Search of human proteins with 227430301

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
         (1428 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]        2835   0.0  
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]        2825   0.0  
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]        2499   0.0  
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]               514   e-145
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]            493   e-139
gi|162809334 pregnancy-zone protein [Homo sapiens]                    485   e-136
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]                    372   e-102
gi|169204289 PREDICTED: ovostatin [Homo sapiens]                      360   5e-99
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta...   315   2e-85
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s...   229   1e-59
gi|115298678 complement component 3 precursor [Homo sapiens]          216   2e-55
gi|178557739 complement component 4B preproprotein [Homo sapiens]     208   3e-53
gi|67190748 complement component 4A preproprotein [Homo sapiens]      208   3e-53
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s...   208   3e-53
gi|38016947 complement component 5 preproprotein [Homo sapiens]       181   4e-45
gi|169218213 PREDICTED: similar to complement component C3, part...   180   1e-44
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]         177   5e-44
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...    87   9e-17
gi|239758130 PREDICTED: similar to complement component 4B (Chil...    87   1e-16
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg...    72   3e-12
gi|169214179 PREDICTED: similar to complement component 3 [Homo ...    50   2e-05
gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...    47   2e-04
gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...    47   2e-04
gi|239755748 PREDICTED: ovostatin [Homo sapiens]                       45   4e-04
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H...    35   0.67 
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H...    35   0.67 
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]            33   2.0  
gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]             33   2.6  
gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sap...    33   2.6  
gi|89264696 angiopoietin-like 4 protein isoform b precursor [Hom...    32   4.4  

>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
          Length = 1428

 Score = 2835 bits (7350), Expect = 0.0
 Identities = 1428/1428 (100%), Positives = 1428/1428 (100%)

Query: 1    MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
            MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA
Sbjct: 1    MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60

Query: 61   ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST 120
            ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST
Sbjct: 61   ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST 120

Query: 121  RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL 180
            RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL
Sbjct: 121  RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL 180

Query: 181  SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS 240
            SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS
Sbjct: 181  SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS 240

Query: 241  MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK 300
            MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK
Sbjct: 241  MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK 300

Query: 301  NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
            NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL
Sbjct: 301  NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360

Query: 361  KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
            KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY
Sbjct: 361  KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420

Query: 421  TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
            TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG
Sbjct: 421  TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480

Query: 481  SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG 540
            SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG
Sbjct: 481  SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG 540

Query: 541  EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN 600
            EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN
Sbjct: 541  EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN 600

Query: 601  ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY 660
            ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY
Sbjct: 601  ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY 660

Query: 661  AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW 720
            AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW
Sbjct: 661  AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW 720

Query: 721  VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV 780
            VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV
Sbjct: 721  VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV 780

Query: 781  KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT 840
            KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT
Sbjct: 781  KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT 840

Query: 841  ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI 900
            ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI
Sbjct: 841  ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI 900

Query: 901  GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG 960
            GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG
Sbjct: 901  GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG 960

Query: 961  YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH 1020
            YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH
Sbjct: 961  YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH 1020

Query: 1021 QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS 1080
            QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS
Sbjct: 1021 QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS 1080

Query: 1081 RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL 1140
            RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL
Sbjct: 1081 RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL 1140

Query: 1141 DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT 1200
            DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT
Sbjct: 1141 DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT 1200

Query: 1201 ERTNIQVTVTGPSSPSPLAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQN 1260
            ERTNIQVTVTGPSSPSPLAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQN
Sbjct: 1201 ERTNIQVTVTGPSSPSPLAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQN 1260

Query: 1261 QEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSGFMVPSEAISLSETV 1320
            QEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSGFMVPSEAISLSETV
Sbjct: 1261 QEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSGFMVPSEAISLSETV 1320

Query: 1321 KKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNS 1380
            KKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNS
Sbjct: 1321 KKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNS 1380

Query: 1381 EVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYFMELWL 1428
            EVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYFMELWL
Sbjct: 1381 EVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYFMELWL 1428


>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
          Length = 1445

 Score = 2825 bits (7322), Expect = 0.0
 Identities = 1428/1445 (98%), Positives = 1428/1445 (98%), Gaps = 17/1445 (1%)

Query: 1    MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
            MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA
Sbjct: 1    MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60

Query: 61   ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST 120
            ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST
Sbjct: 61   ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNST 120

Query: 121  RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL 180
            RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL
Sbjct: 121  RLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWL 180

Query: 181  SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS 240
            SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS
Sbjct: 181  SQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCS 240

Query: 241  MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK 300
            MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK
Sbjct: 241  MNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMK 300

Query: 301  NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
            NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL
Sbjct: 301  NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360

Query: 361  KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
            KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY
Sbjct: 361  KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420

Query: 421  TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
            TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG
Sbjct: 421  TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480

Query: 481  SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG 540
            SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG
Sbjct: 481  SPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDG 540

Query: 541  EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN 600
            EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN
Sbjct: 541  EIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMN 600

Query: 601  ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY 660
            ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY
Sbjct: 601  ASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEY 660

Query: 661  AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW 720
            AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW
Sbjct: 661  AERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSW 720

Query: 721  VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV 780
            VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV
Sbjct: 721  VATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEV 780

Query: 781  KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT 840
            KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT
Sbjct: 781  KVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPT 840

Query: 841  ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI 900
            ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI
Sbjct: 841  ASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAI 900

Query: 901  GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG 960
            GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG
Sbjct: 901  GDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQG 960

Query: 961  YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH 1020
            YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH
Sbjct: 961  YQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGH 1020

Query: 1021 QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS 1080
            QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS
Sbjct: 1021 QKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFS 1080

Query: 1081 RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL 1140
            RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL
Sbjct: 1081 RGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSL 1140

Query: 1141 DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT 1200
            DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT
Sbjct: 1141 DIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNT 1200

Query: 1201 ERTNIQVTVTGPSSPSP-----------------LAVVQPTAVNISANGFGFAICQLNVV 1243
            ERTNIQVTVTGPSSPSP                 LAVVQPTAVNISANGFGFAICQLNVV
Sbjct: 1201 ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1260

Query: 1244 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL 1303
            YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL
Sbjct: 1261 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL 1320

Query: 1304 LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVS 1363
            LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVS
Sbjct: 1321 LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVS 1380

Query: 1364 IVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYF 1423
            IVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYF
Sbjct: 1381 IVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYF 1440

Query: 1424 MELWL 1428
            MELWL
Sbjct: 1441 MELWL 1445


>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
          Length = 1368

 Score = 2499 bits (6476), Expect = 0.0
 Identities = 1260/1279 (98%), Positives = 1260/1279 (98%), Gaps = 17/1279 (1%)

Query: 167  LIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL 226
            L  DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL
Sbjct: 90   LPSDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVL 149

Query: 227  PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI 286
            PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI
Sbjct: 150  PKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKI 209

Query: 287  NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ 346
            NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ
Sbjct: 210  NGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQ 269

Query: 347  HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN 406
            HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN
Sbjct: 270  HDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSN 329

Query: 407  SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT 466
            SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT
Sbjct: 330  SGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKT 389

Query: 467  YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT 526
            YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT
Sbjct: 390  YIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWT 449

Query: 527  PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI 586
            PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI
Sbjct: 450  PKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSI 509

Query: 587  VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL 646
            VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL
Sbjct: 510  VGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANL 569

Query: 647  TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY 706
            TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY
Sbjct: 570  TKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIY 629

Query: 707  QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL 766
            QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL
Sbjct: 630  QEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFAL 689

Query: 767  EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH 826
            EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH
Sbjct: 690  EITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTH 749

Query: 827  LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP 886
            LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP
Sbjct: 750  LGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPP 809

Query: 887  NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT 946
            NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT
Sbjct: 810  NTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLT 869

Query: 947  DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID 1006
            DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID
Sbjct: 870  DNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDID 929

Query: 1007 QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI 1066
            QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI
Sbjct: 930  QNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNI 989

Query: 1067 DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS 1126
            DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS
Sbjct: 990  DVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVS 1049

Query: 1127 SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV 1186
            SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV
Sbjct: 1050 SESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTV 1109

Query: 1187 ALKALSEFAALMNTERTNIQVTVTGPSSPSP-----------------LAVVQPTAVNIS 1229
            ALKALSEFAALMNTERTNIQVTVTGPSSPSP                 LAVVQPTAVNIS
Sbjct: 1110 ALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNIS 1169

Query: 1230 ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS 1289
            ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS
Sbjct: 1170 ANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFS 1229

Query: 1290 GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV 1349
            GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV
Sbjct: 1230 GPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAV 1289

Query: 1350 RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH 1409
            RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH
Sbjct: 1290 RNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHH 1349

Query: 1410 SSVIFIFCFKLLYFMELWL 1428
            SSVIFIFCFKLLYFMELWL
Sbjct: 1350 SSVIFIFCFKLLYFMELWL 1368



 Score =  184 bits (468), Expect = 4e-46
 Identities = 93/94 (98%), Positives = 93/94 (98%)

Query: 1  MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60
          MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA
Sbjct: 1  MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKA 60

Query: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLP 94
          ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPS P
Sbjct: 61 ELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSDP 94


>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
          Length = 1454

 Score =  514 bits (1325), Expect = e-145
 Identities = 415/1497 (27%), Positives = 704/1497 (47%), Gaps = 193/1497 (12%)

Query: 20   LAVAPG-----PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVL 74
            LA++P      P +LVT P  +       + ++L    P    VK  +     + T  +L
Sbjct: 10   LALSPAIAEELPNYLVTLPARLNFPSVQKVCLDL---SPGYSDVKFTVTLETKDKTQKLL 66

Query: 75   EAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQ 134
            E  G+ ++       L   P    +E+  +RV+G   + I F    ++  + +    F+Q
Sbjct: 67   EYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSG-VGNNISFEEKKKVLIQRQGNGTFVQ 125

Query: 135  TDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGVISKTF 193
            TDK LY P Q+V FRIVT+ S+F P     +++ ++DP SN I QWL    + G++  +F
Sbjct: 126  TDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLSF 185

Query: 194  QLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAK 253
            QL+   +LG +++ V   +   + +F V EYVLPKF+V +  P   S   +     I  +
Sbjct: 186  QLAPEAMLGTYTVAVA--EGKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKICCR 243

Query: 254  YTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYL 313
            YTYGKP+ G V ++         +K  T  ++             +    D +   S  +
Sbjct: 244  YTYGKPMLGAVQVSVC-------QKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPV 296

Query: 314  DLSS--------PGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLN 365
            D+++           + I+ TV E  TG+  N + N++       + F D +    P+  
Sbjct: 297  DMATFDLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFP 356

Query: 366  FTATVKVTRADGNQLTLEERRNNVVITV---TQRNYTEYWSGSNSGNQK--MEAVQKINY 420
            F+  ++V   D + L     +N++V  V   T   + +     N+G     +E       
Sbjct: 357  FSGKIRVRGHDDSFL-----KNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGT 411

Query: 421  TVPQSGTFKIE--------FPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKT 472
             V   G F++E         P    ++ L L+ ++  ++S + +H L             
Sbjct: 412  DVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRL------------- 458

Query: 473  RDENIKVGSPFELVV---------SGNKRLKELSYMVVSRGQLVAVGKQN---------- 513
             +  +K G P E++V         S ++ +   SY ++ +G LV  G+++          
Sbjct: 459  -NGPLKCGQPQEVLVDYYIDPADASPDQEIS-FSYYLIGKGSLVMEGQKHLNSKKKGLKA 516

Query: 514  STMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEK 573
            S   SLT  +   P   +++Y I   G +++D ++  V++ F N++ L +S  +  P  +
Sbjct: 517  SFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAE 576

Query: 574  VSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVV-----------HELELYNTGYY 622
            V L++    P S+  + AVD+SV L+    +++  +V            +++  Y+    
Sbjct: 577  VELQLQAA-PGSLCALRAVDESVLLLRPDRELSNRSVYGMFPFWYGHYPYQVAEYDQCPV 635

Query: 623  LGMF-----------------------------MNSFAVFQECGLWVLTDANLTKDYIDG 653
             G +                              + F+ F++ GL +L++A + K  +D 
Sbjct: 636  SGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEGTDLFSFFRDVGLKILSNAKIKKP-VDC 694

Query: 654  VYDNAEYAERFMEENEGHIVDIHDFS---LGSSPHVRKHFPETWIWLDTNMGYRIYQEFE 710
             + + EY+   M    GH       +         VR++FPETW+W    +G    +   
Sbjct: 695  SHRSPEYSTA-MGAGGGHPEAFESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVH 753

