Guide to the Human Genome
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Search of human proteins with 229577273

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|229577273 BUD13 homolog isoform 2 [Homo sapiens]
         (485 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|229577273 BUD13 homolog isoform 2 [Homo sapiens]                  1001   0.0  
gi|14249338 BUD13 homolog isoform 1 [Homo sapiens]                    904   0.0  
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         75   1e-13
gi|217330641 IWS1 homolog [Homo sapiens]                               74   2e-13
gi|47578107 delangin isoform B [Homo sapiens]                          62   2e-09
gi|47578105 delangin isoform A [Homo sapiens]                          62   2e-09
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             60   4e-09
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              59   1e-08
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    57   5e-08
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           56   6e-08
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          56   8e-08
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        55   1e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                54   3e-07
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    54   4e-07
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    54   4e-07
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         52   9e-07
gi|4504487 histidine rich calcium binding protein precursor [Hom...    52   2e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     51   2e-06
gi|148746195 trichohyalin [Homo sapiens]                               50   6e-06
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    50   6e-06
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    50   6e-06
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    49   8e-06
gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens]    49   1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   1e-05
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     48   2e-05
gi|50083281 KIAA1853 protein [Homo sapiens]                            47   3e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    47   5e-05
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot...    46   7e-05
gi|169166499 PREDICTED: similar to ribonucleic acid binding prot...    46   7e-05
gi|113415498 PREDICTED: similar to ribonucleic acid binding prot...    46   7e-05

>gi|229577273 BUD13 homolog isoform 2 [Homo sapiens]
          Length = 485

 Score = 1001 bits (2587), Expect = 0.0
 Identities = 485/485 (100%), Positives = 485/485 (100%)

Query: 1   MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60
           MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA
Sbjct: 1   MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60

Query: 61  ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
           ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR
Sbjct: 61  ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120

Query: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180
           HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI
Sbjct: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180

Query: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDL 240
           RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDL
Sbjct: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDL 240

Query: 241 SPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTD 300
           SPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTD
Sbjct: 241 SPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTD 300

Query: 301 IQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELY 360
           IQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELY
Sbjct: 301 IQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELY 360

Query: 361 AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKA 420
           AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKA
Sbjct: 361 AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKA 420

Query: 421 KENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKAVEELAYKW 480
           KENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKAVEELAYKW
Sbjct: 421 KENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKAVEELAYKW 480

Query: 481 SVEDM 485
           SVEDM
Sbjct: 481 SVEDM 485


>gi|14249338 BUD13 homolog isoform 1 [Homo sapiens]
          Length = 619

 Score =  904 bits (2337), Expect = 0.0
 Identities = 474/619 (76%), Positives = 476/619 (76%), Gaps = 134/619 (21%)

Query: 1   MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60
           MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA
Sbjct: 1   MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60

Query: 61  ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
           ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR
Sbjct: 61  ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120

Query: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDS-------- 172
           HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDS        
Sbjct: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180

Query: 173 -------------------------------------------DTSPPRRIRHDSSDTSP 189
                                                      D SPPRR RH SSD S 
Sbjct: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISS 240

Query: 190 PR-----------------------RARHDSPDP-------------------------- 200
           PR                       RARHDSPD                           
Sbjct: 241 PRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSP 300

Query: 201 ------------------------SPPRRPQH----------NSSGDCQKATDSDLSSPR 226
                                   SPPR+ Q           +S GDCQKATDSDLSSPR
Sbjct: 301 HWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPR 360

Query: 227 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 286
           HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA
Sbjct: 361 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 420

Query: 287 HMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ 346
           HMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ
Sbjct: 421 HMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ 480

Query: 347 RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER 406
           RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER
Sbjct: 481 RRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQER 540

Query: 407 EGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFAR 466
           EGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFAR
Sbjct: 541 EGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFAR 600

Query: 467 LASKKAVEELAYKWSVEDM 485
           LASKKAVEELAYKWSVEDM
Sbjct: 601 LASKKAVEELAYKWSVEDM 619


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 78/279 (27%), Positives = 113/279 (40%), Gaps = 39/279 (13%)

Query: 29  ESGRKRRKK-RPKPGGAGGKGMRIVDDDVSWTAISTTKLEK----EEEEDDGDLPVVAEF 83
           +S R R+ +    PG   GK  +    +   +     K  K    E EED G     A+ 
Sbjct: 419 QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADS 478

Query: 84  VDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKD 143
           V +R +  +Q +  +SS+         ++ P   H ++       R     +  PSPRK 
Sbjct: 479 VQQRRQYRRQNQ--QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKR 536

Query: 144 RHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRR------ARHDS 197
           + +T   SPR  R  +P P P R  R  S   PPRR R   + T PPRR       R  S
Sbjct: 537 QKET---SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRR---TPTPPPRRRTPSPPPRRRS 590

Query: 198 PDP---SPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDS 254
           P P   SPP + +++ S   ++ T S    P+ + SP          PP+ R  H     
Sbjct: 591 PSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPS--------PPPKRRVSHSPPPK 642

Query: 255 DLSPPRRRQRTKSSDS----DLSPPR-----RSQPPGKK 284
             S P  ++R+ S  S      SP R     RS  P K+
Sbjct: 643 QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKR 681



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 73/239 (30%), Positives = 94/239 (39%), Gaps = 37/239 (15%)

Query: 68  KEEEEDDGDLPVVAEFVDERPEE--VKQMEAFRS-------SAKWKLLGGHNEDLPSNRH 118
           ++ ++   D    +   DERP+   VK  E  R        SA         E  P  R 
Sbjct: 487 RQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRR 546

Query: 119 FRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPR 178
            R  +P  + RR R  +P P PR+ R  TP P PRR    TP P P R +      SPP 
Sbjct: 547 RRSPSPPPTRRR-RSPSPAPPPRRRR--TPTPPPRRR---TPSPPPRRRSPSPRRYSPPI 600

Query: 179 RIRHDSSD-------TSPPRRARHDSPDPSPPRRPQHN-----SSGDCQKATDSDLSSPR 226
           + R+  S        + PP   R  SP P P RR  H+      S    K     LSS  
Sbjct: 601 QRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660

Query: 227 HKQSPGHQDSDSDLSPPRNR-----PRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQP 280
            K S   + +    SP  N+     PR R+  +  SPP  R+   S     SP RR  P
Sbjct: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS-----SPQRRQSP 714



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 59/223 (26%), Positives = 96/223 (43%), Gaps = 26/223 (11%)

Query: 79  VVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDS--------SPRR 130
           + + F++ + EE+KQ    R   + KL     +D   ++  + +   S        SPRR
Sbjct: 119 IPSAFLELKKEEIKQ----RQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRR 174

Query: 131 VRHGTPDP----SP-RKDRHDTPDPSPR-RARHDTPDPSPLRGARHDSDTSPPRRIRHDS 184
            +  +P P    SP R++R  +   SPR R +  +P P+P +  +      P  +++  S
Sbjct: 175 RKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPS 234

Query: 185 SD--TSPPRRARHDSPDPSP-PRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLS 241
               TS     +   P+P P P+ P    +   +K  + + + PR +     +      S
Sbjct: 235 VQEATSTSDILKVPKPEPIPEPKEPSPEKNS--KKEKEKEKTRPRSRSRSKSRSRTRSRS 292

Query: 242 PPRNRPR--HRSSDSDLSPPRR-RQRTKSSDSDLSPPRRSQPP 281
           P   RPR  HRS     SP RR   R + S    +PPRR  PP
Sbjct: 293 PSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPP 335



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 82/337 (24%), Positives = 118/337 (35%), Gaps = 57/337 (16%)

Query: 137 DPSPRKDRHDTPDPSPRRARHDTPDPSPLR-GARHDSDTSPPRRIRHDSSDTSPPRR--- 192
           +PSP K+     +    R R  +   S  R  +R  S T P RR R  S   SP RR   
Sbjct: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP 317

Query: 193 ARHDSPD--------PSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPR 244
            R  SP         P PPR  +  S    ++ + + LS      S     S    SPP+
Sbjct: 318 RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSG-----SSSSSSSSRSRSPPK 372

Query: 245 NRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQRE 304
             P+  S     SPPR+ +R   S    SPPRR   P   A                +  
Sbjct: 373 KPPKRTS-----SPPRKTRRLSPS---ASPPRRRHRPSPPAT------------PPPKTR 412

Query: 305 QQELKEQDQETMAFEAEFQYAET---VFRDKSGRKRNLKLERLEQRRKAEKDSERDELYA 361
                +Q   T           T   V + K   KR       + R+    +SE D+   
Sbjct: 413 HSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472

Query: 362 QWGKGLAQSRQQ-----QQNVED----AMKEMQKPLARYIDDEDLDRMLREQ-EREGDPM 411
                  Q R+Q     QQ+  D    +  E ++P   ++ + ++ R  R    R   P 
Sbjct: 473 MAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS 532

Query: 412 ANFIKKNKAKENKNKKV-------RPRYSGPAPPPNR 441
               +K  +   + ++        R R   PAPPP R
Sbjct: 533 PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRR 569



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 63/258 (24%), Positives = 97/258 (37%), Gaps = 57/258 (22%)

Query: 85  DERPEEVKQMEAFRSSAKWKLLGGHNEDLPSN----RHFRHDTPDSSPRRVRHGTPDPSP 140
           + + E+ K+    RS ++ K         PS+    R  R  +   SPRR       PSP
Sbjct: 264 NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSP 323

Query: 141 RK---DRHDTPDPSPRRARHDTPDPSPLRGARHDS------------------------- 172
           R+    R   P P  RR+R      SP+R  R  S                         
Sbjct: 324 RRRTPPRRMPPPPRHRRSR------SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR 377

Query: 173 DTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPG 232
            +SPPR+ R  S   SPPRR    SP  +PP + +H+ +      T     S    ++ G
Sbjct: 378 TSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG 437

Query: 233 ----HQDSDSDLSP-PRNRPRH--------------RSSDSDLSPPRRRQRTKSSDSDLS 273
               H+ ++   SP P  +PR                ++DS     + R++ + S SD  
Sbjct: 438 KVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSG 497

Query: 274 PPRRSQPPGKKAAHMYSG 291
               S+    K +H+ +G
Sbjct: 498 SSSSSEDERPKRSHVKNG 515



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 38/154 (24%), Positives = 57/154 (37%), Gaps = 38/154 (24%)

Query: 114 PSNRHFRHDTP-----DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGA 168
           P+ RH     P      SSP  VR G    SP++ +  +P   P R    TP+P  ++ A
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASS-SPQRRQSPSPSTRPIRRVSRTPEPKKIKKA 736

Query: 169 RHDSDTS-----------------------PPRRIRHDSSDTS-----PPRRARHDSPDP 200
              S  S                       PP  ++  S  T+     P ++A+  +P P
Sbjct: 737 ASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSP 796

Query: 201 SPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQ 234
           SPPR       G  +K         +HK+   H+
Sbjct: 797 SPPRNSDQEGGGKKKKKK----KDKKHKKDKKHK 826


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 81/349 (23%), Positives = 135/349 (38%), Gaps = 21/349 (6%)

Query: 85  DERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDR 144
           D   EE +++    S  + +LL GH  D  +    +H   DS    ++      SP  D 
Sbjct: 119 DSESEETRKLPGSDSENE-ELLNGHASDSENEDVGKHPASDSEIEELQK-----SPASDS 172

Query: 145 HDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPR 204
                  P+ +  ++ +P P   A    +  PP+    DS     P+    DS    PPR
Sbjct: 173 ETEDALKPQISDSESEEP-PRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPR 231

Query: 205 RPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR 264
               +S  +  +     +S    +  P HQ SDS+       P+ R SDS+   P R Q 
Sbjct: 232 HQASDSENE--ELPKPRISDSESEDPPRHQASDSE---NEELPKPRISDSESEDPPRNQA 286

Query: 265 TKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK---EQDQETMAFEAE 321
           + S + +L  PR S     ++     G  +     D  R +Q+ +   + D+E    + E
Sbjct: 287 SDSENEELPKPRVSD---SESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTE 343

Query: 322 FQYAETVFRDKSGRKRNLKLERLEQRRKAEK-DSERDELYAQWGKGLAQSRQQQQNVEDA 380
            Q           RK+    +  E+  K +K DS+ DE   +  K   +      + ED 
Sbjct: 344 MQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDE 403

Query: 381 MKEMQKP--LARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 427
            K   K   +    DD D D +  +  +    +A+  ++   KE  +KK
Sbjct: 404 EKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKK 452



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 76/372 (20%), Positives = 144/372 (38%), Gaps = 24/372 (6%)

Query: 27  GSESGRKRRKKRPKPGGAG-----GKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVA 81
           GS+S  +  +K P           G      ++DV     S +++E+ ++    D    +
Sbjct: 117 GSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASD----S 172

Query: 82  EFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPR 141
           E  D    ++   E+     + +     NE+ P  R    ++ +    +V     +  PR
Sbjct: 173 ETEDALKPQISDSES-EEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPR 231

Query: 142 KDRHDTPD---PSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSP 198
               D+ +   P PR +  ++ DP   + +  +++  P  RI  DS    PPR    DS 
Sbjct: 232 HQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRI-SDSESEDPPRNQASDSE 290

Query: 199 DPSPPR-RPQHNSSGDCQKATDSDL---SSPRHKQSP-GHQDSDSDLSPPRNRPRHRSSD 253
           +   P+ R   + S   QK   SD     + RHKQ P    DSD +        ++ S  
Sbjct: 291 NEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFH 350

Query: 254 SDLSPPRRRQRTKSSDSDLSPPRR--SQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQ 311
           SD    R++  +  S+ +    ++  S    K+        +   VL+D   E +E    
Sbjct: 351 SDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSD--SEDEEKASA 408

Query: 312 DQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSR 371
            +  +  +A+   ++ V  DKSG++        E+    E   +++E    +G       
Sbjct: 409 KKSRVVSDADDSDSDAV-SDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGN 467

Query: 372 QQQQNVEDAMKE 383
           +++  + D   E
Sbjct: 468 EEENLIADIFGE 479



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 72/340 (21%), Positives = 126/340 (37%), Gaps = 61/340 (17%)

Query: 107 GGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKD-----RH--DTPDPSPRRARHDT 159
           G   ED  + +H   DT        RH   + S R+D      H  D+ +  P       
Sbjct: 26  GSDGEDDVNEQHSGSDTGSVE----RHSENETSDREDGLPKGHHVTDSENDEPLNLNASD 81

Query: 160 PDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATD 219
            +   L   + DSD+    R    +SD+      +H S   S   R    S  + ++  +
Sbjct: 82  SESEELHRQK-DSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLN 140

Query: 220 SDLSSPRHKQSPGHQDSDSDL-----------------------SPPRNRPRHRSSDSDL 256
              S   ++    H  SDS++                       S     PRH++SDS+ 
Sbjct: 141 GHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSEN 200

Query: 257 SPPRRRQRTKSSDSDLSPPRRS-----QPPGKKAAHMYSGAKTGLVLTDIQRE----QQE 307
             P + + + S   +L  P+ S     +PP  +A+   +       ++D + E     Q 
Sbjct: 201 EEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQA 260

Query: 308 LKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGL 367
              +++E          +E   R+++    N   E L + R ++ +SE  +      KG 
Sbjct: 261 SDSENEELPKPRISDSESEDPPRNQASDSEN---EELPKPRVSDSESEGPQ------KGP 311

Query: 368 AQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE 407
           A   +     EDA +  QKP +    D+D DR  + ++ E
Sbjct: 312 ASDSE----TEDASRHKQKPES----DDDSDRENKGEDTE 343


>gi|47578107 delangin isoform B [Homo sapiens]
          Length = 2697

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 80/391 (20%), Positives = 151/391 (38%), Gaps = 35/391 (8%)

Query: 51   IVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHN 110
            IV+   +   +S TK   + ++++G     +E    RPE  KQ    R     +   GH 
Sbjct: 668  IVEPKQNENRLSDTK-PNDNKQNNGR----SETTKSRPETPKQKGESRPETPKQKSDGHP 722

