Guide to the Human Genome
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Search of human proteins with 23110955

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
         (335 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]        717   0.0  
gi|23110957 cathepsin H isoform b precursor [Homo sapiens]            682   0.0  
gi|22202619 cathepsin L1 preproprotein [Homo sapiens]                 229   3e-60
gi|4503155 cathepsin L1 preproprotein [Homo sapiens]                  229   3e-60
gi|23110960 cathepsin L2 preproprotein [Homo sapiens]                 229   3e-60
gi|4503151 cathepsin K preproprotein [Homo sapiens]                   227   1e-59
gi|23110962 cathepsin S preproprotein [Homo sapiens]                  202   3e-52
gi|6042196 cathepsin F [Homo sapiens]                                 184   1e-46
gi|23110964 cathepsin W preproprotein [Homo sapiens]                  153   2e-37
gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]       148   8e-36
gi|4557501 cathepsin O preproprotein [Homo sapiens]                   147   2e-35
gi|22538437 cathepsin B preproprotein [Homo sapiens]                  112   6e-25
gi|22538435 cathepsin B preproprotein [Homo sapiens]                  112   6e-25
gi|22538433 cathepsin B preproprotein [Homo sapiens]                  112   6e-25
gi|22538431 cathepsin B preproprotein [Homo sapiens]                  112   6e-25
gi|4503139 cathepsin B preproprotein [Homo sapiens]                   112   6e-25
gi|22538442 cathepsin Z preproprotein [Homo sapiens]                   93   3e-19
gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa...    89   7e-18
gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]       84   2e-16
gi|239744067 PREDICTED: similar to Putative cathepsin L-like pro...    45   7e-05
gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens]          32   1.0  
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s...    31   1.8  
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa...    31   1.8  
gi|239756740 PREDICTED: similar to CMT1A duplicated region trans...    30   2.3  
gi|205360934 fibronectin type III domain containing 3B [Homo sap...    30   2.3  
gi|205360932 fibronectin type III domain containing 3B [Homo sap...    30   2.3  
gi|12746412 ankyrin repeat, family A (RFXANK-like), 2 [Homo sapi...    29   6.8  
gi|124286830 zinc finger protein 618 [Homo sapiens]                    28   8.8  

>gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens]
          Length = 335

 Score =  717 bits (1851), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS 60
           MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS
Sbjct: 1   MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS 60

Query: 61  NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV 120
           NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV
Sbjct: 61  NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV 120

Query: 121 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 180
           DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG
Sbjct: 121 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 180

Query: 181 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 240
           CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV
Sbjct: 181 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 240

Query: 241 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK 300
           EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK
Sbjct: 241 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK 300

Query: 301 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV 335
           NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
Sbjct: 301 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV 335


>gi|23110957 cathepsin H isoform b precursor [Homo sapiens]
          Length = 323

 Score =  682 bits (1759), Expect = 0.0
 Identities = 323/335 (96%), Positives = 323/335 (96%), Gaps = 12/335 (3%)

Query: 1   MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS 60
           MWATLPLLCA            AELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS
Sbjct: 1   MWATLPLLCA------------AELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS 48

Query: 61  NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV 120
           NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV
Sbjct: 49  NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV 108

Query: 121 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 180
           DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG
Sbjct: 109 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 168

Query: 181 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 240
           CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV
Sbjct: 169 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 228

Query: 241 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK 300
           EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK
Sbjct: 229 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK 288

Query: 301 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV 335
           NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
Sbjct: 289 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV 323


>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  229 bits (583), Expect = 3e-60
 Identities = 130/339 (38%), Positives = 188/339 (55%), Gaps = 23/339 (6%)

Query: 6   PLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKI 65
           P L   A+ LG+    +A L  +   +  +  W + H + Y   E   R   +  N + I
Sbjct: 3   PTLILAAFCLGI---ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMI 59

Query: 66  NAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPS 119
             HN     G H+F MA+N F DM+  E +   + +  QN    K    +    Y  P S
Sbjct: 60  ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLFYEAPRS 117

Query: 120 VDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNH 179
           VDWR+KG +V+PVKNQG CGSCW FS TGALE  +   TG+++SL+EQ LVDC+    N 
Sbjct: 118 VDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE 176

