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Search of human proteins with 229576873
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|229576873 F-box and WD repeat domain containing 12 isoform 1
[Homo sapiens]
(464 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|229576873 F-box and WD repeat domain containing 12 isoform 1 ... 965 0.0
gi|229576906 F-box and WD repeat domain containing 12 isoform 3 ... 911 0.0
gi|229576894 F-box and WD repeat domain containing 12 isoform 2 ... 746 0.0
gi|206597470 neural precursor cell expressed, developmentally do... 41 0.003
gi|206597468 neural precursor cell expressed, developmentally do... 41 0.003
gi|23097254 neural precursor cell expressed, developmentally dow... 41 0.003
gi|206597465 neural precursor cell expressed, developmentally do... 41 0.003
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] 41 0.003
gi|27312027 F-box only protein 16 [Homo sapiens] 40 0.003
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 39 0.008
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 39 0.008
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 38 0.017
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 37 0.038
gi|4506399 RAE1 (RNA export 1, S.pombe) homolog [Homo sapiens] 37 0.038
gi|62739173 RAE1 (RNA export 1, S.pombe) homolog [Homo sapiens] 37 0.038
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H... 36 0.085
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 36 0.085
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 35 0.11
gi|157743247 F-box protein 45 [Homo sapiens] 35 0.14
gi|34485720 echinoderm microtubule associated protein like 5 [Ho... 34 0.32
gi|21536371 telomerase-associated protein 1 [Homo sapiens] 32 1.2
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H... 32 1.2
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H... 32 1.2
gi|59938780 WD repeat domain 31 isoform 1 [Homo sapiens] 32 1.6
gi|21687048 WD repeat domain 31 isoform 3 [Homo sapiens] 32 1.6
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 32 1.6
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 32 1.6
gi|111185922 F-box protein 36 [Homo sapiens] 32 1.6
gi|11545739 F-box and WD repeat domain containing 4 [Homo sapiens] 32 1.6
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 31 2.1
>gi|229576873 F-box and WD repeat domain containing 12 isoform 1
[Homo sapiens]
Length = 464
Score = 965 bits (2495), Expect = 0.0
Identities = 464/464 (100%), Positives = 464/464 (100%)
Query: 1 MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL 60
MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL
Sbjct: 1 MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL 60
Query: 61 GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDEQEKSIIC 120
GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDEQEKSIIC
Sbjct: 61 GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDEQEKSIIC 120
Query: 121 SVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDA 180
SVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDA
Sbjct: 121 SVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDA 180
Query: 181 LAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCS 240
LAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCS
Sbjct: 181 LAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCS 240
Query: 241 PDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLM 300
PDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLM
Sbjct: 241 PDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLM 300
Query: 301 SQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSG 360
SQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSG
Sbjct: 301 SQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSG 360
Query: 361 PYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCH 420
PYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCH
Sbjct: 361 PYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCH 420
Query: 421 LENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT 464
LENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT
Sbjct: 421 LENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT 464
>gi|229576906 F-box and WD repeat domain containing 12 isoform 3
[Homo sapiens]
Length = 445