Query: 111  EDLPSNRHFRHDTPDS-------SPRRVRHGTPD-PSPRKD-RHDTPDPS----PRRARH 157
            E        R +TP         +P++   G P+ P  R D R D+  PS    P  ++H
Sbjct: 723  ETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKH 782

Query: 158  --DTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQ 215
              DT   SP    R  S+ +   + R D    S   R  HD+   S  R       GD  
Sbjct: 783  KQDTKSDSP----RLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQS 838

Query: 216  KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPP 275
            +    +      +   G +   S       + RH S DS   P    Q+++        P
Sbjct: 839  RVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDS-----P 893

Query: 276  RRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGR 335
            R  Q    K+     G K+     D +R +    + D      + + ++   +   +SG 
Sbjct: 894  RVKQGDSNKSRSDKLGFKSP-TSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGA 952

Query: 336  KRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLA--RYID 393
             +N  + ++++ +      E  ++     KG  + + ++  + + + +  KP+   + + 
Sbjct: 953  LKNFVIPKIKRDKDGNVTQETKKMEM---KGEPKDKVEKIGLVEDLNKGAKPVVVLQKLS 1009

Query: 394  DEDLDRMLREQEREGDPMANFIKKNKAKENK 424
             +D+ ++++++E +       IK   +K NK
Sbjct: 1010 LDDVQKLIKDREDKSRSSLKPIKNKPSKSNK 1040


>gi|47578105 delangin isoform A [Homo sapiens]
          Length = 2804

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 80/391 (20%), Positives = 151/391 (38%), Gaps = 35/391 (8%)

Query: 51   IVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHN 110
            IV+   +   +S TK   + ++++G     +E    RPE  KQ    R     +   GH 
Sbjct: 668  IVEPKQNENRLSDTK-PNDNKQNNGR----SETTKSRPETPKQKGESRPETPKQKSDGHP 722

Query: 111  EDLPSNRHFRHDTPDS-------SPRRVRHGTPD-PSPRKD-RHDTPDPS----PRRARH 157
            E        R +TP         +P++   G P+ P  R D R D+  PS    P  ++H
Sbjct: 723  ETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKH 782

Query: 158  --DTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQ 215
              DT   SP    R  S+ +   + R D    S   R  HD+   S  R       GD  
Sbjct: 783  KQDTKSDSP----RLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQS 838

Query: 216  KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPP 275
            +    +      +   G +   S       + RH S DS   P    Q+++        P
Sbjct: 839  RVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDS-----P 893

Query: 276  RRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGR 335
            R  Q    K+     G K+     D +R +    + D      + + ++   +   +SG 
Sbjct: 894  RVKQGDSNKSRSDKLGFKSP-TSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGA 952

Query: 336  KRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLA--RYID 393
             +N  + ++++ +      E  ++     KG  + + ++  + + + +  KP+   + + 
Sbjct: 953  LKNFVIPKIKRDKDGNVTQETKKMEM---KGEPKDKVEKIGLVEDLNKGAKPVVVLQKLS 1009

Query: 394  DEDLDRMLREQEREGDPMANFIKKNKAKENK 424
             +D+ ++++++E +       IK   +K NK
Sbjct: 1010 LDDVQKLIKDREDKSRSSLKPIKNKPSKSNK 1040


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 72/270 (26%), Positives = 97/270 (35%), Gaps = 36/270 (13%)

Query: 4   APPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPG---GAGGKGMRIVDDDVSWTA 60
           APP   +  L R  S +D+G  RG+          P+PG   G GG G R  +       
Sbjct: 414 APPRGSSRSLSRARSSSDSGSGRGAPG------PGPEPGSERGHGGHGKRAKERPPRARP 467

Query: 61  ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
            ST+          G            PE        +SS++    G H     S+R   
Sbjct: 468 ASTSPSPGAHGRRGG------------PEG-------KSSSRSP--GPHPRSWSSSRSPS 506

Query: 121 HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180
                S+ +R    +  PSP+K      D    RARH   + +  R  R     SP R+ 
Sbjct: 507 KSRSRSAEKRPHSPSRSPSPKKPLSRDKD-GEGRARHSEAEAT--RARRRSRSYSPIRKR 563

Query: 181 RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDL 240
           R DS     PRR       P P  RP  +SS  C     SD S+  H +SP    S    
Sbjct: 564 RRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSC---LSSDYSTRSHSRSPSPGHSHGSY 620

Query: 241 SPPRNRPRHRSSDSDLSPPRRRQRTKSSDS 270
           S   +  R R+     +P        SS+S
Sbjct: 621 SSRSHGTRSRTRSPSRTPSPSYHSRSSSES 650



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/175 (28%), Positives = 59/175 (33%), Gaps = 14/175 (8%)

Query: 114 PSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSD 173
           P + H   D P S   RVR      +P         PSPR A           G      
Sbjct: 328 PGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRR 387

Query: 174 TSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGH 233
               RR R  SS ++P RR R   P P+PPR    + S   +  + SD  S R    PG 
Sbjct: 388 RRRRRRRRSRSSASAPRRRGRR-RPRPAPPRGSSRSLS---RARSSSDSGSGRGAPGPGP 443

Query: 234 QDSD----------SDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRS 278
           +             +   PPR RP   S        R     KSS     P  RS
Sbjct: 444 EPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRS 498



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 59/239 (24%), Positives = 92/239 (38%), Gaps = 27/239 (11%)

Query: 58  WTAISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNR 117
           W++ S +   K++++  G           R  + +++E+  S      L    + +  +R
Sbjct: 159 WSSSSASPPPKKKKKKKGG--------HRRSRKKRRLESECSCGSSSPLRKKKKSVKKHR 210

Query: 118 HFRHDTPDSSPRRVRHGTP-----DPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDS 172
             R D+     RR R  +      + +  K R  T  P  R  RH +        + H S
Sbjct: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYS 270

Query: 173 DTSPPRRI----RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHK 228
           D+  P R+    R +   T   R +   SP PS       +  G  Q+   S   S  H 
Sbjct: 271 DSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPS-----GGSGWGSPQRNGGSGQRSGAHG 325

Query: 229 QSPGHQDSDSDL-SPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 286
             PG   S  D  S P  R R +++ +  +PP    R K S S  S P  SQ  G +AA
Sbjct: 326 GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPP---ARGKESPSPRSAP-SSQGRGGRAA 380



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 50/190 (26%), Positives = 70/190 (36%), Gaps = 24/190 (12%)

Query: 109 HNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPS-------PRRARHDTPD 161
           H+  L S+          SP+    G    S R     +P PS       P+R    +  
Sbjct: 261 HSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQR-NGGSGQ 319

Query: 162 PSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRR------PQHNSSGDCQ 215
            S   G R  S  SPP +     S  SP  R +  +  P+PP R      P+   S   +
Sbjct: 320 RSGAHGGRPGSAHSPPDK----PSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGR 375

Query: 216 KATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKS---SDSDL 272
               +  +  R ++    + S S  S PR R R R      +PPR   R+ S   S SD 
Sbjct: 376 GGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRP---APPRGSSRSLSRARSSSDS 432

Query: 273 SPPRRSQPPG 282
              R +  PG
Sbjct: 433 GSGRGAPGPG 442



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 4/110 (3%)

Query: 179 RIRH-DSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSD 237
           R +H  SS  SPP + +          R +     +C   + S L   + K    H+   
Sbjct: 155 RTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRK-KKKSVKKHRRDR 213

Query: 238 SDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAH 287
           SD S  R + RHRS  S      + +  K   ++ SP RRS      ++H
Sbjct: 214 SD-SGSRRKRRHRSRSSKCKRKEKNKEKKRPHTE-SPGRRSHRHSSGSSH 261


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 56/195 (28%), Positives = 73/195 (37%), Gaps = 30/195 (15%)

Query: 119  FRHDTPDSSPRRVRHGTP-----DPSPRKDR------HDTPDP----SPRRARHDTPDPS 163
            +R  TP     R RH         PS R  R      H +P      SP R  H +P   
Sbjct: 1545 YRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSER 1604

Query: 164  PLRGARHDSDTSPPRRIRHDSSDT---SP-------PRRARHDSPDPSPPRRPQHNSSGD 213
              R     +  SPP R  H  S+    SP       P + RH SP     R P   S   
Sbjct: 1605 SWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSH-- 1662

Query: 214  CQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 273
             + +++    SP  +   G  +  S  SP   R R  S  S   P  RR  + S  S  S
Sbjct: 1663 -RSSSERRHRSPSQRSHRGPSER-SHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRS 1720

Query: 274  PPRRS-QPPGKKAAH 287
            P RRS + P +++ H
Sbjct: 1721 PARRSHRSPSERSHH 1735



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 59/202 (29%), Positives = 77/202 (38%), Gaps = 24/202 (11%)

Query: 114  PSNRHFRHDTPDS--SPRRVRHGTPDP----SPRKDRHDTPDP----SPRRARHDTPDPS 163
            PS R  R  +  S  SP   RH +P       P + RH +P      SP R  H +P   
Sbjct: 1673 PSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSER 1732

Query: 164  PLRGARHDSDTSPPRRIRHDSSDTS--PPRRARHDSPDPSPPRRP---QHNSSGDCQKAT 218
                    S  SP  R  H  S+ S   P    H SP     R P   +H+S  +    +
Sbjct: 1733 SHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHS 1792

Query: 219  DSDLS----SPRHKQSPGHQDSDSDLS----PPRNRPRHRSSDSDLSPPRRRQRTKSSDS 270
             S+ S    S R + SP  +   S L      P  R  HRS +        R  + S  S
Sbjct: 1793 PSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKS 1852

Query: 271  DLSPPRRSQ-PPGKKAAHMYSG 291
             LSP  RS+  P ++  H  SG
Sbjct: 1853 HLSPLERSRCSPSERRGHSSSG 1874



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 48/185 (25%), Positives = 68/185 (36%), Gaps = 13/185 (7%)

Query: 114  PSNRHFRHDTPDS--SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRG---A 168
            PS R  R  +  S  S    RH +P     +   +    SP   RH +P     RG    
Sbjct: 1649 PSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSER 1708

Query: 169  RHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPS--PPRRPQHNSSGDCQKATDSDLS--- 223
            RH S +    R     S  SP  R+ H   + S   P   +H+S  +    + S+ S   
Sbjct: 1709 RHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCS 1768

Query: 224  -SPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPG 282
             S R  +SP  +   S      + P  RS  S     R     +S  S L    RS  P 
Sbjct: 1769 PSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRS--PS 1826

Query: 283  KKAAH 287
            ++ +H
Sbjct: 1827 ERRSH 1831



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 53/218 (24%), Positives = 70/218 (32%), Gaps = 28/218 (12%)

Query: 88   PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDT 147
            P E +     + S +      H      + H   +    SP   RH +P         + 
Sbjct: 1705 PSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSER 1764

Query: 148  PDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDT---SPPRRARH---DSPDPS 201
               SP   RH +P           S  SP  R  H  S+    SP  R+RH   +    S
Sbjct: 1765 SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRS 1824

Query: 202  PPRRPQHNSSGDCQKATDSDLSSPRHKQ--SP------------GHQDSDSDLSPPRNRP 247
            P  R  H S     +       SP  K   SP            GH  S      P  R 
Sbjct: 1825 PSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSER- 1883

Query: 248  RHRSSD-------SDLSPPRRRQRTKSSDSDLSPPRRS 278
             HRS         S+ S     +RT+ S S++ P R S
Sbjct: 1884 SHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPS 1921


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 80/412 (19%), Positives = 153/412 (37%), Gaps = 47/412 (11%)

Query: 24  VDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEF 83
           V R + +G +  +++P  GG+     R  +      A    K EK+++E + +    A  
Sbjct: 379 VHRCAPAGERGERRKPNAGGSPAPVRRRPE------ASPVQKKEKKDKERENEKEKSAL- 431

Query: 84  VDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPR-- 141
              R   +K+ ++  +S + +L      +L      R  +P +S  R     P P P   
Sbjct: 432 --ARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHT 489

Query: 142 ------KDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSP--PRRA 193
                   R  T  P  R  R +    SP      D   S  RR  ++    +P  P  +
Sbjct: 490 LPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSK-RRASNEKESAAPASPAPS 548

Query: 194 RHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSD 253
              SP P+PP++ Q  +      A  +   +P    +P         S P      R   
Sbjct: 549 PAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTP---------SKPMAGTTDREEA 599

Query: 254 SDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQ 313
           + L   +RRQ  +  + +    R      K+                  RE+Q  +E + 
Sbjct: 600 TRLLAEKRRQAREQREREEQERRLQAERDKR-----------------MREEQLAREAEA 642

Query: 314 ETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQ 373
                EAE +  E     +  +    + ERL+++++  +   R+E   Q  +     +QQ
Sbjct: 643 RAER-EAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQ 701

Query: 374 QQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKN 425
           +Q  ++  K +++ + R    E  +   ++  +E +   +  +  KA E ++
Sbjct: 702 EQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARS 753



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 46/189 (24%), Positives = 73/189 (38%), Gaps = 7/189 (3%)

Query: 188 SPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDL-SSPRHKQSPGHQDSDSDLSPPRNR 246
           +PP        DPSPP  P      D    T   + ++   KQ P   +S S    PR  
Sbjct: 21  TPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPA 80

Query: 247 PRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQ 306
           P    S S  +  R          D  PPRRS  P   A        T   +       +
Sbjct: 81  PPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHK 140

Query: 307 ELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKG 366
             KE+ +E   + A     + V+ +K  + + L+ ++L++RR+     E   L A+  + 
Sbjct: 141 LAKERREERAKYLAA---KKAVWLEKEEKAKALREKQLQERRRR---LEEQRLKAEQRRA 194

Query: 367 LAQSRQQQQ 375
             + RQ+Q+
Sbjct: 195 ALEERQRQK 203



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 57/233 (24%), Positives = 94/233 (40%), Gaps = 31/233 (13%)

Query: 148 PDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDS----PDPSPP 203
           P+P P      +P P P+     D+    P  +++ +S    P      S    P P+PP
Sbjct: 23  PEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPP 82

Query: 204 RRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQ 263
           +    +S    +  T   +  PR  + P      S  + P       +SD   SPP +++
Sbjct: 83  QEESPSSEAKSRGPTPPAM-GPRDARPPRRSSQPSPTAVP-------ASD---SPPTKQE 131

Query: 264 RTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQ 323
             K+ +       R +   K     Y  AK  + L + + + + L+E+  +      E Q
Sbjct: 132 VKKAGERHKLAKERREERAK-----YLAAKKAVWL-EKEEKAKALREKQLQERRRRLEEQ 185

Query: 324 YAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWG--KGLAQSRQQQ 374
                 R K+ ++R    ER  QR+K EK+ ER E   Q    K  A+ RQQ+
Sbjct: 186 ------RLKAEQRRAALEER--QRQKLEKNKERYEAAIQRSVKKTWAEIRQQR 230


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 64/241 (26%), Positives = 98/241 (40%), Gaps = 43/241 (17%)

Query: 11  EYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA------ISTT 64
           EY++R  S  +       E GRK++K R K  G       + D +           +S  
Sbjct: 113 EYIEREESDGEY-----DEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKY 167

Query: 65  KLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTP 124
           KL+++E+EDD DL        E  +  K+    RS +K +           + H R  + 
Sbjct: 168 KLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSR-----------SSHSRSSSR 216

Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT------SPPR 178
            SSP   R      S  + R  +   S  R+R  + + S  RG++  S +      S PR
Sbjct: 217 SSSPSSSR------SRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPR 270

Query: 179 RIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQK-ATDSDLSSPRHKQSPGHQDSD 237
           +  + SS +SP R  +          R + +SSGD +K  T S     RH+ S G   S 
Sbjct: 271 KRSYSSSSSSPERNRKRS--------RSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSG 322

Query: 238 S 238
           S
Sbjct: 323 S 323



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 31/120 (25%), Positives = 45/120 (37%), Gaps = 3/120 (2%)

Query: 178 RRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSD 237
           RR R  S  +     +R  SP  S  R    + S    ++     S  R +       S 
Sbjct: 200 RRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSS 259

Query: 238 SDLSPPRNRPRHRSSDSDLSPP---RRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKT 294
           S      + PR RS  S  S P   R+R R++SS S     RR++    +  H  S   +
Sbjct: 260 SRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSS 319



