BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|229094128 active breakpoint cluster region-related protein isoform c [Homo sapiens] (813 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|229094128 active breakpoint cluster region-related protein i... 1617 0.0 gi|38679957 active breakpoint cluster region-related protein is... 1617 0.0 gi|38679954 active breakpoint cluster region-related protein is... 1543 0.0 gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 1134 0.0 gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 1043 0.0 gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 137 3e-32 gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 137 3e-32 gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo sa... 135 2e-31 gi|188497642 ARHGAP15 [Homo sapiens] 129 1e-29 gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 126 7e-29 gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 126 7e-29 gi|239746665 PREDICTED: hypothetical protein XP_002343826 [Homo ... 120 5e-27 gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 120 5e-27 gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 119 1e-26 gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 117 6e-26 gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap... 116 7e-26 gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap... 116 7e-26 gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 115 2e-25 gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 115 2e-25 gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 115 2e-25 gi|4757980 beta chimerin isoform 2 [Homo sapiens] 113 8e-25 gi|91106928 beta chimerin isoform 1 [Homo sapiens] 113 8e-25 gi|239757684 PREDICTED: hypothetical protein [Homo sapiens] 112 1e-24 gi|239752174 PREDICTED: hypothetical protein XP_002348160 [Homo ... 112 1e-24 gi|239746697 PREDICTED: hypothetical protein XP_002343833 [Homo ... 112 1e-24 gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 112 2e-24 gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 111 2e-24 gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 111 3e-24 gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Hom... 109 9e-24 gi|23510413 sorting nexin 26 [Homo sapiens] 109 9e-24 >gi|229094128 active breakpoint cluster region-related protein isoform c [Homo sapiens] Length = 813 Score = 1617 bits (4186), Expect = 0.0 Identities = 813/813 (100%), Positives = 813/813 (100%) Query: 1 MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 60 MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY Sbjct: 1 MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 60 Query: 61 INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 120 INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS Sbjct: 61 INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 120 Query: 121 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 180 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS Sbjct: 121 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 180 Query: 181 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 240 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID Sbjct: 181 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 240 Query: 241 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 300 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC Sbjct: 241 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 300 Query: 301 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 360 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER Sbjct: 301 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 360 Query: 361 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 420 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV Sbjct: 361 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 420 Query: 421 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 480 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL Sbjct: 421 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 480 Query: 481 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 540 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI Sbjct: 481 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 540 Query: 541 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 600 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG Sbjct: 541 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 600 Query: 601 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 660 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL Sbjct: 601 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 660 Query: 661 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 720 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD Sbjct: 661 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 720 Query: 721 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 780 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD Sbjct: 721 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 780 Query: 781 