Guide to the Human Genome
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Search of human proteins with 229331967

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens]
         (552 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens]                   1110   0.0  
gi|229331971 RIO kinase 2 isoform 2 [Homo sapiens]                    945   0.0  
gi|23510356 RIO kinase 1 isoform 1 [Homo sapiens]                      61   2e-09
gi|22325377 sudD suppressor of bimD6 homolog [Homo sapiens]            50   7e-06
gi|23510358 RIO kinase 1 isoform 2 [Homo sapiens]                      48   2e-05
gi|118600963 Nik related kinase [Homo sapiens]                         41   0.003
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                40   0.006
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 40   0.006
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    40   0.007
gi|207029299 NIMA-related kinase 10 isoform 3 [Homo sapiens]           39   0.012
gi|224589071 BMS1-like, ribosome assembly protein [Homo sapiens]       39   0.016
gi|162287219 prune homolog 2 [Homo sapiens]                            36   0.10 
gi|55741661 hypothetical protein LOC57653 [Homo sapiens]               36   0.10 
gi|15451902 mitogen-activated protein kinase kinase kinase kinas...    35   0.14 
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     34   0.31 
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     34   0.31 
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    34   0.31 
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    34   0.31 
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    34   0.31 
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    34   0.31 
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    34   0.31 
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    34   0.31 
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    34   0.31 
gi|4504487 histidine rich calcium binding protein precursor [Hom...    34   0.40 
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]            33   0.52 
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]            33   0.52 
gi|118421089 chromodomain helicase DNA binding protein 2 isoform...    33   0.52 
gi|110611184 chromodomain helicase DNA binding protein 2 isoform...    33   0.52 
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H...    33   0.68 
gi|4506067 protein kinase C, alpha [Homo sapiens]                      33   0.89 

>gi|229331967 RIO kinase 2 isoform 1 [Homo sapiens]
          Length = 552

 Score = 1110 bits (2871), Expect = 0.0
 Identities = 552/552 (100%), Positives = 552/552 (100%)

Query: 1   MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPGSLIASIASLKHGGCNKVLRELVKHK 60
           MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPGSLIASIASLKHGGCNKVLRELVKHK
Sbjct: 1   MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPGSLIASIASLKHGGCNKVLRELVKHK 60

Query: 61  LIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQF 120
           LIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQF
Sbjct: 61  LIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQF 120

Query: 121 ALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPID 180
           ALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPID
Sbjct: 121 ALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPID 180

Query: 181 YNRHAVVMELINGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDESD 240
           YNRHAVVMELINGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDESD
Sbjct: 181 YNRHAVVMELINGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDESD 240

Query: 241 HITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDVEV 300
           HITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDVEV
Sbjct: 241 HITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDVEV 300

Query: 301 SASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLE 360
           SASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLE
Sbjct: 301 SASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLE 360

Query: 361 ESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEK 420
           ESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEK
Sbjct: 361 ESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEK 420

Query: 421 NRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFRDEENVGAMNQYRTR 480
           NRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFRDEENVGAMNQYRTR
Sbjct: 421 NRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFRDEENVGAMNQYRTR 480

Query: 481 TLSITSSGSAVSCSTIPPELVKQKVKRQLTKQQKSAVRRRLQKGEANIFTKQRRENMQNI 540
           TLSITSSGSAVSCSTIPPELVKQKVKRQLTKQQKSAVRRRLQKGEANIFTKQRRENMQNI
Sbjct: 481 TLSITSSGSAVSCSTIPPELVKQKVKRQLTKQQKSAVRRRLQKGEANIFTKQRRENMQNI 540

Query: 541 KSSLEAASFWGE 552
           KSSLEAASFWGE
Sbjct: 541 KSSLEAASFWGE 552


>gi|229331971 RIO kinase 2 isoform 2 [Homo sapiens]
          Length = 474

 Score =  945 bits (2443), Expect = 0.0
 Identities = 466/466 (100%), Positives = 466/466 (100%)

Query: 1   MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPGSLIASIASLKHGGCNKVLRELVKHK 60
           MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPGSLIASIASLKHGGCNKVLRELVKHK
Sbjct: 1   MGKVNVAKLRYMSRDDFRVLTAVEMGMKNHEIVPGSLIASIASLKHGGCNKVLRELVKHK 60

Query: 61  LIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQF 120
           LIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQF
Sbjct: 61  LIAWERTKTVQGYRLTNAGYDYLALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQF 120

