Guide to the Human Genome
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Search of human proteins with 229094128

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|229094128 active breakpoint cluster region-related  protein
isoform c [Homo sapiens]
         (813 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|229094128 active breakpoint cluster region-related  protein i...  1617   0.0  
gi|38679957 active breakpoint cluster region-related  protein is...  1617   0.0  
gi|38679954 active breakpoint cluster region-related  protein is...  1543   0.0  
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]       1134   0.0  
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]       1043   0.0  
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa...   137   3e-32
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap...   137   3e-32
gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo sa...   135   2e-31
gi|188497642 ARHGAP15 [Homo sapiens]                                  129   1e-29
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]            126   7e-29
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]          126   7e-29
gi|239746665 PREDICTED: hypothetical protein XP_002343826 [Homo ...   120   5e-27
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]           120   5e-27
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap...   119   1e-26
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]      117   6e-26
gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo sap...   116   7e-26
gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo sap...   116   7e-26
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap...   115   2e-25
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap...   115   2e-25
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]          115   2e-25
gi|4757980 beta chimerin isoform 2 [Homo sapiens]                     113   8e-25
gi|91106928 beta chimerin isoform 1 [Homo sapiens]                    113   8e-25
gi|239757684 PREDICTED: hypothetical protein [Homo sapiens]           112   1e-24
gi|239752174 PREDICTED: hypothetical protein XP_002348160 [Homo ...   112   1e-24
gi|239746697 PREDICTED: hypothetical protein XP_002343833 [Homo ...   112   1e-24
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]          112   2e-24
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]   111   2e-24
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]    111   3e-24
gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Hom...   109   9e-24
gi|23510413 sorting nexin 26 [Homo sapiens]                           109   9e-24

>gi|229094128 active breakpoint cluster region-related  protein
           isoform c [Homo sapiens]
          Length = 813

 Score = 1617 bits (4186), Expect = 0.0
 Identities = 813/813 (100%), Positives = 813/813 (100%)

Query: 1   MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 60
           MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY
Sbjct: 1   MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 60

Query: 61  INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 120
           INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS
Sbjct: 61  INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 120

Query: 121 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 180
           QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS
Sbjct: 121 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 180

Query: 181 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 240
           HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID
Sbjct: 181 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 240

Query: 241 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 300
           PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC
Sbjct: 241 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 300

Query: 301 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 360
           KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER
Sbjct: 301 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 360

Query: 361 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 420
           LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV
Sbjct: 361 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 420

Query: 421 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 480
           LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL
Sbjct: 421 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 480

Query: 481 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 540
           EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI
Sbjct: 481 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 540

Query: 541 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 600
           VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG
Sbjct: 541 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 600

Query: 601 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 660
           VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL
Sbjct: 601 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 660

Query: 661 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 720
           LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD
Sbjct: 661 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 720

Query: 721 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 780
           PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD
Sbjct: 721 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 780

Query: 781 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813
           VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV
Sbjct: 781 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813


>gi|38679957 active breakpoint cluster region-related  protein
           isoform a [Homo sapiens]
          Length = 859

 Score = 1617 bits (4186), Expect = 0.0
 Identities = 813/813 (100%), Positives = 813/813 (100%)

Query: 1   MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 60
           MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY
Sbjct: 47  MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIY 106

Query: 61  INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 120
           INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS
Sbjct: 107 INQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDS 166

Query: 121 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 180
           QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS
Sbjct: 167 QVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS 226

Query: 181 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 240
           HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID
Sbjct: 227 HTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDID 286

Query: 241 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 300
           PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC
Sbjct: 287 PRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDC 346

Query: 301 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 360
           KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER
Sbjct: 347 KWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIER 406

Query: 361 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 420
           LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV
Sbjct: 407 LKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFV 466

Query: 421 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 480
           LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL
Sbjct: 467 LSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTL 526

Query: 481 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 540
           EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI
Sbjct: 527 EVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI 586

Query: 541 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 600
           VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG
Sbjct: 587 VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFG 646

Query: 601 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 660
           VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL
Sbjct: 647 VKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDIL 706

Query: 661 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 720
           LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD
Sbjct: 707 LMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPD 766

Query: 721 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 780
           PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD
Sbjct: 767 PNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHD 826

Query: 781 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813
           VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV
Sbjct: 827 VMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 859


>gi|38679954 active breakpoint cluster region-related  protein
           isoform b [Homo sapiens]
          Length = 822

 Score = 1543 bits (3996), Expect = 0.0
 Identities = 781/793 (98%), Positives = 783/793 (98%), Gaps = 5/793 (0%)

Query: 26  SPTPPEGLAP-----GVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATT 80
           +PT P   +P      VEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATT
Sbjct: 30  TPTSPGSGSPFLVAVKVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATT 89

Query: 81  SQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKA 140
           SQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKA
Sbjct: 90  SQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKA 149

Query: 141 FVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRS 200
           FVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRS
Sbjct: 150 FVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRS 209

Query: 201 TLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDG 260
           TLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDG
Sbjct: 210 TLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDIDPRRTAVTTPKGETRQLVKDG 269

Query: 261 FLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEAS 320
           FLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEAS
Sbjct: 270 FLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPSPEESEAS 329