Query: 711  VTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITI 770
            VTVPD+IT W A  F  S+  G GL+ T V L AF+PFF+ L LPYSV+RGE F L  TI
Sbjct: 754  VTVPDAITEWKAMSFCTSQSRGFGLSPT-VGLTAFKPFFVDLTLPYSVVRGESFRLTATI 812

Query: 771  FNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEI 830
            FNYLKD   V+  + KS ++ +   ++       Q +  + +++  T  + I    LG I
Sbjct: 813  FNYLKDCIRVQTDLAKSHEYQLESWADS------QTSSCLCADEAKTHHWNITAVKLGHI 866

Query: 831  PITVTAL----------------SPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQ 874
              T++                      SD + + +LVK EG+    + S LL     ++ 
Sbjct: 867  NFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKPVLVKPEGVLVEKTHSSLL-CPKGKVA 925

Query: 875  STLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIY 934
            S  +++S   P + V  S +  +T +GD++G ++  L  L++MP GCGEQNM+ FAP IY
Sbjct: 926  S--ESVSLELPVDIVPDSTKAYVTVLGDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIY 983

Query: 935  ILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLR 994
            +L YL K   LT+ ++ +A+ F+  GYQ+EL+Y+  +GS+SAFG  D +G+TWL+AFV +
Sbjct: 984  VLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTK 1043

Query: 995  CFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVT 1054
            CF +A  +I ID   +     W+ G+Q  +G + + G ++H+ ++GG    V+LTAY+  
Sbjct: 1044 CFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTA 1103

Query: 1055 SLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKE-ALNMLTW 1113
            +LL   K   +  V + +  L++  +   ++ YT AL+ Y  S  G    +   L  L  
Sbjct: 1104 ALLEMGKDVDDPMVSQGLRCLKNS-ATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQ 1162

Query: 1114 RAEQEGGMQFWVSSESKLSDS--W-QPRSLDIEVAAYALLSH-----FLQFQTSEGIPIM 1165
            +A   G   +W    +  S++  W +P ++D+E+ AYALL+        Q + ++   I+
Sbjct: 1163 QAIISGESIYWSQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATSIV 1222

Query: 1166 RWLSRQRNSLGGFASTQDTTVALKALSEFA--ALMNTERTNIQVTVT-------GPSSPS 1216
             WL++QRN+ GGF+STQDT VAL+AL+++A  A M +E  N+ V  T          S +
Sbjct: 1223 AWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINLVVKSTENFQRTFNIQSVN 1282

Query: 1217 PLAVVQPTAVNI------SANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV 1270
             L   Q T  N+       A+G G    Q  + YN+             N + F L V +
Sbjct: 1283 RLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPP---------TNMKTFSLSVEI 1333

Query: 1271 K----ENKDDLNHVDLNVCTSFSGP-GRSGMALMEVNLLSGF--MVPSEAISLSE-TVKK 1322
                 E       + L + TS+ G    S MA++EV +LSGF  M  +  + L +  VKK
Sbjct: 1334 GKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQPLVKK 1393

Query: 1323 VEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYN 1379
            VE+    LN+YLD + +          ++  V+N + A++ + DYY P  QA   Y+
Sbjct: 1394 VEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYS 1450


>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
          Length = 1474

 Score =  493 bits (1269), Expect = e-139
 Identities = 425/1507 (28%), Positives = 696/1507 (46%), Gaps = 194/1507 (12%)

Query: 12   LLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTV 71
            LL +     +V+  P+++V  P ++        G  LL +    VTV A L     N ++
Sbjct: 15   LLVLLPTDASVSGKPQYMVLVPSLLHTE-TTEKGCVLLSYLNETVTVSASLESVRGNRSL 73

Query: 72   SV-LEAEG-VFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRI 129
               LEAE  V    +F    +P    N       ++V G TQ+   F   T +  + +  
Sbjct: 74   FTDLEAENDVLHCVAF---AVPKSSSNEEVMFLTVQVKGPTQE---FKKRTTVMVKNEDS 127

Query: 130  SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGV 188
             VF+QTDK++YKP Q VKFR+V++  +F P    + ++ I+DPK N I QW S Q + G+
Sbjct: 128  LVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGL 187

Query: 189  ISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPKFEVTLQTPLYCSMNSKHLN 247
               +F LSS P  G + + VQ       +  F V E+VLPKFEV +  P   ++  + +N
Sbjct: 188  KQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMN 247

Query: 248  GTITAKYTYGKPVKGDVTLT----FLPLSFWGKKKNITKTFKINGSANFS--FNDEEMKN 301
             ++   YTYGKPV G VT++    +   S    + +     K +G  N    F  +    
Sbjct: 248  VSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTK 307

Query: 302  VMDSSNGLSEY-LDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
            V        EY + L +   ++   TV E +TG   +  T    K     + F    +  
Sbjct: 308  VFQLKR--KEYEMKLHTEAQIQEEGTVVE-LTGRQSSEITRTITK-----LSFVKVDSHF 359

Query: 361  KPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
            +  + F   V++    G  +       N VI + + N   Y+S + +    +     IN 
Sbjct: 360  RQGIPFFGQVRLVDGKGVPIP------NKVIFI-RGNEANYYSNATTDEHGLVQFS-INT 411

Query: 421  T--VPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SPSKTYIQLKTRDEN 476
            T  +  S T ++ +         Q    ++  +   A H+ +   SPSK+++ L+     
Sbjct: 412  TNVMGTSLTVRVNYKDRSPCYGYQ----WVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHE 467

Query: 477  IKVGSPFEL----VVSGNKRL--KELS--YMVVSRGQLVAVGKQNSTM----------FS 518
            +  G    +    +++G   L  K+LS  Y+++++G +V  G     +           S
Sbjct: 468  LPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSIS 527

Query: 519  LTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRI 578
            +  ++   P A +++Y +   G++I D  K  V+    NK+ L +S  ++ P+    LR+
Sbjct: 528  IPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRV 587

Query: 579  SVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLG-------------- 624
            +   P S+  + AVD+SV LM    +++  +V + L   +   + G              
Sbjct: 588  TAA-PQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRH 646

Query: 625  -MFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNAE---------- 659
             +++N               ++  ++ GL   T++ + K  +       E          
Sbjct: 647  NVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVG 706

Query: 660  -YAERFMEENEGHIVDIHDFSLGSSPH---VRKHFPETWIWLDTNMGYRIYQEFEVTVPD 715
             Y    M      +V + +      PH   VRK+FPETWIW    +      E  VTVPD
Sbjct: 707  FYESDVMGRGHARLVHVEE------PHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPD 760

Query: 716  SITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLK 775
            +IT W A  F +SED GLG+++T   L+AFQPFF+ L +PYSVIRGE F L+ T+ NYL 
Sbjct: 761  TITEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLP 819

Query: 776  DATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVT 835
                V V +E S  F  +    E      Q    + +    TV + + P  LG +  TV+
Sbjct: 820  KCIRVSVQLEASPAFLAVPVEKE------QAPHCICANGRQTVSWAVTPKSLGNVNFTVS 873

Query: 836  ALSPTAS----------------DAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKT 879
            A +  +                 D V + +LV+ EG+EK  + + LL  +   +    + 
Sbjct: 874  AEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVS---EE 930

Query: 880  LSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYL 939
            LS   PPN V  S R  ++ +GD+LG ++    +L++MPYGCGEQNM+ FAPNIY+LDYL
Sbjct: 931  LSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYL 990

Query: 940  TKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY--DPSGSTWLSAFVLRCFL 997
             + +QLT  +K KA+ ++  GYQR+L Y+  DGS+S FG       G+TWL+AFVL+ F 
Sbjct: 991  NETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFA 1050

Query: 998  EADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLL 1057
            +A  YI ID+  + +   WL   QK NG F   G ++++ ++GG +  VTL+AYI  +LL
Sbjct: 1051 QARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALL 1110

Query: 1058 GYRKYQPNIDVQESIHFLESEFSRGI-----SDNYTLALITYALSSVGS-PKAKEALNML 1111
                   +  V+ ++  LES +         S  YT AL+ YA +  G+  K KE L  L
Sbjct: 1111 EIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSL 1170

Query: 1112 TWRAEQEGGMQFW---VSSESKLSDSWQPR--SLDIEVAAYALLSHFL--QFQTSEGIP- 1163
               A ++     W      ++ +   ++P+  S ++E+ +Y LL++       TSE +  
Sbjct: 1171 NEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTS 1230

Query: 1164 ---IMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPLAV 1220
               I++W+++Q+N+ GGF+STQDT VAL ALS++ A   T RT     VT  SS +  + 
Sbjct: 1231 ATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFT-RTGKAAQVTIQSSGTFSSK 1289

Query: 1221 VQ-----------------PTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEA 1263
             Q                 P   ++   G G    Q ++ YN+           +  +E 
Sbjct: 1290 FQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNI-----------LPEKEE 1338

Query: 1264 FDLDVAVKENKDDLN----HVDLNVCTSFSGPG---RSGMALMEVNLLSGFMVPSEAISL 1316
            F   + V+      +    H    +  S S  G    S MA+++V ++SGF+     + +
Sbjct: 1339 FPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKM 1398

Query: 1317 ---SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQ 1373
               S  V + E     + +YLD V+     +    +++  V + + A V + DYYE    
Sbjct: 1399 LERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEF 1458

Query: 1374 AVRSYNS 1380
            A+  YN+
Sbjct: 1459 AIAEYNA 1465


>gi|162809334 pregnancy-zone protein [Homo sapiens]
          Length = 1482

 Score =  485 bits (1248), Expect = e-136
 Identities = 420/1502 (27%), Positives = 695/1502 (46%), Gaps = 181/1502 (12%)

Query: 12   LLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTV 71
            LL + +A+ + +  P+++V  P ++        G  LL H    VTV A L     N + 
Sbjct: 14   LLILLSASDSNSTEPQYMVLVPSLLHTEAPKK-GCVLLSHLNETVTVSASLESGRENRS- 71

Query: 72   SVLEAEGVFEKGSFK--TLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRI 129
              L  + V EK  F   + TLP +  +S      +++ G TQD      +T L   T+ +
Sbjct: 72   --LFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQD--FRKRNTVLVLNTQSL 127

Query: 130  SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGV 188
             VF+QTDK +YKP Q V+FR+V++  +F+P    + ++ +++P+ N I QW S + + G+
Sbjct: 128  -VFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAGI 186

Query: 189  ISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPKFEVTLQTPLYCSMNSKHLN 247
               +F LSS PI G + + VQ       Q  F V E+VLPKFEV +Q P   S+  + +N
Sbjct: 187  NQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVN 246

Query: 248  GTITAKYTYGKPVKGDVTLTF---LPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMD 304
             T+  +YTYGKPV G  T++    L       K+ + + F    ++N     +    ++ 
Sbjct: 247  ITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQLNSNGCITQQVHTKMLQ 306

Query: 305  SSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSL 364
             +N   E + L     +    T  E VT    +  TN+  K     ++F    +  +  +
Sbjct: 307  ITNTGFE-MKLRVEARIREEGTDLE-VTANRISEITNIVSK-----LKFVKVDSHFRQGI 359

Query: 365  NFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQ 424
             F A V +   DG  + +  +   + +     N   Y+S + +  Q + A   IN T   
Sbjct: 360  PFFAQVLLV--DGKGVPIPNKLFFISV-----NDANYYSNATTNEQGL-AQFSINTT--S 409

Query: 425  SGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SPSKTYIQLKTRDENIKVG-- 480
                K+   +      L     ++      A H+  +  S S +YI L+     +  G  
Sbjct: 410  ISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHT 469

Query: 481  ----SPFELVVSGNKRLKELS--YMVVSRGQLVAVGK----------QNSTMFSLTPENS 524
                + + L       L ELS  Y+++++G +V  G           + S   S   E+ 
Sbjct: 470  ETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESD 529

Query: 525  WTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPD 584
              P A + ++ I  DGE++ D  K  ++    NK+ L +S  ++ P+    L+++   P 
Sbjct: 530  VAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAA-PQ 588

Query: 585  SIVGIVAVDKSVNLMNASNDITMENVVHELE--------------------------LYN 618
            S+  + AVD+SV LM    ++++ +V + L                           ++N
Sbjct: 589  SLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHN 648

Query: 619  TGYYLGMFMNS---FAVFQECGLWVLTDANLTK--------DYIDGVYDNAEYAERFMEE 667
               Y+ +  N    ++  +  GL V T++ + K            G      Y       
Sbjct: 649  GAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVV 708