Query: 180 GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI-YDEEA 238
           GC GGL   AF+Y+  N G+  E++YPY+  +  CK+ P  ++    D   + I   E+A
Sbjct: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSV--ANDTGFVDIPKQEKA 234

Query: 239 MVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNG 293
           +++AVA   P+S A +   + F+ Y+ GIY    C  + + ++H VL VGYG    E + 
Sbjct: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDN 292

Query: 294 IPYWIVKNSWGPQWGMNGYFLIERG-KNMCGLAACASYP 331
             YW+VKNSWG +WGM GY  + +  +N CG+A+ ASYP
Sbjct: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331


>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score =  229 bits (583), Expect = 3e-60
 Identities = 130/339 (38%), Positives = 188/339 (55%), Gaps = 23/339 (6%)

Query: 6   PLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKI 65
           P L   A+ LG+    +A L  +   +  +  W + H + Y   E   R   +  N + I
Sbjct: 3   PTLILAAFCLGI---ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMI 59

Query: 66  NAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPS 119
             HN     G H+F MA+N F DM+  E +   + +  QN    K    +    Y  P S
Sbjct: 60  ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLFYEAPRS 117

Query: 120 VDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNH 179
           VDWR+KG +V+PVKNQG CGSCW FS TGALE  +   TG+++SL+EQ LVDC+    N 
Sbjct: 118 VDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE 176

Query: 180 GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI-YDEEA 238
           GC GGL   AF+Y+  N G+  E++YPY+  +  CK+ P  ++    D   + I   E+A
Sbjct: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSV--ANDTGFVDIPKQEKA 234

Query: 239 MVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNG 293
           +++AVA   P+S A +   + F+ Y+ GIY    C  + + ++H VL VGYG    E + 
Sbjct: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDN 292

Query: 294 IPYWIVKNSWGPQWGMNGYFLIERG-KNMCGLAACASYP 331
             YW+VKNSWG +WGM GY  + +  +N CG+A+ ASYP
Sbjct: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331


>gi|23110960 cathepsin L2 preproprotein [Homo sapiens]
          Length = 334

 Score =  229 bits (583), Expect = 3e-60
 Identities = 124/304 (40%), Positives = 166/304 (54%), Gaps = 13/304 (4%)

Query: 38  WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSFAEIKHK 93
           W + HR+ Y   E   R   +  N + I  HN     G H F MA+N F DM+  E +  
Sbjct: 32  WKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQM 91

Query: 94  YLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESA 153
                 Q     K          P SVDWRKKG +V+PVKNQ  CGSCW FS TGALE  
Sbjct: 92  MGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKG-YVTPVKNQKQCGSCWAFSATGALEGQ 150

Query: 154 IAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGY 213
           +   TGK++SL+EQ LVDC++   N GC GG  ++AF+Y+  N G+  E++YPY   D  
Sbjct: 151 MFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI 210

Query: 214 CKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSC 272
           CK++P  ++        +    E+A+++AVA   P+S A +     F  Y++GIY    C
Sbjct: 211 CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDC 270

Query: 273 HKTPDKVNHAVLAVGYG----EKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAAC 327
             +   ++H VL VGYG      N   YW+VKNSWGP+WG NGY  I + K N CG+A  
Sbjct: 271 --SSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATA 328

Query: 328 ASYP 331
           ASYP
Sbjct: 329 ASYP 332


>gi|4503151 cathepsin K preproprotein [Homo sapiens]
          Length = 329

 Score =  227 bits (579), Expect = 1e-59
 Identities = 128/309 (41%), Positives = 176/309 (56%), Gaps = 17/309 (5%)

Query: 34  HFKSWMSKHRKTYST--EEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSF 87
           H++ W   HRK Y+   +E   RL  +  N + I+ HN     G HT+++A+N   DM+ 
Sbjct: 25  HWELWKKTHRKQYNNKVDEISRRL-IWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTS 83

Query: 88  AEIKHKYLWSEPQNCSATKSNYL---RGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTF 144
            E+  K    +     +  ++ L      G  P SVD+RKKG +V+PVKNQG CGSCW F
Sbjct: 84  EEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKG-YVTPVKNQGQCGSCWAF 142

