Search of human proteins with 225637477

Search of human proteins with 225637477

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
         (687 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225637477 solute carrier organic anion transporter family, me...  1389   0.0  
gi|225637473 solute carrier organic anion transporter family, me...  1361   0.0  
gi|225637475 solute carrier organic anion transporter family, me...  1207   0.0  
gi|39777594 solute carrier organic anion transporter family memb...   351   1e-96
gi|38679890 solute carrier organic anion transporter family, mem...   331   1e-90
gi|222831575 solute carrier organic anion transporter family, me...   319   6e-87
gi|222831573 solute carrier organic anion transporter family, me...   319   6e-87
gi|223634012 solute carrier organic anion transporter family, me...   288   1e-77
gi|6005820 solute carrier organic anion transporter family, memb...   288   1e-77
gi|188528663 solute carrier organic anion transporter family, me...   270   3e-72
gi|9790233 solute carrier organic anion transporter family, memb...   268   1e-71
gi|225543525 solute carrier organic anion transporter family, me...   259   4e-69
gi|10835099 organic anion transporting polypeptide A [Homo sapiens]   259   4e-69
gi|19913403 organic anion transporting polypeptide A [Homo sapiens]   259   4e-69
gi|225543118 solute carrier organic anion transporter family, me...   259   8e-69
gi|8394291 solute carrier organic anion transporter family, memb...   259   8e-69
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom...   247   2e-65
gi|225543116 solute carrier organic anion transporter family, me...   223   4e-58
gi|93277099 solute carrier organic anion transporter family, mem...   215   1e-55
gi|223634014 solute carrier organic anion transporter family, me...   208   2e-53
gi|225543114 solute carrier organic anion transporter family, me...   197   3e-50
gi|194239645 spinster homolog 3 [Homo sapiens]                         50   9e-06
gi|29568105 transmembrane protein with EGF-like and two follista...    46   1e-04
gi|185136021 spinster homolog 2 [Homo sapiens]                         43   8e-04
gi|215490102 spinster homolog 1 isoform 3 [Homo sapiens]               39   0.016
gi|215490096 spinster homolog 1 isoform 1 [Homo sapiens]               39   0.016
gi|14042968 spinster homolog 1 isoform 1 [Homo sapiens]                39   0.016
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa...    38   0.036
gi|215490100 spinster homolog 1 isoform 2 [Homo sapiens]               38   0.036
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ...    36   0.14 

>gi|225637477 solute carrier organic anion transporter family,
           member 5A1 isoform 2 [Homo sapiens]
          Length = 687

 Score = 1389 bits (3594), Expect = 0.0
 Identities = 687/687 (100%), Positives = 687/687 (100%)

Query: 1   MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
           MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
Sbjct: 1   MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60

Query: 61  FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
           FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
Sbjct: 61  FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120

Query: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
           YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
Sbjct: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180

Query: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
           VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
Sbjct: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240

Query: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
           NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
Sbjct: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300

Query: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
           YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
Sbjct: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360

Query: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
           VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD
Sbjct: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420

Query: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
           LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP
Sbjct: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480

Query: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
           SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT
Sbjct: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540

Query: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
           GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE
Sbjct: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600

Query: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
           CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF
Sbjct: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660

Query: 661 ITACAQPSAIIVTLSIHSYSNLLWSSH 687
           ITACAQPSAIIVTLSIHSYSNLLWSSH
Sbjct: 661 ITACAQPSAIIVTLSIHSYSNLLWSSH 687


>gi|225637473 solute carrier organic anion transporter family,
           member 5A1 isoform 1 [Homo sapiens]
          Length = 848

 Score = 1361 bits (3522), Expect = 0.0
 Identities = 674/674 (100%), Positives = 674/674 (100%)

Query: 1   MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
           MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
Sbjct: 1   MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60

Query: 61  FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
           FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
Sbjct: 61  FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120

Query: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
           YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
Sbjct: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180

Query: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
           VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
Sbjct: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240

Query: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
           NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
Sbjct: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300

Query: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
           YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
Sbjct: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360

Query: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
           VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD
Sbjct: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420

Query: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
           LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP
Sbjct: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480

Query: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
           SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT
Sbjct: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540

Query: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
           GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE
Sbjct: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600

Query: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
           CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF
Sbjct: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660

Query: 661 ITACAQPSAIIVTL 674
           ITACAQPSAIIVTL
Sbjct: 661 ITACAQPSAIIVTL 674


>gi|225637475 solute carrier organic anion transporter family,
           member 5A1 isoform 3 [Homo sapiens]
          Length = 793

 Score = 1207 bits (3123), Expect = 0.0
 Identities = 607/674 (90%), Positives = 611/674 (90%), Gaps = 55/674 (8%)

Query: 1   MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
           MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
Sbjct: 1   MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60

Query: 61  FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
           FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
Sbjct: 61  FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120

Query: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
           YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
Sbjct: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180

Query: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
           VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
Sbjct: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240

Query: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
           NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
Sbjct: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300

Query: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
           YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
Sbjct: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360

Query: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
           VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVR 
Sbjct: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRG 420

Query: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
           +                                           +P++   I  G     
Sbjct: 421 V-----------------------------------------IIVPSAGVGIVLG----- 434

Query: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
                    GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT
Sbjct: 435 ---------GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 485

Query: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
           GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE
Sbjct: 486 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 545

Query: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
           CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF
Sbjct: 546 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 605

Query: 661 ITACAQPSAIIVTL 674
           ITACAQPSAIIVTL
Sbjct: 606 ITACAQPSAIIVTL 619


>gi|39777594 solute carrier organic anion transporter family member
           4A1 [Homo sapiens]
          Length = 722

 Score =  351 bits (901), Expect = 1e-96
 Identities = 202/554 (36%), Positives = 295/554 (53%), Gaps = 50/554 (9%)

Query: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
           VL   +  L  +C   F+Q + V+G++++VIT++ERRY L S +SGL+ S +DI   + +
Sbjct: 98  VLNTPKGILFFLCAAAFLQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCL 157

Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
            FVSYFGG G +P WL  G LL+  G+ +FALPHF +  Y++ EL+A          G  
Sbjct: 158 TFVSYFGGSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEV-ELDA----------GVR 206

Query: 243 TATLEPPA-CPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLY 301
           T    P A C   + G +   Y  +F+  Q L G+G+TP+YTLG TYLD+NVK   S +Y
Sbjct: 207 TCPANPGAVCADSTSGLSR--YQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVY 264

Query: 302 LAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
           +AI Y    LGPA GYL+GG L+  Y +      L    P ++G WW GFL    A F  
Sbjct: 265 IAIFYTAAILGPAAGYLIGGALLNIYTEMGRRTELTTESPLWVGAWWVGFLGSGAAAFFT 324