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV Sbjct: 781 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813 >gi|38679957 active breakpoint cluster region-related protein isoform a [Homo sapiens] Length = 859 Score = 1617 bits (4186), Expect = 0.0 Identities = 813/813 (100%), Positives = 813/813 (100%) Query: 1 MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 60 MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY Sbjct: 47 MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 106 Query: 61 INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 120 INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS Sbjct: 107 INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 166 Query: 121 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 180 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS Sbjct: 167 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 226 Query: 181 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 240 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID Sbjct: 227 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 286 Query: 241 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 300 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC Sbjct: 287 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 346 Query: 301 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 360 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER Sbjct: 347 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 406 Query: 361 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 420 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV Sbjct: 407 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 466 Query: 421 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 480 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL Sbjct: 467 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 526 Query: 481 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 540 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI Sbjct: 527 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 586 Query: 541 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 600 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG Sbjct: 587 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 646 Query: 601 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 660 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL Sbjct: 647 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 706 Query: 661 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 720 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD Sbjct: 707 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 766 Query: 721 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 780 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD Sbjct: 767 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 826 Query: 781 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV Sbjct: 827 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 859 >gi|38679954 active breakpoint cluster region-related protein isoform b [Homo sapiens] Length = 822 Score = 1543 bits (3996), Expect = 0.0 Identities = 781/793 (98%), Positives = 783/793 (98%), Gaps = 5/793 (0%) Query: 26 SPTPPEGLAP-----GVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATT 80 +PT P +P VEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATT Sbjct: 30 TPTSPGSGSPFLVAVKVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATT 89 Query: 81 SQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKA 140 SQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKA Sbjct: 90 SQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKA 149 Query: 141 FVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRS 200 FVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRS Sbjct: 150 FVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRS 209 Query: 201 TLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDG 260 TLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDG Sbjct: 210 TLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDG 269 Query: 261 FLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEAS 320 FLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEAS Sbjct: 270 FLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEAS 329 Query: 321 PQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIP 380 PQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIP Sbjct: 330 PQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIP 389 Query: 381 FRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVH 440 FRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVH Sbjct: 390 FRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVH 449 Query: 441 NIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDT 500 NIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDT Sbjct: 450 NIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDT 509 Query: 501 AEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETK 560 AEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETK Sbjct: 510 AEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETK 569 Query: 561 NWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQ 620 NWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQ Sbjct: 570 NWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQ 629 Query: 621 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR 680 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR Sbjct: 630 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR 689 Query: 681 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE 740 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE Sbjct: 690 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE 749 Query: 741 PINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 800 PINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA Sbjct: 750 PINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 809 Query: 801 ELKRNTLYFSTDV 813 ELKRNTLYFSTDV Sbjct: 810 ELKRNTLYFSTDV 822 >gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] Length = 1271 Score = 1134 bits (2933), Expect = 0.0 Identities = 569/820 (69%), Positives = 679/820 (82%), Gaps = 8/820 (0%) Query: 1 MPYIDESPTMSPQLSARSQGGGDG-VSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEI 59 +PYID+SP+ SP LS++ +G D VS A ++ KGLEMRK VLSG LASEE Sbjct: 453 LPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEET 512 Query: 60 YINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWD 119 Y++ LEALLLPMKPLKA ATTSQPVLT QQIETIF+K+ ++YEIHKEFYD L P+VQQW Sbjct: 513 YLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWS 572 Query: 120 SQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKD 179 Q +G LFQKLASQLGVY+AFVDNY VA+E AEKC Q+N QF +ISE L+ + KD+KD Sbjct: 573 HQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKD 632 Query: 180 SHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDI 239 T ++E LLYKP+DRVTRSTLVLHDLLKHTP HPD+PLLQDALRISQNFLSSINE+I Sbjct: 633 PTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEI 692 Query: 240 DPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYD 299 PRR ++T KGE RQL+KD F+VE+ E +RKLRHVFLFTD+LLC KLKK S GK QQYD Sbjct: 693 TPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYD 752 Query: 300 CKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEK-ANKGQSRAI 358 CKWYIPL DL F +E EA P + PD EL+ +K+KIS +K++IQ+EK ANKG S+A Sbjct: 753 CKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKG-SKAT 811 Query: 359 ERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQA 418 ERLKKK+ E E LLLL SP++ FR+H+RNGKSY FL+SSDYER+EWRE I++ QKK ++ Sbjct: 812 ERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRS 871 Query: 419 FVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYC 478 F L+SVELQ+LT SC KL+TVH+IP+T NK+DDESPGLYGFL+VIVHSA GFKQS+NLYC Sbjct: 872 FSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYC 931 Query: 479 TLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNN 538 TLEVDSFGYFV+KAKTRV+RDTAEP W+EEFEIELEGSQ+LRILCYEKCY+KTK+ K++ Sbjct: 932 TLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKEDG 991 Query: 539 EIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGV 598 E D++MGKGQ+QLDPQ ++ ++W VI MNGI+V+ S+KF SR+ SLKR PS+KQTGV Sbjct: 992 ESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGV 1051 Query: 599 FGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKD 658 FGVKI+VVTKRERSKVPYIVRQCVEE+E+RG+EEVGIYR+SGVATDIQALKA FD NNKD Sbjct: 1052 FGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKD 1111 Query: 659 ILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSL 718 + +M+S+MD+NAIAGTLKLYFRELPEPL TD YP F EGIALSDP AKE+CM++LL SL Sbjct: 1112 VSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSL 1171 Query: 719 PDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESK-----AHLTSA 773 P+ NL+TFLFLL+HLKRVAEKE +NKMSLHNLATVFGPTLLRPSE ESK + + Sbjct: 1172 PEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITM 1231 Query: 774 ADIWSHDVMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813 D WS +VM+QVQVLLY+LQ I + KR ++ FST+V Sbjct: 1232 TDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV 1271 >gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] Length = 1227 Score = 1043 bits (2696), Expect = 0.0 Identities = 537/820 (65%), Positives = 639/820 (77%), Gaps = 52/820 (6%) Query: 1 MPYIDESPTMSPQLSARSQGGGDG-VSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEI 59 +PYID+SP+ SP LS++ +G D VS A ++ KGLEMRK VLSG LASEE Sbjct: 453 LPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEET 512 Query: 60 YINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWD 119 Y++ LEALLLPMKPLKA ATTSQPVLT QQIETIF+K+ ++YEIHKEFYD L P+VQQW Sbjct: 513 YLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWS 572 Query: 120 SQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKD 179 Q +G LFQKLASQLGVY+AFVDNY VA+E AEKC Q+N QF +ISE L+ + KD+KD Sbjct: 573 HQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKD 632 Query: 180 SHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDI 239 T ++E LLYKP+DRVTRSTLVLHDLLKHTP HPD+PLLQDALRISQNFLSSINE+I Sbjct: 633 PTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEI 692 Query: 240 DPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYD 299 PRR ++T KGE RQL+KD F+VE+ E +RKLRHVFLFTD+LLC KLKK S GK QQYD Sbjct: 693 TPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYD 752 Query: 300 CKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEK-ANKGQSRAI 358 CKWYIPL DL F +E EA P + PD EL+ +K+KIS +K++IQ+EK ANKG S+A Sbjct: 753 CKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKG-SKAT 811 Query: 359 ERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQA 418 ERLKKK+ E E LLLL SP++ FR+H+RNGKSY FL+SSDYER+EWRE I++ QKK ++ Sbjct: 812 ERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRS 871 Query: 419 FVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYC 478 F L+SVELQ+LT SC KL+TVH+IP+T NK+DDESPGLYGFL+VIVHSA GFKQS+NLYC Sbjct: 872 FSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYC 931 Query: 479 TLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNN 538 TLEVDSFGYFV+KAKTRV+RDTAEP W+E Sbjct: 932 TLEVDSFGYFVNKAKTRVYRDTAEPNWNE------------------------------- 960 Query: 539 EIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGV 598 LDPQ ++ ++W VI MNGI+V+ S+KF SR+ SLKR PS+KQTGV Sbjct: 961 -------------LDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGV 1007 Query: 599 FGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKD 658 FGVKI+VVTKRERSKVPYIVRQCVEE+E+RG+EEVGIYR+SGVATDIQALKA FD NNKD Sbjct: 1008 FGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKD 1067 Query: 659 ILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSL 718 + +M+S+MD+NAIAGTLKLYFRELPEPL TD YP F EGIALSDP AKE+CM++LL SL Sbjct: 1068 VSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSL 1127 Query: 719 PDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESK-----AHLTSA 773 P+ NL+TFLFLL+HLKRVAEKE +NKMSLHNLATVFGPTLLRPSE ESK + + Sbjct: 1128 PEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITM 1187 Query: 774 ADIWSHDVMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813 D WS +VM+QVQVLLY+LQ I + KR ++ FST+V Sbjct: 1188 TDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV 1227 >gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sapiens] Length = 521 Score = 137 bits (346), Expect = 3e-32 Identities = 83/198 (41%), Positives = 114/198 (57%), Gaps = 8/198 (4%) Query: 579 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 636 KF R +L+ K + VFG ++ + +RERS+VP V+QC+ VE RG++ G+Y Sbjct: 305 KFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLY 364 Query: 637 RISGVATDIQALKAVFDANNKDILLMLSD---MDINAIAGTLKLYFRELPEPLLTDRLYP 693 RISG IQ L+ D + + L L D D++ I G LKL+FRELPEPL + Sbjct: 365 RISGNLATIQKLRYKVDHDER---LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFR 421 Query: 694 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 753 F+ I L D A + C+ L+RSLP PN T L +HL RV E N+MS+ ++A V Sbjct: 422 QFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIV 481 Query: 754 FGPTLLRPSEVESKAHLT 771 FGPTLLRP E+ +T Sbjct: 482 FGPTLLRPEVEETSMPMT 499 >gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sapiens] Length = 548 Score = 137 bits (346), Expect = 3e-32 Identities = 83/198 (41%), Positives = 114/198 (57%), Gaps = 8/198 (4%) Query: 579 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 636 KF R +L+ K + VFG ++ + +RERS+VP V+QC+ VE RG++ G+Y Sbjct: 332 KFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLY 391 Query: 637 RISGVATDIQALKAVFDANNKDILLMLSD---MDINAIAGTLKLYFRELPEPLLTDRLYP 693 RISG IQ L+ D + + L L D D++ I G LKL+FRELPEPL + Sbjct: 392 RISGNLATIQKLRYKVDHDER---LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFR 448 Query: 694 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 753 F+ I L D A + C+ L+RSLP PN T L +HL RV E N+MS+ ++A V Sbjct: 449 QFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIV 508 Query: 754 FGPTLLRPSEVESKAHLT 771 FGPTLLRP E+ +T Sbjct: 509 FGPTLLRPEVEETSMPMT 526 >gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo sapiens] Length = 1194 Score = 135 bits (340), Expect = 2e-31 Identities = 111/372 (29%), Positives = 177/372 (47%), Gaps = 36/372 (9%) Query: 458 GFLHVIVHSAKGFK----QSANLYCTLEVDSFGYFVSKAKTRVFR-DTAEPKWDEEFEIE 512 G + V + A+ K S +++C ++VDS V+KA+T + T D F IE Sbjct: 680 GLMSVHFYGAEDLKPPRIDSKDVFCAIQVDS----VNKARTALLTCRTTFLDMDHTFNIE 735 Query: 513 LEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDV-IEMNG 571 +E +Q L+++ + ++ T +++ G + L TK V +E G Sbjct: 736 IENAQHLKLVVFS--WEPTPRK-------NRVCCHGTVVLPTLFRVTKTHQLAVKLEPRG 786 Query: 572 IKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERS--KVPYIVRQCVEEVEKRG 629 + + SL ++ +FGV I V ++E VP ++++C+ E+EKRG Sbjct: 787 LIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRG 846 Query: 630 IEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLT 688 + VG+YR+ G A + L+ F+ ++K + L + DIN I G LK Y RELP PL+T Sbjct: 847 CQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLIT 906 Query: 689 