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Search of human proteins with 226371725
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
(777 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226371725 FCH domain only 2 isoform b [Homo sapiens] 1536 0.0
gi|226371723 FCH domain only 2 isoform a [Homo sapiens] 1519 0.0
gi|239049457 FCH domain only 1 isoform b [Homo sapiens] 684 0.0
gi|29789054 FCH domain only 1 isoform b [Homo sapiens] 684 0.0
gi|239049440 FCH domain only 1 isoform a [Homo sapiens] 674 0.0
gi|239049540 FCH domain only 1 isoform c [Homo sapiens] 604 e-173
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote... 480 e-135
gi|165905601 proline-serine-threonine phosphatase interacting pr... 81 3e-15
gi|20149528 proline-serine-threonine phosphatase interacting pro... 81 4e-15
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens] 77 5e-14
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 77 5e-14
gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens] 77 5e-14
gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens] 77 5e-14
gi|148747351 protein kinase C and casein kinase substrate in neu... 60 1e-08
gi|24308229 protein kinase C and casein kinase substrate in neur... 55 2e-07
gi|38044112 restin isoform b [Homo sapiens] 52 3e-06
gi|4506751 restin isoform a [Homo sapiens] 52 3e-06
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 50 8e-06
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 50 8e-06
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 49 1e-05
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 49 1e-05
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 49 1e-05
gi|24430146 nucleoporin 153kDa [Homo sapiens] 49 2e-05
gi|55750053 atrophin-1 [Homo sapiens] 47 5e-05
gi|55750041 atrophin-1 [Homo sapiens] 47 5e-05
gi|19224660 protein kinase C and casein kinase substrate in neur... 47 5e-05
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap... 47 9e-05
gi|91982772 mucin 17 [Homo sapiens] 47 9e-05
gi|21070997 stromal interaction molecule 1 precursor [Homo sapiens] 46 1e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 46 2e-04
>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
Length = 777
Score = 1536 bits (3978), Expect = 0.0
Identities = 777/777 (100%), Positives = 777/777 (100%)
Query: 1 MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSA 60
MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSA
Sbjct: 1 MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSA 60
Query: 61 SNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVA 120
SNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVA
Sbjct: 61 SNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVA 120
Query: 121 GTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLY 180
GTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLY
Sbjct: 121 GTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLY 180
Query: 181 VEKYALAKADFEQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEEC 240
VEKYALAKADFEQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEEC
Sbjct: 181 VEKYALAKADFEQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEEC 240
Query: 241 DTASAVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQND 300
DTASAVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQND
Sbjct: 241 DTASAVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQND 300
Query: 301 TKENHFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNITLSPAISRH 360
TKENHFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNITLSPAISRH
Sbjct: 301 TKENHFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNITLSPAISRH 360
Query: 361 SPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTT 420
SPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTT
Sbjct: 361 SPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTT 420
Query: 421 PLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSIS 480
PLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSIS
Sbjct: 421 PLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSIS 480
Query: 481 SSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDM 540
SSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDM
Sbjct: 481 SSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDM 540
Query: 541 TMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQ 600
TMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQ
Sbjct: 541 TMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQ 600
Query: 601 AVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYN 660
AVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYN
Sbjct: 601 AVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYN 660
Query: 661 PEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSL 720
PEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSL
Sbjct: 661 PEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSL 720
Query: 721 RAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYLADC 777
RAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYLADC
Sbjct: 721 RAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYLADC 777
>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
Length = 810
Score = 1519 bits (3934), Expect = 0.0
Identities = 777/810 (95%), Positives = 777/810 (95%), Gaps = 33/810 (4%)
Query: 1 MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSA 60
MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSA
Sbjct: 1 MVMAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSA 60
Query: 61 SNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVA 120
SNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVA
Sbjct: 61 SNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVA 120
Query: 121 GTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLY 180
GTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLY
Sbjct: 121 GTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLY 180
Query: 181 VEKYALAKADFEQKMTETAQ---------------------------------VHEEFIN 207
VEKYALAKADFEQKMTETAQ VHEEFIN
Sbjct: 181 VEKYALAKADFEQKMTETAQKFQDIEETHLIHIKEIIGSLSNAIKEIHLQIGQVHEEFIN 240
Query: 208 NMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKPRKRKTFALPGIIKKEK 267
NMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKPRKRKTFALPGIIKKEK
Sbjct: 241 NMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKPRKRKTFALPGIIKKEK 300
Query: 268 DAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIEIK 327
DAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIEIK
Sbjct: 301 DAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIEIK 360
Query: 328 PMHPNNSHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTKSKPSAPPNEKG 387
PMHPNNSHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTKSKPSAPPNEKG
Sbjct: 361 PMHPNNSHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTKSKPSAPPNEKG 420
Query: 388 TSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGI 447
TSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGI
Sbjct: 421 TSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGI 480
Query: 448 NEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQ 507
NEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQ
Sbjct: 481 NEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQ 540
Query: 508 DTLPVAVALTESVNAYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKN 567
DTLPVAVALTESVNAYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKN
Sbjct: 541 DTLPVAVALTESVNAYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKN 600
Query: 568 ISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQ 627
ISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQ
Sbjct: 601 ISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQ 660
Query: 628 VSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQ 687
VSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQ
Sbjct: 661 VSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQ 720
Query: 688 SLPPAIWNAEQMKAFWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTL 747
SLPPAIWNAEQMKAFWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTL
Sbjct: 721 SLPPAIWNAEQMKAFWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTL 780
Query: 748 SGVDFELVGTGYRLSLIKKRFATGRYLADC 777
SGVDFELVGTGYRLSLIKKRFATGRYLADC
Sbjct: 781 SGVDFELVGTGYRLSLIKKRFATGRYLADC 810
>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 684 bits (1765), Expect = 0.0
Identities = 389/897 (43%), Positives = 541/897 (60%), Gaps = 130/897 (14%)
Query: 3 MAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASN 62
M+YF E+FWGEKN GF+VLYH++K G ISTKELADF+RERATIEE YS++M KL+K ASN
Sbjct: 1 MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
Query: 63 YSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGT 122
+ +GTFAP+W+VF+ S++KLA CHL+L RKLQ+LIK+V +YGEEQ+K+HKK KEEV T
Sbjct: 61 GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
Query: 123 LEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVE 182
L+AVQ + ++Q L KS+ENY +C++QERL++E +Q+E++KA K+KKA ++ + VE
Sbjct: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180
Query: 183 KYALAKADFEQKMTETA---------------------------------QVHEEFINNM 209
KY A+ADFEQKM ++A QVHEEF N+
Sbjct: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240
Query: 210 ANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKP-RKRKTFALPGIIKKEKD 268
N +VE L++KFAESKGTG+E+PG ++FE A+ E +K R K F LPG+ ++E++
Sbjct: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300
Query: 269 AE---SVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIE 325
E +V+ + DS P+VDEEG++++P+ QN T E +SSSDSD +DEEP+K+ +
Sbjct: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360
Query: 326 IKPMHPN-NSHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTK-SKPSAPP 383
IKP + A+ +L+ + G++ L P M R+ S + K +P + P
Sbjct: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGG----TMKRHSSRDAAGKPQRPRSAP 416
Query: 384 NEKGTSDLLAWDP-----LFGPSLDS---------SSSSSLTSSSS-------------- 415
++ L + LFGP L+S SSS TSS S
Sbjct: 417 RTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSG 476
Query: 416 -----------------ARPTTPLSVGT----------IVPPPRPASRPKLTSG------ 442
RP TP S + I PP P S L S
Sbjct: 477 LDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGL 536
Query: 443 -KLSGINEIPRPFSPPVTSNTSPPP--------AAPLARAE-------SSSSISSSASLS 486
L+G + +P P P + PP + PL R+ S S + SSA+ +
Sbjct: 537 EALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAST 596
Query: 487 AANTPTV------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDM 540
A P+ GVSRGPSPV LG+QD LP+A A TE V+AYF+G P+ C+ ++TG++
Sbjct: 597 ALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPS-CLARVTGEL 655
Query: 541 TMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQ 600
TM+FP+GI++VF+ P P VL FR+ + + +E PNA L+FSDPSQ D TKDFW+NM
Sbjct: 656 TMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMA 715
Query: 601 AVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYN 660
A+T L++ +EQNP ASYYNV +L+YQ S G QS PL L+ +W+C A+ T + V+Y Y
Sbjct: 716 ALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYR 775
Query: 661 PEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSL 720
P A P+ L+N+Q+++PV VTN++ P A WN E+ + W+L +SE GGSG L
Sbjct: 776 PGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEA---GGSGRL 832
Query: 721 RAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYLADC 777
A ++ GPS P+ +A QF SEG+TLSGVD ELVG+GYR+SL+K+RFATG YL C
Sbjct: 833 SASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889
>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 684 bits (1765), Expect = 0.0
Identities = 389/897 (43%), Positives = 541/897 (60%), Gaps = 130/897 (14%)
Query: 3 MAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASN 62
M+YF E+FWGEKN GF+VLYH++K G ISTKELADF+RERATIEE YS++M KL+K ASN
Sbjct: 1 MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
Query: 63 YSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGT 122
+ +GTFAP+W+VF+ S++KLA CHL+L RKLQ+LIK+V +YGEEQ+K+HKK KEEV T
Sbjct: 61 GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
Query: 123 LEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVE 182
L+AVQ + ++Q L KS+ENY +C++QERL++E +Q+E++KA K+KKA ++ + VE
Sbjct: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180
Query: 183 KYALAKADFEQKMTETA---------------------------------QVHEEFINNM 209
KY A+ADFEQKM ++A QVHEEF N+
Sbjct: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240