Query: 668  NEGHIVDIHDFSL---------GSSPH-VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSI 717
               ++  +  +++         G  P  VR +FPETWIW    +      E  VTVPD+I
Sbjct: 709  ERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTI 768

Query: 718  TSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDA 777
            T W A  F +SED GLG+++T   L+AFQPFF+ L +PYSVIRGE F L+ T+ NYL   
Sbjct: 769  TEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKC 827

Query: 778  TEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTAL 837
              V V ++ S  F  L + N    T  +++  +   +  T+ + + P  LG +  +V+A 
Sbjct: 828  IRVSVQLKASPAF--LASQN----TKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAE 881

Query: 838  SPTA----------------SDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLS 881
            +  +                 D V + +LV+AEGIE+  + S    +T     +  + LS
Sbjct: 882  AMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTFS---SMTCASGANVSEQLS 938

Query: 882  FSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTK 941
               P N V  S R   + +GD+LG ++  + +L++MPYGCGEQNM+ FAPNIY+L+YL +
Sbjct: 939  LKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNE 998

Query: 942  KKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY--DPSGSTWLSAFVLRCFLEA 999
             +QLT  +K KA+ ++  GYQR+L Y+ +DGS+S FG       G+TWL+AFVL+ F +A
Sbjct: 999  TQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQA 1058

Query: 1000 DPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGY 1059
              YI ID+  + ++ TWL   QK NG F   G ++++ ++GG +   TL+AY+  +LL  
Sbjct: 1059 RSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEI 1118

Query: 1060 RKYQPNIDVQESIHFLES------EFSRGISDNYTLALITYALSSVGSP-KAKEALNMLT 1112
                 N  V+ ++  LES      E + G S  YT AL+ YA S +G   + +E LN L 
Sbjct: 1119 PLPVTNPIVRNALFCLESAWNVAKEGTHG-SHVYTKALLAYAFSLLGKQNQNREILNSLD 1177

Query: 1113 WRAEQEGGMQFWVSSESKLSD-----SWQPRSLDIEVAAYALLSHF------LQFQTSEG 1161
              A +E  +  W   +   +        Q  S ++E+ +Y LL++            +  
Sbjct: 1178 KEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSA 1237

Query: 1162 IPIMRWLSRQRNSLGGFASTQDTTVALKALSEF--AALMNTERTNIQVTVTGPSSPSP-- 1217
              I++W+ +Q+N+ GGF+STQDT VAL ALS +  A    TE+T  QVTV    + S   
Sbjct: 1238 TNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKT-AQVTVQDSQTFSTNF 1296

Query: 1218 ------LAVVQ-------PTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAF 1264
                  L ++Q       P    I+  G      Q ++ YN+            +    F
Sbjct: 1297 QVDNNNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNILPE---------KEDSPF 1347

Query: 1265 DLDVAVKENKDDLN--HVDLNVCTSFSGPGR---SGMALMEVNLLSGFMVPSEAISL--- 1316
             L V       D +  H    +  + S  G    S M +++V ++SGF+     + +   
Sbjct: 1348 ALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLER 1407

Query: 1317 SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVR 1376
            S +V + E  +  + +Y++ V       +   +++  V + + A V + DYYE     V 
Sbjct: 1408 SSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVA 1467

Query: 1377 SY 1378
             Y
Sbjct: 1468 EY 1469


>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
          Length = 1394

 Score =  372 bits (955), Expect = e-102
 Identities = 354/1340 (26%), Positives = 585/1340 (43%), Gaps = 193/1340 (14%)

Query: 131  VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS 190
            VF+QTDK  YKP Q+    I   F D   + T  NI +KDP++N I QW +  S   +  
Sbjct: 110  VFVQTDKPTYKPGQKDVNGIAQFFLDTYTF-TYPNITLKDPQNNRIFQWQNVTSFRNITQ 168

Query: 191  KTFQLSSHPILGDWSIQVQVNDQ-TYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGT 249
             +FQL S P+ GD+ I V+ N + T    F V  YVLPKFEVT+  P   +++       
Sbjct: 169  LSFQLISEPMFGDYWIVVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVD 228

Query: 250  ITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEM--KNVMDSSN 307
            + AKYT+G+PV+G              K  I    +   S+N   ND E+  + +    N
Sbjct: 229  VCAKYTFGQPVQG--------------KTQIRVCREYFSSSNCEKNDNEICEQFIAQLEN 274

Query: 308  GL------SEYLDLSSPG---PVEILTTVTESVTG---ISRNVSTNVFFKQHDYIIEFFD 355
            G       ++   L   G      +   VTE  TG   +  +  T+VF  Q    + F +
Sbjct: 275  GCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLLGTVNFEN 334

Query: 356  YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
              T  +  +++  T+K +  D N + +  +       + Q    + + G+ + ++  EA 
Sbjct: 335  MDTFYRRGISYFGTLKFS--DPNNVPMVNK-------LLQLELNDEFIGNYTTDENGEA- 384

Query: 416  QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGS---KSSMAVHSLF-KSPSKTYIQLK 471
                +++  S  F  EF +   ++ ++ K+ +L S      +  H L  +  S+T   LK
Sbjct: 385  ---QFSIDTSDIFDPEFNL--KATYVRPKSCYLPSWLTPQYLDAHFLVSRFYSRTNSFLK 439

Query: 472  TRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQ---LVAVGKQNSTM------------ 516
               E  ++    + VV+ +  L   +Y   S  +   LV++   +               
Sbjct: 440  IVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRISSSPIYTA 499

Query: 517  ------FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEP 570
                  F L+      P A + VY +   GEI++D ++  V   FK+K+ + +S  +  P
Sbjct: 500  WNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLP 559

Query: 571  SEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITME---NVVHELELYNTGYY----- 622
                SL +    P     + AVD +V L+ +   ++ E   N+V  +E Y   Y+     
Sbjct: 560  GSNASLYLQAA-PVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLD 618

Query: 623  ----------LGMFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNA 658
                        MF N               + + +  GL V T+ +  K  +  +    
Sbjct: 619  DGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRL 678

Query: 659  EYAERFMEENEG----HIVDIHDFSLGSSPH---------VRKHFPETWIWLDTNMGYRI 705
               +    E E     H V       G +           VR +FPETW+W   ++    
Sbjct: 679  PLPKPLYLETENYGPMHSVPSRIACRGENADYVEQAIIQTVRTNFPETWMWDLVSVDSSG 738

Query: 706  YQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFA 765
                   +PD+IT W A+GF ++ D+G G+++T   L+  QPFFI +  P+SV++ E+F 
Sbjct: 739  SANLSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVSQPFFIEIASPFSVVQNEQFD 797

Query: 766  LEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPT 825
            L +  F+YL    E+ V +E+S  ++  + + +IN +      ++ +    T ++ I P 
Sbjct: 798  LIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGSE-----VIQAGGRKTNIWTIIPK 852

Query: 826  HLGEIPITVTALSPTAS---------------DAVTQMILVKAEGIEKSYSQSILLDLTD 870
             LG++ ITV A S  +S               D V +  LV+ EGIEK  +QS L+  T+
Sbjct: 853  KLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEKERTQSFLI-CTE 911

Query: 871  NRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFA 930
                S    L    P + V GS R   T +GD+LG ++  L  +++MPYG GEQN    A
Sbjct: 912  GAKASKQGVLDL--PNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGGGEQNAALLA 968

Query: 931  PNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSA 990
             + Y+LDYL   +QLT+ ++ KA   +  GYQR+L ++  DGS+S F   +  GS WLSA
Sbjct: 969  SDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSA 1028

Query: 991  FVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTA 1050
               +       ++ ID+NV  +T  WL   QK++G F + G++ +   +GG++  ++LTA
Sbjct: 1029 LTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTA 1088

Query: 1051 YIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEA-LN 1109
            Y+V              ++ ++  LE+    G+++ Y  A++ YA +  G  K  E+ L 
Sbjct: 1089 YVVGMFFEAGLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQ 1148

Query: 1110 MLTWRAEQEGGMQFWVSSESKLSDS------WQPRSLDIEVAAYALLSHFLQFQTSEGIP 1163
             L   A +   + +W       ++       W P S   E + Y LL+       S  IP
Sbjct: 1149 TLDQSATKLNNVIYWERERKPKTEEFPSFIPWAP-SAQTEKSCYVLLA-----VISRKIP 1202

Query: 1164 -------IMRWLSRQRNSLGGFASTQDTTVA--LKALSEFAALMNTERTNIQVTVTGPS- 1213
                   I++WL++Q NS GGF+S Q   V   L A+     L +  +  +  +  G S 
Sbjct: 1203 DLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSKNQNTVTFSSEGSSE 1262

Query: 1214 ---SPSPLAVVQ-------PTAVNISANGFGFAICQLNVVYNV----KASGSSRRRRSIQ 1259
               +     +VQ       P    +   G G    Q  + YNV    KASG         
Sbjct: 1263 IQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASG--------- 1313

Query: 1260 NQEAFDLDVAVKENKDDLNHVDLNVCTSFSG-PGRSGMALMEVNLLSGFMVPSEAISLSE 1318
                F L + + +N   L   DL V   ++G   +S M +++V +LSGF     +I    
Sbjct: 1314 ----FSLSLEIVKNY-SLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVN 1368

Query: 1319 TVKKVEYDHGKLNLYLDSVN 1338
                + +       Y D +N
Sbjct: 1369 NRSLIFHHKDSYIEYKDKIN 1388


>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
          Length = 1353

 Score =  360 bits (924), Expect = 5e-99
 Identities = 343/1310 (26%), Positives = 570/1310 (43%), Gaps = 204/1310 (15%)

Query: 131  VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS 190
            VF+QTDK  YKP Q+    I   F D   + T  NI +KDP++N I Q  +  S   +  
Sbjct: 61   VFVQTDKPTYKPGQKDVNGIAQFFLDTYTF-TYPNITLKDPQNNRIFQRQNVTSFRNITQ 119

Query: 191  KTFQLSSHPILGDWSIQVQVND-QTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGT 249
             +FQL S P+ GD+ I V+ N  +T    F V  YVLPKFEVT+  P   +++       
Sbjct: 120  LSFQLISEPMFGDYWIVVKRNSRETVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVD 179

Query: 250  ITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEM--KNVMDSSN 307
            + AKY +G+PV+G+  +      F               S+N   N+ E+  + +    N
Sbjct: 180  VCAKYNFGQPVQGETQIRVCREYF--------------SSSNCEKNENEICEQFIAQLEN 225

Query: 308  GL------SEYLDLSSPG---PVEILTTVTESVTG---ISRNVSTNVFFKQHDYIIEFFD 355
            G       ++   L   G      +   VTES TG   +  +  T+VF  Q    + F +
Sbjct: 226  GCVSQIVNTKVFQLYRSGLFMTFHVAVIVTESGTGNYFMQISEKTSVFITQLLGTVNFEN 285

Query: 356  YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
              T  +  +++  T+K +  D N + +  +       + Q    + + G+ + ++  EA 
Sbjct: 286  MDTFYRRGISYFGTLKFS--DPNNVPMVNK-------LLQLELNDEFIGNYTTDENGEA- 335

Query: 416  QKINYTVPQSGTFKIEFP-----ILEDSSELQ-------LKAYFLGSKSSMAVHSLFKS- 462
                +++  S  F  EF      +  +S  L        L A+FL S+     +S  K  
Sbjct: 336  ---QFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIV 392

Query: 463  PSKTYIQLKTR----------------DENIKVGSPFELVVSGNKRLKELSYMVVSRGQL 506
            P    ++   +                D N+K    F  +VS +       + + S    
Sbjct: 393  PEPKQLECNQQKVVTVHYSLNSEAYEDDSNVK----FFYLVSLSHDSGNFQHRISSSPIY 448

Query: 507  VAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKV 566
             A     S   S++ + +  P A + VY +   GEI++D ++  V   FK+K+ + +S  
Sbjct: 449  TAWNGNFSFPISISADLA--PAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNE 506

Query: 567  KAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITME---NVVHELELYNTGYY- 622
            +  P    SL +    P     + AVD++V L+ +   ++ E   N+V  +E Y   Y+ 
Sbjct: 507  QGLPGSNASLCLQAA-PVLFCALRAVDRNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHG 565

Query: 623  --------------LGMFMNS--------------FAVFQECGLWVLTDANLTKDYIDGV 654
                            MF N               + + +  GL V T+ +  K  +  +
Sbjct: 566  LNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVM 625