Query: 121 ALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPID 180
           ALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPID
Sbjct: 121 ALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPID 180

Query: 181 YNRHAVVMELINGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDESD 240
           YNRHAVVMELINGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDESD
Sbjct: 181 YNRHAVVMELINGYPLCQIHHVEDPASVYDEAMELIVKLANHGLIHGDFNEFNLILDESD 240

Query: 241 HITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDVEV 300
           HITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDVEV
Sbjct: 241 HITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDVEV 300

Query: 301 SASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLE 360
           SASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLE
Sbjct: 301 SASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLE 360

Query: 361 ESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEK 420
           ESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEK
Sbjct: 361 ESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEK 420

Query: 421 NRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFR 466
           NRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFR
Sbjct: 421 NRTENYNRQDGQRVQGGVPAGSDEYEDECPHLIALSSLNREFRPFR 466


>gi|23510356 RIO kinase 1 isoform 1 [Homo sapiens]
          Length = 568

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 51/210 (24%), Positives = 97/210 (46%), Gaps = 24/210 (11%)

Query: 83  LALKTLSSRQVVESVGNQMGVGKESDIYIVANEEGQQFALKLHRLGRTSFRNLKNKRDY- 141
           + L  + +R ++  +   +  GKE+++Y  +   G+  A+K+++   TS    K++  Y 
Sbjct: 168 MILFKMLTRGIITEINGCISTGKEANVYHASTANGESRAIKIYK---TSILVFKDRDKYV 224

Query: 142 ---HKHRHNV---SWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNRHAVVMELI--NG 193
               + RH     +   + +  A KE   +  L   + P P+PI    H +VM  I  + 
Sbjct: 225 SGEFRFRHGYCKGNPRKMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDD 284

Query: 194 YPLCQIHHVEDPASVYDEAMELIVKLANH--------GLIHGDFNEFNLILDESDHITMI 245
            P   + +V+   S   +A EL +++  +         L+H D +EFN++      + +I
Sbjct: 285 MPAPLLKNVQLSES---KARELYLQVIQYMRRMYQDARLVHADLSEFNMLY-HGGGVYII 340

Query: 246 DFPQMVSTSHPNAEWYFDRDVKCIKDFFMK 275
           D  Q V   HP+A  +  +D   + DFFM+
Sbjct: 341 DVSQSVEHDHPHALEFLRKDCANVNDFFMR 370


>gi|22325377 sudD suppressor of bimD6 homolog [Homo sapiens]
          Length = 519

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 65/286 (22%), Positives = 118/286 (41%), Gaps = 33/286 (11%)

Query: 73  YRLTNAGYDYLALKTLSSRQ---VVESVGNQMGVGKESDIYIVANEEGQQFALKLHRLGR 129
           Y++ N+G        +S+ +   V  + G  M   KE D  ++  E     A+K+ +   
Sbjct: 242 YKMVNSGMLETITGCISTGKESVVFHAYGGSMEDEKE-DSKVIPTE----CAIKVFKTTL 296

Query: 130 TSFRNL-KNKRDYHKHRHNVSWLY---LSRLSAMKEFAYMKALYERKFPVPKPIDYNRHA 185
             F+N  K  +D  + +   S L    + R+ A KE   +  +     P P  +   +H 
Sbjct: 297 NEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLARMQRAGIPCPTVVLLKKHI 356

Query: 186 VVMELI--NGYPLCQIHHV----EDPASVYDEAMELIVKLANH-GLIHGDFNEFNLILDE 238
           +VM  I  +  P  ++  V    E+    Y + + L+ +L +   L+H D +E+N++   
Sbjct: 357 LVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLW-H 415

Query: 239 SDHITMIDFPQMVSTSHPNAEWYFDRDVKCIKDFFMKRFSYESELFPTFKDIRREDTLDV 298
           +  + +ID  Q V  +HP+   +  RD + +  FF K            K+   E  L  
Sbjct: 416 AGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQK---------GGVKEALSERELFN 466

Query: 299 EVSASGYTKEMQAD----DELLHPLGPDDKNIETKEGSEFSFSDGE 340
            VS    T + +AD     E L  +  D      ++ + F   DG+
Sbjct: 467 AVSGLNITADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDDGD 512


>gi|23510358 RIO kinase 1 isoform 2 [Homo sapiens]
          Length = 327

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 36/128 (28%), Positives = 60/128 (46%), Gaps = 14/128 (10%)

