Search of human proteins with 226437621

Search of human proteins with 226437621

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226437621 PRAME family member 11 [Homo sapiens]
         (436 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226437621 PRAME family member 11 [Homo sapiens]                    897   0.0  
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]         897   0.0  
gi|148356236 PRAME family member 15 [Homo sapiens]                    867   0.0  
gi|61102721 PRAME family member 9 [Homo sapiens]                      867   0.0  
gi|59958373 PRAME family member 4 [Homo sapiens]                      862   0.0  
gi|61696142 PRAME family member 5 [Homo sapiens]                      853   0.0  
gi|58219004 PRAME family member 6 [Homo sapiens]                      852   0.0  
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]         848   0.0  
gi|88942379 PREDICTED: PRAME family member [Homo sapiens]             748   0.0  
gi|153792112 PRAME family member 20 [Homo sapiens]                    699   0.0  
gi|153945800 PRAME family member 21 [Homo sapiens]                    699   0.0  
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]    606   e-173
gi|239741053 PREDICTED: similar to Putative PRAME family member ...   507   e-144
gi|59676593 PRAME family member 7 [Homo sapiens]                      506   e-143
gi|59676587 PRAME family member 8 [Homo sapiens]                      505   e-143
gi|124249372 PRAME family member 12 [Homo sapiens]                    498   e-141
gi|46249373 preferentially expressed antigen in melanoma [Homo s...   386   e-107
gi|46249371 preferentially expressed antigen in melanoma [Homo s...   386   e-107
gi|46249369 preferentially expressed antigen in melanoma [Homo s...   386   e-107
gi|46249367 preferentially expressed antigen in melanoma [Homo s...   386   e-107
gi|5174641 preferentially expressed antigen in melanoma [Homo sa...   386   e-107
gi|113865933 PRAME family member 16 [Homo sapiens]                    363   e-100
gi|154800493 PRAME family member 22 [Homo sapiens]                    362   e-100
gi|157426839 PRAME family member 17 [Homo sapiens]                    360   1e-99
gi|153791443 PRAME family member 18 [Homo sapiens]                    358   7e-99
gi|194306638 PRAME family member 3 [Homo sapiens]                     356   3e-98
gi|194018546 PRAME family member 10 [Homo sapiens]                    355   4e-98
gi|194306635 PRAME family member 19 [Homo sapiens]                    354   8e-98
gi|66954681 PRAME family member 13 [Homo sapiens]                     350   2e-96
gi|12738831 PRAME family member 1 [Homo sapiens]                      348   4e-96

>gi|226437621 PRAME family member 11 [Homo sapiens]
          Length = 436

 Score =  897 bits (2319), Expect = 0.0
 Identities = 436/436 (100%), Positives = 436/436 (100%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL
Sbjct: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL
Sbjct: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS
Sbjct: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD
Sbjct: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420

Query: 421 HGDRSFYDLEADQYCC 436
           HGDRSFYDLEADQYCC
Sbjct: 421 HGDRSFYDLEADQYCC 436


>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
          Length = 513

 Score =  897 bits (2319), Expect = 0.0
 Identities = 436/436 (100%), Positives = 436/436 (100%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL
Sbjct: 78  MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 137

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL
Sbjct: 138 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 197

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI
Sbjct: 198 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 257

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 258 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 317

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 318 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 377

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS
Sbjct: 378 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 437

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD
Sbjct: 438 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 497

Query: 421 HGDRSFYDLEADQYCC 436
           HGDRSFYDLEADQYCC
Sbjct: 498 HGDRSFYDLEADQYCC 513


>gi|148356236 PRAME family member 15 [Homo sapiens]
          Length = 478

 Score =  867 bits (2241), Expect = 0.0
 Identities = 422/436 (96%), Positives = 429/436 (98%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL
Sbjct: 43  MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 102

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNK PVQDCPRMR RQPLTVFVELWLKNRTL
Sbjct: 103 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTL 162

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEYLT LLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPI
Sbjct: 163 DEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPI 222

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           LTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 223 LTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 282

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 283 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 342

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS
Sbjct: 343 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 402

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTIILKNLC+ELYPAP+ESYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD
Sbjct: 403 HTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPD 462

Query: 421 HGDRSFYDLEADQYCC 436
            G+RSFYDLEADQYCC
Sbjct: 463 CGNRSFYDLEADQYCC 478


>gi|61102721 PRAME family member 9 [Homo sapiens]
          Length = 478

 Score =  867 bits (2241), Expect = 0.0
 Identities = 422/436 (96%), Positives = 429/436 (98%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL
Sbjct: 43  MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 102

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNK PVQDCPRMR RQPLTVFVELWLKNRTL
Sbjct: 103 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTL 162

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEYLT LLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPI
Sbjct: 163 DEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPI 222

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           LTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 223 LTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 282

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 283 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 342

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS
Sbjct: 343 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 402

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTIILKNLC+ELYPAP+ESYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD
Sbjct: 403 HTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPD 462

Query: 421 HGDRSFYDLEADQYCC 436
            G+RSFYDLEADQYCC
Sbjct: 463 CGNRSFYDLEADQYCC 478


>gi|59958373 PRAME family member 4 [Homo sapiens]
          Length = 478

 Score =  862 bits (2228), Expect = 0.0
 Identities = 417/436 (95%), Positives = 427/436 (97%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCEALKLMVQ+WPFRRLPLRPLIKMPCLEAFQAVLDGLDALL  GVRPRRWKL
Sbjct: 43  MEAFSRRRCEALKLMVQSWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKL 102