Query: 210 ANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKP-RKRKTFALPGIIKKEKD 268
N +VE L++KFAESKGTG+E+PG ++FE A+ E +K R K F LPG+ ++E++
Sbjct: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300
Query: 269 AE---SVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIE 325
E +V+ + DS P+VDEEG++++P+ QN T E +SSSDSD +DEEP+K+ +
Sbjct: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360
Query: 326 IKPMHPN-NSHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTK-SKPSAPP 383
IKP + A+ +L+ + G++ L P M R+ S + K +P + P
Sbjct: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGG----TMKRHSSRDAAGKPQRPRSAP 416
Query: 384 NEKGTSDLLAWDP-----LFGPSLDS---------SSSSSLTSSSS-------------- 415
++ L + LFGP L+S SSS TSS S
Sbjct: 417 RTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSG 476
Query: 416 -----------------ARPTTPLSVGT----------IVPPPRPASRPKLTSG------ 442
RP TP S + I PP P S L S
Sbjct: 477 LDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGL 536
Query: 443 -KLSGINEIPRPFSPPVTSNTSPPP--------AAPLARAE-------SSSSISSSASLS 486
L+G + +P P P + PP + PL R+ S S + SSA+ +
Sbjct: 537 EALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAST 596
Query: 487 AANTPTV------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDM 540
A P+ GVSRGPSPV LG+QD LP+A A TE V+AYF+G P+ C+ ++TG++
Sbjct: 597 ALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPS-CLARVTGEL 655
Query: 541 TMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQ 600
TM+FP+GI++VF+ P P VL FR+ + + +E PNA L+FSDPSQ D TKDFW+NM
Sbjct: 656 TMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMA 715
Query: 601 AVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYN 660
A+T L++ +EQNP ASYYNV +L+YQ S G QS PL L+ +W+C A+ T + V+Y Y
Sbjct: 716 ALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYR 775
Query: 661 PEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSL 720
P A P+ L+N+Q+++PV VTN++ P A WN E+ + W+L +SE GGSG L
Sbjct: 776 PGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEA---GGSGRL 832
Query: 721 RAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGRYLADC 777
A ++ GPS P+ +A QF SEG+TLSGVD ELVG+GYR+SL+K+RFATG YL C
Sbjct: 833 SASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFATGMYLVSC 889
>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
Length = 891
Score = 674 bits (1740), Expect = 0.0
Identities = 385/890 (43%), Positives = 537/890 (60%), Gaps = 130/890 (14%)
Query: 3 MAYFVENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKSASN 62
M+YF E+FWGEKN GF+VLYH++K G ISTKELADF+RERATIEE YS++M KL+K ASN
Sbjct: 1 MSYFGEHFWGEKNHGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASN 60
Query: 63 YSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGT 122
+ +GTFAP+W+VF+ S++KLA CHL+L RKLQ+LIK+V +YGEEQ+K+HKK KEEV T
Sbjct: 61 GTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVST 120
Query: 123 LEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVE 182
L+AVQ + ++Q L KS+ENY +C++QERL++E +Q+E++KA K+KKA ++ + VE
Sbjct: 121 LDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKKAAESLRRSVE 180
Query: 183 KYALAKADFEQKMTETA---------------------------------QVHEEFINNM 209
KY A+ADFEQKM ++A QVHEEF N+
Sbjct: 181 KYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIGQVHEEFKQNI 240
Query: 210 ANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKP-RKRKTFALPGIIKKEKD 268
N +VE L++KFAESKGTG+E+PG ++FE A+ E +K R K F LPG+ ++E++
Sbjct: 241 ENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFRLPGLSRRERE 300
Query: 269 AE---SVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIE 325
E +V+ + DS P+VDEEG++++P+ QN T E +SSSDSD +DEEP+K+ +
Sbjct: 301 PEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVH 360
Query: 326 IKPMHPN-NSHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTK-SKPSAPP 383
IKP + A+ +L+ + G++ L P M R+ S + K +P + P
Sbjct: 361 IKPAPARAPACSPEAAAAQLRATAGSLILPPGPGG----TMKRHSSRDAAGKPQRPRSAP 416
Query: 384 NEKGTSDLLAWDP-----LFGPSLDS---------SSSSSLTSSSS-------------- 415
++ L + LFGP L+S SSS TSS S
Sbjct: 417 RTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSSSSPENVEDSG 476
Query: 416 -----------------ARPTTPLSVGT----------IVPPPRPASRPKLTSG------ 442
RP TP S + I PP P S L S
Sbjct: 477 LDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGL 536
Query: 443 -KLSGINEIPRPFSPPVTSNTSPPP--------AAPLARAE-------SSSSISSSASLS 486
L+G + +P P P + PP + PL R+ S S + SSA+ +
Sbjct: 537 EALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAAST 596
Query: 487 AANTPTV------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDM 540
A P+ GVSRGPSPV LG+QD LP+A A TE V+AYF+G P+ C+ ++TG++
Sbjct: 597 ALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPS-CLARVTGEL 655
Query: 541 TMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQ 600
TM+FP+GI++VF+ P P VL FR+ + + +E PNA L+FSDPSQ D TKDFW+NM
Sbjct: 656 TMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMA 715
Query: 601 AVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYN 660
A+T L++ +EQNP ASYYNV +L+YQ S G QS PL L+ +W+C A+ T + V+Y Y
Sbjct: 716 ALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYR 775
Query: 661 PEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSL 720
P A P+ L+N+Q+++PV VTN++ P A WN E+ + W+L +SE GGSG L
Sbjct: 776 PGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEA---GGSGRL 832
Query: 721 RAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFAT 770
A ++ GPS P+ +A QF SEG+TLSGVD ELVG+GYR+SL+K+RFAT
Sbjct: 833 SASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT 882
>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
Length = 839
Score = 604 bits (1558), Expect = e-173
Identities = 352/847 (41%), Positives = 496/847 (58%), Gaps = 130/847 (15%)
Query: 53 MTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSH 112
M KL+K ASN + +GTFAP+W+VF+ S++KLA CHL+L RKLQ+LIK+V +YGEEQ+K+H
Sbjct: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTH 60
Query: 113 KKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
KK KEEV TL+AVQ + ++Q L KS+ENY +C++QERL++E +Q+E++KA K+KK
Sbjct: 61 KKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQERLRRESTSQKEMDKAETKTKK 120
Query: 173 ATDTYKLYVEKYALAKADFEQKMTETA--------------------------------- 199
A ++ + VEKY A+ADFEQKM ++A
Sbjct: 121 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 180
Query: 200 QVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKP-RKRKTFA 258
QVHEEF N+ N +VE L++KFAESKGTG+E+PG ++FE A+ E +K R K F
Sbjct: 181 QVHEEFKQNIENVSVEMLLRKFAESKGTGREKPGPLDFEAYSAAALQEAMKRLRGAKAFR 240
Query: 259 LPGIIKKEKDAE---SVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSE 315
LPG+ ++E++ E +V+ + DS P+VDEEG++++P+ QN T E +SSSDSD +
Sbjct: 241 LPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFD 300
Query: 316 DEEPKKYRIEIKPMHPNN-SHHTMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEEL 374
DEEP+K+ + IKP + A+ +L+ + G++ L P M R+ S +
Sbjct: 301 DEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGG----TMKRHSSRDAA 356
Query: 375 TK-SKPSAPPNEKGTSDLLAWDP-----LFGPSLDS---------SSSSSLTSSSSA--- 416
K +P + P ++ L + LFGP L+S SSS TSS S
Sbjct: 357 GKPQRPRSAPRTSSCAERLQSEEQVSKNLFGPPLESAFDHEDFTGSSSLGFTSSPSPFSS 416
Query: 417 ----------------------------RPTTPLSVGT----------IVPPPRPASRPK 438
RP TP S + I PP P S
Sbjct: 417 SSPENVEDSGLDSPSHAAPGPSPDSWVPRPGTPQSPPSCRAPPPEARGIRAPPLPDSPQP 476
Query: 439 LTSGK-------LSGINEIPRPFSPPVTSNTSPPP--------AAPLARAE-------SS 476
L S L+G + +P P P + PP + PL R+ S
Sbjct: 477 LASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSP 536
Query: 477 SSISSSASLSAANTPTV------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPT 530
S + SSA+ +A P+ GVSRGPSPV LG+QD LP+A A TE V+AYF+G P+
Sbjct: 537 SPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRGHSPS 596
Query: 531 KCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDS 590
C+ ++TG++TM+FP+GI++VF+ P P VL FR+ + + +E PNA L+FSDPSQ D
Sbjct: 597 -CLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDP 655
Query: 591 NTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSAST 650
TKDFW+NM A+T L++ +EQNP ASYYNV +L+YQ S G QS PL L+ +W+C A+
Sbjct: 656 ETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATL 715
Query: 651 TDLRVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISE 710
T + V+Y Y P A P+ L+N+Q+++PV VTN++ P A WN E+ + W+L +SE
Sbjct: 716 TQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSE 775
Query: 711 KSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFAT 770
GGSG L A ++ GPS P+ +A QF SEG+TLSGVD ELVG+GYR+SL+K+RFAT
Sbjct: 776 A---GGSGRLSASWEPLSGPSTPSPVAAQFTSEGTTLSGVDLELVGSGYRMSLVKRRFAT 832
Query: 771 GRYLADC 777
G YL C
Sbjct: 833 GMYLVSC 839
>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
1 [Homo sapiens]
Length = 828
Score = 480 bits (1235), Expect = e-135
Identities = 251/424 (59%), Positives = 304/424 (71%), Gaps = 29/424 (6%)
Query: 378 KPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPL----SVGTIVPPPRP 433
+ + PP T + P GP ++ +SS ARP TPL S PPPRP
Sbjct: 408 RATPPPPPPPTYRTVVSSP--GPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRP 465
Query: 434 ASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTV 493
SRPKL GK G+ ++ RPFSPP+ S+ SPPP APLARAES+SSISS+ SLSAA TPTV
Sbjct: 466 PSRPKLPPGK-PGVGDVSRPFSPPIHSS-SPPPIAPLARAESTSSISSTNSLSAATTPTV 523
Query: 494 --------------------GVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCI 533
G SRGPSP+++G QDTLPVA A TE+VNAYFKGADP+KCI
Sbjct: 524 ENEQPSLVWFDRGKFYLTFEGSSRGPSPLTMGAQDTLPVAAAFTETVNAYFKGADPSKCI 583
Query: 534 VKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTK 593
VKITG+M +SFP+GI + F +NP+PA L FRV N SRLE +LPN QL+ D +Q D+NTK
Sbjct: 584 VKITGEMVLSFPAGITRHFANNPSPAALTFRVINFSRLEHVLPNPQLLCCDNTQNDANTK 643
Query: 594 DFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDL 653
+FW+NM + +LKK+SEQ P A+YYNVD+LKYQVS+ GIQSTPLNLA W+C S+TDL
Sbjct: 644 EFWVNMPNLMTHLKKVSEQKPQATYYNVDMLKYQVSAQGIQSTPLNLAVNWRCEPSSTDL 703
Query: 654 RVDYKYNPEAMVAPSVLSNIQVVVPVDGGVTNMQS-LPPAIWNAEQMKAFWKLSSISEKS 712
R+DYKYN +AM L+N+Q +VP+DGGVT +Q+ LPPA+WNAEQ + WK+ IS+KS
Sbjct: 704 RIDYKYNTDAMTTAVALNNVQFLVPIDGGVTKLQAVLPPAVWNAEQQRILWKIPDISQKS 763
Query: 713 ENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFATGR 772
ENGG GSL A+F LSEGPSKP+ L VQF SEGSTLSG D ELVG GYR SLIKKRFA G+
Sbjct: 764 ENGGVGSLLARFQLSEGPSKPSPLVVQFTSEGSTLSGCDIELVGAGYRFSLIKKRFAAGK 823
Query: 773 YLAD 776
YLAD
Sbjct: 824 YLAD 827
Score = 128 bits (321), Expect = 2e-29
Identities = 113/360 (31%), Positives = 150/360 (41%), Gaps = 108/360 (30%)
Query: 246 VEGIKPRKRKTFALPGIIKKEKDAESVECPDADSL------------------------- 280
+EG+K R RK F GI KKEKD +S PD D +
Sbjct: 2 MEGLKKRTRKAF---GIRKKEKDTDSTGSPDRDGIQPSPHEPPYNSKAECAREGGKKVSK 58
Query: 281 ------------------NIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKY 322
N P++DEEGYSI+PE TK HFYSSS+S+ E+E KK+
Sbjct: 59 KSNGAPNGFYAEIDWERYNSPELDEEGYSIRPE-EPGSTKGKHFYSSSESEEEEESHKKF 117
Query: 323 RIEIKPMHPNNSHHTMASLDELKVSIGNITLSPA----ISRHSPVQMNRNLSNEELTKSK 378
I+IKP+ + A++DELK SIGNI LSP+ R SP + RNLS+EE+ + +
Sbjct: 118 NIKIKPLQSKDILKNAATVDELKASIGNIALSPSPVRKSPRRSPGAIKRNLSSEEVARPR 177
Query: 379 PSAPPNE----KGTSDLLAWDPLFGPSLDSSSSSSLT------------------SSSSA 416
S P E K D A PLFGP L+S+ T S S
Sbjct: 178 RSTPTPELISKKPPDDTTALAPLFGPPLESAFDEQKTEVLLDQPEIWGSGQPINPSMESP 237
Query: 417 RPTTPLSVGTIVP-PPR--PASRPK----LTSG-------------KLSGINEIPRPFSP 456
+ T P GT P PP+ PA+ P+ LT G KL IN++ F P
Sbjct: 238 KLTRPFPTGTPPPLPPKNVPATPPRTGSPLTIGPGNDQSATEVKIEKLPSINDLDSIFGP 297
Query: 457 PVT---------------SNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSP 501
++ S+TSP P + + A++P G P P
Sbjct: 298 VLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGPPGP 357
>gi|165905601 proline-serine-threonine phosphatase interacting
protein 2 [Homo sapiens]
Length = 334
Score = 81.3 bits (199), Expect = 3e-15
Identities = 53/194 (27%), Positives = 97/194 (50%), Gaps = 10/194 (5%)
Query: 1 MVMAYFVENFWGE---KNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
M + F NFW G+D + ++ +G+ + KE DF++ERA IEE Y + + L+
Sbjct: 1 MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLS 60
Query: 58 -KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTK 116
K S++ T +VFK + +A CH+ L + L+E ++++++ E+Q KKT
Sbjct: 61 RKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKT- 119
