Guide to the Human Genome
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Search of human proteins with 226423858

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
         (555 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]              1121   0.0  
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi...   885   0.0  
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi...   869   0.0  
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]             457   e-129
gi|66346654 proline rich 5 (renal) isoform 2 [Homo sapiens]           196   4e-50
gi|31317218 proline rich 5 (renal) isoform 1 [Homo sapiens]           196   4e-50
gi|31317214 proline rich 5 (renal) isoform 2 [Homo sapiens]           196   4e-50
gi|162287219 prune homolog 2 [Homo sapiens]                           105   1e-22
gi|56119110 family with sequence similarity 13, member A1 isofor...   105   1e-22
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...   104   2e-22
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa...   104   2e-22
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...   104   2e-22
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]            103   5e-22
gi|168480080 BCL2/adenovirus E1B 19kD interacting protein 2 [Hom...   100   5e-21
gi|29336043 caytaxin [Homo sapiens]                                   100   6e-21
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ...    96   9e-20
gi|188497642 ARHGAP15 [Homo sapiens]                                   95   2e-19
gi|51479148 Rho GTPase activating protein 20 [Homo sapiens]            95   2e-19
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]           92   1e-18
gi|228008343 BCL2/adenovirus E1B 19kD interacting protein like i...    91   2e-18
gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like i...    91   2e-18
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                91   2e-18
gi|21314774 T-cell activation Rho GTPase-activating protein isof...    91   3e-18
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi...    89   8e-18
gi|54860079 nadrin isoform 1 [Homo sapiens]                            89   8e-18
gi|54860105 nadrin isoform 2 [Homo sapiens]                            89   8e-18
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ...    89   1e-17
gi|156119615 myosin IXA [Homo sapiens]                                 89   1e-17
gi|20270373 T-cell activation Rho GTPase-activating protein isof...    88   2e-17
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]            87   3e-17

>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
          Length = 555

 Score = 1121 bits (2900), Expect = 0.0
 Identities = 555/555 (100%), Positives = 555/555 (100%)

Query: 1   MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE 60
           MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE
Sbjct: 1   MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE 60

Query: 61  GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEELQRDKAAAAAVLGAVRKRPSV 120
           GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEELQRDKAAAAAVLGAVRKRPSV
Sbjct: 61  GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEELQRDKAAAAAVLGAVRKRPSV 120

Query: 121 VPMAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYL 180
           VPMAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYL
Sbjct: 121 VPMAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYL 180

Query: 181 KYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIK 240
           KYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIK
Sbjct: 181 KYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIK 240

Query: 241 VLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPP 300
           VLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPP
Sbjct: 241 VLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPP 300

Query: 301 TKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQ 360
           TKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQ
Sbjct: 301 TKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQ 360

Query: 361 TVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSL 420
           TVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSL
Sbjct: 361 TVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSL 420

Query: 421 RVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS 480
           RVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS
Sbjct: 421 RVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS 480

Query: 481 SLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTK 540
           SLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTK
Sbjct: 481 SLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTK 540

Query: 541 PTLPPSPLMAARRRL 555
           PTLPPSPLMAARRRL
Sbjct: 541 PTLPPSPLMAARRRL 555


>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
           sapiens]
          Length = 433

 Score =  885 bits (2288), Expect = 0.0
 Identities = 433/433 (100%), Positives = 433/433 (100%)

Query: 123 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY 182
           MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY
Sbjct: 1   MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY 60

Query: 183 TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVL 242
           TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVL
Sbjct: 61  TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVL 120

Query: 243 WNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTK 302
           WNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTK
Sbjct: 121 WNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTK 180

Query: 303 TPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTV 362
           TPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTV
Sbjct: 181 TPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTV 240

Query: 363 REIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRV 422
           REIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRV
Sbjct: 241 REIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRV 300

Query: 423 TGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSL 482
           TGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSL
Sbjct: 301 TGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSL 360

Query: 483 SALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPT 542
           SALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPT
Sbjct: 361 SALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPT 420

