Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 227499619
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
(620 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 1264 0.0
gi|227499621 solute carrier family 27 (fatty acid transporter), ... 1122 0.0
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 648 0.0
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 648 0.0
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 559 e-159
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 506 e-143
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 404 e-112
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 396 e-110
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 75 1e-13
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 72 1e-12
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 72 2e-12
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 70 6e-12
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 70 6e-12
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 67 5e-11
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 67 5e-11
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 61 3e-09
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 60 5e-09
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 59 2e-08
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 55 2e-07
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 55 2e-07
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 53 7e-07
gi|27477105 lipidosin [Homo sapiens] 48 3e-05
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 45 2e-04
gi|4758332 acyl-CoA synthetase long-chain family member 4 isofor... 45 3e-04
gi|12669909 acyl-CoA synthetase long-chain family member 4 isofo... 45 3e-04
gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens] 44 3e-04
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 44 3e-04
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 43 8e-04
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 43 0.001
gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo... 43 0.001
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 1264 bits (3271), Expect = 0.0
Identities = 620/620 (100%), Positives = 620/620 (100%)
Query: 1 MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFL 60
MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFL
Sbjct: 1 MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFL 60
Query: 61 EKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWL 120
EKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWL
Sbjct: 61 EKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWL 120
Query: 121 WLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIY 180
WLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIY
Sbjct: 121 WLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIY 180
Query: 181 YVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQ 240
YVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQ
Sbjct: 181 YVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQ 240
Query: 241 RIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDD 300
RIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDD
Sbjct: 241 RIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDD 300
Query: 301 CRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYE 360
CRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYE
Sbjct: 301 CRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYE 360
Query: 361 FYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKG 420
FYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKG
Sbjct: 361 FYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKG 420
Query: 421 EVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDR 480
EVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDR
Sbjct: 421 EVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDR 480
Query: 481 VGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGK 540
VGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGK
Sbjct: 481 VGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGK 540
Query: 541 KLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAK 600
KLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAK
Sbjct: 541 KLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAK 600
Query: 601 MYVPMTEDIYNAISAKTLKL 620
MYVPMTEDIYNAISAKTLKL
Sbjct: 601 MYVPMTEDIYNAISAKTLKL 620
>gi|227499621 solute carrier family 27 (fatty acid transporter),
member 2 isoform 2 [Homo sapiens]
Length = 567
Score = 1122 bits (2903), Expect = 0.0
Identities = 564/620 (90%), Positives = 565/620 (91%), Gaps = 53/620 (8%)
Query: 1 MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFL 60
MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFL
Sbjct: 1 MLSAIYTVLAGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAFL 60
Query: 61 EKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWL 120
EKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWL
Sbjct: 61 EKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWL 120
Query: 121 WLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIY 180
WLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIY
Sbjct: 121 WLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIY 180
Query: 181 YVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQ 240
YVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIY T+G
Sbjct: 181 YVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIY---TSG---------- 227
Query: 241 RIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDD 300
GATLALRTKFSASQFWDD
Sbjct: 228 ----------------------------------------TTGATLALRTKFSASQFWDD 247
Query: 301 CRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYE 360
CRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYE
Sbjct: 248 CRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYE 307
Query: 361 FYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKG 420
FYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKG
Sbjct: 308 FYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKG 367
Query: 421 EVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDR 480
EVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDR
Sbjct: 368 EVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDR 427
Query: 481 VGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGK 540
VGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGK
Sbjct: 428 VGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGK 487
Query: 541 KLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAK 600
KLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAK
Sbjct: 488 KLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAK 547
Query: 601 MYVPMTEDIYNAISAKTLKL 620
MYVPMTEDIYNAISAKTLKL
Sbjct: 548 MYVPMTEDIYNAISAKTLKL 567
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 648 bits (1672), Expect = 0.0
Identities = 316/621 (50%), Positives = 431/621 (69%), Gaps = 3/621 (0%)
Query: 1 MLSAIYTVL-AGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAF 59
ML + TVL AG++ L L L PYF+ D + LKV + R++ Y KR T+L F
