Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 225637475
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
(793 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225637475 solute carrier organic anion transporter family, me... 1617 0.0
gi|225637473 solute carrier organic anion transporter family, me... 1566 0.0
gi|225637477 solute carrier organic anion transporter family, me... 1207 0.0
gi|39777594 solute carrier organic anion transporter family memb... 337 2e-92
gi|38679890 solute carrier organic anion transporter family, mem... 331 1e-90
gi|222831573 solute carrier organic anion transporter family, me... 331 2e-90
gi|222831575 solute carrier organic anion transporter family, me... 328 9e-90
gi|9790233 solute carrier organic anion transporter family, memb... 300 3e-81
gi|188528663 solute carrier organic anion transporter family, me... 292 7e-79
gi|225543525 solute carrier organic anion transporter family, me... 286 5e-77
gi|8394291 solute carrier organic anion transporter family, memb... 283 3e-76
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 283 6e-76
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 283 6e-76
gi|225543118 solute carrier organic anion transporter family, me... 275 9e-74
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 271 2e-72
gi|225543116 solute carrier organic anion transporter family, me... 248 2e-65
gi|93277099 solute carrier organic anion transporter family, mem... 226 8e-59
gi|225543114 solute carrier organic anion transporter family, me... 214 3e-55
gi|223634012 solute carrier organic anion transporter family, me... 191 3e-48
gi|6005820 solute carrier organic anion transporter family, memb... 191 3e-48
gi|223634014 solute carrier organic anion transporter family, me... 135 2e-31
gi|29568105 transmembrane protein with EGF-like and two follista... 46 2e-04
gi|194239645 spinster homolog 3 [Homo sapiens] 44 6e-04
gi|185136021 spinster homolog 2 [Homo sapiens] 43 0.001
gi|215490102 spinster homolog 1 isoform 3 [Homo sapiens] 39 0.019
gi|215490096 spinster homolog 1 isoform 1 [Homo sapiens] 39 0.019
gi|14042968 spinster homolog 1 isoform 1 [Homo sapiens] 39 0.019
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 38 0.042
gi|215490100 spinster homolog 1 isoform 2 [Homo sapiens] 38 0.042
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ... 36 0.16
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 1617 bits (4187), Expect = 0.0
Identities = 793/793 (100%), Positives = 793/793 (100%)
Query: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
Sbjct: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
Query: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
Sbjct: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
Query: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
Sbjct: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
Query: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
Sbjct: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
Query: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
Sbjct: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
Query: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
Sbjct: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
Query: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRG 420
VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRG
Sbjct: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRG 420
Query: 421 VIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGIN 480
VIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGIN
Sbjct: 421 VIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGIN 480
Query: 481 IPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGI 540
IPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGI
Sbjct: 481 IPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGI 540
Query: 541 RNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFL 600
RNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFL
Sbjct: 541 RNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFL 600
Query: 601 FIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCML 660
FIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCML
Sbjct: 601 FIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCML 660
Query: 661 WQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREF 720
WQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREF
Sbjct: 661 WQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREF 720
Query: 721 PLSTVSERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADP 780
PLSTVSERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADP
Sbjct: 721 PLSTVSERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADP 780
Query: 781 GLEESPAALEPPS 793
GLEESPAALEPPS
Sbjct: 781 GLEESPAALEPPS 793
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 1566 bits (4055), Expect = 0.0
Identities = 781/848 (92%), Positives = 785/848 (92%), Gaps = 55/848 (6%)
Query: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
Sbjct: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
Query: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
Sbjct: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
Query: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
Sbjct: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
Query: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
Sbjct: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
Query: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
Sbjct: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
Query: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
Sbjct: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
Query: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRG 420
VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVR
Sbjct: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
Query: 421 V-----------------------------------------IIVPSAGVGIVLG----- 434
+ +P++ I G
Sbjct: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
