Guide to the Human Genome
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Search of human proteins with 23110960

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
         (334 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23110960 cathepsin L2 preproprotein [Homo sapiens]                 704   0.0  
gi|22202619 cathepsin L1 preproprotein [Homo sapiens]                 552   e-157
gi|4503155 cathepsin L1 preproprotein [Homo sapiens]                  552   e-157
gi|4503151 cathepsin K preproprotein [Homo sapiens]                   333   1e-91
gi|23110962 cathepsin S preproprotein [Homo sapiens]                  329   2e-90
gi|23110957 cathepsin H isoform b precursor [Homo sapiens]            229   3e-60
gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]        229   3e-60
gi|6042196 cathepsin F [Homo sapiens]                                 179   3e-45
gi|4557501 cathepsin O preproprotein [Homo sapiens]                   141   9e-34
gi|23110964 cathepsin W preproprotein [Homo sapiens]                  129   4e-30
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]       124   1e-28
gi|239744067 PREDICTED: similar to Putative cathepsin L-like pro...   117   1e-26
gi|22538437 cathepsin B preproprotein [Homo sapiens]                   98   1e-20
gi|22538435 cathepsin B preproprotein [Homo sapiens]                   98   1e-20
gi|22538433 cathepsin B preproprotein [Homo sapiens]                   98   1e-20
gi|22538431 cathepsin B preproprotein [Homo sapiens]                   98   1e-20
gi|4503139 cathepsin B preproprotein [Homo sapiens]                    98   1e-20
gi|22538442 cathepsin Z preproprotein [Homo sapiens]                   94   2e-19
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]       90   2e-18
gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa...    82   5e-16
gi|169189860 PREDICTED: similar to Cathepsin L1 [Homo sapiens]         74   1e-13
gi|46049092 nebulin-related anchoring protein isoform C [Homo sa...    30   3.0  
gi|46049105 nebulin-related anchoring protein isoform S [Homo sa...    30   3.0  
gi|149944640 zinc finger and BTB domain containing 34 [Homo sapi...    30   3.0  
gi|51093381 leptin receptor isoform 3 [Homo sapiens]                   29   6.7  
gi|31442420 shroom family member 1 [Homo sapiens]                      29   6.7  
gi|109637798 RAD52 homolog [Homo sapiens]                              28   8.8  
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]             28   8.8  

>gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
          Length = 334

 Score =  704 bits (1818), Expect = 0.0
 Identities = 334/334 (100%), Positives = 334/334 (100%)

Query: 1   MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60
           MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
Sbjct: 1   MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60

Query: 61  LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120
           LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
Sbjct: 61  LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120

Query: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180
           RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
Sbjct: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180

Query: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240
           GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
Sbjct: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240

Query: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300
           ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
Sbjct: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300

Query: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
           NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
Sbjct: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334


>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  552 bits (1423), Expect = e-157
 Identities = 259/334 (77%), Positives = 291/334 (87%), Gaps = 1/334 (0%)

Query: 1   MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60
           MN +L+LAAFCLGIASA   FD +L+ +W +WKA H RLYG NEEGWRRAVWEKNMKMIE
Sbjct: 1   MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60

Query: 61  LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120
           LHN EY +GKH FTMAMNAFGDMT+EEFRQ+M  F+N+K RKGKVF+EPLF + P+SVDW
Sbjct: 61  LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120

Query: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180
           R+KGYVTPVKNQ QCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQGN+GCNG
Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180

Query: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240
           G M  AFQYV++NGGLDSEESYPY A +E CKY P+ SVANDTGF V  P +EKALMKAV
Sbjct: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGF-VDIPKQEKALMKAV 239

Query: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300
           ATVGPISVA+DAGH SF FYK GIYFEPDCSS+++DHGVLVVGYGFE   S+N+KYWLVK
Sbjct: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299

Query: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
           NSWG EWG  GYVK+AKD+ NHCGIA+AASYP V
Sbjct: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333


>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  552 bits (1423), Expect = e-157
 Identities = 259/334 (77%), Positives = 291/334 (87%), Gaps = 1/334 (0%)

Query: 1   MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60
           MN +L+LAAFCLGIASA   FD +L+ +W +WKA H RLYG NEEGWRRAVWEKNMKMIE
Sbjct: 1   MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60