Sbjct: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
Query: 60 LEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVW 119
L A++ P KPF+++ + TY VD+RS++VA +H L++GD VALLM NEP +V
Sbjct: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
Query: 120 LWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSI 179
+W GL KLGC +A LN NIR+ SLL+C + CG + L+V +L VEEILPSL +++S+
Sbjct: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLS-ENISV 179
Query: 180 YYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITH 239
+ + + S G+ S +K+ EP+P S + LYI+TSGTTGLPKAA+I+
Sbjct: 180 WGM-KDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQ 238
Query: 240 QRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWD 299
++ G+ + + G A D++YITLP YHS+A ++GI GC+ GAT L+ KFSASQFW
Sbjct: 239 LQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWS 298
Query: 300 DCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIY 359
DC+KY+VTV QYIGEL RYLC ++ ++DHKVRLA+GNG+R DVWR+F+ RFG+I +
Sbjct: 299 DCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVC 358
Query: 360 EFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPK 419
E YAATE +I FMNY ++GA+GR N K + T+DLIKYD +KDEP+R+E G+C+ V K
Sbjct: 359 ELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKK 418
Query: 420 GEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHD 479
GE GLL+ ++ PF GYAG T+ K L DVFKKGD+Y N+GDL++ D +NF+YF D
Sbjct: 419 GEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWD 478
Query: 480 RVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDG 539
R GDTFRWKGENVATTEVAD +G++DF+QE NVYGV + +EGR GMASI +K N D
Sbjct: 479 RTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDL 538
Query: 540 KKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTA 599
+K+++ + +LP+YA PRFLRIQ+ +E TGTFK K LVE+GFNP I + LYF+D+
Sbjct: 539 EKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLK 598
Query: 600 KMYVPMTEDIYNAISAKTLKL 620
K YV +T ++Y+ I +KL
Sbjct: 599 KSYVLLTRELYDQIMLGEIKL 619
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 648 bits (1672), Expect = 0.0
Identities = 316/621 (50%), Positives = 431/621 (69%), Gaps = 3/621 (0%)
Query: 1 MLSAIYTVL-AGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAF 59
ML + TVL AG++ L L L PYF+ D + LKV + R++ Y KR T+L F
Sbjct: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
Query: 60 LEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVW 119
L A++ P KPF+++ + TY VD+RS++VA +H L++GD VALLM NEP +V
Sbjct: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
Query: 120 LWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSI 179
+W GL KLGC +A LN NIR+ SLL+C + CG + L+V +L VEEILPSL +++S+
Sbjct: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLS-ENISV 179
Query: 180 YYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITH 239
+ + + S G+ S +K+ EP+P S + LYI+TSGTTGLPKAA+I+
Sbjct: 180 WGM-KDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQ 238
Query: 240 QRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWD 299
++ G+ + + G A D++YITLP YHS+A ++GI GC+ GAT L+ KFSASQFW
Sbjct: 239 LQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWS 298
Query: 300 DCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIY 359
DC+KY+VTV QYIGEL RYLC ++ ++DHKVRLA+GNG+R DVWR+F+ RFG+I +
Sbjct: 299 DCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVC 358
Query: 360 EFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPK 419
E YAATE +I FMNY ++GA+GR N K + T+DLIKYD +KDEP+R+E G+C+ V K
Sbjct: 359 ELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKK 418
Query: 420 GEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHD 479
GE GLL+ ++ PF GYAG T+ K L DVFKKGD+Y N+GDL++ D +NF+YF D
Sbjct: 419 GEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWD 478
Query: 480 RVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDG 539
R GDTFRWKGENVATTEVAD +G++DF+QE NVYGV + +EGR GMASI +K N D
Sbjct: 479 RTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDL 538
Query: 540 KKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTA 599
+K+++ + +LP+YA PRFLRIQ+ +E TGTFK K LVE+GFNP I + LYF+D+
Sbjct: 539 EKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLK 598
Query: 600 KMYVPMTEDIYNAISAKTLKL 620
K YV +T ++Y+ I +KL
Sbjct: 599 KSYVLLTRELYDQIMLGEIKL 619
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 559 bits (1441), Expect = e-159
Identities = 275/601 (45%), Positives = 401/601 (66%), Gaps = 9/601 (1%)
Query: 29 DIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFRDE---TLTYAQVD 85
D+ + K+ +G ++R R+P T + AF +AR P + L++ ++T+ ++D
Sbjct: 90 DVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELD 149
Query: 86 RRSNQVARALHDHLG----LRQGDCVALLMGNEPAY--VWLWLGLVKLGCAMACLNYNIR 139
R+ Q A AL LG L G+ ALL+ A + +WLGL KLGC A +N + R
Sbjct: 150 ARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGR 209
Query: 140 AKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVD 199
L H GA+VL+V P+L+ ++EEILP L+ +++ +Y+S TS T G+ + +D
Sbjct: 210 GMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD 269
Query: 200 EVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLKADDV 259
+ P+P R+ +T+ +PAL+IYTSGTTGLPK A++TH+R+ + + +SG ADDV
Sbjct: 270 AAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDV 329
Query: 260 IYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYL 319
+Y LP YH L++GI GC+ GAT L KFS S FWDDCR++ VTVI Y+GELLRYL
Sbjct: 330 VYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYL 389
Query: 320 CNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVG 379
CN PQ+P DR H VRLA+GNGLR DVW F +RFG I I+E Y +TEGN+G +NY + G
Sbjct: 390 CNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCG 449
Query: 380 AVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYA 439
A+G+++ L + + ++L+++D+E EPVRD G+C+ V GE GLL+ K+ PF GY
Sbjct: 450 ALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYR 509
Query: 440 GAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVAD 499
G + +E+K +R+V + GD+Y+N+GD+L +D E F+YF DR+GDTFRWKGENV+T EV
Sbjct: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569
Query: 500 TVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFL 559
+ VDF+Q+VNVYGV VP EG++GMA++++ FDG+KL+QH+ +LP+YA P F+
Sbjct: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629
Query: 560 RIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLK 619
RIQD +E+T TFK K LV EGFN ++ D L+ LD+ A+ + P+T ++Y A+ T +
Sbjct: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689
Query: 620 L 620
L
Sbjct: 690 L 690
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 506 bits (1304), Expect = e-143
Identities = 245/520 (47%), Positives = 342/520 (65%)
Query: 101 LRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPE 160
L G VALL+ P ++WLW GL K G A + +R LLHC + CGA+ L+++PE
Sbjct: 211 LSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARALVLAPE 270
Query: 161 LQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPA 220
++E LP+L+ + ++ ++ GI L +V P+P S + +
Sbjct: 271 FLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQSITDTC 330
Query: 221 LYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCI 280