Query: 145 STTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDT 204
           S+ GALE  +   TGK+L+L+ Q LVDC  +  N GC GG  + AF+Y+  N+GI  ED 
Sbjct: 143 SSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDA 200

Query: 205 YPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVT-QDFMMYR 263
           YPY G++  C + P       +    I   +E+A+  AVA   PVS A + +   F  Y 
Sbjct: 201 YPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYS 260

Query: 264 TGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMC 322
            G+Y   SC+   D +NHAVLAVGYG + G  +WI+KNSWG  WG  GY L+ R K N C
Sbjct: 261 KGVYYDESCNS--DNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNAC 318

Query: 323 GLAACASYP 331
           G+A  AS+P
Sbjct: 319 GIANLASFP 327


>gi|23110962 cathepsin S preproprotein [Homo sapiens]
          Length = 331

 Score =  202 bits (515), Expect = 3e-52
 Identities = 119/310 (38%), Positives = 167/310 (53%), Gaps = 19/310 (6%)

Query: 34  HFKSWMSKHRKTYS--TEEYHHRLQTFASNWRKINAHN----NGNHTFKMALNQFSDMSF 87
           H+  W   + K Y    EE   RL  +  N + +  HN     G H++ + +N   DM+ 
Sbjct: 27  HWHLWKKTYGKQYKEKNEEAVRRL-IWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTS 85

Query: 88  AEIKHKYLWSEPQNCSATKSNYLRGTGP---YPPSVDWRKKGNFVSPVKNQGACGSCWTF 144
            E+    L S  +  S  + N    + P    P SVDWR+KG  V+ VK QG+CG+CW F
Sbjct: 86  EEVMS--LMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKG-CVTEVKYQGSCGACWAF 142

Query: 145 STTGALESAIAIATGKMLSLAEQQLVDCA-QDFNNHGCQGGLPSQAFEYILYNKGIMGED 203
           S  GALE+ + + TGK++SL+ Q LVDC+ + + N GC GG  + AF+YI+ NKGI  + 
Sbjct: 143 SAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA 202

Query: 204 TYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQ-DFMMY 262
           +YPY+  D  C++              +    E+ + EAVA   PVS   +     F +Y
Sbjct: 203 SYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLY 262

Query: 263 RTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NM 321
           R+G+Y   SC      VNH VL VGYG+ NG  YW+VKNSWG  +G  GY  + R K N 
Sbjct: 263 RSGVYYEPSC---TQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNH 319

Query: 322 CGLAACASYP 331
           CG+A+  SYP
Sbjct: 320 CGIASFPSYP 329


>gi|6042196 cathepsin F [Homo sapiens]
          Length = 484

 Score =  184 bits (467), Expect = 1e-46
 Identities = 111/300 (37%), Positives = 159/300 (53%), Gaps = 12/300 (4%)

Query: 35  FKSWMSKHRKTY-STEEYHHRLQTFASNW---RKINAHNNGNHTFKMALNQFSDMSFAEI 90
           FK+++  + +TY S EE   RL  F +N    +KI A + G  T +  + +FSD++  E 
Sbjct: 187 FKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRG--TAQYGVTKFSDLTEEEF 244

Query: 91  KHKYLWSEPQNCSATKSNYLRGTGPY-PPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGA 149
           +  YL +  +     K    +  G   PP  DWR KG  V+ VK+QG CGSCW FS TG 
Sbjct: 245 RTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGA-VTKVKDQGMCGSCWAFSVTGN 303

Query: 150 LESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQG 209
           +E    +  G +LSL+EQ+L+DC  D  +  C GGLPS A+  I    G+  ED Y YQG
Sbjct: 304 VEGQWFLNQGTLLSLSEQELLDC--DKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQG 361

Query: 210 KDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSS 269
               C F   KA  ++ D   ++  +E+ +   +A   P+S A         YR GI   
Sbjct: 362 HMQSCNFSAEKAKVYINDSVELS-QNEQKLAAWLAKRGPISVAINAF-GMQFYRHGISRP 419