Query: 61  LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120
           LHN EY +GKH FTMAMNAFGDMT+EEFRQ+M  F+N+K RKGKVF+EPLF + P+SVDW
Sbjct: 61  LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120

Query: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180
           R+KGYVTPVKNQ QCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQGN+GCNG
Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180

Query: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240
           G M  AFQYV++NGGLDSEESYPY A +E CKY P+ SVANDTGF V  P +EKALMKAV
Sbjct: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGF-VDIPKQEKALMKAV 239

Query: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300
           ATVGPISVA+DAGH SF FYK GIYFEPDCSS+++DHGVLVVGYGFE   S+N+KYWLVK
Sbjct: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299

Query: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
           NSWG EWG  GYVK+AKD+ NHCGIA+AASYP V
Sbjct: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333


>gi|4503151 cathepsin K preproprotein [Homo sapiens]
          Length = 329

 Score =  333 bits (854), Expect = 1e-91
 Identities = 164/319 (51%), Positives = 213/319 (66%), Gaps = 14/319 (4%)

Query: 22  DQNLDTKWYQWKATHRRLYGAN-EEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAF 80
           ++ LDT W  WK THR+ Y    +E  RR +WEKN+K I +HN E S G H + +AMN  
Sbjct: 19  EEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHL 78

Query: 81  GDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLD-----LPKSVDWRKKGYVTPVKNQKQC 135
           GDMT+EE  Q M   +           + L++       P SVD+RKKGYVTPVKNQ QC
Sbjct: 79  GDMTSEEVVQKMTGLKVPLSHSRS--NDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQC 136

Query: 136 GSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGG 195
           GSCWAFS+ GALEGQ+ +KTGKL++LS QNLVDC     N GC GG+M  AFQYV++N G
Sbjct: 137 GSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRG 194

Query: 196 LDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHS 255
           +DSE++YPYV  +E C Y P    A   G+  +  G EKAL +AVA VGP+SVA+DA  +
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLT 254

Query: 256 SFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKI 315
           SFQFY  G+Y++  C+S NL+H VL VGYG +  N    K+W++KNSWG  WG+ GY+ +
Sbjct: 255 SFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGN----KHWIIKNSWGENWGNKGYILM 310

Query: 316 AKDKNNHCGIATAASYPNV 334
           A++KNN CGIA  AS+P +
Sbjct: 311 ARNKNNACGIANLASFPKM 329


>gi|23110962 cathepsin S preproprotein [Homo sapiens]
          Length = 331

 Score =  329 bits (843), Expect = 2e-90
 Identities = 166/333 (49%), Positives = 222/333 (66%), Gaps = 10/333 (3%)

Query: 7   LAAFCLGIASAVPKF--DQNLDTKWYQWKATHRRLYGA-NEEGWRRAVWEKNMKMIELHN 63
           L    L  +SAV +   D  LD  W+ WK T+ + Y   NEE  RR +WEKN+K + LHN
Sbjct: 4   LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63

Query: 64  GEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFR-NQKFRKGKVFREPLFLDLPKSVDWRK 122
            E+S G H + + MN  GDMT+EE   +M   R   ++++   ++      LP SVDWR+
Sbjct: 64  LEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWRE 123

Query: 123 KGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQGCNGG 181
           KG VT VK Q  CG+CWAFSA GALE Q+  KTGKLVSLS QNLVDCS  + GN+GCNGG
Sbjct: 124 KGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGG 183

Query: 182 FMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVA 241
           FM  AFQY+ +N G+DS+ SYPY A+D+ C+Y  +   A  + +T +  G+E  L +AVA
Sbjct: 184 FMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVA 243

Query: 242 TVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKN 301
             GP+SV +DA H SF  Y+SG+Y+EP C ++N++HGVLVVGYG    + N  +YWLVKN
Sbjct: 244 NKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKN 298

Query: 302 SWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
           SWG  +G  GY+++A++K NHCGIA+  SYP +
Sbjct: 299 SWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331


>gi|23110957 cathepsin H isoform b precursor [Homo sapiens]
          Length = 323

