Guide to the Human Genome
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Search of human proteins with 227116306

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|227116306 ret finger protein-like 2 isoform 3 [Homo sapiens]
         (288 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|227116308 ret finger protein-like 2 isoform 3 [Homo sapiens]       589   e-169
gi|227116306 ret finger protein-like 2 isoform 3 [Homo sapiens]       589   e-169
gi|148728184 ret finger protein-like 2 isoform 1 [Homo sapiens]       589   e-169
gi|227116303 ret finger protein-like 2 isoform 2 [Homo sapiens]       589   e-169
gi|149408135 ret finger protein-like 3 isoform 1 [Homo sapiens]       557   e-159
gi|5730013 ret finger protein-like 3 isoform 2 [Homo sapiens]         557   e-159
gi|149408130 ret finger protein-like 1 [Homo sapiens]                 533   e-152
gi|222446629 ret finger protein-like 4A [Homo sapiens]                325   3e-89
gi|5730009 ret finger protein [Homo sapiens]                          150   1e-36
gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo ...   149   2e-36
gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo...   149   2e-36
gi|153791360 ret finger protein-like 4B [Homo sapiens]                147   1e-35
gi|4557743 Mediterranean fever protein [Homo sapiens]                 145   3e-35
gi|222418658 butyrophilin, subfamily 3, member A1 isoform c [Hom...   145   4e-35
gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo...   145   4e-35
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             141   6e-34
gi|15208660 tripartite motif protein 21 [Homo sapiens]                140   1e-33
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]      134   7e-32
gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo...   134   7e-32
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ...   134   7e-32
gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precur...   134   9e-32
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             132   3e-31
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   131   6e-31
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   131   6e-31
gi|63054855 erythroblast membrane-associated protein precursor [...   126   2e-29
gi|19923536 erythroblast membrane-associated protein precursor [...   126   2e-29
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              125   3e-29
gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]   122   3e-28
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   122   3e-28
gi|37622899 ring finger protein 137 [Homo sapiens]                    119   4e-27

>gi|227116308 ret finger protein-like 2 isoform 3 [Homo sapiens]
          Length = 288

 Score =  589 bits (1519), Expect = e-169
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60
           MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK
Sbjct: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60

Query: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120
           IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS
Sbjct: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120

Query: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180
           GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL
Sbjct: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180

Query: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240
           TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT
Sbjct: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240

Query: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288
           FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK
Sbjct: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288


>gi|227116306 ret finger protein-like 2 isoform 3 [Homo sapiens]
          Length = 288

 Score =  589 bits (1519), Expect = e-169
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60
           MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK
Sbjct: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60

Query: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120
           IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS
Sbjct: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120

Query: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180
           GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL
Sbjct: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180

Query: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240
           TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT
Sbjct: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240

Query: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288
           FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK
Sbjct: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288


>gi|148728184 ret finger protein-like 2 isoform 1 [Homo sapiens]
          Length = 317

 Score =  589 bits (1519), Expect = e-169
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60
           MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK
Sbjct: 30  MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 89

Query: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120
           IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS
Sbjct: 90  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 149

Query: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180
           GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL
Sbjct: 150 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 209

Query: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240
           TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT
Sbjct: 210 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 269

Query: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288
           FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK
Sbjct: 270 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 317


>gi|227116303 ret finger protein-like 2 isoform 2 [Homo sapiens]
          Length = 378

 Score =  589 bits (1519), Expect = e-169
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60
           MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK
Sbjct: 91  MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 150

Query: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120
           IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS
Sbjct: 151 IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 210

Query: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180
           GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL
Sbjct: 211 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 270

Query: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240
           TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT
Sbjct: 271 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 330

Query: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288
           FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK
Sbjct: 331 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 378


>gi|149408135 ret finger protein-like 3 isoform 1 [Homo sapiens]
          Length = 317

 Score =  557 bits (1435), Expect = e-159
 Identities = 272/288 (94%), Positives = 278/288 (96%)

Query: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60
           MAALFQEASSCPVCSDYLEKPMSLECGC VCLKCINSLQKEPHGEDLLCCC SMVS++NK
Sbjct: 30  MAALFQEASSCPVCSDYLEKPMSLECGCTVCLKCINSLQKEPHGEDLLCCCCSMVSQRNK 89

Query: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120
           IR NRQLERL SHIKELEPKLKKILQMNPRMRKFQVDMTLDA+TANNFLLISDDLRSVRS
Sbjct: 90  IRPNRQLERLVSHIKELEPKLKKILQMNPRMRKFQVDMTLDADTANNFLLISDDLRSVRS 149

Query: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180
           G I QNRQDLAERFDVSVCILGSPRFTCGRH WEVDVGTSTEWDLGVCRESVH KG+IQL
Sbjct: 150 GLITQNRQDLAERFDVSVCILGSPRFTCGRHYWEVDVGTSTEWDLGVCRESVHCKGKIQL 209

