BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] (335 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] 717 0.0 gi|23110957 cathepsin H isoform b precursor [Homo sapiens] 682 0.0 gi|22202619 cathepsin L1 preproprotein [Homo sapiens] 229 3e-60 gi|4503155 cathepsin L1 preproprotein [Homo sapiens] 229 3e-60 gi|23110960 cathepsin L2 preproprotein [Homo sapiens] 229 3e-60 gi|4503151 cathepsin K preproprotein [Homo sapiens] 227 1e-59 gi|23110962 cathepsin S preproprotein [Homo sapiens] 202 3e-52 gi|6042196 cathepsin F [Homo sapiens] 184 1e-46 gi|23110964 cathepsin W preproprotein [Homo sapiens] 153 2e-37 gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens] 148 8e-36 gi|4557501 cathepsin O preproprotein [Homo sapiens] 147 2e-35 gi|22538437 cathepsin B preproprotein [Homo sapiens] 112 6e-25 gi|22538435 cathepsin B preproprotein [Homo sapiens] 112 6e-25 gi|22538433 cathepsin B preproprotein [Homo sapiens] 112 6e-25 gi|22538431 cathepsin B preproprotein [Homo sapiens] 112 6e-25 gi|4503139 cathepsin B preproprotein [Homo sapiens] 112 6e-25 gi|22538442 cathepsin Z preproprotein [Homo sapiens] 93 3e-19 gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa... 89 7e-18 gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] 84 2e-16 gi|239744067 PREDICTED: similar to Putative cathepsin L-like pro... 45 7e-05 gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens] 32 1.0 gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 31 1.8 gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 31 1.8 gi|239756740 PREDICTED: similar to CMT1A duplicated region trans... 30 2.3 gi|205360934 fibronectin type III domain containing 3B [Homo sap... 30 2.3 gi|205360932 fibronectin type III domain containing 3B [Homo sap... 30 2.3 gi|12746412 ankyrin repeat, family A (RFXANK-like), 2 [Homo sapi... 29 6.8 gi|124286830 zinc finger protein 618 [Homo sapiens] 28 8.8 >gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] Length = 335 Score = 717 bits (1851), Expect = 0.0 Identities = 335/335 (100%), Positives = 335/335 (100%) Query: 1 MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS 60 MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS Sbjct: 1 MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS 60 Query: 61 NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV 120 NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV Sbjct: 61 NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV 120 Query: 121 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 180 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG Sbjct: 121 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 180 Query: 181 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 240 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV Sbjct: 181 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 240 Query: 241 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK 300 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK Sbjct: 241 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK 300 Query: 301 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV 335 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV Sbjct: 301 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV 335 >gi|23110957 cathepsin H isoform b precursor [Homo sapiens] Length = 323 Score = 682 bits (1759), Expect = 0.0 Identities = 323/335 (96%), Positives = 323/335 (96%), Gaps = 12/335 (3%) Query: 1 MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS 60 MWATLPLLCA AELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS Sbjct: 1 MWATLPLLCA------------AELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFAS 48 Query: 61 NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV 120 NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV Sbjct: 49 NWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSV 108 Query: 121 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 180 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG Sbjct: 109 DWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 168 Query: 181 