Query: 543 LPPSPLMAARRRL 555
           LPPSPLMAARRRL
Sbjct: 421 LPPSPLMAARRRL 433


>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
           sapiens]
          Length = 464

 Score =  869 bits (2246), Expect = 0.0
 Identities = 433/464 (93%), Positives = 433/464 (93%), Gaps = 31/464 (6%)

Query: 123 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY 182
           MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY
Sbjct: 1   MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY 60

Query: 183 TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRK-------------------- 222
           TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRK                    
Sbjct: 61  TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKDGDLTMWPRLVSNSKLKRSS 120

Query: 223 -----------YKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHL 271
                      YKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHL
Sbjct: 121 HLSLPKYWDYRYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHL 180

Query: 272 KYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELI 331
           KYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELI
Sbjct: 181 KYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELI 240

Query: 332 PPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILK 391
           PPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILK
Sbjct: 241 PPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILK 300

Query: 392 TFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVS 451
           TFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVS
Sbjct: 301 TFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVS 360

Query: 452 RESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGE 511
           RESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGE
Sbjct: 361 RESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGE 420

Query: 512 HGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL 555
           HGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL
Sbjct: 421 HGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL 464


>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
          Length = 439

 Score =  457 bits (1177), Expect = e-129
 Identities = 219/382 (57%), Positives = 286/382 (74%), Gaps = 2/382 (0%)

Query: 130 LSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVE 189
           L    P+YD+ARH I++VAGDD++GR+++ FS CRMPPSH+LDH +LL YLK+TLDQYVE
Sbjct: 58  LKWDDPYYDIARHQIVEVAGDDKYGRKIIVFSACRMPPSHQLDHSKLLGYLKHTLDQYVE 117

Query: 190 NDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPL 249
           +DYT++Y H+GL S NKPSL WL+ AY+EFDRKYKKN+KALY+VHPT FIK L  + KPL
Sbjct: 118 SDYTLLYLHHGLTSDNKPSLSWLRDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPL 177

Query: 250 ISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRPP 309
           IS KFG+K+ Y NYLSEL EH+K +QL IP +VL+YD+ L+S  +     P K  PPRPP
Sbjct: 178 ISFKFGQKIFYVNYLSELSEHVKLEQLGIPRQVLKYDDFLKSTQKSPATAP-KPMPPRPP 236

Query: 310 LPTQQFGVSLQYLKDKN-QGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRL 368
           LP QQFGVSLQ+L++KN + E IP VLR TV YL+   L TEG+FRRSA+ Q VRE+Q+ 
Sbjct: 237 LPNQQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQK 296

Query: 369 YNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI 428
           YN G PV+FD Y ++H+PAVILKTFLRELP+PLLTF  Y  ++G   ++ S RV    Q+
Sbjct: 297 YNMGLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQV 356

Query: 429 LRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPL 488
           L++LPE NY VLR+L  FL  +S  S  NKM ++NLA VFG NL+W      +L A+ P+
Sbjct: 357 LQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPI 416

Query: 489 NMFTELLIEYYEKIFSTPEAPG 510
           N FT+ L+++  ++F +P+  G
Sbjct: 417 NTFTKFLLDHQGELFPSPDPSG 438


>gi|66346654 proline rich 5 (renal) isoform 2 [Homo sapiens]
          Length = 379

 Score =  196 bits (499), Expect = 4e-50
 Identities = 98/98 (100%), Positives = 98/98 (100%)

Query: 1  MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE 60
          MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE
Sbjct: 1  MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE 60

Query: 61 GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYE 98
          GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYE
Sbjct: 61 GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYE 98


>gi|31317218 proline rich 5 (renal) isoform 1 [Homo sapiens]
          Length = 388

 Score =  196 bits (499), Expect = 4e-50
 Identities = 98/98 (100%), Positives = 98/98 (100%)

Query: 1   MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE 60
           MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE
Sbjct: 10  MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE 69

Query: 61  GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYE 98
           GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYE
Sbjct: 70  GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYE 107