LYI+TSGTTGLPKAA I+H +I G + G+ +DVIY+ LP YH + L+GI GC+
Sbjct: 331 LYIFTSGTTGLPKAARISHLKILQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCM 390
Query: 281 VAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNG 340
GAT+ L++KFSA QFW+DC+++ VTV QYIGEL RYL N P +R HKVRLA+G+G
Sbjct: 391 GIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERGHKVRLAVGSG 450
Query: 341 LRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYD 400
LR D W +FV+RFG + + E Y TEGN+ +NY + GAVGR ++L K I + LI+YD
Sbjct: 451 LRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLYKHIFPFSLIRYD 510
Query: 401 VEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLY 460
V EP+RD G+C+ GE GLLV ++Q +PF GYAG + K L+DVF+ GD++
Sbjct: 511 VTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVF 570
Query: 461 FNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDH 520
FN+GDLL+ D + F+ FHDR GDTFRWKGENVATTEVA+ +DF+QEVNVYGV VP H
Sbjct: 571 FNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGH 630
Query: 521 EGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVE 580
EGR GMA++ ++ H D +L+ H+++ LP YARPRFLR+Q+++ T TFK +K+ +
Sbjct: 631 EGRAGMAALVLRPPHALDLMQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMAN 690
Query: 581 EGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL 620
EGF+P+ + D LY LD Y+P+T Y+A+ A L++
Sbjct: 691 EGFDPSTLSDPLYVLDQAVGAYLPLTTARYSALLAGNLRI 730
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 404 bits (1038), Expect = e-112
Identities = 241/603 (39%), Positives = 342/603 (56%), Gaps = 20/603 (3%)
Query: 28 QDIGYFLKVAAVGRRVRSYGKRRPARTILRAFLEKARQTPHKPFLLFR--DETLTYAQVD 85
+DI L + V +VR + R RT+ F R+ P K L+F D T+ Q+D
Sbjct: 51 RDIFGGLVLLKVKAKVRQCLQER--RTVPILFASTVRRHPDKTALIFEGTDTHWTFRQLD 108
Query: 86 RRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLH 145
S+ VA L GL GD A+ M N +V LWLG+ KLG A +N N+R +LLH
Sbjct: 109 EYSSSVANFLQAR-GLASGDVAAIFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALLH 167
Query: 146 CFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGI----DSFLDKVDEV 201
C A+ L+ E+ +A+ E+ SL D S+ S G LD + +
Sbjct: 168 CLTTSRARALVFGSEMASAICEVHASL---DPSLSLFCSGSWEPGAVPPSTEHLDPLLKD 224
Query: 202 STEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVS-GLKADDVI 260
+ + +P + F+ YIYTSGTTGLPKAA++ H R + L + ++ +D++
Sbjct: 225 APKHLPSC--PDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMAALVYYGFRMRPNDIV 282
Query: 261 YITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLC 320
Y LP YHSA ++GI C++ G T+ +R KFSAS+FWDDC KYN T++QYIGEL RYL
Sbjct: 283 YDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLL 342
Query: 321 NSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGA 380
N P + + H+VR+ALGNGLR +W F RF + EFY ATE N N+ +VGA
Sbjct: 343 NQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGATECNCSLGNFDSQVGA 402
Query: 381 VGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTP---FNG 437
G + + + L++ + + E +R +G C+ GE G LV +I Q P F+G
Sbjct: 403 CGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQLVGRIIQKDPLRRFDG 462
Query: 438 YAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEV 497
Y A KK +DVFKKGD + +GD+L++D ++YF DR GDTFRWKGENV+TTEV
Sbjct: 463 YLNQGA-NNKKIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEV 521
Query: 498 ADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPR 557
T+ + + +V VYGV VP EGR GMA++ + D ++ Q + LP YARP
Sbjct: 522 EGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVASPTGN-CDLERFAQVLEKELPLYARPI 580
Query: 558 FLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKT 617
FLR+ + TGT+K +K L +EGF+PA++KD L++LD YVP+ ++ Y+ I A
Sbjct: 581 FLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRYVPLDQEAYSRIQAGE 640
Query: 618 LKL 620
KL
Sbjct: 641 EKL 643
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 396 bits (1018), Expect = e-110
Identities = 244/585 (41%), Positives = 324/585 (55%), Gaps = 23/585 (3%)
Query: 49 RRPARTILRAFLEKARQTPHKPFLLFRD--ETLTYAQVDRRSNQVARALHDHLGLRQGDC 106
+R TI R F ++ P + L+ E T+AQ+D SN VA L LG GD
Sbjct: 72 QRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVAN-LFRQLGFAPGDV 130
Query: 107 VALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVE 166
VA+ + P +V LWLGL K G A LN N+R + L C GAK L+ E+ AAV
Sbjct: 131 VAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALIFGGEMVAAVA 190
Query: 167 EILPSLKKDDVSIYYVSRTSNTDGI---DSFLDKV-DEVSTEP---IPESWRSEVTFSTP 219
E+ L K I + S +GI LD + E ST P IP + F
Sbjct: 191 EVSGHLGKS--LIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGMDDRLF--- 245
Query: 220 ALYIYTSGTTGLPKAAMITHQRIWYGTGLTFVS-GLKADDVIYITLPFYHSAALLIGIHG 278
YIYTSGTTGLPKAA++ H R + + ++A DV+Y LP YHSA +IG+
Sbjct: 246 --YIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIGVGQ 303
Query: 279 CIVAGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALG 338
C++ G T+ LR KFSAS+FWDDC KYN TV+QYIGE+ RYL P + +R H+VRLA+G
Sbjct: 304 CLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRLAVG 363
Query: 339 NGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIK 398
NGLR +W +F +RFG I EFY ATE N N KVG+ G + + + L+K
Sbjct: 364 NGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIRLVK 423
Query: 399 YDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTP---FNGYAGAKAQTEKKKLRDVFK 455
+ + E +RD G C+ GE GLLV +I Q P F+GY A T KK VF
Sbjct: 424 VNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESA-TSKKIAHSVFS 482
Query: 456 KGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGV 515
KGD + SGD+L++D ++YF DR GDTFRW+GENV+TTEV + + +V VYGV
Sbjct: 483 KGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVYGV 542
Query: 516 HVPDHEGRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRK 575
VP EG+ GMA++ + D ++Q + L YARP FLR+ ++ TGTFK +K
Sbjct: 543 AVPGVEGKAGMAAV-ADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQK 601
Query: 576 MTLVEEGFNPAVIKDALYFLDDTAKMYVPMTEDIYNAISAKTLKL 620
L EGF+P D L+FLD Y+P+ E +Y I + L
Sbjct: 602 TRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL 646
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 75.5 bits (184), Expect = 1e-13
Identities = 123/539 (22%), Positives = 214/539 (39%), Gaps = 47/539 (8%)
Query: 61 EKARQTPHKPFLLF----RDETL-TYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEP 115
EK + P P L + DE ++ ++ S + A L GL++GD +A+++ P
Sbjct: 66 EKTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIP 125
Query: 116 AYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKD 175
+ + + ++ G + AK +L+ + AK ++ S E+ AVE I+ L+
Sbjct: 126 EWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVESIV--LECP 183
Query: 176 DVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAA 235
D+ + + +G SF + S E S+ P +TSGTTG PK
Sbjct: 184 DLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQ----EPMTIYFTSGTTGFPK-- 237
Query: 236 MITHQRIWYGTGLTFVS----GLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALR-- 289
M H + G G T LK+ D+I+ A + + + GA + +
Sbjct: 238 MAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRM 297
Query: 290 TKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKP-NDRDHKVRLALGNGLRGDVWRQ 348