 Score =  229 bits (583), Expect = 3e-60
 Identities = 124/304 (40%), Positives = 166/304 (54%), Gaps = 13/304 (4%)

Query: 32  WKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQM 91
           W + HR+ Y   E   R   +  N + I  HN     G H F MA+N F DM+  E +  
Sbjct: 26  WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSFAEIKHK 81

Query: 92  MGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKG-YVTPVKNQKQCGSCWAFSATGALEGQ 150
                 Q     K          P SVDWRKKG +V+PVKNQ  CGSCW FS TGALE  
Sbjct: 82  YLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESA 141

Query: 151 MFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI 210
           +   TGK++SL+EQ LVDC++   N GC GG  ++AF+Y+  N G+  E++YPY   D  
Sbjct: 142 IAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGY 201

Query: 211 CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDC 270
           CK++P  ++        +    E+A+++AVA   P+S A +     F  Y++GIY    C
Sbjct: 202 CKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSC 260

Query: 271 --SSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATA 328
             +   ++H VL VGYG      N   YW+VKNSWGP+WG NGY  I + K N CG+A  
Sbjct: 261 HKTPDKVNHAVLAVGYG----EKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAAC 315

Query: 329 ASYP 332
           ASYP
Sbjct: 316 ASYP 319


>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
          Length = 335

 Score =  229 bits (583), Expect = 3e-60
 Identities = 124/304 (40%), Positives = 166/304 (54%), Gaps = 13/304 (4%)

Query: 32  WKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQM 91
           W + HR+ Y   E   R   +  N + I  HN     G H F MA+N F DM+  E +  
Sbjct: 38  WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSFAEIKHK 93

Query: 92  MGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKG-YVTPVKNQKQCGSCWAFSATGALEGQ 150
                 Q     K          P SVDWRKKG +V+PVKNQ  CGSCW FS TGALE  
Sbjct: 94  YLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESA 153

Query: 151 MFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI 210
           +   TGK++SL+EQ LVDC++   N GC GG  ++AF+Y+  N G+  E++YPY   D  
Sbjct: 154 IAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGY 213

Query: 211 CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDC 270
           CK++P  ++        +    E+A+++AVA   P+S A +     F  Y++GIY    C
Sbjct: 214 CKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSC 272

Query: 271 --SSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATA 328
             +   ++H VL VGYG      N   YW+VKNSWGP+WG NGY  I + K N CG+A  
Sbjct: 273 HKTPDKVNHAVLAVGYG----EKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAAC 327

Query: 329 ASYP 332
           ASYP
Sbjct: 328 ASYP 331


>gi|6042196 cathepsin F [Homo sapiens]
          Length = 484

 Score =  179 bits (454), Expect = 3e-45
 Identities = 120/309 (38%), Positives = 164/309 (53%), Gaps = 35/309 (11%)

Query: 35  THRRLYGANEEG-WRRAVWEKNM----KMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFR 89
           T+ R Y + EE  WR +V+  NM    K+  L  G    G       +  F D+T EEFR
Sbjct: 193 TYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYG-------VTKFSDLTEEEFR 245

Query: 90  QMMGCFRNQKFRK---GKVFREPLFLDL-PKSVDWRKKGYVTPVKNQKQCGSCWAFSATG 145
            +   + N   RK    K+ +     DL P   DWR KG VT VK+Q  CGSCWAFS TG
Sbjct: 246 TI---YLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTG 302

Query: 146 ALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYV 205
            +EGQ F   G L+SLSEQ L+DC +   ++ C GG  + A+  +K  GGL++E+ Y Y 
Sbjct: 303 NVEGQWFLNQGTLLSLSEQELLDCDKM--DKACMGGLPSNAYSAIKNLGGLETEDDYSYQ 360

Query: 206 AVDEICKYRPENS--VANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSG 263
              + C +  E +    ND   +V     E+ L   +A  GPISVA++A     QFY+ G
Sbjct: 361 GHMQSCNFSAEKAKVYIND---SVELSQNEQKLAAWLAKRGPISVAINA--FGMQFYRHG 415

Query: 264 IY--FEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNN 321
           I     P CS   +DH VL+VGYG    N ++  +W +KNSWG +WG  GY  + +  + 
Sbjct: 416 ISRPLRPLCSPWLIDHAVLLVGYG----NRSDVPFWAIKNSWGTDWGEKGYYYLHRG-SG 470