Query: 270 TSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACAS 329
                +P  ++HAVL VGYG ++ +P+W +KNSWG  WG  GY+ + RG   CG+   AS
Sbjct: 420 LRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMAS 479


>gi|23110964 cathepsin W preproprotein [Homo sapiens]
          Length = 376

 Score =  153 bits (386), Expect = 2e-37
 Identities = 97/319 (30%), Positives = 153/319 (47%), Gaps = 35/319 (10%)

Query: 35  FKSWMSKHRKTY-STEEYHHRLQTFASNW---RKINAHNNGNHTFKMALNQFSDMSFAEI 90
           FK +  +  ++Y S EE+ HRL  FA N    +++   + G  T +  +  FSD++  E 
Sbjct: 42  FKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLG--TAEFGVTPFSDLTEEEF 99

Query: 91  KHKYLWSEPQNCSATKSNYLRGTGP---YPPSVDWRKKGNFVSPVKNQGACGSCWTFSTT 147
              Y +        +    +R   P    P S DWRK    +SP+K+Q  C  CW  +  
Sbjct: 100 GQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAA 159

Query: 148 GALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPY 207
           G +E+   I+    + ++ Q+L+DC +     GC GG    AF  +L N G+  E  YP+
Sbjct: 160 GNIETLWRISFWDFVDVSVQELLDCGRC--GDGCHGGFVWDAFITVLNNSGLASEKDYPF 217

Query: 208 QGKDGYCKFQPGK--AIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTG 265
           QGK    +  P K   + +++D   +   +E  + + +A Y P++    + +   +YR G
Sbjct: 218 QGKVRAHRCHPKKYQKVAWIQDFIMLQ-NNEHRIAQYLATYGPITVTINM-KPLQLYRKG 275

Query: 266 IYSSTSCHKTPDKVNHAVLAVGYGE---KNGI-----------------PYWIVKNSWGP 305
           +  +T     P  V+H+VL VG+G    + GI                 PYWI+KNSWG 
Sbjct: 276 VIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGA 335

Query: 306 QWGMNGYFLIERGKNMCGL 324
           QWG  GYF + RG N CG+
Sbjct: 336 QWGEKGYFRLHRGSNTCGI 354


>gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens]
          Length = 463

 Score =  148 bits (373), Expect = 8e-36
 Identities = 91/232 (39%), Positives = 126/232 (54%), Gaps = 17/232 (7%)

Query: 117 PPSVDWRKKG--NFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLS--LAEQQLVDC 172
           P S DWR     NFVSPV+NQ +CGSC++F++ G LE+ I I T    +  L+ Q++V C
Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291

Query: 173 AQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANIT 232
           +Q     GC+GG P         + G++ E  +PY G D  CK +      +  +   + 
Sbjct: 292 SQ--YAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVG 349

Query: 233 IY----DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHK--TP-DKVNHAVLA 285
            +    +E  M   +  + P++ AFEV  DF+ Y+ GIY  T       P +  NHAVL 
Sbjct: 350 GFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLL 409

Query: 286 VGYG--EKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL--AACASYPIP 333
           VGYG    +G+ YWIVKNSWG  WG NGYF I RG + C +   A A+ PIP
Sbjct: 410 VGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIP 461


>gi|4557501 cathepsin O preproprotein [Homo sapiens]
          Length = 321

 Score =  147 bits (370), Expect = 2e-35
 Identities = 90/267 (33%), Positives = 134/267 (50%), Gaps = 20/267 (7%)

Query: 72  NHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTG--PYPPSVDWRKKGNFV 129
           N T    +NQFS +   E K  YL S+P       +           P   DWR K   V
Sbjct: 62  NSTAFYGINQFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDK-QVV 120

Query: 130 SPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQA 189
           + V+NQ  CG CW FS  GA+ESA AI    +  L+ QQ++DC+  +NN+GC GG    A
Sbjct: 121 TQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCS--YNNYGCNGGSTLNA 178

Query: 190 FEYILYNK---GIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYD----EEAMVEA 242
             ++  NK    ++ +  YP++ ++G C +  G   GF   +   + YD    E+ M +A
Sbjct: 179 LNWL--NKMQVKLVKDSEYPFKAQNGLCHYFSGSHSGF--SIKGYSAYDFSDQEDEMAKA 234