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 240 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV Sbjct: 169 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 228 Query: 241 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK 300 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK Sbjct: 229 EAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK 288 Query: 301 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV 335 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV Sbjct: 289 NSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV 323 >gi|22202619 cathepsin L1 preproprotein [Homo sapiens] Length = 333 Score = 229 bits (583), Expect = 3e-60 Identities = 130/339 (38%), Positives = 188/339 (55%), Gaps = 23/339 (6%) Query: 6 PLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKI 65 P L A+ LG+ +A L + + + W + H + Y E R + N + I Sbjct: 3 PTLILAAFCLGI---ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMI 59 Query: 66 NAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPS 119 HN G H+F MA+N F DM+ E + + + QN K + Y P S Sbjct: 60 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLFYEAPRS 117 Query: 120 VDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNH 179 VDWR+KG +V+PVKNQG CGSCW FS TGALE + TG+++SL+EQ LVDC+ N Sbjct: 118 VDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE 176 Query: 180 GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI-YDEEA 238 GC GGL AF+Y+ N G+ E++YPY+ + CK+ P ++ D + I E+A Sbjct: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSV--ANDTGFVDIPKQEKA 234 Query: 239 MVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNG 293 +++AVA P+S A + + F+ Y+ GIY C + + ++H VL VGYG E + Sbjct: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDN 292 Query: 294 IPYWIVKNSWGPQWGMNGYFLIERG-KNMCGLAACASYP 331 YW+VKNSWG +WGM GY + + +N CG+A+ ASYP Sbjct: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331 >gi|4503155 cathepsin L1 preproprotein [Homo sapiens] Length = 333 Score = 229 bits (583), Expect = 3e-60 Identities = 130/339 (38%), Positives = 188/339 (55%), Gaps = 23/339 (6%) Query: 6 PLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKI 65 P L A+ LG+ +A L + + + W + H + Y E R + N + I Sbjct: 3 PTLILAAFCLGI---ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMI 59 Query: 66 NAHNN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPY--PPS 119 HN G H+F MA+N F DM+ E + + + QN K + Y P S Sbjct: 60 ELHNQEYREGKHSFTMAMNAFGDMTSEEFRQ--VMNGFQNRKPRKGKVFQEPLFYEAPRS 117 Query: 120 VDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNH 179 VDWR+KG +V+PVKNQG CGSCW FS TGALE + TG+++SL+EQ LVDC+ N Sbjct: 118 VDWREKG-YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNE 176 Query: 180 GCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI-YDEEA 238 GC GGL AF+Y+ N G+ E++YPY+ + CK+ P ++ D + I E+A Sbjct: 177 GCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSV--ANDTGFVDIPKQEKA 234 Query: 239 MVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYG----EKNG 293 +++AVA P+S A + + F+ Y+ GIY C + + ++H VL VGYG E + Sbjct: 235 LMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDC--SSEDMDHGVLVVGYGFESTESDN 292 Query: 294 IPYWIVKNSWGPQWGMNGYFLIERG-KNMCGLAACASYP 331 YW+VKNSWG +WGM GY + + +N CG+A+ ASYP Sbjct: 293 NKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYP 331 >gi|23110960 cathepsin L2 preproprotein [Homo sapiens] Length = 334 Score = 229 bits (583), Expect = 3e-60 Identities = 124/304 (40%), Positives = 166/304 (54%), Gaps = 13/304 (4%) Query: 38 WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSFAEIKHK 93 W + HR+ Y E R + N + I HN G H F MA+N F DM+ E + Sbjct: 32 WKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQM 91 Query: 94 YLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESA 153 Q K P SVDWRKKG +V+PVKNQ CGSCW FS TGALE Sbjct: 92 MGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKG-YVTPVKNQKQCGSCWAFSATGALEGQ 150 Query: 154 IAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGY 213 + TGK++SL+EQ LVDC++ N GC GG ++AF+Y+ N G+ E++YPY D Sbjct: 151 MFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI 210 Query: 214 CKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSC 272 CK++P ++ + E+A+++AVA P+S A + F Y++GIY C Sbjct: 211 CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDC 270 Query: 273 HKTPDKVNHAVLAVGYG----EKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAAC 327 + ++H VL VGYG N YW+VKNSWGP+WG NGY I + K N CG+A Sbjct: 271 --SSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATA 328 Query: 328 ASYP 331 ASYP Sbjct: 329 ASYP 332 >gi|4503151 cathepsin K preproprotein [Homo sapiens] Length = 329 Score = 227 bits (579), Expect = 1e-59 Identities = 128/309 (41%), Positives = 176/309 (56%), Gaps = 17/309 (5%) Query: 34 HFKSWMSKHRKTYST--EEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSF 87 H++ W HRK Y+ +E RL + N + I+ HN G HT+++A+N DM+ Sbjct: 25 HWELWKKTHRKQYNNKVDEISRRL-IWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTS 83 Query: 88 AEIKHKYLWSEPQNCSATKSNYL---RGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTF 144 E+ K + + ++ L G P SVD+RKKG +V+PVKNQG CGSCW F Sbjct: 84 EEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKG-YVTPVKNQGQCGSCWAF 142 Query: 145 STTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDT 204 S+ GALE + TGK+L+L+ Q LVDC + N GC GG + AF+Y+ N+GI ED Sbjct: 143 SSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDA 200 Query: 205 YPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVT-QDFMMYR 263 YPY G++ C + P + I +E+A+ AVA PVS A + + F Y Sbjct: 201 YPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYS 260 Query: 264 TGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMC 322 G+Y SC+ D +NHAVLAVGYG + G +WI+KNSWG WG GY L+ R K N C Sbjct: 261 KGVYYDESCNS--DNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNAC 318 Query: 323 GLAACASYP 331 G+A AS+P Sbjct: 319 GIANLASFP 327 >gi|23110962 cathepsin S preproprotein [Homo sapiens] Length = 331 Score = 202 bits (515), Expect = 3e-52 Identities = 119/310 (38%), Positives = 167/310 (53%), Gaps = 19/310 (6%) Query: 34 HFKSWMSKHRKTYS--TEEYHHRLQTFASNWRKINAHN----NGNHTFKMALNQFSDMSF 87 H+ W + K Y EE RL + N + + HN G H++ + +N DM+ Sbjct: 27 HWHLWKKTYGKQYKEKNEEAVRRL-IWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTS 85 Query: 88 AEIKHKYLWSEPQNCSATKSNYLRGTGP---YPPSVDWRKKGNFVSPVKNQGACGSCWTF 144 E+ L S + S + N + P P SVDWR+KG V+ VK QG+CG+CW F Sbjct: 86 EEVMS--LMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKG-CVTEVKYQGSCGACWAF 142 Query: 145 STTGALESAIAIATGKMLSLAEQQLVDCA-QDFNNHGCQGGLPSQAFEYILYNKGIMGED 203 S GALE+ + + TGK++SL+ Q LVDC+ + + N GC GG + AF+YI+ NKGI + Sbjct: 143 SAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDA 202 Query: 204 TYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQ-DFMMY 262 +YPY+ D C++ + E+ + EAVA PVS + F +Y Sbjct: 203 SYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLY 262 Query: 263 RTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NM 321 R+G+Y SC VNH VL VGYG+ NG YW+VKNSWG +G GY + R K N Sbjct: 263 RSGVYYEPSC---TQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNH 319 Query: 322 CGLAACASYP 331 CG+A+ SYP Sbjct: 320 CGIASFPSYP 329 >gi|6042196 cathepsin F [Homo sapiens] Length = 484 Score = 184 bits (467), Expect = 1e-46 Identities = 111/300 (37%), Positives = 159/300 (53%), Gaps = 12/300 (4%) Query: 35 FKSWMSKHRKTY-STEEYHHRLQTFASNW---RKINAHNNGNHTFKMALNQFSDMSFAEI 90 FK+++ + +TY S EE RL F +N +KI A + G T + + +FSD++ E Sbjct: 187 FKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRG--TAQYGVTKFSDLTEEEF 244 Query: 91 KHKYLWSEPQNCSATKSNYLRGTGPY-PPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGA 149 + YL + + K + G PP DWR KG V+ VK+QG CGSCW FS TG Sbjct: 245 RTIYLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGA-VTKVKDQGMCGSCWAFSVTGN 303 Query: 150 LESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQG 209 +E + G +LSL+EQ+L+DC D + C GGLPS A+ I G+ ED Y YQG Sbjct: 304 VEGQWFLNQGTLLSLSEQELLDC--DKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQG 361 Query: 210 KDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSS 269 C F KA ++ D ++ +E+ + +A P+S A YR GI Sbjct: 362 HMQSCNFSAEKAKVYINDSVELS-QNEQKLAAWLAKRGPISVAINAF-GMQFYRHGISRP 419 Query: 270 TSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACAS 329 +P ++HAVL VGYG ++ +P+W +KNSWG WG GY+ + RG CG+ AS Sbjct: 420 LRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMAS 479 >gi|23110964 cathepsin W preproprotein [Homo sapiens] Length = 376 Score = 153 bits (386), Expect = 2e-37 Identities = 97/319 (30%), Positives = 153/319 (47%), Gaps = 35/319 (10%) Query: 35 FKSWMSKHRKTY-STEEYHHRLQTFASNW---RKINAHNNGNHTFKMALNQFSDMSFAEI 90 FK + + ++Y S EE+ HRL FA N +++ + G T + + FSD++ E Sbjct: 42 FKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLG--TAEFGVTPFSDLTEEEF 99 Query: 91 KHKYLWSEPQNCSATKSNYLRGTGP---YPPSVDWRKKGNFVSPVKNQGACGSCWTFSTT 147 Y + + +R P P S DWRK +SP+K+Q C CW + Sbjct: 100 GQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAA 159 Query: 148 GALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPY 207 G +E+ I+ + ++ Q+L+DC + GC GG AF +L N G+ E YP+ Sbjct: 160 GNIETLWRISFWDFVDVSVQELLDCGRC--GDGCHGGFVWDAFITVLNNSGLASEKDYPF 217 Query: 208 QGKDGYCKFQPGK--AIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTG 265 QGK + P K + +++D + +E + + +A Y P++ + + +YR G Sbjct: 218 QGKVRAHRCHPKKYQKVAWIQDFIMLQ-NNEHRIAQYLATYGPITVTINM-KPLQLYRKG 275 Query: 266 IYSSTSCHKTPDKVNHAVLAVGYGE---KNGI-----------------PYWIVKNSWGP 305 + +T P V+H+VL VG+G + GI PYWI+KNSWG Sbjct: 276 VIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGA 335 Query: 306 QWGMNGYFLIERGKNMCGL 324 QWG GYF + RG N CG+ Sbjct: 336 QWGEKGYFRLHRGSNTCGI 354 >gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens] Length = 463 Score = 148 bits (373), Expect = 8e-36 Identities = 91/232 (39%), Positives = 126/232 (54%), Gaps = 17/232 (7%) Query: 117 PPSVDWRKKG--NFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLS--LAEQQLVDC 172 P S DWR NFVSPV+NQ +CGSC++F++ G LE+ I I T + L+ Q++V C Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291 Query: 173 AQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANIT 232 +Q GC+GG P + G++ E +PY G D CK + + + + Sbjct: 292 SQ--YAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVG 349 Query: 233 IY----DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHK--TP-DKVNHAVLA 285 + +E M + + P++ AFEV DF+ Y+ GIY T P + NHAVL Sbjct: 350 GFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLL 409 Query: 286 VGYG--EKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL--AACASYPIP 333 VGYG +G+ YWIVKNSWG WG NGYF I RG + C + A A+ PIP Sbjct: 410 VGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIP 461 >gi|4557501 cathepsin O preproprotein [Homo sapiens] Length = 321 Score = 147 bits (370), Expect = 2e-35 Identities = 90/267 (33%), Positives = 134/267 (50%), Gaps = 20/267 (7%) Query: 72 NHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTG--PYPPSVDWRKKGNFV 129 N T +NQFS + E K YL S+P + P DWR K V Sbjct: 62 NSTAFYGINQFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDK-QVV 120 Query: 130 SPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQA 189 + V+NQ CG CW FS GA+ESA AI + L+ QQ++DC+ +NN+GC GG A Sbjct: 121 TQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCS--YNNYGCNGGSTLNA 178 Query: 190 FEYILYNK---GIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYD----EEAMVEA 242 ++ NK ++ + YP++ ++G C + G GF + + YD E+ M +A Sbjct: 179 LNWL--NKMQVKLVKDSEYPFKAQNGLCHYFSGSHSGF--SIKGYSAYDFSDQEDEMAKA 234 Query: 243 VALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 302 + + P+ + + Y GI H + + NHAVL G+ + PYWIV+NS Sbjct: 235 LLTFGPLVVIVDAVS-WQDYLGGIIQH---HCSSGEANHAVLITGFDKTGSTPYWIVRNS 290 Query: 303 WGPQWGMNGYFLIERGKNMCGLAACAS 329 WG WG++GY ++ G N+CG+A S Sbjct: 291 WGSSWGVDGYAHVKMGSNVCGIADSVS 317 >gi|22538437 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 112 bits (279), Expect = 6e-25 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%) Query: 91 KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128 K W N +YL+ GT GP PP + D + +F Sbjct: 36 KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95 Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186 + +++QG+CGSCW F A+ I I T +S+ + + L+ C GC GG P Sbjct: 96 IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155 Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219 ++A+ + KG++ Y PY +G C +PG Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214 Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274 + + +D + ++ + E + A N PV AF V DF++Y++G+Y H Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270 Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333 T + + HA+ +G+G +NG PYW+V NSW WG NG+F I RG++ CG+ + IP Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 >gi|22538435 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 112 bits (279), Expect = 6e-25 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%) Query: 91 KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128 K W N +YL+ GT GP PP + D + +F Sbjct: 36 KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95 Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186 + +++QG+CGSCW F A+ I I T +S+ + + L+ C GC GG P Sbjct: 96 IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155 Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219 ++A+ + KG++ Y PY +G C +PG Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214 Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274 + + +D + ++ + E + A N PV AF V DF++Y++G+Y H Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270 Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333 T + + HA+ +G+G +NG PYW+V NSW WG NG+F I RG++ CG+ + IP Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 >gi|22538433 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 112 bits (279), Expect = 6e-25 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%) Query: 91 KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128 K W N +YL+ GT GP PP + D + +F Sbjct: 36 KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95 Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186 + +++QG+CGSCW F A+ I I T +S+ + + L+ C GC GG P Sbjct: 96 IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155 Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219 ++A+ + KG++ Y PY +G C +PG Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214 Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274 + + +D + ++ + E + A N PV AF V DF++Y++G+Y H Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270 Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333 T + + HA+ +G+G +NG PYW+V NSW WG NG+F I RG++ CG+ + IP Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 >gi|22538431 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 112 bits (279), Expect = 6e-25 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%) Query: 91 KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128 K W N +YL+ GT GP PP + D + +F Sbjct: 36 KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95 Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186 + +++QG+CGSCW F A+ I I T +S+ + + L+ C GC GG P Sbjct: 96 IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155 Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219 ++A+ + KG++ Y PY +G C +PG Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214 Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274 + + +D + ++ + E + A N PV AF V DF++Y++G+Y H Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270 Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333 T + + HA+ +G+G +NG PYW+V NSW WG NG+F I RG++ CG+ + IP Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 >gi|4503139 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 112 bits (279), Expect = 6e-25 Identities = 84/300 (28%), Positives = 133/300 (44%), Gaps = 62/300 (20%) Query: 91 KHKYLWSEPQNCSATKSNYLR---GT---GPYPP-----SVDWRKKGNF----------- 128 K W N +YL+ GT GP PP + D + +F Sbjct: 36 KRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPT 95 Query: 129 VSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSL--AEQQLVDCAQDFNNHGCQGGLP 186 + +++QG+CGSCW F A+ I I T +S+ + + L+ C GC GG P Sbjct: 96 IKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYP 155 Query: 187 SQAFEYILYNKGIMGEDTY-------PY------------------QGKDGYCK--FQPG 219 ++A+ + KG++ Y PY +G C +PG Sbjct: 156 AEAWNFWT-RKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPG 214 Query: 220 