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNK PV+DCPRMR RQPLTVFVELWLKNRTL
Sbjct: 103 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTL 162

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEYLTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPI
Sbjct: 163 DEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPI 222

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           LTQFTPYLGH+RNLQKL+LSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 223 LTQFTPYLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 282

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLLSCLKTSLK LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 283 LEGHLDQLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 342

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS
Sbjct: 343 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 402

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTIILKNLC+ELYPAP+ESYGADGTLCWSRFAQIRAELM +VR LRHPKRILFCTD CPD
Sbjct: 403 HTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPD 462

Query: 421 HGDRSFYDLEADQYCC 436
            G+RSFYDLEADQYCC
Sbjct: 463 CGNRSFYDLEADQYCC 478


>gi|61696142 PRAME family member 5 [Homo sapiens]
          Length = 476

 Score =  853 bits (2204), Expect = 0.0
 Identities = 417/436 (95%), Positives = 425/436 (97%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKL
Sbjct: 41  MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNK PVQDCPRMR +QPLTVFVELWLKNRTL
Sbjct: 101 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTL 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEYLTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPI
Sbjct: 161 DEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPI 220

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           LTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSF
Sbjct: 221 LTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSF 280

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 281 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 340

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLS
Sbjct: 341 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLS 400

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTIILKNLC+ELYPAP+ESY ADGTLCWSRFAQIRAELMK+VR LRHPKRILFCTD CPD
Sbjct: 401 HTIILKNLCVELYPAPRESYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPD 460

Query: 421 HGDRSFYDLEADQYCC 436
            G+RSFYDLEADQ CC
Sbjct: 461 CGNRSFYDLEADQCCC 476


>gi|58219004 PRAME family member 6 [Homo sapiens]
          Length = 476

 Score =  852 bits (2202), Expect = 0.0
 Identities = 417/436 (95%), Positives = 425/436 (97%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKL
Sbjct: 41  MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDVCENFWMVWSEAMA GCFLNAKRNKTPVQDCPRMR +QPLTVFVELWLKNRTL
Sbjct: 101 QVLDLQDVCENFWMVWSEAMARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTL 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEYLTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPI
Sbjct: 161 DEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPI 220

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           LTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSF
Sbjct: 221 LTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSF 280

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 281 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 340

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLLS
Sbjct: 341 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLS 400

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTIILKNLC+ELYPAP+ESY ADGTLCWSRFAQIRAELMK+VR LRHPKRILFCTD CPD
Sbjct: 401 HTIILKNLCVELYPAPRESYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPD 460

Query: 421 HGDRSFYDLEADQYCC 436
            G+RSFYDLEADQ CC
Sbjct: 461 CGNRSFYDLEADQCCC 476


>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
          Length = 476

 Score =  848 bits (2191), Expect = 0.0
 Identities = 415/436 (95%), Positives = 423/436 (97%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGV PRRWKL
Sbjct: 41  MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNK PVQDCPRMR +QPLTVFVELWLKNRTL
Sbjct: 101 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTL 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEYLTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW+LPI
Sbjct: 161 DEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPI 220

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           LTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL MNSVSF
Sbjct: 221 LTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSF 280

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP
Sbjct: 281 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 340

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALS CFELNTFSFCGNPI MATLENLLS
Sbjct: 341 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLS 400

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTIILKNLC+ELYPAP+ESY ADGTLCWSRF QIRAELMK+VR LRHPKRILFCTD CPD
Sbjct: 401 HTIILKNLCVELYPAPRESYDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPD 460

Query: 421 HGDRSFYDLEADQYCC 436
            G+RSFYDLEADQ CC
Sbjct: 461 CGNRSFYDLEADQCCC 476


>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
          Length = 395

 Score =  748 bits (1931), Expect = 0.0
 Identities = 364/381 (95%), Positives = 371/381 (97%)

Query: 56  RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWL 115
           RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNK PVQDCPRMR RQPLTVFVELWL
Sbjct: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74

Query: 116 KNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 175
           KNRTLDE+LTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134

Query: 176 WILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 235
           W+LPILTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKLYM
Sbjct: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194

Query: 236 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 295
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254

Query: 296 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 355
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATL
Sbjct: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314

Query: 356 ENLLSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCT 415
           ENLLSHTIILKNLCLELYPAP+ESYGADGTLCWSRF QIRAELMK+VR LRHPKRILF T
Sbjct: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374

Query: 416 DNCPDHGDRSFYDLEADQYCC 436
           D CPD G+RSFYDLEADQYCC
Sbjct: 375 DYCPDCGNRSFYDLEADQYCC 395


>gi|153792112 PRAME family member 20 [Homo sapiens]
          Length = 475

 Score =  699 bits (1805), Expect = 0.0
 Identities = 347/436 (79%), Positives = 374/436 (85%), Gaps = 1/436 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRR CEALKLMVQAWPF RLPL  L+K PC E FQAVLDGLDALLT  VR RRWKL
Sbjct: 41  MEAFSRRHCEALKLMVQAWPFLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDV ENFWMVWSEAMA  C  NA  N+ PVQDCPRMR +QPLTVF++L LKNRTL
Sbjct: 101 QVLDLQDVSENFWMVWSEAMARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTL 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEY TCL LWVKQR  L+HLCCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+
Sbjct: 161 DEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPV 220

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           L +FTPYLG +RNL+KLVLS +D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 221 LAEFTPYLGQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSF 279