DRLYPAFMEGIALSDPAAKEN----------CMMHLLRSLPDPNLITFLFLLEHLKRVAE 738 +LY A ++ +A S N + LL LP+ T LL+HLK VA Sbjct: 907 KQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVAS 966 Query: 739 KEPINKMSLHNLATVFGPTLL----RPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 794 +NKM+ NLA FGP LL PS ++ S + D ++VL Y LQ Sbjct: 967 YHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQL 1026 Query: 795 PPISFAELKRNT 806 P+ +K++T Sbjct: 1027 WPVQRLTVKKST 1038 >gi|188497642 ARHGAP15 [Homo sapiens] Length = 475 Score = 129 bits (324), Expect = 1e-29 Identities = 79/202 (39%), Positives = 109/202 (53%), Gaps = 9/202 (4%) Query: 564 TDVIEMNGIKVEFSMKFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQC 621 +D + N +K KF +R SLK K + +FG + V +RE S VP+ V+QC Sbjct: 243 SDTSDKNRVKSRLK-KFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQC 301 Query: 622 VEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM---DINAIAGTLKLY 678 +E VEKRG++ GIYR+SG IQ L+ + + K L L D DI+ + G LK++ Sbjct: 302 IEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEK---LNLDDSQWEDIHVVTGALKMF 358 Query: 679 FRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAE 738 FRELPEPL + F+E I D + + L++ LP PN T L HL ++ Sbjct: 359 FRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVA 418 Query: 739 KEPINKMSLHNLATVFGPTLLR 760 K N MS +L VFGPTLLR Sbjct: 419 KASKNLMSTQSLGIVFGPTLLR 440 >gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] Length = 459 Score = 126 bits (317), Expect = 7e-29 Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%) Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657 V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + + Sbjct: 265 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 324 Query: 658 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 715 DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L Sbjct: 325 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383 Query: 716 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 770 + LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L Sbjct: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 438 >gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] Length = 433 Score = 126 bits (317), Expect = 7e-29 Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%) Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657 V+ ++ + K +K P +V C+ E+E RG+ G+YR+SG + I+ +K FD + + Sbjct: 239 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 298 Query: 658 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 715 DI + + + DIN I G LKLYFR+LP PL+T YP F+E + DP + + L Sbjct: 299 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357 Query: 716 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 770 + LP + T +L+ HLKRV E N M+ NL VFGPTL+R E+++ A L Sbjct: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 412 >gi|239746665 PREDICTED: hypothetical protein XP_002343826 [Homo sapiens] Length = 181 Score = 120 bits (301), Expect = 5e-27 Identities = 63/105 (60%), Positives = 80/105 (76%), Gaps = 10/105 (9%) Query: 688 TDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSL 747 +D L PA ALSDP AK++CM++LL SLP+ NL+TFLFLL+HL+R+AEKE +NKMSL Sbjct: 32 SDPLPPA-----ALSDPVAKKSCMLNLLSSLPEANLLTFLFLLDHLERMAEKEAVNKMSL 86 Query: 748 HNLATVFGPTLLRPSEVESK-----AHLTSAADIWSHDVMAQVQV 787 HNL TVFGPTLLRPSE ESK + + D WS +VM+Q+Q+ Sbjct: 87 HNLGTVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQIQI 131 >gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] Length = 846 Score = 120 bits (301), Expect = 5e-27 Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%) Query: 579 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 636 KF +R +L+ K + VFG ++ + +RE VP V+ C+E VE+ G++ GIY Sbjct: 632 KFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIY 691 Query: 637 RISGVATDIQALKAVFDANNKDILLMLSDM---DINAIAGTLKLYFRELPEPLLTDRLYP 693 R+SG IQ L+ A N D L L+D DI+ I G LK++FRELPEPL T + Sbjct: 692 RVSGNLAVIQKLRF---AVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFN 748 Query: 694 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 753 F+ I +P + + L+R LP PN T L HL+RV E N+M+ ++A V Sbjct: 749 DFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIV 807 Query: 754 FGPTLLRPSE 763 FGPTLL+P + Sbjct: 808 FGPTLLKPEK 817 >gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sapiens] Length = 735 Score = 119 bits (297), Expect = 1e-26 Identities = 107/368 (29%), Positives = 169/368 (45%), Gaps = 57/368 (15%) Query: 456 LYGFLHVIVHSAKGFKQSA-----NLYCTLEVDSFGYFVSKAKTRVFRDTAE-PKWDEEF 509 L+G L + ++ G + + +L C L+VD ++A+T R + + D F Sbjct: 264 LWGRLSLHLYGLGGLRPAPGATPRDLCCLLQVDG----EARARTGPLRGGPDFLRLDHTF 319 Query: 510 EIELEGSQSLR--ILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQ-----LDPQTVETKNW 562 +ELE ++ LR +L ++ + + ++ + Q Q L+PQ + Sbjct: 320 HLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTVFRGCQAQQLAVRLEPQGL----- 374 Query: 563 HTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRER--SKVPYIVRQ 620 K T + + P+ + VFG+ + ++ +RER +VP I+++ Sbjct: 375 -------------LYAKLTLSEQ--QEAPATAEPRVFGLPLPLLVERERPPGQVPLIIQK 419 Query: 621 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM--DINAIAGTLKLY 678 CV ++E+RG+ VG+YR+ G A + L+ F+ ++ + L D+ DIN I G LK Y Sbjct: 420 CVGQIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLS-EDLYPDINVITGILKDY 478 Query: 679 FRELPEPLLTDRLYPAFMEGIALSDP---AAKENCMMHLLRSLPDPNLITFLFLLEHLKR 735 RELP PL+T LY +E +A P LL LPD T LL+HL+ Sbjct: 479 LRELPTPLITQPLYKVVLEAMARDPPNRVPPTTEGTRGLLSCLPDVERATLTLLLDHLRL 538 Query: 736 VAEKEPINKMSLHNLATVFGPTLL-------RPSEVESKAHLTSAADIWSHDVMAQVQVL 788 V+ N+M+ NLA FGP LL RP S L SA D H ++VL Sbjct: 539 VSSFHAYNRMTPQNLAVCFGPVLLPARQAPTRPRARSSGPGLASAVDFKHH-----IEVL 593 Query: 789 LYYLQHPP 796 Y LQ P Sbjct: 594 HYLLQSWP 601 >gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] Length = 1136 Score = 117 bits (292), Expect = 6e-26 Identities = 76/217 (35%), Positives = 112/217 (51%), Gaps = 27/217 (12%) Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657 +FG S + VP+IV++CV E+E+R + GIYR++GV T ++ L F+ N K Sbjct: 758 LFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFE-NGK 816 Query: 658 DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENC------- 710 + L+ LS + I+ LKLY R+LPEPL++ RLY + G+A A+ Sbjct: 817 E-LVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELV-GLAKDSLKAEAEAKAASRGR 874 Query: 711 ----------------MMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVF 754 + LLR LP N + +LL HL+R+ E E NKM+ NL VF Sbjct: 875 QDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVF 934 Query: 755 GPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYY 791 GPTLLRP E+ L+S D + H ++++Y Sbjct: 935 GPTLLRPRPTEATVSLSSLVD-YPHQARVIETLIVHY 970 >gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sapiens] Length = 890 Score = 116 bits (291), Expect = 7e-26 Identities = 74/214 (34%), Positives = 117/214 (54%), Gaps = 7/214 (3%) Query: 582 SRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGV 641 SR K+ +K++ VFG + + +VP +++ C E VE+ G+ + GIYR+SGV Sbjct: 3 SRQKGKKKGSAKER--VFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGV 59 Query: 642 ATDIQALKAVFDANNK-DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIA 700 +++IQ L+ F++ K D+ + DI+ ++ K YFRELP+PLLT RLY F E + Sbjct: 60 SSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVG 119 Query: 701 LSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLR 760 + + ++ +LR LP PN T FL+ HL +A M NLA V+ P LLR Sbjct: 120 VQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLR 179 Query: 761 PSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 794 ++E+ +AA + +V Q V+ + L H Sbjct: 180 SKDIEASGFNGTAAFM---EVRVQSIVVEFILTH 210 >gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sapiens] Length = 1101 Score = 116 bits (291), Expect = 7e-26 Identities = 74/214 (34%), Positives = 117/214 (54%), Gaps = 7/214 (3%) Query: 582 SRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGV 641 SR K+ +K++ VFG + + +VP +++ C E VE+ G+ + GIYR+SGV Sbjct: 3 SRQKGKKKGSAKER--VFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGV 59 Query: 642 ATDIQALKAVFDANNK-DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIA 700 +++IQ L+ F++ K D+ + DI+ ++ K YFRELP+PLLT RLY F E + Sbjct: 60 SSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVG 119 Query: 701 LSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLR 760 + + ++ +LR LP PN T FL+ HL +A M NLA V+ P LLR Sbjct: 120 VQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLR 179 Query: 761 PSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 794 ++E+ +AA + +V Q V+ + L H Sbjct: 180 SKDIEASGFNGTAAFM---EVRVQSIVVEFILTH 210 >gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sapiens] Length = 731 Score = 115 bits (288), Expect = 2e-25 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 18/187 (9%) Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 654 VFG ++ + +RE VP +R C+ V+KRG++ GIYR+SG +Q L+ + D A Sbjct: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579 Query: 655 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGI 699 D + + DI+ + G LKL+ RELP+PL+ L P F + Sbjct: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639 Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759 ALS+ + + L+ S+P PN T +LLEHL RV N+M+ HNL VFGPTL Sbjct: 640 ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699 Query: 760 RPSEVES 766 RP + S Sbjct: 700 RPEQETS 706 >gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sapiens] Length = 547 Score = 115 bits (288), Expect = 2e-25 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 18/187 (9%) Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 654 VFG ++ + +RE VP +R C+ V+KRG++ GIYR+SG +Q L+ + D A Sbjct: 336 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 395 Query: 655 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGI 699 D + + DI+ + G LKL+ RELP+PL+ L P F + Sbjct: 396 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 455 Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759 ALS+ + + L+ S+P PN T +LLEHL RV N+M+ HNL