Query: 655  YDNAEYAERFMEENE---------------GHIVDIHDFSLGSSPHVRKHFPETWIWLDT 699
                   +    E E               G   D  + ++  +  VR +FPETW+W   
Sbjct: 626  ERRLPLPKPLYLETENYGPMRSVPSRIACRGENADYVEQAIIQT--VRTNFPETWMWDLV 683

Query: 700  NMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVI 759
            ++           +PD+IT W A+GF ++ D+G G+++T   L+  QPFFI +  P+SV+
Sbjct: 684  SVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVSQPFFIEIASPFSVV 742

Query: 760  RGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVL 819
            + E+F L + +F+Y     E+ V +E+S  ++  + + +IN +      ++ +    T +
Sbjct: 743  QNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANIHTLKINGSE-----VIQAGGRKTNV 797

Query: 820  FPIRPTHLGEIPITVTALSPTAS---------------DAVTQMILVKAEGIEKSYSQSI 864
            + I P  LG++ ITV A S  +S               D V Q  LV+ EGIEK  +QS 
Sbjct: 798  WTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVQSFLVEPEGIEKERTQSF 857

Query: 865  LLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQ 924
            L+  T+    S    L    P + V GS R   T +GD+LG ++  L  +++MPYG GEQ
Sbjct: 858  LI-CTEGAKASKQGVLDL--PNDVVEGSARGFFTVVGDILGLALQNLV-VLQMPYGSGEQ 913

Query: 925  NMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSG 984
            N    A + Y+LDYL   +QLT+ ++ KA   +  GYQR+L ++  DGS+S F      G
Sbjct: 914  NAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQSQKG 973

Query: 985  STWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKS 1044
            S  LSA   +       Y+ ID+NV  +T  WL   QK++G F + G++ +   +GG++ 
Sbjct: 974  SIXLSALTFKTLERMKKYVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWEGGDEE 1033

Query: 1045 PVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKA 1104
             ++LTAY+V              ++ ++  LE+    G+++ Y  A++ YA +  G  K 
Sbjct: 1034 DISLTAYVVGMFFEAGLNFTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQ 1093

Query: 1105 KEA-LNMLTWRAEQEGGMQFWVSSESKLSDS------WQPRSLDIEVAAYALLSHFLQFQ 1157
             E+ L  L   A +   + +W       ++       W P S   E + Y LL+      
Sbjct: 1094 VESLLQTLDQSAPKLNNVIYWERERKPKTEEFPSFIPWAP-SAQTEKSCYVLLA-----V 1147

Query: 1158 TSEGIP-------IMRWLSRQRNSLGGFASTQDTTVAL---------KALSEFAALMNTE 1201
             S  IP       I++WL+++ NS GGF+S Q   V L         K       L + +
Sbjct: 1148 ISRKIPDLTYASKIVQWLAQRMNSHGGFSSNQVINVGLILIAICLMQKLARGEEGLFSKD 1207

Query: 1202 RTNIQVTVTGPSSPSPL-----AVVQ-------PTAVNISANGFGFAICQLNVVYNV--- 1246
            +  +  +  G S    +      +VQ       P    +   G G    Q  + YNV   
Sbjct: 1208 QNTVTFSSEGSSEIFQVNGHNRLLVQRSEVTQAPGEYTVDVEGHGCTFIQATLKYNVLLP 1267

Query: 1247 -KASGSSRRRRSIQN--QEAFDLDVAVK----ENKDDLNHVDLNVCTSFS 1289
             KASG S     ++N    AFDL V +K     NK  +  +D+ + + F+
Sbjct: 1268 KKASGFSLSLEIVKNYSSTAFDLTVTLKYTGIRNKSSMVVIDVKMLSGFT 1317


>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
            8 [Homo sapiens]
          Length = 1932

 Score =  315 bits (808), Expect = 2e-85
 Identities = 206/566 (36%), Positives = 303/566 (53%), Gaps = 62/566 (10%)

Query: 874  QSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNI 933
            +S  +  +   P   + GSER   + IGDV+GP++N L +L+R+P+GCGEQNMI+FAPN+
Sbjct: 1144 ESYSEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGEQNMIHFAPNV 1203

Query: 934  YILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVL 993
            ++L YL K +QL+  ++ +   ++ QGYQR+L Y+R+DGS+SAFG  D SGS WL+AFVL
Sbjct: 1204 FVLKYLQKTQQLSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDASGSMWLTAFVL 1263

Query: 994  RCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIV 1053
            + F +A  +I +D   L    +W+   Q+++G F   GRV++ ++QGG    V LTAY+V
Sbjct: 1264 KSFAQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHGTVPLTAYVV 1323

Query: 1054 TSLL--GYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNML 1111
             +LL  G    +      ++ HFLES     + D Y+ AL TYAL+ + SP A EAL  L
Sbjct: 1324 VALLETGTASEEERGSTDKARHFLESAAPLAM-DPYSCALTTYALTLLRSPAAPEALRKL 1382

Query: 1112 TWRAEQEGGMQFWVSSES---------KLSD--SWQPRSLDIEVAAYALLSHFLQFQTSE 1160
               A    G+  W  S S           SD  S    S ++E+ AYALL++ L    + 
Sbjct: 1383 RSLAIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVEMTAYALLTYTLLGDVAA 1442

Query: 1161 GIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAAL---------MNTERTNIQVTVTG 1211
             +P+++WLS+QRN+LGGF+STQDT VAL+AL+E+A L         ++   TN+    T 
Sbjct: 1443 ALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYAGGINLTVSLASTNLDYQETF 1502

Query: 1212 PSSPSPLAVVQ-------PTAVNISANGFGFAICQLNVVYNVK---ASGSSRRRRSIQNQ 1261
                +   V+Q       PT + +SA G G  + Q++V YNV    A  + +   S+Q  
Sbjct: 1503 ELHRTNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQIDVTYNVPDPVAKPAFQLLVSLQEP 1562

Query: 1262 E----------------------AFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALM 1299
            E                      A D D A  ++  +   V L VCT +   G S MA++
Sbjct: 1563 EAQGRPPPMPASAAEGSRGDWPPADDDDPAADQHHQEYK-VMLEVCTRWLHAGSSNMAVL 1621

Query: 1300 EVNLLSGFMVPSEA-----ISLSETVKKVEYDHGKLNLYLDSV-NETQFCVNIPAVRNFK 1353
            EV LLSGF    E+     +     +K+ E    ++  Y D + +    CV   A+R   
Sbjct: 1622 EVPLLSGFRADIESLEQLLLDKHMGMKRYEVAGRRVLFYFDEIPSRCLTCVRFRALRECV 1681

Query: 1354 VSNTQDASVSIVDYYEPRRQAVRSYN 1379
            V  T    VS+ DYYEP  +A R YN
Sbjct: 1682 VGRTSALPVSVYDYYEPAFEATRFYN 1707



 Score =  244 bits (624), Expect = 3e-64
 Identities = 253/967 (26%), Positives = 412/967 (42%), Gaps = 170/967 (17%)

Query: 18  AALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAE 77
           AA   APG  +L+ AP + R G    I V +  + P +VTV+A+L+         V++++
Sbjct: 72  AAQPQAPG--YLIAAPSVFRAGVEEVISVTIF-NSPREVTVQAQLVAQGE----PVVQSQ 124

Query: 78  G-VFEKGSFKTLTLPSLPLNSADEIYELRVTGR---TQDEILFSNSTRLSFETKRISVFI 133
           G + +KG+ K L +P+     A     L+V GR    ++  LF N T ++ + +  SVFI
Sbjct: 125 GAILDKGTIK-LKVPTGLRGQA----LLKVWGRGWQAEEGPLFHNQTSVTVDGRGASVFI 179

Query: 134 QTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDL-GVISKT 192
           QTDK +Y+P+  V   I T+  + +P    L   I DP+ + + +W   +    G+ + +
Sbjct: 180 QTDKPVYRPQHRVLISIFTVSPNLRPVNEKLEAYILDPRGSRMIEWRHLKPFCCGITNMS 239

Query: 193 FQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITA 252
           F LS  P+LG+W I V++    Y +SF+V +YVLPKFE+ +  P Y         GT+ A
Sbjct: 240 FPLSDQPVLGEWFIFVEMQGHAYNKSFEVQKYVLPKFELLIDPPRYIQDLDACETGTVRA 299

Query: 253 KYTYGKPVKGD--VTLTFLPLSFWGKK--KNITKTFKINGSANFSFNDEEMKNVMDSSNG 308
           +YT+GKPV G   + +T   + ++  +  + + +T KI GS +F     +M         
Sbjct: 300 RYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLRTTKILGSRDFDICVRDM--------- 350

Query: 309 LSEYLDLSSPGPVEILTTVTESVTG---ISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLN 365
           +   +     G V I   VT SV G   ++ + ST V  +  D I    D     KP L 
Sbjct: 351 IPADVPEHFRGRVSIWAMVT-SVDGSQQVAFDDSTPVQRQLVD-IRYSKDTRKQFKPGLA 408

Query: 366 FTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQS 425
           +   V+++  DG+       +    +T     YT                   +  V Q 
Sbjct: 409 YVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYT-------------------SEVVSQR 449

Query: 426 GTFKIEFPILEDSSE---LQLKAYFLGSK--------SSMAVHSLFKSPSKTYIQLKTRD 474
           G    E P +  S++   L+ K   L  K        S +++ S + SPS+ Y+QL+   
Sbjct: 450 GLVGFEIPSIPTSAQHVWLETKVMALNGKPVGAQYLPSYLSLGSWY-SPSQCYLQLQPPS 508

Query: 475 ENIKVGSPFELVVSGNKRLK-ELSYMVVSRGQLVAVGKQNS------------------- 514
             ++VG      V         L Y V +RG +V  G+Q +                   
Sbjct: 509 HPLQVGEEAYFSVKSTCPCNFTLYYEVAARGNIVLSGQQPAHTTQQRSKRAAPALEKPIR 568

Query: 515 ---------------------TMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQL 553
                                T   L    S  P   ++V+Y+ ++GE ++D L+  V+ 
Sbjct: 569 LTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEGVADSLQFAVET 628

Query: 554 VFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHE 613
            F+N++ + +S  + +P E V LRI   +  S V + AVDKSV L+ +   +T   V  E
Sbjct: 629 FFENQVSVTYSANETQPGEVVDLRIRAAR-GSCVCVAAVDKSVYLLRSGFRLTPAQVFQE 687

Query: 614 LELYNTG-----------------------------YYLGMFMNSFAVFQECGLWVLTDA 644
           LE Y+                               +  G+  +S   F E GL V+TD 
Sbjct: 688 LEDYDVSDSFGVSREDGPFWWAGLTAQRRRRSSVFPWPWGITKDSGFAFTETGLVVMTDR 747

Query: 645 NLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKH--FPETWIWLDTNMG 702
                  DG     E    F + + G +V +           RK   FPETWIW   N+ 
Sbjct: 748 VSLNHRQDGGLYTDEAVPAF-QPHTGSLVAVAPSRHPPRTEKRKRTFFPETWIWHCLNIS 806

Query: 703 YRIYQ-EFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRG 761
               +    V VPDSITSWV     +S   GLG+   P  L+ F+PFF+   LP  +IRG
Sbjct: 807 DPSGEGTLSVKVPDSITSWVGEAVALSTSQGLGI-AEPSLLKTFKPFFVDFMLPALIIRG 865

Query: 762 EEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFP 821
           E+  + ++++NY+    EV + +        +    + + T   + + V   +   +   
Sbjct: 866 EQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFVGHPGKRHVT---KKMCVAPGEAEPIWVV 922

Query: 822 IRPTHLGEIPITVTALS-------------------------PTASDAVTQMILVKAEGI 856
           +  + LG   IT  AL+                         P   D V + ++V+AEG+
Sbjct: 923 LSFSDLGLNNITAKALAYGDTNCCRDGRSSKHPEENHADRRVPIGVDHVRRSVMVEAEGV 982

Query: 857 EKSYSQS 863
            ++Y+ S
Sbjct: 983 PRAYTYS 989


>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
            sapiens]
          Length = 1698

 Score =  229 bits (584), Expect = 1e-59
 Identities = 225/808 (27%), Positives = 344/808 (42%), Gaps = 126/808 (15%)

Query: 686  VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
            VR  FPE W+W    +    +Q   + +PDS+T+W   G  +S+  GL    TPV+L+ F
Sbjct: 774  VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830

Query: 746  QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805
            + F + L LP SV R E+  L   ++NYL     V V +   +   +          G  
Sbjct: 831  REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884