Score = 911 bits (2355), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 30 KHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHTWKQFFLHQRRKELRLALAQPHNFIY 89
KHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHTWKQFFLHQRRKELRLALAQPHNFIY
Sbjct: 11 KHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHTWKQFFLHQRRKELRLALAQPHNFIY 70
Query: 90 KVTKNIAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHF 149
KVTKNIAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHF
Sbjct: 71 KVTKNIAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHF 130
Query: 150 SNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDA 209
SNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDA
Sbjct: 131 SNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDA 190
Query: 210 AGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPS 269
AGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPS
Sbjct: 191 AGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPS 250
Query: 270 EGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQA 329
EGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQA
Sbjct: 251 EGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQA 310
Query: 330 YEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVD 389
YEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVD
Sbjct: 311 YEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVD 370
Query: 390 PCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVR 449
PCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVR
Sbjct: 371 PCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVR 430
Query: 450 KVSDSSILVMYSLNT 464
KVSDSSILVMYSLNT
Sbjct: 431 KVSDSSILVMYSLNT 445
>gi|229576894 F-box and WD repeat domain containing 12 isoform 2
[Homo sapiens]
Length = 394
Score = 746 bits (1927), Expect = 0.0
Identities = 382/465 (82%), Positives = 387/465 (83%), Gaps = 72/465 (15%)
Query: 1 MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL 60
MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL
Sbjct: 1 MEIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHL 60
Query: 61 GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDEQEKSIIC 120
GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDE
Sbjct: 61 GTHTWKQFFLHQRRKELRLALAQPHNFIYKVTKNIAFETELAYLSGNRLTVDE------- 113
Query: 121 SVSPKQELCAWDVQEGTMIWS-SPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRD 179
QE ++I S SP QE + W+ Q+
Sbjct: 114 -------------QEKSIICSVSPKQE-----------------------LCAWDVQE-- 135
Query: 180 ALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHC 239
VGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHC
Sbjct: 136 --------------------------VGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHC 169
Query: 240 SPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITL 299
SPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITL
Sbjct: 170 SPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITL 229
Query: 300 MSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTS 359
MSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTS
Sbjct: 230 MSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTS 289
Query: 360 GPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCC 419
GPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCC
Sbjct: 290 GPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCC 349
Query: 420 HLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT 464
HLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT
Sbjct: 350 HLENTWHDHTTDSCISSVMCDNASIVLRVRKVSDSSILVMYSLNT 394
>gi|206597470 neural precursor cell expressed, developmentally
down-regulated 1 isoform c [Homo sapiens]
Length = 571
Score = 40.8 bits (94), Expect = 0.003
Identities = 54/240 (22%), Positives = 93/240 (38%), Gaps = 37/240 (15%)
Query: 115 EKSIICSVSPKQELCAWDVQEGT------MIWSSPVQEFHFSNLVTLPQMHLAITMDRKK 168
+KS++ SVS + WDV + + +P FS + L L +T+ K
Sbjct: 85 KKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNEL----LFVTIGLDK 140
Query: 169 TIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVT 228
I +++ + + L P ++ DG L +G + G IY + L L+ K
Sbjct: 141 RIILYDTSSKKLVKTLVADTPLTAVD--FMPDGATLAIGSSRGKIYQYDLRMLKSPVKTI 198
Query: 229 ----------AFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPS-----EGSV 273
AFQY VL S +K T ++ V ++ S +
Sbjct: 199 SAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPAT 258
