Search of human proteins with 22726201

Search of human proteins with 22726201

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22726201 inositol polyphosphate multikinase [Homo sapiens]
         (416 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22726201 inositol polyphosphate multikinase [Homo sapiens]         852   0.0  
gi|55769520 inositol hexaphosphate kinase 2 isoform a [Homo sapi...    95   1e-19
gi|56237025 inositol hexaphosphate kinase 2 isoform a [Homo sapi...    95   1e-19
gi|55769518 inositol hexakisphosphate kinase 1 isoform 2 [Homo s...    95   1e-19
gi|23510335 inositol hexakisphosphate kinase 1 isoform 1 [Homo s...    95   1e-19
gi|218777830 inositol hexakisphosphate kinase 3 [Homo sapiens]         86   8e-17
gi|55769530 inositol hexakisphosphate kinase 3 [Homo sapiens]          86   8e-17
gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo sapi...    44   3e-04
gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens]     36   0.056
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        35   0.13 
gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens]     34   0.28 
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 34   0.28 
gi|237681069 spatacsin isoform 2 [Homo sapiens]                        33   0.37 
gi|110671314 protection of telomeres 1 isoform 4 [Homo sapiens]        33   0.48 
gi|98991776 protection of telomeres 1 isoform 1 [Homo sapiens]         33   0.48 
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     33   0.48 
gi|5174545 myocyte enhancer factor 2D [Homo sapiens]                   32   1.1  
gi|5174731 translin-associated factor X [Homo sapiens]                 32   1.1  
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         32   1.4  
gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo sa...    31   1.8  
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    31   1.8  
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    31   1.8  
gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo s...    31   1.8  
gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo s...    31   1.8  
gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo s...    31   1.8  
gi|239755532 PREDICTED: similar to hCG1990723 [Homo sapiens]           31   1.8  
gi|239750002 PREDICTED: hypothetical protein XP_002347250 [Homo ...    31   1.8  
gi|239744313 PREDICTED: hypothetical protein XP_002343115 [Homo ...    31   1.8  
gi|37594444 zinc finger, MYND domain-containing 10 [Homo sapiens]      31   2.4  
gi|66346708 membrane associated guanylate kinase, WW and PDZ dom...    31   2.4  

>gi|22726201 inositol polyphosphate multikinase [Homo sapiens]
          Length = 416

 Score =  852 bits (2201), Expect = 0.0
 Identities = 416/416 (100%), Positives = 416/416 (100%)

Query: 1   MATEPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGK 60
           MATEPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGK
Sbjct: 1   MATEPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGK 60

Query: 61  DKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELRKYLPKYYGIWSPP 120
           DKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELRKYLPKYYGIWSPP
Sbjct: 61  DKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELRKYLPKYYGIWSPP 120

Query: 121 TAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLG 180
           TAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLG
Sbjct: 121 TAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEEIGFLVLG 180

Query: 181 MRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWF 240
           MRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWF
Sbjct: 181 MRVYHVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWF 240

Query: 241 ENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSS 300
           ENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSS
Sbjct: 241 ENQKQLNFYASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDTEVLEYNNNFHVLSS 300

Query: 301 TANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLS 360
           TANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLS
Sbjct: 301 TANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLS 360

Query: 361 QLEKVFYHLPTGCQEIAEVEVRMIDFAHVFPSNTIDEGYVYGLKHLISVLRSILDN 416
           QLEKVFYHLPTGCQEIAEVEVRMIDFAHVFPSNTIDEGYVYGLKHLISVLRSILDN
Sbjct: 361 QLEKVFYHLPTGCQEIAEVEVRMIDFAHVFPSNTIDEGYVYGLKHLISVLRSILDN 416


>gi|55769520 inositol hexaphosphate kinase 2 isoform a [Homo
           sapiens]
          Length = 426

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 46/139 (33%), Positives = 81/139 (58%), Gaps = 2/139 (1%)