Query: 362 IFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDL 421
             P+  +P++LP        ++++V   ++   LK+ S        + S+  FGK +RDL
Sbjct: 325 AVPILGYPRQLP------GSQRYAVMRAAEMHQLKDSSRG------EASNPDFGKTIRDL 372

Query: 422 PRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPS 481
           P +   +L N TF+ + L+   E+ ++T   TF PKF+ESQF + AS A+   G ++VP+
Sbjct: 373 PLSIWLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPA 432

Query: 482 AGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTG 541
            G G  LGG+ + KL+L      K  + C+ VSLL    +F + C S+ + G+   Y  G
Sbjct: 433 GGGGTFLGGFFVNKLRLRGSAVIKFCLFCTVVSLLGI-LVFSLHCPSVPMAGVTASY-GG 490

Query: 542 PSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLST-GIRNYTE 600
             L   H NLT  CN  C C+   Y PVCGSDG+ YF+ C AGC  +   +  G + Y +
Sbjct: 491 SLLPEGHLNLTAPCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRD 550

Query: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
           C+C                     I +   +  G+A +GKC  TC      LVF+F+V F
Sbjct: 551 CSC---------------------IPQNLSSGFGHATAGKCTSTCQRKPLLLVFIFVVIF 589

Query: 661 ITACAQPSAIIVTL 674
            T  +   A+  TL
Sbjct: 590 FTFLSSIPALTATL 603


>gi|38679890 solute carrier organic anion transporter family, member
           4C1 [Homo sapiens]
          Length = 724

 Score =  331 bits (849), Expect = 1e-90
 Identities = 206/604 (34%), Positives = 310/604 (51%), Gaps = 54/604 (8%)

Query: 65  DSSGHQELKQGPNPL-APSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCLYVV 123
           ++S  QEL++   P  +P PS PS    + +   R      F   S        +CL   
Sbjct: 42  ENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRC 101

Query: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183
            T    FL+  C L   Q ++V+G ++  I+T+E+RY +KSS +GL+ S +DI   ++ +
Sbjct: 102 NTPGG-FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSL 160

Query: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNST 243
           FVS+FG RG +P WLA    +I  GA +F+LP F S  Y++  L      D      NST
Sbjct: 161 FVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLF----EDTCVTTRNST 216

Query: 244 ATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLA 303
           +      C   +   ++++YV  FI  Q+L+G G TP+YTLG  +LDD+V    SSLY+ 
Sbjct: 217 S------CTSSTSSLSNYLYV--FILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268

Query: 304 IMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLD--QNDPRFIGNWWSGFLLCAIAMFLV 361
             Y M  LGPA+GY+LGG L+  Y+D       D  ++DPR++G WW GFLL  I  + +
Sbjct: 269 TGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSL 328

Query: 362 IFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDL 421
           I P   FPK LP                   ++   K++ + Q++   + + FGK ++D 
Sbjct: 329 IIPFSCFPKHLP----------------GTAEIQAGKTSQAHQSNSN-ADVKFGKSIKDF 371

Query: 422 PRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPS 481
           P A   ++ N  F+ + LS ++E+ I T F TF+PKFIE+QFG+ +S A+   G +++P 
Sbjct: 372 PAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPG 431

Query: 482 AGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTG 541
           A +G +LGG+++ K ++  + + K A+  SGV+L          CE+    G++  Y   
Sbjct: 432 AALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGT 491

Query: 542 PSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTEC 601
             L     NL   CN NC C    Y PVCG DG+ YF+PC AGC N        + Y  C
Sbjct: 492 GEL----GNLIAPCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNP-VAHRKPKVYYNC 545

Query: 602 TCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFI 661
           +C++ +  IT               +T+  E   A +GKC+  C  L  FL   FIV   
Sbjct: 546 SCIERKTEITS------------TAETFGFE---AKAGKCETHCAKLPIFLCIFFIVIIF 590

Query: 662 TACA 665
           T  A
Sbjct: 591 TFMA 594


>gi|222831575 solute carrier organic anion transporter family,
           member 3A1 isoform 1 [Homo sapiens]
          Length = 710

 Score =  319 bits (817), Expect = 6e-87
 Identities = 190/560 (33%), Positives = 298/560 (53%), Gaps = 50/560 (8%)

Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
           + FLV  C L   Q   V  YL SV+TT+ERR++L+S++ G++ S F+IGNL +++FVSY
Sbjct: 40  KIFLVSECALMLAQGT-VGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSY 98

Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQ--ELNASAPNDGLCQGGNSTAT 245
           FG RG RP  +  GG+++A GA L ALP F++  Y+ +  E+   A    +C    S   
Sbjct: 99  FGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGD 158

Query: 246 LEPP---ACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYL 302
             P     C   +  N  ++   L I AQ+L+G+G+TP+  LG +Y+DD+V++++SSLY+
Sbjct: 159 EGPDPDLICRNRTATNMMYL---LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYI 215

Query: 303 AIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAM 358
            I++ M   GPA G++LG      YVD      + + +  +DPR+IG WW GFLLC   +
Sbjct: 216 GILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALL 275

Query: 359 FLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDV 418
           F     MF FP+ LPP  +   + + ++ +  + +  K  +       +  SS    + +
Sbjct: 276 FFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQL 335

Query: 419 RDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVII 478
           R +P+    +LSN  F  + L+   E A+V  F  F+ K++E QF +  S+A+   G+  
Sbjct: 336 RVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTA 395

Query: 479 VPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPY 538
           +P A +GI LGG ++KKL L A  + ++AM+ + VS  C+ +   +GC++  + G+ +PY
Sbjct: 396 IPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPY 455

Query: 539 --TTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIR 596
             +T P   +   +    CN NC C+   + PVCG+DGITY + C AGC NS NL     
Sbjct: 456 GNSTAPGSAL---DPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGC-NSTNL----- 506

Query: 597 NYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT-C-NTLIPFLVF 654
             T C C                      + T   EN   V GKC    C    + FL  
Sbjct: 507 --TGCAC----------------------LTTVPAENATVVPGKCPSPGCQEAFLTFLCV 542

Query: 655 LFIVTFITACAQPSAIIVTL 674
           + I + I A AQ  ++I+ +
Sbjct: 543 MCICSLIGAMAQTPSVIILI 562


>gi|222831573 solute carrier organic anion transporter family,
           member 3A1 isoform 2 [Homo sapiens]
          Length = 692

 Score =  319 bits (817), Expect = 6e-87
 Identities = 190/560 (33%), Positives = 298/560 (53%), Gaps = 50/560 (8%)

Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
           + FLV  C L   Q   V  YL SV+TT+ERR++L+S++ G++ S F+IGNL +++FVSY
Sbjct: 40  KIFLVSECALMLAQGT-VGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSY 98

Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQ--ELNASAPNDGLCQGGNSTAT 245
           FG RG RP  +  GG+++A GA L ALP F++  Y+ +  E+   A    +C    S   
Sbjct: 99  FGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGD 158

Query: 246 LEPP---ACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYL 302
             P     C   +  N  ++   L I AQ+L+G+G+TP+  LG +Y+DD+V++++SSLY+
Sbjct: 159 EGPDPDLICRNRTATNMMYL---LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYI 215

Query: 303 AIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAM 358
            I++ M   GPA G++LG      YVD      + + +  +DPR+IG WW GFLLC   +
Sbjct: 216 GILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALL 275

Query: 359 FLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDV 418
           F     MF FP+ LPP  +   + + ++ +  + +  K  +       +  SS    + +
Sbjct: 276 FFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQL 335

Query: 419 RDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVII 478
           R +P+    +LSN  F  + L+   E A+V  F  F+ K++E QF +  S+A+   G+  
Sbjct: 336 RVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTA 395

Query: 479 VPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPY 538
           +P A +GI LGG ++KKL L A  + ++AM+ + VS  C+ +   +GC++  + G+ +PY
Sbjct: 396 IPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPY 455

Query: 539 --TTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIR 596
             +T P   +   +    CN NC C+   + PVCG+DGITY + C AGC NS NL     
Sbjct: 456 GNSTAPGSAL---DPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGC-NSTNL----- 506

Query: 597 NYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT-C-NTLIPFLVF 654
             T C C                      + T   EN   V GKC    C    + FL  
Sbjct: 507 --TGCAC----------------------LTTVPAENATVVPGKCPSPGCQEAFLTFLCV 542

Query: 655 LFIVTFITACAQPSAIIVTL 674
           + I + I A AQ  ++I+ +
Sbjct: 543 MCICSLIGAMAQTPSVIILI 562


>gi|223634012 solute carrier organic anion transporter family,
           member 2B1 isoform 2 [Homo sapiens]
          Length = 687

 Score =  288 bits (737), Expect = 1e-77
 Identities = 187/581 (32%), Positives = 282/581 (48%), Gaps = 66/581 (11%)

Query: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
           V  + + F++C   L   Q LM+SGYL S I+T+E+R+ L S  SGLL S  ++GN  ++
Sbjct: 22  VFHNIKLFVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 80

Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
           VFVSYFG R  RP  +  G +L+A    L  LPHFIS PY+      ++P D + Q   +
Sbjct: 81  VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN---TSPED-MPQDFKA 136

Query: 243 TATLEPPACPKDSGGN---------NHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNV 293
           +  L   + P  +  N          H   V +   AQ L+G+G  PI   G +Y+DD  
Sbjct: 137 SLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFA 196

Query: 294 KKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWS 349
              NS LYL I++ +  +GP + + LG L++  YVD    P   + L   DPR++G WW 
Sbjct: 197 HNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWL 256

Query: 350 GFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKV 409
           GFL+ A A+ L   P F FPK++ P+ K++ + +  V AV+D    K K + S+Q+  + 
Sbjct: 257 GFLIAAGAVALAAIPYFFFPKEM-PKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGES 315

Query: 410 SSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKF 458
           +    G           + ++  PR  ++ L +  FL V LS    S++     TF+PKF
Sbjct: 316 TKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKF 375

Query: 459 IESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCF 518
           +E QF I AS A++  G +  PS  VGIV+GG ++K+L LG      L ++   + L   
Sbjct: 376 LERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFS 435

Query: 519 STLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITY 577
             LF +GC S  + GI    +  P L      L+ SC   C C +  + PVC  S  + Y
Sbjct: 436 LPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEY 490

Query: 578 FNPCLAGC---VNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENG 634
             PC AGC   V    L      YT C+CV                           E  
Sbjct: 491 ITPCHAGCSSWVVQDALDNSQVFYTNCSCVV--------------------------EGN 524

Query: 635 YAVSGKCKRTCNTL-IPFLVFLFIVTFITACAQPSAIIVTL 674
             ++G C  TC+ L +PFL+ + + + +       + ++ L
Sbjct: 525 PVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLIL 565


>gi|6005820 solute carrier organic anion transporter family, member
           2B1 isoform 1 [Homo sapiens]
          Length = 709

 Score =  288 bits (737), Expect = 1e-77
 Identities = 187/581 (32%), Positives = 282/581 (48%), Gaps = 66/581 (11%)

Query: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
           V  + + F++C   L   Q LM+SGYL S I+T+E+R+ L S  SGLL S  ++GN  ++
Sbjct: 44  VFHNIKLFVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 102

Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
           VFVSYFG R  RP  +  G +L+A    L  LPHFIS PY+      ++P D + Q   +
Sbjct: 103 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN---TSPED-MPQDFKA 158

Query: 243 TATLEPPACPKDSGGN---------NHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNV 293
           +  L   + P  +  N          H   V +   AQ L+G+G  PI   G +Y+DD  
Sbjct: 159 SLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFA 218

Query: 294 KKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWS 349
              NS LYL I++ +  +GP + + LG L++  YVD    P   + L   DPR++G WW 
Sbjct: 219 HNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWL 278

Query: 350 GFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKV 409
           GFL+ A A+ L   P F FPK++ P+ K++ + +  V AV+D    K K + S+Q+  + 
Sbjct: 279 GFLIAAGAVALAAIPYFFFPKEM-PKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGES 337

Query: 410 SSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKF 458
           +    G           + ++  PR  ++ L +  FL V LS    S++     TF+PKF
Sbjct: 338 TKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKF 397

Query: 459 IESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCF 518
           +E QF I AS A++  G +  PS  VGIV+GG ++K+L LG      L ++   + L   
Sbjct: 398 LERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFS 457

Query: 519 STLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITY 577
             LF +GC S  + GI    +  P L      L+ SC   C C +  + PVC  S  + Y
Sbjct: 458 LPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEY 512

Query: 578 FNPCLAGC---VNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENG 634
             PC AGC   V    L      YT C+CV                           E  
Sbjct: 513 ITPCHAGCSSWVVQDALDNSQVFYTNCSCVV--------------------------EGN 546

Query: 635 YAVSGKCKRTCNTL-IPFLVFLFIVTFITACAQPSAIIVTL 674
             ++G C  TC+ L +PFL+ + + + +       + ++ L
Sbjct: 547 PVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLIL 587