Query: 274 PLSTFLPHKLCASA----------CWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGG 323
++T LP + ++ P+ N TL ++ +GK +F +FD T K + G
Sbjct: 259 SIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLG 318
>gi|206597468 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 40.8 bits (94), Expect = 0.003
Identities = 54/240 (22%), Positives = 93/240 (38%), Gaps = 37/240 (15%)
Query: 115 EKSIICSVSPKQELCAWDVQEGT------MIWSSPVQEFHFSNLVTLPQMHLAITMDRKK 168
+KS++ SVS + WDV + + +P FS + L L +T+ K
Sbjct: 174 KKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNEL----LFVTIGLDK 229
Query: 169 TIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVT 228
I +++ + + L P ++ DG L +G + G IY + L L+ K
Sbjct: 230 RIILYDTSSKKLVKTLVADTPLTAVD--FMPDGATLAIGSSRGKIYQYDLRMLKSPVKTI 287
Query: 229 ----------AFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPS-----EGSV 273
AFQY VL S +K T ++ V ++ S +
Sbjct: 288 SAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPAT 347
Query: 274 PLSTFLPHKLCASA----------CWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGG 323
++T LP + ++ P+ N TL ++ +GK +F +FD T K + G
Sbjct: 348 SIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLG 407
>gi|23097254 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 40.8 bits (94), Expect = 0.003
Identities = 54/240 (22%), Positives = 93/240 (38%), Gaps = 37/240 (15%)
Query: 115 EKSIICSVSPKQELCAWDVQEGT------MIWSSPVQEFHFSNLVTLPQMHLAITMDRKK 168
+KS++ SVS + WDV + + +P FS + L L +T+ K
Sbjct: 174 KKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNEL----LFVTIGLDK 229
Query: 169 TIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVT 228
I +++ + + L P ++ DG L +G + G IY + L L+ K
Sbjct: 230 RIILYDTSSKKLVKTLVADTPLTAVD--FMPDGATLAIGSSRGKIYQYDLRMLKSPVKTI 287
Query: 229 ----------AFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPS-----EGSV 273
AFQY VL S +K T ++ V ++ S +
Sbjct: 288 SAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPAT 347
Query: 274 PLSTFLPHKLCASA----------CWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGG 323
++T LP + ++ P+ N TL ++ +GK +F +FD T K + G
Sbjct: 348 SIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLG 407
>gi|206597465 neural precursor cell expressed, developmentally
down-regulated 1 isoform a [Homo sapiens]
Length = 667
Score = 40.8 bits (94), Expect = 0.003
Identities = 54/240 (22%), Positives = 93/240 (38%), Gaps = 37/240 (15%)
Query: 115 EKSIICSVSPKQELCAWDVQEGT------MIWSSPVQEFHFSNLVTLPQMHLAITMDRKK 168
+KS++ SVS + WDV + + +P FS + L L +T+ K
Sbjct: 181 KKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNEL----LFVTIGLDK 236
Query: 169 TIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVT 228
I +++ + + L P ++ DG L +G + G IY + L L+ K
Sbjct: 237 RIILYDTSSKKLVKTLVADTPLTAVD--FMPDGATLAIGSSRGKIYQYDLRMLKSPVKTI 294
Query: 229 ----------AFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPS-----EGSV 273
AFQY VL S +K T ++ V ++ S +
Sbjct: 295 SAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPAT 354
Query: 274 PLSTFLPHKLCASA----------CWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGG 323
++T LP + ++ P+ N TL ++ +GK +F +FD T K + G
Sbjct: 355 SIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDSGKNQDFSSFDDTGKSSLG 414
>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo
sapiens]
Length = 326
Score = 40.8 bits (94), Expect = 0.003
Identities = 17/45 (37%), Positives = 27/45 (60%)
Query: 3 IRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
+ LPD L IFS+L + +++S+V W R+ D +LWR + L
Sbjct: 5 VELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDL 49
>gi|27312027 F-box only protein 16 [Homo sapiens]
Length = 292
Score = 40.4 bits (93), Expect = 0.003
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Query: 4 RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTH 63
+LP + IFSFLD L + +QV HW +A+ D LW L+ NF+
Sbjct: 91 KLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLAELDQLWMLKCLRFNWYINFSPTPFEQG 150
Query: 64 TWKQFFLHQRRKELRL 79
WK+ ++ Q KEL +
Sbjct: 151 IWKKHYI-QMVKELHI 165
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 39.3 bits (90), Expect = 0.008
Identities = 22/43 (51%), Positives = 27/43 (62%)
Query: 5 LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
LPD L IFS L L LL+VS V K W R+A + LW++L L