Query: 127 YLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEE--IGFLVLGMRVY 184
           ++ LE++T ++  PC++D+K+G + +   AS EK   Q+ K        IG  V GM+VY
Sbjct: 203 FILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVY 262

Query: 185 HVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQK 244
              S      N+++GR L+ +  K+ + +FFHNG  LR++ +   ++K+ ++    E Q+
Sbjct: 263 QAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLRRELLGPVLKKLTELKAVLERQE 322

Query: 245 QLNFYASSLLFVYEGSSQP 263
              FY+SSLL +Y+G  +P
Sbjct: 323 SYRFYSSSLLVIYDGKERP 341



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 9/46 (19%)

Query: 377 AEVEVRMIDFAH----VFPSNTI-----DEGYVYGLKHLISVLRSI 413
           + V+VRMIDFAH    ++  +T+     D GY++GL+ LI ++  I
Sbjct: 375 SSVDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLIDIVTEI 420



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 20/71 (28%)

Query: 48  PLSHQVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELR 107
           P  HQV GH        +L+  + T+ K     P  PRE +FY  + A         E+R
Sbjct: 21  PFVHQVGGHSC------VLRFNETTLCK-----PLVPREHQFYETLPA---------EMR 60

Query: 108 KYLPKYYGIWS 118
           K+ P+Y G+ S
Sbjct: 61  KFTPQYKGVVS 71


>gi|56237025 inositol hexaphosphate kinase 2 isoform a [Homo
           sapiens]
          Length = 426

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 46/139 (33%), Positives = 81/139 (58%), Gaps = 2/139 (1%)

Query: 127 YLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEE--IGFLVLGMRVY 184
           ++ LE++T ++  PC++D+K+G + +   AS EK   Q+ K        IG  V GM+VY
Sbjct: 203 FILLENLTSRYEVPCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVY 262

Query: 185 HVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQK 244
              S      N+++GR L+ +  K+ + +FFHNG  LR++ +   ++K+ ++    E Q+
Sbjct: 263 QAGSGQLMFMNKYHGRKLSVQGFKEALFQFFHNGRYLRRELLGPVLKKLTELKAVLERQE 322

Query: 245 QLNFYASSLLFVYEGSSQP 263
              FY+SSLL +Y+G  +P
Sbjct: 323 SYRFYSSSLLVIYDGKERP 341



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 9/46 (19%)

Query: 377 AEVEVRMIDFAH----VFPSNTI-----DEGYVYGLKHLISVLRSI 413
           + V+VRMIDFAH    ++  +T+     D GY++GL+ LI ++  I
Sbjct: 375 SSVDVRMIDFAHTTCRLYGEDTVVHEGQDAGYIFGLQSLIDIVTEI 420



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 20/71 (28%)

Query: 48  PLSHQVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLELR 107
           P  HQV GH        +L+  + T+ K     P  PRE +FY  + A         E+R
Sbjct: 21  PFVHQVGGHSC------VLRFNETTLCK-----PLVPREHQFYETLPA---------EMR 60

Query: 108 KYLPKYYGIWS 118
           K+ P+Y G+ S
Sbjct: 61  KFTPQYKGVVS 71


>gi|55769518 inositol hexakisphosphate kinase 1 isoform 2 [Homo
           sapiens]
          Length = 276

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 49/148 (33%), Positives = 82/148 (55%), Gaps = 2/148 (1%)

Query: 127 YLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSK--YPLMEEIGFLVLGMRVY 184
           +L LE+V H F  PC++D+K+G + +   AS+EK  +Q+ K        +G  V GM+VY
Sbjct: 42  FLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVY 101

Query: 185 HVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQK 244
            + +  Y   N++YGR L+ E  ++ + ++ HNG  LR+D     + K+  +    E Q 
Sbjct: 102 QLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQA 161