Query: 117 EEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDT 176
E + + +++Q + +K+NY KC +++ + E A R K ++
Sbjct: 120 ELIMDAIHKQKSLQ--FKKTMDAKKNYEQKCRDKD--EAEQAVSRSANLVNPKQQEKL-F 174
Query: 177 YKLYVEKYALAKAD 190
KL K A+ +D
Sbjct: 175 VKLATSKTAVEDSD 188
>gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
Length = 416
Score = 80.9 bits (198), Expect = 4e-15
Identities = 82/407 (20%), Positives = 168/407 (41%), Gaps = 79/407 (19%)
Query: 1 MVMAYFVENFWGEK---NSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
M F + FW ++G++VL + G+ K++ + +R+RA EE Y + + ++A
Sbjct: 2 MPQLQFKDAFWCRDFTAHTGYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIA 61
Query: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKE 117
+ A +++ + +D K E + + H+ L L+E ++ ++++ E Q + KK +
Sbjct: 62 RKAGGQTEINSLRASFDSLKQQMENVGSSHIQLALTLREELRSLEEFRERQKEQRKKYE- 120
Query: 118 EVAGTLEAVQTIQ-SITQALQKSKENYNAKC-----VEQ--ERLKKEGATQREIEKAAVK 169
++ VQ + S+ + +SK+ Y KC EQ ER+ G Q+++EK+ K
Sbjct: 121 ---AVMDRVQKSKLSLYKKAMESKKTYEQKCRDADDAEQAFERISANG-HQKQVEKSQNK 176
Query: 170 SKKATDT-------YKLYVEKYALAKADFEQKMTETA----------------------- 199
+++ D+ Y+ + + +A++EQ+ T
Sbjct: 177 ARQCKDSATEAERVYRQSIAQLEKVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSN 236
Query: 200 ----------QVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFE-----ECDTAS 244
+++EE + ++++ I F ++K TG E P + ++ E +
Sbjct: 237 QLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLT 296
Query: 245 AVEGIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKEN 304
+ GI+P G++ P SL E + PE N+
Sbjct: 297 SSPGIQPSCGMIKRFSGLLHGS--------PKTTSLAASAASTETLTPTPERNEG----- 343
Query: 305 HFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNI 351
Y++ P E + ++ +T + DEL +S G+I
Sbjct: 344 -VYTAIAVQEIQGNPASPAQEYRALY----DYTAQNPDELDLSAGDI 385
>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
Length = 412
Score = 77.4 bits (189), Expect = 5e-14
Identities = 55/210 (26%), Positives = 102/210 (48%), Gaps = 15/210 (7%)
Query: 6 FVENFWGEKN--------SGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
+ + FW +K +GF++L G+ KE+++F+RER IEE Y++++ KL+
Sbjct: 136 YCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLS 195
Query: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKL-QELIKEVQKYGEEQVKSHKKTK 116
+++ + G+ W K S A HL KL E+ K + + E K KK
Sbjct: 196 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 255
Query: 117 EEVAGTLEAV----QTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
+A + + +++ +AL + + + K +Q +K T+ +I+KA KS +
Sbjct: 256 HHIADLRKQLASRYASVEKARKALTERQRDLEMK-TQQLEIKLSNKTEEDIKKARRKSTQ 314
Query: 173 ATDTYKLYVEKYALAKAD-FEQKMTETAQV 201
A D V+ Y A++ FE+ +T T ++
Sbjct: 315 AGDDLMRCVDLYNQAQSKWFEEMVTTTLEL 344
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 77.4 bits (189), Expect = 5e-14
Identities = 55/210 (26%), Positives = 102/210 (48%), Gaps = 15/210 (7%)
Query: 6 FVENFWGEKN--------SGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
+ + FW +K +GF++L G+ KE+++F+RER IEE Y++++ KL+
Sbjct: 200 YCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLS 259
Query: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKL-QELIKEVQKYGEEQVKSHKKTK 116
+++ + G+ W K S A HL KL E+ K + + E K KK
Sbjct: 260 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 319
Query: 117 EEVAGTLEAV----QTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
+A + + +++ +AL + + + K +Q +K T+ +I+KA KS +
Sbjct: 320 HHIADLRKQLASRYASVEKARKALTERQRDLEMK-TQQLEIKLSNKTEEDIKKARRKSTQ 378
Query: 173 ATDTYKLYVEKYALAKAD-FEQKMTETAQV 201
A D V+ Y A++ FE+ +T T ++
Sbjct: 379 AGDDLMRCVDLYNQAQSKWFEEMVTTTLEL 408
>gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]
Length = 416
Score = 77.4 bits (189), Expect = 5e-14
Identities = 55/210 (26%), Positives = 102/210 (48%), Gaps = 15/210 (7%)
Query: 6 FVENFWGEKN--------SGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
+ + FW +K +GF++L G+ KE+++F+RER IEE Y++++ KL+
Sbjct: 140 YCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLS 199
Query: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKL-QELIKEVQKYGEEQVKSHKKTK 116
+++ + G+ W K S A HL KL E+ K + + E K KK
Sbjct: 200 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 259
Query: 117 EEVAGTLEAV----QTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
+A + + +++ +AL + + + K +Q +K T+ +I+KA KS +
Sbjct: 260 HHIADLRKQLASRYASVEKARKALTERQRDLEMK-TQQLEIKLSNKTEEDIKKARRKSTQ 318
Query: 173 ATDTYKLYVEKYALAKAD-FEQKMTETAQV 201
A D V+ Y A++ FE+ +T T ++
Sbjct: 319 AGDDLMRCVDLYNQAQSKWFEEMVTTTLEL 348
>gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
Length = 336
Score = 77.4 bits (189), Expect = 5e-14
Identities = 55/210 (26%), Positives = 102/210 (48%), Gaps = 15/210 (7%)
Query: 6 FVENFWGEKN--------SGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
+ + FW +K +GF++L G+ KE+++F+RER IEE Y++++ KL+
Sbjct: 60 YCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLS 119
Query: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKL-QELIKEVQKYGEEQVKSHKKTK 116
+++ + G+ W K S A HL KL E+ K + + E K KK
Sbjct: 120 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 179
Query: 117 EEVAGTLEAV----QTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
+A + + +++ +AL + + + K +Q +K T+ +I+KA KS +
Sbjct: 180 HHIADLRKQLASRYASVEKARKALTERQRDLEMK-TQQLEIKLSNKTEEDIKKARRKSTQ 238
Query: 173 ATDTYKLYVEKYALAKAD-FEQKMTETAQV 201
A D V+ Y A++ FE+ +T T ++
Sbjct: 239 AGDDLMRCVDLYNQAQSKWFEEMVTTTLEL 268
>gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
Length = 486
Score = 59.7 bits (143), Expect = 1e-08
Identities = 60/254 (23%), Positives = 113/254 (44%), Gaps = 16/254 (6%)
Query: 8 ENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKS----ASNY 63
++FW N + + G +L + + ERA IE+AY++ +T+ A+
Sbjct: 16 DSFWEVGN--YKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKG 73
Query: 64 SQLGTFAPVWDVFKTSTEKLANCHLDLVRKLQ----ELIKEVQK--YGEEQVKSHKKTKE 117
Q GT W F + E+++ HL++ L E IK QK + ++ + K+TKE
Sbjct: 74 PQYGTVEKAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKE 133
Query: 118 EVAGTLEAVQTIQSITQALQKSKENYNAKCVEQE-RLKKEGATQREIEKAAVKSKKATDT 176
G +A + + ++ +K+ ++A C E++ + +E ++ + + KK D
Sbjct: 134 AEDGFRKAQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDK 193
Query: 177 YKLYVEKYALAKADFEQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIE 236
+ + K +E+ + E Q +++ NM V Q+F E K R L+E
Sbjct: 194 IEKCKQDVLKTKEKYEKSLKELDQGTPQYMENMEQ--VFEQCQQF-EEKRLRFFREVLLE 250
Query: 237 FEECDTASAVEGIK 250
++ S V G K
Sbjct: 251 VQKHLDLSNVAGYK 264
>gi|24308229 protein kinase C and casein kinase substrate in neurons
1 [Homo sapiens]
Length = 444
Score = 55.1 bits (131), Expect = 2e-07
Identities = 51/229 (22%), Positives = 98/229 (42%), Gaps = 15/229 (6%)
Query: 8 ENFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAKS----ASNY 63
++FW N + + G +L + V+ERA IE+AY + +T AK
Sbjct: 17 DSFWEVGN--YKRTVKRIDDGHRLCNDLMNCVQERAKIEKAYGQQLTDWAKRWRQLIEKG 74
Query: 64 SQLGTFAPVWDVFKTSTEKLANCHLDLVRKL----QELIKEVQK--YGEEQVKSHKKTKE 117
Q G+ W T +K++ H ++ L E +K QK Y ++ + K+TKE
Sbjct: 75 PQYGSLERAWGAIMTEADKVSELHQEVKNNLLNEDLEKVKNWQKDAYHKQIMGGFKETKE 134
Query: 118 EVAGTLEAVQTIQSITQALQKSKENYNAKCVEQE-RLKKEGATQREIEKAAVKSKKATDT 176
G +A + + L+ +K+ Y+ C E++ + +E ++ E + KK D
Sbjct: 135 AEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQKKLQDK 194
Query: 177 YKLYVEKYALAKADFEQKMTETAQVHEEFINNMANTTVESLIQKFAESK 225
+ + +E+ + + + +++ NM V Q+F E +
Sbjct: 195 VDKCKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQ--VFEQCQQFEEKR 241
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 51.6 bits (122), Expect = 3e-06
Identities = 75/373 (20%), Positives = 144/373 (38%), Gaps = 29/373 (7%)
Query: 26 KHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGT--------FAPVWDVFK 77
K QI ++ A+ E +++ + ++ KL + ++ L + A + F+
Sbjct: 805 KELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFR 864
Query: 78 TSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQ-SITQA- 135
E+ + KL+ I E+ K + K +E+ V+ +Q +T+A
Sbjct: 865 EKDEREEQL-IKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKAN 923
Query: 136 -----LQKSKENYNAKCVE--QERLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALAK 188
LQKS E+ K + QE KK ++E+E+ +K +T ++ K
Sbjct: 924 ENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQEL---K 980
Query: 189 ADFEQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLI-EFEECDTASAVE 247
A +E+ +ET HEE + N+ T L+ + KG +E GL+ E EE +
Sbjct: 981 ARYERATSETKTKHEEILQNLQKT----LLDTEDKLKGAREENSGLLQELEELRKQADKA 1036
Query: 248 GIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFY 307
+ + KEK D N + E ++K +N + N
Sbjct: 1037 KAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTN-AKLQNELDTLKENNLKNVEELNKSK 1095
Query: 308 SSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNI--TLSPAISRHSPVQM 365
+++ E + IE +++L E V + ++ H ++
Sbjct: 1096 ELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEE 1155
Query: 366 NRNLSNEELTKSK 378
R++ N +L + K
Sbjct: 1156 ERSVLNNQLLEMK 1168
Score = 36.6 bits (83), Expect = 0.091
Identities = 62/313 (19%), Positives = 123/313 (39%), Gaps = 46/313 (14%)
Query: 48 AYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRK------LQELIKEV 101
A + + K + SAS+ S + + A + T L RK LQE +KE
Sbjct: 301 ATTSASLKRSPSASSLSSMSSVASSVSSRPSRTGLLTETSSRYARKISGTTALQEALKEK 360
Query: 102 QKYGEEQVKSHKKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQE------RLKK 155
Q++ E+ + + EVA +A + I Q L +++ ++ +E E R
Sbjct: 361 QQHIEQLLAERDLERAEVA---KATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMV 417
Query: 156 EGATQREIE--KAAVKSKKATDTYKLYVEKYALAKADFEQKMTETAQVHEEFINNMANTT 213
E A + ++E + K+ + + VE+ ++ K D E +A +
Sbjct: 418 EAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE----------------VATVS 461
Query: 214 VESLIQKFAESKGTGKERPGLIEFEECDTASAVEGIKPRKRKTFALPGIIKKEKDAESVE 273
+S I + + + E + +E KP +L + + E +E
Sbjct: 462 EKSRIMELEKDLALRVQ-------EVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLE 514
Query: 274 CPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKKYRIEIKPMHPNN 333
D +E + + ET+Q + K Y++++ S++ E K ++E H N
Sbjct: 515 VTRTDHQREITSLKEHFGAREETHQKEIKA--LYTATEKLSKENESLKSKLE----HANK 568
Query: 334 SHHTMASLDELKV 346
+ + +L + K+
Sbjct: 569 ENSDVIALWKSKL 581
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 51.6 bits (122), Expect = 3e-06
Identities = 75/373 (20%), Positives = 144/373 (38%), Gaps = 29/373 (7%)
Query: 26 KHGQISTKELADFVRERATIEEAYSRSMTKLAKSASNYSQLGT--------FAPVWDVFK 77
K QI ++ A+ E +++ + ++ KL + ++ L + A + F+
Sbjct: 840 KELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFR 899
Query: 78 TSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQ-SITQA- 135
E+ + KL+ I E+ K + K +E+ V+ +Q +T+A
Sbjct: 900 EKDEREEQL-IKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKAN 958
Query: 136 -----LQKSKENYNAKCVE--QERLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALAK 188
LQKS E+ K + QE KK ++E+E+ +K +T ++ K
Sbjct: 959 ENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQEL---K 1015
Query: 189 ADFEQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLI-EFEECDTASAVE 247
A +E+ +ET HEE + N+ T L+ + KG +E GL+ E EE +
Sbjct: 1016 ARYERATSETKTKHEEILQNLQKT----LLDTEDKLKGAREENSGLLQELEELRKQADKA 1071
Query: 248 GIKPRKRKTFALPGIIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFY 307
+ + KEK D N + E ++K +N + N
Sbjct: 1072 KAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTN-AKLQNELDTLKENNLKNVEELNKSK 1130
Query: 308 SSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNI--TLSPAISRHSPVQM 365
+++ E + IE +++L E V + ++ H ++
Sbjct: 1131 ELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEE 1190
Query: 366 NRNLSNEELTKSK 378
R++ N +L + K
Sbjct: 1191 ERSVLNNQLLEMK 1203
Score = 45.8 bits (107), Expect = 2e-04
Identities = 69/325 (21%), Positives = 134/325 (41%), Gaps = 35/325 (10%)
Query: 48 AYSRSMTKLAKSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRK------LQELIKEV 101
A + + K + SAS+ S + + A + T L RK LQE +KE
Sbjct: 301 ATTSASLKRSPSASSLSSMSSVASSVSSRPSRTGLLTETSSRYARKISGTTALQEALKEK 360
Query: 102 QKYGEEQVKSHKKTKEEVAGTLEAVQTIQSITQALQKSKENYNAKCVEQE------RLKK 155
Q++ E+ + + EVA +A + I Q L +++ ++ +E E R
Sbjct: 361 QQHIEQLLAERDLERAEVA---KATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMV 417
Query: 156 EGATQREIE--KAAVKSKKATDTYKLYVEKYALAKADFE-QKMTETAQVHEEFINNMANT 212
E A + ++E + K+ + + VE+ ++ K D E Q E A++ E + +