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQ+LSCLKTSL +L ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVP
Sbjct: 280 LEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVP 339

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQ+LLEKVAATLEYLDLDDCGI+DSQVNAILPALSRCFEL TFSF GNPI  ATLENLL 
Sbjct: 340 LQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLC 399

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTI L NLCLELYPAP+ESY   G +C SRFAQ+ AELM +VR LR P+RILFCTD CP 
Sbjct: 400 HTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQ 459

Query: 421 HGDRSFYDLEADQYCC 436
            G+RS YDLE D+ CC
Sbjct: 460 CGNRSLYDLEVDRCCC 475


>gi|153945800 PRAME family member 21 [Homo sapiens]
          Length = 475

 Score =  699 bits (1805), Expect = 0.0
 Identities = 347/436 (79%), Positives = 374/436 (85%), Gaps = 1/436 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRR CEALKLMVQAWPF RLPL  L+K PC E FQAVLDGLDALLT  VR RRWKL
Sbjct: 41  MEAFSRRHCEALKLMVQAWPFLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDLQDV ENFWMVWSEAMA  C  NA  N+ PVQDCPRMR +QPLTVF++L LKNRTL
Sbjct: 101 QVLDLQDVSENFWMVWSEAMARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTL 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DEY TCL LWVKQR  L+HLCCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+
Sbjct: 161 DEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPV 220

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           L +FTPYLG +RNL+KLVLS +D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 221 LAEFTPYLGQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSF 279

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQ+LSCLKTSL +L ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVP
Sbjct: 280 LEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVP 339

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           LQ+LLEKVAATLEYLDLDDCGI+DSQVNAILPALSRCFEL TFSF GNPI  ATLENLL 
Sbjct: 340 LQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLC 399

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HTI L NLCLELYPAP+ESY   G +C SRFAQ+ AELM +VR LR P+RILFCTD CP 
Sbjct: 400 HTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQ 459

Query: 421 HGDRSFYDLEADQYCC 436
            G+RS YDLE D+ CC
Sbjct: 460 CGNRSLYDLEVDRCCC 475


>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
          Length = 474

 Score =  606 bits (1562), Expect = e-173
 Identities = 312/437 (71%), Positives = 349/437 (79%), Gaps = 4/437 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           +EAF+ RRCE LK+MVQAWPF  LPL  L+K P LE    V+DG+D LL Q VRPRR KL
Sbjct: 41  VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVL+L+DV ENFW +WS A    C   A   +  V+DCPR  E+QPL VF+++ LK + +
Sbjct: 101 QVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFM 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
           DE L+    WV+ RR  +HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   
Sbjct: 161 DEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCM 220

Query: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVS 239
           I+ +F+PYL  +RNL+KL +S  D  RY+     +E +  FTTQFLKL CLQKLYMNSVS
Sbjct: 221 IV-EFSPYLSQMRNLRKLFIS--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVS 277

Query: 240 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 299
           FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV
Sbjct: 278 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 337

Query: 300 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLL 359
           PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATLENLL
Sbjct: 338 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLL 397

Query: 360 SHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 419
           SHTIILKNLCLELYPAP+ESYGADGTLCWSRF QIRAELMK+VR LRHPKRILF TD CP
Sbjct: 398 SHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCP 457

Query: 420 DHGDRSFYDLEADQYCC 436
           D G+RSFYDLEADQYCC
Sbjct: 458 DCGNRSFYDLEADQYCC 474


>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
           [Homo sapiens]
          Length = 474

 Score =  507 bits (1305), Expect = e-144
 Identities = 261/436 (59%), Positives = 319/436 (73%), Gaps = 2/436 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCE LK MVQAWPF RLPL  L+K P LE+ ++VL+G+D LLTQ VRPR+ KL
Sbjct: 41  MEAFSRRRCETLKTMVQAWPFTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDL++V ENF  ++S A A   F  A   K    +CP    +QP  VF++L LKNRTL
Sbjct: 101 QVLDLRNVDENFCDIFSGATAS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTL 158

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DE LT LL W KQR+ LLH+CCK+L++ GMP  +I  +L MV LDCIQEVEV C W L  
Sbjct: 159 DECLTHLLEWGKQRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELST 218

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           L +F PYLG +RNL+KLVL ++  S  + P+ K + + +FT+QFLKL   Q L M+SVSF
Sbjct: 219 LVKFAPYLGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSF 278

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLL CL+ SL+++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S  P
Sbjct: 279 LEGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEP 338

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           L  LLE+V ATL+ LDL+DCGI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL 
Sbjct: 339 LTGLLEQVVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLR 398

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HT+ L  L LELYPAP ESY   G LCW RFA++ AELMK +R LR PK I+FCT  CP 
Sbjct: 399 HTVGLSKLSLELYPAPLESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPR 458

Query: 421 HGDRSFYDLEADQYCC 436
            G R+ YDLE     C
Sbjct: 459 CGIRASYDLEPSHCLC 474


>gi|59676593 PRAME family member 7 [Homo sapiens]
          Length = 474

 Score =  506 bits (1302), Expect = e-143
 Identities = 261/436 (59%), Positives = 318/436 (72%), Gaps = 2/436 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCE LK MVQAWPF RLPL  L+K P LE+ ++VL+G+D LLTQ VRPR+ KL
Sbjct: 41  MEAFSRRRCETLKTMVQAWPFTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDL++V ENF  ++S A A   F  A   K    +CP    +QP  VF++L LKNRTL
Sbjct: 101 QVLDLRNVDENFCDIFSGATAS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTL 158