+F F D Y +T + + R L K + + L G L +V Q
Sbjct: 298 AQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQ 357
Query: 349 FVKRFGDICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVR 408
+ + G + +YE Y TE +G M A + G + + K ++ YD+ +
Sbjct: 358 WRVQTG-LELYEGYGQTE--VG-MICANQKGQEIKPGSMGKGMLPYDV---------QII 404
Query: 409 DENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLM 468
DENG +P G+ G + ++ PF ++ +K +GD Y +GD +
Sbjct: 405 DENGNV--LPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTA---ATIRGDFYV-TGDRGV 458
Query: 469 VDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDH-EGRIGMA 527
+D + + +F R D G + EV L++ V V PD G + A
Sbjct: 459 MDSDGYFWFVGRADDVIISSGYRIGPFEVES--ALIEHPAVVESAVVSSPDQIRGEVVKA 516
Query: 528 SIKM-----KENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEE 581
+ + N E +L H+ Y PR + + T T K ++ L ++
Sbjct: 517 FVVLAAPFKSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQ 575
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 72.4 bits (176), Expect = 1e-12
Identities = 123/576 (21%), Positives = 230/576 (39%), Gaps = 76/576 (13%)
Query: 48 KRRPARTILRAFLEKARQTPHKPFL--LFRDETLTYAQVDRRSNQVARALHDHLGLRQGD 105
K ++T+ + A++ P + L L D LT+AQ+ ++ A L +GL +GD
Sbjct: 67 KHLNSKTVGQCLETTAQRVPEREALVVLHEDVRLTFAQLKEEVDKAASGLLS-IGLCKGD 125
Query: 106 CVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLL--------- 156
+ + N A+V + L + G + +N +A L + + G K L+
Sbjct: 126 RLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAMELEYVLKKVGCKALVFPKQFKTQQ 185
Query: 157 -------VSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPES 209
+ PE++ A L S + D++ +S + G + V ST +
Sbjct: 186 YYNVLKQICPEVENAQPGALKSQRLPDLTTV-ISVDAPLPGTLLLDEVVAAGSTRQHLDQ 244
Query: 210 WRSEVTFST---PALYIYTSGTTGLPKAAMITHQRIWYGT---GLTFVSGLKADDVIYIT 263
+ F + P +TSGTTG PK A ++H I + G K + + +
Sbjct: 245 LQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNIVNNSNILGERLKLHEKTPEQLRMI 304
Query: 264 LP--FYHSAALLIGIHGCIVAGATLALRTK-FSASQFWDDCRKYNVTVIQYIGELLRYLC 320
LP YH + G C++ GATL L + F+ + + + T + + +
Sbjct: 305 LPNPLYHCLGSVAGTMMCLMYGATLILASPIFNGKKALEAISRERGTFLYGTPTMFVDIL 364
Query: 321 NSPQKPNDRDHKVRLALGNGLRG-----DVWRQFVKRFGDICIYEFYAATEGN-IGFMNY 374
N +P+ + + G + G ++ R + + + Y TE + + F ++
Sbjct: 365 N---QPDFSSYDISTMCGGVIAGSPAPPELIRAIINKINMKDLVVAYGTTENSPVTFAHF 421
Query: 375 A-----RKVGAVGRVN-YLQKKIITYD---LIKYDVEKDEPVRDENGYCVRVPKGEVGLL 425
+K +VGR+ + + +I+ + L K + + +R GYCV +
Sbjct: 422 PEDTVEQKAESVGRIMPHTEARIMNMEAGTLAKLNTPGELCIR---GYCVML-------- 470
Query: 426 VCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTF 485
GY G +TE+ +D ++ +GD+ ++ + F R D
Sbjct: 471 -----------GYWGEPQKTEEAVDQDK------WYWTGDVATMNEQGFCKIVGRSKDMI 513
Query: 486 RWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGKKLFQH 545
GEN+ E+ D VQEV V GV D G A I++K+ E +++
Sbjct: 514 IRGGENIYPAELEDFFHTHPKVQEVQVVGVK-DDRMGEEICACIRLKDGEETTVEEIKAF 572
Query: 546 IADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEE 581
+ + P+++ +T + K +K L E+
Sbjct: 573 CKGKISHFKIPKYIVFVTNYPLTISGKIQKFKLREQ 608
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 72.0 bits (175), Expect = 2e-12
Identities = 120/535 (22%), Positives = 203/535 (37%), Gaps = 78/535 (14%)
Query: 80 TYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIR 139
++ ++ + +VA GL+QGD +AL++ P + + +G ++ G ++
Sbjct: 87 SFREMGDLTRRVANVFTQTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPATILLK 146
Query: 140 AKSLLHCFQCCGAKVLLVSPELQAAVEEI---LPSLKKDDVSIYYVSRTSNTDGIDSFLD 196
AK +L+ Q AK ++ L + V+ I PSLK + VS S +D F
Sbjct: 147 AKDILYRLQLSKAKGIVTIDALASEVDSIASQCPSLK----TKLLVSDHSREGWLD-FRS 201
Query: 197 KVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGT--GLTFVSGL 254
V S PE + P + +TSGTTG PK A +H + G + L
Sbjct: 202 LVKSAS----PEHTCVKSKTLDPMVIFFTSGTTGFPKMAKHSHGLALQPSFPGSRKLRSL 257
Query: 255 KADDVIYI------------TLPFYHSAALLIGIHGCIVAGATLALRT--KFSASQFWDD 300
K DV + TL +A + IH + ++T K+ + FW
Sbjct: 258 KTSDVSWCLSDSGWIVATIWTLVEPWTAGCTVFIHHLPQFDTKVIIQTLLKYPINHFWGV 317
Query: 301 CRKYNV------TVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFG 354
Y + T I++ Y P D++ W KR
Sbjct: 318 SSIYRMILQQDFTSIRFPALEHCYTGGEVVLPKDQEE--------------W----KRRT 359
Query: 355 DICIYEFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYC 414
+ +YE Y +E + Y G + ++ K YD+ + + D+
Sbjct: 360 GLLLYENYGQSETGLICATY---WGMKIKPGFMGKATPPYDV--------QVIDDKGSIL 408
Query: 415 VRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENF 474
+G +G+ + + ++ F Y G +T K + D ++N+GD +D E +
Sbjct: 409 PPNTEGNIGIRIKPVRPVSLFMCYEGDPEKTAKVECGD-------FYNTGDRGKMDEEGY 461
Query: 475 IYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKE- 533
I F R D G + EV + V E V G P G + A I +
Sbjct: 462 ICFLGRSDDIINASGYRIGPAEVESALVEHPAVAESAVVGSPDP-IRGEVVKAFIVLTPQ 520
Query: 534 --NHEFD--GKKLFQHIADYLPSYARPRFLRIQDTI--EITGTFKHRKMTLVEEG 582
+H+ D K+L QH+ Y PR + + ITG + +++ E G
Sbjct: 521 FLSHDKDQLTKELQQHVKSVTAPYKYPRKVEFVSELPKTITGKIERKELRKKETG 575
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 70.1 bits (170), Expect = 6e-12
Identities = 131/546 (23%), Positives = 219/546 (40%), Gaps = 75/546 (13%)
Query: 80 TYAQVDRRSNQVARALHDHLGLRQGDC----VALLMGNEPAYVWL-WLGLVKLGCAMACL 134
TY ++ RS ++++ + G GD V+ L N+ +YV W + G A+
Sbjct: 67 TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126
Query: 135 NYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSF 194
+ A+ L + + V+L S E +E + P ++K V + ++ T
Sbjct: 127 RKHPAAQ-LEYVICDSQSSVVLASQEY---LELLSPVVRKLGVPLLPLTPAIYTGA---- 178
Query: 195 LDKVDEVSTEPIPES-WRSEVTFSTPALYIYTSGTTGLPKAAMITHQRI-WYGTGLTFVS 252
V+E + P+PE WR++ A+ IYTSGTTG PK + THQ I TGL
Sbjct: 179 ---VEEPAEVPVPEQGWRNK-----GAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW 230
Query: 253 GLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWD-----DCRKYNV- 306
DDVI LP +H ++ + + GAT + +FS Q W+ + + NV
Sbjct: 231 AWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVF 290
Query: 307 -TVIQYIGELLRYLCNSPQKPNDRD-------HKVRLALGN--GLRGDVWRQFVKRFGDI 356
V +L+ Y +P+ +D K+RL + L V ++ K
Sbjct: 291 MAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKW-KNITGH 349
Query: 357 CIYEFYAATEGNIG----FMNYARKVGAVGR-VNYLQKKIITYDLIKYDVEKDEPVRDEN 411
+ E Y TE + R G+VG + +Q +I++ + P R+
Sbjct: 350 TLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVS----------ENPQREAC 399
Query: 412 GYCVRVPKGEVGLLVCKITQLTP-FNGYAGAKAQTEKKKLRDVFKKG---------DLYF 461
Y + E G T++TP F G R+ + K D +F
Sbjct: 400 SYTIHAEGDERG------TKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWF 453
Query: 462 NSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHE 521
+GD ++ + D + G V+ EV + + +V V G VPD
Sbjct: 454 KTGDTVVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIG--VPDMT 511
Query: 522 -GRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVE 580
G+ A + ++E H ++L + + L YA P L + + I K K L+
Sbjct: 512 WGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIR 571
Query: 581 EGFNPA 586
F+P+
Sbjct: 572 H-FHPS 576
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 70.1 bits (170), Expect = 6e-12