Query: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240
           TTELGFWTVSLRDG RLSA+TVPLTFL VDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT
Sbjct: 210 TTELGFWTVSLRDGSRLSASTVPLTFLLVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 269

Query: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288
           FRSVSAEEPLRPFLAPS+PPNGDQGVLSICPLMNSGTTDAPVRPGEAK
Sbjct: 270 FRSVSAEEPLRPFLAPSIPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 317


>gi|5730013 ret finger protein-like 3 isoform 2 [Homo sapiens]
          Length = 288

 Score =  557 bits (1435), Expect = e-159
 Identities = 272/288 (94%), Positives = 278/288 (96%)

Query: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60
           MAALFQEASSCPVCSDYLEKPMSLECGC VCLKCINSLQKEPHGEDLLCCC SMVS++NK
Sbjct: 1   MAALFQEASSCPVCSDYLEKPMSLECGCTVCLKCINSLQKEPHGEDLLCCCCSMVSQRNK 60

Query: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120
           IR NRQLERL SHIKELEPKLKKILQMNPRMRKFQVDMTLDA+TANNFLLISDDLRSVRS
Sbjct: 61  IRPNRQLERLVSHIKELEPKLKKILQMNPRMRKFQVDMTLDADTANNFLLISDDLRSVRS 120

Query: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180
           G I QNRQDLAERFDVSVCILGSPRFTCGRH WEVDVGTSTEWDLGVCRESVH KG+IQL
Sbjct: 121 GLITQNRQDLAERFDVSVCILGSPRFTCGRHYWEVDVGTSTEWDLGVCRESVHCKGKIQL 180

Query: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240
           TTELGFWTVSLRDG RLSA+TVPLTFL VDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT
Sbjct: 181 TTELGFWTVSLRDGSRLSASTVPLTFLLVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240

Query: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288
           FRSVSAEEPLRPFLAPS+PPNGDQGVLSICPLMNSGTTDAPVRPGEAK
Sbjct: 241 FRSVSAEEPLRPFLAPSIPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288


>gi|149408130 ret finger protein-like 1 [Homo sapiens]
          Length = 317

 Score =  533 bits (1373), Expect = e-152
 Identities = 261/288 (90%), Positives = 269/288 (93%)

Query: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60
           MAALFQEASSCPVCSDYLEKPMSLECGCAVC KCINSLQKEPHGEDLLCCC SMVS+KNK
Sbjct: 30  MAALFQEASSCPVCSDYLEKPMSLECGCAVCFKCINSLQKEPHGEDLLCCCCSMVSQKNK 89

Query: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120
           IR + QLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDA+TANNFLLISDDLRSVRS
Sbjct: 90  IRPSWQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDADTANNFLLISDDLRSVRS 149

Query: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180
           G I QNRQDLAERFDVS+CILGSPRFTCGRH WEVDVGTSTEWDLGVCRESVHRKGRI L
Sbjct: 150 GCITQNRQDLAERFDVSICILGSPRFTCGRHYWEVDVGTSTEWDLGVCRESVHRKGRIHL 209

Query: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240
           TTE GFWTVSLRDG RLSA+TVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAE GSHVYT
Sbjct: 210 TTERGFWTVSLRDGSRLSASTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAEGGSHVYT 269

Query: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPVRPGEAK 288
           FRSVSAEEPL  F AP  PPNGD+ VLSICP++N GTTDAPV PGEAK
Sbjct: 270 FRSVSAEEPLHLFFAPPSPPNGDKSVLSICPVINPGTTDAPVHPGEAK 317


>gi|222446629 ret finger protein-like 4A [Homo sapiens]
          Length = 287

 Score =  325 bits (833), Expect = 3e-89
 Identities = 158/282 (56%), Positives = 207/282 (73%)

Query: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60
           MA  F++   CPVC   LE+ + L+CG A CL+C+NSLQKEP GE LLC   S+VS+K+ 
Sbjct: 1   MAEHFKQIIRCPVCLKDLEEAVQLKCGYACCLQCLNSLQKEPDGEGLLCRFCSVVSQKDD 60

Query: 61  IRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRS 120
           I+   +L  L S IKELEPKLK +L MNPRMRKFQVDMT D +TANN+L+IS+DLRS RS
Sbjct: 61  IKPKYKLRALVSIIKELEPKLKSVLTMNPRMRKFQVDMTFDVDTANNYLIISEDLRSFRS 120

Query: 121 GRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQL 180
           G + QNR++ AERFD ++C+LG+PRFT GRH WEVDVGTS  WD+GVC+ESV+R+G+I L
Sbjct: 121 GDLSQNRKEQAERFDTALCVLGTPRFTSGRHYWEVDVGTSQVWDVGVCKESVNRQGKIVL 180

Query: 181 TTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYT 240
           ++E GF TV  R+G   +A+TVP+T L+V  +L RVGIFLD+GM++++F++   G H+YT
Sbjct: 181 SSEHGFLTVGCREGKVFAASTVPMTPLWVSPQLHRVGIFLDVGMRSIAFYNVSDGCHIYT 240