Query: 806  QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862
            Q +LVP+     V F + PT    + + V A         DAV++++ ++ EG    + +
Sbjct: 885  QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942

Query: 863  SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911
             ++ +L  N L    +TL    +  PN +   +    V++TA    D LG     S  G+
Sbjct: 943  ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000

Query: 912  ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968
            ASL+R+P GCGEQ MI  AP +    YL K +Q   L    K+ A+  +++GY R   ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060

Query: 969  REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028
            + DGS++A+ + D   STWL+AFVL+    A   +      L  T  WL   Q+++G F 
Sbjct: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118

Query: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074
            DP  V+   +QG   GN   V LTA++  +L               K +    + ++  F
Sbjct: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178

Query: 1075 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1132
            L  + S G+   +  A+  YAL+   +P      A N L   A++ G   +W S     S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238

Query: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177
            ++  P               +L IE  AYALL   L    +E       WL+RQ +  GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298

Query: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVTGPSSPSPLAVVQPTAVNISANGFGFA 1236
            F STQDT +AL ALS +  A   TE   + VT++                +   NGF   
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLS----------------STGRNGFKSH 1342

Query: 1237 ICQLN----------------VVYNVKASGSSRRRRSI---------QNQEAFDLDVAV- 1270
              QLN                   NVK  G+S+    +         +N    DL + V 
Sbjct: 1343 ALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVT 1402

Query: 1271 --------KENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSG-----FMVPSEAISLS 1317
                     E  +D    + +   +   P      +  + L  G          +  SLS
Sbjct: 1403 VKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKLTSLS 1462

Query: 1318 ET-VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVR 1376
            +  V   E +   + LY DSV  ++ CV   AV+   V   Q AS ++ DYY P R+   
Sbjct: 1463 DRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSV 1522

Query: 1377 SYNSEVK------LSSCDLCSDVQGCRP 1398
             Y +  K      L S ++C   +G  P
Sbjct: 1523 FYGAPSKSRLLATLCSAEVCQCAEGKCP 1550



 Score =  100 bits (250), Expect = 8e-21
 Identities = 146/656 (22%), Positives = 270/656 (41%), Gaps = 67/656 (10%)

Query: 26  PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83
           PR L+ +P ++  G  +++GV+L +    QV   +  L+  S  N+  S      +  + 
Sbjct: 21  PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80

Query: 84  SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129
            F  L+L  +PL  A            E+  +  +   +D +  + + +   L F ++R 
Sbjct: 81  DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139

Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189
            +F+QTD+ +Y P Q V++R+  L    +P   ++ +++++     +++         + 
Sbjct: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198

Query: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244
              F +      G W I  + +D     S   F+V +YVLP FEV + TP   Y      
Sbjct: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257

Query: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297
           HL+     I A+Y YGKPV+G   + F  L   GKK       ++T  +NG ++ S +  
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317

Query: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355
           E ++ ++  N G+++   L     + +   + E   G       T+ +F    + ++   
Sbjct: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSK 373

Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
               L P   F     V    G+        + + + V         S + S    +  V
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418

Query: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473
           Q I      SG   I   I +  SELQL         ++A  ++   PS    ++ ++  
Sbjct: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWP 478

Query: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526
           D    +VG    L    V          YM++SRGQ+V +    K+  T  S+  ++   
Sbjct: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538

Query: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584
           P    + +Y   D   +++ L++ VQ    + K++L     K     E V L +  T   
Sbjct: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596

Query: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
           ++V + A+D ++    + +   + M  V   +  Y+ G   G   ++  VFQ  GL
Sbjct: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652


>gi|115298678 complement component 3 precursor [Homo sapiens]
          Length = 1663

 Score =  216 bits (549), Expect = 2e-55
 Identities = 208/783 (26%), Positives = 353/783 (45%), Gaps = 98/783 (12%)

Query: 687  RKHFPETWIWLDTNMGYR-----IYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741
            R  FPE+W+W   ++          +   + + DSIT+W      +S+  G+     P E
Sbjct: 764  RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGI-CVADPFE 822

Query: 742  LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIE--KSDKFDILMTSNEI 799
            +   Q FFI L LPYSV+R E+  +   ++NY +   E+KV +E   +  F  L T+   
Sbjct: 823  VTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNY-RQNQELKVRVELLHNPAFCSLATTKR- 880

Query: 800  NATGHQQTLLVPSEDGATVLFPIRP--THLGEIPITVTALSPTASDAVTQMILVKAEGIE 857
                HQQT+ +P +   +V + I P  T L E+ +         SD V + + V  EGI 
Sbjct: 881  ---RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIR 937

Query: 858  KSYSQSI-LLDLTDNRLQSTLK------TLSFSFPPNTVTGSERVQITAIGDVLGPSING 910
             + + ++  LD      +   K       LS   P         +Q T +  +   +++ 
Sbjct: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997

Query: 911  --LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEK---ALSFMRQGYQREL 965
              L  LI  P GCGEQNMI   P +  + YL + +Q      EK   AL  +++GY ++L
Sbjct: 998  ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057

Query: 966  LYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWL-KGHQKSN 1024
             +++   +F+AF    P  STWL+A+V++ F  A   I ID  VL     WL    QK +
Sbjct: 1058 AFRQPSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115

Query: 1025 GEFWDPGRVIHSELQGG----NKSPVTLTAYIVTSLLGYR---KYQPNI---DVQESIHF 1074
            G F +   VIH E+ GG    N+  + LTA+++ SL   +   + Q N     + ++  F
Sbjct: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF 1175

Query: 1075 LESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDS 1134
            LE+ +   +  +YT+A+  YAL+ +G  K       LT   ++      W     +L   
Sbjct: 1176 LEANY-MNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR----WEDPGKQL--- 1227

Query: 1135 WQPRSLDIEVAAYALLSHFLQFQTSEGI-PIMRWLSRQRNSLGGFASTQDTTVALKALSE 1193
                  ++E  +YALL+  LQ +  + + P++RWL+ QR   GG+ STQ T +  +AL++
Sbjct: 1228 -----YNVEATSYALLA-LLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQ 1281

Query: 1194 FAA-LMNTERTNIQVTVTGPSSPSPLA---------------VVQPTAVNISANGFGFAI 1237
            +     + +  N+ V++  PS  S +                  +     ++A G G   
Sbjct: 1282 YQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGT 1341

Query: 1238 CQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV-------KENKDDLNHVDLNVCTSFSG 1290
              +  +Y+ KA       +       FDL V +       K  +D  N + L +CT + G
Sbjct: 1342 LSVVTMYHAKAKDQLTCNK-------FDLKVTIKPAPETEKRPQDAKNTMILEICTRYRG 1394

Query: 1291 PGRSGMALMEVNLLSGFMVPSE-----AISLSETVKKVEY-----DHGKLNLYLDSVNET 1340
               + M+++++++++GF   ++     A  +   + K E      D   L +YLD V+ +
Sbjct: 1395 DQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHS 1454

Query: 1341 Q-FCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCD-LCSDVQGCRP 1398
            +  C+     + F V   Q  +V +  YY       R Y+ E +    + LC D + CR 
Sbjct: 1455 EDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRD-ELCRC 1513

Query: 1399 CED 1401
             E+
Sbjct: 1514 AEE 1516



 Score =  104 bits (260), Expect = 5e-22
 Identities = 127/536 (23%), Positives = 240/536 (44%), Gaps = 49/536 (9%)

Query: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQ-WLSQQSDLGVI 189
           +FIQTDK +Y P   V +RI T+     P   ++ + I++P+   ++Q  LS Q+ LGV+
Sbjct: 130 LFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVL 189

Query: 190 SKTFQLSSHPILGDWSIQVQVND---QTYYQSFQVSEYVLPKFEVTLQ--TPLYCSMNSK 244
             ++ +     +G W I+    +   Q +   F+V EYVLP FEV ++     Y   N K
Sbjct: 190 PLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEK 249

Query: 245 HLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFK----INGSANFSFNDEEMK 300
            L  TITA++ YGK V+G   + F  +    ++ ++ ++ K     +GS     +    K
Sbjct: 250 GLEVTITARFLYGKKVEGTAFVIF-GIQDGEQRISLPESLKRIPIEDGSGEVVLS---RK 305

Query: 301 NVMDS-SNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTV 359
            ++D   N  +E  DL         T +  S + + +   + +      Y I F      
Sbjct: 306 VLLDGVQNPRAE--DLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKY 363

Query: 360 LKPSLNFTATVKVTRADGN---QLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQ 416
            KP + F   V VT  DG+   ++ +  +  + V ++TQ +     S +   +QK     
Sbjct: 364 FKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQK----- 418

Query: 417 KINYTVPQSGTFKIEFPILEDSSE-LQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDE 475
            ++ TV    T K E    E ++  +Q   Y     S+  +H    S  +T ++     E
Sbjct: 419 PLSITV---RTKKQELSEAEQATRTMQALPYSTVGNSNNYLH---LSVLRTELR---PGE 469

Query: 476 NIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGK------QNSTMFSLTPENSWTPKA 529
            + V     +  +   +++  +Y+++++G+L+  G+      Q+  +  L+    + P  
Sbjct: 470 TLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSF 529

Query: 530 CVIVYY----IEDDGEIISDVLKIPVQ--LVFKNKIKLYWSKVKAE-PSEKVSLRISVTQ 582
            ++ YY         E+++D + + V+   V    +K   S+ +   P ++++L+I    
Sbjct: 530 RLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDH 589

Query: 583 PDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
              +V +VAVDK V ++N  N +T   +   +E  + G   G   +   VF + GL
Sbjct: 590 GARVV-LVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGL 644


>gi|178557739 complement component 4B preproprotein [Homo sapiens]
          Length = 1744

 Score =  208 bits (530), Expect = 3e-53
 Identities = 175/574 (30%), Positives = 266/574 (46%), Gaps = 64/574 (11%)

Query: 686  VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
            VR  FPE W+W    +    +Q   + +PDS+T+W   G  +S+  GL    TPV+L+ F
Sbjct: 774  VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830

Query: 746  QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805
            + F + L LP SV R E+  L   ++NYL     V V +   +   +          G  
Sbjct: 831  REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884

Query: 806  QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862
            Q +LVP+     V F + PT    + + V A         DAV++++ ++ EG    + +
Sbjct: 885  QQVLVPAGSARPVAFSVVPTAATAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942

Query: 863  SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911
             ++ +L  N L    +TL    +  PN +   +    V++TA    D LG     S  G+
Sbjct: 943  ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000

Query: 912  ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968
            ASL+R+P GCGEQ MI  AP +    YL K +Q   L    K+ A+  +++GY R   ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060

Query: 969  REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028
            + DGS++A+       STWL+AFVL+    A   +      L  T  WL   Q+++G F 
Sbjct: 1061 KADGSYAAW--LSRGSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118

Query: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074
            D   VIH  +QG   GN   V LTA++  +L               K +    + ++  F
Sbjct: 1119 DLSPVIHRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKASSF 1178

Query: 1075 LESEFSRGISDNYTLALITYALSSVGSPKAKE--ALNMLTWRAEQEGGMQFWVSSESKLS 1132
            L  + S G+   +  A+  YAL+   +P      A N L   A++ G   +W S     S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238

Query: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177
            ++  P               +L IE  AYALL   L    +E       WL+RQ +  GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298

Query: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVT 1210
            F STQDT +AL ALS +  A   TE   + VT++
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLS 1332



 Score =  103 bits (257), Expect = 1e-21
 Identities = 147/656 (22%), Positives = 271/656 (41%), Gaps = 67/656 (10%)

Query: 26  PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83
           PR L+ +P ++  G  +++GV+L +    QV   +  L+  S  N+  S      +  + 
Sbjct: 21  PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80

Query: 84  SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129
            F  L+L  +PL  A            E+  +  +   +D +  + + +   L F ++R 
Sbjct: 81  DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139

Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189
            +F+QTD+ +Y P Q V++R+  L    +P   ++ +++++     +++         + 
Sbjct: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198

Query: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244
              F +      G W I  + +D     S   F+V +YVLP FEV + TP   Y      
Sbjct: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257

Query: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297
           HL+     I A+Y YGKPV+G   + F  L   GKK       ++T  +NG ++ S +  
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317

Query: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355
           E ++ ++  N G+++   L     + +   + ES  G       T+ +F    + ++   
Sbjct: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSK 373

Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
               L P   F     V    G+        + + + V         S + S    +  V
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418

Query: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473
           Q I      SG   I   I +  SELQL         ++A  ++   PS    ++ ++  
Sbjct: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERP 478

Query: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526
           D    +VG    L    V          YM++SRGQ+V +    K+  T  S+  ++   
Sbjct: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538