Sbjct: 418 EAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFEK 477
Query: 213 TVESLIQKFAESK--GTGKERPGLIEFEE---------CDTASAVEGIKPRKRKTFALPG 261
T +Q+ E T E+ ++E E+ + +E KP +L
Sbjct: 478 TKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSL 537
Query: 262 IIKKEKDAESVECPDADSLNIPDVDEEGYSIKPETNQNDTKENHFYSSSDSDSEDEEPKK 321
+ + E +E D +E + + ET+Q + K Y++++ S++ E K
Sbjct: 538 LQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKA--LYTATEKLSKENESLK 595
Query: 322 YRIEIKPMHPNNSHHTMASLDELKV 346
++E H N + + +L + K+
Sbjct: 596 SKLE----HANKENSDVIALWKSKL 616
>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 50.1 bits (118), Expect = 8e-06
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 9/112 (8%)
Query: 396 PLFGPSLDSSSSSSLTSSSSARPT-TPLSVGTIVPPPRP----ASRPKLTSGKLSGINEI 450
P P L SS+ +LT SS+ PT TP S T+ P P +SRP LT +
Sbjct: 162 PSSRPILTRSSTPTLTPSST--PTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPS 219
Query: 451 PRPFSPPVTSNTSPPPAAPLARAESSSSI--SSSASLSAANTPTVGVSRGPS 500
RP P ++ T P + P+ S+ ++ SS+ +L+ +NTPT+ S P+
Sbjct: 220 SRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPT 271
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 17/116 (14%)
Query: 400 PSLDSSSSSSLTSSSSARPT-TPLSVGTIVPPPRP------------ASRPKLTSGKLSG 446
P+L SS+ +LT SS+ PT TP S T+ P RP +SRP LT
Sbjct: 174 PTLTPSSTPTLTPSST--PTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPT 231
Query: 447 INEIPRPFSPPVTSNTSPPPAAPLARAESSSSI--SSSASLSAANTPTVGVSRGPS 500
+ RP ++ T P + P ++ ++ S++ +L+ +NTPT+ S P+
Sbjct: 232 LTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPT 287
Score = 41.6 bits (96), Expect = 0.003
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 5/110 (4%)
Query: 396 PLFGPSLDSSSSSSLTSSSS---ARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPR 452
P P L SS+ +LT SS R +TP + P P+S P LT + R
Sbjct: 146 PSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSR 205
Query: 453 PFSPPVTSNTSPPPAAPLARAESSSSI--SSSASLSAANTPTVGVSRGPS 500
P ++ T P + P+ S+ ++ SS L+ ++TPT+ S P+
Sbjct: 206 PILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPT 255
Score = 41.2 bits (95), Expect = 0.004
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 14/122 (11%)
Query: 379 PSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPT-TPLSVGTIVPPPRPASRP 437
PS+PP S+ P P+L S++ +LT SS+ PT TP S T+ P +SRP
Sbjct: 98 PSSPPTLT-PSNTPTLTPSNTPTLTPSNTPTLTPSST--PTLTPSSTPTLTP----SSRP 150
Query: 438 KLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSR 497
LT + P S P+ + +S P P + + + SS+ +L+ ++TPT+ S
Sbjct: 151 ILTRSSTPTLT----PSSRPILTRSSTPTLTP--SSTPTLTPSSTPTLTPSSTPTLTPSS 204
Query: 498 GP 499
P
Sbjct: 205 RP 206
Score = 40.8 bits (94), Expect = 0.005
Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 400 PSLDSSSSSSLTSSSSARPT---TPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSP 456
P+L SS +LT S++ T TP + P P+S P LT + RP
Sbjct: 94 PTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILT 153
Query: 457 PVTSNTSPPPAAPLARAESSSSI--SSSASLSAANTPTVGVSRGPS 500
++ T P + P+ S+ ++ SS+ +L+ ++TPT+ S P+
Sbjct: 154 RSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 199
Score = 40.4 bits (93), Expect = 0.006
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 3/108 (2%)
Query: 396 PLFGPSLDSSSSSSLTSSSS---ARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPR 452
P P+L SS+ +LT SS R +TP + P P++ P LT +
Sbjct: 12 PSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSST 71
Query: 453 PFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPS 500
P P ++ T P + + + SS +L+ +NTPT+ S P+
Sbjct: 72 PTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPT 119
Score = 40.4 bits (93), Expect = 0.006
Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 14/161 (8%)
Query: 355 PAISRHSPVQMNRNLSNEELTKSK-PSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSS 413
P ++R S + + S LT+S P+ P+ T P P+L SS+ +LT S
Sbjct: 150 PILTRSSTPTLTPS-SRPILTRSSTPTLTPSSTPTLT-----PSSTPTLTPSSTPTLTPS 203
Query: 414 SS---ARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPL 470
S R +TP + P P+S P LT + P P ++ T P P
Sbjct: 204 SRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPT 263
Query: 471 ARAESSSSI--SSSASLSAANTPTVGVSRGP--SPVSLGNQ 507
++ ++ S++ +L+ ++TPT+ S P +P SL +Q
Sbjct: 264 LTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSLWHQ 304
Score = 37.0 bits (84), Expect = 0.070
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 17/108 (15%)
Query: 396 PLFGPSLDSSSSSSLTSSSSARPT---TPLSVGTIVPPPRPASRPKLTSGKLSGINEIPR 452
P P+L S++ +LT S++ T TP + P P+S P LT
Sbjct: 98 PSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLT------------ 145
Query: 453 PFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPS 500
P S P+ + +S P P +R + SS+ +L+ ++TPT+ S P+
Sbjct: 146 PSSRPILTRSSTPTLTPSSRPILTR--SSTPTLTPSSTPTLTPSSTPT 191
Score = 33.1 bits (74), Expect = 1.0
Identities = 37/144 (25%), Positives = 60/144 (41%), Gaps = 19/144 (13%)
Query: 420 TPLSVGTIVP--PPR--PASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAES 475
TP + T+ P PP P+S P LT P S P+ + +S P P +
Sbjct: 3 TPSNTPTLTPSSPPTLTPSSTPTLT------------PSSQPILTRSSTPTLTP--SSPP 48
Query: 476 SSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVK 535
+ + S++ +L+ +NTPT+ S P+ ++ + TL LT S + P
Sbjct: 49 TLTPSNTPTLTPSNTPTLTPSSTPT-LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPS 107
Query: 536 ITGDMTMSFPSGIIKVFTSNPTPA 559
T +T S + T TP+
Sbjct: 108 NTPTLTPSNTPTLTPSNTPTLTPS 131
>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 50.1 bits (118), Expect = 8e-06
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 9/112 (8%)
Query: 396 PLFGPSLDSSSSSSLTSSSSARPT-TPLSVGTIVPPPRP----ASRPKLTSGKLSGINEI 450
P P L SS+ +LT SS+ PT TP S T+ P P +SRP LT +
Sbjct: 162 PSSRPILTRSSTPTLTPSST--PTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPS 219
Query: 451 PRPFSPPVTSNTSPPPAAPLARAESSSSI--SSSASLSAANTPTVGVSRGPS 500
RP P ++ T P + P+ S+ ++ SS+ +L+ +NTPT+ S P+
Sbjct: 220 SRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPT 271
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 17/116 (14%)
Query: 400 PSLDSSSSSSLTSSSSARPT-TPLSVGTIVPPPRP------------ASRPKLTSGKLSG 446
P+L SS+ +LT SS+ PT TP S T+ P RP +SRP LT
Sbjct: 174 PTLTPSSTPTLTPSST--PTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPT 231
Query: 447 INEIPRPFSPPVTSNTSPPPAAPLARAESSSSI--SSSASLSAANTPTVGVSRGPS 500
+ RP ++ T P + P ++ ++ S++ +L+ +NTPT+ S P+
Sbjct: 232 LTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPT 287
Score = 41.6 bits (96), Expect = 0.003
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 5/110 (4%)
Query: 396 PLFGPSLDSSSSSSLTSSSS---ARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPR 452
P P L SS+ +LT SS R +TP + P P+S P LT + R
Sbjct: 146 PSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSR 205
Query: 453 PFSPPVTSNTSPPPAAPLARAESSSSI--SSSASLSAANTPTVGVSRGPS 500
P ++ T P + P+ S+ ++ SS L+ ++TPT+ S P+
Sbjct: 206 PILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPT 255
Score = 41.2 bits (95), Expect = 0.004
Identities = 39/122 (31%), Positives = 61/122 (50%), Gaps = 14/122 (11%)
Query: 379 PSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPT-TPLSVGTIVPPPRPASRP 437
PS+PP S+ P P+L S++ +LT SS+ PT TP S T+ P +SRP
Sbjct: 98 PSSPPTLT-PSNTPTLTPSNTPTLTPSNTPTLTPSST--PTLTPSSTPTLTP----SSRP 150
Query: 438 KLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSR 497
LT + P S P+ + +S P P + + + SS+ +L+ ++TPT+ S
Sbjct: 151 ILTRSSTPTLT----PSSRPILTRSSTPTLTP--SSTPTLTPSSTPTLTPSSTPTLTPSS 204
Query: 498 GP 499
P
Sbjct: 205 RP 206
Score = 40.8 bits (94), Expect = 0.005
Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 400 PSLDSSSSSSLTSSSSARPT---TPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSP 456
P+L SS +LT S++ T TP + P P+S P LT + RP
Sbjct: 94 PTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILT 153
Query: 457 PVTSNTSPPPAAPLARAESSSSI--SSSASLSAANTPTVGVSRGPS 500
++ T P + P+ S+ ++ SS+ +L+ ++TPT+ S P+
Sbjct: 154 RSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 199
Score = 40.4 bits (93), Expect = 0.006
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 3/108 (2%)
Query: 396 PLFGPSLDSSSSSSLTSSSS---ARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPR 452
P P+L SS+ +LT SS R +TP + P P++ P LT +
Sbjct: 12 PSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSST 71
Query: 453 PFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPS 500
P P ++ T P + + + SS +L+ +NTPT+ S P+
Sbjct: 72 PTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPT 119
Score = 40.4 bits (93), Expect = 0.006
Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 14/161 (8%)
Query: 355 PAISRHSPVQMNRNLSNEELTKSK-PSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSS 413
P ++R S + + S LT+S P+ P+ T P P+L SS+ +LT S
Sbjct: 150 PILTRSSTPTLTPS-SRPILTRSSTPTLTPSSTPTLT-----PSSTPTLTPSSTPTLTPS 203
Query: 414 SS---ARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPL 470
S R +TP + P P+S P LT + P P ++ T P P
Sbjct: 204 SRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPT 263
Query: 471 ARAESSSSI--SSSASLSAANTPTVGVSRGP--SPVSLGNQ 507
++ ++ S++ +L+ ++TPT+ S P +P SL +Q
Sbjct: 264 LTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSLWHQ 304
Score = 37.0 bits (84), Expect = 0.070
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 17/108 (15%)
Query: 396 PLFGPSLDSSSSSSLTSSSSARPT---TPLSVGTIVPPPRPASRPKLTSGKLSGINEIPR 452
P P+L S++ +LT S++ T TP + P P+S P LT
Sbjct: 98 PSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLT------------ 145
Query: 453 PFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPS 500
P S P+ + +S P P +R + SS+ +L+ ++TPT+ S P+
Sbjct: 146 PSSRPILTRSSTPTLTPSSRPILTR--SSTPTLTPSSTPTLTPSSTPT 191
Score = 33.1 bits (74), Expect = 1.0
Identities = 37/144 (25%), Positives = 60/144 (41%), Gaps = 19/144 (13%)
Query: 420 TPLSVGTIVP--PPR--PASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAES 475
TP + T+ P PP P+S P LT P S P+ + +S P P +
Sbjct: 3 TPSNTPTLTPSSPPTLTPSSTPTLT------------PSSQPILTRSSTPTLTP--SSPP 48
Query: 476 SSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVK 535
+ + S++ +L+ +NTPT+ S P+ ++ + TL LT S + P
Sbjct: 49 TLTPSNTPTLTPSNTPTLTPSSTPT-LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPS 107
Query: 536 ITGDMTMSFPSGIIKVFTSNPTPA 559
T +T S + T TP+
Sbjct: 108 NTPTLTPSNTPTLTPSNTPTLTPS 131
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 49.3 bits (116), Expect = 1e-05
Identities = 45/183 (24%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Query: 337 TMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDP 396
T++S + + S TL+P +SP + + + + P APP+ + A P
Sbjct: 138 TISSRENVNTSSSVATLAPV---NSPAPQDTTAAPPTPSATTP-APPSSSAPPETTAAPP 193
Query: 397 LFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSP 456
+ + SSS ++A P TP + T PP ++ P+ T+ + P P S
Sbjct: 194 TPSATTQAPPSSSAPPETTAAPPTPPA--TTPAPPSSSAPPETTAAPPTPSATTPAPLSS 251
Query: 457 PVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVAL 516
T+ P P A SS S+ +AA PT + P S Q+T +
Sbjct: 252 SAPPETTAVPPTPSATTLDPSSASAPPETTAA-PPTPSATTPAPPSSPAPQETTAAPITT 310
Query: 517 TES 519
S
Sbjct: 311 PNS 313
Score = 35.8 bits (81), Expect = 0.16
Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 13/142 (9%)
Query: 381 APPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARP-----TTPLSVGTIVPPPRPAS 435
APP+ + A P + + SSS ++A P TTP + + PP A
Sbjct: 201 APPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAV 260
Query: 436 RPKLTSGKLSGINEIPRP---FSPPVTSNTSP-PPAAPLARAESSSSI----SSSASLSA 487
P ++ L + P +PP S T+P PP++P + +++ I SS +L+
Sbjct: 261 PPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP 320
Query: 488 ANTPTVGVSRGPSPVSLGNQDT 509
+ T + S+ Q T
Sbjct: 321 DTSETSAAPTHQTTTSVTTQTT 342
Score = 30.4 bits (67), Expect = 6.6
Identities = 27/104 (25%), Positives = 42/104 (40%), Gaps = 3/104 (2%)
Query: 400 PSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVT 459
P++ ++ T SS T SV T+ P PA + T+ + P P S
Sbjct: 127 PNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQ-DTTAAPPTPSATTPAPPSSSAP 185
Query: 460 SNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVS 503
T+ P P A ++ S S+ +AA P + P+P S
Sbjct: 186 PETTAAPPTPSATTQAPPSSSAPPETTAA--PPTPPATTPAPPS 227
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 49.3 bits (116), Expect = 1e-05