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DE LT LL W KQR+ LLH+CCK+L++ GMP  +I  +L MV LDCIQEVEV C W L  
Sbjct: 159 DECLTHLLEWGKQRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELST 218

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           L +F PYLG +RNL+KLVL ++  S  + P+ K + + +FT+QFLKL   Q L M+SVSF
Sbjct: 219 LVKFAPYLGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSF 278

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLL CL+ SL+++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S  P
Sbjct: 279 LEGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEP 338

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           L  LLE+V ATL+ LDL+DCGI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL 
Sbjct: 339 LTGLLEQVVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLR 398

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HT+ L  L LELYPAP ESY   G LCW RFA++ AELMK  R LR PK I+FCT  CP 
Sbjct: 399 HTVGLSKLSLELYPAPLESYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPR 458

Query: 421 HGDRSFYDLEADQYCC 436
            G R+ YDLE     C
Sbjct: 459 CGIRASYDLEPSHCLC 474


>gi|59676587 PRAME family member 8 [Homo sapiens]
          Length = 474

 Score =  505 bits (1301), Expect = e-143
 Identities = 260/436 (59%), Positives = 319/436 (73%), Gaps = 2/436 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRRRCE LK MVQAWPF RLPL  L+K P LE+ ++VL+G+D LLTQ VRPR+ KL
Sbjct: 41  MEAFSRRRCETLKTMVQAWPFTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDL++V ENF  ++S A A   F  A   K    +CP    +QP  VF++L LKNRTL
Sbjct: 101 QVLDLRNVDENFCDIFSGATAS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTL 158

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DE LT LL W KQR+ LLH+CC++L++ GMP  +I  +L MV LDCIQEVEV C W L  
Sbjct: 159 DECLTHLLEWGKQRKGLLHVCCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELST 218

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           L +F PYLG +RNL+KLVL ++  S  + P+ K + + +FT+QFLKL   Q L M+SVSF
Sbjct: 219 LVKFAPYLGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSF 278

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLL CL+ SL+++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT++S  P
Sbjct: 279 LEGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEP 338

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           L  LLE+V ATL+ LDL+DCGI+DSQ++AILP LSRC +L+TFSFCGN I MA LENLL 
Sbjct: 339 LTGLLEQVVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLR 398

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HT+ L  L LELYPAP ESY   G LCW RFA++ AELMK +R LR PK I+FCT  CP 
Sbjct: 399 HTVGLSKLSLELYPAPLESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPR 458

Query: 421 HGDRSFYDLEADQYCC 436
            G R+ YDLE     C
Sbjct: 459 CGIRASYDLEPSHCLC 474


>gi|124249372 PRAME family member 12 [Homo sapiens]
          Length = 483

 Score =  498 bits (1283), Expect = e-141
 Identities = 261/430 (60%), Positives = 313/430 (72%), Gaps = 2/430 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAF+RR CE L  MVQAWPF  LPL  L+K   LE F+AVL+GLDALL Q VRPRRWKL
Sbjct: 41  MEAFTRRCCETLTTMVQAWPFTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDL++V ENFW +WS A A      +KR      +CPR   +QPL V ++L  KN  L
Sbjct: 101 QVLDLRNVDENFWGIWSGASALSPEALSKRRTAG--NCPRPGGQQPLMVILDLCFKNGML 158

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DE LT  L W KQR+ LLH+CCK+L+I G+    I  +L  V LDCIQEVEV C W L I
Sbjct: 159 DECLTHFLEWGKQRKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSI 218

Query: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
           L +F PYLG +RNL+KLVL ++ VS  +  ++K++ V QFT+QFLKL   QKLYM+SVSF
Sbjct: 219 LIRFAPYLGQMRNLRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSF 278

Query: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
           LEGHLDQLL CL+  L+ + +T C+L ESDLKHLS CPSI QLK LDL GI LT++S  P
Sbjct: 279 LEGHLDQLLRCLQAPLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEP 338

Query: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
           L +LLE+  ATL+ LDL+DCGI+DSQ++AILPALSRC +L+TFSFCGN I MA LENLL 
Sbjct: 339 LSVLLEQAEATLQTLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLR 398

Query: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
           HT+ L  L LELYPAP ESY A G LCW RF+Q+ AELMK +R LR PK I+F T  CP 
Sbjct: 399 HTVGLSKLSLELYPAPLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPR 458

Query: 421 HGDRSFYDLE 430
            G R+ YDLE
Sbjct: 459 CGIRASYDLE 468


>gi|46249373 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  386 bits (992), Expect = e-107
 Identities = 214/442 (48%), Positives = 282/442 (63%), Gaps = 12/442 (2%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRW 58
           M AF  R  + LK MVQAWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRW
Sbjct: 58  MAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRW 117

Query: 59  KLQVLDLQ-DVCENFWMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTV 109
           KLQVLDL+ +  ++FW VWS   A               K+ K         +   P+ V
Sbjct: 118 KLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEV 177

Query: 110 FVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQE 169
            V+L+LK    DE  + L+  VK+++++L LCCKKLKI  MP ++I+ ILKMV LD I++
Sbjct: 178 LVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIED 237

Query: 170 VEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRC 229
           +EV C W LP L +F+PYLG + NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+C
Sbjct: 238 LEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQC 297

Query: 230 LQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLS 289
           LQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LS
Sbjct: 298 LQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLS 357

Query: 290 GIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNP 349
           G+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN 
Sbjct: 358 GVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNS 417

Query: 350 ICMATLENLLSHTIILKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHP 408
           I ++ L++LL H I L NL   LYP P ESY    GTL   R A + A L + +  L  P
Sbjct: 418 ISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRP 477

Query: 409 KRILFCTDNCPDHGDRSFYDLE 430
             +    + CP  GDR+FYD E
Sbjct: 478 SMVWLSANPCPHCGDRTFYDPE 499


>gi|46249371 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  386 bits (992), Expect = e-107
 Identities = 214/442 (48%), Positives = 282/442 (63%), Gaps = 12/442 (2%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRW 58
           M AF  R  + LK MVQAWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRW
Sbjct: 58  MAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRW 117

Query: 59  KLQVLDLQ-DVCENFWMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTV 109
           KLQVLDL+ +  ++FW VWS   A               K+ K         +   P+ V
Sbjct: 118 KLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEV 177

Query: 110 FVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQE 169
            V+L+LK    DE  + L+  VK+++++L LCCKKLKI  MP ++I+ ILKMV LD I++
Sbjct: 178 LVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIED 237

Query: 170 VEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRC 229
           +EV C W LP L +F+PYLG + NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+C
Sbjct: 238 LEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQC 297

Query: 230 LQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLS 289
           LQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LS
Sbjct: 298 LQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLS 357

Query: 290 GIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNP 349
           G+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN 
Sbjct: 358 GVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNS 417

Query: 350 ICMATLENLLSHTIILKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHP 408
           I ++ L++LL H I L NL   LYP P ESY    GTL   R A + A L + +  L  P
Sbjct: 418 ISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRP 477

Query: 409 KRILFCTDNCPDHGDRSFYDLE 430
             +    + CP  GDR+FYD E
Sbjct: 478 SMVWLSANPCPHCGDRTFYDPE 499


>gi|46249369 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  386 bits (992), Expect = e-107
 Identities = 214/442 (48%), Positives = 282/442 (63%), Gaps = 12/442 (2%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRW 58
           M AF  R  + LK MVQAWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRW
Sbjct: 58  MAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRW 117

Query: 59  KLQVLDLQ-DVCENFWMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTV 109
           KLQVLDL+ +  ++FW VWS   A               K+ K         +   P+ V
Sbjct: 118 KLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEV 177

Query: 110 FVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQE 169
            V+L+LK    DE  + L+  VK+++++L LCCKKLKI  MP ++I+ ILKMV LD I++
Sbjct: 178 LVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIED 237

Query: 170 VEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRC 229
           +EV C W LP L +F+PYLG + NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+C
Sbjct: 238 LEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQC 297

Query: 230 LQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLS 289
           LQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LS
Sbjct: 298 LQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLS 357

Query: 290 GIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNP 349
           G+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN 
Sbjct: 358 GVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNS 417

Query: 350 ICMATLENLLSHTIILKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHP 408
           I ++ L++LL H I L NL   LYP P ESY    GTL   R A + A L + +  L  P
Sbjct: 418 ISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRP 477

Query: 409 KRILFCTDNCPDHGDRSFYDLE 430
             +    + CP  GDR+FYD E
Sbjct: 478 SMVWLSANPCPHCGDRTFYDPE 499


>gi|46249367 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  386 bits (992), Expect = e-107
 Identities = 214/442 (48%), Positives = 282/442 (63%), Gaps = 12/442 (2%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRW 58
           M AF  R  + LK MVQAWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRW
Sbjct: 58  MAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRW 117

Query: 59  KLQVLDLQ-DVCENFWMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTV 109
           KLQVLDL+ +  ++FW VWS   A               K+ K         +   P+ V
Sbjct: 118 KLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEV 177

Query: 110 FVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQE 169
            V+L+LK    DE  + L+  VK+++++L LCCKKLKI  MP ++I+ ILKMV LD I++
Sbjct: 178 LVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIED 237

Query: 170 VEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRC 229
           +EV C W LP L +F+PYLG + NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+C
Sbjct: 238 LEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQC 297

Query: 230 LQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLS 289
           LQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LS
Sbjct: 298 LQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLS 357

Query: 290 GIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNP 349
           G+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN 
Sbjct: 358 GVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNS 417

Query: 350 ICMATLENLLSHTIILKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHP 408
           I ++ L++LL H I L NL   LYP P ESY    GTL   R A + A L + +  L  P
Sbjct: 418 ISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRP 477

Query: 409 KRILFCTDNCPDHGDRSFYDLE 430
             +    + CP  GDR+FYD E
Sbjct: 478 SMVWLSANPCPHCGDRTFYDPE 499


>gi|5174641 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  386 bits (992), Expect = e-107
 Identities = 214/442 (48%), Positives = 282/442 (63%), Gaps = 12/442 (2%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRW 58
           M AF  R  + LK MVQAWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRW
Sbjct: 58  MAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRW 117

Query: 59  KLQVLDLQ-DVCENFWMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTV 109
           KLQVLDL+ +  ++FW VWS   A               K+ K         +   P+ V
Sbjct: 118 KLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEV 177

Query: 110 FVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQE 169
            V+L+LK    DE  + L+  VK+++++L LCCKKLKI  MP ++I+ ILKMV LD I++
Sbjct: 178 LVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIED 237

Query: 170 VEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRC 229
           +EV C W LP L +F+PYLG + NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+C
Sbjct: 238 LEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQC 297

Query: 230 LQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLS 289
           LQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LS
Sbjct: 298 LQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLS 357