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 39.3 bits (90), Expect = 0.008
Identities = 22/43 (51%), Positives = 27/43 (62%)
Query: 5 LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
LPD L IFS L L LL+VS V K W R+A + LW++L L
Sbjct: 100 LPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDL 142
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo
sapiens]
Length = 423
Score = 38.1 bits (87), Expect = 0.017
Identities = 18/44 (40%), Positives = 27/44 (61%)
Query: 4 RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
+LP L RIFSFLD+ L + +Q++K WN +A W+ + L
Sbjct: 14 KLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDL 57
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo
sapiens]
Length = 436
Score = 37.0 bits (84), Expect = 0.038
Identities = 18/44 (40%), Positives = 27/44 (61%)
Query: 4 RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
+LP L RIFSFLD+ L + +QV++ WN +A W+ + L
Sbjct: 27 KLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDL 70
>gi|4506399 RAE1 (RNA export 1, S.pombe) homolog [Homo sapiens]
Length = 368
Score = 37.0 bits (84), Expect = 0.038
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 7/68 (10%)
Query: 131 WDVQEGTMIW----SSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPM 186
WD+ I +PV+ H+ + P +T KT+K W+ + + + VL +
Sbjct: 113 WDLSSNQAIQIAQHDAPVKTIHW---IKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQL 169
Query: 187 PQPCYCME 194
P+ CYC +
Sbjct: 170 PERCYCAD 177
>gi|62739173 RAE1 (RNA export 1, S.pombe) homolog [Homo sapiens]
Length = 368
Score = 37.0 bits (84), Expect = 0.038
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 7/68 (10%)
Query: 131 WDVQEGTMIW----SSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPM 186
WD+ I +PV+ H+ + P +T KT+K W+ + + + VL +
Sbjct: 113 WDLSSNQAIQIAQHDAPVKTIHW---IKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQL 169
Query: 187 PQPCYCME 194
P+ CYC +
Sbjct: 170 PERCYCAD 177
>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
sapiens]
Length = 532
Score = 35.8 bits (81), Expect = 0.085
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 2 EIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLG 61
+I+LP IF +LD L + +QV+K W IA+ + LW L Q + + +
Sbjct: 50 DIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQE---GHLPDSSIS 106
Query: 62 THT-WKQFFLHQRRKE 76
++ WK F R KE
Sbjct: 107 DYSCWKLIFQECRAKE 122
>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
sapiens]
Length = 598
Score = 35.8 bits (81), Expect = 0.085
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 2 EIRLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLG 61
+I+LP IF +LD L + +QV+K W IA+ + LW L Q + + +
Sbjct: 116 DIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQE---GHLPDSSIS 172
Query: 62 THT-WKQFFLHQRRKE 76
++ WK F R KE
Sbjct: 173 DYSCWKLIFQECRAKE 188
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 35.4 bits (80), Expect = 0.11
Identities = 17/44 (38%), Positives = 27/44 (61%)
Query: 4 RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSL 47
RLPD ++ +IFSFL L + ++V + W +A LWR++ L
Sbjct: 116 RLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRL 159
>gi|157743247 F-box protein 45 [Homo sapiens]
Length = 286
Score = 35.0 bits (79), Expect = 0.14
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Query: 4 RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSD---YLWRSL 45
RLP L+ +FS+L+L L + V KHW R D +WRSL
Sbjct: 38 RLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSL 82
>gi|34485720 echinoderm microtubule associated protein like 5 [Homo
sapiens]
Length = 1977
Score = 33.9 bits (76), Expect = 0.32
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Query: 152 LVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAG 211
L P LA+T +++++W+ D +A M +P C A + DG L +G G
Sbjct: 331 LAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRC--AAVNADGIHLALGMKDG 388
Query: 212 DIYTFTLPGLRDVSKV 227
+FT+ +RD+++V
Sbjct: 389 ---SFTVLRVRDMTEV 401
>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
Length = 2627
Score = 32.0 bits (71), Expect = 1.2
Identities = 19/92 (20%), Positives = 36/92 (39%), Gaps = 2/92 (2%)
Query: 131 WDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPC 190
WD+Q G + + ++ + P L T+ +K+W+ P+
Sbjct: 1744 WDLQHGCRVLQTKAHQYQITGCCLSPDCRLLATVCLGGCLKLWDTVRGQLAFQHTYPKSL 1803