VFGPTL Sbjct: 456 ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 515 Query: 760 RPSEVES 766 RP + S Sbjct: 516 RPEQETS 522 >gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] Length = 1958 Score = 115 bits (287), Expect = 2e-25 Identities = 77/219 (35%), Positives = 111/219 (50%), Gaps = 12/219 (5%) Query: 587 LKRTPSKKQT--GVFGVKISVVTKRERSK-VPYIVRQCVEEVEKRGIEEVGIYRISGVAT 643 +++T KK T G FGV++ ++ +P IV C + VE+RG+E GIYR+ G Sbjct: 1131 MRKTFEKKPTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNA 1190 Query: 644 DIQALKAVFDANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALS 702 I +++ + DI + D+N I+ LK +FR+LPEPL T+ Y F+E Sbjct: 1191 AISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKE 1250 Query: 703 DPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPS 762 DP + + L+ LP+ + T FL HLK VAE NKM NLA VFGPTL+R S Sbjct: 1251 DPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTS 1310 Query: 763 EVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAE 801 E +T D Q +++ +QH F E Sbjct: 1311 EDNMTHMVTHMPD--------QYKIVETLIQHHDWFFTE 1341 >gi|4757980 beta chimerin isoform 2 [Homo sapiens] Length = 468 Score = 113 bits (282), Expect = 8e-25 Identities = 64/196 (32%), Positives = 107/196 (54%), Gaps = 4/196 (2%) Query: 593 KKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVF 652 K+ V+ ++ + K ++ P +V C+ E+E RG++ G+YR+SG I+ +K F Sbjct: 269 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF 328 Query: 653 DANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCM 711 D + + + + DIN I G LKLYFR+LP P++T Y F++ +S+ + + Sbjct: 329 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV 388 Query: 712 MHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLT 771 +L LP + T +L+ HLK+V E N M+ NL VFGPTL+RP E + LT Sbjct: 389 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE---DSTLT 445 Query: 772 SAADIWSHDVMAQVQV 787 + D+ ++ Q+ + Sbjct: 446 TLHDMRYQKLIVQILI 461 >gi|91106928 beta chimerin isoform 1 [Homo sapiens] Length = 332 Score = 113 bits (282), Expect = 8e-25 Identities = 64/196 (32%), Positives = 107/196 (54%), Gaps = 4/196 (2%) Query: 593 KKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVF 652 K+ V+ ++ + K ++ P +V C+ E+E RG++ G+YR+SG I+ +K F Sbjct: 133 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF 192 Query: 653 DANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCM 711 D + + + + DIN I G LKLYFR+LP P++T Y F++ +S+ + + Sbjct: 193 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV 252 Query: 712 MHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLT 771 +L LP + T +L+ HLK+V E N M+ NL VFGPTL+RP E + LT Sbjct: 253 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE---DSTLT 309 Query: 772 SAADIWSHDVMAQVQV 787 + D+ ++ Q+ + Sbjct: 310 TLHDMRYQKLIVQILI 325 >gi|239757684 PREDICTED: hypothetical protein [Homo sapiens] Length = 181 Score = 112 bits (281), Expect = 1e-24 Identities = 58/93 (62%), Positives = 74/93 (79%), Gaps = 5/93 (5%) Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759 ALSDP A+++CM++LL SLP+ NL+TFLFLL+ L+RVAEKE +NKMSLHNLATVFGPTLL Sbjct: 39 ALSDPVARKSCMLNLLLSLPEANLLTFLFLLDRLERVAEKEAVNKMSLHNLATVFGPTLL 98 Query: 760 RPSEVESK-----AHLTSAADIWSHDVMAQVQV 787 RPSE ESK + + D S +VM+Q+Q+ Sbjct: 99 RPSEKESKLPANPSQPITMTDSRSLEVMSQIQI 131 >gi|239752174 PREDICTED: hypothetical protein XP_002348160 [Homo sapiens] Length = 181 Score = 112 bits (281), Expect = 1e-24 Identities = 58/93 (62%), Positives = 74/93 (79%), Gaps = 5/93 (5%) Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759 ALSDP A+++CM++LL SLP+ NL+TFLFLL+ L+RVAEKE +NKMSLHNLATVFGPTLL Sbjct: 39 ALSDPVARKSCMLNLLLSLPEANLLTFLFLLDRLERVAEKEAVNKMSLHNLATVFGPTLL 98 Query: 760 RPSEVESK-----AHLTSAADIWSHDVMAQVQV 787 RPSE ESK + + D S +VM+Q+Q+ Sbjct: 99 RPSEKESKLPANPSQPITMTDSRSLEVMSQIQI 131 >gi|239746697 PREDICTED: hypothetical protein XP_002343833 [Homo sapiens] Length = 181 Score = 112 bits (281), Expect = 1e-24 Identities = 58/93 (62%), Positives = 74/93 (79%), Gaps = 5/93 (5%) Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759 ALSDP A+++CM++LL SLP+ NL+TFLFLL+ L+RVAEKE +NKMSLHNLATVFGPTLL Sbjct: 39 ALSDPVARKSCMLNLLLSLPEANLLTFLFLLDRLERVAEKEAVNKMSLHNLATVFGPTLL 98 Query: 760 RPSEVESK-----AHLTSAADIWSHDVMAQVQV 787 RPSE ESK + + D S +VM+Q+Q+ Sbjct: 99 RPSEKESKLPANPSQPITMTDSRSLEVMSQIQI 131 >gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] Length = 1397 Score = 112 bits (279), Expect = 2e-24 Identities = 67/167 (40%), Positives = 89/167 (53%), Gaps = 2/167 (1%) Query: 599 FGVKISVVTKR-ERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657 FGV++ E +VP IV C VE RG+E GIYR+ G + +L+ + Sbjct: 809 FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPG 868 Query: 658 DILLMLSD-MDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLR 716 DI L D+N I+ LK +FR+LPEPL TD Y F+E + D + + L+R Sbjct: 869 DINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIR 928 Query: 717 SLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSE 763 LP T FL+ HLK +A+ NKM NLA VFGPTL+R SE