Query: 290 GIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNP 349
           G+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN 
Sbjct: 358 GVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNS 417

Query: 350 ICMATLENLLSHTIILKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHP 408
           I ++ L++LL H I L NL   LYP P ESY    GTL   R A + A L + +  L  P
Sbjct: 418 ISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRP 477

Query: 409 KRILFCTDNCPDHGDRSFYDLE 430
             +    + CP  GDR+FYD E
Sbjct: 478 SMVWLSANPCPHCGDRTFYDPE 499


>gi|113865933 PRAME family member 16 [Homo sapiens]
          Length = 474

 Score =  363 bits (931), Expect = e-100
 Identities = 212/423 (50%), Positives = 256/423 (60%), Gaps = 3/423 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEA S R  EALKLMVQAWPF RLPL  L+K P LE  QAVL GLD LL Q +RPRRWKL
Sbjct: 41  MEASSMRHFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDL+DV  NFW +WS A A  C   A R +  V+D PR  E QPL VF++L  K  TL
Sbjct: 101 QVLDLRDVDGNFWTIWSGARALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTL 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DE L+ L  W+  RR L+HLCC K++   MP  + R++LK V  D IQE+E+  K  L  
Sbjct: 161 DECLSYLCRWIHYRRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNK 220

Query: 181 LTQFTPYLGHLRNLQKLVLSH-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVS 239
             +F PYL  + NL+KL L+   D   YVS +Q  + V      FL L   Q LY+  +S
Sbjct: 221 TGKFAPYLSQMSNLRKLFLAFGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKIS 278

Query: 240 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 299
            ++ HL+ LL CLK  L      +  L + D++ LSQ PS+SQLK L L  I +   +L 
Sbjct: 279 NIKEHLEHLLRCLKNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLE 338

Query: 300 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLL 359
           PL  LLEKVAATLE L L DC I DSQ+  +LPALSRC +L TF F GN      L++LL
Sbjct: 339 PLGALLEKVAATLEILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLL 398

Query: 360 SHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 419
            HT  L  L LELYPAP E     G + W   A IRAELM  +R +R PKRI F    CP
Sbjct: 399 CHTGGLSKLGLELYPAPLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCP 458

Query: 420 DHG 422
             G
Sbjct: 459 SCG 461


>gi|154800493 PRAME family member 22 [Homo sapiens]
          Length = 481

 Score =  362 bits (929), Expect = e-100
 Identities = 208/432 (48%), Positives = 273/432 (63%), Gaps = 5/432 (1%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           +EAF+ RRCE LK+MVQAWPF  LPL  L+K P LE    V+DG+D LL Q VRPRRWKL
Sbjct: 43  VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKL 102

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVL+L+DV ENFW +WS A    C   A   +  V+DCPR  E+QPL VF+++ LK + +
Sbjct: 103 QVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFM 162

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
           DE L+    WV+ RR  +HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   
Sbjct: 163 DEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCM 222

Query: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSV 238
           I+ +F+ YL  +RNL+KL +S  D  RY+ S + ++++V +F++  L+L  LQ LY+  V
Sbjct: 223 IV-EFSRYLSQMRNLRKLFIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRV 279

Query: 239 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 298
            F  GHLDQL+ CL++ L+ L +T   L + DLK L + PS+SQLK L+LS   L    L
Sbjct: 280 CFFRGHLDQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRL 339

Query: 299 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 358
            PL+ LLEKVAATL+ L L DCGI DS++  ILPALS C  L TF F GN   M  L++L
Sbjct: 340 EPLRALLEKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDL 399

Query: 359 LSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNC 418
           L HT  L NL LE YPAP+ES    G +       ++AELM+ +R +R PKRI F   +C
Sbjct: 400 LRHTGRLSNLSLETYPAPRESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSC 459

Query: 419 PDHGDRSFYDLE 430
           P  G      LE
Sbjct: 460 PCCGTSPTEQLE 471


>gi|157426839 PRAME family member 17 [Homo sapiens]
          Length = 474

 Score =  360 bits (925), Expect = 1e-99
 Identities = 211/423 (49%), Positives = 255/423 (60%), Gaps = 3/423 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEA S R  EALKLMVQAWPF RLPL  L+K P LE  QAVL GLD LL Q +RPRRWKL
Sbjct: 41  MEASSMRHFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDL+DV  NFW +WS A A  C   A   +  V+D PR  E QPL VF++L  K  TL
Sbjct: 101 QVLDLRDVDGNFWTIWSGARALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTL 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DE L+ L  W+  RR L+HLCC K++   MP  + R++LK V  D IQE+E+  K  L  
Sbjct: 161 DECLSYLCRWIHYRRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNK 220

Query: 181 LTQFTPYLGHLRNLQKLVLSH-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVS 239
             +F PYL  + NL+KL L+   D   YVS +Q  + V      FL L   Q LY+  +S
Sbjct: 221 TGKFAPYLSQMSNLRKLFLAFGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKIS 278

Query: 240 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 299
            ++ HL+ LL CLK  L      +  L + D++ LSQ PS+SQLK L L  I +   +L 
Sbjct: 279 NIKEHLEHLLRCLKNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLE 338

Query: 300 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLL 359
           PL  LLEKVAATLE L L DC I DSQ+  +LPALSRC +L TF F GN      L++LL
Sbjct: 339 PLGALLEKVAATLEILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLL 398

Query: 360 SHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 419
            HT  L  L LELYPAP E     G + W   A IRAELM  +R +R PKRI F    CP
Sbjct: 399 CHTGGLSKLGLELYPAPLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCP 458