>gi|188528663 solute carrier organic anion transporter family,
           member 2A1 [Homo sapiens]
          Length = 643

 Score =  270 bits (690), Expect = 3e-72
 Identities = 163/501 (32%), Positives = 260/501 (51%), Gaps = 41/501 (8%)

Query: 118 RCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIG 177
           RC   V  + + F++C   L   Q L+ S Y  S +TTIE+R+ L SS SGL+ S  +I 
Sbjct: 22  RCARSVFGNIKVFVLCQGLLQLCQ-LLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEIS 80

Query: 178 NLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQ---IQELNASAPND 234
           N ++++FVSYFG R  RP  + +GGL +A GA +  LPHF+S PYQ       N S    
Sbjct: 81  NAILIIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRLQA 140

Query: 235 GLCQGGNSTATLEPPACPKDSGG-----NNHWVYVALFICAQILIGMGSTPIYTLGPTYL 289
            LCQ       L P  C   +       ++ W    L + AQ+L G+G+ PI   G +Y+
Sbjct: 141 ELCQ--KHWQDLPPSKCHSTTQNPQKETSSMW---GLMVVAQLLAGIGTVPIQPFGISYV 195

Query: 290 DDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIG 345
           DD  +  NS LY++I++ +   GPA GYLLG +++  +VD        V+L   DPR+IG
Sbjct: 196 DDFSEPSNSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIG 255

Query: 346 NWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQA 405
            WW G L+ +  + L  FP F FP+ +P   K+         A +D+      +   E+A
Sbjct: 256 AWWLGLLISSALLVLTSFPFFFFPRAMPIGAKR-------APATADE------ARKLEEA 302

Query: 406 DKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGI 465
             + S + F   ++  P   +R+L N  F+ V L+    S+++    TF+ KF+E Q+G 
Sbjct: 303 KSRGSLVDF---IKRFPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGT 359

Query: 466 PASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVG 525
            A+ A+   G + +P+A +G++ GG ++K+     +   ++A     +S++    LF +G
Sbjct: 360 SAAYANFLIGAVNLPAAALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMG 419

Query: 526 CESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGC 585
           C +  +  +  P T+  S   P    + +C  +C C    + PVCG +GI Y +PC AGC
Sbjct: 420 CSTPTVAEVYPPSTS--SSIHPQ---SPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGC 474

Query: 586 --VNSGNLSTGIRNYTECTCV 604
             +N  + ++    Y  C+CV
Sbjct: 475 SNINMSSATSKQLIYLNCSCV 495


>gi|9790233 solute carrier organic anion transporter family, member
           1B3 [Homo sapiens]
          Length = 702

 Score =  268 bits (686), Expect = 1e-71
 Identities = 177/527 (33%), Positives = 282/527 (53%), Gaps = 47/527 (8%)

Query: 101 LSKTFSVSSALAMLQERRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSV-ITTIERR 159
           L+KT + S++    + RRC        + FL  + F    +AL   G +  + IT IERR
Sbjct: 7   LNKT-AESASSEKKKTRRC-----NGFKMFLAALSFSYIAKAL--GGIIMKISITQIERR 58

Query: 160 YSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFIS 219
           + + SS +GL+   F+IGNL+V+VFVSYFG +  RP  + +G LL+  G+ L +LPHF  
Sbjct: 59  FDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFM 118

Query: 220 PPYQIQE-------------LNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVAL 266
             Y+  +             L+    N  L   G S   +E   C K+S G++ W+YV +
Sbjct: 119 GYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKD-CVKES-GSHMWIYVFM 176

Query: 267 FICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGF 326
                +L G+G TPI  LG +Y+DD  K+ +SSLYL  +  +G +GP +G+ LG L    
Sbjct: 177 ---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKM 233

Query: 327 YVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKK 382
           YVD      + + +   D R++G WW GFL+  +   +   P F  PK  P + +K++K 
Sbjct: 234 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKI 292

Query: 383 KFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTF-LFVSLSY 441
             S+  +  +D   + +N + Q  K V+     K+V    ++   IL+N  + +F+ L+ 
Sbjct: 293 SLSLHVLKTNDDRNQTANLTNQG-KNVT-----KNVTGFFQSLKSILTNPLYVIFLLLTL 346

Query: 442 TAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGAR 501
              S+ + +F T++ K++E Q+G  AS+A+   G+I +P+   G+ LGG+IIKK KL   
Sbjct: 347 LQVSSFIGSF-TYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLV 405

Query: 502 ESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGC 561
             AK + + S +S L     F + CES ++ G+ + Y    S+          CN  C C
Sbjct: 406 GIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNC 465

Query: 562 KIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYT---ECTCVQ 605
              ++EPVCG++GITY +PCLAGC +    S+GI+ +T    C+CV+
Sbjct: 466 DESQWEPVCGNNGITYLSPCLAGCKS----SSGIKKHTVFYNCSCVE 508


>gi|225543525 solute carrier organic anion transporter family,
           member 1B1 [Homo sapiens]
          Length = 691

 Score =  259 bits (663), Expect = 4e-69
 Identities = 167/494 (33%), Positives = 264/494 (53%), Gaps = 46/494 (9%)

Query: 137 LTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPL 196
           L+FI   + +  + S I  IERR+ + SS  G +   F+IGNL+V+VFVSYFG +  RP 
Sbjct: 36  LSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPK 95

Query: 197 WLAVGGLLIAFGAALFALPHFISPPYQI-QELNASAPNDGLCQGGNSTATLEP------- 248
            + +G  ++  G  L ALPHF    Y+  +E N ++         NST+TL         
Sbjct: 96  LIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSE-------NSTSTLSTCLINQIL 148

Query: 249 -----------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKEN 297
                        C K+SG +  W+YV +     +L G+G TPI  LG +Y+DD  K+ +
Sbjct: 149 SLNRASPEIVGKGCLKESG-SYMWIYVFM---GNMLRGIGETPIVPLGLSYIDDFAKEGH 204

Query: 298 SSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLL 353
           SSLYL I+  +  +GP +G+ LG L    YVD      + + +   D R++G WW  FL+
Sbjct: 205 SSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLV 264

Query: 354 CAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMG 413
             +   +   P F  P+  P + +K++K   S+  +  +D   + +N + Q  K ++   
Sbjct: 265 SGLFSIISSIPFFFLPQT-PNKPQKERKASLSLHVLETNDEKDQTANLTNQG-KNIT--- 319

Query: 414 FGKDVRDLPRAAVRILSNMTF-LFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASI 472
             K+V    ++   IL+N  + +FV L+    S+ + AF T++ K++E Q+G P+S A+I
Sbjct: 320 --KNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAF-TYVFKYVEQQYGQPSSKANI 376