Sbjct: 929 DLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSE 975 >gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] Length = 2087 Score = 111 bits (278), Expect = 2e-24 Identities = 83/256 (32%), Positives = 132/256 (51%), Gaps = 20/256 (7%) Query: 554 PQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSK---KQTG-----VFGVKISV 605 PQ+V T + V + +G + F F +K P+K KQ G VFG + Sbjct: 324 PQSV-TNSVPKPVSKKHGKLITFLRTF------MKSRPTKQKLKQRGILKERVFGCDLGE 376 Query: 606 VTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANN-KDILLMLS 664 +VP +++ C +E+ GI + GIYR+SGVA++IQ L+ FD+ + D+ Sbjct: 377 HLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFDSEHVPDLTKEPY 435 Query: 665 DMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLI 724 DI+++ KLYFRELP PLLT +LY F + ++ + + + +++ LP P+ Sbjct: 436 VQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYR 495 Query: 725 TFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQ 784 T FL+ HL +A+ I M NLA V+ P LLR ++ES +AA + +V Q Sbjct: 496 TLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFM---EVRIQ 552 Query: 785 VQVLLYYLQHPPISFA 800 V+ + L H + F+ Sbjct: 553 SVVVEFILNHVDVLFS 568 >gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] Length = 1738 Score = 111 bits (277), Expect = 3e-24 Identities = 75/223 (33%), Positives = 119/223 (53%), Gaps = 13/223 (5%) Query: 587 LKRTPSK---KQTG-----VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRI 638 +K P+K KQ G VFG + +VP +++ C +E+ GI + GIYR+ Sbjct: 1 MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRL 59 Query: 639 SGVATDIQALKAVFDANN-KDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFME 697 SGVA++IQ L+ FD+ + D+ DI+++ KLYFRELP PLLT +LY F + Sbjct: 60 SGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSD 119 Query: 698 GIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPT 757 ++ + + + +++ LP P+ T FL+ HL +A+ I M NLA V+ P Sbjct: 120 AVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPN 179 Query: 758 LLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 800 LLR ++ES +AA + +V Q V+ + L H + F+ Sbjct: 180 LLRSKQIESACFSGTAAFM---EVRIQSVVVEFILNHVDVLFS 219 >gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Homo sapiens] Length = 2063 Score = 109 bits (273), Expect = 9e-24 Identities = 84/327 (25%), Positives = 146/327 (44%), Gaps = 58/327 (17%) Query: 29 PPEGLAPGVEAGKG--------LEMRKLVLSGFLASEEIYINQLEALLLP-MKPLKA--T 77 PPE P E ++MRK V L +E+ Y+ L L+ M+PLK Sbjct: 1042 PPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPEN 1101 Query: 78 ATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ--- 134 + P L ++ IF +I ++ E H++F + + +Q W +Q +G L + S+ Sbjct: 1102 SVLCDPSL----VDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVL 1157 Query: 135 LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPI 194 + +Y A++DN+ A + ++ F K E+ +++ + L+ KP+ Sbjct: 1158 VNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQ-------SMRENKEKQALSDLMIKPV 1210 Query: 195 DRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSIN----------------ED 238 R+ R L++ DLLKHTP DHPD+PLL +A R + IN ++ Sbjct: 1211 QRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQE 1270 Query: 239 IDPRRTAVTTPKGETRQLVKDGFLVEVSE-SSRKLRHVFLFTDVLLCAKLKKTSAGKHQ- 296 I+ + + R+ ++ ++EV +K R +FLFTD+++C LK+ S + Sbjct: 1271 IEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRS 1330 Query: 297 ---------------QYDCKWYIPLAD 308 +Y W +PL D Sbjct: 1331 SMSLYTAASVIDTASKYKMLWKLPLED 1357 >gi|23510413 sorting nexin 26 [Homo sapiens] Length = 1126 Score = 109 bits (273), Expect = 9e-24 Identities = 75/207 (36%), Positives = 112/207 (54%), Gaps = 9/207 (4%) Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657 VFG + VP ++R C E +E G+ + GIYR+SGV+++IQ L+ FD+ Sbjct: 312 VFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVD-GIYRLSGVSSNIQRLRHEFDSERI 370 Query: 658 DILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMM--HL 714 L + + DI++++ KLYFRELP PLLT +LY F E A+S P +E + + Sbjct: 371 PELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSE--AMSVPGEEERLVRVHDV 428 Query: 715 LRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAA 774 ++ LP P+ T +LL HL R+A M NLA V+ P LLR E+ES +AA Sbjct: 429 IQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAA 488 Query: 775 DIWSHDVMAQVQVLLYYLQHPPISFAE 801 +V Q V+ + L H + F++ Sbjct: 489 ---FREVRVQSVVVEFLLTHVDVLFSD 512 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,834,891 Number of Sequences: 37866 Number of extensions: 1318244 Number of successful extensions: 5146 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 145 Number of HSP's successfully gapped in prelim test: 72 Number of HSP's that attempted gapping in prelim test: 4717 Number of HSP's gapped (non-prelim): 296 length of query: 813 length of database: 18,247,518 effective HSP length: 111 effective length of query: 702 effective length of database: 14,044,392 effective search space: 9859163184 effective search space used: 9859163184 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.