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 32/157 (20%), Positives = 56/157 (35%), Gaps = 7/157 (4%)

Query: 219 DSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRS 278
           D DLS  ++K      + D+DLS   N       DS+     RR R+KS  S      RS
Sbjct: 161 DEDLS--KYKLDEDEDEDDADLSK-YNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRS 217

Query: 279 QPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRN 338
             P    +   S +++        R     + + + + +  +   +  +     S RKR+
Sbjct: 218 SSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGS----SSPRKRS 273

Query: 339 LKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQ 375
                    R  ++   R        K   +SR  ++
Sbjct: 274 YSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPER 310


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 93/412 (22%), Positives = 151/412 (36%), Gaps = 52/412 (12%)

Query: 25  DRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEK-----EEEEDDGDLPV 79
           +R     R   KK  +P G  G G      +++ T  ST K +       +E+ D   P 
Sbjct: 182 ERSDSQPRNLSKKSYRPPGGSGIGR---SSELAVTP-STAKCQTPTGIPSKEKSDNPSPS 237

Query: 80  VAEFVDER-----PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHG 134
            +  V        P   K       S++ K    +N+    +R   H +   SPRR R G
Sbjct: 238 SSRKVKSYGQMIIPSREKSYSPTEMSSRVK---SYNQASTRSRPQSH-SQSRSPRRSRSG 293

Query: 135 TPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRAR 194
           +   +  + R  +   +  RAR  T      +  RH    S  +    + S T  PRR R
Sbjct: 294 SQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRT--PRRGR 351

Query: 195 HDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQ--------DSDSDLSPPRNR 246
             +   +P +   H+ S    K  D   SS   K+S   Q        D     SP + R
Sbjct: 352 SHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKAR 411

Query: 247 PRHRSSDSDLSPPRRRQRTKSSDSDLSPPR---------RSQPPGKKAAHMYSGAKTGLV 297
            R RS     +  R R R+ +   D S  R         RS+ P K   H  S +++   
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDH--SRSRSPNK 469

Query: 298 LTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERD 357
             D  R +   KE+D   +   +         +++  R+     +  + R+      ERD
Sbjct: 470 ARDRSRSRSPSKERDHSQLGSPS---------KERDHRRSRSPSKERQCRQSRSSSKERD 520

Query: 358 ELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGD 409
               +  +  ++ RQ++Q+     KE  +  +R   +E   R  R   +E D
Sbjct: 521 H---RRSRSPSKERQRRQS-RSPNKERDRSQSRSPSEEREHRQSRSPSKERD 568



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 67/286 (23%), Positives = 102/286 (35%), Gaps = 30/286 (10%)

Query: 92  KQMEAFRSSAKWKLLGGHNEDLPSNR--HFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPD 149
           K  +  RS + +K         P+    H R  +P+ +  R R  +  PS  +D      
Sbjct: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR--SRSPSKERDHSQLGS 490

Query: 150 PSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHN 209
           PS  R    +  PS  R  R    +S  R  R   S +   +R +  SP+    R     
Sbjct: 491 PSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDR----- 545

Query: 210 SSGDCQKATDSDLSSPRHKQSPG-HQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSS 268
                Q  + S+    R  +SP   +D     SP + R R +S  S       R R+ + 
Sbjct: 546 ----SQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNK 601

Query: 269 DSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETV 328
            S  S PR S    K+ AH  S ++T     +  + +   KE D              TV
Sbjct: 602 QSGYSRPRAS---SKEKAH--SRSRTPSKEGNHSQSRTSSKESDPS----------QSTV 646

Query: 329 FRDKSGRKRNLKLERLEQRRKAEKDSERD-ELYAQWGKGLAQSRQQ 373
            R    ++   +   L Q R   K S      +   G+ L+Q   Q
Sbjct: 647 PRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQ 692



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/231 (25%), Positives = 84/231 (36%), Gaps = 34/231 (14%)

Query: 70  EEEDDGDLPVVAEFVDER----PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPD 125
           +E D   L   ++  D R    P + +Q    RSS+K               H R  +P 
Sbjct: 481 KERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSK------------ERDHRRSRSP- 527

Query: 126 SSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSS 185
            S  R R  +  P+  +DR  +  PS  R    +  PS  R  R     S  R  R   S
Sbjct: 528 -SKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRS 586

Query: 186 DTSPPRRARHDSPDP-SPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPR 244
            +     +R  SP+  S   RP+ +S       + +      H QS     + S  S P 
Sbjct: 587 SSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSR----TSSKESDPS 642

Query: 245 NRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTG 295
                RS D   SP R         S LS   +++ P K ++H  S   +G
Sbjct: 643 QSTVPRSPDWKRSPTRT--------SSLS---QNRTPSKTSSHSPSTFPSG 682



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 40/171 (23%), Positives = 59/171 (34%), Gaps = 18/171 (10%)

Query: 126 SSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSS 185
           SSP+R    +   +P      T DP P  +   T   +P R        + P   R+   
Sbjct: 2   SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSL----VPTKPATSRNSVM 57

Query: 186 DTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRN 245
             S  +  +  S   +P  RP   S    +  T S +S+             S  S  R 
Sbjct: 58  SPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKA------SKASDVRC 111

Query: 246 RPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGL 296
             R  +     +P RR  R     S    P R+  PG+   H   GA+ G+
Sbjct: 112 HQRRGTHSRGRTPGRRGSR-----SSKRSPSRASTPGRIRTH---GARPGM 154



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 46/210 (21%), Positives = 74/210 (35%), Gaps = 43/210 (20%)

Query: 123 TPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRH 182
           TP S  +  R G     PR    +  D  PR     +  P    G    S+ +       
Sbjct: 160 TPTSQQKGSR-GKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAK 218

Query: 183 DSSDTSPPRRARHDSPDPSPPRRPQ--------------------------HNSSGDCQK 216
             + T  P + + D+P PS  R+ +                          + +S   + 
Sbjct: 219 CQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRP 278

Query: 217 ATDSDLSSPRHKQSPGHQDSDSDL---SPPRN--RPRHRSSDSDLSPPRRRQRTKS---- 267
            + S   SPR  +S   + + S +   S  RN  R R R+    LS   R  +++S    
Sbjct: 279 QSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKG 338

Query: 268 -SDSDLSPPRR------SQPPGKKAAHMYS 290
            S +    PRR      S+ P K+ +H +S
Sbjct: 339 KSQNQSRTPRRGRSHNWSRNPSKERSHSHS 368


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 82/380 (21%), Positives = 152/380 (40%), Gaps = 21/380 (5%)

Query: 65  KLEKEEEEDDGDLPVVAEFVDER-PEEVKQMEAFRSSAKWKLLGGHNE--DLPSNRHFRH 121
           K  +EE E + D     +  D+R P + +     R +   + L    +  D    R +  
Sbjct: 428 KDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR 487

Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIR 181
           DT +S   R    T D    +DR         R     P+ S   G  H  + S    IR
Sbjct: 488 DTKESRDPRDSRSTRDAHDYRDREGR---DTHRKEDTYPEESRSYGRNHLREESSRTEIR 544

Query: 182 HDSSDTSPP--RRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDS--D 237
           ++S + S    R  R        P  P+  S G      DS  S+  +  S   + S  +
Sbjct: 545 NESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPE 604

Query: 238 SDLSPPR-NRPRHRSSDSDLSPPRRRQR-TKSSDSDLSPPRRSQPPGKKAAHMYSGAKTG 295
            D  P R NR + R S  +     R +R  +  D   S P R Q    +        +  
Sbjct: 605 RDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664

Query: 296 LVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR---RKAEK 352
           +   D +R+++  +E+D+E        +  E     +  ++R L+ ER  +R   R+ E+
Sbjct: 665 VDRVDDRRDERA-RERDRERERDRERERERERERDREREKERELERERAREREREREKER 723

Query: 353 DSERD-----ELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE 407
           D ERD     +   +  +   + +++++  E+  +E ++   R  + E      RE+++E
Sbjct: 724 DRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKE 783

Query: 408 GDPMANFIKKNKAKENKNKK 427
            +   ++  K+K ++++ +K
Sbjct: 784 RERQRDWEDKDKGRDDRREK 803



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/392 (22%), Positives = 139/392 (35%), Gaps = 55/392 (14%)

Query: 88  PEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRH-----DTP-----DSSPRRVRHGTPD 137
           P+  +     RS  + K  G H+ +  S  H R      DT      +   R  R    D
Sbjct: 382 PQRKQSPPRHRSPMREK--GRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQD 439

Query: 138 PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDS 197
            S  +D  D  +P   R R D  D    R  R   D    R +R  S DT   R  R DS
Sbjct: 440 QSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPR-DS 498

Query: 198 PDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPG--HQDSDSDLSPPRNRPRHRSSDSD 255
                    +     D  +  D   + P   +S G  H   +S  +  RN  R+ S    
Sbjct: 499 RSTRDAHDYRDREGRDTHRKED---TYPEESRSYGRNHLREESSRTEIRNESRNESRSEI 555

Query: 256 LSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQET 315
            +    R R +  +      R S+     +    S             E+    E+D   
Sbjct: 556 RNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRD 615

Query: 316 MAFEAEFQ--YAETVFRDKSGRK-----------RNLKL---ERLEQRRKAEKDSERDEL 359
            A ++ F+  + E   RD   R            RN +L   ER E+RR    D  RDE 
Sbjct: 616 QARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDER 675

Query: 360 YAQWGKGLAQSRQQQQNVE-------DAMKEMQKPLARYID-------------DEDLDR 399
             +  +   + R++++  E       +  +E+++  AR  +             D D DR
Sbjct: 676 ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDR 735

Query: 400 MLREQEREGDPMANFIKKNKAKENKNKKVRPR 431
             RE+ERE D      ++ + +E + ++ R R
Sbjct: 736 E-RERERERDREKEREREREERERERERERER 766



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 88/448 (19%), Positives = 153/448 (34%), Gaps = 64/448 (14%)

Query: 11  EYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEE 70
           EY +   S  D   DR    GR RR  R        +  R + D       S    E  +
Sbjct: 435 EYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRD 494

Query: 71  EEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRR 130
             D        ++ D    +  + E             H  +  S    R+++ + S   
Sbjct: 495 PRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSE 554

Query: 131 VRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPP 190
           +R+     S R    + P+   R +R    D        HDS  +   R  +   D  P 
Sbjct: 555 IRNDRMGRS-RGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWET---RSSYPERDRYPE 610

Query: 191 RRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDS-------DLSPP 243
           R  R  + D S  RR       D ++      S  RH+      + D        D    
Sbjct: 611 RDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDD 670

Query: 244 RNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQR 303
           R   R R  D +    R R+R +  + D    +  +   ++A                +R
Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKERELERERAR---------------ER 715

Query: 304 EQQELKEQDQETMAFEAEFQYAETVFRDKSG---RKRNLKLERLEQRRKAEKDSERDELY 360
           E++  KE+D+E               RD+     R+R  + +R ++R +  ++ ER+   
Sbjct: 716 EREREKERDRERD-------------RDRDHDRERERERERDREKEREREREERERER-- 760

Query: 361 AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKA 420
               +   +  ++++   +  +E  K   R  D ED D+  R+  RE        K+ + 
Sbjct: 761 ----ERERERERERERERERARERDKERERQRDWEDKDKG-RDDRRE--------KREEI 807

Query: 421 KENKN-------KKVRPRYSGPAPPPNR 441
           +E++N       +K + RY     P  R
Sbjct: 808 REDRNPRDGHDERKSKKRYRNEGSPSPR 835



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 67/351 (19%), Positives = 128/351 (36%), Gaps = 28/351 (7%)

Query: 55  DVSWTAISTTKLEKEEEEDDGDL-PVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDL 113
           D+++  +    LE + ++   +L  +  E +++R E + + E      + KL    +   
Sbjct: 155 DINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRK 214

Query: 114 PSNRHFRHDTPDSSP--RRVRHGTPDPSPRKD--RHDTPDPSPRRARHDTPDPSPLR--- 166
            S    R  +P SS   ++ R  +   SP  D  R+   + S ++       P P+    
Sbjct: 215 SSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDI 274

Query: 167 --GARHDSDTSPPRRIRHDSSDTSPP------RRARHDSPDPSPPRRPQHNSSGDCQKAT 218
             G ++        RI   + D          +R + D P  + P    H+       ++
Sbjct: 275 ALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSS 334

Query: 219 DSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRS 278
            S   S   + SP         SP R R    S    L+PP RR  +      LS P+R 
Sbjct: 335 SSQSGSSIQRHSP---------SPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRK 385

Query: 279 QPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRN 338
           Q P +  + M    +     T    +++  + +D        +    E  +       R+
Sbjct: 386 QSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRD 445

Query: 339 LKLERLEQRRKAEKDSE--RDELYAQWGKGLAQSRQQQQNVEDAMKEMQKP 387
            + +R  +  +  +D+   RD    +  + +  SR+ +    D  KE + P
Sbjct: 446 HRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDT-KESRDP 495



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 48/243 (19%), Positives = 86/243 (35%), Gaps = 33/243 (13%)

Query: 250 RSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK 309
           RS +      R R + K  D D  P +R+           S         DI+  ++   
Sbjct: 76  RSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTP 135

Query: 310 EQDQETMAFEAE----------FQYAETVFRDKSGRKRNLKLERLEQRR--KAEKDSERD 357
           E ++E + +E            + Y   +  +   +K   +L +LEQ    K E+   + 
Sbjct: 136 ESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKK 195

Query: 358 ELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKK 417
           E+  +  +         +    + K    P +     +D     R+      P+ +  ++
Sbjct: 196 EVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKD-----RKTSAVSSPLLD--QQ 248

Query: 418 NKAKENKNKKVRPRYSGPAPP-PNRFNIWPGYR-------------WDGVDRSNGFEQKR 463
             +K N++KK  PR   P PP P    +   Y+              DG DR   FE++R
Sbjct: 249 RNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQR 308

Query: 464 FAR 466
             R
Sbjct: 309 EKR 311



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 61/287 (21%), Positives = 100/287 (34%), Gaps = 33/287 (11%)

Query: 112  DLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHD 171
            D    R    +  +    R R    +    ++R    D    R R D  D    R  R +
Sbjct: 744  DREKEREREREERERERERERERERERERERERARERDKERERQR-DWEDKDKGRDDRRE 802

Query: 172  S--DTSPPRRIRHDSSDTSPPRRARHD---SPDPSPPRRPQHNSSGDCQKATDSDLSSPR 226
               +    R  R    +    +R R++   SP  SP RR +H+   D   + D      R
Sbjct: 803  KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHR 862

Query: 227  HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAA 286
                         LS     P H + D       R+ R K  D         +P  K+++
Sbjct: 863  LLSQVVRPQESRSLS-----PSHLTED-------RQGRWKEED--------RKPERKESS 902

Query: 287  HMY--SGAKTGLVLTDIQREQQELKEQDQ---ETMAFEAEFQYAETVFRDKSGRKRNLKL 341
              Y     K  +   D QREQ E+ E  +   + +    + +  ET  R     K+  K+
Sbjct: 903  RRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKI 962

Query: 342  ERLEQRRKAEKD--SERDELYAQWGKGLAQSRQQQQNVEDAMKEMQK 386
            ++   ++K E D   ER  +      G   S ++ Q  +   K+ +K
Sbjct: 963  QKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKK 1009



 Score = 32.3 bits (72), Expect = 0.99
 Identities = 67/296 (22%), Positives = 110/296 (37%), Gaps = 36/296 (12%)

Query: 130  RVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSP 189
            +++ G P  S   DR D+   S RR+  ++      R    DS      R R++      
Sbjct: 1253 QLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHD--RE 1310

Query: 190  PRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRH 249
              R R D+      R+ + +   D     + D    R ++    +D   DL   R R R 
Sbjct: 1311 RERERRDT------RQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLD--RERERL 1362

Query: 250  RSSDSDLSPPRRRQRTKSSDSDLSPPR-RSQPPGKKAAHMYSGAKTGLVLTDIQREQQEL 308
             S   +    R R RT  S    S  R  ++  G+    + S ++  L L D +R  ++L
Sbjct: 1363 ISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLAL-DKERMDKDL 1421