Query: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584
           P    + +Y   D   +++ L++ VQ    + K++L     K     E V L +  T   
Sbjct: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596

Query: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
           ++V + A+D ++    + +   + M  V   +  Y+ G   G   ++  VFQ  GL
Sbjct: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 47/142 (33%), Positives = 67/142 (47%), Gaps = 12/142 (8%)

Query: 1269 AVKENKDDLNHVDLNVCTSFSGP-GRSGMALMEVNLLSGFMVP----SEAISLSET-VKK 1322
            A K  ++  + V   VC   +G  G SGMA+ +V LLSGF        +  SLS+  V  
Sbjct: 1455 APKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSH 1514

Query: 1323 VEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEV 1382
             E +   + LY DSV  ++ CV   AV+   V   Q AS ++ DYY P R+    Y +  
Sbjct: 1515 FETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPS 1574

Query: 1383 K------LSSCDLCSDVQGCRP 1398
            K      L S ++C   +G  P
Sbjct: 1575 KSRLLATLCSAEVCQCAEGKCP 1596


>gi|67190748 complement component 4A preproprotein [Homo sapiens]
          Length = 1744

 Score =  208 bits (529), Expect = 3e-53
 Identities = 175/574 (30%), Positives = 268/574 (46%), Gaps = 64/574 (11%)

Query: 686  VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
            VR  FPE W+W    +    +Q   + +PDS+T+W   G  +S+  GL    TPV+L+ F
Sbjct: 774  VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830

Query: 746  QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805
            + F + L LP SV R E+  L   ++NYL     V V +   +   +          G  
Sbjct: 831  REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884

Query: 806  QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862
            Q +LVP+     V F + PT    + + V A         DAV++++ ++ EG    + +
Sbjct: 885  QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942

Query: 863  SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911
             ++ +L  N L    +TL    +  PN +   +    V++TA    D LG     S  G+
Sbjct: 943  ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000

Query: 912  ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968
            ASL+R+P GCGEQ MI  AP +    YL K +Q   L    K+ A+  +++GY R   ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060

Query: 969  REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028
            + DGS++A+ + D   STWL+AFVL+    A   +      L  T  WL   Q+++G F 
Sbjct: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118

Query: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074
            DP  V+   +QG   GN   V LTA++  +L               K +    + ++  F
Sbjct: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178

Query: 1075 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1132
            L  + S G+   +  A+  YAL+   +P      A N L   A++ G   +W S     S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238

Query: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177
            ++  P               +L IE  AYALL   L    +E       WL+RQ +  GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQASAWLTRQGSFQGG 1298

Query: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVT 1210
            F STQDT +AL ALS +  A   TE   + VT++
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLS 1332



 Score =  103 bits (257), Expect = 1e-21
 Identities = 147/656 (22%), Positives = 271/656 (41%), Gaps = 67/656 (10%)

Query: 26  PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83
           PR L+ +P ++  G  +++GV+L +    QV   +  L+  S  N+  S      +  + 
Sbjct: 21  PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80

Query: 84  SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129
            F  L+L  +PL  A            E+  +  +   +D +  + + +   L F ++R 
Sbjct: 81  DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139

Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189
            +F+QTD+ +Y P Q V++R+  L    +P   ++ +++++     +++         + 
Sbjct: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198

Query: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244
              F +      G W I  + +D     S   F+V +YVLP FEV + TP   Y      
Sbjct: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257

Query: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297
           HL+     I A+Y YGKPV+G   + F  L   GKK       ++T  +NG ++ S +  
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317

Query: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355
           E ++ ++  N G+++   L     + +   + ES  G       T+ +F    + ++   
Sbjct: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSK 373

Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
               L P   F     V    G+        + + + V         S + S    +  V
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418

Query: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473
           Q I      SG   I   I +  SELQL         ++A  ++   PS    ++ ++  
Sbjct: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERP 478

Query: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526
           D    +VG    L    V          YM++SRGQ+V +    K+  T  S+  ++   
Sbjct: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538

Query: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584
           P    + +Y   D   +++ L++ VQ    + K++L     K     E V L +  T   
Sbjct: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596

Query: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
           ++V + A+D ++    + +   + M  V   +  Y+ G   G   ++  VFQ  GL
Sbjct: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 47/142 (33%), Positives = 67/142 (47%), Gaps = 12/142 (8%)

Query: 1269 AVKENKDDLNHVDLNVCTSFSGP-GRSGMALMEVNLLSGFMVP----SEAISLSET-VKK 1322
            A K  ++  + V   VC   +G  G SGMA+ +V LLSGF        +  SLS+  V  
Sbjct: 1455 APKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSH 1514

Query: 1323 VEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEV 1382
             E +   + LY DSV  ++ CV   AV+   V   Q AS ++ DYY P R+    Y +  
Sbjct: 1515 FETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPS 1574

Query: 1383 K------LSSCDLCSDVQGCRP 1398
            K      L S ++C   +G  P
Sbjct: 1575 KSRLLATLCSAEVCQCAEGKCP 1596


>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
            sapiens]
          Length = 1744

 Score =  208 bits (529), Expect = 3e-53
 Identities = 175/574 (30%), Positives = 268/574 (46%), Gaps = 64/574 (11%)

Query: 686  VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
            VR  FPE W+W    +    +Q   + +PDS+T+W   G  +S+  GL    TPV+L+ F
Sbjct: 774  VRSFFPENWLWRVETVDR--FQILTLWLPDSLTTWEIHGLSLSKTKGL-CVATPVQLRVF 830

Query: 746  QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQ 805
            + F + L LP SV R E+  L   ++NYL     V V +   +   +          G  
Sbjct: 831  REFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLA------GGGGLA 884

Query: 806  QTLLVPSEDGATVLFPIRPTHLGEIPITVTALSP---TASDAVTQMILVKAEGIEKSYSQ 862
            Q +LVP+     V F + PT    + + V A         DAV++++ ++ EG    + +
Sbjct: 885  QQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA--IHRE 942

Query: 863  SILLDLTDNRLQSTLKTLSF--SFPPNTVTGSE---RVQITAIG--DVLGP----SINGL 911
             ++ +L  N L    +TL    +  PN +   +    V++TA    D LG     S  G+
Sbjct: 943  ELVYEL--NPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGV 1000

Query: 912  ASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQ---LTDNLKEKALSFMRQGYQRELLYQ 968
            ASL+R+P GCGEQ MI  AP +    YL K +Q   L    K+ A+  +++GY R   ++
Sbjct: 1001 ASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFR 1060

Query: 969  REDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFW 1028
            + DGS++A+ + D   STWL+AFVL+    A   +      L  T  WL   Q+++G F 
Sbjct: 1061 KADGSYAAWLSRD--SSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQADGSFQ 1118

Query: 1029 DPGRVIHSELQG---GNKSPVTLTAYIVTSL-----------LGYRKYQPNIDVQESIHF 1074
            DP  V+   +QG   GN   V LTA++  +L               K +    + ++  F
Sbjct: 1119 DPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSF 1178

Query: 1075 LESEFSRGISDNYTLALITYALSSVGSP--KAKEALNMLTWRAEQEGGMQFWVSSESKLS 1132
            L  + S G+   +  A+  YAL+   +P      A N L   A++ G   +W S     S
Sbjct: 1179 LGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQS 1238

Query: 1133 DSWQPR--------------SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGG 1177
            ++  P               +L IE  AYALL   L    +E       WL+RQ +  GG
Sbjct: 1239 NAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGG 1298

Query: 1178 FASTQDTTVALKALSEF-AALMNTERTNIQVTVT 1210
            F STQDT +AL ALS +  A   TE   + VT++
Sbjct: 1299 FRSTQDTVIALDALSAYWIASHTTEERGLNVTLS 1332



 Score =  100 bits (250), Expect = 8e-21
 Identities = 146/656 (22%), Positives = 270/656 (41%), Gaps = 67/656 (10%)

Query: 26  PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTAS--NLTVSVLEAEGVFEKG 83
           PR L+ +P ++  G  +++GV+L +    QV   +  L+  S  N+  S      +  + 
Sbjct: 21  PRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSER 80

Query: 84  SFKTLTLPSLPLNSAD-----------EIYELRVTGRTQDEILFSNSTR---LSFETKRI 129
            F  L+L  +PL  A            E+  +  +   +D +  + + +   L F ++R 
Sbjct: 81  DFALLSL-QVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRG 139

Query: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVI 189
            +F+QTD+ +Y P Q V++R+  L    +P   ++ +++++     +++         + 
Sbjct: 140 HLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KEVYMPSSIF 198

Query: 190 SKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP--LYCSMNSK 244
              F +      G W I  + +D     S   F+V +YVLP FEV + TP   Y      
Sbjct: 199 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGKPYILTVPG 257

Query: 245 HLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGSANFSFNDE 297
           HL+     I A+Y YGKPV+G   + F  L   GKK       ++T  +NG ++ S +  
Sbjct: 258 HLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKA 317

Query: 298 EMKNVMDSSN-GLSEYLDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFD 355
           E ++ ++  N G+++   L     + +   + E   G       T+ +F    + ++   
Sbjct: 318 EFQDALEKLNMGITDLQGLR----LYVAAAIIEYPGGEMEEAELTSWYFVSSPFSLDLSK 373

Query: 356 YTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAV 415
               L P   F     V    G+        + + + V         S + S    +  V
Sbjct: 374 TKRHLVPGAPFLLQALVREMSGSP------ASGIPVKV---------SATVSSPGSVPEV 418

Query: 416 QKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPS--KTYIQLKTR 473
           Q I      SG   I   I +  SELQL         ++A  ++   PS    ++ ++  
Sbjct: 419 QDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWP 478

Query: 474 DEN-IKVGSPFEL---VVSGNKRLKELSYMVVSRGQLVAVG---KQNSTMFSLTPENSWT 526
           D    +VG    L    V          YM++SRGQ+V +    K+  T  S+  ++   
Sbjct: 479 DSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLA 538

Query: 527 PKACVIVYYIEDDGEIISDVLKIPVQL-VFKNKIKLYWSKVKA-EPSEKVSLRISVTQPD 584
           P    + +Y   D   +++ L++ VQ    + K++L     K     E V L +  T   
Sbjct: 539 PSFYFVAFYYHGD-HPVANSLRVDVQAGACEGKLELSVDGAKQYRNGESVKLHLE-TDSL 596

Query: 585 SIVGIVAVDKSVNLMNASN--DITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
           ++V + A+D ++    + +   + M  V   +  Y+ G   G   ++  VFQ  GL
Sbjct: 597 ALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGL 652



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 47/142 (33%), Positives = 67/142 (47%), Gaps = 12/142 (8%)

Query: 1269 AVKENKDDLNHVDLNVCTSFSGP-GRSGMALMEVNLLSGFMVP----SEAISLSET-VKK 1322
            A K  ++  + V   VC   +G  G SGMA+ +V LLSGF        +  SLS+  V  
Sbjct: 1455 APKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSH 1514

Query: 1323 VEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEV 1382
             E +   + LY DSV  ++ CV   AV+   V   Q AS ++ DYY P R+    Y +  
Sbjct: 1515 FETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPS 1574

Query: 1383 K------LSSCDLCSDVQGCRP 1398
            K      L S ++C   +G  P
Sbjct: 1575 KSRLLATLCSAEVCQCAEGKCP 1596


>gi|38016947 complement component 5 preproprotein [Homo sapiens]
          Length = 1676

 Score =  181 bits (459), Expect = 4e-45
 Identities = 189/780 (24%), Positives = 353/780 (45%), Gaps = 101/780 (12%)

Query: 682  SSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741
            S P +R +FPE+W+W    +  R  ++ +  +PDS+T+W   G  IS + G+ +  T V+
Sbjct: 761  SKPEIRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADT-VK 816

Query: 742  LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINA 801
             + F+  F+ +N+PYSV+RGE+  L+ T++NY     +  V   K    + + TS E   
Sbjct: 817  AKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCV---KMSAVEGICTS-ESPV 872

Query: 802  TGHQQTLL-------VPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAE 854
              HQ T         V       V F + P  +G   I  +  +    + + + + V  E
Sbjct: 873  IDHQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEILVKTLRVVPE 932

Query: 855  GIEKSYSQSILLDLTDNRLQSTL---KTLSFSFPPNTVTGSERVQITAI-----GDVLGP 906
            G+++     + LD     +  T+   K   +  P + V  +E  +I ++     G++L  
Sbjct: 933  GVKRESYSGVTLD--PRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSA 990