Query: 473 YTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLG 532
             GVI +P    G+ LGGYIIKK KL     AK +   + +SL  +   F + CE+ ++ 
Sbjct: 377 LLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVA 436

Query: 533 GINIPYTTGPSLTMPHRNLTGS-CNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNL 591
           G+ + Y     +T  HR++  S CN +C C   ++EPVCG++GITY +PCLAGC +S   
Sbjct: 437 GLTMTYDGNNPVTS-HRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGN 495

Query: 592 STGIRNYTECTCVQ 605
              I  Y  C+C++
Sbjct: 496 KKPIVFY-NCSCLE 508


>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
          Length = 670

 Score =  259 bits (663), Expect = 4e-69
 Identities = 158/497 (31%), Positives = 260/497 (52%), Gaps = 39/497 (7%)

Query: 128 RCFLVCMCFLTFIQALMVS-----GYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
           RC      FL  I    VS      Y++S++T IER++++ +S  G +   F+IGNL+++
Sbjct: 14  RCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLI 73

Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLC 237
           +FVSYFG +  RP+ + +G +++  G  L +LPHF+   Y+ +       N S+ N  LC
Sbjct: 74  IFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLC 132

Query: 238 QGGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVK 294
               +     T +P  C K+   +  WVYV   +   I+ GMG TPI  LG +Y++D  K
Sbjct: 133 MENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAK 188

Query: 295 KENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSG 350
            ENS LY+ ++     +GP +G LL       YVD      + + +   D R++G WW G
Sbjct: 189 FENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFG 248

Query: 351 FLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVS 410
           FL+CA    L   P F  P  LP       K+    +A    D++K ++ + ++ + K  
Sbjct: 249 FLICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKE 297

Query: 411 SMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNA 470
             G  KD   LP       + +  LF+ +S    +A V   I+F+PK++E Q+GI +S+A
Sbjct: 298 KYGITKDF--LPFMKSLSCNPIYMLFILVSVIQFNAFVN-MISFMPKYLEQQYGISSSDA 354

Query: 471 SIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESIN 530
               G+  +P   +G ++GG I+KK K+  +++A +    S +  L +   F++ CE+ +
Sbjct: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414

Query: 531 LGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGN 590
           + GIN  Y   P       ++   CNV+C C    ++PVCG++G++Y + CLAGC  S  
Sbjct: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS-- 472

Query: 591 LSTGIRN-YTECTCVQS 606
           + TGI   +  C+C+Q+
Sbjct: 473 IGTGINMVFQNCSCIQT 489


>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
          Length = 670

 Score =  259 bits (663), Expect = 4e-69
 Identities = 158/497 (31%), Positives = 260/497 (52%), Gaps = 39/497 (7%)

Query: 128 RCFLVCMCFLTFIQALMVS-----GYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
           RC      FL  I    VS      Y++S++T IER++++ +S  G +   F+IGNL+++
Sbjct: 14  RCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLI 73

Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLC 237
           +FVSYFG +  RP+ + +G +++  G  L +LPHF+   Y+ +       N S+ N  LC
Sbjct: 74  IFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLC 132

Query: 238 QGGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVK 294
               +     T +P  C K+   +  WVYV   +   I+ GMG TPI  LG +Y++D  K
Sbjct: 133 MENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAK 188

Query: 295 KENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSG 350
            ENS LY+ ++     +GP +G LL       YVD      + + +   D R++G WW G
Sbjct: 189 FENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFG 248

Query: 351 FLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVS 410
           FL+CA    L   P F  P  LP       K+    +A    D++K ++ + ++ + K  
Sbjct: 249 FLICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKE 297

Query: 411 SMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNA 470
             G  KD   LP       + +  LF+ +S    +A V   I+F+PK++E Q+GI +S+A
Sbjct: 298 KYGITKDF--LPFMKSLSCNPIYMLFILVSVIQFNAFVN-MISFMPKYLEQQYGISSSDA 354

Query: 471 SIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESIN 530
               G+  +P   +G ++GG I+KK K+  +++A +    S +  L +   F++ CE+ +
Sbjct: 355 IFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSS 414

Query: 531 LGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGN 590
           + GIN  Y   P       ++   CNV+C C    ++PVCG++G++Y + CLAGC  S  
Sbjct: 415 VVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS-- 472

Query: 591 LSTGIRN-YTECTCVQS 606
           + TGI   +  C+C+Q+
Sbjct: 473 IGTGINMVFQNCSCIQT 489


>gi|225543118 solute carrier organic anion transporter family,
           member 1C1 isoform 1 [Homo sapiens]
          Length = 730

 Score =  259 bits (661), Expect = 8e-69
 Identities = 157/509 (30%), Positives = 248/509 (48%), Gaps = 59/509 (11%)

Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
           + FL  + F+ F +AL   GYL S IT IERR+ + SS  G++   F+IGNL+V+ FVSY
Sbjct: 43  KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101

Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
           FG +  RP  +  G +++  G  L A+P F    Y+ +  + S+         NST ++ 
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152

Query: 248 P----------------------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLG 285
           P                        C  D+  ++ W+YV L     +L G+G TPI  LG
Sbjct: 153 PCLLESSSQLPVSVMEKSKSKISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLG 208

Query: 286 PTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDP 341
             YLDD   ++N++ Y+  +  +  +GP  G+LLG L    YVD      + + +   DP
Sbjct: 209 IAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDP 268

Query: 342 RFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVL 395
           +++G WW G+L+  I   L   P +  PK LP    ++      +K KF +D  +D    
Sbjct: 269 QWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD---- 324

Query: 396 KEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFI 455
                  +  + K+  M      RD   +   +  N  +     + T +   +   +T+ 
Sbjct: 325 ---YQTPQGENAKIMEMA-----RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYK 376

Query: 456 PKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSL 515
           PK+IE Q+G  +S A+   G+I +P+  +GI  GG ++KK ++    +AKL +  S    
Sbjct: 377 PKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGY 436

Query: 516 LCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGI 575
           L F +LF +GCE+ ++ G+ + Y     ++   R L   CN  C C   ++EP+CG +GI
Sbjct: 437 LLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGI 496

Query: 576 TYFNPCLAGCVNSGNLSTGIRNYTECTCV 604
           TY + CLAGC  S      I  Y  CTCV
Sbjct: 497 TYVSACLAGCQTSNRSGKNIIFY-NCTCV 524


>gi|8394291 solute carrier organic anion transporter family, member
           1C1 isoform 2 [Homo sapiens]
          Length = 712

 Score =  259 bits (661), Expect = 8e-69
 Identities = 157/509 (30%), Positives = 248/509 (48%), Gaps = 59/509 (11%)

Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
           + FL  + F+ F +AL   GYL S IT IERR+ + SS  G++   F+IGNL+V+ FVSY
Sbjct: 43  KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101

Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
           FG +  RP  +  G +++  G  L A+P F    Y+ +  + S+         NST ++ 
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152

Query: 248 P----------------------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLG 285
           P                        C  D+  ++ W+YV L     +L G+G TPI  LG
Sbjct: 153 PCLLESSSQLPVSVMEKSKSKISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLG 208

Query: 286 PTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDP 341
             YLDD   ++N++ Y+  +  +  +GP  G+LLG L    YVD      + + +   DP
Sbjct: 209 IAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDP 268

Query: 342 RFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVL 395
           +++G WW G+L+  I   L   P +  PK LP    ++      +K KF +D  +D    
Sbjct: 269 QWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD---- 324

Query: 396 KEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFI 455
                  +  + K+  M      RD   +   +  N  +     + T +   +   +T+ 
Sbjct: 325 ---YQTPQGENAKIMEMA-----RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYK 376

Query: 456 PKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSL 515
           PK+IE Q+G  +S A+   G+I +P+  +GI  GG ++KK ++    +AKL +  S    
Sbjct: 377 PKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGY 436

Query: 516 LCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGI 575
           L F +LF +GCE+ ++ G+ + Y     ++   R L   CN  C C   ++EP+CG +GI
Sbjct: 437 LLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGI 496

Query: 576 TYFNPCLAGCVNSGNLSTGIRNYTECTCV 604
           TY + CLAGC  S      I  Y  CTCV
Sbjct: 497 TYVSACLAGCQTSNRSGKNIIFY-NCTCV 524


>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
           sapiens]
          Length = 640

 Score =  247 bits (631), Expect = 2e-65
 Identities = 160/469 (34%), Positives = 240/469 (51%), Gaps = 30/469 (6%)

Query: 154 TTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFA 213
           T IERR+ + SS  GL+   F+IGNL V+VFVSYFG +  RP  + +G  L+  G+ L A
Sbjct: 6   TQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMA 65

Query: 214 LPHFISPPYQIQELNASAPNDGLCQG------------GNSTATLEPPACPKDSGGNNHW 261
           LPHF    Y+  +     P++                   + + +    C K+SG ++ W
Sbjct: 66  LPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG-SHMW 124

Query: 262 VYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGG 321
           +YV +     +L G+G TPI  LG +Y+DD  K+ +SSLYL  + VMG  G    ++LG 
Sbjct: 125 IYVFM---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGS 181

Query: 322 LLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHK 377
           L    YVD      + + +   D R++G WW GFL+  I   +   P F  P  L P +K
Sbjct: 182 LFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLP--LNP-NK 238

Query: 378 KKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFV 437
            +K++K S+       VLK     ++ A+         K+V    ++   IL+N  ++  
Sbjct: 239 PQKERKVSLFL----HVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIF 294

Query: 438 SLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLK 497
            +      +   A +T+I K +E Q+G  AS  +   GV+ +P+  +G+  GGYIIKK K
Sbjct: 295 VIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFK 354

Query: 498 LGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGS-CN 556
           L     AKLA   + V LL     F + CES ++ G+ + Y  G S    H ++  S CN
Sbjct: 355 LSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTY-DGNSPVRSHVDVPLSYCN 413

Query: 557 VNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQ 605
             C C   ++EPVCG++GITY +PCLAGC +S      I  Y  C+CV+
Sbjct: 414 SECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFY-NCSCVE 461


>gi|225543116 solute carrier organic anion transporter family,
           member 1C1 isoform 3 [Homo sapiens]
          Length = 663

 Score =  223 bits (569), Expect = 4e-58
 Identities = 142/487 (29%), Positives = 227/487 (46%), Gaps = 64/487 (13%)

Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
           + FL  + F+ F +AL   GYL S IT IERR+ + SS  G++   F+IGNL+V+ FVSY
Sbjct: 43  KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101

Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
           FG +  RP  +  G +++  G  L A+P F    Y+ +  + S+         NST ++ 
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152

Query: 248 PPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYV 307
           P                    C  +L      P+  +         +K  S +    +  
Sbjct: 153 P--------------------C--LLESSSQLPVSVM---------EKSKSKISNGCVQT 181

Query: 308 MGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIF 363
           +  +GP  G+LLG L    YVD      + + +   DP+++G WW G+L+  I   L   
Sbjct: 182 VAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAV 241

Query: 364 PMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKD 417
           P +  PK LP    ++      +K KF +D  +D           +  + K+  M     
Sbjct: 242 PFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD-------YQTPQGENAKIMEMA---- 290

Query: 418 VRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVI 477
            RD   +   +  N  +     + T +   +   +T+ PK+IE Q+G  +S A+   G+I
Sbjct: 291 -RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLI 349

Query: 478 IVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIP 537
            +P+  +GI  GG ++KK ++    +AKL +  S    L F +LF +GCE+ ++ G+ + 
Sbjct: 350 NIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVS 409

Query: 538 YTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRN 597
           Y     ++   R L   CN  C C   ++EP+CG +GITY + CLAGC  S      I  
Sbjct: 410 YQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIF 469

Query: 598 YTECTCV 604
           Y  CTCV
Sbjct: 470 Y-NCTCV 475


>gi|93277099 solute carrier organic anion transporter family, member
           6A1 [Homo sapiens]
          Length = 719

 Score =  215 bits (547), Expect = 1e-55
 Identities = 138/533 (25%), Positives = 241/533 (45%), Gaps = 56/533 (10%)

Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
           RCF++  C L   Q + V G +   I   ++ Y LK+ E   L   +DI + +V +F+++
Sbjct: 106 RCFMIFYCILLICQGV-VFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAF 164

Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPN--DGLCQGGNSTAT 245
           +G R ++ +W      LI  G+ L A P        I E N  +    + +C+       
Sbjct: 165 YGDR-KKVIWFVASSFLIGLGSLLCAFP-------SINEENKQSKVGIEDICE------E 210

Query: 246 LEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
           ++  +  + SG +    Y++ FI  Q + G+   P+Y LG T++D+NV   ++ +YL I 
Sbjct: 211 IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIA 270

Query: 306 YVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQND--PRFIGNWWSGFLLCAIAMFLVIF 363
                +G A+GY+LG  L+    +  +  +   N+  P ++  WW  FL  A+  +  + 
Sbjct: 271 ECTSMIGYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLI 330

Query: 364 PMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPR 423
           P+  FP  +P   + K +K+  +                   D ++  +  G +++DL  
Sbjct: 331 PLSCFPNNMPGSTRIKARKRKQLHFF----------------DSRLKDLKLGTNIKDLCA 374