Identities = 131/546 (23%), Positives = 219/546 (40%), Gaps = 75/546 (13%)
Query: 80 TYAQVDRRSNQVARALHDHLGLRQGDC----VALLMGNEPAYVWL-WLGLVKLGCAMACL 134
TY ++ RS ++++ + G GD V+ L N+ +YV W + G A+
Sbjct: 67 TYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLY 126
Query: 135 NYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSF 194
+ A+ L + + V+L S E +E + P ++K V + ++ T
Sbjct: 127 RKHPAAQ-LEYVICDSQSSVVLASQEY---LELLSPVVRKLGVPLLPLTPAIYTGA---- 178
Query: 195 LDKVDEVSTEPIPES-WRSEVTFSTPALYIYTSGTTGLPKAAMITHQRI-WYGTGLTFVS 252
V+E + P+PE WR++ A+ IYTSGTTG PK + THQ I TGL
Sbjct: 179 ---VEEPAEVPVPEQGWRNK-----GAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKW 230
Query: 253 GLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWD-----DCRKYNV- 306
DDVI LP +H ++ + + GAT + +FS Q W+ + + NV
Sbjct: 231 AWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVF 290
Query: 307 -TVIQYIGELLRYLCNSPQKPNDRD-------HKVRLALGN--GLRGDVWRQFVKRFGDI 356
V +L+ Y +P+ +D K+RL + L V ++ K
Sbjct: 291 MAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKW-KNITGH 349
Query: 357 CIYEFYAATEGNIG----FMNYARKVGAVGR-VNYLQKKIITYDLIKYDVEKDEPVRDEN 411
+ E Y TE + R G+VG + +Q +I++ + P R+
Sbjct: 350 TLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVS----------ENPQREAC 399
Query: 412 GYCVRVPKGEVGLLVCKITQLTP-FNGYAGAKAQTEKKKLRDVFKKG---------DLYF 461
Y + E G T++TP F G R+ + K D +F
Sbjct: 400 SYTIHAEGDERG------TKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWF 453
Query: 462 NSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHE 521
+GD ++ + D + G V+ EV + + +V V G VPD
Sbjct: 454 KTGDTVVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIG--VPDMT 511
Query: 522 -GRIGMASIKMKENHEFDGKKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVE 580
G+ A + ++E H ++L + + L YA P L + + I K K L+
Sbjct: 512 WGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIR 571
Query: 581 EGFNPA 586
F+P+
Sbjct: 572 H-FHPS 576
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 67.0 bits (162), Expect = 5e-11
Identities = 113/517 (21%), Positives = 205/517 (39%), Gaps = 55/517 (10%)
Query: 81 YAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRA 140
+ ++ S Q A L GL++GD VA+++ P + + LG ++ G +++
Sbjct: 83 FRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 141 KSLLHCFQCCGAKVLLVSPELQAAVEEI---LPSLKKDDVSIYYVSRTSNTDGIDSFLDK 197
+L+ Q AK ++ E+ V+ + PSL+ I + + DG +F
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLR-----IKLLVSEKSCDGWLNFKKL 197
Query: 198 VDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGL-TFVSGLK 255
++E S T E+ E + A+Y +TSGT+GLPK A ++ + + +GL+
Sbjct: 198 LNEASTTHHCVETGSQEAS----AIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQ 252
Query: 256 ADDVIYITLPFYHSAALLIGIHGCIVAGATLA------LRTKFSASQFWDDCRKYNVTVI 309
A D+++ ++ I G ++ TL L KF Y + +
Sbjct: 253 ASDIMWT----ISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSM 308
Query: 310 QYIGELLRYLCNSPQKPNDRDHKVR-LALGNGLRGDVWRQFVKRFGDICIYEFYAATEGN 368
+ R L H LA G L + + + G + I EFY TE
Sbjct: 309 MGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTETG 367
Query: 369 IGFM-NYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVC 427
+ M + K+ + Y+ YD+ + + D+ +G++G+ V
Sbjct: 368 LTCMVSKTMKI----KPGYMGTAASCYDV--------QVIDDKGNVLPPGTEGDIGIRVK 415
Query: 428 KITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRW 487
I + F+GY + K ++ +GD + GD + D + + F R D
Sbjct: 416 PIRPIGIFSGY----VENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIINS 468
Query: 488 KGENVATTEVADTVGLVDFVQEVNVYGVHVPDH------EGRIGMASIKMKENHEFDGKK 541
G + +EV + + V E V + PD + + +AS + + E K+
Sbjct: 469 SGYRIGPSEVENALMKHPAVVETAV--ISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 526
Query: 542 LFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTL 578
L QH+ Y PR + + T T K ++ L
Sbjct: 527 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 67.0 bits (162), Expect = 5e-11
Identities = 113/517 (21%), Positives = 205/517 (39%), Gaps = 55/517 (10%)
Query: 81 YAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRA 140
+ ++ S Q A L GL++GD VA+++ P + + LG ++ G +++
Sbjct: 83 FRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 141 KSLLHCFQCCGAKVLLVSPELQAAVEEI---LPSLKKDDVSIYYVSRTSNTDGIDSFLDK 197
+L+ Q AK ++ E+ V+ + PSL+ I + + DG +F
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLR-----IKLLVSEKSCDGWLNFKKL 197
Query: 198 VDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGL-TFVSGLK 255
++E S T E+ E + A+Y +TSGT+GLPK A ++ + + +GL+
Sbjct: 198 LNEASTTHHCVETGSQEAS----AIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQ 252
Query: 256 ADDVIYITLPFYHSAALLIGIHGCIVAGATLA------LRTKFSASQFWDDCRKYNVTVI 309
A D+++ ++ I G ++ TL L KF Y + +
Sbjct: 253 ASDIMWT----ISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSM 308
Query: 310 QYIGELLRYLCNSPQKPNDRDHKVR-LALGNGLRGDVWRQFVKRFGDICIYEFYAATEGN 368
+ R L H LA G L + + + G + I EFY TE
Sbjct: 309 MGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTETG 367
Query: 369 IGFM-NYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVC 427
+ M + K+ + Y+ YD+ + + D+ +G++G+ V
Sbjct: 368 LTCMVSKTMKI----KPGYMGTAASCYDV--------QVIDDKGNVLPPGTEGDIGIRVK 415
Query: 428 KITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRW 487
I + F+GY + K ++ +GD + GD + D + + F R D
Sbjct: 416 PIRPIGIFSGY----VENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIINS 468
Query: 488 KGENVATTEVADTVGLVDFVQEVNVYGVHVPDH------EGRIGMASIKMKENHEFDGKK 541
G + +EV + + V E V + PD + + +AS + + E K+
Sbjct: 469 SGYRIGPSEVENALMKHPAVVETAV--ISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 526
Query: 542 LFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTL 578
L QH+ Y PR + + T T K ++ L
Sbjct: 527 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 60.8 bits (146), Expect = 3e-09
Identities = 108/513 (21%), Positives = 200/513 (38%), Gaps = 47/513 (9%)
Query: 81 YAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRA 140
+ ++ S Q A L GL++GD VA+++ P + + LG ++ G +++
Sbjct: 83 FRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 141 KSLLHCFQCCGAKVLLVSPELQAAVEEI---LPSLKKDDVSIYYVSRTSNTDGIDSFLDK 197
+L+ Q AK ++ E+ V+ + PSL+ I + + DG +F
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLR-----IKLLVSEKSCDGWLNFKKL 197
Query: 198 VDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGL-TFVSGLK 255
++E S T E+ E + A+Y +TSGT+GLPK A ++ + + +GL+
Sbjct: 198 LNEASTTHHCVETGSQEAS----AIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQ 252
Query: 256 ADDVIYITLPFYHSAALLIGIHGCIVAGAT--LALRTKFSASQFWDDCRKYNVTVIQYIG 313
A D+++ +L + GA + L KF Y + +
Sbjct: 253 ASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMGAP 312
Query: 314 ELLRYLCNSPQKPNDRDHKVR-LALGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFM 372
+ R L H + +G L + + + G + I E Y TE + M
Sbjct: 313 IVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTG-LDIRESYGQTETGLTCM 371
Query: 373 -NYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQ 431
+ K+ + Y+ YD+ + + D+ +G++G+ V I
Sbjct: 372 VSKTMKI----KPGYMGTAASCYDV--------QIIDDKGNVLPPGTEGDIGIRVKPIRP 419