Query: 322 HCGIATAAS 330
            CG+ T AS
Sbjct: 471 ACGVNTMAS 479


>gi|4557501 cathepsin O preproprotein [Homo sapiens]
          Length = 321

 Score =  141 bits (355), Expect = 9e-34
 Identities = 93/263 (35%), Positives = 134/263 (50%), Gaps = 23/263 (8%)

Query: 77  MNAFGDMTNEEFRQMMGCFRNQKFRK--GKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQ 134
           +N F  +  EEF+ +    +  KF +   +V      + LP   DWR K  VT V+NQ+ 
Sbjct: 69  INQFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQM 128

Query: 135 CGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYV-KEN 193
           CG CWAFS  GA+E     K   L  LS Q ++DCS    N GCNGG    A  ++ K  
Sbjct: 129 CGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCS--YNNYGCNGGSTLNALNWLNKMQ 186

Query: 194 GGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVA------PGKEKALMKAVATVGPIS 247
             L  +  YP+ A + +C Y       + +GF++          +E  + KA+ T GP+ 
Sbjct: 187 VKLVKDSEYPFKAQNGLCHY----FSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLV 242

Query: 248 VAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEW 307
           V +DA   S+Q Y  GI  +  CSS   +H VL+ G+   G    ++ YW+V+NSWG  W
Sbjct: 243 VIVDA--VSWQDYLGGI-IQHHCSSGEANHAVLITGFDKTG----STPYWIVRNSWGSSW 295

Query: 308 GSNGYVKIAKDKNNHCGIATAAS 330
           G +GY  + K  +N CGIA + S
Sbjct: 296 GVDGYAHV-KMGSNVCGIADSVS 317


>gi|23110964 cathepsin W preproprotein [Homo sapiens]
          Length = 376

 Score =  129 bits (324), Expect = 4e-30
 Identities = 91/270 (33%), Positives = 132/270 (48%), Gaps = 30/270 (11%)

Query: 80  FGDMTNEEFRQMMGCFRNQKF--RKGKVFR-EPLFLDLPKSVDWRK-KGYVTPVKNQKQC 135
           F D+T EEF Q+ G  R        G+  R E     +P S DWRK  G ++P+K+QK C
Sbjct: 91  FSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNC 150

Query: 136 GSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGG 195
             CWA +A G +E          V +S Q L+DC R     GC+GGF+  AF  V  N G
Sbjct: 151 NCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRC--GDGCHGGFVWDAFITVLNNSG 208

Query: 196 LDSEESYPYVAVDEICKYRPEN--SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAG 253
           L SE+ YP+       +  P+    VA    F ++    E  + + +AT GPI+V ++  
Sbjct: 209 LASEKDYPFQGKVRAHRCHPKKYQKVAWIQDF-IMLQNNEHRIAQYLATYGPITVTINM- 266

Query: 254 HSSFQFYKSGIY--FEPDCSSKNLDHGVLVVGYGF---------EGANSNN-------SK 295
               Q Y+ G+       C  + +DH VL+VG+G          E  +S +       + 
Sbjct: 267 -KPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTP 325

Query: 296 YWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
           YW++KNSWG +WG  GY ++ +  N  CGI
Sbjct: 326 YWILKNSWGAQWGEKGYFRLHRGSNT-CGI 354


>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
          Length = 463

 Score =  124 bits (311), Expect = 1e-28
 Identities = 83/232 (35%), Positives = 119/232 (51%), Gaps = 20/232 (8%)

Query: 112 LDLPKSVDWRKK---GYVTPVKNQKQCGSCWAFSATGALEGQM--FRKTGKLVSLSEQNL 166
           L LP S DWR      +V+PV+NQ  CGSC++F++ G LE ++       +   LS Q +
Sbjct: 229 LHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEV 288

Query: 167 VDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFT 226
           V CS  Q  QGC GGF         ++ GL  E  +PY   D  CK + +      + + 
Sbjct: 289 VSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYH 346