Query: 245 QLNFYASSLLFVYEGSSQPTTTKLNDRT 272
              FY+SSLL +Y+G      + L+ R+
Sbjct: 162 SYRFYSSSLLVIYDGKECRAESCLDRRS 189



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 9/47 (19%)

Query: 378 EVEVRMIDFAHVF-----PSNTI----DEGYVYGLKHLISVLRSILD 415
           +V+VRMIDFAH          T+    D GYV+GL++LIS++  + D
Sbjct: 227 KVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQMRD 273


>gi|23510335 inositol hexakisphosphate kinase 1 isoform 1 [Homo
           sapiens]
          Length = 441

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 49/148 (33%), Positives = 82/148 (55%), Gaps = 2/148 (1%)

Query: 127 YLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSK--YPLMEEIGFLVLGMRVY 184
           +L LE+V H F  PC++D+K+G + +   AS+EK  +Q+ K        +G  V GM+VY
Sbjct: 207 FLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVY 266

Query: 185 HVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQK 244
            + +  Y   N++YGR L+ E  ++ + ++ HNG  LR+D     + K+  +    E Q 
Sbjct: 267 QLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQA 326

Query: 245 QLNFYASSLLFVYEGSSQPTTTKLNDRT 272
              FY+SSLL +Y+G      + L+ R+
Sbjct: 327 SYRFYSSSLLVIYDGKECRAESCLDRRS 354



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 9/47 (19%)

Query: 378 EVEVRMIDFAHVF-----PSNTI----DEGYVYGLKHLISVLRSILD 415
           +V+VRMIDFAH          T+    D GYV+GL++LIS++  + D
Sbjct: 392 KVDVRMIDFAHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQMRD 438


>gi|218777830 inositol hexakisphosphate kinase 3 [Homo sapiens]
          Length = 410

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 41/139 (29%), Positives = 76/139 (54%), Gaps = 2/139 (1%)

Query: 127 YLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEE--IGFLVLGMRVY 184
           +L LE+V  ++  PC++D+K+G + +   AS EK  + + K        +G  + GM+VY
Sbjct: 198 FLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQVY 257

Query: 185 HVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQK 244
                 +  ++++YGR L+ E  +  + +F HNG  LR++ +   + ++  +L    +Q 
Sbjct: 258 QTDKKYFLCKDKYYGRKLSVEGFRQALYQFLHNGSHLRRELLEPILHQLRALLSVIRSQS 317

Query: 245 QLNFYASSLLFVYEGSSQP 263
              FY+SSLL +Y+G   P
Sbjct: 318 SYRFYSSSLLVIYDGQEPP 336



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 18/47 (38%), Positives = 30/47 (63%), Gaps = 9/47 (19%)

Query: 376 IAEVEVRMIDFAHV-----FPSNTI----DEGYVYGLKHLISVLRSI 413
           + +V++RMIDFAH      +  +T     D GY++GL++LI +L+ I
Sbjct: 360 LTKVDIRMIDFAHTTYKGYWNEHTTYDGPDPGYIFGLENLIRILQDI 406


>gi|55769530 inositol hexakisphosphate kinase 3 [Homo sapiens]
          Length = 410

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 41/139 (29%), Positives = 76/139 (54%), Gaps = 2/139 (1%)

Query: 127 YLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLMEE--IGFLVLGMRVY 184
           +L LE+V  ++  PC++D+K+G + +   AS EK  + + K        +G  + GM+VY
Sbjct: 198 FLLLENVVSQYTHPCVLDLKMGTRQHGDDASEEKKARHMRKCAQSTSACLGVRICGMQVY 257

Query: 185 HVHSDSYETENQHYGRSLTKETIKDGVSRFFHNGYCLRKDAVAASIQKIEKILQWFENQK 244
                 +  ++++YGR L+ E  +  + +F HNG  LR++ +   + ++  +L    +Q 
Sbjct: 258 QTDKKYFLCKDKYYGRKLSVEGFRQALYQFLHNGSHLRRELLEPILHQLRALLSVIRSQS 317