Query: 309  --------KEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELY 360
                      + + T + EA    ++       G       E +        D E DE+ 
Sbjct: 1422 GSVQGFEETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEPI-------SDDELDEIL 1474

Query: 361  AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIK 416
            A    G A+ R+ QQ+ E    +M  PL   ID +    M +  +   +P A  +K
Sbjct: 1475 A----GDAEKREDQQDEE----KMPDPL-DVIDVDWSGLMPKHPKEPREPGAALLK 1521


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 54/272 (19%), Positives = 111/272 (40%), Gaps = 35/272 (12%)

Query: 178 RRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSD 237
           RR R    +    RR R    +    R  +     + ++  D D +  R +     +D D
Sbjct: 309 RRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRD 368

Query: 238 SDL--SPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTG 295
            D   S  RN+ R RS +      R R+R +  + +    R  +   ++        +  
Sbjct: 369 RDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE-- 426

Query: 296 LVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSE 355
               D +R+++E +E   E    E + +  E  +++   R +N ++   ++ R+ EK++E
Sbjct: 427 ---KDKKRDREEDEEDAYERRKLERKLREKEAAYQE---RLKNWEIRERKKTREYEKEAE 480

Query: 356 RDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDED---------LDRMLREQER 406
           R+E             ++++ +    K +++ L  Y DD D         L + LR++E+
Sbjct: 481 REE-------------ERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREK 527

Query: 407 EGDPMANFIKKNKAKENKNKKVRPRYSGPAPP 438
           E   M    +  K ++ + +++R R      P
Sbjct: 528 E---MEADERDRKREKEELEEIRQRLLAEGHP 556



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 47/189 (24%), Positives = 82/189 (43%), Gaps = 31/189 (16%)

Query: 251 SSDSDLSPPRRRQRTKSSD-------SDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQR 303
           S +SD S PR++++ K  D       + L P          A  M    K  L+  +I +
Sbjct: 226 SQESD-SHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEED-KRDLISREISK 283

Query: 304 EQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQW 363
            +   K+ ++E    E E Q  E     K  R+R  + ER  +RR+ E++ ER+    + 
Sbjct: 284 FRDTHKKLEEEKGKKEKERQEIE-----KERRERERERERERERRERERERERER---ER 335

Query: 364 GKGLAQSRQQQQNVE-DAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKE 422
            K   + R+++++ + D  KE  +   R  D +      R++ER  D       +NK + 
Sbjct: 336 EKEKERERERERDRDRDRTKERDRDRDRERDRD------RDRERSSD-------RNKDRS 382

Query: 423 NKNKKVRPR 431
              +K R R
Sbjct: 383 RSREKSRDR 391


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 59/280 (21%), Positives = 111/280 (39%), Gaps = 37/280 (13%)

Query: 169 RHDSDTSPPRR---IRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSP 225
           R  S  SP RR     H  +D     R R    +    RR +  +  +  +  +      
Sbjct: 30  RPGSQESPRRRGLGQAHKDADGDDRERNRQKERER---RREKRQTERETDRKRERRREKD 86

Query: 226 RHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKA 285
           RH++   H++   D    R + R R +D +    R RQR K  +      R ++  G++ 
Sbjct: 87  RHRKRDRHRERQRD----REKERERQTDRE----RDRQREKERNRQKERERETEREGERG 138

Query: 286 AHMYSGAKTGLVLTDIQREQQELKEQDQE-TMAFEAEFQYAETVFRDKSGRKRNLKLERL 344
                        TD QRE++  ++ ++E     + E Q      R K   +   + ER 
Sbjct: 139 RDRQ---------TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189

Query: 345 EQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVE-------------DAMKEMQKPLARY 391
           E+ R+ EK+++ ++ +++ G+   + R+ +   E                +E +K   R 
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERE 249

Query: 392 IDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVRPR 431
              E      +E+ERE D   +  ++ K +E +  + R R
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 68/337 (20%), Positives = 131/337 (38%), Gaps = 28/337 (8%)

Query: 98  RSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRK-DRHDTPDPSPRRAR 156
           + S + + LG  ++D   +   R+   +   RR +  T   + RK +R    D   +R R
Sbjct: 34  QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93

Query: 157 HDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQK 216
           H        R  + D +    R+   +        R R    +    R  +        +
Sbjct: 94  H--------RERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD----R 141

Query: 217 ATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPR--RRQRTKSSDSD-LS 273
            TD      R + +   ++  +D    R   R+R  + +    R  RR+R +  + +  +
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKT 201

Query: 274 PPRRSQPPGKKAAHMYSGAKTGLV-LTDIQREQQELKEQDQETMAFEAEFQYAETVFRDK 332
             R S+   ++     +  +T     TD +R++Q   E+++E  A        ET  RDK
Sbjct: 202 EDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETE-RDK 260

Query: 333 SGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYI 392
             R+R    +R   RR+ E++ + D           Q R ++    +  +E Q+   R  
Sbjct: 261 E-RERERDRDRDRDRRQKERERQTDR--------KRQRRTERDRETERKRERQRERERER 311

Query: 393 DDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVR 429
           +        RE+ERE +      ++++ KE + K+ R
Sbjct: 312 ERNRKRERERERERERERQRE-TERDREKERERKRKR 347



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 54/242 (22%), Positives = 104/242 (42%), Gaps = 35/242 (14%)

Query: 192 RARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRS 251
           R R    +    R+ Q +   D Q+ T+ +    R KQ+   + S+ +    + R R R 
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTERE----REKQAERERASERETERDKERERERD 267

Query: 252 SDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQ 311
            D D     RRQ+ +   +D    RR++   +               T+ +RE+Q  +E+
Sbjct: 268 RDRDRD---RRQKERERQTDRKRQRRTERDRE---------------TERKRERQRERER 309

Query: 312 DQE-TMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQS 370
           ++E     E E +      R +   +   K    +++R+ E D ER+    Q G+   + 
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR---QTGR---EG 363

Query: 371 RQQQQNVEDAMKEMQKPLARYIDDEDLDR-MLREQEREGDPMANFIKKNKAKENKNKKVR 429
           R+Q +   +  +E  +  AR  ++ + DR   R++ERE        +K++  + + +K R
Sbjct: 364 RRQAERERERERERDRQSAREREERERDRDRDRQKERERQ-----TEKDRDGQRETEKQR 418

Query: 430 PR 431
            R
Sbjct: 419 ER 420



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 63/315 (20%), Positives = 118/315 (37%), Gaps = 48/315 (15%)

Query: 130 RVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSP 189
           R R    + + +K+R    +   RR R    +       RH        R R   ++T  
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE- 223

Query: 190 PRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRH 249
             R R    +    R+ +       ++   S+  + R K+    +D D D    R + R 
Sbjct: 224 --RKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR-RQKERE 280

Query: 250 RSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK 309
           R +D      R+RQR    D +    R  Q                    + +RE++  +
Sbjct: 281 RQTD------RKRQRRTERDRETERKRERQ-------------------RERERERERNR 315

Query: 310 EQDQETMAFEAEFQYAETVFRDKS-----GRKRNLKLER-------LEQRRKAEKDSERD 357
           ++++E    E E +      RD+       RKR  +++R        E RR+AE++ ER+
Sbjct: 316 KRERERER-ERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERE 374

Query: 358 ELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYID-DEDLDRMLREQEREGDPMANFIK 416
                  +    +R++++   D  ++ QK   R  + D D  R   +Q        +   
Sbjct: 375 R-----ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERG 429

Query: 417 KNKAKENKNKKVRPR 431
           + + +E + +K R R
Sbjct: 430 RERGREREKQKGRER 444



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 63/336 (18%), Positives = 113/336 (33%), Gaps = 25/336 (7%)

Query: 25  DRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFV 84
           DR SE GR+R ++R        K     + D         K E+E E+            
Sbjct: 203 DRHSERGRERERERETETETERKRQTDRERD------RQRKTEREREKQAERERASERET 256

Query: 85  DERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPR---RVRHGTPDPSPR 141
           +   E  ++ +  R   + +       D    R    D      R   R R    + + +
Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316

Query: 142 KDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPS 201
           ++R    +    R R    D    R  +    T   R  R+  +     R+A  +     
Sbjct: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRE-RNRQTGREGRRQAERERERER 375

Query: 202 PPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRR 261
              R       + ++  D D    R +Q+   +D D      + R R +  +S+    R 
Sbjct: 376 ERDRQSAREREERERDRDRDRQKERERQT--EKDRDGQRETEKQREREKDRESERGRERG 433

Query: 262 RQRTKSSDSDLSPPRRSQPPG---KKAAHMYSG-----AKTGLVLTDIQREQQEL--KEQ 311
           R+R K    +    R++       +K + +Y       A++G+V +D  R  + +  K  
Sbjct: 434 REREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSS 493

Query: 312 DQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQR 347
            ++  A    F +       K+ R R     R E R
Sbjct: 494 PEDPKAASTRFPWGRPA---KASRGRVAGRRRWEPR 526


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo
           sapiens]
          Length = 2365

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 57/220 (25%), Positives = 81/220 (36%), Gaps = 17/220 (7%)

Query: 112 DLPSNRHFRHDTPD-SSPRRVRHGTPDPS------PRKDRHDTPDPSPRR------ARHD 158
           D P     + D P  SSP R     P  S      PR  R  +P+ + R       A+ D
Sbjct: 475 DNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD 534

Query: 159 TPDPS-PLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKA 217
            P  S P R AR +  TS  +R    +S TS P RA  D+P  S  +R    +S   +  
Sbjct: 535 NPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAT 594

Query: 218 TDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRR 277
            D+  +S   + +P    + S     R+ PR   +  D        RT   DS  +   R
Sbjct: 595 RDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCAR 654

Query: 278 SQPPGKKAAH---MYSGAKTGLVLTDIQREQQELKEQDQE 314
              P   + +        +T   L D  R     +   QE
Sbjct: 655 RDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQE 694



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 39/136 (28%), Positives = 56/136 (41%), Gaps = 6/136 (4%)

Query: 139 SPRKDRHDTPDPSPRRARHDTPDPS-PLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDS 197
           SP +   D P  S   A+ D P  S P R  R +  TS  +R    +S TS P RA  D+
Sbjct: 419 SPNRATRDNPRTSC--AQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDN 476

Query: 198 PDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSD-- 255
           P  S  +R    +S   +   D+  +S   + +P    + S     R+ PR   +  D  
Sbjct: 477 PRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNP 536

Query: 256 -LSPPRRRQRTKSSDS 270
             S P R  R   + S
Sbjct: 537 RASSPNRAARDNPTTS 552



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 48/177 (27%), Positives = 69/177 (38%), Gaps = 17/177 (9%)

Query: 111 EDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPS-----PRRARHDTP----- 160
           ED P     + +TP +S         +P     + D P  S     P+R    TP     
Sbjct: 327 EDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQD 386

Query: 161 DP---SPLRGA-RHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQK 216
           DP   SP R   R +S TS  +R    +S TS P RA  D+P  S  +R    +S   + 
Sbjct: 387 DPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRA 446

Query: 217 ATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSD---LSPPRRRQRTKSSDS 270
             D+  +S   + +P    + S     R+ PR   +  D    S P R  R   + S
Sbjct: 447 TRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTS 503



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 55/198 (27%), Positives = 75/198 (37%), Gaps = 40/198 (20%)

Query: 112 DLPSNRHFRHDTPD-SSPRRVRHGTPDPS------PRKDRHDTPDPSPRR------ARHD 158
           D P     + D P  SSP R     P  S      PR  R  +P+ + R       A+ D
Sbjct: 573 DNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD 632

Query: 159 TPDPS-PLRGARHDSD------------TSPPRRIRHDSSDTSPPRRARHDSPDPSPPRR 205
            P  S P R  + DS             +SP R I+ ++  TS    A  D+P  S P R
Sbjct: 633 NPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTS---CALRDNPRASSPSR 689

Query: 206 --PQHNSSGDCQKATDSDLSSP-RHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRR 262
              Q N    C +  D   SSP R  Q    + S +    PR   R+R+         +R
Sbjct: 690 TIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTI--------QR 741

Query: 263 QRTKSSDSDLSPPRRSQP 280
              ++S +    PR S P
Sbjct: 742 DNPRTSCAQRDNPRASSP 759



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 60/226 (26%), Positives = 85/226 (37%), Gaps = 41/226 (18%)

Query: 88   PEEVKQMEA-FRSSAKWKLLGGHNEDLPSNRHFRHDTPDSS--------PRRVRHGTPDP 138
            P   KQ E  + S A     G   +    +R  +HD P SS        P R    + +P
Sbjct: 924  PSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNP 983

Query: 139  SPRK-DRHDTPD-PSPRRARHDTPDPSPLRGA----RHDSD--TSPPRRIRHDSSDTSP- 189
              +   R  +P  P+   A   +P+PS    A      D+   +SPPR ++HD     P 
Sbjct: 984  GHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPE 1043

Query: 190  PRRARHDSPDPSPPRRPQHNSSG--DCQKATDSDLSSPRHKQ------SPGHQDSDSDLS 241
            PR    + P   PP  P     G  D  +A+    S PRH Q       P   D++    
Sbjct: 1044 PRAPESEPPHHEPPYIPPAVCIGHRDAPRAS----SPPRHTQFDPFPFLPDTSDAEHQCQ 1099

Query: 242  PPRNRP---------RHRSSDSDLSPPRRRQRTKSSDSDLSPPRRS 278
             P++ P          +R +    SPPR+         DL  PR S
Sbjct: 1100 SPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDL--PRAS 1143



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 74/337 (21%), Positives = 119/337 (35%), Gaps = 58/337 (17%)

Query: 139  SPRKDRHDTPDPSPRRARHDTPDPS-----PLRGARHDSDTSP-PRRIRHDS--SDTSPP 190
            +PR        P P     D P  S     P   + H+    P P  I H    S +SPP
Sbjct: 1119 APRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPP 1178

Query: 191  RRARHDSPDPSPP-RRPQHNSSGDCQKATDSDLSSPR--HKQSPGHQDSDSDLSPPRNRP 247
            R+A    P+PS   + P   S      +TDS   SP    +   GH+D+    SPPR+ P
Sbjct: 1179 RQA----PEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPP 1234

Query: 248  RHRS-------------SDSDLSPPRRRQRTKSSD----SDLSPPRR--SQPPGKKAAHM 288
               +             S     P   R   +  +    +DL PPRR   + PG +A   
Sbjct: 1235 SDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCS 1294

Query: 289  YSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRR 348
              G        +++R   + + + +   AF+A+            GR +     + +  R
Sbjct: 1295 SGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQ----------DEGRSQQPSQGQSQLLR 1344

Query: 349  KAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREG 408
            +    +   ++     K    +R+ Q          ++P        + DR L     +G
Sbjct: 1345 RQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRP--------EGDRQL-----QG 1391

Query: 409  DPMANFIKKNKAKENKNKKVRPRYSGPAPPPNRFNIW 445
             P+       +  E + +  RP  SG A P     +W
Sbjct: 1392 SPLPPRTSA-RTPERELRTQRPLESGQAGPRQPLGVW 1427



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 43/161 (26%), Positives = 60/161 (37%), Gaps = 22/161 (13%)

Query: 120 RHDTPDSSPRRVRHGTPDPSPRKD--RHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPP 177
           R D   SSP R    T   +PR    R D P  S R       +P      R +   S P
Sbjct: 703 RDDPRASSPNRT---TQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSP 759

Query: 178 RRI-----------RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPR 226
            R            R D+  TS P RA  D+P  S  +R    +S    +AT  D  +PR
Sbjct: 760 NRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPI-RATQQD--NPR 816

Query: 227 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKS 267
              +   Q+     S  ++ P+   +  D   P   QR ++
Sbjct: 817 ---TCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRT 854



 Score = 29.3 bits (64), Expect = 8.4
 Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 21/121 (17%)

Query: 132  RHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD--TSP 189
            RH   DP P       PD S    +  +P   PL+          P  I +  +   +SP
Sbjct: 1078 RHTQFDPFPF-----LPDTSDAEHQCQSPQHEPLQ-------LPAPVCIGYRDAPRASSP 1125