Query: 227 VVAP---GKEKALMKA-VATVGPISVAMDAGHSSFQFYKSGIYF-----EPDCSSKNLDH 277
            V     G  +ALMK  +   GP++VA +  +  F  YK GIY      +P    +  +H
Sbjct: 347 YVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGLRDPFNPFELTNH 405

Query: 278 GVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAA 329
            VL+VGYG + A+  +  YW+VKNSWG  WG NGY +I +   + C I + A
Sbjct: 406 AVLLVGYGTDSASGMD--YWIVKNSWGTGWGENGYFRIRRG-TDECAIESIA 454


>gi|239744067 PREDICTED: similar to Putative cathepsin L-like
           protein 6 [Homo sapiens]
          Length = 81

 Score =  117 bits (293), Expect = 1e-26
 Identities = 55/77 (71%), Positives = 62/77 (80%)

Query: 56  MKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLP 115
           MKM E HN EYSQGKH FTMAMN FGDMT EEFRQ+M  F+ QK R GK F+E L L++P
Sbjct: 1   MKMTEQHNQEYSQGKHSFTMAMNTFGDMTTEEFRQVMNGFQYQKHRNGKQFQERLLLEIP 60

Query: 116 KSVDWRKKGYVTPVKNQ 132
            SVDWR+KGYVTPVK+Q
Sbjct: 61  TSVDWREKGYVTPVKDQ 77


>gi|22538437 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%)

Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165
           L LP S D    W +   +  +++Q  CGSCWAF A  A+  ++   T   VS+  S ++
Sbjct: 78  LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137

Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206
           L+ C       GCNGG+ A A+ +    G +     ES+    PY               
Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197

Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254
                      +IC+  Y P        G+   +    EK +M  +   GP+  A    +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256

Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314
           S F  YKSG+Y           H + ++G+G E    N + YWLV NSW  +WG NG+ K
Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311

Query: 315 IAKDKNNHCGI 325
           I + + +HCGI
Sbjct: 312 ILRGQ-DHCGI 321


>gi|22538435 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%)

Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165
           L LP S D    W +   +  +++Q  CGSCWAF A  A+  ++   T   VS+  S ++
Sbjct: 78  LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137

Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206
           L+ C       GCNGG+ A A+ +    G +     ES+    PY               
Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197

Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254
                      +IC+  Y P        G+   +    EK +M  +   GP+  A    +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256

Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314
           S F  YKSG+Y           H + ++G+G E    N + YWLV NSW  +WG NG+ K
Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311

Query: 315 IAKDKNNHCGI 325
           I + + +HCGI
Sbjct: 312 ILRGQ-DHCGI 321


>gi|22538433 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%)

Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165
           L LP S D    W +   +  +++Q  CGSCWAF A  A+  ++   T   VS+  S ++
Sbjct: 78  LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137

Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206
           L+ C       GCNGG+ A A+ +    G +     ES+    PY               
Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197

Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254
                      +IC+  Y P        G+   +    EK +M  +   GP+  A    +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256

Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314
           S F  YKSG+Y           H + ++G+G E    N + YWLV NSW  +WG NG+ K
Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311

Query: 315 IAKDKNNHCGI 325
           I + + +HCGI
Sbjct: 312 ILRGQ-DHCGI 321


>gi|22538431 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%)

Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165
           L LP S D    W +   +  +++Q  CGSCWAF A  A+  ++   T   VS+  S ++
Sbjct: 78  LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137

Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206
           L+ C       GCNGG+ A A+ +    G +     ES+    PY               
Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197

Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254
                      +IC+  Y P        G+   +    EK +M  +   GP+  A    +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256

Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314
           S F  YKSG+Y           H + ++G+G E    N + YWLV NSW  +WG NG+ K
Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311

Query: 315 IAKDKNNHCGI 325
           I + + +HCGI
Sbjct: 312 ILRGQ-DHCGI 321


>gi|4503139 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%)

Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165
           L LP S D    W +   +  +++Q  CGSCWAF A  A+  ++   T   VS+  S ++
Sbjct: 78  LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137

Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206
           L+ C       GCNGG+ A A+ +    G +     ES+    PY               
Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197

Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254
                      +IC+  Y P        G+   +    EK +M  +   GP+  A    +
Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256

Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314
           S F  YKSG+Y           H + ++G+G E    N + YWLV NSW  +WG NG+ K
Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311