Query: 321 PQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIP 380
           PQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIP
Sbjct: 330 PQVHPFPDHELEDMKMKISALKSEIQKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIP 389

Query: 381 FRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVH 440
           FRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVH
Sbjct: 390 FRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLTGSCFKLRTVH 449

Query: 441 NIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDT 500
           NIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDT
Sbjct: 450 NIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDT 509

Query: 501 AEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETK 560
           AEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETK
Sbjct: 510 AEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETK 569

Query: 561 NWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQ 620
           NWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQ
Sbjct: 570 NWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQ 629

Query: 621 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR 680
           CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR
Sbjct: 630 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDMDINAIAGTLKLYFR 689

Query: 681 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE 740
           ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE
Sbjct: 690 ELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKE 749

Query: 741 PINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 800
           PINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA
Sbjct: 750 PINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 809

Query: 801 ELKRNTLYFSTDV 813
           ELKRNTLYFSTDV
Sbjct: 810 ELKRNTLYFSTDV 822


>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
          Length = 1271

 Score = 1134 bits (2933), Expect = 0.0
 Identities = 569/820 (69%), Positives = 679/820 (82%), Gaps = 8/820 (0%)

Query: 1    MPYIDESPTMSPQLSARSQGGGDG-VSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEI 59
            +PYID+SP+ SP LS++ +G  D  VS       A  ++  KGLEMRK VLSG LASEE 
Sbjct: 453  LPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEET 512

Query: 60   YINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWD 119
            Y++ LEALLLPMKPLKA ATTSQPVLT QQIETIF+K+ ++YEIHKEFYD L P+VQQW 
Sbjct: 513  YLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWS 572

Query: 120  SQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKD 179
             Q  +G LFQKLASQLGVY+AFVDNY VA+E AEKC Q+N QF +ISE L+ +  KD+KD
Sbjct: 573  HQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKD 632

Query: 180  SHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDI 239
              T  ++E LLYKP+DRVTRSTLVLHDLLKHTP  HPD+PLLQDALRISQNFLSSINE+I
Sbjct: 633  PTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEI 692

Query: 240  DPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYD 299
             PRR ++T  KGE RQL+KD F+VE+ E +RKLRHVFLFTD+LLC KLKK S GK QQYD
Sbjct: 693  TPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYD 752

Query: 300  CKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEK-ANKGQSRAI 358
            CKWYIPL DL F   +E EA P +   PD EL+ +K+KIS +K++IQ+EK ANKG S+A 
Sbjct: 753  CKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKG-SKAT 811

Query: 359  ERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQA 418
            ERLKKK+ E E LLLL SP++ FR+H+RNGKSY FL+SSDYER+EWRE I++ QKK  ++
Sbjct: 812  ERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRS 871

Query: 419  FVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYC 478
            F L+SVELQ+LT SC KL+TVH+IP+T NK+DDESPGLYGFL+VIVHSA GFKQS+NLYC
Sbjct: 872  FSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYC 931

Query: 479  TLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNN 538
            TLEVDSFGYFV+KAKTRV+RDTAEP W+EEFEIELEGSQ+LRILCYEKCY+KTK+ K++ 
Sbjct: 932  TLEVDSFGYFVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKIPKEDG 991

Query: 539  EIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGV 598
            E  D++MGKGQ+QLDPQ ++ ++W   VI MNGI+V+ S+KF SR+ SLKR PS+KQTGV
Sbjct: 992  ESTDRLMGKGQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGV 1051

Query: 599  FGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKD 658
            FGVKI+VVTKRERSKVPYIVRQCVEE+E+RG+EEVGIYR+SGVATDIQALKA FD NNKD
Sbjct: 1052 FGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKD 1111

Query: 659  ILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSL 718
            + +M+S+MD+NAIAGTLKLYFRELPEPL TD  YP F EGIALSDP AKE+CM++LL SL
Sbjct: 1112 VSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSL 1171

Query: 719  PDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESK-----AHLTSA 773
            P+ NL+TFLFLL+HLKRVAEKE +NKMSLHNLATVFGPTLLRPSE ESK     +   + 
Sbjct: 1172 PEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITM 1231

Query: 774  ADIWSHDVMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813
             D WS +VM+QVQVLLY+LQ   I   + KR ++ FST+V
Sbjct: 1232 TDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV 1271


>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
          Length = 1227

 Score = 1043 bits (2696), Expect = 0.0
 Identities = 537/820 (65%), Positives = 639/820 (77%), Gaps = 52/820 (6%)

Query: 1    MPYIDESPTMSPQLSARSQGGGDG-VSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEI 59
            +PYID+SP+ SP LS++ +G  D  VS       A  ++  KGLEMRK VLSG LASEE 
Sbjct: 453  LPYIDDSPSSSPHLSSKGRGSRDALVSGALESTKASELDLEKGLEMRKWVLSGILASEET 512

Query: 60   YINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWD 119
            Y++ LEALLLPMKPLKA ATTSQPVLT QQIETIF+K+ ++YEIHKEFYD L P+VQQW 
Sbjct: 513  YLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWS 572

Query: 120  SQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKD 179
             Q  +G LFQKLASQLGVY+AFVDNY VA+E AEKC Q+N QF +ISE L+ +  KD+KD
Sbjct: 573  HQQRVGDLFQKLASQLGVYRAFVDNYGVAMEMAEKCCQANAQFAEISENLRARSNKDAKD 632