Query: 190  PRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSP---GHQDSDSDLSPPRNR 246
            PR+A    P+PS   +    +S +    +   L    H  +P   GH+D+ S  SPPR  
Sbjct: 1126 PRQA----PEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQA 1181

Query: 247  P 247
            P
Sbjct: 1182 P 1182


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 44/172 (25%), Positives = 65/172 (37%), Gaps = 8/172 (4%)

Query: 109  HNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGA 168
            H    PS +  RH     SP+  RH T   S + +RH    PS +  +H    PS  +  
Sbjct: 1806 HPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPS-AKTE 1864

Query: 169  RHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPS--PPRRPQHNSSGDCQKATDSDLSSPR 226
            RH   +S  +  +H  S  SP  +    SP  S    R P  + SG   K      S   
Sbjct: 1865 RHSPASSSSKTEKH--SPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPVSPSGRT 1922

Query: 227  HKQ---SPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPP 275
             K    SPG  +    +SP     +H+   +     +    + S  ++  PP
Sbjct: 1923 EKHPPVSPGRTEKRLPVSPSGRTDKHQPVSTAGKTEKHLPVSPSGKTEKQPP 1974



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 58/282 (20%), Positives = 100/282 (35%), Gaps = 27/282 (9%)

Query: 111  EDLPSNR-HFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGAR 169
            ED+P    H  H     S +  RH    PSP+ +RH T   S +  RH  P  SP     
Sbjct: 1795 EDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERH--PPVSPSSKTE 1852

Query: 170  HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQ 229
              S  SP  +    S  +S  +  +H    PS  +  +H+             S+   + 
Sbjct: 1853 KHSPVSPSAKTERHSPASSSSKTEKHSPVSPS-TKTERHSPVS----------STKTERH 1901

Query: 230  SPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMY 289
             P      +D  PP +          +SP R  +R   S S  +   +      K     
Sbjct: 1902 PPVSPSGKTDKRPPVSPSGRTEKHPPVSPGRTEKRLPVSPSGRTDKHQPVSTAGKTEKHL 1961

Query: 290  SGAKTGLVLTDIQREQQELKEQDQETMAFE---AEFQYAETVFRDKSG--RKRNLKLERL 344
              + +G              E+ +ETM+       FQ  +   + K+G    ++ K ++ 
Sbjct: 1962 PVSPSGKTEKQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAKQKQP 2021

Query: 345  EQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQK 386
            +++ K   + E+  +  Q        R+ Q+     +K  Q+
Sbjct: 2022 QEKGKVRVEKEKGPILTQ--------REAQKTENQTIKRGQR 2055



 Score = 32.7 bits (73), Expect = 0.76
 Identities = 35/138 (25%), Positives = 53/138 (38%), Gaps = 19/138 (13%)

Query: 225  PRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSP----PRRRQRTKSSDSDLSPPRRSQP 280
            P+ ++S    D D+D S   + P+H  S  D S          R  SS S+  P      
Sbjct: 2615 PKQEESSSSSDPDADCSVDVDEPKHTGSGEDESGVPVLVTSESRKVSSSSESEP------ 2668

Query: 281  PGKKAAHMYSGAKTGLVLTDIQREQQEL---KEQDQETMAFEAEFQYAETVFRDKSGRKR 337
               + A +  GA +GL+   + R Q         D  +   E +FQ    V   +   K 
Sbjct: 2669 ---ELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQFQ---PVVSKQYTFKM 2722

Query: 338  NLKLERLEQRRKAEKDSE 355
            N   +    + + EKDSE
Sbjct: 2723 NEDTQEEPGKSEEEKDSE 2740


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 84/422 (19%), Positives = 150/422 (35%), Gaps = 85/422 (20%)

Query: 67  EKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDS 126
           E+EEEE++ +     E   E   +  +     S     +  GH+   PS+RH  H+  D 
Sbjct: 194 EEEEEEEEEE-----EASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDD 248

Query: 127 SP---------------------RRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPL 165
                                  R   HG  +     D H   DPS R   H+  D    
Sbjct: 249 DDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEEDD---- 304

Query: 166 RGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRR-PQHNSSGDCQKATDSDLSS 224
                D D S      H +      R+   ++         P H   G   +  D D+S+
Sbjct: 305 ---NDDDDVST--EYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVST 359

Query: 225 PRHKQSPGH--------QDSDSDLS------PPRNRPR-HRSSDSDLS-------PPRRR 262
            R  Q P H        ++ + +++         ++PR H+S + D         P    
Sbjct: 360 ERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHH 419

Query: 263 QRT-KSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAE 321
            R  +  D ++S     Q P  + +H     +TG        ++  +KE           
Sbjct: 420 HRVPREEDEEVSAELGHQAPSHRQSH--QDEETG------HGQRGSIKEMSHHPP----- 466

Query: 322 FQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVED-- 379
                TV +D+S  +++   E  E+        E DE   Q  KG     + Q++ ED  
Sbjct: 467 ---GHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEE 523

Query: 380 ------AMKEMQKPLARYIDDEDLDRMLREQERE-GDPMA-NFIKKNKAKENKNKKVRPR 431
                   +E ++   +  ++E+ D   RE+  E G P++ +  ++ + +E   ++  PR
Sbjct: 524 EGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPR 583

Query: 432 YS 433
           ++
Sbjct: 584 FT 585


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 79/456 (17%), Positives = 156/456 (34%), Gaps = 37/456 (8%)

Query: 2    AAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTAI 61
            A +PP +K+   +   S A+      ++S  K   K P    +  K    V ++    A 
Sbjct: 558  AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617

Query: 62   STTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRH 121
            + + + KEE +   ++    +      EE K  E  +S  K +         P     + 
Sbjct: 618  AKSPV-KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676

Query: 122  DTPDSSPRRVRHGTPDP--SPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRR 179
                 SP +    +P+   SP K+   +P+ +    + +   P   +    +   +P + 
Sbjct: 677  PEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA 736

Query: 180  IRHDSSDTSPPRRARHD---------SPDPSPPRRPQHNSSGD-----CQKATDSDLSSP 225
                  +   P +A+           SP+   P + +  S  D      +     ++ SP
Sbjct: 737  KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP 796

Query: 226  RHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKA 285
               +SP  +D+    +P +  P+     S +    + Q  K  +          P   K 
Sbjct: 797  EKAKSPLKEDAK---APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT 853

Query: 286  AHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKS-----GRKRNLK 340
                   K      +  + + E K++       E++ +  +    DK       ++   K
Sbjct: 854  EEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAK 913

Query: 341  LERLEQRRKAEK---------DSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARY 391
            +E  E  +  EK         D++  E      K  A   ++    E A K  +KP    
Sbjct: 914  VEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEA 973

Query: 392  IDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKK 427
               ED   + +E  +   P A   +K+ + + K+ K
Sbjct: 974  KAKEDDKTLSKEPSK---PKAEKAEKSSSTDQKDSK 1006



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 70/393 (17%), Positives = 145/393 (36%), Gaps = 44/393 (11%)

Query: 60  AISTTKLEKEEEEDDGDLPVVAEFVDER----PEEVKQMEAFRSSAKWKLLGGHNEDLPS 115
           A S  K  K   +++   P  A+  ++     P EVK  E  +S AK +         P 
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568

Query: 116 NRHFRHDTPDSSPRRVRHGTPD----PSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHD 171
               +      SP + +    +    P+  K       P    A+      SP++     
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVK----- 623

Query: 172 SDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSP 231
            +   P  ++      SP +           P + +  S    +    ++  SP   +SP
Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP 683

Query: 232 GHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSP-------PRRSQPPGKK 284
              ++ S     ++  +  +   + +    ++  KS +   SP       P +++ P K+
Sbjct: 684 VKAEAKSP-EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKE 742

Query: 285 AAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERL 344
            A     AK     +  + +  ++K  + +T A E E +     F +K+  K  +K E +
Sbjct: 743 EAKSPEKAK-----SPEKAKTLDVKSPEAKTPAKE-EARSPADKFPEKA--KSPVK-EEV 793

Query: 345 EQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQ 404
           +   KA+   + D       K   +   +++ V+  +KE +KP  + +  ++  +   E+
Sbjct: 794 KSPEKAKSPLKED------AKAPEKEIPKKEEVKSPVKEEEKP--QEVKVKEPPKKAEEE 845

Query: 405 EREGDPMANFIKKNKAKENKNKKVRPRYSGPAP 437
           +    P      K + K++  K+  P+   P P
Sbjct: 846 KAPATP------KTEEKKDSKKEEAPKKEAPKP 872


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 68/381 (17%), Positives = 145/381 (38%), Gaps = 20/381 (5%)

Query: 67  EKEEEEDDGDLPVVAEFVDERPEEVKQMEAFR--SSAKWKLLGGHNEDLPSNRHFRHDTP 124
           E +EEE+        E   ER EE +Q +  R     + K      E     R  +    
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329

Query: 125 DSSPRRVRHGTPDPSPRKD----RHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180
               RR +    +   R++    R    +   ++ R +  +    +  R +      +++
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389

Query: 181 RHDSS--DTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDS 238
           R +         RR +    +    R  Q       ++  + +    +H+Q    Q    
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449

Query: 239 DLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVL 298
           +    R+  +           RR+Q+ K    +    R  +   ++        +  L  
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509

Query: 299 TDIQREQQELKEQDQET-----MAFEAEFQYAETVFRD---KSGRKRNLKLERLEQRRKA 350
              +R +Q LK Q++E      +  E + +  +   R+   K   ++ L+ ER EQR K 
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569

Query: 351 EKDSERDELYAQWGKGLAQ--SRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREG 408
           E++  RD+L  +  +   Q   R+Q++ +E  +K  ++ + R   +E  ++ L+ +E E 
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLK--REEVERLEQEERREQRLKREEPEE 627

Query: 409 DPMANFIKKNKAKENKNKKVR 429
           +     +K  + +E + +++R
Sbjct: 628 ERRQQLLKSEEQEERRQQQLR 648



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 36/139 (25%), Positives = 68/139 (48%), Gaps = 16/139 (11%)

Query: 302  QREQQELKEQDQETMAFEAEFQYAET---------VFRDKSGRKRNLKLERLEQRRKAEK 352
            Q E+Q L+E+ ++    E E QY E          + R++  ++R  +LER + R + E 
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER-QYREEEEL 1176

Query: 353  DSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMA 412
              E ++L  +  +   Q R++Q   E+ + + QK   RY D++    +  + E E +   
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEEL-QRQKRKQRYRDEDQRSDLKWQWEPEKE--- 1232

Query: 413  NFIKKNK--AKENKNKKVR 429
            N ++ NK   K  +N++ R
Sbjct: 1233 NAVRDNKVYCKGRENEQFR 1251



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 71/380 (18%), Positives = 139/380 (36%), Gaps = 47/380 (12%)

Query: 65  KLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTP 124
           +L +E+EE+  +  +  E    R +++++ +  R   + +      + L   +  R +  
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR----REQQLRREQQLRREQQ 418

Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDS 184
               +++R    +    + +H+      R  R        L+           RR +   
Sbjct: 419 LRREQQLRR-EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477

Query: 185 SDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPR 244
            D    RR R    +    R  Q       ++  +      R +Q    Q+ +  L   +
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEE-----RREQRLKRQEEEERL---Q 529

Query: 245 NRPRHRSSDSDLSPPRRRQRTKSSDSD-LSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQR 303
            R R           RR Q  K  +   L   RR Q    +        +  L+  + +R
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ----RLKREQEERRDQLLKREEER 585

Query: 304 EQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQW 363
            QQ LK + +E +                  R +  ++ERLEQ  + E+  +R+E   + 
Sbjct: 586 RQQRLKREQEERL----------------EQRLKREEVERLEQEERREQRLKREEPEEER 629

Query: 364 GKGLAQS-----RQQQQNVEDAMKEMQKPLARYIDDEDLD-RMLREQEREGDPMANFIKK 417
            + L +S     R+QQQ   +  +  ++ L R  ++E L+ R+ RE E E        ++
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER-------RE 682

Query: 418 NKAKENKNKKVRPRYSGPAP 437
            +  E + ++ R R     P
Sbjct: 683 QELAEEEQEQARERIKSRIP 702



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 27/132 (20%), Positives = 63/132 (47%), Gaps = 4/132 (3%)

Query: 302  QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYA 361
            +RE++ L+E++++    E   Q  E +  ++   +R  +LER  ++ +  +  E   L  
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLRE 1096

Query: 362  QWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDD----EDLDRMLREQEREGDPMANFIKK 417
            +  K   Q R++Q   E+ +++ ++ L R   +    ++L+R  RE+E         +++
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156

Query: 418  NKAKENKNKKVR 429
               K  + +  R
Sbjct: 1157 EPEKRRRQELER 1168



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 64/406 (15%), Positives = 152/406 (37%), Gaps = 54/406 (13%)

Query: 65  KLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTP 124
           +L++E+EE    L    E  + R + +K+ +  R   + K      E++      R +  
Sbjct: 566 RLKREQEERRDQLLKREE--ERRQQRLKREQEERLEQRLK-----REEVE-----RLEQE 613

Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRA---RHDTPDPSPLRGARHDSDTSPPRRIR 181
           +   +R++   P+   R+    + +   RR    R +  +    R  R + +    +R++
Sbjct: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK 673

Query: 182 HDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLS 241
            +  +    +    +  + +  R          Q  +++D    +    P  Q+      
Sbjct: 674 REHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQ 733

Query: 242 PPRNRPRHRSSDSDLSPPRRRQRTKSSDSD----------------------LSPPRRSQ 279
               + R R S+       R  R +  +                          PP R Q
Sbjct: 734 EQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793

Query: 280 PPGKKAAHMYSGAKTGLVLTDIQREQQ--ELKEQDQETMAFEAEFQY-----AETVFRDK 332
              +  A      +   +  + ++EQ+  + +E+++E    E E Q      A+ +  ++
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853

Query: 333 SGRKRNLKLERLEQRRK---------AEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKE 383
            G + + +  R +++R+          E+   R  LYA+      Q R++QQ +++  +E
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ-EQLRKEQQLLQEEEEE 912

Query: 384 MQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKNKKVR 429
           +Q+        ++ +R  RE+E+        +++ + K  + ++ R
Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER 958



 Score = 37.0 bits (84), Expect = 0.040
 Identities = 27/128 (21%), Positives = 63/128 (49%), Gaps = 9/128 (7%)

Query: 302  QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYA 361
            +RE++  +EQ+++    E   Q  E + R++  ++R  + ER  ++ K  +  E   L  
Sbjct: 917  EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE 976

Query: 362  QWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAK 421
            +  K   Q R+++   E+ +++         ++E L R  RE+ R  +    + KK++ +
Sbjct: 977  EPEKRRRQEREKKYREEEELQQ---------EEEQLLREEREKRRRQEWERQYRKKDELQ 1027

Query: 422  ENKNKKVR 429
            + + + +R
Sbjct: 1028 QEEEQLLR 1035



 Score = 37.0 bits (84), Expect = 0.040
 Identities = 31/142 (21%), Positives = 64/142 (45%), Gaps = 21/142 (14%)

Query: 300  DIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKR---------NLKLERLEQRRKA 350
            ++Q+E+++L  ++QE    E E QY E     +  RK+         +LK +   ++  A
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234

Query: 351  EKDSE------RDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQ 404
             +D++       +E + Q      + RQ QQ+++  + E Q+       D + +R   +Q
Sbjct: 1235 VRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE------RDREQERRRWQQ 1288

Query: 405  EREGDPMANFIKKNKAKENKNK 426
                 P    +++ + KE K +
Sbjct: 1289 RDRHFPEEEQLEREEQKEAKRR 1310



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 27/106 (25%), Positives = 55/106 (51%), Gaps = 10/106 (9%)

Query: 302 QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYA 361
           +RE+Q+   Q++E    E E++  ETV R     K   KL+  E +R+ E   E ++L  
Sbjct: 230 RRERQDRVFQEEE----EKEWRKRETVLR-----KEEEKLQEEEPQRQRELQEEEEQLRK 280