Query: 907  SIN--GLASLIRMPYGCGEQNMINFAPNIYILDYLT--------------KKKQLTDNLK 950
             ++  G+  L  +P G  E  +++  P  Y+  YL               +K++L   LK
Sbjct: 991  VLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLK 1050

Query: 951  EKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVL 1010
            E  LS M         Y+  D S+S +     S STWL+AF LR   + + Y++ +QN +
Sbjct: 1051 EGMLSIMS--------YRNADYSYSVWKG--GSASTWLTAFALRVLGQVNKYVEQNQNSI 1100

Query: 1011 HRTYTWL-KGHQKSNGEFWDPGRVIHSELQG-----GNKSPVTLTAYIVTSLLGYRKYQP 1064
              +  WL + +Q  NG F +  +    +LQG       ++ + LTA+ V  +       P
Sbjct: 1101 CNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICP 1160

Query: 1065 NIDVQESIHFLES---EFSRGISDNYTLALITYALS--SVGSPKAKEALNMLTWRAEQEG 1119
             + +  ++   ++   E +      +TLA+  YALS      P+ +  ++ L   A  +G
Sbjct: 1161 LVKIDTALIKADNFLLENTLPAQSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKG 1220

Query: 1120 G---MQFWVSS----ESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQR 1172
                 +FW  +    +S + ++   R   +E  AYALL+       +   P+++WLS ++
Sbjct: 1221 NPPIYRFWKDNLQHKDSSVPNTGTARM--VETTAYALLTSLNLKDINYVNPVIKWLSEEQ 1278

Query: 1173 NSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPS--------------PL 1218
               GGF STQDT  A++ L+E++ L+   R ++ + V+     +              P+
Sbjct: 1279 RYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMTDKNFLGRPV 1338

Query: 1219 AVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQ-EAFDLDVAVKENKDDL 1277
             V+    + +S  GFG  +  ++V   V  + +S    S   + +  D++ +      + 
Sbjct: 1339 EVLLNDDLIVS-TGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGYGNS 1397

Query: 1278 NHVDLNVCTSFSGPGR------SGMALMEVNLLSGFMVPSEAI-SLSETVKKVEYDH--- 1327
            ++  +  C S+  P R      S  A+M+++L +G     E + +L E V ++  D+   
Sbjct: 1398 DYKRIVACASYK-PSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIK 1456

Query: 1328 -GKLNLYLDSVNETQF-CVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYN-SEVKL 1384
             G + L L+S+  + F CV       F+V     A+ ++ +Y+ P +Q    Y+ S +K+
Sbjct: 1457 DGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSNIKI 1516



 Score =  140 bits (352), Expect = 1e-32
 Identities = 169/660 (25%), Positives = 292/660 (44%), Gaps = 66/660 (10%)

Query: 28  FLVTAPGIIRPGGNVTIGVELL---EHCPSQVTVKAELLKTASNLTVSV-LEAEGVFEKG 83
           ++++AP I R G +  I +++    E   + +++K+   K  S  +  V L +E  F+  
Sbjct: 23  YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82

Query: 84  SFKTLTLPSLP--LNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYK 141
           +  T+    LP   N    +Y L V  +      FS S R+        +FI TDK +Y 
Sbjct: 83  AILTIQPKQLPGGQNPVSYVY-LEVVSKH-----FSKSKRMPITYDNGFLFIHTDKPVYT 136

Query: 142 PKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVIS-KTFQLSSHPI 200
           P Q VK R+ +L  D KP K    +   DP+ + +   + +   +G+IS   F++ S+P 
Sbjct: 137 PDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDM-VEEIDHIGIISFPDFKIPSNPR 195

Query: 201 LGDWSIQVQVNDQ---TYYQSFQVSEYVLPKFEVTLQTPLYCSM---NSKHLNGTITAKY 254
            G W+I+ +  +    T    F+V EYVLP F V+++ P Y  +   N K+   TI A+Y
Sbjct: 196 YGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIE-PEYNFIGYKNFKNFEITIKARY 254

Query: 255 TYGKPV-KGDVTLTF-LPLSFWGKKKNITK-----TFKINGSANFSFNDEEMKNVMDSSN 307
            Y K V + DV +TF +       +K + +     T  ING A  +F+ E       +  
Sbjct: 255 FYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSE------TAVK 308

Query: 308 GLSEY-LDLSSPGPVEILTTVTESVTGISRNVS-TNVFFKQHDYIIEFFDYTTVLKPSLN 365
            LS Y L+  +   + I  TV ES  G S       + +    Y +        LKP + 
Sbjct: 309 ELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIP 368

Query: 366 FTATVKVTRA-----DGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINY 420
           +   V+V  +      G  +TL  +      T+     T     S S  +  + V     
Sbjct: 369 YPIKVQVKDSLDQLVGGVPVTLNAQ------TIDVNQETSDLDPSKSVTRVDDGVASFVL 422

Query: 421 TVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVG 480
            +P SG   +EF +  D+ +L  +        ++A  SL  S S  YI      + + VG
Sbjct: 423 NLP-SGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSL--SQSYLYIDWTDNHKALLVG 479

Query: 481 SPFELVVSGNK----RLKELSYMVVSRGQLVAVGKQNS------TMFSLTPENSWTPKAC 530
               ++V+       ++   +Y+++S+G+++  G +           ++    +  P + 
Sbjct: 480 EHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSR 539

Query: 531 VIVYYI---EDDGEIISDVLKIPVQLVFKNKIKLYWS--KVKAEPSEKVSLRISVTQPDS 585
           ++VYYI   E   E++SD + + ++    N+++++ S       P + VSL ++ T  DS
Sbjct: 540 LLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQTVSLNMA-TGMDS 598

Query: 586 IVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDAN 645
            V + AVD +V  +       +E V   LE  + G   G  +N+  VF   GL  LT+AN
Sbjct: 599 WVALAAVDSAVYGVQRGAKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNAN 658


>gi|169218213 PREDICTED: similar to complement component C3, partial
            [Homo sapiens]
          Length = 1295

 Score =  180 bits (456), Expect = 1e-44
 Identities = 158/541 (29%), Positives = 258/541 (47%), Gaps = 55/541 (10%)

Query: 687  RKHFPETWIWLDTNMGYR-----IYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741
            R  FPE+W+W   ++          +   + + DSIT+W      +S+  G+     P E
Sbjct: 764  RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGI-CVADPFE 822

Query: 742  LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIE--KSDKFDILMTSNEI 799
            +   Q FFI L LPYSV+R E+  +   ++NY +   E+KV +E   +  F  L T+   
Sbjct: 823  VTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNY-RQNQELKVRVELLHNPAFCSLATTKR- 880

Query: 800  NATGHQQTLLVPSEDGATVLFPIRP--THLGEIPITVTALSPTASDAVTQMILVKAEGIE 857
                HQQT+ +P +   +V + I P  T L E+ +         SD V + + V  EGI 
Sbjct: 881  ---RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIR 937

Query: 858  KSYSQSI-LLDLTDNRLQSTLK------TLSFSFPPNTVTGSERVQITAIGDVLGPSING 910
             + + ++  LD      +   K       LS   P         +Q T +  +   +++ 
Sbjct: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997

Query: 911  --LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEK---ALSFMRQGYQREL 965
              L  LI  P GCGEQNMI   P +  + YL + +Q      EK   AL  +++GY ++L
Sbjct: 998  ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057

Query: 966  LYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWL-KGHQKSN 1024
             +++   +F+AF    P  STWL+A+V++ F  A   I ID  VL     WL    QK +
Sbjct: 1058 AFRQPSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115

Query: 1025 GEFWDPGRVIHSELQGG----NKSPVTLTAYIVTSLLGYR---KYQPNI---DVQESIHF 1074
            G F +   VIH E+ GG    N+  + LTA+++ SL   +   + Q N     + ++  F
Sbjct: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF 1175

Query: 1075 LESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDS 1134
            LE+ +   +  +YT+A+  YAL+ +G  K       LT   ++      W     +L   
Sbjct: 1176 LEANY-MNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR----WEDPGKQL--- 1227

Query: 1135 WQPRSLDIEVAAYALLSHFLQFQTSEGI-PIMRWLSRQRNSLGGFASTQDTTVALKALSE 1193
                  ++E  +YALL+  LQ +  + + P++RWL+ QR   GG+ STQ T +  +AL++
Sbjct: 1228 -----YNVEATSYALLA-LLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQ 1281

Query: 1194 F 1194
            +
Sbjct: 1282 Y 1282



 Score =  105 bits (263), Expect = 2e-22
 Identities = 126/535 (23%), Positives = 238/535 (44%), Gaps = 47/535 (8%)

Query: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQ-WLSQQSDLGVI 189
           +FIQTDK +Y P   V +RI T+     P   ++ + I++P+   ++Q  LS Q+ LGV+
Sbjct: 130 LFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVL 189

Query: 190 SKTFQLSSHPILGDWSIQVQVND---QTYYQSFQVSEYVLPKFEVTLQ--TPLYCSMNSK 244
             ++ +     +G W I+    +   Q +   F+V EYVLP FEV ++     Y   N K
Sbjct: 190 PLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEK 249

Query: 245 HLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFK----INGSANFSFNDEEMK 300
            L  TITA++ YGK V+G   + F  +    ++ ++ ++ K     +GS     +    K
Sbjct: 250 GLEVTITARFLYGKKVEGTAFVIF-GIQDGEQRISLPESLKRIPIEDGSGEVVLS---RK 305

Query: 301 NVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVL 360
            ++D    L    DL         T +  S + + +   + +      Y I F       
Sbjct: 306 VLLDGVQNLRAE-DLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYF 364

Query: 361 KPSLNFTATVKVTRADGN---QLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQK 417
           KP + F   V VT  DG+   ++ +  +  + V ++TQ +     S +   +QK      
Sbjct: 365 KPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQK-----P 419

Query: 418 INYTVPQSGTFKIEFPILEDSSE-LQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDEN 476
           ++ TV    T K E    E ++  +Q   Y     S+  +H    S  +T ++     E 
Sbjct: 420 LSITV---RTKKQELSEAEQATRTMQALPYSTVGNSNNYLH---LSVLRTELR---PGET 470

Query: 477 IKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGK------QNSTMFSLTPENSWTPKAC 530
           + V     +  +   +++  +Y+++++G+L+  G+      Q+  +  L+    + P   
Sbjct: 471 LNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFR 530

Query: 531 VIVYY----IEDDGEIISDVLKIPVQ--LVFKNKIKLYWSKVKAE-PSEKVSLRISVTQP 583
           ++ YY         E+++D + + V+   V    +K   S+ +   P ++++L+I     
Sbjct: 531 LVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHG 590

Query: 584 DSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638
             +V +VAVDK V ++N  N +T   +   +E  + G   G   +   VF + GL
Sbjct: 591 ARVV-LVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGL 644


>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
          Length = 750

 Score =  177 bits (450), Expect = 5e-44
 Identities = 141/500 (28%), Positives = 228/500 (45%), Gaps = 74/500 (14%)

Query: 517 FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSL 576
           F L+      P A + VY +   GEI++D ++  V   FK+K+ + +S  +  P    SL
Sbjct: 146 FPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASL 205

Query: 577 RISVTQPDSIVGIVAVDKSVNLMNASNDITME---NVVHELELYNTGYY----------- 622
            +    P     + AVD +V L+ +   ++ E   N+V  +E Y   Y+           
Sbjct: 206 YLQAA-PVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDP 264

Query: 623 ----LGMFMNS--------------FAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERF 664
                 MF N               + + +  GL V T+ +  K  +  +       +  
Sbjct: 265 CIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLPLPKPL 324

Query: 665 MEENEG----HIVDIHDFSLGSSPH------------VRKHFPETWIWLDTNMGYRIYQE 708
             E E     H V     S G                VR +FPETW+W   ++       
Sbjct: 325 YLETENYGPMHSVPSRIASSGIRGENADYVEQAIIQTVRTNFPETWMWDLVSVDSSGSAN 384

Query: 709 FEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEI 768
               +PD+IT W A+GF ++ D+G G+++T   L+  QPFFI +  P+SV++ E+F L +
Sbjct: 385 LSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVSQPFFIEIASPFSVVQNEQFDLIV 443

Query: 769 TIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLG 828
             F+YL    E+ V +E+S  ++  + + +IN +      ++ +    T ++ I P  LG
Sbjct: 444 NAFSYLNTCVEISVQVEESQNYEANINTWKINGSE-----VIQAGGRKTNIWTIIPKKLG 498