Query: 180  SHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSINEDI 239
              T  ++E LLYKP+DRVTRSTLVLHDLLKHTP  HPD+PLLQDALRISQNFLSSINE+I
Sbjct: 633  PTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPDHPLLQDALRISQNFLSSINEEI 692

Query: 240  DPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYD 299
             PRR ++T  KGE RQL+KD F+VE+ E +RKLRHVFLFTD+LLC KLKK S GK QQYD
Sbjct: 693  TPRRQSMTVKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYD 752

Query: 300  CKWYIPLADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEIQKEK-ANKGQSRAI 358
            CKWYIPL DL F   +E EA P +   PD EL+ +K+KIS +K++IQ+EK ANKG S+A 
Sbjct: 753  CKWYIPLTDLSFQMVDELEAVPNIPLVPDEELDALKIKISQIKNDIQREKRANKG-SKAT 811

Query: 359  ERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQA 418
            ERLKKK+ E E LLLL SP++ FR+H+RNGKSY FL+SSDYER+EWRE I++ QKK  ++
Sbjct: 812  ERLKKKLSEQESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFRS 871

Query: 419  FVLSSVELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKGFKQSANLYC 478
            F L+SVELQ+LT SC KL+TVH+IP+T NK+DDESPGLYGFL+VIVHSA GFKQS+NLYC
Sbjct: 872  FSLTSVELQMLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYC 931

Query: 479  TLEVDSFGYFVSKAKTRVFRDTAEPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNN 538
            TLEVDSFGYFV+KAKTRV+RDTAEP W+E                               
Sbjct: 932  TLEVDSFGYFVNKAKTRVYRDTAEPNWNE------------------------------- 960

Query: 539  EIVDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGV 598
                         LDPQ ++ ++W   VI MNGI+V+ S+KF SR+ SLKR PS+KQTGV
Sbjct: 961  -------------LDPQALQDRDWQRTVIAMNGIEVKLSVKFNSREFSLKRMPSRKQTGV 1007

Query: 599  FGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKD 658
            FGVKI+VVTKRERSKVPYIVRQCVEE+E+RG+EEVGIYR+SGVATDIQALKA FD NNKD
Sbjct: 1008 FGVKIAVVTKRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKD 1067

Query: 659  ILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSL 718
            + +M+S+MD+NAIAGTLKLYFRELPEPL TD  YP F EGIALSDP AKE+CM++LL SL
Sbjct: 1068 VSVMMSEMDVNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSL 1127

Query: 719  PDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESK-----AHLTSA 773
            P+ NL+TFLFLL+HLKRVAEKE +NKMSLHNLATVFGPTLLRPSE ESK     +   + 
Sbjct: 1128 PEANLLTFLFLLDHLKRVAEKEAVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPITM 1187

Query: 774  ADIWSHDVMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV 813
             D WS +VM+QVQVLLY+LQ   I   + KR ++ FST+V
Sbjct: 1188 TDSWSLEVMSQVQVLLYFLQLEAIPAPDSKRQSILFSTEV 1227


>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
           sapiens]
          Length = 521

 Score =  137 bits (346), Expect = 3e-32
 Identities = 83/198 (41%), Positives = 114/198 (57%), Gaps = 8/198 (4%)

Query: 579 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 636
           KF  R  +L+    K   +  VFG  ++ + +RERS+VP  V+QC+  VE RG++  G+Y
Sbjct: 305 KFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLY 364

Query: 637 RISGVATDIQALKAVFDANNKDILLMLSD---MDINAIAGTLKLYFRELPEPLLTDRLYP 693
           RISG    IQ L+   D + +   L L D    D++ I G LKL+FRELPEPL     + 
Sbjct: 365 RISGNLATIQKLRYKVDHDER---LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFR 421

Query: 694 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 753
            F+  I L D A +  C+  L+RSLP PN  T   L +HL RV E    N+MS+ ++A V
Sbjct: 422 QFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIV 481

Query: 754 FGPTLLRPSEVESKAHLT 771
           FGPTLLRP   E+   +T
Sbjct: 482 FGPTLLRPEVEETSMPMT 499


>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
           sapiens]
          Length = 548

 Score =  137 bits (346), Expect = 3e-32
 Identities = 83/198 (41%), Positives = 114/198 (57%), Gaps = 8/198 (4%)

Query: 579 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 636
           KF  R  +L+    K   +  VFG  ++ + +RERS+VP  V+QC+  VE RG++  G+Y
Sbjct: 332 KFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLY 391

Query: 637 RISGVATDIQALKAVFDANNKDILLMLSD---MDINAIAGTLKLYFRELPEPLLTDRLYP 693
           RISG    IQ L+   D + +   L L D    D++ I G LKL+FRELPEPL     + 
Sbjct: 392 RISGNLATIQKLRYKVDHDER---LDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFR 448

Query: 694 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 753
            F+  I L D A +  C+  L+RSLP PN  T   L +HL RV E    N+MS+ ++A V
Sbjct: 449 QFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIV 508

Query: 754 FGPTLLRPSEVESKAHLT 771
           FGPTLLRP   E+   +T
Sbjct: 509 FGPTLLRPEVEETSMPMT 526


>gi|149274655 synapse defective 1, Rho GTPase, homolog 2 [Homo
            sapiens]
          Length = 1194