Identities = 45/183 (24%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Query: 337 TMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDP 396
T++S + + S TL+P +SP + + + + P APP+ + A P
Sbjct: 138 TISSRENVNTSSSVATLAPV---NSPAPQDTTAAPPTPSATTP-APPSSSAPPETTAAPP 193
Query: 397 LFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSP 456
+ + SSS ++A P TP + T PP ++ P+ T+ + P P S
Sbjct: 194 TPSATTQAPPSSSAPPETTAAPPTPPA--TTPAPPSSSAPPETTAAPPTPSATTPAPLSS 251
Query: 457 PVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVAL 516
T+ P P A SS S+ +AA PT + P S Q+T +
Sbjct: 252 SAPPETTAVPPTPSATTLDPSSASAPPETTAA-PPTPSATTPAPPSSPAPQETTAAPITT 310
Query: 517 TES 519
S
Sbjct: 311 PNS 313
Score = 35.8 bits (81), Expect = 0.16
Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 13/142 (9%)
Query: 381 APPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARP-----TTPLSVGTIVPPPRPAS 435
APP+ + A P + + SSS ++A P TTP + + PP A
Sbjct: 201 APPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAV 260
Query: 436 RPKLTSGKLSGINEIPRP---FSPPVTSNTSP-PPAAPLARAESSSSI----SSSASLSA 487
P ++ L + P +PP S T+P PP++P + +++ I SS +L+
Sbjct: 261 PPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP 320
Query: 488 ANTPTVGVSRGPSPVSLGNQDT 509
+ T + S+ Q T
Sbjct: 321 DTSETSAAPTHQTTTSVTTQTT 342
Score = 30.4 bits (67), Expect = 6.6
Identities = 27/104 (25%), Positives = 42/104 (40%), Gaps = 3/104 (2%)
Query: 400 PSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVT 459
P++ ++ T SS T SV T+ P PA + T+ + P P S
Sbjct: 127 PNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQ-DTTAAPPTPSATTPAPPSSSAP 185
Query: 460 SNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVS 503
T+ P P A ++ S S+ +AA P + P+P S
Sbjct: 186 PETTAAPPTPSATTQAPPSSSAPPETTAA--PPTPPATTPAPPS 227
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 49.3 bits (116), Expect = 1e-05
Identities = 45/183 (24%), Positives = 73/183 (39%), Gaps = 7/183 (3%)
Query: 337 TMASLDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDP 396
T++S + + S TL+P +SP + + + + P APP+ + A P
Sbjct: 138 TISSRENVNTSSSVATLAPV---NSPAPQDTTAAPPTPSATTP-APPSSSAPPETTAAPP 193
Query: 397 LFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSP 456
+ + SSS ++A P TP + T PP ++ P+ T+ + P P S
Sbjct: 194 TPSATTQAPPSSSAPPETTAAPPTPPA--TTPAPPSSSAPPETTAAPPTPSATTPAPLSS 251
Query: 457 PVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVAL 516
T+ P P A SS S+ +AA PT + P S Q+T +
Sbjct: 252 SAPPETTAVPPTPSATTLDPSSASAPPETTAA-PPTPSATTPAPPSSPAPQETTAAPITT 310
Query: 517 TES 519
S
Sbjct: 311 PNS 313
Score = 35.8 bits (81), Expect = 0.16
Identities = 35/142 (24%), Positives = 59/142 (41%), Gaps = 13/142 (9%)
Query: 381 APPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARP-----TTPLSVGTIVPPPRPAS 435
APP+ + A P + + SSS ++A P TTP + + PP A
Sbjct: 201 APPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAV 260
Query: 436 RPKLTSGKLSGINEIPRP---FSPPVTSNTSP-PPAAPLARAESSSSI----SSSASLSA 487
P ++ L + P +PP S T+P PP++P + +++ I SS +L+
Sbjct: 261 PPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP 320
Query: 488 ANTPTVGVSRGPSPVSLGNQDT 509
+ T + S+ Q T
Sbjct: 321 DTSETSAAPTHQTTTSVTTQTT 342
Score = 30.4 bits (67), Expect = 6.6
Identities = 27/104 (25%), Positives = 42/104 (40%), Gaps = 3/104 (2%)
Query: 400 PSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVT 459
P++ ++ T SS T SV T+ P PA + T+ + P P S
Sbjct: 127 PNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQ-DTTAAPPTPSATTPAPPSSSAP 185
Query: 460 SNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVS 503
T+ P P A ++ S S+ +AA P + P+P S
Sbjct: 186 PETTAAPPTPSATTQAPPSSSAPPETTAA--PPTPPATTPAPPS 227
>gi|24430146 nucleoporin 153kDa [Homo sapiens]
Length = 1475
Score = 48.5 bits (114), Expect = 2e-05
Identities = 65/288 (22%), Positives = 95/288 (32%), Gaps = 30/288 (10%)
Query: 297 NQNDTKENHFYS-SSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNITLSP 355
++N +K +S + S+ E E+P K T A K + S
Sbjct: 1143 DENSSKSTFSFSMTKPSEKESEQPAKATFAF-----GAQTSTTADQGAAKPVFSFLNNSS 1197
Query: 356 AISRHSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSS 415
+ S + + S P G S FG + +SS+S SL S
Sbjct: 1198 SSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQSLLFSQD 1257
Query: 416 ARPTTPLSVGTIVPP----PRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP--PPAAP 469
++ T S GT V P P +S TSG G T P P A+P
Sbjct: 1258 SKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTGPSAPSASP 1317
Query: 470 LARAESSSSISSSASLSAANTPTVG----------VSRGPSPVSLG--NQDTLPVAVALT 517
A + + S S N P G P+P + G + + P
Sbjct: 1318 AFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSSSSQPPVFGQQ 1377
Query: 518 ESVNAYFKGADPTKCIVKITGDMTMSF------PSGIIKVFTSNPTPA 559
S +A+ G P G T +F PSG+ ++ TPA
Sbjct: 1378 PSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPA 1425
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 47.4 bits (111), Expect = 5e-05
Identities = 61/252 (24%), Positives = 99/252 (39%), Gaps = 22/252 (8%)
Query: 238 EECDTASAVEGIKPRKRKTFALPGIIKKEKDAESVE---CPDADSLNIPDVDEEGYSIKP 294
EE + + E P+K KT + D +S++ D S + D+D++ S P
Sbjct: 74 EEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSP 133
Query: 295 ETNQNDTKENHFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNITLS 354
+ EN SSS P P+ P + ++ + + S
Sbjct: 134 SIYSPGSVENDSDSSSGLSQGPARP----YHPPPLFPPSPQPPDSTPRQPEASFEPHPSV 189
Query: 355 PAISRHSPVQMNRNLSNEELTKSKPSAPPNEK-----GTSDLLAWDPLFGPSLDSSSSSS 409
H+P++ + ++ P APP GT +L+ P+ GP ++SS
Sbjct: 190 TPTGYHAPMEP----PTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPM-GPKGGGAASSV 244
Query: 410 LTSSSSAR---PTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFS-PPVTSNTSPP 465
+ + PTTP+SV + P ++P T + P P + P VT N PP
Sbjct: 245 GGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPP 304
Query: 466 PA-APLARAESS 476
PA PL A +S
Sbjct: 305 PALRPLNNASAS 316
Score = 32.0 bits (71), Expect = 2.3
Identities = 33/113 (29%), Positives = 47/113 (41%), Gaps = 22/113 (19%)
Query: 401 SLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTS 460
S SSS+++ +SSSS+ + + P P S P TS LS N+ P+ P + S
Sbjct: 377 SSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS--LSVSNQPPKYTQPSLPS 434
Query: 461 ----NTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDT 509
+ PPP P R ++S+ GP P S G Q T
Sbjct: 435 QAVWSQGPPPPPPYGRLLANSN----------------AHPGPFPPSTGAQST 471
Score = 31.6 bits (70), Expect = 2.9
Identities = 29/114 (25%), Positives = 41/114 (35%), Gaps = 9/114 (7%)
Query: 396 PLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLS------GINE 449
P +G S + + +P +P S T PP + P G G
Sbjct: 637 PPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP 696
Query: 450 IPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTP--TVGVSRGPSP 501
+P P P + PPPAAP + S++ TP V +R PSP
Sbjct: 697 LP-PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 47.4 bits (111), Expect = 5e-05
Identities = 61/252 (24%), Positives = 99/252 (39%), Gaps = 22/252 (8%)
Query: 238 EECDTASAVEGIKPRKRKTFALPGIIKKEKDAESVE---CPDADSLNIPDVDEEGYSIKP 294
EE + + E P+K KT + D +S++ D S + D+D++ S P
Sbjct: 74 EEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSP 133
Query: 295 ETNQNDTKENHFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNITLS 354
+ EN SSS P P+ P + ++ + + S
Sbjct: 134 SIYSPGSVENDSDSSSGLSQGPARP----YHPPPLFPPSPQPPDSTPRQPEASFEPHPSV 189
Query: 355 PAISRHSPVQMNRNLSNEELTKSKPSAPPNEK-----GTSDLLAWDPLFGPSLDSSSSSS 409
H+P++ + ++ P APP GT +L+ P+ GP ++SS
Sbjct: 190 TPTGYHAPMEP----PTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPM-GPKGGGAASSV 244
Query: 410 LTSSSSAR---PTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFS-PPVTSNTSPP 465
+ + PTTP+SV + P ++P T + P P + P VT N PP
Sbjct: 245 GGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPP 304
Query: 466 PA-APLARAESS 476
PA PL A +S
Sbjct: 305 PALRPLNNASAS 316
Score = 32.0 bits (71), Expect = 2.3
Identities = 33/113 (29%), Positives = 47/113 (41%), Gaps = 22/113 (19%)
Query: 401 SLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTS 460
S SSS+++ +SSSS+ + + P P S P TS LS N+ P+ P + S
Sbjct: 377 SSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS--LSVSNQPPKYTQPSLPS 434
Query: 461 ----NTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDT 509
+ PPP P R ++S+ GP P S G Q T
Sbjct: 435 QAVWSQGPPPPPPYGRLLANSN----------------AHPGPFPPSTGAQST 471
Score = 31.6 bits (70), Expect = 2.9
Identities = 29/114 (25%), Positives = 41/114 (35%), Gaps = 9/114 (7%)
Query: 396 PLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLS------GINE 449
P +G S + + +P +P S T PP + P G G
Sbjct: 637 PPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP 696
Query: 450 IPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTP--TVGVSRGPSP 501
+P P P + PPPAAP + S++ TP V +R PSP
Sbjct: 697 LP-PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
>gi|19224660 protein kinase C and casein kinase substrate in neurons
3 [Homo sapiens]
Length = 424
Score = 47.4 bits (111), Expect = 5e-05
Identities = 43/212 (20%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Query: 9 NFWGEKNSGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLAK----SASNYS 64
+FW N V ++ G +L +ERA IE+AY++ + A+ +
Sbjct: 15 SFWEAGNYRRTV--QRVEDGHRLCGDLVSCFQERARIEKAYAQQLADWARKWRGTVEKGP 72
Query: 65 QLGTFAPVWDVFKTSTEKLANCHLDLVRKLQ----ELIKEVQK--YGEEQVKSHKKTKEE 118
Q GT W F T+ E+L+ HL++ KLQ E ++ Q+ + + ++++
Sbjct: 73 QYGTLEKAWHAFFTAAERLSALHLEVREKLQGQDSERVRAWQRGAFHRPVLGGFRESRAA 132
Query: 119 VAGTLEAVQTIQSITQALQKSKENYNAKCVEQERLK-KEGATQREIEKAAVKSKKATDTY 177
G +A + + ++ SK++Y+A +++ + +E + + + + +K +
Sbjct: 133 EDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTRESHAKADSAVSQEQLRKLQERV 192
Query: 178 KLYVEKYALAKADFEQKMTETAQVHEEFINNM 209
+ ++ KA +EQ + E + ++ +M
Sbjct: 193 ERCAKEAEKTKAQYEQTLAELHRYTPRYMEDM 224
>gi|111120318 NK6 transcription factor related, locus 1 [Homo
sapiens]
Length = 367
Score = 46.6 bits (109), Expect = 9e-05
Identities = 41/103 (39%), Positives = 56/103 (54%), Gaps = 9/103 (8%)
Query: 393 AWDPL-FGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPA-----SRPK-LTSGKLS 445
A+ PL GP SSSSSS +SSS + P + G + PP S P+ L++
Sbjct: 39 AYPPLPAGPP--SSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPH 96
Query: 446 GINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAA 488
GIN+I S PV S + P A+P + SSSS +S++S SAA
Sbjct: 97 GINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAA 139
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 46.6 bits (109), Expect = 9e-05
Identities = 102/430 (23%), Positives = 167/430 (38%), Gaps = 54/430 (12%)
Query: 344 LKVSIGNITLSPA-ISRHSPVQMNRNLSNEELTK---SKPSAPPNEKGTSDLLAWDPLFG 399
L VS TLS + PV + S+ T S P++PP+E GT+ L
Sbjct: 1112 LVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSE-GTTPLA------- 1163
Query: 400 PSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVT 459
S+ S++ ++S ++ TTP+ T V AS P T+ S P S P+T
Sbjct: 1164 -SMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLT 1222
Query: 460 SNTSPPPAAPLARAE----------SSSSISSSASLSAANTPTVGVSRGPSPVSLGNQ-- 507
S P P+A +E +S+ +++SA S++ T G S S S G+
Sbjct: 1223 S--MPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLL 1280
Query: 508 DTLPVAVALTESVNAYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTPA-----VLC 562
++PV+ L S A +T + P +S+PTPA
Sbjct: 1281 TSIPVSTTLVTSPEA----------STLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTS 1330
Query: 563 FRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQAVTVYLKKLS----EQNPAASY 618
+ + L I N LV S S T N VT + S + +
Sbjct: 1331 TYSEGRTPLTSIPVNTTLVASSAISILSTTP--VDNSTPVTTSTEACSSPTTSEGTSMPN 1388
Query: 619 YNVDVLKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVP 678
N ++S + +TP+ + SA+ D + EA +P+ I +
Sbjct: 1389 SNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTS 1448
Query: 679 VDG-GVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSGSLRA-KFDLSEGPSKPTTL 736
G T ++S+P + +A S++S + S + + S P++ T++
Sbjct: 1449 TPSEGKTPLKSIPVSNTPVANSEA----STLSTTPVDSNSPVVTSTAVSSSPTPAEGTSI 1504
Query: 737 AVQFLSEGST 746
A+ SEGST
Sbjct: 1505 AISTPSEGST 1514
Score = 42.7 bits (99), Expect = 0.001
Identities = 74/349 (21%), Positives = 130/349 (37%), Gaps = 38/349 (10%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNT-- 462
++SS T+ ++ PT+ LS GT P S + + ++S ++ P + P T++T
Sbjct: 2257 ATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEA 2316