Query: 191 YCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLR 222
C+ + +G + G AG I F + GL+
Sbjct: 1804 NCVAFH--PEGQVIATGSWAGSISFFQVDGLK 1833
>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
sapiens]
Length = 565
Score = 32.0 bits (71), Expect = 1.2
Identities = 15/46 (32%), Positives = 25/46 (54%)
Query: 5 LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRW 50
LP + IFS+L+ L + SQV+ W+++ + LW+ L W
Sbjct: 82 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHW 127
>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
sapiens]
Length = 691
Score = 32.0 bits (71), Expect = 1.2
Identities = 15/46 (32%), Positives = 25/46 (54%)
Query: 5 LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRW 50
LP + IFS+L+ L + SQV+ W+++ + LW+ L W
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHW 253
>gi|59938780 WD repeat domain 31 isoform 1 [Homo sapiens]
Length = 367
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/80 (22%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
Query: 115 EKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWN 174
+ S +C+ S L WDV G + + V ++L +P+ + KT+++W+
Sbjct: 157 DSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWD 216
Query: 175 CQDRDALAVLPMPQ--PCYC 192
+ + P Q YC
Sbjct: 217 SRGLQVAHMFPAKQHIQTYC 236
>gi|21687048 WD repeat domain 31 isoform 3 [Homo sapiens]
Length = 366
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/80 (22%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
Query: 115 EKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWN 174
+ S +C+ S L WDV G + + V ++L +P+ + KT+++W+
Sbjct: 156 DSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWD 215
Query: 175 CQDRDALAVLPMPQ--PCYC 192
+ + P Q YC
Sbjct: 216 SRGLQVAHMFPAKQHIQTYC 235
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
[Homo sapiens]
Length = 690
Score = 31.6 bits (70), Expect = 1.6
Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 5 LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHT 64
LP+ A+ +IF +L L ++ QVN W + + LW ++ N T
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFS--SVKNVIPDKYIVST 215
Query: 65 WKQFFLHQRRKELRLALAQPHNF 87
+++ L+ R R L +P F
Sbjct: 216 LQRWRLNVLRLNFRGCLLRPKTF 238
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
[Homo sapiens]
Length = 735
Score = 31.6 bits (70), Expect = 1.6
Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 5 LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTHT 64
LP+ A+ +IF +L L ++ QVN W + + LW ++ N T
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFS--SVKNVIPDKYIVST 215
Query: 65 WKQFFLHQRRKELRLALAQPHNF 87
+++ L+ R R L +P F
Sbjct: 216 LQRWRLNVLRLNFRGCLLRPKTF 238
>gi|111185922 F-box protein 36 [Homo sapiens]
Length = 188
Score = 31.6 bits (70), Expect = 1.6
Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 4 RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLSLQRWDCSNFTNQHLGTH 63
RL D L I S+LDL + ++ Q + + ++ SD LW + D + L
Sbjct: 96 RLSDDLLLTIISYLDLEDIARLCQTSHRFAKLCMSDKLWEQIVQSTCDTITPDVRALAED 155
Query: 64 T-WKQFFLH---QRRKELR 78
T W+Q F Q +++LR
Sbjct: 156 TGWRQLFFTNKLQLQRQLR 174
>gi|11545739 F-box and WD repeat domain containing 4 [Homo
sapiens]
Length = 412
Score = 31.6 bits (70), Expect = 1.6
Identities = 16/43 (37%), Positives = 25/43 (58%)
Query: 4 RLPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWRSLS 46
RLP+ L I S+LD+ L +++QV + R D LWR ++
Sbjct: 30 RLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIA 72
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 31.2 bits (69), Expect = 2.1
Identities = 14/39 (35%), Positives = 22/39 (56%)
Query: 5 LPDLALKRIFSFLDLFGLLQVSQVNKHWNRIADSDYLWR 43
LP + SFL+ LLQ +Q ++W +A+ + LWR
Sbjct: 166 LPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWR 204
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.135 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,839,244
Number of Sequences: 37866
Number of extensions: 780460
Number of successful extensions: 2118
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2072
Number of HSP's gapped (non-prelim): 78
length of query: 464
length of database: 18,247,518
effective HSP length: 106
effective length of query: 358
effective length of database: 14,233,722
effective search space: 5095672476
effective search space used: 5095672476
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.