 Score =  135 bits (340), Expect = 2e-31
 Identities = 111/372 (29%), Positives = 177/372 (47%), Gaps = 36/372 (9%)

Query: 458  GFLHVIVHSAKGFK----QSANLYCTLEVDSFGYFVSKAKTRVFR-DTAEPKWDEEFEIE 512
            G + V  + A+  K     S +++C ++VDS    V+KA+T +    T     D  F IE
Sbjct: 680  GLMSVHFYGAEDLKPPRIDSKDVFCAIQVDS----VNKARTALLTCRTTFLDMDHTFNIE 735

Query: 513  LEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQLDPQTVETKNWHTDV-IEMNG 571
            +E +Q L+++ +   ++ T          +++   G + L      TK     V +E  G
Sbjct: 736  IENAQHLKLVVFS--WEPTPRK-------NRVCCHGTVVLPTLFRVTKTHQLAVKLEPRG 786

Query: 572  IKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRERS--KVPYIVRQCVEEVEKRG 629
            +           + SL      ++  +FGV I  V ++E     VP ++++C+ E+EKRG
Sbjct: 787  LIYVKVTLMEQWENSLHGLDINQEPIIFGVDIQKVVEKENIGLMVPLLIQKCIMEIEKRG 846

Query: 630  IEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLT 688
             + VG+YR+ G A   + L+  F+ ++K + L  +   DIN I G LK Y RELP PL+T
Sbjct: 847  CQVVGLYRLCGSAAVKKELREAFERDSKAVGLCENQYPDINVITGVLKDYLRELPSPLIT 906

Query: 689  DRLYPAFMEGIALSDPAAKEN----------CMMHLLRSLPDPNLITFLFLLEHLKRVAE 738
             +LY A ++ +A S      N            + LL  LP+    T   LL+HLK VA 
Sbjct: 907  KQLYEAVLDAMAKSPLKMSSNGCENDPGDSKYTVDLLDCLPEIEKATLKMLLDHLKLVAS 966

Query: 739  KEPINKMSLHNLATVFGPTLL----RPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 794
               +NKM+  NLA  FGP LL     PS   ++    S     + D    ++VL Y LQ 
Sbjct: 967  YHEVNKMTCQNLAVCFGPVLLSQRQEPSTHNNRVFTDSEELASALDFKKHIEVLHYLLQL 1026

Query: 795  PPISFAELKRNT 806
             P+    +K++T
Sbjct: 1027 WPVQRLTVKKST 1038


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score =  129 bits (324), Expect = 1e-29
 Identities = 79/202 (39%), Positives = 109/202 (53%), Gaps = 9/202 (4%)

Query: 564 TDVIEMNGIKVEFSMKFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQC 621
           +D  + N +K     KF +R  SLK    K   +  +FG  +  V +RE S VP+ V+QC
Sbjct: 243 SDTSDKNRVKSRLK-KFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQC 301

Query: 622 VEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM---DINAIAGTLKLY 678
           +E VEKRG++  GIYR+SG    IQ L+ + +   K   L L D    DI+ + G LK++
Sbjct: 302 IEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEK---LNLDDSQWEDIHVVTGALKMF 358

Query: 679 FRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAE 738
           FRELPEPL     +  F+E I   D   +   +  L++ LP PN  T   L  HL ++  
Sbjct: 359 FRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVA 418

Query: 739 KEPINKMSLHNLATVFGPTLLR 760
           K   N MS  +L  VFGPTLLR
Sbjct: 419 KASKNLMSTQSLGIVFGPTLLR 440


>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
          Length = 459

 Score =  126 bits (317), Expect = 7e-29
 Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)

Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657
           V+   ++ + K   +K P +V  C+ E+E RG+   G+YR+SG +  I+ +K  FD + +
Sbjct: 265 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 324

Query: 658 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 715
             DI + + + DIN I G LKLYFR+LP PL+T   YP F+E   + DP  +   +   L
Sbjct: 325 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 383

Query: 716 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 770
           + LP  +  T  +L+ HLKRV   E  N M+  NL  VFGPTL+R  E+++ A L
Sbjct: 384 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 438


>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
          Length = 433

 Score =  126 bits (317), Expect = 7e-29
 Identities = 68/175 (38%), Positives = 102/175 (58%), Gaps = 3/175 (1%)

Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657
           V+   ++ + K   +K P +V  C+ E+E RG+   G+YR+SG +  I+ +K  FD + +
Sbjct: 239 VYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGE 298

Query: 658 --DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLL 715
             DI + + + DIN I G LKLYFR+LP PL+T   YP F+E   + DP  +   +   L
Sbjct: 299 KADISVNMYE-DINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEAL 357

Query: 716 RSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHL 770
           + LP  +  T  +L+ HLKRV   E  N M+  NL  VFGPTL+R  E+++ A L
Sbjct: 358 KLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAAL 412


>gi|239746665 PREDICTED: hypothetical protein XP_002343826 [Homo
           sapiens]
          Length = 181

 Score =  120 bits (301), Expect = 5e-27
 Identities = 63/105 (60%), Positives = 80/105 (76%), Gaps = 10/105 (9%)