Query: 315 IAKDKNNHCGI 325
           I + + +HCGI
Sbjct: 312 ILRGQ-DHCGI 321


>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
          Length = 303

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 74/227 (32%), Positives = 114/227 (50%), Gaps = 36/227 (15%)

Query: 113 DLPKSVDWRKK---GYVTPVKNQ---KQCGSCWAFSATGALEGQM-FRKTGKLVS--LSE 163
           DLPKS DWR      Y +  +NQ   + CGSCWA ++T A+  ++  ++ G   S  LS 
Sbjct: 61  DLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSV 120

Query: 164 QNLVDCSRPQGNQG-CNGGFMARAFQYVKENGGLDSEESYPYVAVDEIC----------K 212
           QN++DC    GN G C GG     + Y  ++G +  E    Y A D+ C          +
Sbjct: 121 QNVIDC----GNAGSCEGGNDLSVWDYAHQHG-IPDETCNNYQAKDQECDKFNQCGTCNE 175

Query: 213 YRPENSVANDTGFTV----VAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEP 268
           ++  +++ N T + V       G+EK + +  A  GPIS  + A       Y  GIY E 
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMATERLAN-YTGGIYAEY 233

Query: 269 DCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKI 315
              +  ++H V V G+G     S+ ++YW+V+NSWG  WG  G+++I
Sbjct: 234 Q-DTTYINHVVSVAGWGI----SDGTEYWIVRNSWGEPWGERGWLRI 275


>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
          Length = 476

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 83/305 (27%), Positives = 127/305 (41%), Gaps = 61/305 (20%)

Query: 65  EYSQGKHGFTMA-MNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLD-------LPK 116
           + ++G +G+T    + F  MT E+           KFR G +   P+ L        LP 
Sbjct: 163 QVNKGDYGWTAQNYSQFWGMTLED---------GFKFRLGTLPPSPMLLSMNEMTASLPA 213

Query: 117 SVD--------WRKKGYVTPVKNQKQCGSCWAFS-ATGALEGQMFRKTGKLVS-LSEQNL 166
           + D        ++  G+     +QK C + WAFS A+ A +    +  G+  + LS QNL
Sbjct: 214 TTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNL 273

Query: 167 VDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYV----AVDEIC----------- 211
           + C   +   GCN G + RA+ Y+++ G L S   YP      A +  C           
Sbjct: 274 ISCCA-KNRHGCNSGSIDRAWWYLRKRG-LVSHACYPLFKDQNATNNGCAMASRSDGRGK 331

Query: 212 ----KYRPENSVANDTGFTVVAP----GKEKALMKAVATVGPISVAMDAGHSSFQFYKSG 263
               K  P N   ++  +    P      E  +MK +   GP+   M      F  YK+G
Sbjct: 332 RHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFH-YKTG 390

Query: 264 IYFEPDCSSKNLD-------HGVLVVGYG-FEGANSNNSKYWLVKNSWGPEWGSNGYVKI 315
           IY     ++K  +       H V + G+G   GA     K+W+  NSWG  WG NGY +I
Sbjct: 391 IYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRI 450

Query: 316 AKDKN 320
            +  N
Sbjct: 451 LRGVN 455


>gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
           sapiens]
          Length = 467

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 64/226 (28%), Positives = 92/226 (40%), Gaps = 39/226 (17%)

Query: 131 NQKQCGSCWAFSATGALEGQM-FRKTGKLVS-LSEQNLVDCSRPQGNQGCNGGFMARAFQ 188
           +Q  C   WAFS       ++     G +   LS QNL+ C   Q  QGC GG +  A+ 
Sbjct: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQ-QQGCRGGRLDGAWW 280

Query: 189 YVKENGGLDSEESYPYVAV--DEICKYRP-------------------ENSVANDTGFTV 227
           +++  G + S+  YP+     DE     P                    NS  N+     
Sbjct: 281 FLRRRGVV-SDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQ 339

Query: 228 VAP-----GKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFE-------PDCSSKNL 275
           V P       +K +MK +   GP+   M+  H  F  YK GIY         P+   ++ 
Sbjct: 340 VTPVYRLGSNDKEIMKELMENGPVQALMEV-HEDFFLYKGGIYSHTPVSLGRPERYRRHG 398