Query: 243 VALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 302
           +  + P+    +    +  Y  GI      H +  + NHAVL  G+ +    PYWIV+NS
Sbjct: 235 LLTFGPLVVIVDAVS-WQDYLGGIIQH---HCSSGEANHAVLITGFDKTGSTPYWIVRNS 290

Query: 303 WGPQWGMNGYFLIERGKNMCGLAACAS 329
           WG  WG++GY  ++ G N+CG+A   S
Sbjct: 291 WGSSWGVDGYAHVKMGSNVCGIADSVS 317


>gi|22538437 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  112 bits (279), Expect = 6e-25
 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%)

Query: 91  KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128
           K    W    N      +YL+   GT   GP PP     + D +   +F           
Sbjct: 36  KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95

Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186
           +  +++QG+CGSCW F    A+   I I T   +S+  + + L+ C       GC GG P
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219
           ++A+ +    KG++    Y       PY                  +G    C    +PG
Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274
            +  + +D      + ++ + E  + A    N PV  AF V  DF++Y++G+Y     H 
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270

Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333
           T + +  HA+  +G+G +NG PYW+V NSW   WG NG+F I RG++ CG+ +     IP
Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330


>gi|22538435 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  112 bits (279), Expect = 6e-25
 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%)

Query: 91  KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128
           K    W    N      +YL+   GT   GP PP     + D +   +F           
Sbjct: 36  KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95

Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186
           +  +++QG+CGSCW F    A+   I I T   +S+  + + L+ C       GC GG P
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219
           ++A+ +    KG++    Y       PY                  +G    C    +PG
Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274
            +  + +D      + ++ + E  + A    N PV  AF V  DF++Y++G+Y     H 
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270

Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333
           T + +  HA+  +G+G +NG PYW+V NSW   WG NG+F I RG++ CG+ +     IP
Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330


>gi|22538433 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  112 bits (279), Expect = 6e-25
 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%)

Query: 91  KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128
           K    W    N      +YL+   GT   GP PP     + D +   +F           
Sbjct: 36  KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95

Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186
           +  +++QG+CGSCW F    A+   I I T   +S+  + + L+ C       GC GG P
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219
           ++A+ +    KG++    Y       PY                  +G    C    +PG
Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274
            +  + +D      + ++ + E  + A    N PV  AF V  DF++Y++G+Y     H 
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270

Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333
           T + +  HA+  +G+G +NG PYW+V NSW   WG NG+F I RG++ CG+ +     IP
Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330


>gi|22538431 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  112 bits (279), Expect = 6e-25
 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%)

Query: 91  KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128
           K    W    N      +YL+   GT   GP PP     + D +   +F           
Sbjct: 36  KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95

Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186
           +  +++QG+CGSCW F    A+   I I T   +S+  + + L+ C       GC GG P
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219
           ++A+ +    KG++    Y       PY                  +G    C    +PG
Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274
            +  + +D      + ++ + E  + A    N PV  AF V  DF++Y++G+Y     H 
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270

Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333
           T + +  HA+  +G+G +NG PYW+V NSW   WG NG+F I RG++ CG+ +     IP
Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330


>gi|4503139 cathepsin B preproprotein [Homo sapiens]
          Length = 339

 Score =  112 bits (279), Expect = 6e-25
 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%)

Query: 91  KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128
           K    W    N      +YL+   GT   GP PP     + D +   +F           
Sbjct: 36  KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95

Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186
           +  +++QG+CGSCW F    A+   I I T   +S+  + + L+ C       GC GG P
Sbjct: 96  IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155

Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219
           ++A+ +    KG++    Y       PY                  +G    C    +PG
Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214

Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274
            +  + +D      + ++ + E  + A    N PV  AF V  DF++Y++G+Y     H 
Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270

Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333
           T + +  HA+  +G+G +NG PYW+V NSW   WG NG+F I RG++ CG+ +     IP
Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330


>gi|22538442 cathepsin Z preproprotein [Homo sapiens]
          Length = 303

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 67/220 (30%), Positives = 95/220 (43%), Gaps = 28/220 (12%)