Query: 688 TDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSL 747
           +D L PA     ALSDP AK++CM++LL SLP+ NL+TFLFLL+HL+R+AEKE +NKMSL
Sbjct: 32  SDPLPPA-----ALSDPVAKKSCMLNLLSSLPEANLLTFLFLLDHLERMAEKEAVNKMSL 86

Query: 748 HNLATVFGPTLLRPSEVESK-----AHLTSAADIWSHDVMAQVQV 787
           HNL TVFGPTLLRPSE ESK     +   +  D WS +VM+Q+Q+
Sbjct: 87  HNLGTVFGPTLLRPSEKESKLPANPSQPITMTDSWSLEVMSQIQI 131


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score =  120 bits (301), Expect = 5e-27
 Identities = 75/190 (39%), Positives = 107/190 (56%), Gaps = 9/190 (4%)

Query: 579 KFTSRDMSLKRTPSKK--QTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIY 636
           KF +R  +L+    K   +  VFG  ++ + +RE   VP  V+ C+E VE+ G++  GIY
Sbjct: 632 KFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIY 691

Query: 637 RISGVATDIQALKAVFDANNKDILLMLSDM---DINAIAGTLKLYFRELPEPLLTDRLYP 693
           R+SG    IQ L+    A N D  L L+D    DI+ I G LK++FRELPEPL T   + 
Sbjct: 692 RVSGNLAVIQKLRF---AVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFN 748

Query: 694 AFMEGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATV 753
            F+  I   +P  +   +  L+R LP PN  T   L  HL+RV E    N+M+  ++A V
Sbjct: 749 DFVNAIK-QEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIV 807

Query: 754 FGPTLLRPSE 763
           FGPTLL+P +
Sbjct: 808 FGPTLLKPEK 817


>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
           sapiens]
          Length = 735

 Score =  119 bits (297), Expect = 1e-26
 Identities = 107/368 (29%), Positives = 169/368 (45%), Gaps = 57/368 (15%)

Query: 456 LYGFLHVIVHSAKGFKQSA-----NLYCTLEVDSFGYFVSKAKTRVFRDTAE-PKWDEEF 509
           L+G L + ++   G + +      +L C L+VD      ++A+T   R   +  + D  F
Sbjct: 264 LWGRLSLHLYGLGGLRPAPGATPRDLCCLLQVDG----EARARTGPLRGGPDFLRLDHTF 319

Query: 510 EIELEGSQSLR--ILCYEKCYDKTKVNKDNNEIVDKIMGKGQIQ-----LDPQTVETKNW 562
            +ELE ++ LR  +L ++    + +       ++  +    Q Q     L+PQ +     
Sbjct: 320 HLELEAARLLRALVLAWDPGVRRHRPCAQGTVLLPTVFRGCQAQQLAVRLEPQGL----- 374

Query: 563 HTDVIEMNGIKVEFSMKFTSRDMSLKRTPSKKQTGVFGVKISVVTKRER--SKVPYIVRQ 620
                           K T  +   +  P+  +  VFG+ + ++ +RER   +VP I+++
Sbjct: 375 -------------LYAKLTLSEQ--QEAPATAEPRVFGLPLPLLVERERPPGQVPLIIQK 419

Query: 621 CVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLSDM--DINAIAGTLKLY 678
           CV ++E+RG+  VG+YR+ G A   + L+  F+ ++  + L   D+  DIN I G LK Y
Sbjct: 420 CVGQIERRGLRVVGLYRLCGSAAVKKELRDAFERDSAAVCLS-EDLYPDINVITGILKDY 478

Query: 679 FRELPEPLLTDRLYPAFMEGIALSDP---AAKENCMMHLLRSLPDPNLITFLFLLEHLKR 735
            RELP PL+T  LY   +E +A   P            LL  LPD    T   LL+HL+ 
Sbjct: 479 LRELPTPLITQPLYKVVLEAMARDPPNRVPPTTEGTRGLLSCLPDVERATLTLLLDHLRL 538

Query: 736 VAEKEPINKMSLHNLATVFGPTLL-------RPSEVESKAHLTSAADIWSHDVMAQVQVL 788
           V+     N+M+  NLA  FGP LL       RP    S   L SA D   H     ++VL
Sbjct: 539 VSSFHAYNRMTPQNLAVCFGPVLLPARQAPTRPRARSSGPGLASAVDFKHH-----IEVL 593

Query: 789 LYYLQHPP 796
            Y LQ  P
Sbjct: 594 HYLLQSWP 601


>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
          Length = 1136

 Score =  117 bits (292), Expect = 6e-26
 Identities = 76/217 (35%), Positives = 112/217 (51%), Gaps = 27/217 (12%)

Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657
           +FG   S   +     VP+IV++CV E+E+R +   GIYR++GV T ++ L   F+ N K
Sbjct: 758 LFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFE-NGK 816

Query: 658 DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENC------- 710
           + L+ LS    + I+  LKLY R+LPEPL++ RLY   + G+A     A+          
Sbjct: 817 E-LVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELV-GLAKDSLKAEAEAKAASRGR 874

Query: 711 ----------------MMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVF 754
                           +  LLR LP  N  +  +LL HL+R+ E E  NKM+  NL  VF
Sbjct: 875 QDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVF 934

Query: 755 GPTLLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYY 791
           GPTLLRP   E+   L+S  D + H       ++++Y
Sbjct: 935 GPTLLRPRPTEATVSLSSLVD-YPHQARVIETLIVHY 970