>gi|31317214 proline rich 5 (renal) isoform 2 [Homo sapiens]
          Length = 379

 Score =  196 bits (499), Expect = 4e-50
 Identities = 98/98 (100%), Positives = 98/98 (100%)

Query: 1  MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE 60
          MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE
Sbjct: 1  MSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNE 60

Query: 61 GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYE 98
          GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYE
Sbjct: 61 GVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYE 98


>gi|162287219 prune homolog 2 [Homo sapiens]
          Length = 3088

 Score =  105 bits (261), Expect = 1e-22
 Identities = 51/142 (35%), Positives = 81/142 (57%), Gaps = 4/142 (2%)

Query: 157  VVTFSCCRMPPSHELDHQRLLE----YLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWL 212
            ++ F+ C +P S   D+  ++E    Y+  TL+  V  DY IVY +     R  P LGW+
Sbjct: 2919 IIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWM 2978

Query: 213  QSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLK 272
            +  Y+  DR+ +KNLK+  +VHP+ FI+ +  + +P IS KF  K+ Y N LSEL   + 
Sbjct: 2979 KKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIP 3038

Query: 273  YDQLVIPPEVLRYDEKLQSLHE 294
             D + IP  +++ DE+L+   E
Sbjct: 3039 MDCIHIPESIIKLDEELREASE 3060


>gi|56119110 family with sequence similarity 13, member A1 isoform a
           [Homo sapiens]
          Length = 1023

 Score =  105 bits (261), Expect = 1e-22
 Identities = 65/200 (32%), Positives = 103/200 (51%), Gaps = 2/200 (1%)

Query: 315 FGVSLQYLKDKNQGEL-IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGK 373
           FGVSLQ L+ +   E  IP V+   V YL + GL  EGLFR + +V+ V +++  +  G 
Sbjct: 41  FGVSLQELERQGLTENGIPAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGV 100

Query: 374 PVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGI-TCVESSLRVTGCRQILRSL 432
           PV     GD+   A +LK FLRELP  L+T     + + +     + ++ +  R +++ L
Sbjct: 101 PVELGKDGDVCSAASLLKLFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLIKEL 160

Query: 433 PEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFT 492
           P+ +Y +L+YL  FL  V++  + N+MN  NLA VFG N      G+  +      N   
Sbjct: 161 PDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVFGPNCFHVPPGLEGMKEQDLCNKIM 220

Query: 493 ELLIEYYEKIFSTPEAPGEH 512
             ++E Y  +F       +H
Sbjct: 221 AKILENYNTLFEVEYTENDH 240


>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
           sapiens]
          Length = 653

 Score =  104 bits (259), Expect = 2e-22
 Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 6/186 (3%)

Query: 324 DKNQGELIPPVL-RFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGD 382
           +K  G  + P+L    V ++R++GL+ EGLFR       V+E+Q  ++ G+  +FD   D
Sbjct: 49  EKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTD 108

Query: 383 IHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI---LRSLPEHNYVV 439
           +H  A +LK +LRELP+P++ +  YE  L    + S     G +++   ++SLP  NY +
Sbjct: 109 VHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNL 168

Query: 440 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIE 497
           L+Y+  FL  V   S  NKM+  NLA VFG N++ P     ++ +   V +     ++I 
Sbjct: 169 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 228

Query: 498 YYEKIF 503
            ++ +F
Sbjct: 229 KHDCLF 234


>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
           sapiens]
          Length = 655

 Score =  104 bits (259), Expect = 2e-22
 Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 6/186 (3%)

Query: 324 DKNQGELIPPVL-RFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGD 382
           +K  G  + P+L    V ++R++GL+ EGLFR       V+E+Q  ++ G+  +FD   D
Sbjct: 51  EKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTD 110

Query: 383 IHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI---LRSLPEHNYVV 439
           +H  A +LK +LRELP+P++ +  YE  L    + S     G +++   ++SLP  NY +
Sbjct: 111 VHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNL 170