Query: 117 PPSVDWRKKG--NFVSPVKNQGA---CGSCWTFSTTGALESAIAI---ATGKMLSLAEQQ 168
           P S DWR     N+ S  +NQ     CGSCW  ++T A+   I I          L+ Q 
Sbjct: 63  PKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQN 122

Query: 169 LVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYC-KFQPGKAIGFVKD 227
           ++DC    N   C+GG     ++Y  +  GI  E    YQ KD  C KF         K+
Sbjct: 123 VIDCG---NAGSCEGGNDLSVWDYA-HQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKE 178

Query: 228 ---VANITIY---------DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKT 275
              + N T++           E M+  +    P+S     T+    Y  GIY+    ++ 
Sbjct: 179 CHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAE---YQD 235

Query: 276 PDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLI 315
              +NH V   G+G  +G  YWIV+NSWG  WG  G+  I
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275


>gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo
           sapiens]
          Length = 467

 Score = 88.6 bits (218), Expect = 7e-18
 Identities = 67/237 (28%), Positives = 100/237 (42%), Gaps = 42/237 (17%)

Query: 127 NFVSPVKNQGACGSCWTFSTTGALESAIAI-ATGKMLS-LAEQQLVDCAQDFNNHGCQGG 184
           N +    +QG C   W FST       ++I + G M   L+ Q L+ C       GC+GG
Sbjct: 215 NLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSC-DTHQQQGCRGG 273

Query: 185 LPSQAFEYILYNKGIMGEDTYPYQGKD-------------------------GYC--KFQ 217
               A+ + L  +G++ +  YP+ G++                          +C   + 
Sbjct: 274 RLDGAW-WFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYV 332

Query: 218 PGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHK-TP 276
               I  V  V  +   D+E M E +    PV    EV +DF +Y+ GIYS T      P
Sbjct: 333 NNNDIYQVTPVYRLGSNDKEIMKELME-NGPVQALMEVHEDFFLYKGGIYSHTPVSLGRP 391

Query: 277 DKVN----HAVLAVGYGEKN-----GIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 324
           ++      H+V   G+GE+       + YW   NSWGP WG  G+F I RG N C +
Sbjct: 392 ERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDI 448


>gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens]
          Length = 476

 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 69/223 (30%), Positives = 95/223 (42%), Gaps = 39/223 (17%)

Query: 134 NQGACGSCWTFSTTGALESAIAIAT-GKMLS-LAEQQLVDCAQDFNNHGCQGGLPSQAFE 191
           +Q  C + W FST       IAI + G+  + L+ Q L+ C    N HGC  G   +A+ 
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAK-NRHGCNSGSIDRAWW 294

Query: 192 YILYNKGIMGEDTYPY--------------QGKDGYCKFQPGKAIGFVKDVANITIY--- 234
           Y L  +G++    YP                  DG  K    K      + +N  IY   
Sbjct: 295 Y-LRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSN-RIYQCS 352

Query: 235 -------DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSS-TSCHKTPDKVN----HA 282
                  +E  +++ +    PV    +V +DF  Y+TGIY   TS +K  +K      HA
Sbjct: 353 PPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHA 412

Query: 283 VLAVGYGEKNGIP-----YWIVKNSWGPQWGMNGYFLIERGKN 320
           V   G+G   G       +WI  NSWG  WG NGYF I RG N
Sbjct: 413 VKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455


>gi|239744067 PREDICTED: similar to Putative cathepsin L-like
           protein 6 [Homo sapiens]
          Length = 81

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 7/71 (9%)

Query: 68  HNNGNHTFKMALNQFSDMS---FAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRK 124
           ++ G H+F MA+N F DM+   F ++ + + + + +N    +   L      P SVDWR+
Sbjct: 11  YSQGKHSFTMAMNTFGDMTTEEFRQVMNGFQYQKHRNGKQFQERLLL---EIPTSVDWRE 67

Query: 125 KGNFVSPVKNQ 135
           KG +V+PVK+Q
Sbjct: 68  KG-YVTPVKDQ 77


>gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens]
          Length = 1051

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 26/114 (22%), Positives = 42/114 (36%), Gaps = 21/114 (18%)