>gi|71040096 Rho GTPase activating protein 30 isoform 2 [Homo
           sapiens]
          Length = 890

 Score =  116 bits (291), Expect = 7e-26
 Identities = 74/214 (34%), Positives = 117/214 (54%), Gaps = 7/214 (3%)

Query: 582 SRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGV 641
           SR    K+  +K++  VFG  +    +    +VP +++ C E VE+ G+ + GIYR+SGV
Sbjct: 3   SRQKGKKKGSAKER--VFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGV 59

Query: 642 ATDIQALKAVFDANNK-DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIA 700
           +++IQ L+  F++  K D+   +   DI+ ++   K YFRELP+PLLT RLY  F E + 
Sbjct: 60  SSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVG 119

Query: 701 LSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLR 760
           +     +   ++ +LR LP PN  T  FL+ HL  +A       M   NLA V+ P LLR
Sbjct: 120 VQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLR 179

Query: 761 PSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 794
             ++E+     +AA +   +V  Q  V+ + L H
Sbjct: 180 SKDIEASGFNGTAAFM---EVRVQSIVVEFILTH 210


>gi|71040098 Rho GTPase activating protein 30 isoform 1 [Homo
           sapiens]
          Length = 1101

 Score =  116 bits (291), Expect = 7e-26
 Identities = 74/214 (34%), Positives = 117/214 (54%), Gaps = 7/214 (3%)

Query: 582 SRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGV 641
           SR    K+  +K++  VFG  +    +    +VP +++ C E VE+ G+ + GIYR+SGV
Sbjct: 3   SRQKGKKKGSAKER--VFGCDLQEHLQHSGQEVPQVLKSCAEFVEEYGVVD-GIYRLSGV 59

Query: 642 ATDIQALKAVFDANNK-DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIA 700
           +++IQ L+  F++  K D+   +   DI+ ++   K YFRELP+PLLT RLY  F E + 
Sbjct: 60  SSNIQKLRQEFESERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVG 119

Query: 701 LSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLR 760
           +     +   ++ +LR LP PN  T  FL+ HL  +A       M   NLA V+ P LLR
Sbjct: 120 VQLEPERLVKILEVLRELPVPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLR 179

Query: 761 PSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQH 794
             ++E+     +AA +   +V  Q  V+ + L H
Sbjct: 180 SKDIEASGFNGTAAFM---EVRVQSIVVEFILTH 210


>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
           sapiens]
          Length = 731

 Score =  115 bits (288), Expect = 2e-25
 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 18/187 (9%)

Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 654
           VFG ++  + +RE   VP  +R C+  V+KRG++  GIYR+SG    +Q L+ + D   A
Sbjct: 520 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 579

Query: 655 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGI 699
              D   +  +                DI+ + G LKL+ RELP+PL+   L P F   +
Sbjct: 580 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 639

Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759
           ALS+     + +  L+ S+P PN  T  +LLEHL RV      N+M+ HNL  VFGPTL 
Sbjct: 640 ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 699

Query: 760 RPSEVES 766
           RP +  S
Sbjct: 700 RPEQETS 706


>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
           sapiens]
          Length = 547

 Score =  115 bits (288), Expect = 2e-25
 Identities = 69/187 (36%), Positives = 99/187 (52%), Gaps = 18/187 (9%)

Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFD---A 654
           VFG ++  + +RE   VP  +R C+  V+KRG++  GIYR+SG    +Q L+ + D   A
Sbjct: 336 VFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERA 395

Query: 655 NNKDILLMLSDM---------------DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGI 699
              D   +  +                DI+ + G LKL+ RELP+PL+   L P F   +
Sbjct: 396 VTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAAL 455

Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759
           ALS+     + +  L+ S+P PN  T  +LLEHL RV      N+M+ HNL  VFGPTL 
Sbjct: 456 ALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLF 515

Query: 760 RPSEVES 766
           RP +  S
Sbjct: 516 RPEQETS 522


>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
          Length = 1958

 Score =  115 bits (287), Expect = 2e-25
 Identities = 77/219 (35%), Positives = 111/219 (50%), Gaps = 12/219 (5%)

Query: 587  LKRTPSKKQT--GVFGVKISVVTKRERSK-VPYIVRQCVEEVEKRGIEEVGIYRISGVAT 643
            +++T  KK T  G FGV++        ++ +P IV  C + VE+RG+E  GIYR+ G   
Sbjct: 1131 MRKTFEKKPTATGTFGVRLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNA 1190

Query: 644  DIQALKAVFDANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALS 702
             I +++   +    DI +      D+N I+  LK +FR+LPEPL T+  Y  F+E     
Sbjct: 1191 AISSMQEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKE 1250

Query: 703  DPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPS 762
            DP  +   +  L+  LP+ +  T  FL  HLK VAE    NKM   NLA VFGPTL+R S
Sbjct: 1251 DPLDRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTS 1310

Query: 763  EVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFAE 801
            E      +T   D        Q +++   +QH    F E
Sbjct: 1311 EDNMTHMVTHMPD--------QYKIVETLIQHHDWFFTE 1341


>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
          Length = 468

 Score =  113 bits (282), Expect = 8e-25
 Identities = 64/196 (32%), Positives = 107/196 (54%), Gaps = 4/196 (2%)

