Search of human proteins with 22748685

Search of human proteins with 22748685

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748685 clarin 3 [Homo sapiens]
         (226 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748685 clarin 3 [Homo sapiens]                                   444   e-125
gi|28144908 clarin 1 isoform a [Homo sapiens]                          80   1e-15
gi|150010645 clarin 2 [Homo sapiens]                                   69   3e-12
gi|16506281 clarin 1 isoform c [Homo sapiens]                          56   2e-08
gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 ...    29   2.9  
gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform ...    29   2.9  
gi|4758460 glycoprotein V (platelet) [Homo sapiens]                    29   2.9  
gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchan...    29   3.7  
gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]     29   3.7  
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i...    29   3.7  
gi|24119274 voltage gated channel like 1 [Homo sapiens]                28   4.9  
gi|56237029 integrin alpha 5 precursor [Homo sapiens]                  28   6.4  
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    28   6.4  
gi|55743157 WD repeat domain 33 isoform 2 [Homo sapiens]               28   6.4  
gi|19718734 toll-like receptor 2 [Homo sapiens]                        28   8.3  
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro...    28   8.3  
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro...    28   8.3  
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]          28   8.3  
gi|110665701 leucine rich repeat containing 37A [Homo sapiens]         28   8.3  

>gi|22748685 clarin 3 [Homo sapiens]
          Length = 226

 Score =  444 bits (1142), Expect = e-125
 Identities = 226/226 (100%), Positives = 226/226 (100%)

Query: 1   MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRDSASNGSIFITYGLFRGES 60
           MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRDSASNGSIFITYGLFRGES
Sbjct: 1   MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRDSASNGSIFITYGLFRGES 60

Query: 61  SEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGFTFYNSISNPY 120
           SEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGFTFYNSISNPY
Sbjct: 61  SEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGFTFYNSISNPY 120

Query: 121 QTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTSKGTTHSYGYS 180
           QTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTSKGTTHSYGYS
Sbjct: 121 QTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTSKGTTHSYGYS 180

Query: 181 FWLILLVILLNIVTVTIIIFYQKARYQRKQEQRKPMEYAPRDGILF 226
           FWLILLVILLNIVTVTIIIFYQKARYQRKQEQRKPMEYAPRDGILF
Sbjct: 181 FWLILLVILLNIVTVTIIIFYQKARYQRKQEQRKPMEYAPRDGILF 226


>gi|28144908 clarin 1 isoform a [Homo sapiens]
          Length = 232

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 51/208 (24%), Positives = 96/208 (46%), Gaps = 12/208 (5%)

Query: 1   MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRDSA----SNGSIF------ 50
           MP+ +K ++F  +   S    + + + LGT  WI +T+  +  A    ++G         
Sbjct: 1   MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGE 60

Query: 51  ITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGF 110
           + YGLF GE   +   GL     +F+    L  +   ++H   ILF  + ++ +++ + F
Sbjct: 61  MQYGLFHGEGVRQC--GLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAF 118

Query: 111 TFYNSISNPYQTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTS 170
             YN+   P++T  GP G+Y  + +  S   + MILF +  + + LSE++          
Sbjct: 119 FMYNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVY 178

Query: 171 KGTTHSYGYSFWLILLVILLNIVTVTII 198
           K  +  Y  SFW+I     ++ +   +I
Sbjct: 179 KTQSEKYTTSFWVIFFCFFVHFLNGLLI 206


>gi|150010645 clarin 2 [Homo sapiens]
          Length = 232

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 54/212 (25%), Positives = 87/212 (41%), Gaps = 12/212 (5%)

Query: 1   MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRD-----SASNGSIF----- 50
           MP   K   +  +   S  SFI+I   L    W++  I  +      +A++  +      
Sbjct: 1   MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGD 60

Query: 51  ITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGF 110
           I YGLFRG    +   GL   + +F +   L       LH + +L L L+L  +L+S GF
Sbjct: 61  IYYGLFRGCKVRQC--GLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGF 118

Query: 111 TFYNSISNPYQTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTS 170
              N I  PY+   GP G+  WN L    V + +  FVA  + + L+E +          
Sbjct: 119 AILNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQF 178

Query: 171 KGTTHSYGYSFWLILLVILLNIVTVTIIIFYQ 202
                 Y  SFW+ +     +   + ++   Q
Sbjct: 179 VVVEEQYEESFWICVASASAHAANLVVVAISQ 210