Query: 245 QLNFYASSLLFVYEGSSQP 263
              FY+SSLL +Y+G   P
Sbjct: 318 SYRFYSSSLLVIYDGQEPP 336



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 18/47 (38%), Positives = 30/47 (63%), Gaps = 9/47 (19%)

Query: 376 IAEVEVRMIDFAHV-----FPSNTI----DEGYVYGLKHLISVLRSI 413
           + +V++RMIDFAH      +  +T     D GY++GL++LI +L+ I
Sbjct: 360 LTKVDIRMIDFAHTTYKGYWNEHTTYDGPDPGYIFGLENLIRILQDI 406


>gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo
           sapiens]
          Length = 946

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 46/200 (23%), Positives = 88/200 (44%), Gaps = 43/200 (21%)

Query: 98  CFDGVLLE-LRKYLPKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSY---- 152
           C D ++++ LR ++P Y+G         + Y +++D+   F+ PC+MD K+G ++Y    
Sbjct: 699 CLDRLMVDVLRPFVPAYHG---DVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEE 755

Query: 153 ---------------------DPFA--SSEKIQQQVSKYPLME----EIGFLVLGMRVYH 185
                                DP A    EK Q+ V+K   M+          LG R+  
Sbjct: 756 LTKARKKPSLRKDMYQKMIEVDPEAPTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEG 815

Query: 186 VHSDSYETENQHYGRSLTKETIKDGVSRFF---HNGYCLRKDAVAASIQKIEKILQWFEN 242
           +  +   T N+ + ++ T+E + +    F    HN     +D + A I+   ++  +F+ 
Sbjct: 816 IKKED-GTVNRDFKKTKTREQVTEAFREFTKGNHNILIAYRDRLKA-IRTTLEVSPFFKC 873

Query: 243 QKQLNFYASSLLFVYEGSSQ 262
            + +    SSLLF+++   Q
Sbjct: 874 HEVI---GSSLLFIHDKKEQ 890


>gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens]
          Length = 461

 Score = 36.2 bits (82), Expect = 0.056
 Identities = 35/154 (22%), Positives = 67/154 (43%), Gaps = 32/154 (20%)

Query: 52  QVAGHMYGKDKVGILQHPDGTVLKQLQPPPRGPRELEFYNMVYAADCFDGVLLE-LRKYL 110
           Q+AGH       G      G +LK+   P R               C   ++ + LR  +
Sbjct: 190 QLAGHTGSFKAAGT----SGLILKRCSEPERY--------------CLARLMADALRGCV 231

Query: 111 PKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPL 170
           P ++G+        + YL+L+D+   F+ PC++D K+G ++Y      E++ +   +  L
Sbjct: 232 PAFHGVVE---RDGESYLQLQDLLDGFDGPCVLDCKMGVRTY----LEEELTKARERPKL 284

Query: 171 MEEIGFLVLGMRVYHVHSDSYETENQHYGRSLTK 204
            +++   +L +           TE +H  R++TK
Sbjct: 285 RKDMYKKMLAV------DPEAPTEEEHAQRAVTK 312


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 15/36 (41%), Positives = 18/36 (50%)

Query: 4    EPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGR 39
            E PSP     PG P  R  P   + P+GTP P G +
Sbjct: 1258 ESPSPSHQARPGVPPPRGVPPARAQPDGTPSPGGSK 1293


>gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens]
          Length = 683

 Score = 33.9 bits (76), Expect = 0.28
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)

Query: 106 LRKYLPKYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSY 152
           LR ++P YYG+          + ++ED+   F  P IMD K+G ++Y
Sbjct: 449 LRPFVPAYYGM---VLQDGQTFNQMEDLLADFEGPSIMDCKMGSRTY 492


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 33.9 bits (76), Expect = 0.28
 Identities = 20/41 (48%), Positives = 22/41 (53%), Gaps = 6/41 (14%)