Query: 420 DHG 422
             G
Sbjct: 459 SCG 461


>gi|153791443 PRAME family member 18 [Homo sapiens]
          Length = 479

 Score =  358 bits (918), Expect = 7e-99
 Identities = 204/421 (48%), Positives = 269/421 (63%), Gaps = 5/421 (1%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           +EAF+ RRCE LK+MVQAWPF  LPL  L+K P LE    V+DG+D LL Q VRPRRWKL
Sbjct: 41  VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVL+++DV ENFW +WS A    C   A   +  V+DCPR  E+QPL VF+++ LK +++
Sbjct: 101 QVLEMRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSV 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
           DE L+    WV+ RR  +HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   
Sbjct: 161 DEDLSFFSGWVQHRRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC- 219

Query: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSV 238
           ++ + + YL  ++NL+KL +S  D   Y+ S E + ++V +F++ FL+L  LQ LYM  +
Sbjct: 220 MVAEVSRYLSQMKNLRKLFIS--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRI 277

Query: 239 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 298
            F EG+LDQL+ CLK+ L+ L +T   L E DLK L   PS+SQLK L+LS   L    L
Sbjct: 278 RFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRL 337

Query: 299 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 358
            PL+ LLEKVAATL+ L L DCGI DS++  ILPALSRC  L TF F GN   M  L++L
Sbjct: 338 EPLRALLEKVAATLQTLFLVDCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDL 397

Query: 359 LSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNC 418
           L HT  L NL LE YPAP+ES    G +       ++AELM+ +R +R P RI F   +C
Sbjct: 398 LRHTGRLSNLSLETYPAPRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSC 457

Query: 419 P 419
           P
Sbjct: 458 P 458


>gi|194306638 PRAME family member 3 [Homo sapiens]
          Length = 481

 Score =  356 bits (913), Expect = 3e-98
 Identities = 207/432 (47%), Positives = 271/432 (62%), Gaps = 5/432 (1%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           +EAF+ RRCE LK+MVQAWPF  LPL  L+K P LE    V+DG+D LL Q VRPRR KL
Sbjct: 43  VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKL 102

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVL+L+DV ENFW +WS A    C   A   +  V+DCPR  E+QPL VF+++ LK + +
Sbjct: 103 QVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFM 162

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
           DE L+    WV+ RR  +HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   
Sbjct: 163 DEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCM 222

Query: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSV 238
           I+ +F  YL  +RNL+KL +S  D  RY+ S + ++++V +F++  L+L  LQ LY+  V
Sbjct: 223 IV-EFIRYLSQMRNLRKLFIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRV 279

Query: 239 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 298
            F  GHLDQL+ CL++ L+ L +T   L + DLK L + PS+SQLK L+LS   L    L
Sbjct: 280 CFFRGHLDQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRL 339

Query: 299 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 358
            PL+ LLEKVAATL+ L L DCGI DS++  ILPALS C  L TF F GN   M  L++L
Sbjct: 340 EPLRALLEKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDL 399

Query: 359 LSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNC 418
           L HT  L NL LE YPAP+ES    G +       ++AELM+ +R +R PKRI F   +C
Sbjct: 400 LRHTGRLSNLSLETYPAPRESLDDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSC 459

Query: 419 PDHGDRSFYDLE 430
           P  G      LE
Sbjct: 460 PCCGTSPTEQLE 471


>gi|194018546 PRAME family member 10 [Homo sapiens]
          Length = 474

 Score =  355 bits (911), Expect = 4e-98
 Identities = 206/423 (48%), Positives = 259/423 (61%), Gaps = 3/423 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFS RR EALKLMVQAWPF  LPL  L+K   LE  QAVL GLD L+ Q VRPRRWKL
Sbjct: 41  MEAFSMRRFEALKLMVQAWPFLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDL+DV ENFW +WS A    C   A   +  V+DCPRM E QPL VF++L LK  TL
Sbjct: 101 QVLDLRDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTL 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
           DE L+ L  W+  RR L+HLCC K++   MP  + R++L+ +  D IQE+EV  K  L  
Sbjct: 161 DECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNK 220

Query: 181 LTQFTPYLGHLRNLQKLVLSH-MDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVS 239
             +F PYL  + NL++L L+   +   YVS +     +    + FL L   Q LY+  +S
Sbjct: 221 TGKFAPYLSQMSNLRELFLAFGYERELYVSVQW--PCIPDLDSPFLCLYYPQMLYIKKIS 278

Query: 240 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 299
            ++ HL+ LL  LK  L     ++  L + D++ LSQ PS+SQLK L L  I +    L 
Sbjct: 279 NIKEHLEHLLRYLKNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLE 338

Query: 300 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLL 359
           PL +LLEKVAATL+ L L DC I D Q+  +LPALS C +L TF+F GN   M  L++LL
Sbjct: 339 PLGVLLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLL 398

Query: 360 SHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 419
            HT  L  L LELYPAP ES    G + W     IRAELM+ +R +R PKRI F    CP
Sbjct: 399 RHTGGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCP 458