Query: 158 AMKEFAYMKALYERKFPVPKPIDYNRHAVVMELI--NGYPLCQIHHVEDPASVYDEAMEL 215
           A KE   +  L   + P P+PI    H +VM  I  +  P   + +V+   S   +A EL
Sbjct: 6   AEKEMRNLIRLNTAEIPCPEPIMLRSHVLVMSFIGKDDMPAPLLKNVQLSES---KAREL 62

Query: 216 IVKLANH--------GLIHGDFNEFNLILDESDHITMIDFPQMVSTSHPNAEWYFDRDVK 267
            +++  +         L+H D +EFN++      + +ID  Q V   HP+A  +  +D  
Sbjct: 63  YLQVIQYMRRMYQDARLVHADLSEFNMLY-HGGGVYIIDVSQSVEHDHPHALEFLRKDCA 121

Query: 268 CIKDFFMK 275
            + DFFM+
Sbjct: 122 NVNDFFMR 129


>gi|118600963 Nik related kinase [Homo sapiens]
          Length = 1582

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 41/217 (18%), Positives = 91/217 (41%), Gaps = 29/217 (13%)

Query: 96  SVGNQMGVGKESDIYIVANEEGQQF-ALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYL- 153
           S+   +G+G    IY+  +E+   F A+K+    +T    +  +   +K++ +V W Y  
Sbjct: 26  SLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARKTPLPEIGRRVRVNKYQKSVGWRYSD 85

Query: 154 ------SRLSAMKEFAYMK---ALYERKFPVPKPIDYNRHAVVMELINGYPLCQIHHVED 204
                 + L+ ++++++ K   + Y   F +  P   ++  +VMEL     +  +  +  
Sbjct: 86  EEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAGSVTDVVRMTS 145

Query: 205 PASVYD--------EAMELIVKLANHGLIHGDFNEFNLILDESDHITMIDFPQMVSTSHP 256
             S+ +        E ++ +  L  H +IH D    N++L  +  + ++DF      S  
Sbjct: 146 NQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSRT 205

Query: 257 NAE---------WYFDRDVKCIKDFFMKRFSYESELF 284
           N           W     + C +D   + + Y S+++
Sbjct: 206 NGRRNSFIGTPYWMAPEVIDCDED-PRRSYDYRSDVW 241


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 9/163 (5%)

Query: 293 EDTLDVEVSAS-GYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSE 351
           ED L+ E     G TKE + DD        D    ++++GSE  F +  + +  +  GSE
Sbjct: 522 EDDLNKESEEEVGPTKESEEDDSEKES-DEDCSEKQSEDGSEREFEENGLEKDLDEEGSE 580

Query: 352 NESERNCLE------ESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKG 405
            E   N L+      +SE       G  E++ ++  SE   D  S E  E     E++  
Sbjct: 581 KELHENVLDKELEENDSENSEFEDDGS-EKVLDEEGSEREFDEDSDEKEEEEDTYEKVFD 639

Query: 406 QVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEYEDE 448
              +     E+++EK       + +       +   SD+ EDE
Sbjct: 640 DESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDE 682



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 34/131 (25%), Positives = 58/131 (44%), Gaps = 14/131 (10%)

Query: 322 DDKNIE-TKEGSEFSFSDGEVAEKAEVYGSENESERNC--LEESEGCYCRSSGDPEQIKE 378
           D+K  E T++G EF   +G     A+    E E+E  C   E  EGC       P++  E
Sbjct: 427 DEKKFEKTEDGGEFE--EGASENNAKESSPEKEAEEGCPEKESEEGC-------PKRGFE 477

Query: 379 DSLSE-ESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGG 437
            S S+ ES +      +E +   +E K + ++N+   E    K   ++ N++  + V   
Sbjct: 478 GSCSQKESEEGNPVRGSEEDSPKKESKKKTLKND-CEENGLAKESEDDLNKESEEEVGPT 536

Query: 438 VPAGSDEYEDE 448
             +  D+ E E
Sbjct: 537 KESEEDDSEKE 547


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 9/163 (5%)

Query: 293 EDTLDVEVSAS-GYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSE 351
           ED L+ E     G TKE + DD        D    ++++GSE  F +  + +  +  GSE
Sbjct: 522 EDDLNKESEEEVGPTKESEEDDSEKES-DEDCSEKQSEDGSEREFEENGLEKDLDEEGSE 580