Query: 463 -SPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVN 521
SPPP A +S+ +S S S NTP + + V+ TL A T +
Sbjct: 2317 SSPPPTA------EGTSMPTSTS-SEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPV 2369
Query: 522 AYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLV 581
+ A + T T ++ G S P +V + +S +
Sbjct: 2370 TTYSQAGSSPTTADDTSMPTSTYSEG------STPLTSVPVSTMPVVSSEASTHSTTPVD 2423
Query: 582 FSDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLA 641
S P + + ++ SE ++S + +TP+ +
Sbjct: 2424 TSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTT------------PLASMPVSTTPVVSS 2471
Query: 642 TYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPV---DGGVTNMQSLPPAIWNAEQ 698
S + D + EA +P+ +I VVP+ G T + S+P +
Sbjct: 2472 EAGTLSTTPVDTSTPMTTSTEASSSPTTAEDI--VVPISTASEGSTLLTSIPVSTTPVAS 2529
Query: 699 MKA-FWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGST 746
+A + + S S + + +EG S PT+ SEGST
Sbjct: 2530 PEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTST----YSEGST 2574
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/153 (27%), Positives = 67/153 (43%), Gaps = 20/153 (13%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
+SSSS T+ ++ PT+ S G+ P S + S + S ++ P S PVT++T
Sbjct: 1079 ASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTST-- 1136
Query: 465 PPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYF 524
E+SSS +++ S PT S G +P++ ++PV+ L S A
Sbjct: 1137 ---------EASSSPTTAEGTS---IPTSPPSEGTTPLA-----SMPVSTTLVVSSEANT 1179
Query: 525 KGADPTKCIVKITGDMTMSFPSGIIKVFTSNPT 557
P ++ S P +V TS PT
Sbjct: 1180 LSTTPVDSKTQVATSTEASSPPPTAEV-TSMPT 1211
Score = 40.8 bits (94), Expect = 0.005
Identities = 58/244 (23%), Positives = 90/244 (36%), Gaps = 39/244 (15%)
Query: 303 ENHFYSSSDSDSEDEEPKKYRIEIKPMHPNNSHHTMASLDELKVSIGNITLSPA------ 356
E+ S S SDS P P P + M++ E +S +S A
Sbjct: 114 ESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFE 173
Query: 357 --ISRHSPVQMNRNLSNEELTKSKPSAPP--------NEKGTSDLLAWDPLFGPSLDSSS 406
S V M+ L+ S P+ P N +G++ L S+ +S+
Sbjct: 174 AYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLT--------SMPAST 225
Query: 407 SSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVT------- 459
+S + TTP+ + T V AS T+ S N P S P+T
Sbjct: 226 MKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVM 285
Query: 460 -------SNTSPPPAAPLARAESSSSISSSASLSAANT-PTVGVSRGPSPVSLGNQDTLP 511
S S PAA +S+ SSS + + + PT + G +P++ T+P
Sbjct: 286 LVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMP 345
Query: 512 VAVA 515
VA +
Sbjct: 346 VATS 349
Score = 40.8 bits (94), Expect = 0.005
Identities = 86/368 (23%), Positives = 135/368 (36%), Gaps = 27/368 (7%)
Query: 341 LDELKVSIGNITLSPAISRHSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGP 400
L + VSI +T SP S S ++ N T+ S P E + + P
Sbjct: 808 LTSIPVSITPVT-SPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTP 866
Query: 401 --SLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPV 458
S+ S++ TS+ S TTP+ T V A TS S P S P+
Sbjct: 867 LTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPL 926
Query: 459 TS--NTSPPPAAPLARAESSSSISSS----ASLSAANTPTV--GVSRGPSPVSLGNQ--D 508
TS +++ P + AR S++ + +S S A ++PT G S S S G
Sbjct: 927 TSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLT 986
Query: 509 TLPVAVALTESVNAYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNI 568
+ PV+ L + A P +T S P + TS PT +
Sbjct: 987 STPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAE-GTSMPTST----PSEGS 1041
Query: 569 SRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQV 628
+ L ++ + +V S + S T VT Y + S + A ++ Y
Sbjct: 1042 TPLTRMPVSTTMVASSETSTLSTTPA--DTSTPVTTY-SQASSSSTTADGTSMPTSTYSE 1098
Query: 629 SSNGIQSTPLNLATYWKCSAST-----TDLRVDYKYNPEAMVAPSVLSNIQV-VVPVDGG 682
S + S P++ AST D + + EA +P+ + P G
Sbjct: 1099 GSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEG 1158
Query: 683 VTNMQSLP 690
T + S+P
Sbjct: 1159 TTPLASMP 1166
Score = 40.0 bits (92), Expect = 0.008
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 19/171 (11%)
Query: 357 ISRHSPVQMNRNLSNEELTK---SKPSAPPNEKGTSDLLAWDPLFGPSLDSSS------- 406
+ +PV + S+ T S P++PP+E GT+ L + P + S +
Sbjct: 2422 VDTSTPVTTSTEASSSPTTAEGTSIPTSPPSE-GTTPLASMPVSTTPVVSSEAGTLSTTP 2480
Query: 407 ---SSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTS 463
S+ +T+S+ A ++P + IV P AS S L+ I P + P S S
Sbjct: 2481 VDTSTPMTTSTEAS-SSPTTAEDIVVPISTASEG---STLLTSIPVSTTPVASPEASTLS 2536
Query: 464 PPPAAPLARAESSSSISSSA-SLSAANTPTVGVSRGPSPVSLGNQDTLPVA 513
P + +S+ ISSSA S + PT S G +P+ T P+A
Sbjct: 2537 TTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLA 2587
Score = 39.7 bits (91), Expect = 0.011
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 7/113 (6%)
Query: 402 LDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSN 461
+DS + + S +S+ PTT P S P LTS +S P + SN
Sbjct: 418 VDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTP-LTSMPVS-----TTPVASSEASN 471
Query: 462 TSPPPAAPLARAESSSSISSSASLSAANT-PTVGVSRGPSPVSLGNQDTLPVA 513
S P + +S+ SSS + N+ PT S G +P++ + T+PVA
Sbjct: 472 LSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVA 524
Score = 39.7 bits (91), Expect = 0.011
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 4/106 (3%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
+SSS T+ ++ PT+ S G+ P S + S + S ++ P S PVT+ +
Sbjct: 3259 ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQA 3318
Query: 465 PPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTL 510
+ P+A S +++ S +TP +S +PV TL
Sbjct: 3319 SSSPPIADGTS----MPTSTYSEGSTPLTNMSFSTTPVVSSEASTL 3360
Score = 38.5 bits (88), Expect = 0.024
Identities = 39/146 (26%), Positives = 64/146 (43%), Gaps = 6/146 (4%)
Query: 401 SLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTS 460
S ++SSS ++ +S PT+ S G+ P S + S + S ++ P S PVT
Sbjct: 3433 STEASSSPTIAEGTSL-PTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVT- 3490
Query: 461 NTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESV 520
TS P + AE +S +S+A +TP + +PV+ TL + +
Sbjct: 3491 -TSSPTNSSPTTAEVTSMPTSTA--GEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTF 3547
Query: 521 NAYFKGADPTKCIVKITGDMTMSFPS 546
A + +++T M MS PS
Sbjct: 3548 VTSSSQASSSPATLQVT-TMRMSTPS 3572
Score = 38.1 bits (87), Expect = 0.031
Identities = 37/144 (25%), Positives = 58/144 (40%), Gaps = 17/144 (11%)
Query: 374 LTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRP 433
LT S P + L+ P D+S+ + ++ +S+ PTT G + P
Sbjct: 2989 LTSMSVSTMPVASSEASTLSRTPA-----DTSTPVTTSTEASSSPTTAEGTGIPISTPSE 3043
Query: 434 ASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTV 493
S P L+ I P + P S S P +S+S + +S +S++ TP
Sbjct: 3044 GSTP------LTSIPVSTTPVAIPEASTLSTTP------VDSNSPVVTSTEVSSSPTPAE 3091
Query: 494 GVSRGPSPVSLGNQDTLPVAVALT 517
G S S S G+ V V+ T
Sbjct: 3092 GTSMPISTYSEGSTPLTGVPVSTT 3115
Score = 38.1 bits (87), Expect = 0.031
Identities = 51/190 (26%), Positives = 80/190 (42%), Gaps = 20/190 (10%)
Query: 346 VSIGNITLSPAISRHSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSS 405
VS +T P S S + ++S ++ S+P +GT+ + P +S
Sbjct: 3760 VSTTPVTRFPESSTPSIPSVYTSMSMTTASEGS-SSPTTLEGTTTM--------PMSTTS 3810
Query: 406 SSSSLTSSSSARPTT---PLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSP---PVT 459
S+L ++ P + P T+ PP S P LTS K +G IP + +T
Sbjct: 3811 ERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTK-AGSFSIPAEVTTIRISIT 3869
Query: 460 SNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTES 519
S S P L S++ +S S A+TP + S +P S T + VA T S
Sbjct: 3870 SERSTPLTTLLV---STTLPTSFPGASIASTPPLDTSTTFTP-STDTASTPTIPVATTIS 3925
Query: 520 VNAYFKGADP 529
V+ +G+ P
Sbjct: 3926 VSVITEGSTP 3935
Score = 37.7 bits (86), Expect = 0.041
Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 19/133 (14%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
++SSS T+ ++ PT+ + G+ P + + S + S ++ P S PVT++T
Sbjct: 666 ATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTST-- 723
Query: 465 PPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYF 524
E+SSS +++ A+ PT S G +P++ ++PV+ L S A
Sbjct: 724 ---------EASSSPTTA---DGASMPTSTPSEGSTPLT-----SMPVSKTLLTSSEAST 766
Query: 525 KGADPTKCIVKIT 537
P IT
Sbjct: 767 LSTTPLDTSTHIT 779
Score = 37.7 bits (86), Expect = 0.041
Identities = 47/189 (24%), Positives = 75/189 (39%), Gaps = 23/189 (12%)
Query: 406 SSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPP 465
SSS + ++ P + S G+ P S +TS +S ++ P S PVT++T
Sbjct: 3084 SSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTST--- 3140
Query: 466 PAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFK 525
A SS + S S+ PT S G +P++ +PV+ L S
Sbjct: 3141 ------EAHSSPTTSEGTSM-----PTSTPSEGSTPLTY-----MPVSTMLVVSSEDSTL 3184
Query: 526 GADP--TKCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFS 583
A P T V + + T S + + TS P+ + +S A ++ +
Sbjct: 3185 SATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILST 3244
Query: 584 DPSQCDSNT 592
P DSNT
Sbjct: 3245 TP--VDSNT 3251
Score = 37.4 bits (85), Expect = 0.054
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 14/109 (12%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
+S S T+ ++ PT+ S GT P S + S +++ ++ P + VT++T
Sbjct: 3377 ASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTST-- 3434
Query: 465 PPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVA 513
A SS +I+ SL PT S G +P+S+ T PVA
Sbjct: 3435 -------EASSSPTIAEGTSL-----PTSTTSEGSTPLSIMPLSTTPVA 3471
Score = 37.0 bits (84), Expect = 0.070
Identities = 52/211 (24%), Positives = 80/211 (37%), Gaps = 24/211 (11%)
Query: 361 SPVQMNRNLSNE-ELTKSKPSAPPNEKGTSDLLAWD-PLFGPSLDSSSSSSLTSSSSARP 418
+PV N ++ E T S +A TS PL S+ +++ +S +S
Sbjct: 652 TPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPL--TSMPVNTTLVASSEASTLS 709
Query: 419 TTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTS--------NTSPPPAAPL 470
TTP+ T V AS T+ S P S P+TS +S
Sbjct: 710 TTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLST 769
Query: 471 ARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQ--DTLPVAVALTESVNAYFKGAD 528
++S+ I++S S + T T G S S S G+ ++PV++ S A
Sbjct: 770 TPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTT 829
Query: 529 PTKCIVKITGDMTMSFPSGIIKVFTSNPTPA 559
P +T +S S+PTPA
Sbjct: 830 PVDSNSPVTTSTEVS----------SSPTPA 850
Score = 36.6 bits (83), Expect = 0.091
Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 406 SSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPP 465
SSS+ ++ ++ PT+ S G+ P S L S + S ++ P S PVT++T
Sbjct: 2553 SSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTE-T 2611
Query: 466 PAAPLARAESSSSISSSASLSAANT 490
++P ++S IS+ + +S + T
Sbjct: 2612 SSSPTTAKDTSMPISTPSEVSTSLT 2636
Score = 35.8 bits (81), Expect = 0.16
Identities = 33/167 (19%), Positives = 67/167 (40%), Gaps = 10/167 (5%)
Query: 356 AISRHSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSS 415
+I+ P+ + + T S P+ P + ++ G ++ S+ +S++
Sbjct: 3893 SIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTAD 3952
Query: 416 ARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP--------PPA 467
P T +V T V + P +S + + F+ P + +P P+
Sbjct: 3953 VFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPS 4012
Query: 468 APLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAV 514
P R S +S+++LSA +TP S PV+ ++ + P +
Sbjct: 4013 TP--RTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTI 4057
Score = 35.4 bits (80), Expect = 0.20
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 3/109 (2%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
+SSS T+ ++ PT+ + G+ PAS + + ++S ++ P S VT++T P
Sbjct: 312 ASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEP 371
Query: 465 PPAAPLARAESS-SSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPV 512
A A S +S S S N P + S S T+PV
Sbjct: 372 SSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEAS--TTSTIPV 418
Score = 35.4 bits (80), Expect = 0.20
Identities = 29/123 (23%), Positives = 50/123 (40%), Gaps = 4/123 (3%)
Query: 388 TSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGI 447
TS + F + +SSS T+ ++ T+ S G+ P S + S + S +
Sbjct: 413 TSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNL 472
Query: 448 NEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQ 507
+ P VT++T + P A S +++ S +TP +S PV+
Sbjct: 473 STTPVDSKTQVTTSTEASSSPPTAEVNS----MPTSTPSEGSTPLTSMSVSTMPVASSEA 528
Query: 508 DTL 510
TL
Sbjct: 529 STL 531
Score = 35.4 bits (80), Expect = 0.20