Query: 241 FRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGTTDAPV 282
           F  +   EP RPF A       DQ +LSIC ++N     APV
Sbjct: 241 FIEIPVCEPWRPFFAHKRGSQDDQSILSICSVINPSAASAPV 282


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  150 bits (380), Expect = 1e-36
 Identities = 81/205 (39%), Positives = 118/205 (57%), Gaps = 1/205 (0%)

Query: 68  ERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRSGRIRQNR 127
           E L    ++++  ++KI ++    + + VD+TLD +TA   L++SD+LR VR   ++Q+ 
Sbjct: 289 ESLKQFTEKMQSDMEKIQELR-EAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDL 347

Query: 128 QDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQLTTELGFW 187
            D  ERF++  C+LGSP F  GRH WEV+VG   +W +GVC +SV RKG +    + GFW
Sbjct: 348 PDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFW 407

Query: 188 TVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYTFRSVSAE 247
            VSL  G    A T P+T L +   LQRVGIFLD     VSF++     H +TF   +  
Sbjct: 408 AVSLWYGKEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFC 467

Query: 248 EPLRPFLAPSVPPNGDQGVLSICPL 272
            P+RP+ + S         L ICP+
Sbjct: 468 GPVRPYFSLSYSGGKSAAPLIICPM 492



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 1/77 (1%)

Query: 1  MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNK 60
          +A   Q+ ++CPVC  Y  +PM L+CG  +C  C+               C     +++ 
Sbjct: 6  VAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQRH- 64

Query: 61 IRRNRQLERLASHIKEL 77
          +R NR L  +   +K+L
Sbjct: 65 MRPNRHLANVTQLVKQL 81


>gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo
           sapiens]
          Length = 584

 Score =  149 bits (377), Expect = 2e-36
 Identities = 88/241 (36%), Positives = 128/241 (53%), Gaps = 27/241 (11%)

Query: 55  VSRKNKIRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQ------------------- 95
           ++   +  R R+++ +     E E  L++ LQ   + RK Q                   
Sbjct: 278 IALSRETEREREMKEMGYAATEQEISLREKLQEELKWRKIQYMARGEKSLAYHEWKMALF 337

Query: 96  --VDMTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCW 153
              D+ LD +TAN  LL+S+D RSV+     ++  D  ERF+   C+LG   FT GRH W
Sbjct: 338 KPADVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWRYCVLGCENFTSGRHYW 397

Query: 154 EVDVGTSTEWDLGVCRESVHR-KGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRK 212
           EV+VG   EW +GVC ++V R KG +++T E G+WT+ L DG +  A T P T L +   
Sbjct: 398 EVEVGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEP 457

Query: 213 LQRVGIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRP-FLAPSVPPNGDQGVLSICP 271
            ++VGIFLD     +SF++A  GSH+YTF   S  EPL P F   ++ P      L+ICP
Sbjct: 458 PRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPT----ALTICP 513

Query: 272 L 272
           +
Sbjct: 514 I 514


>gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo
           sapiens]
          Length = 542

 Score =  149 bits (377), Expect = 2e-36
 Identities = 88/241 (36%), Positives = 128/241 (53%), Gaps = 27/241 (11%)

Query: 55  VSRKNKIRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQ------------------- 95
           ++   +  R R+++ +     E E  L++ LQ   + RK Q                   
Sbjct: 236 IALSRETEREREMKEMGYAATEQEISLREKLQEELKWRKIQYMARGEKSLAYHEWKMALF 295

Query: 96  --VDMTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCW 153
              D+ LD +TAN  LL+S+D RSV+     ++  D  ERF+   C+LG   FT GRH W
Sbjct: 296 KPADVILDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWRYCVLGCENFTSGRHYW 355

Query: 154 EVDVGTSTEWDLGVCRESVHR-KGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRK 212
           EV+VG   EW +GVC ++V R KG +++T E G+WT+ L DG +  A T P T L +   
Sbjct: 356 EVEVGDRKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEP 415

Query: 213 LQRVGIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRP-FLAPSVPPNGDQGVLSICP 271
            ++VGIFLD     +SF++A  GSH+YTF   S  EPL P F   ++ P      L+ICP
Sbjct: 416 PRKVGIFLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVFRILTLEPT----ALTICP 471

Query: 272 L 272
           +
Sbjct: 472 I 472


>gi|153791360 ret finger protein-like 4B [Homo sapiens]
          Length = 263

 Score =  147 bits (370), Expect = 1e-35
 Identities = 98/273 (35%), Positives = 143/273 (52%), Gaps = 12/273 (4%)

Query: 1   MAALFQEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLC-CCSSMVSRKN 59
           MA   Q   SCPVC D+    +SL C    C  CI     E H    +C  C  +V  K 
Sbjct: 1   MAKRLQAELSCPVCLDFFSCSISLSCTHVFCFDCIQRYILENHDFRAMCPLCRDVV--KV 58