KAIGFVKD----VANITIYDEEAMVEAVALYN-PVSFAFEVTQDFMMYRTGIYSSTSCHK 274 + + +D + ++ + E + A N PV AF V DF++Y++G+Y H Sbjct: 215 YSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQ----HV 270 Query: 275 TPDKVN-HAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIP 333 T + + HA+ +G+G +NG PYW+V NSW WG NG+F I RG++ CG+ + IP Sbjct: 271 TGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIP 330 >gi|22538442 cathepsin Z preproprotein [Homo sapiens] Length = 303 Score = 93.2 bits (230), Expect = 3e-19 Identities = 67/220 (30%), Positives = 95/220 (43%), Gaps = 28/220 (12%) Query: 117 PPSVDWRKKG--NFVSPVKNQGA---CGSCWTFSTTGALESAIAI---ATGKMLSLAEQQ 168 P S DWR N+ S +NQ CGSCW ++T A+ I I L+ Q Sbjct: 63 PKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQN 122 Query: 169 LVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYC-KFQPGKAIGFVKD 227 ++DC N C+GG ++Y + GI E YQ KD C KF K+ Sbjct: 123 VIDCG---NAGSCEGGNDLSVWDYA-HQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKE 178 Query: 228 ---VANITIY---------DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKT 275 + N T++ E M+ + P+S T+ Y GIY+ ++ Sbjct: 179 CHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAE---YQD 235 Query: 276 PDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLI 315 +NH V G+G +G YWIV+NSWG WG G+ I Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275 >gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sapiens] Length = 467 Score = 88.6 bits (218), Expect = 7e-18 Identities = 67/237 (28%), Positives = 100/237 (42%), Gaps = 42/237 (17%) Query: 127 NFVSPVKNQGACGSCWTFSTTGALESAIAI-ATGKMLS-LAEQQLVDCAQDFNNHGCQGG 184 N + +QG C W FST ++I + G M L+ Q L+ C GC+GG Sbjct: 215 NLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSC-DTHQQQGCRGG 273 Query: 185 LPSQAFEYILYNKGIMGEDTYPYQGKD-------------------------GYC--KFQ 217 A+ + L +G++ + YP+ G++ +C + Sbjct: 274 RLDGAW-WFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYV 332 Query: 218 PGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHK-TP 276 I V V + D+E M E + PV EV +DF +Y+ GIYS T P Sbjct: 333 NNNDIYQVTPVYRLGSNDKEIMKELME-NGPVQALMEVHEDFFLYKGGIYSHTPVSLGRP 391 Query: 277 DKVN----HAVLAVGYGEKN-----GIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 324 ++ H+V G+GE+ + YW NSWGP WG G+F I RG N C + Sbjct: 392 ERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDI 448 >gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] Length = 476 Score = 83.6 bits (205), Expect = 2e-16 Identities = 69/223 (30%), Positives = 95/223 (42%), Gaps = 39/223 (17%) Query: 134 NQGACGSCWTFSTTGALESAIAIAT-GKMLS-LAEQQLVDCAQDFNNHGCQGGLPSQAFE 191 +Q C + W FST IAI + G+ + L+ Q L+ C N HGC G +A+ Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAK-NRHGCNSGSIDRAWW 294 Query: 192 YILYNKGIMGEDTYPY--------------QGKDGYCKFQPGKAIGFVKDVANITIY--- 234 Y L +G++ YP DG K K + +N IY Sbjct: 295 Y-LRKRGLVSHACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSN-RIYQCS 352 Query: 235 -------DEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSS-TSCHKTPDKVN----HA 282 +E +++ + PV +V +DF Y+TGIY TS +K +K HA Sbjct: 353 PPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHA 412 Query: 283 VLAVGYGEKNGIP-----YWIVKNSWGPQWGMNGYFLIERGKN 320 V G+G G +WI NSWG WG NGYF I RG N Sbjct: 413 VKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455 >gi|239744067 PREDICTED: similar to Putative cathepsin L-like protein 6 [Homo sapiens] Length = 81 Score = 45.4 bits (106), Expect = 7e-05 Identities = 25/71 (35%), Positives = 42/71 (59%), Gaps = 7/71 (9%) Query: 68 HNNGNHTFKMALNQFSDMS---FAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRK 124 ++ G H+F MA+N F DM+ F ++ + + + + +N + L P SVDWR+ Sbjct: 11 YSQGKHSFTMAMNTFGDMTTEEFRQVMNGFQYQKHRNGKQFQERLLL---EIPTSVDWRE 67 Query: 125 KGNFVSPVKNQ 135 KG +V+PVK+Q Sbjct: 68 KG-YVTPVKDQ 77 >gi|110815834 F-box and WD-40 domain protein 10 [Homo sapiens] Length = 1051 Score = 31.6 bits (70), Expect = 1.0 Identities = 26/114 (22%), Positives = 42/114 (36%), Gaps = 21/114 (18%) Query: 17 VPVCGAAELCVNSLEKFHFKSW----------------MSKHRKTYSTEEYHHRLQT--- 57 +P+C E CV + + F K W + + Y + + LQT Sbjct: 23 IPLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGILKQLNSLYLLHYFQNILQTTQG 82 Query: 58 --FASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNY 109 F N +IN K +LNQ D + + + L+ + TK+NY Sbjct: 83 KDFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKEILYWFANSTQWTKANY 136 >gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo sapiens] Length = 3118 Score = 30.8 bits (68), Expect = 1.8 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 1/82 (1%) Query: 124 KKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQG 183 + G F KN C SC+ F TT A + + AEQ ++ + H Sbjct: 1149 RPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTK 1208 Query: 184 GLPSQAFEYILYNKGIMGEDTY 205 G+ Q E I+ + +M ED + Sbjct: 1209 GIVFQHPE-IVAHMDLMREDLH 1229 >gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sapiens] Length = 3122 Score = 30.8 bits (68), Expect = 1.8 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 1/82 (1%) Query: 124 KKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQG 183 + G F KN C SC+ F TT A + + AEQ ++ + H Sbjct: 1149 RPGKFGLDAKNPLGCSSCYCFGTTTQCSEAKGLIRTWVTLKAEQTILPLVDEALQHTTTK 1208 Query: 184 GLPSQAFEYILYNKGIMGEDTY 205 G+ Q E I+ + +M ED + Sbjct: 1209 GIVFQHPE-IVAHMDLMREDLH 1229 >gi|239756740 PREDICTED: similar to CMT1A duplicated region transcript 1 [Homo sapiens] Length = 433 Score = 30.4 bits (67), Expect = 2.3 Identities = 26/113 (23%), Positives = 41/113 (36%), Gaps = 21/113 (18%) Query: 18 PVCGAAELCVNSLEKFHFKSW----------------MSKHRKTYSTEEYHHRLQT---- 57 P+C E CV + + F K W + + Y + + LQT Sbjct: 26 PLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGILKQLNSLYLLHYFQNILQTTQGK 85 Query: 58 -FASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNY 109 F N +IN K +LNQ D + + + L+ + TK+NY Sbjct: 86 DFIYNRSRINLSKKEGKVVKSSLNQMLDKTVEQKMKEILYWFANSTQWTKANY 138 >gi|205360934 fibronectin type III domain containing 3B [Homo sapiens] Length = 1204 Score = 30.4 bits (67), Expect = 2.3 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 5/75 (6%) Query: 38 WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKM-ALNQFSDMSF----AEIKH 92 W + KT++ E+ + LQ N R I+ + +HT+K+ L +F+ SF A Sbjct: 978 WGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAG 1037 Query: 93 KYLWSEPQNCSATKS 107 + +SE S TKS Sbjct: 1038 EGPFSETYTFSTTKS 1052 >gi|205360932 fibronectin type III domain containing 3B [Homo sapiens] Length = 1204 Score = 30.4 bits (67), Expect = 2.3 Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 5/75 (6%) Query: 38 WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKM-ALNQFSDMSF----AEIKH 92 W + KT++ E+ + LQ N R I+ + +HT+K+ L +F+ SF A Sbjct: 978 WGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAG 1037 Query: 93 KYLWSEPQNCSATKS 107 + +SE S TKS Sbjct: 1038 EGPFSETYTFSTTKS 1052 >gi|12746412 ankyrin repeat, family A (RFXANK-like), 2 [Homo sapiens] Length = 313 Score = 28.9 bits (63), Expect = 6.8 Identities = 13/36 (36%), Positives = 20/36 (55%) Query: 151 ESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLP 186 ESA+++A K + + L+DC D N + GG P Sbjct: 216 ESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTP 251 >gi|124286830 zinc finger protein 618 [Homo sapiens] Length = 861 Score = 28.5 bits (62), Expect = 8.8 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 5/49 (10%) Query: 13 WLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASN 61 WLL VP GA CVN E ++ + K R+ S E+ ++L SN Sbjct: 816 WLLAVPAVGARSGCVNMCE----QALLIKRRRLLSPEDM-NKLMFLKSN 859 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.134 0.440 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,972,028 Number of Sequences: 37866 Number of extensions: 603527 Number of successful extensions: 1388 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 6 Number of HSP's that attempted gapping in prelim test: 1292 Number of HSP's gapped (non-prelim): 35 length of query: 335 length of database: 18,247,518 effective HSP length: 103 effective length of query: 232 effective length of database: 14,347,320 effective search space: 3328578240 effective search space used: 3328578240 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.