Query: 440 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIE 497
           L+Y+  FL  V   S  NKM+  NLA VFG N++ P     ++ +   V +     ++I 
Sbjct: 171 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 230

Query: 498 YYEKIF 503
            ++ +F
Sbjct: 231 KHDCLF 236


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score =  104 bits (259), Expect = 2e-22
 Identities = 60/186 (32%), Positives = 102/186 (54%), Gaps = 6/186 (3%)

Query: 324 DKNQGELIPPVL-RFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGD 382
           +K  G  + P+L    V ++R++GL+ EGLFR       V+E+Q  ++ G+  +FD   D
Sbjct: 144 EKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTD 203

Query: 383 IHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQI---LRSLPEHNYVV 439
           +H  A +LK +LRELP+P++ +  YE  L    + S     G +++   ++SLP  NY +
Sbjct: 204 VHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNL 263

Query: 440 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIE 497
           L+Y+  FL  V   S  NKM+  NLA VFG N++ P     ++ +   V +     ++I 
Sbjct: 264 LKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMIS 323

Query: 498 YYEKIF 503
            ++ +F
Sbjct: 324 KHDCLF 329


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score =  103 bits (256), Expect = 5e-22
 Identities = 62/186 (33%), Positives = 98/186 (52%), Gaps = 5/186 (2%)

Query: 330 LIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVI 389
           L P ++   V ++RE+GL  EGLFR       VR++Q  ++ G+   FD   D+H  A +
Sbjct: 171 LAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASL 230

Query: 390 LKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILR---SLPEHNYVVLRYLMGF 446
           LK +LRELP+P++ F  YE  L    + +     G  ++ +   +LP+ NY +LRY+  F
Sbjct: 231 LKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKF 290

Query: 447 LHAVSRESIFNKMNSSNLACVFGLNLIWP--SQGVSSLSALVPLNMFTELLIEYYEKIFS 504
           L  V   S  NKM+  NLA VFG N++ P     V+ +     +     +LI  + ++F+
Sbjct: 291 LDEVQAYSNVNKMSVQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLFT 350

Query: 505 TPEAPG 510
            P   G
Sbjct: 351 APVPEG 356


>gi|168480080 BCL2/adenovirus E1B 19kD interacting protein 2 [Homo
           sapiens]
          Length = 435

 Score =  100 bits (248), Expect = 5e-21
 Identities = 53/137 (38%), Positives = 85/137 (62%), Gaps = 4/137 (2%)

Query: 157 VVTFSCCRMPPSHELDHQRLLEYL-KY---TLDQYVENDYTIVYFHYGLNSRNKPSLGWL 212
           +V F+ C MP S + +++ L++ L KY   TL+  V  +Y IVY +     R  PSLGWL
Sbjct: 288 IVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWL 347

Query: 213 QSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLK 272
           +  Y++ DR+ +KNLK+L +VHP+ FI+ L  + +P IS KF +K+ Y   L+EL E + 
Sbjct: 348 RKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVP 407

Query: 273 YDQLVIPPEVLRYDEKL 289
            + + IP  + + D++L
Sbjct: 408 MEYVGIPECIKQVDQEL 424


>gi|29336043 caytaxin [Homo sapiens]
          Length = 371

 Score = 99.8 bits (247), Expect = 6e-21
 Identities = 57/171 (33%), Positives = 93/171 (54%), Gaps = 9/171 (5%)

Query: 135 PFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLE----YLKYTLDQYVEN 190
           P+  V  HG     G +     ++ F+ C +P S   D+  ++E    Y+  +L+  V  
Sbjct: 173 PYMKVVTHGGYYGEGLNA----IIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAE 228

Query: 191 DYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLI 250
           DY IVY +     R  P +GWL+  Y+  DR+ +KNLK+L +VHP+ FI+ +  I +P I
Sbjct: 229 DYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFI 288

Query: 251 SHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRY-DEKLQSLHEGRTPPP 300
           S KF  K+ Y + L +L + +  + + IP  VL+Y +E+L++  E   P P
Sbjct: 289 SVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQP 339