Query: 362 QWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE 407
              + L + RQ+++  +  ++  Q+ L R  ++E  ++    +E++
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQ-LRRKQEEERREQQEERREQQ 325



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 25/127 (19%), Positives = 65/127 (51%), Gaps = 14/127 (11%)

Query: 303 REQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQ 362
           + Q+EL+E++++    E +    E   +++  +++ L+ E+  +R++ E+  E+ E    
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRER--QEEEQQQQRLRREQQLRRKQEEERREQQE---- 319

Query: 363 WGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKE 422
                 + R+QQ+  E   +  ++ L R  ++    ++ REQE E       +++ + +E
Sbjct: 320 ------ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ--LRREQEEE 371

Query: 423 NKNKKVR 429
            + +++R
Sbjct: 372 RREQQLR 378



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 34/141 (24%), Positives = 65/141 (46%), Gaps = 14/141 (9%)

Query: 302  QREQQELKEQ-------DQETMAFEAEFQYAETVFRDKSGR-KRNLKLERLEQR-RKAEK 352
            +RE+Q+L+ Q       ++E +  E E Q   +   D+  R +  L+ ER EQ+ R  ++
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817

Query: 353  DS----ERDEL-YAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE 407
            D     E ++L   +  + L Q R +Q   E+     +K      +    +   R QERE
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877

Query: 408  GDPMANFIKKNKAKENKNKKV 428
                   I++ + +E ++++V
Sbjct: 1878 RKLREEHIRRQQKEEQRHRQV 1898



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 33/178 (18%), Positives = 72/178 (40%), Gaps = 17/178 (9%)

Query: 219  DSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRS 278
            +  L   R +Q    Q+SD        + R    +  L P +R  + +  +  L    + 
Sbjct: 1776 EEQLRQEREEQQLRSQESDRKFRE-EEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834

Query: 279  QPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRN 338
            Q   ++    Y   +        +RE+QEL +++++               + +  R+R 
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ---------------KRRQERERK 1879

Query: 339  LKLERLEQRRKAE-KDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDE 395
            L+ E + +++K E +  +  E+ +Q GKG  +  +   +   ++     PL  YI ++
Sbjct: 1880 LREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSPLYEYIQEQ 1937



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 28/142 (19%), Positives = 67/142 (47%), Gaps = 14/142 (9%)

Query: 300  DIQREQQELKEQDQETMAF-EAEFQYA---------ETVFRDKSGRKRNLKLERLEQRRK 349
            ++Q+E+++L  +++ET    E E QY          E + R++  ++R  + ER  +  +
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114

Query: 350  AEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDD----EDLDRMLREQE 405
              +  E   L  +  K   Q  ++Q   E+ +++ ++ L R   +    ++L+R  RE+E
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEE 1174

Query: 406  REGDPMANFIKKNKAKENKNKK 427
                     +++ + K  + ++
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERE 1196



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 39/214 (18%), Positives = 90/214 (42%), Gaps = 28/214 (13%)

Query: 234 QDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAK 293
           QD   +    R  PR R  + +    RRRQ+ +  + +L+         ++        +
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQ-RRRQKRQEQERELAEGEEQSEKQERLEQRDRQRR 169

Query: 294 TGLVLTDIQREQQELKEQDQ--------------ETMAFEAEFQYAETVFRDKSGRKRNL 339
                 ++ R++QE +E+++              ET  F  E Q      R+    +R  
Sbjct: 170 D----EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRR---RELLELRRKG 222

Query: 340 KLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDR 399
           + E+ +QRR+ +    ++E   +W K     R++++ +++   + Q+ L    ++E L +
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE--EEEQLRK 280

Query: 400 M----LREQEREGDPMANFIKKNKAKENKNKKVR 429
           +    LR + +E +     +++ +    K ++ R
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314



 Score = 32.3 bits (72), Expect = 0.99
 Identities = 52/259 (20%), Positives = 97/259 (37%), Gaps = 36/259 (13%)

Query: 149  DPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQH 208
            + S  R R    D   L G + + D    RR R    D   P   + +  +    +R   
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERR-RWQQRDRHFPEEEQLEREEQKEAKRRDR 1312

Query: 209  NSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSS 268
             S  + Q   +      R +++      +  L   R             P RR++R +  
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE----------QPLRRQERDRKF 1362

Query: 269  DSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETV 328
              +     R Q  G+K        +        +RE++ LKE+ Q+    E E Q  +  
Sbjct: 1363 REE---ELRHQEQGRKFLEEEQRLRRQ------ERERKFLKEE-QQLRCQEREQQLRQD- 1411

Query: 329  FRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPL 388
             RD+  R+   +L R E+ RK  ++ +             Q R+Q++  +   +E Q   
Sbjct: 1412 -RDRKFREEEQQLSRQERDRKFREEEQ-------------QVRRQERERKFLEEEQQLRQ 1457

Query: 389  ARYIDDEDLDRMLREQERE 407
             R+    + +++L+E+E +
Sbjct: 1458 ERHRKFREEEQLLQEREEQ 1476



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 64/373 (17%), Positives = 133/373 (35%), Gaps = 40/373 (10%)

Query: 65  KLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTP 124
           +L K EE+++     +     ER E+  + E      + +L   H E+    +    +  
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER-REQELAEEEQ 690

Query: 125 DSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDS 184
           + +  R++   P     K +      +  R       P    G R   +    RR R   
Sbjct: 691 EQARERIKSRIP-----KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745

Query: 185 SDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPR-HKQSPGHQDSDSDLSPP 243
                  RA     +    R    + +   Q    S+    R   + P  +  +  L   
Sbjct: 746 LQWQEEERAHRQQQEEEQRR----DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801

Query: 244 RNRPRHRS--SDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDI 301
             + R +    + +    RRRQR +            Q   ++ A      + GL     
Sbjct: 802 ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861

Query: 302 QREQQELKEQDQETMAFEAEFQ------YAETVFRDKSGRKRNLKLERLEQRRKAEKDSE 355
           +R  QE +   +     E E +      YA+   +++  +++ L  E  E+ ++ E++  
Sbjct: 862 RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR 921

Query: 356 RDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFI 415
           R            Q +++Q   E+ +++ ++ L R   +E   R  +E+ER+        
Sbjct: 922 R-----------RQEQERQYREEEQLQQEEEQLLR---EEREKRRRQERERQ-------Y 960

Query: 416 KKNKAKENKNKKV 428
           +K+K  + K +++
Sbjct: 961 RKDKKLQQKEEQL 973



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 25/107 (23%), Positives = 50/107 (46%), Gaps = 4/107 (3%)

Query: 301  IQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELY 360
            ++R++QE K  + E      E Q      RD+  R+    L+  E+++   +  ERD  +
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ--ERDRKF 1645

Query: 361  AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQERE 407
             +    L +  ++QQ   D  ++ ++     +  E  ++ LR QER+
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFRE--EEQLLQEGEEQQLRRQERD 1690



 Score = 30.4 bits (67), Expect = 3.8
 Identities = 51/247 (20%), Positives = 92/247 (37%), Gaps = 35/247 (14%)

Query: 178  RRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSD 237
            R+ R +        R R    +    R+ +H    +     +  L   R +Q    Q+ D
Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE-----EEQLLQEREEQQLHRQERD 1484

Query: 238  SDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLV 297
                    + R +  D       R Q  +S +     P R     ++  H     +  L 
Sbjct: 1485 RKFLEEEQQLRRQERDRKF----REQELRSQE-----PERKFLEEEQQLHRQQRQRKFLQ 1535

Query: 298  LTDIQREQQ--ELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSE 355
                 R Q+  + + QD++    E E    E   +  S ++R+ K  RLE+++   ++ E
Sbjct: 1536 EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF-RLEEQKVRRQEQE 1594

Query: 356  R----DELYAQWGKGLAQSRQQQ-----------QNVEDAMKEMQKPLARYIDDEDLDRM 400
            R    DE   +  +G  Q RQ++           Q  E+     Q+   +++++E     
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP---Q 1651

Query: 401  LREQERE 407
            LR QERE
Sbjct: 1652 LRRQERE 1658



 Score = 30.0 bits (66), Expect = 4.9
 Identities = 25/133 (18%), Positives = 63/133 (47%), Gaps = 13/133 (9%)

Query: 302  QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELY- 360
            Q  +++ +E+++         Q  E + R++  ++R  + ER + R+K E   E ++L  
Sbjct: 984  QEREKKYREEEELQ-------QEEEQLLREEREKRRRQEWER-QYRKKDELQQEEEQLLR 1035

Query: 361  AQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDD----EDLDRMLREQEREGDPMANFIK 416
             +  K   Q R++Q   E+ +++ ++ L     +    ++L+R  R++E         ++
Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095

Query: 417  KNKAKENKNKKVR 429
            +   K  + ++ R
Sbjct: 1096 EEPEKRRRQERER 1108



 Score = 29.6 bits (65), Expect = 6.4
 Identities = 26/129 (20%), Positives = 61/129 (47%), Gaps = 8/129 (6%)

Query: 301  IQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSE---RD 357
            ++R+++  K  ++E +  E E Q      RD+  R+     +  E+++   ++S+   R+
Sbjct: 1740 LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE 1799

Query: 358  ELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKK 417
            E   +  +   Q R QQ++ +   +E Q  L     +E   R+ +E++R+      F  +
Sbjct: 1800 EEQLRQEREEQQLRPQQRDGKYRWEEEQLQL-----EEQEQRLRQERDRQYRAEEQFATQ 1854

Query: 418  NKAKENKNK 426
             K++  + +
Sbjct: 1855 EKSRREEQE 1863


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 60/278 (21%), Positives = 112/278 (40%), Gaps = 32/278 (11%)

Query: 160 PDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATD 219
           P+ +P   A+   +    +R+R   S  S    A       S  R+   + S    K+  
Sbjct: 264 PEMTPQAAAKELEEVM--KRVREAQSFISA---AIEPESGKSNERKGGRSRSHTRSKSRS 318

Query: 220 SDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQ 279
           S  S  R K+S     S S      NR R R  D   S    ++R+KS +   S  R   
Sbjct: 319 SSKSHSRRKRSQSKHRSRS-----HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 373

Query: 280 PPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNL 339
              +K        K  +   D ++E++  KE+++E        +  +   RDK   K   
Sbjct: 374 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEK-------ERGKNKDRDKEREKDRE 426

Query: 340 KLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDR 399
           K +  ++ R+ EK+ E+D              ++++  +D  KE +K  ++ ID++   R
Sbjct: 427 KDKEKDREREREKEHEKDR------------DKEKEKEQDKEKEREKDRSKEIDEK---R 471

Query: 400 MLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAP 437
              ++ R      N  +++++   + ++ R R S  +P
Sbjct: 472 KKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 509



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 56/285 (19%), Positives = 95/285 (33%), Gaps = 48/285 (16%)

Query: 116 NRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTS 175
           +R  R     S  R  R  T +    K+R    D    R R    +    RG   D D  
Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420

Query: 176 PPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQD 235
             +    D        R +    D    +  + +   + +K    ++   R K       
Sbjct: 421 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR-- 478

Query: 236 SDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTG 295
                +PPR+    R S S  S  RRR+R++SS      PR S+   +K++   S     
Sbjct: 479 -----TPPRSYNASRRSRSS-SRERRRRRSRSSSRS---PRTSKTIKRKSSRSPSPRS-- 527

Query: 296 LVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKD-S 354
                                             R+K  +KR  + + + +RR+ E+  S
Sbjct: 528 ----------------------------------RNKKDKKREKERDHISERRERERSTS 553

Query: 355 ERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDR 399
            R     + GK   +        ++  KE    +++ +DD+D  R
Sbjct: 554 MRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 598


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 60/278 (21%), Positives = 112/278 (40%), Gaps = 32/278 (11%)

Query: 160 PDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATD 219
           P+ +P   A+   +    +R+R   S  S    A       S  R+   + S    K+  
Sbjct: 148 PEMTPQAAAKELEEVM--KRVREAQSFISA---AIEPESGKSNERKGGRSRSHTRSKSRS 202

Query: 220 SDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQ 279
           S  S  R K+S     S S      NR R R  D   S    ++R+KS +   S  R   
Sbjct: 203 SSKSHSRRKRSQSKHRSRS-----HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 257

Query: 280 PPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNL 339
              +K        K  +   D ++E++  KE+++E        +  +   RDK   K   
Sbjct: 258 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEK-------ERGKNKDRDKEREKDRE 310

Query: 340 KLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDR 399
           K +  ++ R+ EK+ E+D              ++++  +D  KE +K  ++ ID++   R
Sbjct: 311 KDKEKDREREREKEHEKDR------------DKEKEKEQDKEKEREKDRSKEIDEK---R 355

Query: 400 MLREQEREGDPMANFIKKNKAKENKNKKVRPRYSGPAP 437
              ++ R      N  +++++   + ++ R R S  +P
Sbjct: 356 KKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 393



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 56/285 (19%), Positives = 95/285 (33%), Gaps = 48/285 (16%)

Query: 116 NRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTS 175
           +R  R     S  R  R  T +    K+R    D    R R    +    RG   D D  
Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304

Query: 176 PPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQD 235
             +    D        R +    D    +  + +   + +K    ++   R K       
Sbjct: 305 REKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR-- 362

Query: 236 SDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTG 295
                +PPR+    R S S  S  RRR+R++SS      PR S+   +K++   S     
Sbjct: 363 -----TPPRSYNASRRSRSS-SRERRRRRSRSSSRS---PRTSKTIKRKSSRSPSPRS-- 411

Query: 296 LVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKD-S 354
                                             R+K  +KR  + + + +RR+ E+  S
Sbjct: 412 ----------------------------------RNKKDKKREKERDHISERRERERSTS 437

Query: 355 ERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDR 399
            R     + GK   +        ++  KE    +++ +DD+D  R
Sbjct: 438 MRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPR 482


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 54/275 (19%), Positives = 93/275 (33%), Gaps = 35/275 (12%)

Query: 122 DTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPD----PSPLRGARHDSDTSPP 177
           D   S   R R  TPD    +DR     PS  R RH + D     S  R           
Sbjct: 12  DASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERE 71

Query: 178 RRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSD 237
           RR +    D    R  +    D    RR +             D  S + + S   ++ +
Sbjct: 72  RRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDE 131

Query: 238 SDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLV 297
                P+ +P   S +  L+  +  +  ++    LS   R     K+             
Sbjct: 132 HGDKKPKAQP--LSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQ---------- 179

Query: 298 LTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERD 357
             +++  Q+ L+E+ ++   F+        +  D   R+R  + ER+E+     +D E  
Sbjct: 180 --EVEERQRMLEEERKKRKQFQ---DLGRKMLEDPQERERRERRERMERETNGNEDEE-- 232

Query: 358 ELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYI 392
                        RQ+ +  +D  KE+     RY+
Sbjct: 233 ------------GRQKIREEKDKSKELHAIKERYL 255



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 47/213 (22%), Positives = 92/213 (43%), Gaps = 15/213 (7%)

Query: 199 DPSPPRRPQHNS-SGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLS 257
           D SP +  +  S + D ++  D D  S   K    H+  D      R+R R RS  ++  
Sbjct: 12  DASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERE 71

Query: 258 PPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMA 317
              RR + +  D +    ++ +   K         K   +     ++ +  K++D +   
Sbjct: 72  ---RRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSK--- 125

Query: 318 FEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQS-RQQQQN 376
                +  E    DK  + + L LE L  ++KAE+++E    +    +  A++ +++QQ 
Sbjct: 126 -----KDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQE 180

Query: 377 VEDAMKEMQKPLARYIDDEDLDRMLRE--QERE 407
           VE+  + +++   +    +DL R + E  QERE
Sbjct: 181 VEERQRMLEEERKKRKQFQDLGRKMLEDPQERE 213


>gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens]
          Length = 299

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/169 (28%), Positives = 59/169 (34%), Gaps = 26/169 (15%)

Query: 128 PRRVRHGTPDPSPRKD----------RHDTPDP----SPRRARHDTPDPSPLRGAR-HDS 172
           P RV+     P PR+D            +TP P    +PR    DTP P      R  D 
Sbjct: 38  PERVKQCC-QPCPRRDLLASWPCRLFSSETPRPRDCETPRPRDCDTPRPRDCETPRPRDC 96