Query: 2   ATEP-PSPLRVEAPGP-----PEMRTSPAIESTPEGTPQPA 36
           A+EP P P    AP P     PE    PA ES PE TP+PA
Sbjct: 90  ASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPA 130



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 10/43 (23%)

Query: 2   ATEP-PSPLRVEAPGP---------PEMRTSPAIESTPEGTPQ 34
           ATEP P P    AP P         PE    PA+ES PE  P+
Sbjct: 98  ATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPE 140


>gi|237681069 spatacsin isoform 2 [Homo sapiens]
          Length = 2330

 Score = 33.5 bits (75), Expect = 0.37
 Identities = 45/194 (23%), Positives = 78/194 (40%), Gaps = 29/194 (14%)

Query: 229  SIQKIEKILQWFENQKQLNFYASSLL---FVYEGS---------SQPTTTKLNDRTLAEK 276
            S +  E  L W E Q+ LNF    LL    V+E S         +      L+ R LA  
Sbjct: 1862 SKETCENRLDWKE-QESLNFLIGRLLDDGCVHEASRVCRYFHFYNPDVALVLHCRALAS- 1919

Query: 277  FLSKGQLSDTEVLEYNNNFHVLSSTANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLK 336
                    +  + + +   H L  +A    E +    L ++++RH++++     SQT L+
Sbjct: 1920 -------GEASMEDLHPEIHALLQSAELLEEEAPDIPLRRVHSRHKQMFNPTEESQTFLQ 1972

Query: 337  VENLEQDNGWKSM-------SQEHLNGNVLSQLEKVFYHLPTGCQEIAEVEVRMIDFAHV 389
            +  L QD     M       S  H   +  ++L  + +H  T    +  + +R++  AH+
Sbjct: 1973 LTTLCQDRTLVGMKLLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGI-IRVLQAAHM 2031

Query: 390  FPSNTIDEGYVYGL 403
               N +     YGL
Sbjct: 2032 LTDNHLAPSEEYGL 2045


>gi|110671314 protection of telomeres 1 isoform 4 [Homo sapiens]
          Length = 503

 Score = 33.1 bits (74), Expect = 0.48
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 19/97 (19%)

Query: 250 ASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDT--------EVLEYNNNFHVLSST 301
           AS LL V++G+  P  +    R L +  + +G LS          ++L Y+N+ HV  S 
Sbjct: 46  ASFLLKVWDGTRTPFPSW---RVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSL 102

Query: 302 ANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVE 338
             G        S  ++Y+ H K+ +    +QT L +E
Sbjct: 103 KVG--------SFLRIYSLHTKLQSMNSENQTMLSLE 131


>gi|98991776 protection of telomeres 1 isoform 1 [Homo sapiens]
          Length = 634

 Score = 33.1 bits (74), Expect = 0.48
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 19/97 (19%)

Query: 250 ASSLLFVYEGSSQPTTTKLNDRTLAEKFLSKGQLSDT--------EVLEYNNNFHVLSST 301
           AS LL V++G+  P  +    R L +  + +G LS          ++L Y+N+ HV  S 
Sbjct: 177 ASFLLKVWDGTRTPFPSW---RVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSL 233

Query: 302 ANGKIESSVGKSLSKMYARHRKIYTKKHHSQTSLKVE 338
             G        S  ++Y+ H K+ +    +QT L +E
Sbjct: 234 KVG--------SFLRIYSLHTKLQSMNSENQTMLSLE 262


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 33.1 bits (74), Expect = 0.48
 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 5/64 (7%)

Query: 2   ATEPPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLS-HQVAGHMYGK 60
           A EPP P   + P PP+ +  P     P+  P P GG +R      P+S  +V  ++ G 
Sbjct: 206 AREPPLPPPPQPPAPPQQQQPP----PPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGS 261