Query: 593 KKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVF 652
           K+   V+   ++ + K   ++ P +V  C+ E+E RG++  G+YR+SG    I+ +K  F
Sbjct: 269 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF 328

Query: 653 DANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCM 711
           D + +   +  +   DIN I G LKLYFR+LP P++T   Y  F++   +S+   +   +
Sbjct: 329 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV 388

Query: 712 MHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLT 771
             +L  LP  +  T  +L+ HLK+V   E  N M+  NL  VFGPTL+RP E    + LT
Sbjct: 389 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE---DSTLT 445

Query: 772 SAADIWSHDVMAQVQV 787
           +  D+    ++ Q+ +
Sbjct: 446 TLHDMRYQKLIVQILI 461


>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
          Length = 332

 Score =  113 bits (282), Expect = 8e-25
 Identities = 64/196 (32%), Positives = 107/196 (54%), Gaps = 4/196 (2%)

Query: 593 KKQTGVFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVF 652
           K+   V+   ++ + K   ++ P +V  C+ E+E RG++  G+YR+SG    I+ +K  F
Sbjct: 133 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF 192

Query: 653 DANNKDILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCM 711
           D + +   +  +   DIN I G LKLYFR+LP P++T   Y  F++   +S+   +   +
Sbjct: 193 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV 252

Query: 712 MHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLT 771
             +L  LP  +  T  +L+ HLK+V   E  N M+  NL  VFGPTL+RP E    + LT
Sbjct: 253 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPE---DSTLT 309

Query: 772 SAADIWSHDVMAQVQV 787
           +  D+    ++ Q+ +
Sbjct: 310 TLHDMRYQKLIVQILI 325


>gi|239757684 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 181

 Score =  112 bits (281), Expect = 1e-24
 Identities = 58/93 (62%), Positives = 74/93 (79%), Gaps = 5/93 (5%)

Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759
           ALSDP A+++CM++LL SLP+ NL+TFLFLL+ L+RVAEKE +NKMSLHNLATVFGPTLL
Sbjct: 39  ALSDPVARKSCMLNLLLSLPEANLLTFLFLLDRLERVAEKEAVNKMSLHNLATVFGPTLL 98

Query: 760 RPSEVESK-----AHLTSAADIWSHDVMAQVQV 787
           RPSE ESK     +   +  D  S +VM+Q+Q+
Sbjct: 99  RPSEKESKLPANPSQPITMTDSRSLEVMSQIQI 131


>gi|239752174 PREDICTED: hypothetical protein XP_002348160 [Homo
           sapiens]
          Length = 181

 Score =  112 bits (281), Expect = 1e-24
 Identities = 58/93 (62%), Positives = 74/93 (79%), Gaps = 5/93 (5%)

Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759
           ALSDP A+++CM++LL SLP+ NL+TFLFLL+ L+RVAEKE +NKMSLHNLATVFGPTLL
Sbjct: 39  ALSDPVARKSCMLNLLLSLPEANLLTFLFLLDRLERVAEKEAVNKMSLHNLATVFGPTLL 98

Query: 760 RPSEVESK-----AHLTSAADIWSHDVMAQVQV 787
           RPSE ESK     +   +  D  S +VM+Q+Q+
Sbjct: 99  RPSEKESKLPANPSQPITMTDSRSLEVMSQIQI 131


>gi|239746697 PREDICTED: hypothetical protein XP_002343833 [Homo
           sapiens]
          Length = 181

 Score =  112 bits (281), Expect = 1e-24
 Identities = 58/93 (62%), Positives = 74/93 (79%), Gaps = 5/93 (5%)

Query: 700 ALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLL 759
           ALSDP A+++CM++LL SLP+ NL+TFLFLL+ L+RVAEKE +NKMSLHNLATVFGPTLL
Sbjct: 39  ALSDPVARKSCMLNLLLSLPEANLLTFLFLLDRLERVAEKEAVNKMSLHNLATVFGPTLL 98

Query: 760 RPSEVESK-----AHLTSAADIWSHDVMAQVQV 787
           RPSE ESK     +   +  D  S +VM+Q+Q+
Sbjct: 99  RPSEKESKLPANPSQPITMTDSRSLEVMSQIQI 131


>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
          Length = 1397

 Score =  112 bits (279), Expect = 2e-24
 Identities = 67/167 (40%), Positives = 89/167 (53%), Gaps = 2/167 (1%)

Query: 599 FGVKISVVTKR-ERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657
           FGV++       E  +VP IV  C   VE RG+E  GIYR+ G    + +L+   +    
Sbjct: 809 FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPG 868

Query: 658 DILLMLSD-MDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLR 716
           DI L      D+N I+  LK +FR+LPEPL TD  Y  F+E   + D   +   +  L+R
Sbjct: 869 DINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIR 928

Query: 717 SLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSE 763
            LP     T  FL+ HLK +A+    NKM   NLA VFGPTL+R SE
Sbjct: 929 DLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSE 975


>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
          Length = 2087

 Score =  111 bits (278), Expect = 2e-24
 Identities = 83/256 (32%), Positives = 132/256 (51%), Gaps = 20/256 (7%)