Query: 352 NESERNCLE------ESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKG 405
            E   N L+      +SE       G  E++ ++  SE   D  S E  E     E++  
Sbjct: 581 KELHENVLDKELEENDSENSEFEDDGS-EKVLDEEGSEREFDEDSDEKEEEEDTYEKVFD 639

Query: 406 QVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEYEDE 448
              +     E+++EK       + +       +   SD+ EDE
Sbjct: 640 DESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDE 682



 Score = 32.7 bits (73), Expect = 0.89
 Identities = 34/131 (25%), Positives = 58/131 (44%), Gaps = 14/131 (10%)

Query: 322 DDKNIE-TKEGSEFSFSDGEVAEKAEVYGSENESERNC--LEESEGCYCRSSGDPEQIKE 378
           D+K  E T++G EF   +G     A+    E E+E  C   E  EGC       P++  E
Sbjct: 427 DEKKFEKTEDGGEFE--EGASENNAKESSPEKEAEEGCPEKESEEGC-------PKRGFE 477

Query: 379 DSLSE-ESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGG 437
            S S+ ES +      +E +   +E K + ++N+   E    K   ++ N++  + V   
Sbjct: 478 GSCSQKESEEGNPVRGSEEDSPKKESKKKTLKND-CEENGLAKESEDDLNKESEEEVGPT 536

Query: 438 VPAGSDEYEDE 448
             +  D+ E E
Sbjct: 537 KESEEDDSEKE 547


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 20/127 (15%)

Query: 323 DKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKEDSLS 382
           ++N E +EG E    +GE          E E +R   EE EG   +  G+ E+++ +   
Sbjct: 722 ERNQEMEEGGEEEHGEGE----------EEEGDREEEEEKEG-EGKEEGEGEEVEGEREK 770

Query: 383 EESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGG-VPAG 441
           EE       E  +  +A +E KG+  E     E  EE+       +++G  V+GG V  G
Sbjct: 771 EEG------ERKKEERAGKEEKGE--EEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822

Query: 442 SDEYEDE 448
             E E+E
Sbjct: 823 KGEREEE 829



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 7/115 (6%)

Query: 327  ETKEGSEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKEDSLSEESA 386
            E +EG E    +GE  E+ E  G E E E     E EG      G+ E+ +E+   E   
Sbjct: 991  EEEEGEEEGEEEGEGEEEGEGEG-EEEEEGEVEGEVEGEEGEGEGEEEEGEEEG-EEREK 1048

Query: 387  DARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAG 441
            +    E     +  EE +G+  E        EE  R +    +   +++G V  G
Sbjct: 1049 EGEGEENRRNREEEEEEEGKYQETG-----EEENERQDGEEYKKVSKIKGSVKYG 1098



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 35/156 (22%), Positives = 60/156 (38%), Gaps = 22/156 (14%)

Query: 322  DDKNIETKEGSEFSFSDGEVAEKAEV-----------YGSENESERNCLE---ESEGCYC 367
            +++  E  EG E    +GE  E+ EV            G E E E    E   E EG   
Sbjct: 996  EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055

Query: 368  RSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYN 427
            R + + E+ +E    E   +    +  E  + + +IKG V      T   +    T+   
Sbjct: 1056 RRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNG 1115

Query: 428  RQ-------DGQRVQGGVPAGSDEY-EDECPHLIAL 455
            ++         +R+    P+GS ++  +  PH + L
Sbjct: 1116 KEQRSKMPVQSKRLLKNGPSGSKKFWNNVLPHYLEL 1151



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 37/158 (23%), Positives = 58/158 (36%), Gaps = 7/158 (4%)

Query: 291 RREDTLDVEVSASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGS 350
           ++E+    E        + + ++E     G + +     EG E     GE  E+ E    
Sbjct: 776 KKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEG 835

Query: 351 ENESERNCLEESEGCYCRSSGDPEQIKEDSLSEESADARSFEMTEFNQALEEIKGQVVEN 410
           E E      EE EG      G  E+  E+   EE  +    E  E     EE +G+  E 
Sbjct: 836 EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE-----EEGEGE-GEE 889

Query: 411 NSVTEFSEEKNRTENYNRQDGQ-RVQGGVPAGSDEYED 447
               E  EE+   E     +G+   + G   G +E E+
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927


>gi|207029299 NIMA-related kinase 10 isoform 3 [Homo sapiens]
          Length = 712

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 25/163 (15%)