>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
           [Homo sapiens]
          Length = 1099

 Score = 95.9 bits (237), Expect = 9e-20
 Identities = 77/262 (29%), Positives = 126/262 (48%), Gaps = 21/262 (8%)

Query: 263 YLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGR------TPPPTKTPPP---RPPLPTQ 313
           Y ++  E++    L+   +  ++D   Q+L EG       T PP   P P   R P P  
Sbjct: 439 YFTKFKEYVNGSNLITKLQA-KHDLLKQTLGEGERAECGTTRPPCLPPKPQKMRRPRPLS 497

Query: 314 QFGVSL------QYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQR 367
            +   L       ++KD   G+ IP V+   + Y+   GL+ +G+FR   S   V +I+ 
Sbjct: 498 VYSHKLFNGSMEAFIKDS--GQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKN 555

Query: 368 LYNQGKPVNFDDYG--DIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSL-RVTG 424
            + +G+    DD    DI+  A +LK + R L  PL   + ++ ++    +E+   RV  
Sbjct: 556 SFERGEDPLVDDQNERDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQ 615

Query: 425 CRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSA 484
            +QIL +LP    VV+RYL  FL+ +S+ S  N M+  NLA  FG  L+    G   +S 
Sbjct: 616 IQQILVTLPRVVIVVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSC 675

Query: 485 LVPLNMFTELLIEYYEKIFSTP 506
              +N   + +I ++E IF +P
Sbjct: 676 QAHINEVIKTIIIHHEAIFPSP 697


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 57/213 (26%), Positives = 113/213 (53%), Gaps = 5/213 (2%)

Query: 299 PPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSAS 358
           P  KT   +  +  Q FG  L  + ++ +   +P  ++  +  + ++GL  +G++R S +
Sbjct: 263 PSLKTLQEKGLIKDQIFGSHLHKVCER-ENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGN 321

Query: 359 VQTVREIQRLYNQGKPVNFDD--YGDIHIPAVILKTFLRELPQPLLTFQAYEQIL-GITC 415
           + T+++++ + NQ + +N DD  + DIH+    LK F RELP+PL  +  +EQ +  I  
Sbjct: 322 LATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKK 381

Query: 416 VESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP 475
            +++ R+   + +++ LP  N   ++ L G L  +  ++  N M++ +L  VFG  L+  
Sbjct: 382 QDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRA 441

Query: 476 SQGVSSLSA-LVPLNMFTELLIEYYEKIFSTPE 507
                +++  +V  N   EL++  Y KIF + E
Sbjct: 442 ENETGNMAIHMVYQNQIAELMLSEYSKIFGSEE 474


>gi|51479148 Rho GTPase activating protein 20 [Homo sapiens]
          Length = 1191

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 57/171 (33%), Positives = 95/171 (55%), Gaps = 5/171 (2%)

Query: 306 PRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREI 365
           P  P+P Q FG+SL  + + +   L  PVL   + +L +KG  T+G+FR+SA+V++ RE+
Sbjct: 354 PTSPMPGQLFGISLPNICENDN--LPKPVLDM-LFFLNQKGPLTKGIFRQSANVKSCREL 410

Query: 366 QRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCV-ESSLRVTG 424
           +   N G  V+ D    I + A +LK FLR +P  + +   Y+  + +        ++  
Sbjct: 411 KEKLNSGVEVHLD-CESIFVIASVLKDFLRNIPGSIFSSDLYDHWVSVMDQGNDEEKINT 469

Query: 425 CRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWP 475
            +++L  LP  N V+LRYL G LH + + S  N+M + NLA     +++WP
Sbjct: 470 VQRLLDQLPRANVVLLRYLFGVLHNIEQHSSSNQMTAFNLAVCVAPSILWP 520


>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
          Length = 1397

 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 58/203 (28%), Positives = 103/203 (50%), Gaps = 6/203 (2%)