Query: 554 PQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMSLKRTPSK---KQTG-----VFGVKISV 605
           PQ+V T +    V + +G  + F   F      +K  P+K   KQ G     VFG  +  
Sbjct: 324 PQSV-TNSVPKPVSKKHGKLITFLRTF------MKSRPTKQKLKQRGILKERVFGCDLGE 376

Query: 606 VTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANN-KDILLMLS 664
                  +VP +++ C   +E+ GI + GIYR+SGVA++IQ L+  FD+ +  D+     
Sbjct: 377 HLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRHEFDSEHVPDLTKEPY 435

Query: 665 DMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMMHLLRSLPDPNLI 724
             DI+++    KLYFRELP PLLT +LY  F + ++ +    +   +  +++ LP P+  
Sbjct: 436 VQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYR 495

Query: 725 TFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDVMAQ 784
           T  FL+ HL  +A+   I  M   NLA V+ P LLR  ++ES     +AA +   +V  Q
Sbjct: 496 TLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFM---EVRIQ 552

Query: 785 VQVLLYYLQHPPISFA 800
             V+ + L H  + F+
Sbjct: 553 SVVVEFILNHVDVLFS 568


>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
          Length = 1738

 Score =  111 bits (277), Expect = 3e-24
 Identities = 75/223 (33%), Positives = 119/223 (53%), Gaps = 13/223 (5%)

Query: 587 LKRTPSK---KQTG-----VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRI 638
           +K  P+K   KQ G     VFG  +         +VP +++ C   +E+ GI + GIYR+
Sbjct: 1   MKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVD-GIYRL 59

Query: 639 SGVATDIQALKAVFDANN-KDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFME 697
           SGVA++IQ L+  FD+ +  D+       DI+++    KLYFRELP PLLT +LY  F +
Sbjct: 60  SGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKFSD 119

Query: 698 GIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPT 757
            ++ +    +   +  +++ LP P+  T  FL+ HL  +A+   I  M   NLA V+ P 
Sbjct: 120 AVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPN 179

Query: 758 LLRPSEVESKAHLTSAADIWSHDVMAQVQVLLYYLQHPPISFA 800
           LLR  ++ES     +AA +   +V  Q  V+ + L H  + F+
Sbjct: 180 LLRSKQIESACFSGTAAFM---EVRIQSVVVEFILNHVDVLFS 219


>gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Homo
            sapiens]
          Length = 2063

 Score =  109 bits (273), Expect = 9e-24
 Identities = 84/327 (25%), Positives = 146/327 (44%), Gaps = 58/327 (17%)

Query: 29   PPEGLAPGVEAGKG--------LEMRKLVLSGFLASEEIYINQLEALLLP-MKPLKA--T 77
            PPE   P  E            ++MRK V    L +E+ Y+  L  L+   M+PLK    
Sbjct: 1042 PPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPEN 1101

Query: 78   ATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ--- 134
            +    P L    ++ IF +I ++ E H++F + +   +Q W +Q  +G L  +  S+   
Sbjct: 1102 SVLCDPSL----VDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVL 1157

Query: 135  LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPI 194
            + +Y A++DN+  A +      ++   F K  E+         +++     +  L+ KP+
Sbjct: 1158 VNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQ-------SMRENKEKQALSDLMIKPV 1210

Query: 195  DRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSIN----------------ED 238
             R+ R  L++ DLLKHTP DHPD+PLL +A R  +     IN                ++
Sbjct: 1211 QRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQE 1270

Query: 239  IDPRRTAVTTPKGETRQLVKDGFLVEVSE-SSRKLRHVFLFTDVLLCAKLKKTSAGKHQ- 296
            I+     +   +   R+ ++   ++EV     +K R +FLFTD+++C  LK+ S    + 
Sbjct: 1271 IEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRS 1330

Query: 297  ---------------QYDCKWYIPLAD 308
                           +Y   W +PL D
Sbjct: 1331 SMSLYTAASVIDTASKYKMLWKLPLED 1357


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score =  109 bits (273), Expect = 9e-24
 Identities = 75/207 (36%), Positives = 112/207 (54%), Gaps = 9/207 (4%)

Query: 598 VFGVKISVVTKRERSKVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK 657
           VFG  +          VP ++R C E +E  G+ + GIYR+SGV+++IQ L+  FD+   
Sbjct: 312 VFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVD-GIYRLSGVSSNIQRLRHEFDSERI 370

Query: 658 DILLMLSDM-DINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSDPAAKENCMM--HL 714
             L   + + DI++++   KLYFRELP PLLT +LY  F E  A+S P  +E  +    +
Sbjct: 371 PELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSE--AMSVPGEEERLVRVHDV 428

Query: 715 LRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAA 774
           ++ LP P+  T  +LL HL R+A       M   NLA V+ P LLR  E+ES     +AA
Sbjct: 429 IQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAA 488

Query: 775 DIWSHDVMAQVQVLLYYLQHPPISFAE 801
                +V  Q  V+ + L H  + F++
Sbjct: 489 ---FREVRVQSVVVEFLLTHVDVLFSD 512


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,834,891
Number of Sequences: 37866
Number of extensions: 1318244
Number of successful extensions: 5146
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 4717
Number of HSP's gapped (non-prelim): 296
length of query: 813
length of database: 18,247,518
effective HSP length: 111
effective length of query: 702
effective length of database: 14,044,392
effective search space: 9859163184
effective search space used: 9859163184
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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