Query: 173 DTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPG 232
           DT  PR       D   PR    D+P P     P+     DC      D  +PR +    
Sbjct: 97  DTPRPR-------DCETPRPRDCDTPRPRDCETPRPR---DCDTPRPRDCETPRPRDCET 146

Query: 233 HQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPP 281
            +  D D   PR+    R  D D   PR     +  D D   PR    P
Sbjct: 147 PRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTP 195



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 45/148 (30%), Positives = 56/148 (37%), Gaps = 18/148 (12%)

Query: 117 RHFRHDTPD----SSPRRVRHGTPDP----SPRKDRHDTPDP----SPRRARHDTPDPSP 164
           R F  +TP      +PR     TP P    +PR    DTP P    +PR    DTP P  
Sbjct: 60  RLFSSETPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRD 119

Query: 165 LRGAR-HDSDTSPPRRIRHDSS-DTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDL 222
               R  D DT  PR        D   PR    D+P P     P+     DC      D 
Sbjct: 120 CETPRPRDCDTPRPRDCETPRPRDCETPRPRDCDTPRPRDCDTPRPR---DCDTPRPRDC 176

Query: 223 SSPRHKQSPGHQDSDSDLSPPRNRPRHR 250
            +PR +     +  D D   PR+  +HR
Sbjct: 177 DTPRPRDCDTPRPRDCDTPRPRDL-KHR 203


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 57/192 (29%), Positives = 79/192 (41%), Gaps = 12/192 (6%)

Query: 115  SNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDT 174
            + R  R  TP ++ RR R  TP  + R+ R  TP  + RR+R  T   SP+   R  S T
Sbjct: 1931 TRRRSRSRTP-TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRT---SPITRRRSRSRT 1986

Query: 175  SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQ 234
            SP  R R  S  +   RR       P   RR +  +    ++ + S       K+S    
Sbjct: 1987 SPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRS 2046

Query: 235  DSDSDLSPPRNRPRHRSSDSDL--SPPRRRQRTKS-SDSDLSPPRRSQPPGKKAAHMYSG 291
                        PR       L  SPP  R+R+ S S SD S  R + PP   A   +SG
Sbjct: 2047 PLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRS--RSATPP---ATRNHSG 2101

Query: 292  AKTGLVLTDIQR 303
            ++T  V  +  R
Sbjct: 2102 SRTPPVALNSSR 2113



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 47/162 (29%), Positives = 68/162 (41%), Gaps = 25/162 (15%)

Query: 124  PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPD-PSPLRGARHDSDTSPPRRIRH 182
            P + PRR R G    S  K R  +P+ S   +   +P+ P   R AR  S +SP  + + 
Sbjct: 1629 PRALPRRSRSG----SSSKGRGPSPEGSS--STESSPEHPPKSRTARRGSRSSPEPKTK- 1681

Query: 183  DSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSP 242
              S T P RR+   SP+ +   R    S            + PRH++SP        +S 
Sbjct: 1682 --SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSP-------SVSS 1732

Query: 243  PRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKK 284
            P    + RSS        RR+R+ SS    +  RR + P  K
Sbjct: 1733 PEPAEKSRSS--------RRRRSASSPRTKTTSRRGRSPSPK 1766



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 85/387 (21%), Positives = 131/387 (33%), Gaps = 50/387 (12%)

Query: 28  SESGRKRRKKR-PKPGGAGGKGMRIVDDDVSWTAISTTKLEKEEEEDDGDLPVVAEFVDE 86
           SES  K+RK R P P     K  R   D     + STT   K            A   D 
Sbjct: 220 SESESKKRKHRSPTP-----KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274

Query: 87  RPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFRHDTPDSSPRRV---RHGTPDPSPR-- 141
                +   A   +     L G +    S R    D P S P      R  +P+ + +  
Sbjct: 275 SRSRSRSAAAKTHTTA---LAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQP 331

Query: 142 --------KDRHDT----PDPSPRRARH--DTPDPSPLRGARHDSDTSP----------- 176
                   KD+ +     P PSP R+    + P P+PL   RH     P           
Sbjct: 332 SSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPV 391

Query: 177 -PRRIRHDSSDTSPPR---RARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPG 232
            P      + D SPP+   +    S   S P  PQ        +   S   SP+   +PG
Sbjct: 392 NPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK---VSRHASSSPESPKPAPAPG 448

Query: 233 HQDSDSDLSPPRNRPR---HRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMY 289
                S     +NR      R      +P RR  R++S  +      RS+ P K+  H  
Sbjct: 449 SHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKR-GHSR 507

Query: 290 SGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRK 349
           S +         QR  +    Q +          ++ +    + GR R+ +  R   R  
Sbjct: 508 SRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSP 567

Query: 350 AEKDSERDELYAQWGKGLAQSRQQQQN 376
           A +   R    A+ G+  +++  ++++
Sbjct: 568 ATRGRSRSRTPARRGRSRSRTPARRRS 594



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 68/297 (22%), Positives = 104/297 (35%), Gaps = 25/297 (8%)

Query: 1    MAAAPPLSKAEYLKRYLSGADAGVDRGSESGRKRRKKRPKPGGAGGKGMRIVDDDVSWTA 60
            +++  P  K+   +R  S   A   R   + R+ R   PKP G      R          
Sbjct: 1730 VSSPEPAEKSRSSRRRRS---ASSPRTKTTSRRGRSPSPKPRGLQRSRSR---------- 1776

Query: 61   ISTTKLEKEEEEDDGDLPVVAEFVDERPEEVKQMEAFRSSAKWKLLGGHNEDLPSNRHFR 120
               ++ EK       D    ++    R    +Q    RS    +  GG      S     
Sbjct: 1777 ---SRREKTRTTRRRDRSGSSQSTSRR----RQRSRSRSRVTRRRRGGSGYHSRSPARQE 1829

Query: 121  HDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRI 180
                 S  RR R  TP P+ RK       P+P +       P+  R +R  +     RR 
Sbjct: 1830 SSRTSSRRRRGRSRTP-PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888

Query: 181  RHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDL 240
            R   S TSP  R R  S      RR +  +S   ++ + S       ++S     +    
Sbjct: 1889 R---SRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRR 1945

Query: 241  SPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLV 297
            S  R  P  R      +PP  R+R++S  S ++  RRS+          S ++T  V
Sbjct: 1946 SRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPIT-RRRSRSRTSPVTRRRSRSRTSPV 2001



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 42/139 (30%), Positives = 53/139 (38%), Gaps = 29/139 (20%)

Query: 175 SPPRRIRHDSSDT-----SPPRRARHDSPDP-----SPPRRPQHNSSGDCQKATDSDLSS 224
           +PPRR R  SS       +PPRR+R  S  P       P R  H+SS    K      + 
Sbjct: 792 TPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSG--TP 849

Query: 225 PRHKQSPGHQDSDSDLSPPR-------------NRPRHRSSDSDLSPPRRRQRTKSSDSD 271
           PR       Q ++  ++P R             +R   R S S  SPPR     KSS   
Sbjct: 850 PRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPR----VKSSTPP 905

Query: 272 LSPPRRSQPPGKKAAHMYS 290
              P RS  P  K   + S
Sbjct: 906 RQSPSRSSSPQPKVKAIIS 924



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 39/167 (23%), Positives = 59/167 (35%), Gaps = 3/167 (1%)

Query: 124  PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHD 183
            P  + R  R   P P+ RK R  +   S   +   +   S    +   S +S        
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2645

Query: 184  SSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPP 243
            SS  SP +      P P+ P++P         ++    + S R  +S  +   +     P
Sbjct: 2646 SSSPSPAKPGPQALPKPASPKKPPPGERR--SRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703

Query: 244  RNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYS 290
            +  PR + S S     RR QR   S S     RR  P  +   H  S
Sbjct: 2704 QPSPRDQQSSSSERGSRRGQR-GDSRSPSHKRRRETPSPRPMRHRSS 2749



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 51/219 (23%), Positives = 87/219 (39%), Gaps = 18/219 (8%)

Query: 112  DLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHD 171
            +L S    RH    SSP RV+  TP   PR+    +  P P+     +P     R   H 
Sbjct: 880  ELKSRTPSRHSCSGSSPPRVKSSTP---PRQSPSRSSSPQPKVKAIISP-----RQRSHS 931

Query: 172  SDTSP-PRRIRHDSSDTSPPRRARHDSPDPSPPRR--PQHNSSGDCQKATDSDLSSPRHK 228
              +SP P R+    +  + PRR+R  SP  +   R  P+++ SG     T     +P  +
Sbjct: 932  GSSSPSPSRV----TSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQ 987

Query: 229  QSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHM 288
                H  S S     + +     S S    P  ++++K S     P   S   G K++  
Sbjct: 988  ---SHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTP 1044

Query: 289  YSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAET 327
               +  G+    ++ + Q   +   +T + E    ++E+
Sbjct: 1045 PGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSES 1083



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 43/188 (22%), Positives = 61/188 (32%), Gaps = 30/188 (15%)

Query: 128 PRRVRHGTPDP------SPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRR-- 179
           PRR R  +  P      +P +  H +  P P+      P    +   + +  +  P+R  
Sbjct: 812 PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRS 871

Query: 180 ---------------IRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSS 224
                           RH  S +SPPR         +PPR+    SS    K     + S
Sbjct: 872 CFESSPDPELKSRTPSRHSCSGSSPPR-----VKSSTPPRQSPSRSSSPQPKV--KAIIS 924

Query: 225 PRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKK 284
           PR +   G           R  PR   S S  S    R   + S S  S P     P   
Sbjct: 925 PRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETP 984

Query: 285 AAHMYSGA 292
               +SG+
Sbjct: 985 PRQSHSGS 992



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 48/185 (25%), Positives = 64/185 (34%), Gaps = 10/185 (5%)

Query: 111  EDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLR-GAR 169
            +D+P          DSSP       P   P+  R  +  PS     +    P   R G+ 
Sbjct: 1467 KDIPRTPSRGRSECDSSPE------PKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSE 1520

Query: 170  HDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQ 229
               D     R        S   +     P  SP  R + +SS D +  T + L       
Sbjct: 1521 SSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSG 1580

Query: 230  SPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMY 289
            S    DS S LSP   R R  SS      PR   R +S  SD SP  ++  P        
Sbjct: 1581 SSPEVDSKSRLSP--RRSRSGSSPEVKDKPRAAPRAQSG-SDSSPEPKAPAPRALPRRSR 1637

Query: 290  SGAKT 294
            SG+ +
Sbjct: 1638 SGSSS 1642



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 43/196 (21%), Positives = 72/196 (36%), Gaps = 21/196 (10%)

Query: 140  PRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTS----------PPRRIRHDSSDTSP 189
            P K+R  +   S   +   +   S    +   S +S          P   ++   S T  
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA 2585

Query: 190  PRRARHDS--PDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRP 247
            P+ A  +   P+P+P +R + +SS     ++ S  SS     S     S S  S   +  
Sbjct: 2586 PKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-- 2643

Query: 248  RHRSSDSDLSP--PRRRQRTKSSDSDLSPP--RRSQPPGKKAAHMYSGAKTGLVLTDIQR 303
               SS S  SP  P  +   K +     PP  RRS+ P K    +           + +R
Sbjct: 2644 ---SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRR 2700

Query: 304  EQQELKEQDQETMAFE 319
               +   +DQ++ + E
Sbjct: 2701 PSPQPSPRDQQSSSSE 2716



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 31/131 (23%), Positives = 50/131 (38%), Gaps = 3/131 (2%)

Query: 137 DPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHD 196
           DP  R      P P P +      + S  R           ++ R   S++S PRR R  
Sbjct: 152 DPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKK 211

Query: 197 SPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDL 256
           S   S  ++ +  S    +K       S R  +    + S S    P++R  HRS+ +D 
Sbjct: 212 S---SKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADS 268

Query: 257 SPPRRRQRTKS 267
           +      R++S
Sbjct: 269 ASSSDTSRSRS 279



 Score = 37.4 bits (85), Expect = 0.031
 Identities = 84/391 (21%), Positives = 137/391 (35%), Gaps = 48/391 (12%)

Query: 107 GGHNE--DLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDRHDTPDPSPR-RARHDTPDPS 163
           G H E    P++++  H       +R +  +  PS R  R  +P  + R R+R  TP   
Sbjct: 448 GSHREISSSPTSKNRSH----GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTK- 502

Query: 164 PLRGARHDSDTSPPRRIRHDSS----DTSPPRRARHDSPDPSPPRRPQHNSSGDCQK--A 217
             RG  H    SP  R    +       SP RR R  S     P+RP  + S + Q+   
Sbjct: 503 --RG--HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRS-----PQRPGWSRSRNTQRRGR 553

Query: 218 TDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQR----TKSSDSDLS 273
           + S      H +SP  +      +P R R R RS     +P RRR R    T+      +
Sbjct: 554 SRSARRGRSHSRSPATRGRSRSRTPAR-RGRSRSR----TPARRRSRSRTPTRRRSRSRT 608

Query: 274 PPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFR--- 330
           P RR +   +  A   S  ++ +      R       + +           + T  R   
Sbjct: 609 PARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR 668

Query: 331 -------DKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKE 383
                   +SGR R+    R  + R       R    +   +G + SR  Q+        
Sbjct: 669 SRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728

Query: 384 MQKPLARYIDDEDLDRMLRE--QEREGDPMANFIKKNKAKENKNKKVRPRYSGPAPPPNR 441
            +K  +R            E  + R     +  +   ++K      +R   SG +P P +
Sbjct: 729 ERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQ 788

Query: 442 FNIWPGYRWDGVDRSNGFEQKRFARLASKKA 472
            +  P  R     RS   + K  +R   +++
Sbjct: 789 KSQTPPRR----SRSGSSQPKAKSRTPPRRS 815



 Score = 36.6 bits (83), Expect = 0.053
 Identities = 69/307 (22%), Positives = 107/307 (34%), Gaps = 70/307 (22%)

Query: 127  SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTP---DPSPLRGARHDSDTSP------- 176
            +P+R R G+     +K    TP     R+         PS     R +SD+SP       
Sbjct: 1511 TPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTR 1570

Query: 177  -PRRIRH--------DSSDTSPPRRAR---------------------HDSPDPSP---- 202
             P R R         DS     PRR+R                       SP+P      
Sbjct: 1571 TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR 1630

Query: 203  --PRRPQHNSS----GDCQKATDSDLSSPRHKQSP-----GHQDSDSDLSPPRNRPRHRS 251
              PRR +  SS    G   + + S  SSP H         G + S    +  R  PR RS
Sbjct: 1631 ALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRS 1690

Query: 252  SDSDLSPPRRRQRTKSSDSDLSPP--RRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELK 309
            S S     R+ + ++ S S  S P  R   PP  + +   S  +            ++ +
Sbjct: 1691 SRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPA----------EKSR 1740

Query: 310  EQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQ 369
               +   A     +      R  S + R L+  R   RR+  + + R +   + G   + 
Sbjct: 1741 SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD---RSGSSQST 1797

Query: 370  SRQQQQN 376
            SR++Q++
Sbjct: 1798 SRRRQRS 1804



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 41/156 (26%), Positives = 60/156 (38%), Gaps = 6/156 (3%)

Query: 124  PDSSPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDT---PDPSPLRGARHDSDTSPPRRI 180
            P S+  RV   T  P   + R  TP  +P ++R  +   P PS   G        PP + 
Sbjct: 2386 PLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445

Query: 181  RHDSSDTSP-PRRARHDSPDPSPPRRPQHNSSGDCQKATDS--DLSSPRHKQSPGHQDSD 237
            +  S   S    ++R      +P    Q  SSG     T S  D +      +PG   SD
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505

Query: 238  SDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLS 273
                P     +  S+ + L P + R+ + SS S  S
Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 5/58 (8%)

Query: 120  RHDTPDSSPRRVRHGTPDPSPRK-DRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSP 176
            R  +P  SPR  +  + +   R+  R D+  PS +R R +TP P P+   RH S  SP
Sbjct: 2699 RRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR-RRETPSPRPM---RHRSSRSP 2752



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 32/127 (25%), Positives = 45/127 (35%), Gaps = 24/127 (18%)