Query: 315  FGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGK- 373
            FGV L+  +   + + +P ++      +  +GL + G++R   +   V  +Q   N+G  
Sbjct: 809  FGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPG 868

Query: 374  PVNFDD--YGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSL-RVTGCRQILR 430
             +N  D  + D+++ + +LK+F R+LP+PL T   Y   +    +E +  R+   R+++R
Sbjct: 869  DINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIR 928

Query: 431  SLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQG--VSSLSALVPL 488
             LP H Y  L++L+G L  ++  S  NKM   NLA VFG  L+  S+      ++ +   
Sbjct: 929  DLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDR 988

Query: 489  NMFTELLIEYYEKIFSTPEAPGE 511
                E LI++ +  FS  E  GE
Sbjct: 989  YKIVETLIQHSDWFFSDEEDKGE 1011


>gi|228008343 BCL2/adenovirus E1B 19kD interacting protein like
           isoform b [Homo sapiens]
          Length = 275

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 51/164 (31%), Positives = 85/164 (51%), Gaps = 8/164 (4%)

Query: 130 LSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMP----PSHELDHQRLLEYLKYTLD 185
           ++   P+  V  HG     G +     V+ F+ C +P    P++    + L  Y+  TL+
Sbjct: 110 MTVIEPYKKVLSHGGYHGDGLNA----VILFASCYLPRSSIPNYTYVMEHLFRYMVGTLE 165

Query: 186 QYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNI 245
             V  +Y +V+   G +    P L W++  Y+  DR+ +KNL+AL VVH T ++K    +
Sbjct: 166 LLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLAL 225

Query: 246 LKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKL 289
           L+P IS KF +K+ + + L EL + +  DQ+ IP  V + D  L
Sbjct: 226 LRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQLDRDL 269


>gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like
           isoform a [Homo sapiens]
          Length = 357

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 51/164 (31%), Positives = 85/164 (51%), Gaps = 8/164 (4%)

Query: 130 LSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMP----PSHELDHQRLLEYLKYTLD 185
           ++   P+  V  HG     G +     V+ F+ C +P    P++    + L  Y+  TL+
Sbjct: 192 MTVIEPYKKVLSHGGYHGDGLNA----VILFASCYLPRSSIPNYTYVMEHLFRYMVGTLE 247

Query: 186 QYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNI 245
             V  +Y +V+   G +    P L W++  Y+  DR+ +KNL+AL VVH T ++K    +
Sbjct: 248 LLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLAL 307

Query: 246 LKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKL 289
           L+P IS KF +K+ + + L EL + +  DQ+ IP  V + D  L
Sbjct: 308 LRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQLDRDL 351


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 61/183 (33%), Positives = 95/183 (51%), Gaps = 10/183 (5%)

Query: 297 TPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRS 356
           +P  T T  PR       +GVSL     +   E+  P+    V  L  +G++ EGLFR +
Sbjct: 262 SPSMTATHFPRV------YGVSLATHLQELGREIALPI-EACVMMLLSEGMKEEGLFRLA 314

Query: 357 ASVQTVREIQRLYNQGKPVNFDDY-GDIHIPAVILKTFLRELPQPLLTFQAYEQILGITC 415
           A    ++ +++      P + +++  D H  A  LK++LRELP+PL+TF  Y+  +    
Sbjct: 315 AGASVLKRLKQTM-ASDPHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAAS 373

Query: 416 V-ESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIW 474
           + E   R+   +++   LP  N   LRYLM FL  ++ E   NKM  SN+A V G NL+W
Sbjct: 374 LKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLW 433

Query: 475 PSQ 477
           P +
Sbjct: 434 PPE 436


>gi|21314774 T-cell activation Rho GTPase-activating protein isoform
           b [Homo sapiens]
          Length = 731

 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 55/172 (31%), Positives = 97/172 (56%), Gaps = 3/172 (1%)

Query: 329 ELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAV 388
           + +P  ++  +T L  KG  TEG+FRR+A+ +  +E++   N G  V+ +    +H+ AV
Sbjct: 98  DTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL-PVHLLAV 156