Query: 432 LTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGEN 491
+ F+GY +T +GD + GD + D + + F R D G
Sbjct: 420 IGIFSGYVDNPDKTAAN------IRGDFWL-LGDRGIKDEDGYFQFMGRADDIINSSGYR 472
Query: 492 VATTEVADTVGLVDFVQEVNVYGVHVPDH------EGRIGMASIKMKENHEFDGKKLFQH 545
+ +EV + L++ V + PD + + +AS + + E K+L QH
Sbjct: 473 IGPSEVEN--ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQH 530
Query: 546 IADYLPSYARPRFLRIQDTIEITGTFKHRKMTL 578
+ Y PR + + T T K ++ L
Sbjct: 531 VKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKL 563
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 60.5 bits (145), Expect = 5e-09
Identities = 89/431 (20%), Positives = 172/431 (39%), Gaps = 47/431 (10%)
Query: 76 DETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLN 135
++ ++ ++ + S + A L D L GD + +++ P W+ L V+LG +
Sbjct: 83 EDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPGS 142
Query: 136 YNIRAKSLLHCFQCCGAKVLL----VSPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGI 191
+ AK + + + A+ ++ ++P + +AV + P+LK +
Sbjct: 143 PQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSD-CPTLK--------TKLLVSDKSY 193
Query: 192 DSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGLTFV 251
D +LD + P P+ P +T GTTG PK M+ + + G G +
Sbjct: 194 DGWLDFKKLIQVAP-PKQTYMRTKSQDPMAIFFTKGTTGAPK--MVEYSQYGLGMGFSQA 250
Query: 252 S----GLKADDVIYITLPFYHSAALLIGIHGCIVAGATLAL--RTKFSASQFWDDCRKYN 305
S L+ DV++ + + L + G GA + L F + ++
Sbjct: 251 SRRWMDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFP 310
Query: 306 VTVI----QYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIYEF 361
+T + + ELL++ C + + + K +A G + V + KR + IYE
Sbjct: 311 ITTLSANPEMYQELLQHKCFTSYR--FKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEG 367
Query: 362 YAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGE 421
Y TE + + A + L+ + L Y V+ + DEN +P GE
Sbjct: 368 YGQTETGL--------LCATSKTIKLKPSSLGKPLPPYIVQ----IVDENSNL--LPPGE 413
Query: 422 VGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRV 481
G + +I P + Y E+ +G + + +GD ++D + + ++ RV
Sbjct: 414 EGNIAIRIKLNQPASLYCPHMVSWEEY----ASARGHMLYLTGDRGIMDEDGYFWWSGRV 469
Query: 482 GDTFRWKGENV 492
D G+ +
Sbjct: 470 DDVANALGQRL 480
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 58.5 bits (140), Expect = 2e-08
Identities = 121/550 (22%), Positives = 212/550 (38%), Gaps = 64/550 (11%)
Query: 60 LEKARQTPHKPFLLFRDET-----LTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNE 114
LE+A P P + + T ++ ++ ++S + A L GL+ GD + L++
Sbjct: 66 LEEAGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRL 125
Query: 115 PAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKK 174
P + + + ++ G M + K L + Q AK ++ S L V+ I S +
Sbjct: 126 PEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAI--SAEC 183
Query: 175 DDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKA 234
+ + S+ G +F + + E STE +S P +TSGTTG PK
Sbjct: 184 PSLQTKLLVSDSSRPGWLNFRELLREASTEHNCMRTKSR----DPLAIYFTSGTTGAPK- 238
Query: 235 AMITHQRIWYGTGLTFVSG-----LKADDVIYITLP--FYHSAALLIGI---HGCIVAGA 284
M+ H + YG G SG L D+ + T + +A L CI
Sbjct: 239 -MVEHSQSSYGLGFV-ASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHE 296
Query: 285 TLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSP-QKPNDRDHKVRLALGNGLRG 343
+ A + K+ +T + + + R L + + + L G L
Sbjct: 297 L----PRVDAKVILNTLSKFPITTLCCVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNP 352
Query: 344 DVWRQFVKRFGDICIYEFYAATEGNIGFMN---YARKVGAVGRVNYLQKKIITYDLIKYD 400
DV ++ + G + +YE Y +E + N K G++G+ + YD
Sbjct: 353 DVREKWKHQTG-VELYEGYGQSETVVICANPKGMKIKSGSMGKAS-----------PPYD 400
Query: 401 VEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLY 460
V+ + D+ G +P GE G + +I PF + EK + +GD Y
Sbjct: 401 VQ----IVDDEGNV--LPPGEEGNVAVRIRPTRPFCFFNCYLDNPEKTAASE---QGDFY 451
Query: 461 FNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDH 520
+GD +D + + +F R D + EV + V E V V PD
Sbjct: 452 I-TGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAV--VSSPDP 508
Query: 521 -EGRIGMASIKMK---ENHEFDG--KKLFQHIADYLPSYARPRFLRIQDTI--EITGTFK 572
G + A I + +H+ + ++L +H+ Y PR + + ++G +
Sbjct: 509 IRGEVVKAFIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQ 568
Query: 573 HRKMTLVEEG 582
K+ E G
Sbjct: 569 RSKLRSQEWG 578
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 55.1 bits (131), Expect = 2e-07
Identities = 111/517 (21%), Positives = 196/517 (37%), Gaps = 61/517 (11%)
Query: 81 YAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRA 140
+ ++ S Q A L GL++GD VA+++ P + + LG ++ G +++
Sbjct: 83 FRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 141 KSLLHCFQCCGAKVLLVSPELQAAVEEI---LPSLKKDDVSIYYVSRTSNTDGIDSFLDK 197
+L+ Q AK ++ E+ V+ + PSL+ I + + DG +F
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLR-----IKLLVSEKSCDGWLNFKKL 197
Query: 198 VDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGL-TFVSGLK 255
++E S T E+ E + A+Y +TSGT+GLPK A ++ + + +GL+
Sbjct: 198 LNEASTTHHCVETGSQEAS----AIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQ 252
Query: 256 ADDVIYITLPFYHSAALLIGIHGCIVAGATLA------LRTKFSASQFWDDCRKYNVTVI 309
A D+++ ++ I G ++ TL L KF Y + +
Sbjct: 253 ASDIMWT----ISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSM 308
Query: 310 QYIGELLRYLCNSPQKPNDRDHKVR-LALGNGLRGDVWRQFVKRFGDICIYEFYAATEGN 368
+ R L H LA G L + + + G + I EFY TE
Sbjct: 309 MGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTETG 367
Query: 369 IGFM-NYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVC 427
+ M + K+ + Y+ YD+ P + G+ G + L C
Sbjct: 368 LTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGFA-----GTMTLSFC 418
Query: 428 KITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRW 487
G + +K +GD + GD + D + + F R D
Sbjct: 419 ------------GHQENPDKTAAN---IRGDFWL-LGDRGIKDEDGYFQFMGRADDIINS 462
Query: 488 KGENVATTEVADTVGLVDFVQEVNVYGVHVPDH------EGRIGMASIKMKENHEFDGKK 541
G + +EV + + V E V + PD + + +AS + + E K+
Sbjct: 463 SGYRIGPSEVENALMKHPAVVETAV--ISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520
Query: 542 LFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTL 578
L QH+ Y PR + + T T K ++ L
Sbjct: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 55.1 bits (131), Expect = 2e-07
Identities = 111/517 (21%), Positives = 196/517 (37%), Gaps = 61/517 (11%)
Query: 81 YAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRA 140
+ ++ S Q A L GL++GD VA+++ P + + LG ++ G +++
Sbjct: 83 FRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQMKS 142
Query: 141 KSLLHCFQCCGAKVLLVSPELQAAVEEI---LPSLKKDDVSIYYVSRTSNTDGIDSFLDK 197
+L+ Q AK ++ E+ V+ + PSL+ I + + DG +F
Sbjct: 143 TDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLR-----IKLLVSEKSCDGWLNFKKL 197
Query: 198 VDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGL-TFVSGLK 255
++E S T E+ E + A+Y +TSGT+GLPK A ++ + + +GL+
Sbjct: 198 LNEASTTHHCVETGSQEAS----AIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQ 252
Query: 256 ADDVIYITLPFYHSAALLIGIHGCIVAGATLA------LRTKFSASQFWDDCRKYNVTVI 309
A D+++ ++ I G ++ TL L KF Y + +