Query: 424 AAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAG 483
           A   ++ N   + ++LS   E  ++     F+P ++E+QF +  + A+   G++++P   
Sbjct: 375 ALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGA 434

Query: 484 VGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPS 543
           +G +LGG I+  L++  +   +  M+ S +SL+    +  V C  +   GIN  Y     
Sbjct: 435 LGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGK 494

Query: 544 LTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTC 603
           L     NLT  CN  C C    Y  +CG D I YF+PC AGC  S       + Y  C+C
Sbjct: 495 L----GNLTAPCNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNCSC 549

Query: 604 VQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLF 656
           ++   +IT    G     R                GKC   C  L  F+ F+F
Sbjct: 550 IK-EGLITADAEGDFIDAR---------------PGKCDAKCYKLPLFIAFIF 586


>gi|223634014 solute carrier organic anion transporter family,
           member 2B1 isoform 3 [Homo sapiens]
          Length = 565

 Score =  208 bits (529), Expect = 2e-53
 Identities = 141/466 (30%), Positives = 214/466 (45%), Gaps = 67/466 (14%)

Query: 229 ASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTY 288
           ASAP++G C     T                H   V +   AQ L+G+G  PI   G +Y
Sbjct: 25  ASAPSNGNCSSYTET---------------QHLSVVGIMFVAQTLLGVGGVPIQPFGISY 69

Query: 289 LDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFI 344
           +DD     NS LYL I++ +  +GP + + LG L++  YVD    P   + L   DPR++
Sbjct: 70  IDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWV 129

Query: 345 GNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQ 404
           G WW GFL+ A A+ L   P F FPK++P + K++ + +  V AV+D    K K + S+Q
Sbjct: 130 GAWWLGFLIAAGAVALAAIPYFFFPKEMP-KEKRELQFRRKVLAVTDSPARKGKDSPSKQ 188

Query: 405 ADKKVSSMGFG-----------KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFIT 453
           +  + +    G           + ++  PR  ++ L +  FL V LS    S++     T
Sbjct: 189 SPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMAT 248

Query: 454 FIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGV 513
           F+PKF+E QF I AS A++  G +  PS  VGIV+GG ++K+L LG      L ++   +
Sbjct: 249 FLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLL 308

Query: 514 SLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-S 572
            L     LF +GC S  + GI    +  P L      L+ SC   C C +  + PVC  S
Sbjct: 309 CLFFSLPLFFIGCSSHQIAGITHQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPS 363

Query: 573 DGITYFNPCLAGC---VNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTY 629
             + Y  PC AGC   V    L      YT C+CV                         
Sbjct: 364 TRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVV------------------------ 399

Query: 630 LNENGYAVSGKCKRTCNTL-IPFLVFLFIVTFITACAQPSAIIVTL 674
             E    ++G C  TC+ L +PFL+ + + + +       + ++ L
Sbjct: 400 --EGNPVLAGSCDSTCSHLVVPFLLLVSLGSALACLTHTPSFMLIL 443


>gi|225543114 solute carrier organic anion transporter family,
           member 1C1 isoform 4 [Homo sapiens]
          Length = 612

 Score =  197 bits (501), Expect = 3e-50
 Identities = 123/429 (28%), Positives = 198/429 (46%), Gaps = 58/429 (13%)

Query: 208 GAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEP------------------- 248
           G  L A+P F    Y+ +  + S+         NST ++ P                   
Sbjct: 4   GTLLIAMPQFFMEQYKYERYSPSS---------NSTLSISPCLLESSSQLPVSVMEKSKS 54

Query: 249 ---PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
                C  D+  ++ W+YV L     +L G+G TPI  LG  YLDD   ++N++ Y+  +
Sbjct: 55  KISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCV 110

Query: 306 YVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
             +  +GP  G+LLG L    YVD      + + +   DP+++G WW G+L+  I   L 
Sbjct: 111 QTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLA 170

Query: 362 IFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFG 415
             P +  PK LP    ++      +K KF +D  +D           +  + K+  M   
Sbjct: 171 AVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTD-------YQTPQGENAKIMEMA-- 221

Query: 416 KDVRDLPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTG 475
              RD   +   +  N  +     + T +   +   +T+ PK+IE Q+G  +S A+   G
Sbjct: 222 ---RDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIG 278

Query: 476 VIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGIN 535
           +I +P+  +GI  GG ++KK ++    +AKL +  S    L F +LF +GCE+ ++ G+ 
Sbjct: 279 LINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLT 338

Query: 536 IPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGI 595
           + Y     ++   R L   CN  C C   ++EP+CG +GITY + CLAGC  S      I
Sbjct: 339 VSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNI 398

Query: 596 RNYTECTCV 604
             Y  CTCV
Sbjct: 399 IFY-NCTCV 406


>gi|194239645 spinster homolog 3 [Homo sapiens]
          Length = 512

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 73/361 (20%), Positives = 132/361 (36%), Gaps = 103/361 (28%)

Query: 149 LSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFG 208
           ++ V+  I+  + +  + +GLL + F    L+      Y G R  R   ++ G +L+  G
Sbjct: 65  IAGVLLDIQEVFQISDNHAGLLQTVFVSCLLLSAPVFGYLGDRHSRKATMSFG-ILLWSG 123

Query: 209 AALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFI 268
           A L +   FISP Y                                      W    LF 
Sbjct: 124 AGLSS--SFISPRYS-------------------------------------W----LFF 140

Query: 269 CAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYV 328
            ++ ++G GS    T+ PT L D   ++  +  LA+ Y+   +G  +GY+LG  +     
Sbjct: 141 LSRGIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVLGSAV----- 195

Query: 329 DPRNPVHLDQNDPRFIGNW-WSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVD 387
                           GNW W+  ++  +    +I  +   P   PPR   + + + +V 
Sbjct: 196 ------------TMLTGNWRWALRVMPCLEAVALILLILLVPD--PPRGAAETQGEGAVG 241

Query: 388 AVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTFLFVSLSYTAESAI 447
                                     + +DVR L +       N +F++ +L  TA + +
Sbjct: 242 GFRS---------------------SWCEDVRYLGK-------NWSFVWSTLGVTAMAFV 273

Query: 448 VTAFITFIPKFIESQ----------FGIPASNA-SIYTGVIIVPSAGVGIVLGGYIIKKL 496
             A   + PKF+             F  P SN  S+  G + + +  +G++LG    ++ 
Sbjct: 274 TGALGFWAPKFLLEARVVHGLQPPCFQEPCSNPDSLIFGALTIMTGVIGVILGAEAARRY 333