Query: 99  NQMGVGKESDIYIVANEEGQQF-ALKLHRLGRTSFRNLKNKRDYHKHRHNVSWLYLSRLS 157
           + +G G    +Y V    GQ   A+K   L   +F   K+K+D      N+    +S L+
Sbjct: 523 DHLGSGAFGCVYKVRKHSGQNLLAMKEVNLHNPAFG--KDKKDRDSSVRNI----VSELT 576

Query: 158 AMKEFAYMKAL--YERKFPVPKPIDYNRHAVVMELINGYPLCQI-------HHVEDPASV 208
            +KE  Y   +  Y + F     ++ +R  +VMELI G PL +        HH      +
Sbjct: 577 IIKEQLYHPNIVRYYKTF-----LENDRLYIVMELIEGAPLGEHFSSLKEKHHHFTEERL 631

Query: 209 YDEAMELIVKLA----NHGLIHGDFNEFNLILDESDHITMIDF 247
           +   ++L + L        ++H D    N++L + D +T+ DF
Sbjct: 632 WKIFIQLCLALRYLHKEKRIVHRDLTPNNIMLGDKDKVTVTDF 674


>gi|224589071 BMS1-like, ribosome assembly protein [Homo sapiens]
          Length = 1282

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 40/184 (21%), Positives = 88/184 (47%), Gaps = 28/184 (15%)

Query: 279 YESELFPTFKDIRR----EDTLDVEVSASGYTKEMQADDELLHPLGPDDKNIE----TKE 330
           ++ E+ PT + ++       T+D ++++S  T  + +D +   PLG +D + +     KE
Sbjct: 362 FQDEVGPTHELVQSLISTHSTIDAKMASSRVT--LFSDSK---PLGSEDIDNQGLMMPKE 416

Query: 331 GSEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKEDSLSEESADARS 390
             +   + G +  KA ++G E+ES  +  EE +        + + ++  S  EE+ +  +
Sbjct: 417 EKQMDLNTGRMRRKA-IFGDEDESGDSDDEEDD-----EMSEDDGLENGSSDEEAEEEEN 470

Query: 391 FEMTEFNQALEEIKGQVVENNSVTE-----FSEEKNRTENYNRQDGQRVQGGVPAGSDEY 445
            EMT+   A++ IK + +E    +E     F++  +  E  + ++G+  +    A     
Sbjct: 471 AEMTDQYMAVKGIKRRKLELEEDSEMDLPAFADSDDDLERSSAEEGEAEE----ADESSE 526

Query: 446 EDEC 449
           E++C
Sbjct: 527 EEDC 530


>gi|162287219 prune homolog 2 [Homo sapiens]
          Length = 3088

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 30/140 (21%), Positives = 55/140 (39%), Gaps = 9/140 (6%)

Query: 301  SASGYTKEMQADDELLHPLGPDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLE 360
            +ASG +++ Q+D EL         ++   E  E     G+++  A  +  + E     LE
Sbjct: 1351 NASGISEKGQSDQEL--------SSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLE 1402

Query: 361  ESEGCYCRSSGDPEQ-IKEDSLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEE 419
              EG Y   S D +  +  D+L  +    +       +    E    +     V+   ++
Sbjct: 1403 YEEGSYNLDSRDVQTGMSADNLQPKDTHEKHLMSQRNSGETTETSDGMNFTKYVSVPEKD 1462

Query: 420  KNRTENYNRQDGQRVQGGVP 439
              +TE  N  + + V GG P
Sbjct: 1463 LEKTEECNFLEPENVGGGPP 1482


>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
          Length = 1646

 Score = 35.8 bits (81), Expect = 0.10
 Identities = 56/242 (23%), Positives = 88/242 (36%), Gaps = 39/242 (16%)

Query: 324  KNIETKEGS-------EFSFSDG-EVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQ 375
            K +  K+GS       E S S G   A   E    EN+ E       E    +    P  
Sbjct: 804  KKLRKKQGSKEDMTRSEESISSGTSTARSVEEVEEENDQEMESFITEE-VLGQQKKSPLH 862

Query: 376  IKEDSLSEESADARSFEMTEFNQAL------EEIKGQ------VVENNSVTEFSEEKNRT 423
             K D   E S         E   +L      E +KGQ        E +   E  EE+   
Sbjct: 863  AKMDESKEGSIQGLEEMQVEREGSLNPSLNEENVKGQGEKKEESEEEDEKEEEEEEEKLE 922