Query: 60  KIRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVR 119
                 Q+  L    K+   +L++ L +   +R F+ D+TLDA TA++ L+ S+DLRS +
Sbjct: 59  PALEEWQVSVLTLMTKQHNSRLEQSLHVREELRHFREDVTLDAATASSLLVFSNDLRSAQ 118

Query: 120 SGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQ 179
             +I     DL +   ++ C+LG+P F+ G+H WEV+VG    W LGVC+E   RK    
Sbjct: 119 CKKIHH---DLTKDPRLA-CVLGTPCFSSGQHYWEVEVGEVKSWSLGVCKEPADRKSN-D 173

Query: 180 LTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVY 239
           L  E GFW +S++  G + A T  L  +    +L+RVGIFLD  ++ + FFD ++   +Y
Sbjct: 174 LFPEHGFW-ISMK-AGAIHANT-HLERIPASPRLRRVGIFLDADLEEIQFFDVDNNVLIY 230

Query: 240 TFRSVSAEEPLRPFLAPSVPPNGDQG-VLSICP 271
           T     + E L PF    +   G+ G VL+ICP
Sbjct: 231 THDGFFSLELLCPFFCLELLGEGESGNVLTICP 263


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  145 bits (367), Expect = 3e-35
 Identities = 75/182 (41%), Positives = 107/182 (58%), Gaps = 1/182 (0%)

Query: 96  VDMTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEV 155
           V++ LDA TA   L+ SDDL+SVR G   +   D  +RFD  + +LGSP F  GR  WEV
Sbjct: 598 VNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEV 657

Query: 156 DVGTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQR 215
           +VG  T W LG C+ S+ RKG + L+ E G+W V +       A++VP T L +    +R
Sbjct: 658 EVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKR 717

Query: 216 VGIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRPFLAPSVPPNG-DQGVLSICPLMN 274
           VGIF+D  + ++SF++  + SH+YTF S S   PL+P  +P     G +   L+ICP+  
Sbjct: 718 VGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGG 777

Query: 275 SG 276
            G
Sbjct: 778 QG 779


>gi|222418658 butyrophilin, subfamily 3, member A1 isoform c [Homo
           sapiens]
          Length = 461

 Score =  145 bits (366), Expect = 4e-35
 Identities = 76/176 (43%), Positives = 107/176 (60%), Gaps = 5/176 (2%)

Query: 97  DMTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVD 156
           D+ LD  TAN  LL+S+D RSV+  +  Q+  D  ERF+   C+LG   F  GRH WEV+
Sbjct: 289 DVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVE 348

Query: 157 VGTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRV 216
           VG   EW +GVC ++V RKG +++T E GFWT+ L DG +    T P T L + +  ++V
Sbjct: 349 VGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKV 408

Query: 217 GIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRP-FLAPSVPPNGDQGVLSICP 271
           G+FLD    ++SF++A  GSH++TF  VS  E L P F   ++ P      L+ICP
Sbjct: 409 GVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPT----ALTICP 460


>gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo
           sapiens]
          Length = 513

 Score =  145 bits (366), Expect = 4e-35
 Identities = 76/176 (43%), Positives = 107/176 (60%), Gaps = 5/176 (2%)

Query: 97  DMTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVD 156
           D+ LD  TAN  LL+S+D RSV+  +  Q+  D  ERF+   C+LG   F  GRH WEV+
Sbjct: 341 DVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVE 400

Query: 157 VGTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRV 216
           VG   EW +GVC ++V RKG +++T E GFWT+ L DG +    T P T L + +  ++V
Sbjct: 401 VGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKV 460

Query: 217 GIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRP-FLAPSVPPNGDQGVLSICP 271
           G+FLD    ++SF++A  GSH++TF  VS  E L P F   ++ P      L+ICP
Sbjct: 461 GVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPT----ALTICP 512


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  141 bits (356), Expect = 6e-34
 Identities = 81/222 (36%), Positives = 122/222 (54%), Gaps = 2/222 (0%)

Query: 53  SMVSRKNKIRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLIS 112
           S+   +  + R+  L          E  L +I  M   +RKF  ++TLD  TAN +L++S
Sbjct: 243 SLEEVRGALERSEPLLLQCPEATTTELSLCRITGMKEMLRKFSTEITLDPATANAYLVLS 302

Query: 113 DDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESV 172
           +DL+SV+ G  RQ   D  ERFD S  +LG+  FT GRH WEV+VG  TEW++G+C++SV
Sbjct: 303 EDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSV 362

Query: 173 HRKGRIQLTTELGFWTVSLRDGGRLSA-TTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFD 231
            RKG +       F  + L+ G   S   + PL    V   + +VG+FLD    +++F++
Sbjct: 363 SRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYN 422

Query: 232 AESGSHVYTFRSVSAEEPLRPFLAPSVPPNG-DQGVLSICPL 272
               S +Y+F   S +E LRP  +P +P  G +   L+IC L
Sbjct: 423 GTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTICSL 464