>gi|16506281 clarin 1 isoform c [Homo sapiens]
          Length = 120

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 27/96 (28%), Positives = 49/96 (51%)

Query: 88  TLHSVTILFLVLSLITSLLSSGFTFYNSISNPYQTFLGPTGVYTWNGLGASFVFVTMILF 147
           ++H   ILF  + ++ +++ + F  YN+   P++T  GP G+Y  + +  S   + MILF
Sbjct: 20  SIHVNVILFSAILIVLTMVGTAFFMYNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILF 79

Query: 148 VANTQSNQLSEELFQMLYPATTSKGTTHSYGYSFWL 183
            +  + + LSE++          K  +  Y  SFWL
Sbjct: 80  ASEVKIHHLSEKIANYKEGTYVYKTQSEKYTTSFWL 115


>gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1
           [Homo sapiens]
          Length = 854

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 30  TQAWITSTIAVRDSASNGSIFITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTL 89
           T++ +  T+  R  A+ G I          ++  LS G++   KK  + +  N  SQ   
Sbjct: 186 TRSNLDITVGSRQQATQGWI----------NTYPLSSGMSTISKKSGMSKKTNRGSQLHK 235

Query: 90  HSVTILFLVLSLITSLLSSGFTFYNSISNP 119
           + +    L+LSL+ + +    T+YN +S P
Sbjct: 236 YYMKRRTLLLSLLATEIERLITWYNPLSAP 265


>gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform 2
            [Homo sapiens]
          Length = 2044

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 30   TQAWITSTIAVRDSASNGSIFITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTL 89
            T++ +  T+  R  A+ G I          ++  LS G++   KK  + +  N  SQ   
Sbjct: 1376 TRSNLDITVGSRQQATQGWI----------NTYPLSSGMSTISKKSGMSKKTNRGSQLHK 1425

Query: 90   HSVTILFLVLSLITSLLSSGFTFYNSISNP 119
            + +    L+LSL+ + +    T+YN +S P
Sbjct: 1426 YYMKRRTLLLSLLATEIERLITWYNPLSAP 1455


>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
          Length = 560

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 15/53 (28%), Positives = 24/53 (45%)

Query: 157 SEELFQMLYPATTSKGTTHSYGYSFWLILLVILLNIVTVTIIIFYQKARYQRK 209
           S E +    P TT KG  HS  + F+ +LL +   I  + +    +  +  RK
Sbjct: 500 SSEPWVWAQPVTTGKGQDHSPFWGFYFLLLAVQAMITVIIVFAMIKIGQLFRK 552


>gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchange
           factor 2, partial [Homo sapiens]
          Length = 803

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 20/64 (31%), Positives = 32/64 (50%)

Query: 42  DSASNGSIFITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSL 101
           DS  +GS     GL RG+   E++    E  +    +EIL N++  ++   T LF+   L
Sbjct: 414 DSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKEL 473

Query: 102 ITSL 105
           +T L
Sbjct: 474 LTRL 477


>gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]
          Length = 1499

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 20/64 (31%), Positives = 32/64 (50%)

Query: 42  DSASNGSIFITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSL 101
           DS  +GS     GL RG+   E++    E  +    +EIL N++  ++   T LF+   L
Sbjct: 414 DSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKEL 473

Query: 102 ITSL 105
           +T L
Sbjct: 474 LTRL 477


>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
           isoform a [Homo sapiens]
          Length = 214

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 7/113 (6%)

Query: 14  FFTSLGSFIVICSILGTQAWITST----IAVRDSASNGSIFITYGLFRGESSEELSHGLA 69
           FF S G+  V+  I  T+ WI ++    IA    A  G+ F++  +     S    H  +
Sbjct: 98  FFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSCHSSS 157

Query: 70  EPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGFTFYNS---ISNP 119
           E       +  ++N     L  +T+L L +++ T  +       NS   IS+P
Sbjct: 158 ESPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAMWCNANCCNSREEISSP 210


>gi|24119274 voltage gated channel like 1 [Homo sapiens]
          Length = 1738

 Score = 28.5 bits (62), Expect = 4.9
 Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 12/132 (9%)

Query: 21  FIVICSILGTQAWITSTI--AVRDSASNGSIFITYGLFRGESSEELSHGL-AEPKKKFAV 77
           F+++  ILG Q + T T    V D+      + +  +     S EL  G    P  K   
Sbjct: 188 FLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMD 247