Query: 424  ENYNRQDGQRVQGGVPAGSDE----------YEDECPHLIALSSLNREFRPFRDEENVGA 473
            E    ++ Q  Q  +  G +E          YED     I+  +    F P  +E    +
Sbjct: 923  EEKEEKEAQEEQESLSVGEEEDKEEGLEEIYYEDMESFTISSGNTYFVFVPLEEEHCRKS 982

Query: 474  MNQYRTRTLSITSSGSAVSCSTIPPELVKQKVKRQL-------TKQQKSAVRRRLQKGEA 526
             + +    ++ TSS   +   TIP  L+ + +K+QL       + ++ +++  RL+K  A
Sbjct: 983  HSTFSAMFINDTSSAKFIEQVTIPSRLILE-IKKQLFSEGGNFSPKEINSLCSRLEKEAA 1041

Query: 527  NI 528
             I
Sbjct: 1042 RI 1043


>gi|15451902 mitogen-activated protein kinase kinase kinase kinase 3
           [Homo sapiens]
          Length = 894

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query: 186 VVMELINGYPLCQIHHVEDPAS------VYDEAMELIVKLANHGLIHGDFNEFNLILDES 239
           + ME   G  L  I+HV  P S      V  E ++ +  L + G +H D    N++L ++
Sbjct: 88  ICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDN 147

Query: 240 DHITMIDF 247
            H+ + DF
Sbjct: 148 GHVKLADF 155


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 12/134 (8%)

Query: 332 SEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKED------SLSEES 385
           SE   S  E +      GSE E E    EE EG     S + E+ +E+      S SEE+
Sbjct: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 319

Query: 386 ADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGS--- 442
           ++  + E++E  + + E + +  EN+ +       +R    + +  + V  G P  S   
Sbjct: 320 SEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALT 377

Query: 443 -DEYEDECPHLIAL 455
             +Y  + P L+ +
Sbjct: 378 EGDYVPDSPALLPI 391


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 12/134 (8%)

Query: 332 SEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKED------SLSEES 385
           SE   S  E +      GSE E E    EE EG     S + E+ +E+      S SEE+
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329

Query: 386 ADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGS--- 442
           ++  + E++E  + + E + +  EN+ +       +R    + +  + V  G P  S   
Sbjct: 330 SEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALT 387

Query: 443 -DEYEDECPHLIAL 455
             +Y  + P L+ +
Sbjct: 388 EGDYVPDSPALLPI 401


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 9/134 (6%)

Query: 332 SEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKED------SLSEES 385
           SE   S  E +      GSE E E    EE EG     S + E+ +E+      S SEE+
Sbjct: 261 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 320

Query: 386 ADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEY 445
           ++  + E++E  + + E + +  EN+ +       +R    + +  + V  G P  S   
Sbjct: 321 SEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALT 378

Query: 446 E-DECPHLIALSSL 458
           E D  P   ALS +
Sbjct: 379 EGDYVPDSPALSPI 392


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 9/134 (6%)

Query: 332 SEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKED------SLSEES 385
           SE   S  E +      GSE E E    EE EG     S + E+ +E+      S SEE+
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329

Query: 386 ADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEY 445
           ++  + E++E  + + E + +  EN+ +       +R    + +  + V  G P  S   
Sbjct: 330 SEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALT 387

Query: 446 E-DECPHLIALSSL 458
           E D  P   ALS +
Sbjct: 388 EGDYVPDSPALSPI 401


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 9/134 (6%)

Query: 332 SEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKED------SLSEES 385
           SE   S  E +      GSE E E    EE EG     S + E+ +E+      S SEE+
Sbjct: 238 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 297

Query: 386 ADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEY 445
           ++  + E++E  + + E + +  EN+ +       +R    + +  + V  G P  S   
Sbjct: 298 SEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALT 355

Query: 446 E-DECPHLIALSSL 458
           E D  P   ALS +
Sbjct: 356 EGDYVPDSPALSPI 369


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 9/134 (6%)

Query: 332 SEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKED------SLSEES 385
           SE   S  E +      GSE E E    EE EG     S + E+ +E+      S SEE+
Sbjct: 227 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 286

Query: 386 ADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEY 445
           ++  + E++E  + + E + +  EN+ +       +R    + +  + V  G P  S   
Sbjct: 287 SEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALT 344