Query: 276 DHGVLVVGYGFEGANSNNS-KYWLVKNSWGPEWGSNGYVKIAKDKN 320
            H V + G+G E      + KYW   NSWGP WG  G+ +I +  N
Sbjct: 399 THSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVN 444


>gi|169189860 PREDICTED: similar to Cathepsin L1 [Homo sapiens]
          Length = 51

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 35/51 (68%), Positives = 40/51 (78%)

Query: 1  MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAV 51
          MN SL+LAAF LGIASA    D +LD +W +WKA H+RLYG NEEGWRRAV
Sbjct: 1  MNPSLLLAAFFLGIASAALTRDHSLDAQWTKWKAKHKRLYGMNEEGWRRAV 51


>gi|46049092 nebulin-related anchoring protein isoform C [Homo
           sapiens]
          Length = 1695

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 4/47 (8%)

Query: 118 VDWRKKGYVTPVKNQKQCGSCW----AFSATGALEGQMFRKTGKLVS 160
           V+W KK Y     NQ +    W     + ATG+L  +  +K G+L+S
Sbjct: 876 VEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELIS 922


>gi|46049105 nebulin-related anchoring protein isoform S [Homo
           sapiens]
          Length = 1730

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 4/47 (8%)

Query: 118 VDWRKKGYVTPVKNQKQCGSCW----AFSATGALEGQMFRKTGKLVS 160
           V+W KK Y     NQ +    W     + ATG+L  +  +K G+L+S
Sbjct: 911 VEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELIS 957


>gi|149944640 zinc finger and BTB domain containing 34 [Homo
           sapiens]
          Length = 500

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 1/54 (1%)

Query: 62  HNGEYSQGKHGFTMAMNAFGDMTNEE-FRQMMGCFRNQKFRKGKVFREPLFLDL 114
           H   YSQ     T    AFG ++N    R M+ CFR  + R+ +     L  DL
Sbjct: 281 HAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDL 334


>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
          Length = 958

 Score = 28.9 bits (63), Expect = 6.7
 Identities = 21/55 (38%), Positives = 25/55 (45%), Gaps = 3/55 (5%)

Query: 122 KKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKT--GKLVSLSEQNLVDCSRPQG 174
           KK +   V N K C      +    LEG MF K+    L+S S Q    C RPQG
Sbjct: 868 KKLFWEDVPNPKNCSWAQGLNFQKMLEGSMFVKSHHHSLIS-STQGHKHCGRPQG 921


>gi|31442420 shroom family member 1 [Homo sapiens]
          Length = 847

 Score = 28.9 bits (63), Expect = 6.7
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 3/46 (6%)

Query: 272 SKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAK 317
           S NLD G L +G  F  A+ + S    V  SWG   GS G + I +
Sbjct: 284 SMNLDSGSLKLGDAFRPASRSRSASGEVLGSWG---GSGGTIPIVQ 326


>gi|109637798 RAD52 homolog [Homo sapiens]
          Length = 418

 Score = 28.5 bits (62), Expect = 8.8
 Identities = 13/42 (30%), Positives = 24/42 (57%), Gaps = 4/42 (9%)

Query: 36  HRRLYGANE----EGWRRAVWEKNMKMIELHNGEYSQGKHGF 73
           HR +  ANE     GW  ++ ++N+  ++L+NG++  G   F
Sbjct: 69  HRVINLANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAF 110


>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
          Length = 2156

 Score = 28.5 bits (62), Expect = 8.8
 Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 16/73 (21%)

Query: 159  VSLSEQNLVDCSR-------PQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEIC 211
            V  +E ++V+CS        P  N G    F+  + +++ +  GL           D +C
Sbjct: 937  VCRNETSVVNCSNNSFSGNDPHTNSGKISNFVMESNKHITKIAGLTG---------DNLC 987

Query: 212  KYRPENSVANDTG 224
            K   ++ +ANDTG
Sbjct: 988  KEGDKSFIANDTG 1000


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,969,657
Number of Sequences: 37866
Number of extensions: 559154
Number of successful extensions: 1111
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1024
Number of HSP's gapped (non-prelim): 40
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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