Query: 78  LEILNNSSQKTLHSVTILFLVLSLITSLLSSGFTFYNSISNPYQTFLGPTGVYTWNGLGA 137
           LE L  S Q+         L  S    + +S FT Y + S     FL    + ++    +
Sbjct: 248 LEDLGLSRQE---------LGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRS 298

Query: 138 SFVFVTMILFVA 149
            F F+T+I F+A
Sbjct: 299 YFYFITLIFFLA 310


>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
          Length = 1049

 Score = 28.1 bits (61), Expect = 6.4
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 2/46 (4%)

Query: 176  SYGYSFWLILLVILLNIVTVTIIIF--YQKARYQRKQEQRKPMEYA 219
            SYG   W+I+L IL  ++ + ++I+  Y+   ++R       ME A
Sbjct: 994  SYGVPLWIIILAILFGLLLLGLLIYILYKLGFFKRSLPYGTAMEKA 1039


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
           [Homo sapiens]
          Length = 1336

 Score = 28.1 bits (61), Expect = 6.4
 Identities = 18/84 (21%), Positives = 32/84 (38%), Gaps = 15/84 (17%)

Query: 132 WNGLGASFVFVTMILFVANTQSNQLSEELFQMLYP---------ATTSKGTT------HS 176
           WNG+     +    + + +   N+   E+     P            S GT         
Sbjct: 521 WNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEP 580

Query: 177 YGYSFWLILLVILLNIVTVTIIIF 200
           Y  + W+++ V+ L +V VT+ IF
Sbjct: 581 YSPAVWVMMFVMCLTVVAVTVFIF 604


>gi|55743157 WD repeat domain 33 isoform 2 [Homo sapiens]
          Length = 326

 Score = 28.1 bits (61), Expect = 6.4
 Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 4/95 (4%)

Query: 101 LITSLLSSGFTFYNSISNPYQTFL----GPTGVYTWNGLGASFVFVTMILFVANTQSNQL 156
           L+T   S  FT +N ++  ++T L     P    TW+      +      +V   QSN  
Sbjct: 134 LVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSNMN 193

Query: 157 SEELFQMLYPATTSKGTTHSYGYSFWLILLVILLN 191
           + ++FQ    A       H+  +S   I++V L +
Sbjct: 194 NVKMFQAHKEAIREARFIHNIPFSVVPIVMVKLFS 228


>gi|19718734 toll-like receptor 2 [Homo sapiens]
          Length = 784

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 7/60 (11%)

Query: 78  LEILNNSSQKTLHSVTILFLVLSLITSLLSSGF------TFYNSISNPYQTFLGPTGVYT 131
           +  +   S  +L S+  L L  + +++L SS F      TF N + NPY+T LG T +++
Sbjct: 88  INTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPYKT-LGETSLFS 146


>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 1 [Homo sapiens]
          Length = 1635

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 15/47 (31%), Positives = 25/47 (53%)

Query: 154  NQLSEELFQMLYPATTSKGTTHSYGYSFWLILLVILLNIVTVTIIIF 200
            N+ +E   +    +   K     YGY+  LIL +I+  I+T+ II+F
Sbjct: 1553 NESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILF 1599


>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 2 [Homo sapiens]
          Length = 1700

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 15/47 (31%), Positives = 25/47 (53%)

Query: 154  NQLSEELFQMLYPATTSKGTTHSYGYSFWLILLVILLNIVTVTIIIF 200
            N+ +E   +    +   K     YGY+  LIL +I+  I+T+ II+F
Sbjct: 1553 NESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILF 1599


>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
          Length = 1700

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 15/47 (31%), Positives = 25/47 (53%)

Query: 154  NQLSEELFQMLYPATTSKGTTHSYGYSFWLILLVILLNIVTVTIIIF 200
            N+ +E   +    +   K     YGY+  LIL +I+  I+T+ II+F
Sbjct: 1553 NESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILF 1599


>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
          Length = 1700

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 15/47 (31%), Positives = 25/47 (53%)

Query: 154  NQLSEELFQMLYPATTSKGTTHSYGYSFWLILLVILLNIVTVTIIIF 200
            N+ +E   +    +   K     YGY+  LIL +I+  I+T+ II+F
Sbjct: 1553 NESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILF 1599


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,378,989
Number of Sequences: 37866
Number of extensions: 263807
Number of successful extensions: 805
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 787
Number of HSP's gapped (non-prelim): 23
length of query: 226
length of database: 18,247,518
effective HSP length: 99
effective length of query: 127
effective length of database: 14,498,784
effective search space: 1841345568
effective search space used: 1841345568
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.