Query: 446 E-DECPHLIALSSL 458
           E D  P   ALS +
Sbjct: 345 EGDYVPDSPALSPI 358


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 9/134 (6%)

Query: 332 SEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKED------SLSEES 385
           SE   S  E +      GSE E E    EE EG     S + E+ +E+      S SEE+
Sbjct: 16  SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 75

Query: 386 ADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEY 445
           ++  + E++E  + + E + +  EN+ +       +R    + +  + V  G P  S   
Sbjct: 76  SEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALT 133

Query: 446 E-DECPHLIALSSL 458
           E D  P   ALS +
Sbjct: 134 EGDYVPDSPALSPI 147


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 9/134 (6%)

Query: 332 SEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKED------SLSEES 385
           SE   S  E +      GSE E E    EE EG     S + E+ +E+      S SEE+
Sbjct: 272 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 331

Query: 386 ADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPAGSDEY 445
           ++  + E++E  + + E + +  EN+ +       +R    + +  + V  G P  S   
Sbjct: 332 SEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALT 389

Query: 446 E-DECPHLIALSSL 458
           E D  P   ALS +
Sbjct: 390 EGDYVPDSPALSPI 403


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 50/230 (21%), Positives = 93/230 (40%), Gaps = 25/230 (10%)

Query: 325 NIET-KEGSEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKEDSLSE 383
           NIE+  E  + SF    VA+K +    E E ++   E+++    +   + E  K+D  S+
Sbjct: 211 NIESGNEDDDASFKIKTVAQK-KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQ-SK 268

Query: 384 ESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRT--------ENYNRQDGQRVQ 435
           +    R FE        E +K +V  +  V   SEEK  T        E   ++  ++ +
Sbjct: 269 QKESQRKFEE-------ETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKK 321

Query: 436 GGVPAGSDEYEDECPHLIALSSLNREFRPFRDEENVGAMNQYRTRTLSITSSGSAVSCST 495
            G     ++ + + P    + ++       ++EE      Q R     I       +   
Sbjct: 322 KGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEE----RQKREEEERIKRLEELEAKRK 377

Query: 496 IPPELVKQKVKRQLTKQQKSAVRRRLQKGEANIFTKQRRENMQNIKSSLE 545
               L ++K +R   K+QK   R+   K E  + TK +RE     +++L+
Sbjct: 378 EEERLEQEKRER---KKQKEKERKERLKKEGKLLTKSQREARARAEATLK 424



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 20/91 (21%), Positives = 41/91 (45%)

Query: 321 PDDKNIETKEGSEFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKEDS 380
           P+++  E +E  E   S+ E  E+ E  GSE + E   + + +         P +     
Sbjct: 531 PEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSD 590

Query: 381 LSEESADARSFEMTEFNQALEEIKGQVVENN 411
              +S D R+ E   +++A   I+ + +E++
Sbjct: 591 SEYDSDDDRTKEERAYDKAKRRIEKRRLEHS 621


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 33.9 bits (76), Expect = 0.40
 Identities = 32/130 (24%), Positives = 47/130 (36%), Gaps = 2/130 (1%)

Query: 322 DDKNIETKEGS-EFSFSDGEVAEKAEVYGSENESERNCLEESEGCYCRSSGDPEQIKEDS 380
           ++K  E   GS E      E  EK   +GS ++ +    EE  G       + E+ KE+ 
Sbjct: 484 EEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEE 543

Query: 381 LSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVPA 440
             EE  + R  E  E    L     +  E        +E   T   N  D +   GG  +
Sbjct: 544 EEEEDEERRE-ERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAGGASS 602

Query: 441 GSDEYEDECP 450
             +  ED  P
Sbjct: 603 EEESGEDTGP 612


>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
          Length = 671

 Score = 33.5 bits (75), Expect = 0.52
 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 8/68 (11%)

Query: 187 VMELING----YPLCQIHHVEDPASVYDEAMELIVKL---ANHGLIHGDFNEFNLILDES 239
           VME +NG    Y + Q+   ++P +V+  A E+ + L    + G+I+ D    N++LD  
Sbjct: 419 VMEYVNGGDLMYHIQQVGRFKEPHAVF-YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSE 477

Query: 240 DHITMIDF 247
            HI + DF
Sbjct: 478 GHIKIADF 485


>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
          Length = 673

 Score = 33.5 bits (75), Expect = 0.52
 Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 8/68 (11%)