Query: 420 DHG 422
           + G
Sbjct: 459 NCG 461


>gi|194306635 PRAME family member 19 [Homo sapiens]
          Length = 479

 Score =  354 bits (909), Expect = 8e-98
 Identities = 203/421 (48%), Positives = 268/421 (63%), Gaps = 5/421 (1%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           +EAF+ RRCE LK+MVQAWPF  LPL  L+K P LE    V+DG+D LL Q VRPRRWKL
Sbjct: 41  VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVL+++DV ENFW +WS A    C   A   +  V+DCPR  E+QPL VF+++ LK +++
Sbjct: 101 QVLEMRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSV 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
           DE L+    WV+ RR  +HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   
Sbjct: 161 DEDLSFFSGWVQHRRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC- 219

Query: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSV 238
           ++ + + YL  ++NL+KL +S  D   Y+ S E + ++V +F++ FL+L  LQ LYM  +
Sbjct: 220 MVAEVSRYLSQMKNLRKLFIS--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRI 277

Query: 239 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 298
            F EG+LDQL+ CLK+ L+ L +T   L E DLK L   PS+SQLK L+LS   L    L
Sbjct: 278 RFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRL 337

Query: 299 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 358
            PL+ LLEKVAATL+ L L DCGI  S++  ILPALSRC  L TF F GN   M  L++L
Sbjct: 338 EPLRALLEKVAATLQTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDL 397

Query: 359 LSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNC 418
           L HT  L NL LE YPAP+ES    G +       ++AELM+ +R +R P RI F   +C
Sbjct: 398 LRHTGRLSNLSLETYPAPRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSC 457

Query: 419 P 419
           P
Sbjct: 458 P 458


>gi|66954681 PRAME family member 13 [Homo sapiens]
          Length = 474

 Score =  350 bits (897), Expect = 2e-96
 Identities = 204/437 (46%), Positives = 267/437 (61%), Gaps = 4/437 (0%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAF RR  + L +MVQAWPF  LPL  L+K   LE  +A+L+GL  LLTQ  RPRRWKL
Sbjct: 41  MEAFRRRHFQTLTVMVQAWPFTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDL+DV ENFW  W  A A  CF      +   +DCPRM E QPL VF+++ LK    
Sbjct: 101 QVLDLRDVDENFWARWPGAWALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQ 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
           DE L  L  WV QRR L+HLCC KL     P +++R  LK++ L+ IQ++E+ N  W   
Sbjct: 161 DECLRYLFQWVYQRRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPR- 219

Query: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVS 239
           ++ +   YL  ++NL+KLV S    S   + E +  +VT+F++ FL+L  LQ L +  ++
Sbjct: 220 LIRKLRCYLKEMKNLRKLVFSRCHHSMSDN-ELEGRLVTKFSSVFLRLEHLQLLKIKLIT 278

Query: 240 FLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLV 299
           F  GHL+QL+ CL+  L+ L +T   LLE D+K LSQ PS+  LK L+LS + L   SL 
Sbjct: 279 FFSGHLEQLIRCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLE 338

Query: 300 PLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLL 359
           PL  LLEK+AA+LE L L+ C I  SQ++AILP LS C +L TF F  N + M  L++LL
Sbjct: 339 PLGALLEKIAASLETLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLL 398

Query: 360 SHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 419
            HT  L  L LE YPAP+ES  +   + W  FA +RAELM  +R +R PKRI      CP
Sbjct: 399 RHTSGLSKLSLETYPAPEESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCP 458

Query: 420 DHGDRSFYDLEADQYCC 436
             G     +LE    CC
Sbjct: 459 SCGSSPSEELEL-HLCC 474


>gi|12738831 PRAME family member 1 [Homo sapiens]
          Length = 474

 Score =  348 bits (894), Expect = 4e-96
 Identities = 205/438 (46%), Positives = 267/438 (60%), Gaps = 6/438 (1%)

Query: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
           MEAFSRR  + L +MVQAWPF  LPL  L+K   LE  +A+L+GL  LLTQ  RPRRWKL
Sbjct: 41  MEAFSRRHFQTLTVMVQAWPFTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKL 100

Query: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
           QVLDL+DV ENFW  W  A A  CF      +   +DCPRM E QPL VF+++ LK    
Sbjct: 101 QVLDLRDVDENFWARWPGAWALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQ 160

Query: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
           DE L  L  WV QRR L+HLCC KL     P + +R  LK++ L+ IQE+E+ N  W   
Sbjct: 161 DECLRYLFQWVYQRRGLVHLCCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSW-PR 219

Query: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYVSP-EQKKEIVTQFTTQFLKLRCLQKLYMNSV 238
           ++ +   YL  ++NL+KLV S      Y S  E +  +V +F++ FL+L  LQ L +  +
Sbjct: 220 LIRKLRCYLKEMKNLRKLVFSR--CHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLI 277

Query: 239 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 298
           +F  GHL+QL+ CL+  L+ L +T   LLE D+K LSQ PS+  LK L+LS + L   SL
Sbjct: 278 TFFSGHLEQLIRCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISL 337

Query: 299 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 358
            PL  LLEK+AA+L+ L L+ C I  SQ++AILPALSRC +L TF F  N + +  L++L
Sbjct: 338 EPLGALLEKIAASLKTLILEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDL 397

Query: 359 LSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNC 418
           L HT  L  L LE YPAP+ES  +   + W  F  +RAELM  +R +R PKRI      C
Sbjct: 398 LRHTSGLSKLSLETYPAPEESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPC 457

Query: 419 PDHGDRSFYDLEADQYCC 436
           P  G     +LE    CC
Sbjct: 458 PSCGSSPSEELEL-HLCC 474


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,451,351
Number of Sequences: 37866
Number of extensions: 707980
Number of successful extensions: 1957
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 1825
Number of HSP's gapped (non-prelim): 95
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.