Query: 183 DSSDTSPPRRARH-DSPDPSPPR-----RPQHNSSGDCQKATD----------SDLSSPR 226
           D S   P RRAR    P P PP+     R   +S     K             S+ SSPR
Sbjct: 147 DGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206

Query: 227 HKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQP-PGKKA 285
            ++    +           + +HRS       P  + + KS D      R + P P  + 
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRS-------PTPKSKRKSKDKKRKRSRSTTPAPKSRR 259

Query: 286 AHMYSGA 292
           AH  + A
Sbjct: 260 AHRSTSA 266


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 62/253 (24%), Positives = 104/253 (41%), Gaps = 46/253 (18%)

Query: 136 PDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARH 195
           PD    K RH       RR R  TP  S     RH    S  RR  H  S      R+R 
Sbjct: 239 PDKKEEKRRHSRSRSRSRRRR--TPSSS-----RHRRSRSRSRRRSHSKS------RSRR 285

Query: 196 DSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSD 255
            S   SP RR  H+     ++   S  +S    +    ++     +PP++    R S S 
Sbjct: 286 RSK--SPRRRRSHSR----ERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRS- 338

Query: 256 LSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQET 315
            S  RRR+R++S       P++ + P +K +   S  +          ++++ K++D+E 
Sbjct: 339 ASRERRRRRSRSGTRS---PKKPRSPKRKLSRSPSPRR---------HKKEKKKDKDKER 386

Query: 316 MAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQ 375
              E E        R  S +K++   E+ ++ RK+E D +  ++   +        +Q  
Sbjct: 387 SRDERE--------RSTSKKKKSKDKEK-DRERKSESDKDVKQVTRDY-----DEEEQGY 432

Query: 376 NVEDAMKEMQKPL 388
           + E   KE +KP+
Sbjct: 433 DSEKEKKEEKKPI 445



 Score = 32.3 bits (72), Expect = 0.99
 Identities = 28/137 (20%), Positives = 51/137 (37%), Gaps = 12/137 (8%)

Query: 295 GLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDS 354
           GLV   ++ +    + ++      EA+   +  +  DK   KR     R   RR+    S
Sbjct: 204 GLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSS 263

Query: 355 ERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANF 414
            R        +  ++SR++  +   + +  + P  R     +  R  R   +  D     
Sbjct: 264 SRHR------RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRD----- 312

Query: 415 IKKNKAKENKNKKVRPR 431
            KK + KE K  K  P+
Sbjct: 313 -KKKEDKEKKRSKTPPK 328



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 32/150 (21%), Positives = 55/150 (36%), Gaps = 9/150 (6%)

Query: 117 RHFRHDTPDSSPRRVRHGTPDPS-PRKDRHD-TPDPSPRRARHDTPDPSPLRGARHDSDT 174
           R  R  + +   RR R GT  P  PR  +   +  PSPRR + +         +R + + 
Sbjct: 334 RRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERER 393

Query: 175 SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSG-DCQKATDS-----DLSSPRHK 228
           S  ++ +    +    R++  D       R       G D +K         +  SP+ K
Sbjct: 394 STSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTK 453

Query: 229 QSPGHQDSDSDLSPPR-NRPRHRSSDSDLS 257
           +    + +   L   + N   H   D D+S
Sbjct: 454 ECSVEKGTGDSLRESKVNGDDHHEEDMDMS 483


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 52/180 (28%), Positives = 68/180 (37%), Gaps = 10/180 (5%)

Query: 123 TPDSSPRRVRHGTPDPSPRKDR---HDTPDPS----PRRARHDTPDPSPLRGARHDSDTS 175
           +P  S +  +   P  S R  R   +    PS    P+ +  D+      R  R     S
Sbjct: 432 SPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYS 491

Query: 176 PPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQD 235
           P R+ R DS      RR       P P  RP  +SSG     +    SS     S  +  
Sbjct: 492 PMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSR 551

Query: 236 SDS-DLSPPRNRPRHRSSDSDLSP-PRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAK 293
           S S   S  R+R R  SS S  SP P  R R++S     S   RSQ     +A  YS  +
Sbjct: 552 SRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRS-RSRSQSRSYSSADSYSSTR 610



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 9/151 (5%)

Query: 135 TPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRAR 194
           TP PS R  +        +R R  +  PSP++  +  S     RR        S  ++ R
Sbjct: 101 TPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRR-------RSFSKKRR 153

Query: 195 HDSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDS 254
           H S  P   RR +       +           H+     Q S+S  S   +R R RS + 
Sbjct: 154 HSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEE 213

Query: 255 DLSPPRRRQR--TKSSDSDLSPPRRSQPPGK 283
                RR  R  +K+   D    + S+PP +
Sbjct: 214 GQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQ 244



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 36/133 (27%), Positives = 53/133 (39%), Gaps = 14/133 (10%)

Query: 168 ARHDSDTSPP--RRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSS------GDCQKATD 219
           A HD D +PP   R +     ++  +R R  S  PSP ++ +  SS          K   
Sbjct: 94  ASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRR 153

Query: 220 SDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQ 279
              SSP+ K+    +      S PR   RHR        P R Q ++S  S      R +
Sbjct: 154 HSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRC----PSRSQSSESRPSSCESRHRGR 209

Query: 280 PP--GKKAAHMYS 290
            P  G+K+   +S
Sbjct: 210 SPEEGQKSRRRHS 222



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 48/204 (23%), Positives = 76/204 (37%), Gaps = 24/204 (11%)

Query: 104 KLLGGHNEDLPSNRHFRHDTPDSSPRRVRHGTPDPSPRKDR-HDTPDPSPRRARHDTPDP 162
           +L  G+  D  S   F   +P +    + + +P    R+ R   +P       +  +  P
Sbjct: 321 ELNSGNTSD--SGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVP 378

Query: 163 SPLRGARHDSDTSPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGDCQKATDSDL 222
           S  R        S P +    SS  +  R + H S  P+P   P++  S        S  
Sbjct: 379 STAR--------SSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYS 430

Query: 223 SSPRH-----KQSPGHQDSDSDLSPPRNR--------PRHRSSDSDLSPPRRRQRTKSSD 269
            SP +     K+SP  + S S  SP  +R        P++   DS      R +R + S 
Sbjct: 431 RSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSY 490

Query: 270 SDLSPPRRSQPPGKKAAHMYSGAK 293
           S +   RR  P   +A  + S  K
Sbjct: 491 SPMRKRRRDSPSHLEARRITSARK 514


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 32/127 (25%), Positives = 66/127 (51%), Gaps = 8/127 (6%)

Query: 283 KKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSG--RKRNLK 340
           ++A  +    +T  +  ++ R+++EL+EQ+++    E +    E   R++ G  R++  K
Sbjct: 218 ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEK 277

Query: 341 LERLEQR-RKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDR 399
           + R E+R R+ EK+    E   +  K L +  +Q Q  E+ M E ++ +      E  ++
Sbjct: 278 MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR-----EQEEK 332

Query: 400 MLREQER 406
           M R++ER
Sbjct: 333 MWRQEER 339



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 26/130 (20%), Positives = 64/130 (49%), Gaps = 9/130 (6%)

Query: 302 QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQ--RRKAEKDSERDEL 359
           ++ ++E K Q+QE   ++ E    E +  ++  R+R  K+   E+  R + EK  E++E 
Sbjct: 534 EKMREEKKTQEQEKKTWDQE----EKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589

Query: 360 YAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNK 419
             +  + + +  ++ Q  E+ M E ++ +    + E+ D+M  ++E   +      ++ +
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMW---EQEEEDKMQEQEEMMWEQEEKMQEQEE 646

Query: 420 AKENKNKKVR 429
               + +K+R
Sbjct: 647 KMWEQEEKMR 656



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 34/144 (23%), Positives = 69/144 (47%), Gaps = 17/144 (11%)

Query: 303 REQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDE---- 358
           R+++ L+EQ+ +    E + +  E   R++    R  + E  EQ++  E++ +  E    
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEK 318

Query: 359 LYAQWGKGLAQSR---QQQQNVEDAMKEMQKPLARYIDDE----DLDRMLREQE---REG 408
           ++ Q  K   Q     +Q++ + +  K+M++   +  D E    + D  LRE+E   RE 
Sbjct: 319 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378

Query: 409 DPMANFIKKNKAKE---NKNKKVR 429
           + M    +K + +E    + KK+R
Sbjct: 379 EKMWEQEEKMQEEERIREREKKMR 402



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 23/128 (17%), Positives = 63/128 (49%), Gaps = 3/128 (2%)

Query: 304 EQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQW 363
           EQ++++EQ+++    E + +  E ++  +    R  K+   E +   +++  RD+    W
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW 503

Query: 364 G--KGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAK 421
              + + +  ++ +  E+ M+E QK + +  +    ++  +EQE++       +++ +  
Sbjct: 504 DQEERMWEQDERLREKEERMRE-QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562

Query: 422 ENKNKKVR 429
             + KK+R
Sbjct: 563 REREKKMR 570



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 23/119 (19%), Positives = 57/119 (47%), Gaps = 2/119 (1%)

Query: 305 QQELKEQDQETMAFEAEFQYAETVFRDKSGR--KRNLKLERLEQRRKAEKDSERDELYAQ 362
           Q++++EQ+ +    E + +  E    D+  R  +++ +L   E+R + +K   + E   +
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537

Query: 363 WGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAK 421
             K   +  ++  + E+ M+E ++   R     + + M+REQE +       +++ + K
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 19/85 (22%), Positives = 45/85 (52%), Gaps = 3/85 (3%)

Query: 302 QREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYA 361
           Q  +QE K +DQE   +E + +  E   +++  R++    E+ E+ ++ E+  ER++   
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLRE---KEERMREQEKMWEQEEKMQEEERIREREKKMR 402

Query: 362 QWGKGLAQSRQQQQNVEDAMKEMQK 386
           +  + + +  ++ Q  E+ M E ++
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEE 427



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 28/137 (20%), Positives = 67/137 (48%), Gaps = 14/137 (10%)

Query: 300 DIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRK-RNLKLERLEQR--RKAEKDSER 356
           +  REQ+E  ++ +E M  + E ++ +    ++  +     K++  E++   + EK  ++
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465

Query: 357 DELYAQWGKGLAQSRQQQQNVEDAMKEMQKPL----ARYIDDEDL-----DRMLREQERE 407
           +E++ Q  K   Q + ++Q  ED M E ++ +     +  D E+      +R+  ++ER 
Sbjct: 466 EEMWGQEKKMWRQEKMREQ--EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM 523

Query: 408 GDPMANFIKKNKAKENK 424
            +    + ++ K +E K
Sbjct: 524 REQKKMWQQEEKMREEK 540


>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 38/143 (26%), Positives = 53/143 (37%), Gaps = 7/143 (4%)

Query: 136 PDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARH 195
           P P+ RKDR D       + +  T + S     R  +      R RH +S  S   R+R 
Sbjct: 26  PSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKT------RKRHSASSGSSSTRSRS 79

Query: 196 DSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNR-PRHRSSDS 254
            S   S       +SSG    +  S   S    +S     S    SP R R    R S S
Sbjct: 80  SSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRS 139

Query: 255 DLSPPRRRQRTKSSDSDLSPPRR 277
              PP+R ++ +   S    P +
Sbjct: 140 KSKPPKRDEKERKRRSPSPKPTK 162



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 42/175 (24%), Positives = 62/175 (35%), Gaps = 23/175 (13%)

Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD 186
           SP R RH     S  K +    D   R+ R  +P P+ +   R        R +  D   
Sbjct: 125 SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLT------RNVTKDHIM 178

Query: 187 TSPPRRARHDSPDPSPPRRPQHNSSG-DCQKATDSDLSSPRHKQSPGHQDSDSDLSP--- 242
                  +    D    R   H S G  C +  + D +    K   G Q    +++    
Sbjct: 179 EIFSTYGKIKMIDMPVERMHPHLSKGYACVEFENPDEAEKALKHMDGGQIDGQEITATVV 238

Query: 243 ----PRNRPRHRSSDSDL---------SPPRRRQRTKSSDSDLSPPRRSQPPGKK 284
               PR  PR  S    +         SPPR R+R++S        RRS+ PG++
Sbjct: 239 LAPWPRPTPRRFSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRSPGRR 293


>gi|169166499 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 38/143 (26%), Positives = 53/143 (37%), Gaps = 7/143 (4%)

Query: 136 PDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARH 195
           P P+ RKDR D       + +  T + S     R  +      R RH +S  S   R+R 
Sbjct: 26  PSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKT------RKRHSASSGSSSTRSRS 79

Query: 196 DSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNR-PRHRSSDS 254
            S   S       +SSG    +  S   S    +S     S    SP R R    R S S
Sbjct: 80  SSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRS 139

Query: 255 DLSPPRRRQRTKSSDSDLSPPRR 277
              PP+R ++ +   S    P +
Sbjct: 140 KSKPPKRDEKERKRRSPSPKPTK 162



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 42/175 (24%), Positives = 62/175 (35%), Gaps = 23/175 (13%)

Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD 186
           SP R RH     S  K +    D   R+ R  +P P+ +   R        R +  D   
Sbjct: 125 SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLT------RNVTKDHIM 178

Query: 187 TSPPRRARHDSPDPSPPRRPQHNSSG-DCQKATDSDLSSPRHKQSPGHQDSDSDLSP--- 242
                  +    D    R   H S G  C +  + D +    K   G Q    +++    
Sbjct: 179 EIFSTYGKIKMIDMPVERMHPHLSKGYACVEFENPDEAEKALKHMDGGQIDGQEITATVV 238

Query: 243 ----PRNRPRHRSSDSDL---------SPPRRRQRTKSSDSDLSPPRRSQPPGKK 284
               PR  PR  S    +         SPPR R+R++S        RRS+ PG++
Sbjct: 239 LAPWPRPTPRRFSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRSPGRR 293


>gi|113415498 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 38/143 (26%), Positives = 53/143 (37%), Gaps = 7/143 (4%)

Query: 136 PDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSDTSPPRRARH 195
           P P+ RKDR D       + +  T + S     R  +      R RH +S  S   R+R 
Sbjct: 26  PSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKT------RKRHSASSGSSSTRSRS 79

Query: 196 DSPDPSPPRRPQHNSSGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNR-PRHRSSDS 254
            S   S       +SSG    +  S   S    +S     S    SP R R    R S S
Sbjct: 80  SSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRS 139

Query: 255 DLSPPRRRQRTKSSDSDLSPPRR 277
              PP+R ++ +   S    P +
Sbjct: 140 KSKPPKRDEKERKRRSPSPKPTK 162



 Score = 33.1 bits (74), Expect = 0.58
 Identities = 42/175 (24%), Positives = 62/175 (35%), Gaps = 23/175 (13%)

Query: 127 SPRRVRHGTPDPSPRKDRHDTPDPSPRRARHDTPDPSPLRGARHDSDTSPPRRIRHDSSD 186
           SP R RH     S  K +    D   R+ R  +P P+ +   R        R +  D   
Sbjct: 125 SPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLT------RNVTKDHIM 178

Query: 187 TSPPRRARHDSPDPSPPRRPQHNSSG-DCQKATDSDLSSPRHKQSPGHQDSDSDLSP--- 242
                  +    D    R   H S G  C +  + D +    K   G Q    +++    
Sbjct: 179 EIFSTYGKIKMIDMPVERMHPHLSKGYACVEFENPDEAEKALKHMDGGQIDGQEITATVV 238

Query: 243 ----PRNRPRHRSSDSDL---------SPPRRRQRTKSSDSDLSPPRRSQPPGKK 284
               PR  PR  S    +         SPPR R+R++S        RRS+ PG++
Sbjct: 239 LAPWPRPTPRRFSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRSPGRR 293


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,478,232
Number of Sequences: 37866
Number of extensions: 1512308
Number of successful extensions: 11978
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 920
Number of HSP's that attempted gapping in prelim test: 8094
Number of HSP's gapped (non-prelim): 3261
length of query: 485
length of database: 18,247,518
effective HSP length: 106
effective length of query: 379
effective length of database: 14,233,722
effective search space: 5394580638
effective search space used: 5394580638
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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