Query: 187 VMELING----YPLCQIHHVEDPASVYDEAMELIVKL---ANHGLIHGDFNEFNLILDES 239
           VME +NG    Y + Q+   ++P +V+  A E+ + L    + G+I+ D    N++LD  
Sbjct: 419 VMEYVNGGDLMYHIQQVGRFKEPHAVF-YAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSE 477

Query: 240 DHITMIDF 247
            HI + DF
Sbjct: 478 GHIKIADF 485


>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
           [Homo sapiens]
          Length = 1828

 Score = 33.5 bits (75), Expect = 0.52
 Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 11/137 (8%)

Query: 380 SLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVP 439
           S SEE++ + S   +E  Q  +   G   E+NS +E SE ++ +E  +   G + Q  +P
Sbjct: 23  SASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESE--SESAGSKSQPVLP 80

Query: 440 AGSDEYEDECPHLIALSSLNREFRPFRDEENVGAMNQYRTR--TLSITSSGSAVSCSTIP 497
              ++   +      ++ + + +  + D   V   N+ R      +I    S+ S S  P
Sbjct: 81  EAKEKPASKKER---IADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSP 137

Query: 498 PELVKQKVKRQLTKQQK 514
               K++ +RQL KQ+K
Sbjct: 138 ----KRRGQRQLKKQEK 150


>gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2
           [Homo sapiens]
          Length = 501

 Score = 33.5 bits (75), Expect = 0.52
 Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 11/137 (8%)

Query: 380 SLSEESADARSFEMTEFNQALEEIKGQVVENNSVTEFSEEKNRTENYNRQDGQRVQGGVP 439
           S SEE++ + S   +E  Q  +   G   E+NS +E SE ++ +E  +   G + Q  +P
Sbjct: 23  SASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQSESE--SESAGSKSQPVLP 80

Query: 440 AGSDEYEDECPHLIALSSLNREFRPFRDEENVGAMNQYRTR--TLSITSSGSAVSCSTIP 497
              ++   +      ++ + + +  + D   V   N+ R      +I    S+ S S  P
Sbjct: 81  EAKEKPASKKER---IADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSP 137

Query: 498 PELVKQKVKRQLTKQQK 514
               K++ +RQL KQ+K
Sbjct: 138 ----KRRGQRQLKKQEK 150


>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
           sapiens]
          Length = 707

 Score = 33.1 bits (74), Expect = 0.68
 Identities = 30/130 (23%), Positives = 56/130 (43%), Gaps = 13/130 (10%)

Query: 301 SASGYTKEMQADDELLHPLGPDDKNIETKEGSE-FSFSDGEVAEKAEVYGSENESERNCL 359
           S  G     Q D+E ++ +  +++  + ++  E  +  +GEV       G +N+S++  L
Sbjct: 18  SLRGNPSSSQVDEEQMNRVVEEEQQQQLRQQEEEHTARNGEVVGVEPRPGGQNDSQQGQL 77

Query: 360 EESEGCYCR----SSGDPEQIKEDSLSEESADARSFEMTEFNQALEEI--------KGQV 407
           EE+   +      SSG+ E+ +ED       D    E  E +Q  ++         + + 
Sbjct: 78  EENNNRFISVDEDSSGNQEEQEEDEEHAGEQDEEDEEEEEMDQESDDFDQSDDSSREDEH 137

Query: 408 VENNSVTEFS 417
              NSVT  S
Sbjct: 138 THTNSVTNSS 147


>gi|4506067 protein kinase C, alpha [Homo sapiens]
          Length = 672

 Score = 32.7 bits (73), Expect = 0.89
 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 8/68 (11%)

Query: 187 VMELING----YPLCQIHHVEDPASVYDEAMELIVKLA---NHGLIHGDFNEFNLILDES 239
           VME +NG    Y + Q+   ++P +V+  A E+ + L      G+I+ D    N++LD  
Sbjct: 416 VMEYVNGGDLMYHIQQVGKFKEPQAVF-YAAEISIGLFFLHKRGIIYRDLKLDNVMLDSE 474

Query: 240 DHITMIDF 247
            HI + DF
Sbjct: 475 GHIKIADF 482


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,762,888
Number of Sequences: 37866
Number of extensions: 860175
Number of successful extensions: 3380
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 3197
Number of HSP's gapped (non-prelim): 253
length of query: 552
length of database: 18,247,518
effective HSP length: 107
effective length of query: 445
effective length of database: 14,195,856
effective search space: 6317155920
effective search space used: 6317155920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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