Sbjct: 253 ASDIMWT----ISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIKSM 308
Query: 310 QYIGELLRYLCNSPQKPNDRDHKVR-LALGNGLRGDVWRQFVKRFGDICIYEFYAATEGN 368
+ R L H LA G L + + + G + I EFY TE
Sbjct: 309 MGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTETG 367
Query: 369 IGFM-NYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVC 427
+ M + K+ + Y+ YD+ P + G+ G + L C
Sbjct: 368 LTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGFA-----GTMTLSFC 418
Query: 428 KITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRW 487
G + +K +GD + GD + D + + F R D
Sbjct: 419 ------------GHQENPDKTAAN---IRGDFWL-LGDRGIKDEDGYFQFMGRADDIINS 462
Query: 488 KGENVATTEVADTVGLVDFVQEVNVYGVHVPDH------EGRIGMASIKMKENHEFDGKK 541
G + +EV + + V E V + PD + + +AS + + E K+
Sbjct: 463 SGYRIGPSEVENALMKHPAVVETAV--ISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520
Query: 542 LFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTL 578
L QH+ Y PR + + T T K ++ L
Sbjct: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 53.1 bits (126), Expect = 7e-07
Identities = 102/515 (19%), Positives = 204/515 (39%), Gaps = 53/515 (10%)
Query: 61 EKARQTPHKPFLLF-----RDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEP 115
EKA + P P + + ++ ++ S + A L + L++GD V L++ P
Sbjct: 72 EKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVP 131
Query: 116 AYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKD 175
+ + ++ G + + K +L+ Q A ++ + L AV+ + + K +
Sbjct: 132 EWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAV--ASKCE 189
Query: 176 DVSIYYVSRTSNTDGIDSFLDKVDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKA 234
++ + ++ +G + + + S + ++ +E+ +TSGT+G PK
Sbjct: 190 NLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIM-----AIFFTSGTSGYPKM 244
Query: 235 AMITHQRIWYGTGLT----FVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALR- 289
TH +G GL+ F L DV++ T + + + + GA +
Sbjct: 245 TAHTHSS--FGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHH 302
Query: 290 -TKFSASQFWDDCRKYNVTVIQYIGELLRYLC-NSPQKPNDRDHKVRLALGNGLRGDVWR 347
+F + KY +TV + R L N + K ++ G + DV
Sbjct: 303 LPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTE 362
Query: 348 QFVKRFGDICIYEFYAATEGNI---GFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKD 404
++ + G + IYE Y TE + F K G++G+ + +DV+
Sbjct: 363 KWRNKTG-LDIYEGYGQTETVLICGNFKGMKIKPGSMGKPS-----------PAFDVK-- 408
Query: 405 EPVRDENGYCVRV-PKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNS 463
+ D NG + +G++G+ V F Y ++T +G+ Y +
Sbjct: 409 --IVDVNGNVLPPGQEGDIGIQVLPNRPFGLFTHYVDNPSKTAST------LRGNFYI-T 459
Query: 464 GDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDH-EG 522
GD +D + + +F R D G + EV + + V E V V PD G
Sbjct: 460 GDRGYMDKDGYFWFVARADDVILSSGYRIGPFEVENALNEHPSVAESAV--VSSPDPIRG 517
Query: 523 RIGMASIKMKENHE-FDGKKLFQHIADYLPSYARP 556
+ A + + +++ D ++L + I +++ P
Sbjct: 518 EVVKAFVVLNPDYKSHDQEQLIKEIQEHVKKTTAP 552
>gi|27477105 lipidosin [Homo sapiens]
Length = 724
Score = 47.8 bits (112), Expect = 3e-05
Identities = 57/220 (25%), Positives = 99/220 (45%), Gaps = 16/220 (7%)
Query: 77 ETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNY 136
E ++Y+Q + + A+ LGL+Q VA+L N P + + +G V G + +
Sbjct: 131 EHISYSQYYLLARRAAKGFLK-LGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYT 189
Query: 137 NIRAKSLLHCFQCCGAKVLLVSPELQAA----VEEILPSLKKDDVSIYYV---SRTSNTD 189
++ + C A V++V + Q + + LP LK V IY ++ +N
Sbjct: 190 TSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKA--VVIYKEPPPNKMANVY 247
Query: 190 GIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRI-W---YG 245
++ F++ +EV E + ++ L +YTSGTTG PK M++ I W YG
Sbjct: 248 TMEEFMELGNEVPEEALDAIIDTQQPNQCCVL-VYTSGTTGNPKGVMLSQDNITWTARYG 306
Query: 246 TGLTFVSGLKA-DDVIYITLPFYHSAALLIGIHGCIVAGA 284
+ + + +V+ LP H AA + + I GA
Sbjct: 307 SQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGA 346
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 45.1 bits (105), Expect = 2e-04
Identities = 84/419 (20%), Positives = 154/419 (36%), Gaps = 39/419 (9%)
Query: 158 SPELQAAVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFS 217
SP ++ + ++ LK+ + + S GID + ++ + + + W
Sbjct: 267 SPPIKRSCPDVQGKLKEKSKRVQ--PQISWNQGIDLWWHELMQEAGDECEPEWCDA---E 321
Query: 218 TPALYIYTSGTTGLPKAAMIT--HQRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIG 275
P +YTSG+TG PK + T ++ T +V A+DV + T
Sbjct: 322 DPLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYV 381
Query: 276 IHGCIVAGATLAL----RTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDH 331
+G + GAT L T ++ W KY VT +R L +P +
Sbjct: 382 TYGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHS 441
Query: 332 KVRL----ALGNGLRGDVWRQFVKRFG-DIC-IYEFYAATEGNIGFMNYARKVGAVGRVN 385
+ L +G + + W + + G C I + + TE + +
Sbjct: 442 RASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETG------GHMLTPLPGAT 495
Query: 386 YLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEV-GLLVCKITQLTPFNGYAGAKAQ 444
++ T+ + +E+G +GE G LV K P+ G
Sbjct: 496 PMKPGSATFPFFGV----APAILNESG---EELEGEAEGYLVFK----QPWPGIMRTVYG 544
Query: 445 TEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLV 504
++ FKK Y+ +GD D + + + R+ D G ++T EV +
Sbjct: 545 NHERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEH 604
Query: 505 DFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGK---KLFQHIADYLPSYARPRFLR 560
+ V E V G H +G + + + H F K +L + I + + A P +++
Sbjct: 605 EAVAEAAVVG-HPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQ 662
>gi|4758332 acyl-CoA synthetase long-chain family member 4 isoform 1
[Homo sapiens]
Length = 670
Score = 44.7 bits (104), Expect = 3e-04
Identities = 58/239 (24%), Positives = 98/239 (41%), Gaps = 17/239 (7%)
Query: 69 KPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLG 128
K +L + + Y +V+RR N L LGL+ + +A+ ++ K
Sbjct: 75 KKLILGNYKWMNYLEVNRRVNNFGSGL-TALGLKPKNTIAIFCETRAEWMIAAQTCFKYN 133
Query: 129 CAMACLNYNIRAKSLLHCFQCCGAKVLLVSPEL-QAAVEEILPSLKKDDVSIYYVSRTSN 187
+ L + ++++H A L+ S EL ++ ++ L + IY ++ N
Sbjct: 134 FPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAIN 193
Query: 188 T----DGIDSF-LDKVDEVSTEP----IPESWRSEVTFSTPALYIYTSGTTGLPKAAMIT 238
+G + + V+E+ + P IP S T S A+ +YTSG+TG PK M+
Sbjct: 194 KAEYPEGFEIHSMQSVEELGSNPENLGIPPS---RPTPSDMAIVMYTSGSTGRPKGVMMH 250
Query: 239 HQRIWYG-TG-LTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSAS 295
H + G TG + GL D LP H L I C G + + + S
Sbjct: 251 HSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SCFTYGCRIGYSSPLTLS 308
>gi|12669909 acyl-CoA synthetase long-chain family member 4 isoform
2 [Homo sapiens]
Length = 711
Score = 44.7 bits (104), Expect = 3e-04
Identities = 58/239 (24%), Positives = 98/239 (41%), Gaps = 17/239 (7%)
Query: 69 KPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLG 128
K +L + + Y +V+RR N L LGL+ + +A+ ++ K
Sbjct: 116 KKLILGNYKWMNYLEVNRRVNNFGSGL-TALGLKPKNTIAIFCETRAEWMIAAQTCFKYN 174
Query: 129 CAMACLNYNIRAKSLLHCFQCCGAKVLLVSPEL-QAAVEEILPSLKKDDVSIYYVSRTSN 187
+ L + ++++H A L+ S EL ++ ++ L + IY ++ N
Sbjct: 175 FPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAIN 234