Query: 17  VPVCGAAELCVNSLEKFHFKSW----------------MSKHRKTYSTEEYHHRLQT--- 57
           +P+C   E CV + + F  K W                + +    Y    + + LQT   
Sbjct: 23  IPLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGILKQLNSLYLLHYFQNILQTTQG 82

Query: 58  --FASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNY 109
             F  N  +IN         K +LNQ  D +  +   + L+    +   TK+NY
Sbjct: 83  KDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKEILYWFANSTQWTKANY 136


>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
            sapiens]
          Length = 3118

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 1/82 (1%)

Query: 124  KKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQG 183
            + G F    KN   C SC+ F TT     A  +    +   AEQ ++    +   H    
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTK 1208

Query: 184  GLPSQAFEYILYNKGIMGEDTY 205
            G+  Q  E I+ +  +M ED +
Sbjct: 1209 GIVFQHPE-IVAHMDLMREDLH 1229


>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
            sapiens]
          Length = 3122

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 1/82 (1%)

Query: 124  KKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQG 183
            + G F    KN   C SC+ F TT     A  +    +   AEQ ++    +   H    
Sbjct: 1149 RPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTK 1208

Query: 184  GLPSQAFEYILYNKGIMGEDTY 205
            G+  Q  E I+ +  +M ED +
Sbjct: 1209 GIVFQHPE-IVAHMDLMREDLH 1229


>gi|239756740 PREDICTED: similar to CMT1A duplicated region
           transcript 1 [Homo sapiens]
          Length = 433

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 26/113 (23%), Positives = 41/113 (36%), Gaps = 21/113 (18%)

Query: 18  PVCGAAELCVNSLEKFHFKSW----------------MSKHRKTYSTEEYHHRLQT---- 57
           P+C   E CV + + F  K W                + +    Y    + + LQT    
Sbjct: 26  PLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGILKQLNSLYLLHYFQNILQTTQGK 85

Query: 58  -FASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNY 109
            F  N  +IN         K +LNQ  D +  +   + L+    +   TK+NY
Sbjct: 86  DFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKEILYWFANSTQWTKANY 138


>gi|205360934 fibronectin type III domain containing 3B [Homo sapiens]
          Length = 1204

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 5/75 (6%)

Query: 38   WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKM-ALNQFSDMSF----AEIKH 92
            W   + KT++ E+  + LQ    N R I+ +   +HT+K+  L +F+  SF    A    
Sbjct: 978  WGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAG 1037

Query: 93   KYLWSEPQNCSATKS 107
            +  +SE    S TKS
Sbjct: 1038 EGPFSETYTFSTTKS 1052


>gi|205360932 fibronectin type III domain containing 3B [Homo sapiens]
          Length = 1204

 Score = 30.4 bits (67), Expect = 2.3
 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 5/75 (6%)

Query: 38   WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKM-ALNQFSDMSF----AEIKH 92
            W   + KT++ E+  + LQ    N R I+ +   +HT+K+  L +F+  SF    A    
Sbjct: 978  WGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAG 1037

Query: 93   KYLWSEPQNCSATKS 107
            +  +SE    S TKS
Sbjct: 1038 EGPFSETYTFSTTKS 1052


>gi|12746412 ankyrin repeat, family A (RFXANK-like), 2 [Homo
           sapiens]
          Length = 313

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 13/36 (36%), Positives = 20/36 (55%)

Query: 151 ESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLP 186
           ESA+++A  K  +   + L+DC  D N +   GG P
Sbjct: 216 ESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTP 251


>gi|124286830 zinc finger protein 618 [Homo sapiens]
          Length = 861

 Score = 28.5 bits (62), Expect = 8.8
 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 5/49 (10%)

Query: 13  WLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASN 61
           WLL VP  GA   CVN  E    ++ + K R+  S E+  ++L    SN
Sbjct: 816 WLLAVPAVGARSGCVNMCE----QALLIKRRRLLSPEDM-NKLMFLKSN 859


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,972,028
Number of Sequences: 37866
Number of extensions: 603527
Number of successful extensions: 1388
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1292
Number of HSP's gapped (non-prelim): 35
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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