Query: 497 K 497
           K
Sbjct: 334 K 334


>gi|29568105 transmembrane protein with EGF-like and two
           follistatin-like domains 1 [Homo sapiens]
          Length = 380

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 22/107 (20%)

Query: 556 NVNCGCKI----HEYEPVCGSDGITYFNPCL---AGCVNSGNLSTGIRNYTECTCVQSRQ 608
           NV C C I    + + PVC SDG +Y NPC    A C+    +   IR+   CT      
Sbjct: 185 NVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQID--IRHLGHCTDTDDTS 242

Query: 609 VI---------TPPTVGQRSQLRVVIVKTYL----NENGYAVSGKCK 642
           ++          P       Q   V +  ++    N NGY + GKC+
Sbjct: 243 LLGKKDDGLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCIHGKCE 289



 Score = 30.4 bits (67), Expect = 5.7
 Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 3/28 (10%)

Query: 557 VNCGCKIH---EYEPVCGSDGITYFNPC 581
           + C C+      Y PVCGS+G TY N C
Sbjct: 95  LKCACQFQCHTNYIPVCGSNGDTYQNEC 122


>gi|185136021 spinster homolog 2 [Homo sapiens]
          Length = 549

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 39/172 (22%), Positives = 64/172 (37%), Gaps = 44/172 (25%)

Query: 149 LSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFG 208
           ++ V+  I++ + +K   +GLL S F    +V      Y G R  R + L+ G   I F 
Sbjct: 122 VAGVLLDIQQHFGVKDRGAGLLQSVFICSFMVAAPIFGYLGDRFNRKVILSCG---IFFW 178

Query: 209 AALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFI 268
           +A+     FI   Y                                      W    L +
Sbjct: 179 SAVTFSSSFIPQQY-------------------------------------FW----LLV 197

Query: 269 CAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLG 320
            ++ L+G+G     T+ PT + D   K   +L L++ Y    LG  +GY+ G
Sbjct: 198 LSRGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITG 249


>gi|215490102 spinster homolog 1 isoform 3 [Homo sapiens]
          Length = 476

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 42/194 (21%), Positives = 73/194 (37%), Gaps = 45/194 (23%)

Query: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
           S   +  +C++  +   M    ++ V+  IE+ +++  S SGL+ + F    +V+     
Sbjct: 58  SALIVAVLCYINLLN-YMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFG 116

Query: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATL 246
           Y G R  R  +L  GG  IAF + +     FI                            
Sbjct: 117 YLGDRYNRK-YLMCGG--IAFWSLVTLGSSFIP--------------------------- 146

Query: 247 EPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMY 306
                     G + W    L +  + L+G+G     T+ PT + D    +  S  L+I Y
Sbjct: 147 ----------GEHFW----LLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFY 192

Query: 307 VMGALGPAVGYLLG 320
               +G  +GY+ G
Sbjct: 193 FAIPVGSGLGYIAG 206


>gi|215490096 spinster homolog 1 isoform 1 [Homo sapiens]
          Length = 528

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 42/194 (21%), Positives = 73/194 (37%), Gaps = 45/194 (23%)

Query: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
           S   +  +C++  +   M    ++ V+  IE+ +++  S SGL+ + F    +V+     
Sbjct: 58  SALIVAVLCYINLLN-YMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFG 116

Query: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATL 246
           Y G R  R  +L  GG  IAF + +     FI                            
Sbjct: 117 YLGDRYNRK-YLMCGG--IAFWSLVTLGSSFIP--------------------------- 146

Query: 247 EPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMY 306
                     G + W    L +  + L+G+G     T+ PT + D    +  S  L+I Y
Sbjct: 147 ----------GEHFW----LLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFY 192

Query: 307 VMGALGPAVGYLLG 320
               +G  +GY+ G
Sbjct: 193 FAIPVGSGLGYIAG 206


>gi|14042968 spinster homolog 1 isoform 1 [Homo sapiens]
          Length = 528

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 42/194 (21%), Positives = 73/194 (37%), Gaps = 45/194 (23%)

Query: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
           S   +  +C++  +   M    ++ V+  IE+ +++  S SGL+ + F    +V+     
Sbjct: 58  SALIVAVLCYINLLN-YMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFG 116

Query: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATL 246
           Y G R  R  +L  GG  IAF + +     FI                            
Sbjct: 117 YLGDRYNRK-YLMCGG--IAFWSLVTLGSSFIP--------------------------- 146

Query: 247 EPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMY 306
                     G + W    L +  + L+G+G     T+ PT + D    +  S  L+I Y
Sbjct: 147 ----------GEHFW----LLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFY 192

Query: 307 VMGALGPAVGYLLG 320
               +G  +GY+ G
Sbjct: 193 FAIPVGSGLGYIAG 206


>gi|4504619 insulin-like growth factor binding protein 7 [Homo
           sapiens]
          Length = 282

 Score = 37.7 bits (86), Expect = 0.036
 Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 5/58 (8%)

Query: 559 CGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTEC---TCVQSRQVITPP 613
           C CK     PVCGSDG TY + C     +    S G +  T+    TC Q   ++TPP
Sbjct: 111 CVCKSRY--PVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPP 166


>gi|215490100 spinster homolog 1 isoform 2 [Homo sapiens]
          Length = 455

 Score = 37.7 bits (86), Expect = 0.036
 Identities = 39/172 (22%), Positives = 65/172 (37%), Gaps = 44/172 (25%)

Query: 149 LSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFG 208
           ++ V+  IE+ +++  S SGL+ + F    +V+     Y G R  R  +L  GG  IAF 
Sbjct: 6   VAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFGYLGDRYNRK-YLMCGG--IAFW 62

Query: 209 AALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFI 268
           + +     FI                                      G + W    L +
Sbjct: 63  SLVTLGSSFIP-------------------------------------GEHFW----LLL 81

Query: 269 CAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLG 320
             + L+G+G     T+ PT + D    +  S  L+I Y    +G  +GY+ G
Sbjct: 82  LTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAG 133


>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
           sapiens]
          Length = 97

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 566 YEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTC 603
           Y+P+CG++ ITY NPC+  CV S      IR Y +  C
Sbjct: 61  YQPICGTNFITYDNPCIL-CVESLKSHGRIRFYHDGKC 97


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,288,224
Number of Sequences: 37866
Number of extensions: 1283809
Number of successful extensions: 4853
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 4659
Number of HSP's gapped (non-prelim): 164
length of query: 687
length of database: 18,247,518
effective HSP length: 109
effective length of query: 578
effective length of database: 14,120,124
effective search space: 8161431672
effective search space used: 8161431672
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.