Query: 188 T----DGIDSF-LDKVDEVSTEP----IPESWRSEVTFSTPALYIYTSGTTGLPKAAMIT 238
+G + + V+E+ + P IP S T S A+ +YTSG+TG PK M+
Sbjct: 235 KAEYPEGFEIHSMQSVEELGSNPENLGIPPS---RPTPSDMAIVMYTSGSTGRPKGVMMH 291
Query: 239 HQRIWYG-TG-LTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSAS 295
H + G TG + GL D LP H L I C G + + + S
Sbjct: 292 HSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEI-SCFTYGCRIGYSSPLTLS 349
>gi|83745141 bubblegum-related acyl-CoA synthetase 2 [Homo sapiens]
Length = 666
Score = 44.3 bits (103), Expect = 3e-04
Identities = 54/218 (24%), Positives = 89/218 (40%), Gaps = 15/218 (6%)
Query: 77 ETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNY 136
E L + Q + A++L LGL + V +L N + +G + G +
Sbjct: 79 EILNFNQYYEACRKAAKSLIK-LGLERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYA 137
Query: 137 NIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILP--SLKKDDVSIYY---VSRTSNTDGI 191
A+ + +LLV + Q +P SL+ I Y + + +N
Sbjct: 138 TNSAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLEPLKAIIQYRLPMKKNNNLYSW 197
Query: 192 DSFLD---KVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITHQRIWYGTGL 248
D F++ + + E + ES ++ A+ IYTSGTTG+PK M++H I + G
Sbjct: 198 DDFMELGRSIPDTQLEQVIESQKANQC----AVLIYTSGTTGIPKGVMLSHDNITWIAGA 253
Query: 249 TFVSGLKAD--DVIYITLPFYHSAALLIGIHGCIVAGA 284
D + + LP H AA ++ I I GA
Sbjct: 254 VTKDFKLTDKHETVVSYLPLSHIAAQMMDIWVPIKIGA 291
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 44.3 bits (103), Expect = 3e-04
Identities = 68/339 (20%), Positives = 137/339 (40%), Gaps = 26/339 (7%)
Query: 61 EKARQTPHKPFLLF-----RDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEP 115
EKA + P P + + ++ ++ S + A L + L++GD V L++ P
Sbjct: 72 EKAGKKPSNPAFWWINRNGEEMRWSFEELGSLSRKFANILSEACSLQRGDRVILILPRVP 131
Query: 116 AYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKD 175
+ + ++ G + + K +L+ Q A ++ + L AV+ + + K +
Sbjct: 132 EWWLANVACLRTGTVLIPGTTQLTQKDILYRLQSSKANCIITNDVLAPAVDAV--ASKCE 189
Query: 176 DVSIYYVSRTSNTDGIDSFLDKVDEVS-TEPIPESWRSEVTFSTPALYIYTSGTTGLPKA 234
++ + ++ +G + + + S + ++ +E+ +TSGT+G PK
Sbjct: 190 NLHSKLIVSENSREGWGNLKELMKHASDSHTCVKTKHNEIM-----AIFFTSGTSGYPKM 244
Query: 235 AMITHQRIWYGTGLT----FVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALR- 289
TH +G GL+ F L DV++ T + + + + GA +
Sbjct: 245 TAHTHSS--FGLGLSVNGRFWLDLTPSDVMWNTSDTGWAKSAWSSVFSPWIQGACVFTHH 302
Query: 290 -TKFSASQFWDDCRKYNVTVIQYIGELLRYLC-NSPQKPNDRDHKVRLALGNGLRGDVWR 347
+F + KY +TV + R L N + K ++ G + DV
Sbjct: 303 LPRFEPTSILQTLSKYPITVFCSAPTVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTE 362
Query: 348 QFVKRFGDICIYEFYAATEGNI---GFMNYARKVGAVGR 383
++ + G + IYE Y TE + F K G++G+
Sbjct: 363 KWRNKTG-LDIYEGYGQTETVLICGNFKGMKIKPGSMGK 400
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 43.1 bits (100), Expect = 8e-04
Identities = 110/533 (20%), Positives = 200/533 (37%), Gaps = 60/533 (11%)
Query: 61 EKARQTPHKPFLLF-RDET-----LTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNE 114
+ R++P L++ RDE +TY ++ + ++A L H G+ +GD VA+ M
Sbjct: 117 QHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRH-GVHRGDRVAIYMPVS 175
Query: 115 PAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPE-----LQAAVEEIL 169
P V L ++G + A+SL KV++ + +++I+
Sbjct: 176 PLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIV 235
Query: 170 PSLKKDDVSIYYVSRTSNTDG------IDSFLDKVDEVSTEPI--PESWRSEVTFSTPAL 221
K ++ +V TD +D L++ + +P+ PES SE
Sbjct: 236 DEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQ-EMAKEDPVCAPESMGSEDML----F 290
Query: 222 YIYTSGTTGLPKAAMITHQRIWYGTGLT--FVSGLKADDVIYITLPFYHSAALLIGIHGC 279
+YTSG+TG+PK + T LT V + D+ ++G
Sbjct: 291 MLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGP 350
Query: 280 IVAGATLALRTKF----SASQFWDDCRKYNVTVIQYIGE------LLRYLCNSPQKPNDR 329
+ GAT L +A ++W+ + + Q+ G LL+Y +K +
Sbjct: 351 LCNGATSVLFESTPVYPNAGRYWETVERLKIN--QFYGAPTAVRLLLKYGDAWVKKYDRS 408
Query: 330 DHKVRLALGNGLRGDVWRQFVKRFGD---ICIYEFYAATEGNIGFMNYARKVGAVGRVNY 386
+ ++G + + W + GD + ++ G I + GA
Sbjct: 409 SLRTLGSVGEPINCEAWEWLHRVVGDSRCTLVDTWWQTETGGICIAPRPSEEGA------ 462
Query: 387 LQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTE 446
+I+ ++ + DE G V V +C I+Q P G A
Sbjct: 463 ---EILPAMAMRPFFGIVPVLMDEKGSVVE--GSNVSGALC-ISQAWP--GMARTIYGDH 514
Query: 447 KKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDF 506
++ + FK Y+ +GD + R+ D G + T E+ D +
Sbjct: 515 QRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTAEIEDAIADHPA 574
Query: 507 VQEVNVYGVHVPDHEGRIGMASIKMKE---NHEFDGKKLFQHIADYLPSYARP 556
V E V G + D +G A I +K+ + + ++L +A + YA P
Sbjct: 575 VPESAVIG-YPHDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAKYAVP 626
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 42.7 bits (99), Expect = 0.001
Identities = 75/358 (20%), Positives = 131/358 (36%), Gaps = 34/358 (9%)
Query: 219 PALYIYTSGTTGLPKAAMIT--HQRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGI 276
P +YTSG+TG PK + T ++ T +V A+DV + T
Sbjct: 310 PLFILYTSGSTGKPKGVVHTVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVT 369
Query: 277 HGCIVAGATLAL----RTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHK 332
+G + GAT L T ++ W KY VT +R L +P + +
Sbjct: 370 YGPLANGATSVLFEGIPTYPDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSR 429
Query: 333 VRL----ALGNGLRGDVWRQFVKRFG-DIC-IYEFYAATEGNIGFMNYARKVGAVGRVNY 386
L +G + + W + + G C I + + TE + +
Sbjct: 430 ASLQVLGTVGEPINPEAWLWYHRVVGAQRCPIVDTFWQTETG------GHMLTPLPGATP 483
Query: 387 LQKKIITYDLIKYDVEKDEPVRDENGYCVRVPKGEV-GLLVCKITQLTPFNGYAGAKAQT 445
++ T+ + +E+G +GE G LV K P+ G
Sbjct: 484 MKPGSATFPFFGV----APAILNESG---EELEGEAEGYLVFK----QPWPGIMRTVYGN 532
Query: 446 EKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVD 505
++ FKK Y+ +GD D + + + R+ D G ++T EV + +
Sbjct: 533 HERFETTYFKKFPGYYVTGDGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHE 592
Query: 506 FVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDGK---KLFQHIADYLPSYARPRFLR 560
V E V G H +G + + + H F K +L + I + + A P +++
Sbjct: 593 AVAEAAVVG-HPHPVKGECLYCFVTLCDGHTFSPKLTEELKKQIREKIGPIATPDYIQ 649
>gi|42794754 acyl-CoA synthetase long-chain family member 3 [Homo
sapiens]
Length = 720
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/66 (43%), Positives = 37/66 (56%), Gaps = 6/66 (9%)
Query: 220 ALYIYTSGTTGLPKAAMITHQRIWYG-TGLT-FVSGLKADDVIYITLPFYH----SAALL 273
A+ +YTSG+TGLPK MI+H I G TG+ + L +DV LP H SA L+
Sbjct: 282 AVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELV 341
Query: 274 IGIHGC 279
HGC
Sbjct: 342 CLSHGC 347
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,321,556
Number of Sequences: 37866
Number of extensions: 978109
Number of successful extensions: 1923
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1852
Number of HSP's gapped (non-prelim): 58
length of query: 620
length of database: 18,247,518
effective HSP length: 108
effective length of query: 512
effective length of database: 14,157,990
effective search space: 7248890880
effective search space used: 7248890880
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.