Query: 829 EIPITVTALSPTAS---------------DAVTQMILVKAEGIEKSYSQSILLDLTDNRL 873
           ++ ITV A S  +S               D V +  LV+ EGIEK  +QS L+  T+   
Sbjct: 499 KVNITVVAESKQSSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEKERTQSFLI-CTEGAK 557

Query: 874 QSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNI 933
            S    L    P + V GS R   T +GD+LG ++  L  +++MPYG GEQN    A + 
Sbjct: 558 ASKQGVL--DLPNDVVEGSARGFFTVVGDILGLAMQNLV-VLQMPYGGGEQNAALLASDT 614

Query: 934 YILDYLTKKKQLTDNLKEKA 953
           Y+LDYL   +QLT+ ++ KA
Sbjct: 615 YVLDYLKSTEQLTEEVQSKA 634


>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
           sapiens]
          Length = 278

 Score = 87.4 bits (215), Expect = 9e-17
 Identities = 40/117 (34%), Positives = 71/117 (60%), Gaps = 1/117 (0%)

Query: 686 VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAF 745
           VR +FPETW+W   ++           +PD+IT W A+GF ++ D+G G+++T   L+  
Sbjct: 67  VRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTT-LEVS 125

Query: 746 QPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINAT 802
           QPFFI +  P+SV++ E+F L + +F+Y     E+ V +E+S  ++  + + +IN +
Sbjct: 126 QPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANINTWKINGS 182


>gi|239758130 PREDICTED: similar to complement component 4B (Childo
            blood group), partial [Homo sapiens]
          Length = 666

 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 76/254 (29%), Positives = 111/254 (43%), Gaps = 32/254 (12%)

Query: 989  SAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQG---GNKSP 1045
            +AFVL+    A   +   +  L  T  WL   Q+++G F D   VIH  +QG   GN   
Sbjct: 1    TAFVLKVLSLAQEQVGGSREKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDET 60

Query: 1046 VTLTAYIVTSL-----------LGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITY 1094
            V LTA++  +L               K +    + ++  FL  + S G+   +  A+  Y
Sbjct: 61   VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAY 120

Query: 1095 ALSSVGSPKAKE--ALNMLTWRAEQEGGMQFWVSSESKLSDSWQPR-------------- 1138
            AL+   +P      A N L   A++ G   +W S     S++  P               
Sbjct: 121  ALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAP 180

Query: 1139 SLDIEVAAYALLSHFLQFQTSE-GIPIMRWLSRQRNSLGGFASTQDTTVALKALSEF-AA 1196
            +L IE  AYALL   L    +E       WL+RQ +  GGF STQDT +AL ALS +  A
Sbjct: 181  ALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIA 240

Query: 1197 LMNTERTNIQVTVT 1210
               TE   + VT++
Sbjct: 241  SHTTEERGLNVTLS 254



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 47/142 (33%), Positives = 67/142 (47%), Gaps = 12/142 (8%)

Query: 1269 AVKENKDDLNHVDLNVCTSFSGP-GRSGMALMEVNLLSGFMVP----SEAISLSET-VKK 1322
            A K  ++  + V   VC   +G  G SGMA+ +V LLSGF        +  SLS+  V  
Sbjct: 377  APKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSH 436

Query: 1323 VEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEV 1382
             E +   + LY DSV  ++ CV   AV+   V   Q AS ++ DYY P R+    Y +  
Sbjct: 437  FETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPS 496

Query: 1383 K------LSSCDLCSDVQGCRP 1398
            K      L S ++C   +G  P
Sbjct: 497  KSRLLATLCSAEVCQCAEGKCP 518


>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
           blood group) [Homo sapiens]
          Length = 270

 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 54/198 (27%), Positives = 95/198 (47%), Gaps = 14/198 (7%)

Query: 122 LSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLS 181
           L F ++R  +F+QTD+ +Y P Q V++R+  L    +P   ++ +++++     +++   
Sbjct: 52  LLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRK-KE 110

Query: 182 QQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQS---FQVSEYVLPKFEVTLQTP-- 236
                 +    F +      G W I  + +D     S   F+V +YVLP FEV + TP  
Sbjct: 111 VYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKI-TPGK 169

Query: 237 LYCSMNSKHLNG---TITAKYTYGKPVKGDVTLTFLPLSFWGKKKNI----TKTFKINGS 289
            Y      HL+     I A+Y YGKPV+G   + F  L   GKK       ++T  +NG 
Sbjct: 170 PYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQ 229

Query: 290 ANFSFNDEEMKNVMDSSN 307
           ++ S +  E ++ ++  N
Sbjct: 230 SHISLSKAEFQDALEKLN 247


>gi|169214179 PREDICTED: similar to complement component 3 [Homo
            sapiens]
          Length = 390

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 45/193 (23%), Positives = 83/193 (43%), Gaps = 27/193 (13%)

Query: 1228 ISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVK-------ENKDDLNHV 1280
            ++A G G     +  +Y+ KA       +       FDL V +K         +D  N +
Sbjct: 59   VTAEGKGQGTLSVVTMYHAKAKDQLTCNK-------FDLKVTIKPAPETEKRPQDAKNTM 111

Query: 1281 DLNVCTSFSGPGRSGMALMEVNLLSGFMVPSE-----AISLSETVKKVEY-----DHGKL 1330
             L +CT + G   + M+++++++++GF   ++     A  +   + K E      D   L
Sbjct: 112  ILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTL 171

Query: 1331 NLYLDSVNETQ-FCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCD- 1388
             +YLD V+ ++  C+     + F V   Q  +V +  YY       R Y+ E +    + 
Sbjct: 172  IIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNK 231

Query: 1389 LCSDVQGCRPCED 1401
            LC D + CR  E+
Sbjct: 232  LCRD-ELCRCAEE 243


>gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sapiens]
          Length = 189

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 37/135 (27%), Positives = 61/135 (45%), Gaps = 20/135 (14%)

Query: 1068 VQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEAL-NMLTWRAEQEGGMQFWVS 1126
            ++ ++  LE+    G+++ Y  A++ YA +  G  K  E+L   L   A +   + +W  
Sbjct: 50   LRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYWER 109

Query: 1127 SESKLSDS------WQPRSLDIEVAAYALLSHFLQFQTSEGIP-------IMRWLSRQRN 1173
                 ++       W P S   E + Y LL+       S  IP       I++WL++Q N
Sbjct: 110  ERKPKTEEFPSFIPWAP-SAQTEKSCYVLLAVI-----SRKIPDLTYASKIVQWLAQQMN 163

Query: 1174 SLGGFASTQDTTVAL 1188
            S GGF+S Q   V L
Sbjct: 164  SHGGFSSNQVINVGL 178


>gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo
           sapiens]
          Length = 261

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 1/94 (1%)

Query: 517 FSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSL 576
           F L+      P A + VY +   GEI++D ++  V   FK+K+ + +S  +  P    SL
Sbjct: 146 FPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASL 205

Query: 577 RISVTQPDSIVGIVAVDKSVNLMNASNDITMENV 610
            +    P     + AVD++V L+ +   ++ E+V
Sbjct: 206 CLQAA-PVLFCALRAVDRNVLLLKSEQQLSAESV 238


>gi|239755748 PREDICTED: ovostatin [Homo sapiens]
          Length = 257

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 45/167 (26%), Positives = 66/167 (39%), Gaps = 26/167 (15%)

Query: 1223 PTAVNISANGFGFAICQLNVVYNV----KASGSSRRRRSIQNQE--AFDLDVAVKENKDD 1276
            P    +   G G    Q  + YNV    KASG S     ++N    AFDL V +K     
Sbjct: 99   PGQYTVDVEGHGCTFIQATLKYNVLLPKKASGFSLSLEIVKNYSSTAFDLTVTLK----- 153

Query: 1277 LNHVDLNVCTSFSG-PGRSGMALMEVNLLSGFMVPSEAISLSET---VKKVEYDHGKLNL 1332
                       ++G   +S M +++V +LSGF     +I   E    V K E  +  +  
Sbjct: 154  -----------YTGIRNKSSMVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLF 202

Query: 1333 YLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYN 1379
            YL++             ++  V N Q A   + DYYE    A+  YN
Sbjct: 203  YLENGFGRADSFPFSVEQSNLVFNIQPAPAMVYDYYEKEEYALAFYN 249


>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
           sapiens]
          Length = 506

 Score = 34.7 bits (78), Expect = 0.67
 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 6/117 (5%)

Query: 833 TVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGS 892
           TV  L P    AVT++  +K E IEK +   + LD T    Q+ +K +     P +    
Sbjct: 216 TVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQR--QNVVKPIDNPPHPGSTKPL 273

Query: 893 ERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNL 949
           ++V I   G+++       ++    P    E N IN A  I      +KK    D+L
Sbjct: 274 KKVIIEETGNLIQTIDVPDSTTAAAP----ENNPINLANVIAATGTTSKKNSSQDDL 326


>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 34.7 bits (78), Expect = 0.67
 Identities = 32/117 (27%), Positives = 50/117 (42%), Gaps = 6/117 (5%)

Query: 833 TVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGS 892
           TV  L P    AVT++  +K E IEK +   + LD T    Q+ +K +     P +    
Sbjct: 375 TVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQR--QNVVKPIDNPPHPGSTKPL 432

Query: 893 ERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNL 949
           ++V I   G+++       ++    P    E N IN A  I      +KK    D+L
Sbjct: 433 KKVIIEETGNLIQTIDVPDSTTAAAP----ENNPINLANVIAATGTTSKKNSSQDDL 485


>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
          Length = 727

 Score = 33.1 bits (74), Expect = 2.0
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 15/98 (15%)

Query: 578 ISVTQPDSIVGIVAVDKSVNLMNASND--------ITMENVVHELELYNTGYYLGMFMNS 629
           +SV  PD I  + + + ++   N   D         TMEN +H    Y+ G ++G+   S
Sbjct: 450 LSVWFPDVIKPLQSDEYALLTRNVERDKYANFTINFTMENQIHTGMEYDNGRFIGVKFKS 509

Query: 630 F----AVFQECGLWVLTDANL---TKDYIDGVYDNAEY 660
                +VF+ C    +T  N       +ID V+DN ++
Sbjct: 510 VTFKDSVFKSCTFEDVTSVNTYFKNCTFIDTVFDNTDF 547


>gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]
          Length = 95

 Score = 32.7 bits (73), Expect = 2.6
 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 1296 MALMEVNLLSGFMVPSEAISLSET---VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNF 1352
            M +++V +LSGF     +I   E    V K E  +  +  YL++             ++ 
Sbjct: 1    MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60

Query: 1353 KVSNTQDASVSIVDYYEPRRQAVRSYN 1379
             V N Q A   + DYYE    A+  YN
Sbjct: 61   LVFNIQPAPAMVYDYYEKEEYALAFYN 87


>gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sapiens]
          Length = 95

 Score = 32.7 bits (73), Expect = 2.6
 Identities = 24/87 (27%), Positives = 37/87 (42%), Gaps = 3/87 (3%)

Query: 1296 MALMEVNLLSGFMVPSEAISLSET---VKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNF 1352
            M +++V +LSGF     +I   E    V K E  +  +  YL++             ++ 
Sbjct: 1    MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60

Query: 1353 KVSNTQDASVSIVDYYEPRRQAVRSYN 1379
             V N Q A   + DYYE    A+  YN
Sbjct: 61   LVFNIQPAPAMVYDYYEKEEYALAFYN 87


>gi|89264696 angiopoietin-like 4 protein isoform b precursor [Homo
           sapiens]
          Length = 368

 Score = 32.0 bits (71), Expect = 4.4
 Identities = 42/164 (25%), Positives = 58/164 (35%), Gaps = 27/164 (16%)

Query: 1   MQGPPLLTAAHLLCVCTAALAVAPG-------PRFLVTAPGIIRPGGNVTIGVELLEHCP 53
           M G P   AA +LC  TA L  A G       PRF       +   G + +G  L EH  
Sbjct: 1   MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREH-- 58

Query: 54  SQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDE 113
                 AE  ++  +     L A G   +G+  +  LP  P              R   E
Sbjct: 59  ------AERTRSQLSALERRLSACGSACQGTEGSTDLPLAP------------ESRVDPE 100

Query: 114 ILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDF 157
           +L S  T+L  +  RI           +  ++   RI  L S F
Sbjct: 101 VLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQF 144


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,229,333
Number of Sequences: 37866
Number of extensions: 2220617
Number of successful extensions: 5295
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 5082
Number of HSP's gapped (non-prelim): 85
length of query: 1428
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1313
effective length of database: 13,892,928
effective search space: 18241414464
effective search space used: 18241414464
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.