Query: 389 ILKTFLRELPQPLLTFQAYEQILG-ITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFL 447
           + K FLR +P+ LL+   +E+ +G +   +   R+   +Q+   LP  N ++L++L+  L
Sbjct: 157 VFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVL 216

Query: 448 HAVSRESIFNKMNSSNLACVFGLNLIWPSQGVS-SLSALVPLNMFTELLIEY 498
           H +S+ S  N+M+SSNLA   G N++      S S  A   LN   + L+E+
Sbjct: 217 HLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEF 268


>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
           sapiens]
          Length = 1085

 Score = 89.4 bits (220), Expect = 8e-18
 Identities = 71/259 (27%), Positives = 125/259 (48%), Gaps = 21/259 (8%)

Query: 263 YLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGR------TPPPTKTPPP---RPPLPTQ 313
           Y  +L E+L+   L+   +  ++D   ++L EG       T PP   P P   R   P  
Sbjct: 439 YFMKLREYLEGSNLITKLQA-KHDLLQRTLGEGHRAEYMTTRPPNVPPKPQKHRKSRPRS 497

Query: 314 QFGVSL------QYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQR 367
           Q+   L       ++KD   G++IP ++   + ++   GL+ +G+FR S S   V +I+ 
Sbjct: 498 QYNTKLFNGDLETFVKDS--GQVIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKN 555

Query: 368 LYNQGKPVNFDDYG--DIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSL-RVTG 424
            + +G+    DD    DI+  A +LK + R L  PL   + +  ++    +++   R   
Sbjct: 556 SFERGENPLADDQSNHDINSVAGVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERALH 615

Query: 425 CRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSA 484
            R++L +LP    +V+RYL  FL+ +S+ S  N M+  NLA  FG  L+   +    +S 
Sbjct: 616 IRKLLLTLPRSVLIVMRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQDQVSC 675

Query: 485 LVPLNMFTELLIEYYEKIF 503
              +N   + +I ++E IF
Sbjct: 676 QAHVNEIIKTIIIHHETIF 694


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 89.4 bits (220), Expect = 8e-18
 Identities = 54/161 (33%), Positives = 86/161 (53%), Gaps = 2/161 (1%)

Query: 315 FGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKP 374
           FG  L+    ++  E+  P+    V  L E G++ EGLFR  A    +++++   +    
Sbjct: 250 FGTPLEEHLKRSGREIALPI-EACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTS 308

Query: 375 VNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESS-LRVTGCRQILRSLP 433
              + Y D H  A  LK++LRELP+PL+TF  YE+   +  V+    ++    +  + LP
Sbjct: 309 HLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLP 368

Query: 434 EHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIW 474
             N+V  RYL+ FL  +++ S  NKM  SN+A V G NL+W
Sbjct: 369 PQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLW 409


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 89.4 bits (220), Expect = 8e-18
 Identities = 54/161 (33%), Positives = 86/161 (53%), Gaps = 2/161 (1%)

Query: 315 FGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKP 374
           FG  L+    ++  E+  P+    V  L E G++ EGLFR  A    +++++   +    
Sbjct: 250 FGTPLEEHLKRSGREIALPI-EACVMLLLETGMKEEGLFRIGAGASKLKKLKAALDCSTS 308

Query: 375 VNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESS-LRVTGCRQILRSLP 433
              + Y D H  A  LK++LRELP+PL+TF  YE+   +  V+    ++    +  + LP
Sbjct: 309 HLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQVASVQDQDKKLQDLWRTCQKLP 368

Query: 434 EHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIW 474
             N+V  RYL+ FL  +++ S  NKM  SN+A V G NL+W
Sbjct: 369 PQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGPNLLW 409


>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
           [Homo sapiens]
          Length = 1075

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 58/187 (31%), Positives = 99/187 (52%), Gaps = 3/187 (1%)

Query: 323 KDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYG- 381
           ++++ G+ IP V+   + Y+   GL+ +G+FR   S   V +I+  + +G+    DD   
Sbjct: 487 RNQDSGQAIPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNE 546

