNGLFSKKEIEEIR 533
>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
Length = 1548
Score = 119 bits (298), Expect = 8e-27
Identities = 154/594 (25%), Positives = 250/594 (42%), Gaps = 92/594 (15%)
Query: 13 SLILLQAAASTTRDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGA 72
+L+LL A + + PS + +LSL P V R D G NN R GA
Sbjct: 8 ALMLLGALLTGSLGPSGNQDALSL------PWEVQRYD---------GWFNNLRHHERGA 52
Query: 73 ANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSL 132
L R +PA Y DG+ + LP R +SN + L NR++
Sbjct: 53 VGCRLQRRVPANYADGVY--------QALEEPQLPNPRRLSNAATRGIAGLPSL-HNRTV 103
Query: 133 LFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGK-- 190
L + +G V D+ + +T +E+ I PP DP +
Sbjct: 104 LGVFFGYHVLSDV-VSVETPGCPAEFLN---------------IRIPPGDPVFDPDQRGD 147
Query: 191 -CMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAV 249
+PF R+ + T S R+ N +T +LD S +Y S S + LR+ S G +A
Sbjct: 148 VVLPFQRSRWDPETGRSPSNPRDLANQVTGWLDGSAIYGSSHSWSDALRSFSG--GQLAS 205
Query: 250 NQEVSDHGLPYLPYDSKKP-----SPCEFINTTARVPCFLAGDSRASEHILLATSHTLFL 304
+ P P DS+ P +P + G R + L L+
Sbjct: 206 GPD------PAFPRDSQNPLLMWAAPDPATGQNGPRGLYAFGAERGNREPFLQALGLLWF 259
Query: 305 REHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQG 364
R HN A+ L R +P W+ E+L+Q ARK + A Q I ++LP L QK +P Y G
Sbjct: 260 RYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL----QKTLPEYTG 315
Query: 365 YSESVDPRISNVFTFAF-RFGHLEVPSSMFR----------LDENYQPWGPEPELPLHTL 413
Y +DP IS F A +F VP ++ L++ +Q +
Sbjct: 316 YRPFLDPSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQ------SSQALRV 369
Query: 414 FFNTW-----RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLA 468
N W + ++ L+ G+ ++ S+L ++ ++ +LR+ P + D
Sbjct: 370 CNNYWIRENPNLNSTQEVNELLLGMASQISEL--EDNIVVEDLRDYWPGP-GKFSRTDYV 426
Query: 469 AINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTP-DNIDIW 527
A + QR RD G P Y+ L P+ +LN + ++L + LY +++
Sbjct: 427 ASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDLNPNVDPQVL-EATAALYNQDLSQLELL 485
Query: 528 IGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENP--GVFTNEQKDSLQ 579
+G + E G GPL + ++ QF ++RDGDR+W+EN G+F+ ++ + ++
Sbjct: 486 LGGLLE---SHGDPGPLFSAIVLDQFVRLRDGDRYWFENTRNGLFSKKEIEDIR 536
>gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1
precursor [Homo sapiens]
Length = 599
Score = 49.7 bits (117), Expect = 8e-06
Identities = 75/305 (24%), Positives = 120/305 (39%), Gaps = 47/305 (15%)
Query: 301 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 360
TL+LREHNR+ LK +P W E+L+Q R IL I +Y+ L G +Q
Sbjct: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361
Query: 361 P--YQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTW 418
P G RI+ F + + H +P S F++ E FNT
Sbjct: 362 PELLFGVQFQYRNRIAMEFNHLYHW-HPLMPDS-FKVGSQ--------EYSYEQFLFNT- 410
Query: 419 RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDH 478
M+ D G++ LV ++ + G + H +H +A + R+
Sbjct: 411 SMLVDYGVEALVDAF----------SRQIAGRIGGGRNMDHHILH---VAVDVIRESREM 457
Query: 479 GQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAI------- 531
+N +R + + +EL + K +A +L LYG D ++ + G +
Sbjct: 458 RLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPN 514
Query: 532 ---AEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQK-MSFSRLV 587
E ++E G L LLG +W P F E ++ K + +LV
Sbjct: 515 SIFGESMIEIGAPFSLKG-LLGNPI----CSPEYW--KPSTFGGEVGFNIVKTATLKKLV 567
Query: 588 CDNTR 592
C NT+
Sbjct: 568 CLNTK 572
>gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo
sapiens]
Length = 604
Score = 46.6 bits (109), Expect = 7e-05
Identities = 24/61 (39%), Positives = 35/61 (57%)
Query: 301 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 360
T++LREHNR+ LK+ +P+W E+L+Q +R IL I DY+ L G H +
Sbjct: 289 TIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFD 348
Query: 361 P 361
P
Sbjct: 349 P 349
>gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2
precursor [Homo sapiens]
Length = 562
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/61 (39%), Positives = 32/61 (52%)
Query: 301 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 360
TL+LREHNR+ LK +P W E+L+Q R IL I +Y+ L G +Q
Sbjct: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361
Query: 361 P 361
P
Sbjct: 362 P 362
>gi|224451032 KIAA1683 isoform a [Homo sapiens]
Length = 1367
Score = 29.6 bits (65), Expect = 8.8
Identities = 15/38 (39%), Positives = 16/38 (42%)
Query: 80 WLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIV 117
W E P G PGKT G P P A EV +V
Sbjct: 796 WAKPEDRQTQPQPHGHVPGKTTQGGPCPAACEVQGMLV 833
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 29.6 bits (65), Expect = 8.8
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 1/48 (2%)
Query: 51 PCSPYRTITGDCNNR-RKPALGAANRALARWLPAEYEDGLSLPFGWTP 97
P + YR CN+ K A+N AR +PAE D + P W P
Sbjct: 795 PFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEP 842
>gi|224451036 KIAA1683 isoform c [Homo sapiens]
Length = 1134
Score = 29.6 bits (65), Expect = 8.8
Identities = 15/38 (39%), Positives = 16/38 (42%)
Query: 80 WLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIV 117
W E P G PGKT G P P A EV +V
Sbjct: 750 WAKPEDRQTQPQPHGHVPGKTTQGGPCPAACEVQGMLV 787
>gi|54606862 KIAA1683 isoform b [Homo sapiens]
Length = 1180
Score = 29.6 bits (65), Expect = 8.8
Identities = 15/38 (39%), Positives = 16/38 (42%)
Query: 80 WLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIV 117
W E P G PGKT G P P A EV +V
Sbjct: 796 WAKPEDRQTQPQPHGHVPGKTTQGGPCPAACEVQGMLV 833
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,039,462
Number of Sequences: 37866
Number of extensions: 1230270
Number of successful extensions: 2609
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2523
Number of HSP's gapped (non-prelim): 36
length of query: 629
length of database: 18,247,518
effective HSP length: 108
effective length of query: 521
effective length of database: 14,157,990
effective search space: 7376312790
effective search space used: 7376312790
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.