Identities = 37/154 (24%), Positives = 62/154 (40%), Gaps = 22/154 (14%)
Query: 407 SSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPP 466
SS TS ++ P + S GT P S + S + S ++ P S PVT++T
Sbjct: 1729 SSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTST---- 1784
Query: 467 AAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVA---VALTESVNAY 523
+ SS + + PT +S G +P++ + PV+ VA +E+
Sbjct: 1785 ----------EATSSPTTAEGTSIPTSTLSEGMTPLT-----STPVSHTLVANSEASTLS 1829
Query: 524 FKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPT 557
D +V T + P+ + TS P+
Sbjct: 1830 TTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPS 1863
Score = 35.4 bits (80), Expect = 0.20
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNT-- 462
++SS T+ ++ PT+ LS G P S + + + S ++ P + PV ++T
Sbjct: 1786 ATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAV 1845
Query: 463 --SPPPAAPLARAESSSSISSSASLS-AANTPTVGVS 496
SP PA + A S+ S S+A S +T TV S
Sbjct: 1846 SSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASS 1882
Score = 35.4 bits (80), Expect = 0.20
Identities = 31/144 (21%), Positives = 59/144 (40%), Gaps = 4/144 (2%)
Query: 404 SSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTS 463
+ ++SS T+ ++ PT+ S G P S + S + S ++ P + P+T++T
Sbjct: 3199 TEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTE 3258
Query: 464 PPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAY 523
+ P A S +++ S +TP + + V+ TL A T +
Sbjct: 3259 ASSSPPTAEGTS----MPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTT 3314
Query: 524 FKGADPTKCIVKITGDMTMSFPSG 547
+ A + I T T ++ G
Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEG 3338
Score = 35.0 bits (79), Expect = 0.27
Identities = 40/155 (25%), Positives = 65/155 (41%), Gaps = 12/155 (7%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
+SSS T+ ++ PT S G+ P S + S + S ++ P S P T++T
Sbjct: 1963 ASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEG 2022
Query: 465 PPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYF 524
+ A +SI +S S TP G+ + V +TL T V++
Sbjct: 2023 SSSPTTA---GGTSIQTSTP-SERTTPLAGMPVSTTLVVSSEGNTLS-----TTPVDSKT 2073
Query: 525 KGADPTKCIVKITGD---MTMSFPSGIIKVFTSNP 556
+ + T+ T + MT+S PS + TS P
Sbjct: 2074 QVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIP 2108
Score = 34.7 bits (78), Expect = 0.35
Identities = 64/294 (21%), Positives = 105/294 (35%), Gaps = 37/294 (12%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
+SSS T+ ++ PT+ S G+ S + S + S ++ P S PVT+
Sbjct: 489 ASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTT---- 544
Query: 465 PPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYF 524
SS + SSS + + PT S G +P++ +PV+ L S A
Sbjct: 545 ----------SSEASSSSTTPEGTSIPTSTPSEGSTPLT-----NMPVSTRLVVSSEAST 589
Query: 525 KGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTP--AVLCFRVKNISRLEQILPNAQLVF 582
P +T S S TS PT + + ++S ++ +++
Sbjct: 590 TSTTPADSNTFVTTSSEAS-SSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEAST 648
Query: 583 SDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLAT 642
+ DSNT VT + S A ++ Y S + S P+N
Sbjct: 649 LSTTPVDSNT--------PVTTSTEATSSSTTAEG-TSMPTSTYTEGSTPLTSMPVNTTL 699
Query: 643 YWKCSAST-----TDLRVDYKYNPEAMVAPSVLSNIQVVVPVDG-GVTNMQSLP 690
AST D + EA +P+ + G T + S+P
Sbjct: 700 VASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP 753
Score = 34.7 bits (78), Expect = 0.35
Identities = 75/352 (21%), Positives = 125/352 (35%), Gaps = 46/352 (13%)
Query: 407 SSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPP 466
SS TS ++ PT+ S G+ P S + + + S ++ P S PVT++T
Sbjct: 2200 SSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTST---- 2255
Query: 467 AAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKG 526
+ SS + + PT +S G +P++ ++PV+ L +
Sbjct: 2256 ----------EATSSPTTAEGTSIPTSTLSEGTTPLT-----SIPVSHTLVANSEVSTLS 2300
Query: 527 ADPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPS 586
P T S P + TS PT + + L ++ + +V S +
Sbjct: 2301 TTPVDSNTPFTTSTEASSPPPTAE-GTSMPTST----SSEGNTPLTRMPVSTTMVASFET 2355
Query: 587 QCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKC 646
S T VT Y + A ++ Y S + S P++
Sbjct: 2356 STLSTTPA--DTSTPVTTY-SQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSS 2412
Query: 647 SAST-----TDLRVDYKYNPEAMVAPSVLSNIQV-VVPVDGGVTNMQSLPPAIWNAEQMK 700
AST D + EA +P+ + P G T + S+P + +
Sbjct: 2413 EASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSE 2472
Query: 701 AFWKLSSISEKSENGGSGSLRAKFDLSEGPSKPTT-----LAVQFLSEGSTL 747
A LS+ + + S +E S PTT + + SEGSTL
Sbjct: 2473 A-GTLSTTPVDTSTPMTTS-------TEASSSPTTAEDIVVPISTASEGSTL 2516
Score = 34.3 bits (77), Expect = 0.45
Identities = 39/176 (22%), Positives = 64/176 (36%), Gaps = 31/176 (17%)
Query: 362 PVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTP 421
PV +S+E T S A N F + +SSSS T+ ++ PT+
Sbjct: 576 PVSTRLVVSSEASTTSTTPADSNT------------FVTTSSEASSSSTTAEGTSMPTST 623
Query: 422 LSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISS 481
S S + S + S ++ P + PVT++T + SS
Sbjct: 624 YSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTST--------------EATSS 669
Query: 482 SASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKIT 537
S + + PT + G +P++ ++PV L S A P +T
Sbjct: 670 STTAEGTSMPTSTYTEGSTPLT-----SMPVNTTLVASSEASTLSTTPVDTSTPVT 720
Score = 34.3 bits (77), Expect = 0.45
Identities = 44/179 (24%), Positives = 67/179 (37%), Gaps = 26/179 (14%)
Query: 369 LSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTS-----------SSSAR 417
LS + S P E +S A D S S S+SLTS +S
Sbjct: 2594 LSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTL 2653
Query: 418 PTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTS--------NTSPPPAAP 469
TTP+ T+V S T+ S P S P+T+ S
Sbjct: 2654 STTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLS 2713
Query: 470 LARAESSSSISSSASLSAANTPTVGVSR-------GPSPVSLGNQDTLPVAVALTESVN 521
++S+ +++SA S++ T G S G +P++ TLPVA + +V+
Sbjct: 2714 TTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVS 2772
Score = 34.3 bits (77), Expect = 0.45
Identities = 36/118 (30%), Positives = 48/118 (40%), Gaps = 31/118 (26%)
Query: 404 SSSSSSLTSSSS------------ARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIP 451
S+SSSS T+S S A P T +++ T PR SR TS P
Sbjct: 3975 STSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTP 4034
Query: 452 --------RPFSP--------PVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTV 493
RP +P +TS+T PP P A SS+ ++SAS + N V
Sbjct: 4035 HTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPP---AHSSTPPTTSASSTTVNPEAV 4089
Score = 33.1 bits (74), Expect = 1.0
Identities = 81/388 (20%), Positives = 140/388 (36%), Gaps = 40/388 (10%)
Query: 377 SKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASR 436
S P++ P+E T PL S+ S+ +S +S TTP+ T V AS
Sbjct: 500 SMPTSTPSEGST-------PL--TSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASS 550
Query: 437 PKLTSGKLSGINEIPRPFSPPVTSN--------TSPPPAAPLARAESSSSISSSASLSAA 488
T S P S P+T+ +S A+S++ +++S+ S++
Sbjct: 551 SSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSS 610
Query: 489 NTPTVGVSRGPSPVSLGNQ--DTLPVAVALTESVNAYFKGADPTKCIVKITGDMTMSFPS 546
+T G S S S ++ V+ L S A P +T T + S
Sbjct: 611 STTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT-TSTEATSS 669
Query: 547 GIIKVFTSNPTPAVLCFRVKNISRLEQILPNAQLVFSDPSQCDSNTKDFWMNMQAVTVYL 606
TS PT + + L + N LV S + S T ++
Sbjct: 670 STTAEGTSMPTSTY----TEGSTPLTSMPVNTTLVASSEASTLSTTP---VDTSTPVTTS 722
Query: 607 KKLSEQNPAASYYNVDVLKYQVSSNGIQSTPLNLATYWKCSAST-----TDLRVDYKYNP 661
+ S A ++ S + S P++ AST D +
Sbjct: 723 TEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTST 782
Query: 662 EAMVAPSVL--SNIQVVVPVDGGVTNMQSLPPAIWNAEQMKAFWKLSSISEKSENGGSG- 718
EA +P+ +++ + P +G + S+P +I +A S++S + S
Sbjct: 783 EASCSPTTTEGTSMPISTPSEGSPL-LTSIPVSITPVTSPEA----STLSTTPVDSNSPV 837
Query: 719 SLRAKFDLSEGPSKPTTLAVQFLSEGST 746
+ + S P++ T++ SEG T
Sbjct: 838 TTSTEVSSSPTPAEGTSMPTSTYSEGRT 865
Score = 33.1 bits (74), Expect = 1.0
Identities = 62/291 (21%), Positives = 107/291 (36%), Gaps = 43/291 (14%)
Query: 401 SLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTS 460
S+ +++ +S+ S TTP+ T V A TS S N P + P+TS
Sbjct: 1341 SIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTS 1400
Query: 461 ---NTSP---PPAAPLARAESSSSISSSASLSAANTPTV--GVSRGPSPVSLGNQDTLPV 512
+T+P A+ L+ +S + S A ++PT G+S S S G +
Sbjct: 1401 IPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSI 1460
Query: 513 AVALTESVNAYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTPAVLCFRVKNISRLE 572
V+ T N ++ T + + P +S+PTPA
Sbjct: 1461 PVSNTPVAN--------SEASTLSTTPVDSNSPVVTSTAVSSSPTPA------------- 1499
Query: 573 QILPNAQLVFSDPSQCDSNTKDFWMNMQAVTVYLKKLSEQNPAASYYNVDVLKYQVSSNG 632
+ S PS + +T + + TV +++ + + + V Y +S+
Sbjct: 1500 ---EGTSIAISTPS--EGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSS 1554
Query: 633 ---IQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLSNIQVVVPVD 680
T + +TY + S T L V M+ S +N P+D
Sbjct: 1555 PTTADGTSMQTSTYSEGSTPLTSLPV------STMLVVSSEANTLSTTPID 1599
Score = 32.7 bits (73), Expect = 1.3
Identities = 39/152 (25%), Positives = 61/152 (40%), Gaps = 31/152 (20%)
Query: 388 TSDLLAWDPLFGPSLDSSSSSSLTS----------SSSARPTTPLSVGTIVPPPR----- 432
TS L+ P+ P + S++ + S SSS PT S+ T R
Sbjct: 2105 TSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLT 2164
Query: 433 --PASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANT 490
P S + S +S ++ P S PVT++T A SS + S S+
Sbjct: 2165 SMPVSTTVVASSAISTLSTTPVDTSTPVTNST---------EARSSPTTSEGTSM----- 2210
Query: 491 PTVGVSRGPSPVSLGNQDTLPVAVALTESVNA 522
PT S G +P + T+PV + +++A
Sbjct: 2211 PTSTPSEGSTPFTSMPVSTMPVVTSEASTLSA 2242
Score = 32.7 bits (73), Expect = 1.3
Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 4/106 (3%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
+SSS T+ P + S G+ + P S + S + S ++ P S PVT++T
Sbjct: 2847 ASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTE- 2905
Query: 465 PPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTL 510
++P +S IS+ + +S TP + PV+ TL
Sbjct: 2906 GSSSPTTAEGTSMPISTPSEVS---TPLTSILVSTVPVAGSEASTL 2948
Score = 32.3 bits (72), Expect = 1.7
Identities = 44/184 (23%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 380 SAPPNEKGTSDLLAWDPLFGP----SLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPAS 435
S+P +GTS + P G S+ S+++ +S ++ TTP T V S
Sbjct: 1847 SSPTPAEGTS-IATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVS 1905
Query: 436 RPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGV 495
T+ S PR PP+TS P +A +E + + S +L+ TP
Sbjct: 1906 SSPTTADGSSMPTSTPREGRPPLTS--IPVSTTTVASSEIN---TLSTTLADTRTPVTTY 1960
Query: 496 SRGPSPVSLGNQDTLPVAVALTESVNAYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSN 555
S+ S + + ++P AY +G+ P + T + S S +
Sbjct: 1961 SQASSSPTTADGTSMPTP--------AYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDT 2012
Query: 556 PTPA 559
TPA
Sbjct: 2013 STPA 2016
Score = 32.3 bits (72), Expect = 1.7
Identities = 48/191 (25%), Positives = 82/191 (42%), Gaps = 29/191 (15%)
Query: 344 LKVSIGNITLSPA-ISRHSPVQMNRNLSNEELTK--SKPSAPPNEKGTSDLLAWDPLFGP 400
L VS + TLS + +PV + ++ + S P++ P+E T PL
Sbjct: 3175 LVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMT-------PL--T 3225
Query: 401 SLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTS 460
S+ S++ +S +S TTP+ T + AS T+ S P S P+TS
Sbjct: 3226 SVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTS 3285
Query: 461 NTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQ--DTLPVAVALTE 518
P++ +SS +S+ S + A+T T PV+ +Q + P+A +
Sbjct: 3286 -------MPVSTTTVASSETSTLSTTPADTST--------PVTTYSQASSSPPIADGTSM 3330
Query: 519 SVNAYFKGADP 529
+ Y +G+ P
Sbjct: 3331 PTSTYSEGSTP 3341
Score = 32.0 bits (71), Expect = 2.3
Identities = 42/189 (22%), Positives = 78/189 (41%), Gaps = 31/189 (16%)
Query: 347 SIGNITLSPAISRHSPVQMNRNLSNEELTK---SKPSAPPNEKGTSDLLAWDPLFGPSLD 403
S +I + + ++P+ + S+ T S P++ P+E T L P+ ++
Sbjct: 3237 SEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTP--LTSMPVSTTTVA 3294
Query: 404 SSSSSSL-----------TSSSSARPTTPLSVGTIVPPPRPA-----------SRPKLTS 441
SS +S+L T+ S A + P++ GT +P + S + S
Sbjct: 3295 SSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVS 3354
Query: 442 GKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSP 501
+ S ++ P S PVT++T A L+ + + ++S S TP + +P