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 6  QEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNKIRRNR 65
          +E  +C +C DY   P++ ECG + CL C+    +E H   L C            + N 
Sbjct: 11 REELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEE-HNTPLSCPECWRTLEGPHFQSNE 69

Query: 66 QLERLASHIKELEPKL 81
          +L RLAS  ++L  ++
Sbjct: 70 RLGRLASIARQLRSQV 85


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  140 bits (354), Expect = 1e-33
 Identities = 88/224 (39%), Positives = 129/224 (57%), Gaps = 11/224 (4%)

Query: 67  LERLAS-HIKELE---PKLKKILQ---MNPRMRKFQVDMTLDANTANNFLLISDDLRSVR 119
           LER  S ++K+L+   P+L+ +     +   +R   V +TLD +TAN +L++S+D R VR
Sbjct: 251 LERSESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVR 310

Query: 120 SGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQ 179
            G  +Q+     ERFD    +LG+  F  G+H WEVDV     WDLGVCR+SV RKG   
Sbjct: 311 LGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFL 370

Query: 180 LTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFD-AESGSHV 238
           L+++ GFWT+ L +  +  A T P T L +     +VGIFLD     VSF++  + GS +
Sbjct: 371 LSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLI 430

Query: 239 YTFRSVSAEEPLRPFLAPSVPPNG-DQGVLSICPLM--NSGTTD 279
           Y+F   +   PLRPF +P     G +   L++CPL   + G+TD
Sbjct: 431 YSFSECAFTGPLRPFFSPGFNDGGKNTAPLTLCPLNIGSQGSTD 474



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 3/77 (3%)

Query: 7  EASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNKIRRNRQ 66
          E  +CP+C D   +P+S+ECG + C +CI+ + K   G  +   C      KN +R NRQ
Sbjct: 12 EEVTCPICLDPFVEPVSIECGHSFCQECISQVGK--GGGSVCPVCRQRFLLKN-LRPNRQ 68

Query: 67 LERLASHIKELEPKLKK 83
          L  + +++KE+  + ++
Sbjct: 69 LANMVNNLKEISQEARE 85


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score =  134 bits (338), Expect = 7e-32
 Identities = 76/177 (42%), Positives = 105/177 (59%), Gaps = 4/177 (2%)

Query: 96  VDMTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEV 155
           VD+TLD +TA+  L + +D +SVR    RQ   +  ERFD   C+LG   FT GRH WEV
Sbjct: 303 VDVTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPCVLGRETFTSGRHYWEV 362

Query: 156 DVGTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQR 215
           +VG  T+W +GVCRE+V +KG   +T E GFW V L   G  + T +  T L +    +R
Sbjct: 363 EVGDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYGNGYWALTPL-RTPLPLAGPPRR 421

Query: 216 VGIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRPFLAPSVPPNGDQGVLSICPL 272
           VGIFLD    ++SF++   GS +YTF +V+   PLRPF       +  +  L+ICP+
Sbjct: 422 VGIFLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFCLW---SSGKKPLTICPI 475


>gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo
           sapiens]
          Length = 407

 Score =  134 bits (338), Expect = 7e-32
 Identities = 81/228 (35%), Positives = 117/228 (51%), Gaps = 8/228 (3%)

Query: 50  CCSSMVSRKNKIRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFL 109
           CC   + R+ KI    +  ++    KE+  +L++ L+   R      D+ LD +TA+  L
Sbjct: 168 CCIKKLQREKKILSGEK--KVEQEEKEIAQQLQEELRWR-RTFLHAADVVLDPDTAHPEL 224

Query: 110 LISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCR 169
            +S+D RSVR G  RQ   D  ERFD   C+LG   F  G+H WEV+V     W +GVCR
Sbjct: 225 FLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEVENVMVWTVGVCR 284

Query: 170 ESVHRKGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSF 229
            SV RKG + L  + GFWT+ +  G +  A + P   L +   L RVG+FLD    +VSF
Sbjct: 285 HSVERKGEVLLIPQNGFWTLEM-FGNQYRALSSPERILPLKESLCRVGVFLDYEAGDVSF 343

Query: 230 FDAESGSHVYTFRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGT 277
           ++    SH+YT    +   P+RPF         D   + ICP +   +
Sbjct: 344 YNMRDRSHIYTCPRSAFTVPVRPFFR----LGSDDSPIFICPALTGAS 387


>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
           sapiens]
          Length = 523

 Score =  134 bits (338), Expect = 7e-32
 Identities = 81/228 (35%), Positives = 117/228 (51%), Gaps = 8/228 (3%)

Query: 50  CCSSMVSRKNKIRRNRQLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFL 109
           CC   + R+ KI    +  ++    KE+  +L++ L+   R      D+ LD +TA+  L
Sbjct: 284 CCIKKLQREKKILSGEK--KVEQEEKEIAQQLQEELRWR-RTFLHAADVVLDPDTAHPEL 340

Query: 110 LISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCR 169
            +S+D RSVR G  RQ   D  ERFD   C+LG   F  G+H WEV+V     W +GVCR
Sbjct: 341 FLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEVENVMVWTVGVCR 400

Query: 170 ESVHRKGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSF 229
            SV RKG + L  + GFWT+ +  G +  A + P   L +   L RVG+FLD    +VSF
Sbjct: 401 HSVERKGEVLLIPQNGFWTLEM-FGNQYRALSSPERILPLKESLCRVGVFLDYEAGDVSF 459

Query: 230 FDAESGSHVYTFRSVSAEEPLRPFLAPSVPPNGDQGVLSICPLMNSGT 277
           ++    SH+YT    +   P+RPF         D   + ICP +   +
Sbjct: 460 YNMRDRSHIYTCPRSAFTVPVRPFFR----LGSDDSPIFICPALTGAS 503


>gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precursor
           [Homo sapiens]
          Length = 527

 Score =  134 bits (337), Expect = 9e-32
 Identities = 90/251 (35%), Positives = 130/251 (51%), Gaps = 16/251 (6%)

Query: 29  AVCLKCINSLQKEPHGEDLLCCCSSMVSRKNKIRRNRQLERLASHIKELEPKLKKILQMN 88
           AVC+  IN LQKE      +        R+ +    ++LE+     KE E ++K+ LQ  
Sbjct: 263 AVCIYWINKLQKEKK----ILSGEKEFERETREIALKELEKERVQ-KEEELQVKEKLQEE 317

Query: 89  PRMRK---FQVDMTLDANTANNFLLISDDLRSVRSGRIR---QNRQDLAERFDVSVCILG 142
            R R+     VD+ LD +TA+  L +S+D RSVR    R   ++  D  ERFD   C+LG
Sbjct: 318 LRWRRTFLHAVDVVLDPDTAHPDLFLSEDRRSVRRCPFRHLGESVPDNPERFDSQPCVLG 377

Query: 143 SPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATTV 202
              F  G+H WEV+V    EW +GVCR+SV RKG + L  + GFWT+ +   G+  A + 
Sbjct: 378 RESFASGKHYWEVEVENVIEWTVGVCRDSVERKGEVLLIPQNGFWTLEMHK-GQYRAVSS 436

Query: 203 PLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRPFLAPSVPPNG 262
           P   L +   L RVG+FLD    +VSF++    SH+YT    +   P+RPF         
Sbjct: 437 PDRILPLKESLCRVGVFLDYEAGDVSFYNMRDRSHIYTCPRSAFSVPVRPFFRLGC---- 492

Query: 263 DQGVLSICPLM 273
           +   + ICP +
Sbjct: 493 EDSPIFICPAL 503


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  132 bits (333), Expect = 3e-31
 Identities = 80/192 (41%), Positives = 112/192 (58%), Gaps = 7/192 (3%)

Query: 91  MRKFQVDMTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGR 150
           +R+F+ D+TLD +TAN  L++S+D RSV+ G +RQ   D  ERFD   C+LG  RFT GR
Sbjct: 282 LRRFRGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGR 341

Query: 151 HCWEVDVGTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVD 210
           H WEV+VG  T W LGVCRE+V+RK + +L+   GFW +    G   +++   L  L   
Sbjct: 342 HYWEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFL-GSYYNSSERALAPL--R 398

Query: 211 RKLQRVGIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRPFLAPSVPPNGDQGVLSIC 270
              +RVGIFLD    ++SF+ A  GS ++ F  +     LRP  +P    +     ++IC
Sbjct: 399 DPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPL---SSSPTPMTIC 455

Query: 271 -PLMNSGTTDAP 281
            P   SG T AP
Sbjct: 456 RPKGGSGDTLAP 467



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 1/74 (1%)

Query: 6  QEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNKIRRNR 65
          QE ++C +C DY   P+  +CG   C +CI     +P G      C  +  ++N +R NR
Sbjct: 11 QEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRN-LRPNR 69

Query: 66 QLERLASHIKELEP 79
           L ++A   + L P
Sbjct: 70 PLAKMAEMARRLHP 83


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  131 bits (330), Expect = 6e-31
 Identities = 76/194 (39%), Positives = 109/194 (56%), Gaps = 8/194 (4%)

Query: 66  QLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRSGRIR- 124
           +LE+  S+       L+KIL      ++   D+TLD  TA+  L++S+D +SV+    R 
Sbjct: 283 ELEKNFSNFPRQYFALRKIL------KQLIADVTLDPETAHPNLVLSEDRKSVKFVETRL 336

Query: 125 QNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQLTTEL 184
           ++  D   RF    C+L +  FT GRH WEV+VG  T W +GVCR+SV RKG +    E 
Sbjct: 337 RDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPET 396

Query: 185 GFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYTFRSV 244
           G+W V L +G + +ATT P T L +  K +RVGIFLD     +SF++    SH+YTF   
Sbjct: 397 GYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDT 456