Query: 382 -DIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSL-RVTGCRQILRSLPEHNYVV 439
            DI+  A +LK + R L  PL   + ++ ++    +E+   RV   +QIL +LP    VV
Sbjct: 547 RDINSVAGVLKLYFRGLENPLFPKERFQDLISTIKLENPAERVHQIQQILVTLPRVVIVV 606

Query: 440 LRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYY 499
           +RYL  FL+ +S+ S  N M+  NLA  FG  L+    G   +S    +N   + +I ++
Sbjct: 607 MRYLFAFLNHLSQYSDENMMDPYNLAICFGPTLMHIPDGQDPVSCQAHINEVIKTIIIHH 666

Query: 500 EKIFSTP 506
           E IF +P
Sbjct: 667 EAIFPSP 673


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 54/163 (33%), Positives = 91/163 (55%), Gaps = 5/163 (3%)

Query: 308  PPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREI-Q 366
            P L ++QFGV L  L  +++   +P V+   + Y+   GL TEG++R+S S   ++E+ Q
Sbjct: 2054 PELSSRQFGVELSRLTSEDR--TVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQ 2111

Query: 367  RLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQIL-GITCVESSLRVTGC 425
             L    + VN DDY +IH+ A + K +LR+LP PL+TF+ YE+ L  +   E    + G 
Sbjct: 2112 GLDTDAESVNLDDY-NIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGV 2170

Query: 426  RQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVF 468
              ++  L   +   L  L+  L  ++ +   N+M+++ LA VF
Sbjct: 2171 YSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVF 2213


>gi|20270373 T-cell activation Rho GTPase-activating protein isoform
           c [Homo sapiens]
          Length = 266

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 48/146 (32%), Positives = 87/146 (59%), Gaps = 2/146 (1%)

Query: 329 ELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAV 388
           + +P  ++  +T L  KG  TEG+FRR+A+ +  +E++   N G  V+ +    +H+ AV
Sbjct: 98  DTLPRPIQDILTILCLKGPSTEGIFRRAANEKARKELKEELNSGDAVDLERL-PVHLLAV 156

Query: 389 ILKTFLRELPQPLLTFQAYEQILG-ITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFL 447
           + K FLR +P+ LL+   +E+ +G +   +   R+   +Q+   LP  N ++L++L+  L
Sbjct: 157 VFKDFLRSIPRKLLSSDLFEEWMGALEMQDEEDRIEALKQVADKLPRPNLLLLKHLVYVL 216

Query: 448 HAVSRESIFNKMNSSNLACVFGLNLI 473
           H +S+ S  N+M+SSNLA   G N++
Sbjct: 217 HLISKNSEVNRMDSSNLAICIGPNML 242


>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
          Length = 846

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 53/194 (27%), Positives = 96/194 (49%), Gaps = 4/194 (2%)

Query: 313 QQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQG 372
           Q FG +L  L  +  G  +P  ++  + ++ E GL  +G++R S ++  +++++   N  
Sbjct: 652 QVFGSNLANLCQRENGT-VPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHD 710

Query: 373 KPVNFDD--YGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILR 430
           + ++ +D  + DIH+    LK F RELP+PL TF  +   +     E   RV   + ++R
Sbjct: 711 EKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIR 770

Query: 431 SLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSA-LVPLN 489
            LP+ N   ++ L   L  V      N+M   ++A VFG  L+ P +   +++   V  N
Sbjct: 771 QLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQN 830

Query: 490 MFTELLIEYYEKIF 503
              EL++     IF
Sbjct: 831 QIVELILLELSSIF 844


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,030,257
Number of Sequences: 37866
Number of extensions: 1138986
Number of successful extensions: 7754
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 7095
Number of HSP's gapped (non-prelim): 539
length of query: 555
length of database: 18,247,518
effective HSP length: 107
effective length of query: 448
effective length of database: 14,195,856
effective search space: 6359743488
effective search space used: 6359743488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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