Sbjct: 3355 SEASTLSTTPVDTSTPVTTSTE----ASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTP 3410
Query: 502 VSLGNQDTL 510
V +TL
Sbjct: 3411 VVSSEVNTL 3419
Score = 31.2 bits (69), Expect = 3.8
Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 20/143 (13%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
+SSS T S+ P + S G+ PAS K+ S + + P S PVT +
Sbjct: 194 ASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTIS--- 250
Query: 465 PPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALTESVNAYF 524
A++SSS +++ S +N+ G G +P++ +P++V L S A
Sbjct: 251 --------AQASSSPTTAEGPSLSNSAPSG---GSTPLT-----RMPLSVMLVVSSEAST 294
Query: 525 KGADPTKC-IVKITGDMTMSFPS 546
P I IT S P+
Sbjct: 295 LSTTPAATNIPVITSTEASSSPT 317
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 5/103 (4%)
Query: 399 GPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPV 458
G + ++SS T+ + PT+ S G P S + + + S ++ P + PV
Sbjct: 1427 GTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPV 1486
Query: 459 TSNT----SPPPAAPLARAESSSSISSSASLS-AANTPTVGVS 496
++T SP PA + A S+ S S+A S +T TV S
Sbjct: 1487 VTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASS 1529
Score = 31.2 bits (69), Expect = 3.8
Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 11/133 (8%)
Query: 377 SKPSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASR 436
S P++ P E+ T PL ++ S++ S +S TTP+ T V AS
Sbjct: 2681 SMPTSTPGERST-------PL--TNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASS 2731
Query: 437 PKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPTVGVS 496
T+ S P S P+TS P+A +E+S+ +++ S T + S
Sbjct: 2732 SPTTAEGTSMRISTPSDGSTPLTSIL--VSTLPVASSEASTVSTTAVDTSIPVTTSTEAS 2789
Query: 497 RGPSPVSLGNQDT 509
P+ + + T
Sbjct: 2790 SSPTTAEVTSMPT 2802
Score = 31.2 bits (69), Expect = 3.8
Identities = 38/153 (24%), Positives = 57/153 (37%), Gaps = 21/153 (13%)
Query: 380 SAPPNEKGTSDLLAW-----DPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPA 434
S+P +GTS ++ PL G + ++ +S S+ S TTP+ T V A
Sbjct: 3085 SSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTS--SAISTLSTTPVDTSTPVTTSTEA 3142
Query: 435 SRPKLTSGKLSGINEIPRPFSPPVT--------------SNTSPPPAAPLARAESSSSIS 480
TS S P S P+T S S P +S+ +
Sbjct: 3143 HSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEAT 3202
Query: 481 SSASLSAANTPTVGVSRGPSPVSLGNQDTLPVA 513
SS + + PT S G +P++ PVA
Sbjct: 3203 SSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVA 3235
Score = 30.4 bits (67), Expect = 6.6
Identities = 34/165 (20%), Positives = 69/165 (41%), Gaps = 11/165 (6%)
Query: 405 SSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNT-- 462
+SSS T+ ++ PT+ S + P + + S + ++ P S PVT++T
Sbjct: 2788 ASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKA 2847
Query: 463 --SPPPA----APLARAESSSSISSSASLS---AANTPTVGVSRGPSPVSLGNQDTLPVA 513
SP A P++ A S++ +S +S A++ +S P S+ + +
Sbjct: 2848 SSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGS 2907
Query: 514 VALTESVNAYFKGADPTKCIVKITGDMTMSFPSGIIKVFTSNPTP 558
+ T + + P++ +T + + P + T + TP
Sbjct: 2908 SSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTP 2952
Score = 30.4 bits (67), Expect = 6.6
Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 11/117 (9%)
Query: 406 SSSSLTSSSSARPTTPLSVGTI-VPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
++S+ T S+++ P T SV T V P +SRP + + IP F PP S+T P
Sbjct: 4022 TTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITS-----HTIPPTF-PPAHSSTPP 4075
Query: 465 PPAAPLA----RAESSSSISSSASLSAANTPTVGVSRGPSPVSLGNQDTLPVAVALT 517
+A A ++ + + S + PTV + P+ ++ + T V T
Sbjct: 4076 TTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRT 4132
Score = 30.0 bits (66), Expect = 8.6
Identities = 40/167 (23%), Positives = 64/167 (38%), Gaps = 13/167 (7%)
Query: 357 ISRHSPVQMNRNLSNEELTKSKPSAPPN--EKGTSDLLAWDPLFGPSLDSSSSSSLTSSS 414
+ +PV + ++ T S P + +GT+ L + +L ++S S S++
Sbjct: 2245 VDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIP--VSHTLVANSEVSTLSTT 2302
Query: 415 SARPTTPLSVGTIV--PPPRPASRPKLTSGKLSGINEIPR-PFSPPV-----TSNTSPPP 466
TP + T PPP TS G + R P S + TS S P
Sbjct: 2303 PVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTP 2362
Query: 467 AAPLARAESSSSISSS-ASLSAANTPTVGVSRGPSPVSLGNQDTLPV 512
A + S SS + + PT S G +P++ T+PV
Sbjct: 2363 ADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPV 2409
Score = 30.0 bits (66), Expect = 8.6
Identities = 51/214 (23%), Positives = 80/214 (37%), Gaps = 35/214 (16%)
Query: 333 NSHHTMASLDELKVSIGNITLSPAIS---RHSPVQMNR--NLSNEELTKSKPSAPPNEKG 387
+S T A + + S + T +P S H+PV + LS + S P +
Sbjct: 2789 SSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKAS 2848
Query: 388 TSDLLAWDPLFGPSLDSSSSSSLTS-----------SSSARPTTPLSVGTIVPPPRPASR 436
+S A + S S S+ LTS +S TTP+ V S
Sbjct: 2849 SSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSS 2908
Query: 437 PKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESS----------SSISSSASLS 486
T+ S P S P+TS P+A +E+S + +++SA S
Sbjct: 2909 SPTTAEGTSMPISTPSEVSTPLTSIL--VSTVPVAGSEASTLSTTPVDTRTPVTTSAEAS 2966
Query: 487 AANTPTVGVSRGPS-------PVSLGNQDTLPVA 513
++ T G S S P++ + T+PVA
Sbjct: 2967 SSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVA 3000
>gi|21070997 stromal interaction molecule 1 precursor [Homo sapiens]
Length = 685
Score = 46.2 bits (108), Expect = 1e-04
Identities = 83/384 (21%), Positives = 148/384 (38%), Gaps = 60/384 (15%)
Query: 74 DVFKTSTEKLANCHLDLVRKLQELIKEVQKYGEEQVKSHKKTKEEVAGTLEAVQTIQSIT 133
+V K EK ++L ++ + +KE+++ G E +S +K EE ++ +
Sbjct: 276 EVEKVHLEKKLRDEINLAKQEAQRLKELRE-GTENERSRQKYAEE---------ELEQVR 325
Query: 134 QALQKSKENY--NAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVEKYALAKADF 191
+AL+K+++ ++ E L+K E+E KK +L V K K
Sbjct: 326 EALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIK- 384
Query: 192 EQKMTETAQVHEEFINNMANTTVESLIQKFAESKGTGKERPGLIEFEECDTASAVEGI-K 250
+++ T H +++ + + L K A S+ T R L +++ + + +
Sbjct: 385 KKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNN 444
Query: 251 PRKRKTFALPGI------IKKEKDAESVECPDADSLN---IPDVDEEGYSIKPETNQNDT 301
P A I + A + D D ++ + + + S++ Q T
Sbjct: 445 PGIHSLVAALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLT 504
Query: 302 KENHFYSS------SDSDSEDEEPKKYRIEIKP-------------MHPNNSHHTMASLD 342
+ H S SDS+S + R+ KP M N SH + +
Sbjct: 505 EPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGSHRLIEGVH 564
Query: 343 ELKVSIGNITLSPAISRHSPVQMNRNLSN-EELTKSKPSAPPNEKGTSDLLAWDPLFGPS 401
+ + + SPA+++ + + +N L L + PSAPP P
Sbjct: 565 PGSL-VEKLPDSPALAKKALLALNHGLDKAHSLMELSPSAPPGG-------------SPH 610
Query: 402 LDSSSSSSLTSSSSARPTTPLSVG 425
LDSS S S SS P TP VG
Sbjct: 611 LDSSRSH---SPSSPDPDTPSPVG 631
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 45.8 bits (107), Expect = 2e-04
Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 27/160 (16%)
Query: 355 PAISRHSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSS------- 407
P++ P+Q+ +L++ L APP+ S L A L P+L ++ S
Sbjct: 381 PSLQTIPPIQVPHSLTSPSL-----QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435
Query: 408 ---SSLTSSSSARPTTPLSVGTIVPPPRPASRPKLTSGKLSGINEIPRPFSPPVTSNTSP 464
+SLTS S T P S P PAS P TS SP V+ +SP
Sbjct: 436 QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS------------LSPAVSPLSSP 483
Query: 465 PPAAPLARAESSSSISSSASLSAANTPTVGVSRGPSPVSL 504
PL S +S S A LS+ P + +P SL
Sbjct: 484 LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Score = 38.1 bits (87), Expect = 0.031
Identities = 44/156 (28%), Positives = 69/156 (44%), Gaps = 24/156 (15%)
Query: 352 TLSPAISR-HSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFGPSLDSSSS--- 407
+LSPA+S SP+ ++ + L P AP + L P L++ SS
Sbjct: 472 SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS-----------LIMPPLETQSSLAP 520
Query: 408 SSLTSSSSARPTTPL-SVGTIVPPP-RPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPP 465
SL + ++ T PL ++ ++ PPP + AS P T + P P P + T+PP
Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP 580
Query: 466 PAAPLARAESSSSISSSASLSAANTPTVGVSRGPSP 501
P P S ++ A + A+ P G+ PSP
Sbjct: 581 PETP----SSIATPPPQAPPALASPPLQGL---PSP 609
Score = 36.6 bits (83), Expect = 0.091
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 15/122 (12%)
Query: 396 PLFGPSLDSSSSSSLTSSSSARPTTPL-SVGTIVPPPRPASRPKLTSGKLSGINEIPRPF 454
P GP S ++ S + ARP P + T +P P S P T L+ P P
Sbjct: 294 PALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP----PSPS 349
Query: 455 SPPVTSNTSPPPAAPLARA-ESSSSISSSASLSAANTPTVGVSRG---------PSPVSL 504
+PP PPA P ++A S ++ A S P + V PSP++L
Sbjct: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409
Query: 505 GN 506
+
Sbjct: 410 SS 411
Score = 36.6 bits (83), Expect = 0.091
Identities = 43/162 (26%), Positives = 62/162 (38%), Gaps = 31/162 (19%)
Query: 356 AISRHSPVQMNRNLSNEELTKSKPSAPPNEKGTSDLLAWDPLFG-PSLD----SSSSSSL 410
+++ HSP +L L APP+ + L PL PSL ++S+ L
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553
Query: 411 TSSSSARPTTPLSVGTIVPP----------------PRPASRPKLTSGKLSGINEIPRPF 454
T+ P P PP P P + P L S L G+
Sbjct: 554 TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP------ 607
Query: 455 SPPVTSNTSPPPAAP----LARAESSSSISSSASLSAANTPT 492
SPP++ +PPP AP L ++ S +S LS TP+
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649
Score = 35.0 bits (79), Expect = 0.27
Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Query: 379 PSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPPRPASRPK 438
PSA P + L A PS +S S +++ + PL+ + PP P + P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746
Query: 439 LTSGKLSGINEIPRPFSPPVTSNTSPP---PAAPLAR 472
++ P +PP+ SPP P +PLA+
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783
Score = 33.5 bits (75), Expect = 0.77
Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 15/125 (12%)
Query: 379 PSAPPNEKGTSDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTP--LSVGTIVPPPRPASR 436
P P+ T A L P L S L+ ++ P P L++ + PP P +
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639
Query: 437 PKLT--------SGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAA 488
P L+ + ++ + PFSPP SPP AP + +S +S SA+ +
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPP----PSPPVQAPFS-PPASPPVSPSATPPSQ 694
Query: 489 NTPTV 493
P++
Sbjct: 695 APPSL 699
Score = 32.3 bits (72), Expect = 1.7
Identities = 30/122 (24%), Positives = 50/122 (40%), Gaps = 13/122 (10%)
Query: 381 APPNEKGTSDLLAWDPLFGPSLDSSSSSS--LTSSSSARPTTPLSVGTIVPPPRPASRPK 438
APP+ + L PL PS + ++ + L + + P +P PP P P
Sbjct: 632 APPSPPASPPL---SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688
Query: 439 LTSGKLSGIN------EIPR--PFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANT 490
T + + ++P P SPP++ + +PPP AP A + S S +
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748
Query: 491 PT 492
P+
Sbjct: 749 PS 750
Score = 31.2 bits (69), Expect = 3.8
Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 4/110 (3%)
Query: 375 TKSKPSAPPNEKGT---SDLLAWDPLFGPSLDSSSSSSLTSSSSARPTTPLSVGTIVPPP 431
TK++P PP+ T + L PL P + S S S P+ P + + PP
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371
Query: 432 RPASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISS 481
+ P L I I P S S +PP L+ ++++S+ S
Sbjct: 372 M-TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
Score = 30.0 bits (66), Expect = 8.6
Identities = 33/129 (25%), Positives = 46/129 (35%), Gaps = 19/129 (14%)
Query: 374 LTKSKPSAPPNEKGTSDLLAWDPLFGP-SLDSSSSSSLTSSSSARPTTPLSVGTIVPPPR 432
L P APP LA PL P S +S S ++ S + L+V + P
Sbjct: 614 LATPPPQAPPX-------LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 433 PASRPKLTSGKLSGINEIPRPFSPPVTSNTSPPPAAPLARAESSSSISSSASLSAANTPT 492
P P + + PFSPP + SP P S ++ S +P
Sbjct: 667 PPPSPPVQA-----------PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715
Query: 493 VGVSRGPSP 501
+ S P P
Sbjct: 716 MSPSATPPP 724
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,871,624
Number of Sequences: 37866
Number of extensions: 1473499
Number of successful extensions: 12397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 890
Number of HSP's that attempted gapping in prelim test: 9079
Number of HSP's gapped (non-prelim): 3295
length of query: 777
length of database: 18,247,518
effective HSP length: 110
effective length of query: 667
effective length of database: 14,082,258
effective search space: 9392866086
effective search space used: 9392866086
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.