Query: 245 SAEEPLRPFLAPSV 258
             E+ L P   P +
Sbjct: 457 FTEK-LWPLFYPGI 469



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 6   QEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNKIRRNR 65
           Q  +SC VC +YL++P+ +ECG   C  CI    ++    D  C      SR   +R NR
Sbjct: 24  QVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLE-RDFPCPVCRKTSRYRSLRPNR 82

Query: 66  QLERLASHIKELEPKLKKI 84
           QL  +    K+L+   +KI
Sbjct: 83  QLGSMVEIAKQLQAVKRKI 101


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  131 bits (330), Expect = 6e-31
 Identities = 76/194 (39%), Positives = 109/194 (56%), Gaps = 8/194 (4%)

Query: 66  QLERLASHIKELEPKLKKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRSGRIR- 124
           +LE+  S+       L+KIL      ++   D+TLD  TA+  L++S+D +SV+    R 
Sbjct: 313 ELEKNFSNFPRQYFALRKIL------KQLIADVTLDPETAHPNLVLSEDRKSVKFVETRL 366

Query: 125 QNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQLTTEL 184
           ++  D   RF    C+L +  FT GRH WEV+VG  T W +GVCR+SV RKG +    E 
Sbjct: 367 RDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPET 426

Query: 185 GFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYTFRSV 244
           G+W V L +G + +ATT P T L +  K +RVGIFLD     +SF++    SH+YTF   
Sbjct: 427 GYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDT 486

Query: 245 SAEEPLRPFLAPSV 258
             E+ L P   P +
Sbjct: 487 FTEK-LWPLFYPGI 499



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 6   QEASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNKIRRNR 65
           Q  +SC VC +YL++P+ +ECG   C  CI    ++    D  C      SR   +R NR
Sbjct: 24  QVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLE-RDFPCPVCRKTSRYRSLRPNR 82

Query: 66  QLERLASHIKELEPKLKKI 84
           QL  +    K+L+   +KI
Sbjct: 83  QLGSMVEIAKQLQAVKRKI 101


>gi|63054855 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  126 bits (317), Expect = 2e-29
 Identities = 84/221 (38%), Positives = 116/221 (52%), Gaps = 6/221 (2%)

Query: 69  RLASHIKELEPKLK-KILQMNPRMRKFQ---VDMTLDANTANNFLLISDDLRSVRSGRIR 124
           +L   +K+L  +LK K    N   R+ +   V +TLD +TA+  L++S+D R VR G  R
Sbjct: 207 KLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDPDTAHPKLILSEDQRCVRLGDRR 266

Query: 125 QNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQLTTEL 184
           Q   D  +RFD  V ILGS  FT G H WEV VG  T+W LGVC ESV RKG++  +   
Sbjct: 267 QPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPAN 326

Query: 185 GFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYTFRSV 244
           G W +    G    A T P T   +    + VGIFLD     +SF++  + SH++TF + 
Sbjct: 327 GHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTF-TH 385

Query: 245 SAEEPLRPFLAPSVPPNG-DQGVLSICPLMNSGTTDAPVRP 284
           +   PLRPF  P +   G +   L IC  ++        RP
Sbjct: 386 NFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIVPRP 426


>gi|19923536 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  126 bits (317), Expect = 2e-29
 Identities = 84/221 (38%), Positives = 116/221 (52%), Gaps = 6/221 (2%)

Query: 69  RLASHIKELEPKLK-KILQMNPRMRKFQ---VDMTLDANTANNFLLISDDLRSVRSGRIR 124
           +L   +K+L  +LK K    N   R+ +   V +TLD +TA+  L++S+D R VR G  R
Sbjct: 207 KLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDPDTAHPKLILSEDQRCVRLGDRR 266

Query: 125 QNRQDLAERFDVSVCILGSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQLTTEL 184
           Q   D  +RFD  V ILGS  FT G H WEV VG  T+W LGVC ESV RKG++  +   
Sbjct: 267 QPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPAN 326

Query: 185 GFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYTFRSV 244
           G W +    G    A T P T   +    + VGIFLD     +SF++  + SH++TF + 
Sbjct: 327 GHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTF-TH 385

Query: 245 SAEEPLRPFLAPSVPPNG-DQGVLSICPLMNSGTTDAPVRP 284
           +   PLRPF  P +   G +   L IC  ++        RP
Sbjct: 386 NFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIVPRP 426


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  125 bits (315), Expect = 3e-29
 Identities = 71/188 (37%), Positives = 101/188 (53%), Gaps = 6/188 (3%)

Query: 82  KKILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCIL 141
           K    +   +R  QV +TLD +TA++ L++S+D R V  G  ++N+   + RF    C+L
Sbjct: 278 KLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVL 337

Query: 142 GSPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATT 201
           G   FT GR  +EVDVG  T WDLGVC E+V R   ++   + GFWT+ L       A T
Sbjct: 338 GCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALT 397

Query: 202 VPLTFLFVDRKLQRVGIFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRPFLAP----- 256
            P T L +  +   VGIFLD     VSF++  +G H++TF   S  + LRP+        
Sbjct: 398 SPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSP 457