Query: 61  DKVG 64
              G
Sbjct: 262 GGAG 265


>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
          Length = 521

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 1/37 (2%)

Query: 3   TEPPSPLRVEAPGPPEMRTSPAIESTP-EGTPQPAGG 38
           +EP SP R  +P PP     PA    P +G   PAGG
Sbjct: 440 SEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGG 476


>gi|5174731 translin-associated factor X [Homo sapiens]
          Length = 290

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 24/103 (23%), Positives = 41/103 (39%), Gaps = 6/103 (5%)

Query: 112 KYYGIWSPPTAPNDLYLKLEDVTHKFNKPCIMDVKIGQKSYDPFASSEKIQQQVSKYPLM 171
           K +G W     P D  L + D+T +  + CI  V  G     PF  S+ ++Q    +  +
Sbjct: 173 KQFGTWRLRVTPVDYLLGVADLTGELMRMCINSVGNGDID-TPFEVSQFLRQVYDGFSFI 231

Query: 172 EEIGFLVLGMRVYHVHSDSYETENQHY-----GRSLTKETIKD 209
              G   +  ++Y +     + EN  Y     G  + K  + D
Sbjct: 232 GNTGPYEVSKKLYTLKQSLAKVENACYALKVRGSEIPKHMLAD 274


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 29/85 (34%), Positives = 30/85 (35%), Gaps = 9/85 (10%)

Query: 5   PPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHM----YGK 60
           PP PL   A  PP   T P + ST  G    A G  R   G  P   Q   H     Y  
Sbjct: 261 PPPPLPGLATSPPFQLTKPGLWSTLHG---DAWGPER--KGSAPPERQEQRHSLPHPYPY 315

Query: 61  DKVGILQHPDGTVLKQLQPPPRGPR 85
                  HP G  L    PP  GPR
Sbjct: 316 PAPAYTAHPPGHRLVPAAPPGPGPR 340



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 9/49 (18%)

Query: 4  EPPSPLRVEAPGPPEMRTSPAIESTP-----EGTPQPAGGRLRFLNGCV 47
          +PP P    AP PP   +S    S P       TP+P  G+L  L+GCV
Sbjct: 53 QPPLP----APLPPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCV 97


>gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo
           sapiens]
          Length = 630

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 2   ATEPPSPLRVEAPGPPEMRTSPAIESTPEGTP 33
           A  PP+PL   A GPP  ++S  +   P+ TP
Sbjct: 374 AGSPPAPLAPSASGPPVCKSSEVLYERPQPTP 405


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 15/84 (17%)

Query: 5   PPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGKDKVG 64
           P SPL   AP PP+++  P  +  P+  PQP           +P   Q       +    
Sbjct: 393 PGSPLFTRAP-PPKLQPQPQPQPQPQSQPQPQ----------LPPQPQT----QPQTPTP 437

Query: 65  ILQHPDGTVLKQLQPPPRGPRELE 88
             QHP  T     + PP+ P ELE
Sbjct: 438 APQHPQQTWPPVNEGPPKPPTELE 461


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 15/84 (17%)

Query: 5   PPSPLRVEAPGPPEMRTSPAIESTPEGTPQPAGGRLRFLNGCVPLSHQVAGHMYGKDKVG 64
           P SPL   AP PP+++  P  +  P+  PQP           +P   Q       +    
Sbjct: 393 PGSPLFTRAP-PPKLQPQPQPQPQPQSQPQPQ----------LPPQPQT----QPQTPTP 437

Query: 65  ILQHPDGTVLKQLQPPPRGPRELE 88
             QHP  T     + PP+ P ELE
Sbjct: 438 APQHPQQTWPPVNEGPPKPPTELE 461


>gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo
           sapiens]
          Length = 618

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 2   ATEPPSPLRVEAPGPPEMRTSPAIESTPEGTP 33
           A  PP+PL   A GPP  ++S  +   P+ TP
Sbjct: 362 AGSPPAPLAPSASGPPVCKSSEVLYERPQPTP 393


>gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo
           sapiens]
          Length = 649

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 2   ATEPPSPLRVEAPGPPEMRTSPAIESTPEGTP 33
           A  PP+PL   A GPP  ++S  +   P+ TP
Sbjct: 362 AGSPPAPLAPSASGPPVCKSSEVLYERPQPTP 393


>gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 2   ATEPPSPLRVEAPGPPEMRTSPAIESTPEGTP 33
           A  PP+PL   A GPP  ++S  +   P+ TP
Sbjct: 374 AGSPPAPLAPSASGPPVCKSSEVLYERPQPTP 405


>gi|239755532 PREDICTED: similar to hCG1990723 [Homo sapiens]
          Length = 225

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 10/29 (34%), Positives = 20/29 (68%)

Query: 184 YHVHSDSYETENQHYGRSLTKETIKDGVS 212
           YH+H  ++ T +Q +GR+L +E +++  S
Sbjct: 89  YHIHHGAWTTAHQEHGRNLAEEVLQESAS 117


>gi|239750002 PREDICTED: hypothetical protein XP_002347250 [Homo
           sapiens]
          Length = 505

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 10/29 (34%), Positives = 20/29 (68%)

Query: 184 YHVHSDSYETENQHYGRSLTKETIKDGVS 212
           YH+H  ++ T +Q +GR+L +E +++  S
Sbjct: 369 YHIHHGAWTTAHQEHGRNLAEEVLQESAS 397


>gi|239744313 PREDICTED: hypothetical protein XP_002343115 [Homo
           sapiens]
          Length = 456

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 10/29 (34%), Positives = 20/29 (68%)

Query: 184 YHVHSDSYETENQHYGRSLTKETIKDGVS 212
           YH+H  ++ T +Q +GR+L +E +++  S
Sbjct: 320 YHIHHGAWTTAHQEHGRNLAEEVLQESAS 348


>gi|37594444 zinc finger, MYND domain-containing 10 [Homo sapiens]
          Length = 440

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 18/121 (14%)

Query: 279 SKGQLSDTEVLEYNNNFHVLSSTANGKIESSVGKSLSKMYARHRKIYT-----------K 327
           S+G     E LE  N   +L +T       S G+ + ++   H K+ T           K
Sbjct: 29  SEGWNQQHENLEKLNMQAILDATV------SQGEPIQELLVTHGKVPTLVEELIAVEMWK 82

Query: 328 KHHSQTSLKVENLEQDNGWKSMSQEHLNGNVLSQLEKVFYHLPTGCQEIAEVEVRMIDFA 387
           +       +VE+ +  N +      H   ++++ LE VF+H    C+   +  + ++D+ 
Sbjct: 83  QKVFPVFCRVEDFKPQNTFPIYMVVHHEASIINLLETVFFHKEV-CESAEDTVLDLVDYC 141

Query: 388 H 388
           H
Sbjct: 142 H 142


>gi|66346708 membrane associated guanylate kinase, WW and PDZ domain
           containing 1 isoform b [Homo sapiens]
          Length = 1256

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 8/80 (10%)

Query: 82  RGPRELEF----YNMVYAADCFD----GVLLELRKYLPKYYGIWSPPTAPNDLYLKLEDV 133
           R PRE E     YN +   +  D    G LLE+  Y   YYG   PP+ P    +   D 
Sbjct: 147 RSPREGEVPGVDYNFLTVKEFLDLEQSGTLLEVGTYEGNYYGTPKPPSQPVSGKVITTDA 206

Query: 134 THKFNKPCIMDVKIGQKSYD 153
            H              KSY+
Sbjct: 207 LHSLQSGSKQSTPKRTKSYN 226


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,395,927
Number of Sequences: 37866
Number of extensions: 854210
Number of successful extensions: 3828
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 3711
Number of HSP's gapped (non-prelim): 144
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.