Query: 257 -SVPPNGD 263
             +PP GD
Sbjct: 458 LFLPPPGD 465



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 5/80 (6%)

Query: 7  EASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDL----LCCCSSMVS-RKNKI 61
          E ++C +C   +  P+S+ CG + C  CI    K P  + L     CC         + +
Sbjct: 12 EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMDSL 71

Query: 62 RRNRQLERLASHIKELEPKL 81
          R N+QL  L   +KE + ++
Sbjct: 72 RPNKQLGSLIEALKETDQEM 91


>gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]
          Length = 341

 Score =  122 bits (307), Expect = 3e-28
 Identities = 68/166 (40%), Positives = 98/166 (59%), Gaps = 1/166 (0%)

Query: 98  MTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDV 157
           +TLD  TA+  L++S    SV  G I++   D  ERFD SV +LGS  FT G+  WEV+V
Sbjct: 166 LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEV 225

Query: 158 GTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVG 217
              T+W +GV RES+ RKG   LT E GFW + LR+   L A  +P   L +   L +VG
Sbjct: 226 AKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVG 285

Query: 218 IFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRPFLAPSVPPNGD 263
           I+LD     +SF++A++ +H+YTF +   E+ L P+  P +   G+
Sbjct: 286 IYLDYEGGQLSFYNAKTMTHIYTFSNTFMEK-LYPYFCPCLNDGGE 330


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  122 bits (307), Expect = 3e-28
 Identities = 68/166 (40%), Positives = 98/166 (59%), Gaps = 1/166 (0%)

Query: 98  MTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILGSPRFTCGRHCWEVDV 157
           +TLD  TA+  L++S    SV  G I++   D  ERFD SV +LGS  FT G+  WEV+V
Sbjct: 325 LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEV 384

Query: 158 GTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATTVPLTFLFVDRKLQRVG 217
              T+W +GV RES+ RKG   LT E GFW + LR+   L A  +P   L +   L +VG
Sbjct: 385 AKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVG 444

Query: 218 IFLDMGMQNVSFFDAESGSHVYTFRSVSAEEPLRPFLAPSVPPNGD 263
           I+LD     +SF++A++ +H+YTF +   E+ L P+  P +   G+
Sbjct: 445 IYLDYEGGQLSFYNAKTMTHIYTFSNTFMEK-LYPYFCPCLNDGGE 489



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 14/116 (12%)

Query: 11  CPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGEDLLCCCSSMVSRKNKIRRNRQLERL 70
           CP+C+D+   P+ L CG   C  CI    +    ++  C    M+ + N    N  L++L
Sbjct: 41  CPLCNDWFRDPLMLSCGHNFCEACIQDFWR-LQAKETFCPECKMLCQYNNCTFNPVLDKL 99

Query: 71  ASHIKELE------------PKLKKILQMNPRMRKFQV-DMTLDANTANNFLLISD 113
              IK+L               LK   + + ++  FQ  D  L    +  FL ISD
Sbjct: 100 VEKIKKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFLQISD 155


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  119 bits (297), Expect = 4e-27
 Identities = 68/193 (35%), Positives = 106/193 (54%), Gaps = 4/193 (2%)

Query: 83  KILQMNPRMRKFQVDMTLDANTANNFLLISDDLRSVRSGRIRQNRQDLAERFDVSVCILG 142
           ++L +   ++ +  D+ LD +TA + L++S+D + V  G   Q   D  ERF     +LG
Sbjct: 290 RVLGLREILKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLG 349

Query: 143 SPRFTCGRHCWEVDVGTSTEWDLGVCRESVHRKGRIQLTTELGFWTVSLRDGGRLSATTV 202
           S   + GRH WEV+VG  +EW LGVC+++V RK  + L+   GFW + LR G    A T 
Sbjct: 350 SQCISSGRHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTD 409

Query: 203 PLTFLFVDRKLQRVGIFLDMGMQNVSFFD-AESGSHVYTFRSVSAEEPLRPFLAP--SVP 259
               L +    +RVGIF+D    ++SF++  + GSH++TF        L P+ +P  S+ 
Sbjct: 410 EYPILSLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYSIG 469

Query: 260 PNGDQGVLSICPL 272
            N +   L+IC L
Sbjct: 470 TN-NTAPLAICSL 481



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 7/76 (9%)

Query: 7  EASSCPVCSDYLEKPMSLECGCAVCLKCINSLQKEPHGED----LLC-CCSSMVSRKNKI 61
          E  +CP+C  +L +PMS++CG + C  C++ L + P GE       C  C + V  +N +
Sbjct: 12 EEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIP-GESQNWGYTCPLCRAPVQPRN-L 69

Query: 62 RRNRQLERLASHIKEL 77
          R N QL  +   ++ L
Sbjct: 70 RPNWQLANVVEKVRLL 85


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,040,056
Number of Sequences: 37866
Number of extensions: 479163
Number of successful extensions: 1833
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 179
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1405
Number of HSP's gapped (non-prelim): 296
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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