Query: 435 ---------GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 485
GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT
Sbjct: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
Query: 486 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 545
GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE
Sbjct: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
Query: 546 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 605
CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF
Sbjct: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
Query: 606 ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC 665
ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC
Sbjct: 661 ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC 720
Query: 666 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV 725
GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV
Sbjct: 721 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQREFPLSTV 780
Query: 726 SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES 785
SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES
Sbjct: 781 SERVGHPDNARTRSCPAFSTQGEFHEETGLQKGIQCAAQTYPGPFPEAISSSADPGLEES 840
Query: 786 PAALEPPS 793
PAALEPPS
Sbjct: 841 PAALEPPS 848
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 1207 bits (3123), Expect = 0.0
Identities = 607/674 (90%), Positives = 611/674 (90%), Gaps = 55/674 (8%)
Query: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA
Sbjct: 1 MDEGTGLQPGAGEQLEAPATAEAVQERCEPETLRSKSLPVLSSASCRPSLSPTSGDANPA 60
Query: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL
Sbjct: 61 FGCVDSSGHQELKQGPNPLAPSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCL 120
Query: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV
Sbjct: 121 YVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLV 180
Query: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG
Sbjct: 181 VVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGG 240
Query: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL
Sbjct: 241 NSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSL 300
Query: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL
Sbjct: 301 YLAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFL 360
Query: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRG 420
VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVR
Sbjct: 361 VIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRD 420
Query: 421 V-----------------------------------------IIVPSAGVGIVLG----- 434
+ +P++ I G
Sbjct: 421 LPRAAVRILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVP 480
Query: 435 ---------GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 485
GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT
Sbjct: 481 SAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTT 540
Query: 486 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 545
GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE
Sbjct: 541 GPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTE 600
Query: 546 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 605
CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF
Sbjct: 601 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 660
Query: 606 ITACAQPSAIIVTL 619
ITACAQPSAIIVTL
Sbjct: 661 ITACAQPSAIIVTL 674
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 337 bits (865), Expect = 2e-92
Identities = 217/651 (33%), Positives = 315/651 (48%), Gaps = 108/651 (16%)
Query: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
VL + L +C F+Q + V+G++++VIT++ERRY L S +SGL+ S +DI + +
Sbjct: 98 VLNTPKGILFFLCAAAFLQGMTVNGFINTVITSLERRYDLHSYQSGLIASSYDIAACLCL 157
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
FVSYFGG G +P WL G LL+ G+ +FALPHF + Y++ EL+A G
Sbjct: 158 TFVSYFGGSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEV-ELDA----------GVR 206
Query: 243 TATLEPPA-CPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLY 301
T P A C + G + Y +F+ Q L G+G+TP+YTLG TYLD+NVK S +Y
Sbjct: 207 TCPANPGAVCADSTSGLSR--YQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSCSPVY 264
Query: 302 LAIMYVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
+AI Y LGPA GYL+GG L+ Y + L P ++G WW GFL A F
Sbjct: 265 IAIFYTAAILGPAAGYLIGGALLNIYTEMGRRTELTTESPLWVGAWWVGFLGSGAAAFFT 324
Query: 362 IFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRGV 421
P+ +P++LP ++++V ++ LK+ S + S+ FGK +R +
Sbjct: 325 AVPILGYPRQLP------GSQRYAVMRAAEMHQLKDSSRG------EASNPDFGKTIRDL 372
Query: 422 -------------IIVPSAGV---------------------------GIVLGGYI---- 437
I++ AG L GY+
Sbjct: 373 PLSIWLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVVPA 432
Query: 438 -----------IKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTG 486
+ KL+L K + C+ VSLL +F + C S+ + G+ Y G
Sbjct: 433 GGGGTFLGGFFVNKLRLRGSAVIKFCLFCTVVSLLGI-LVFSLHCPSVPMAGVTASY-GG 490
Query: 487 PSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLST-GIRNYTE 545
L H NLT CN C C+ Y PVCGSDG+ YF+ C AGC + + G + Y +
Sbjct: 491 SLLPEGHLNLTAPCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVYRD 550
Query: 546 CTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTF 605
C+C I + + G+A +GKC TC LVF+F+V F
Sbjct: 551 CSC---------------------IPQNLSSGFGHATAGKCTSTCQRKPLLLVFIFVVIF 589
Query: 606 ITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQEC 665
T + A+ TLR V D +R FALG+Q++++R L IP PI FG VID C+LWQ +C
Sbjct: 590 FTFLSSIPALTATLRCVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQDQC 649
Query: 666 GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK---YKEDGLQ 713
G QGSC Y ++ + K +G +F +A + K DGL+
Sbjct: 650 GQQGSCLVYQNSAMSRYILIMGLLYKVLGVLFFAIACFLYKPLSESSDGLE 700
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 331 bits (849), Expect = 1e-90
Identities = 217/675 (32%), Positives = 323/675 (47%), Gaps = 76/675 (11%)
Query: 65 DSSGHQELKQGPNPL-APSPSAPSTSAGLGDCNHRVDLSKTFSVSSALAMLQERRCLYVV 123
++S QEL++ P +P PS PS + + R F S +CL
Sbjct: 42 ENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRC 101
Query: 124 LTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVV 183
T FL+ C L Q ++V+G ++ I+T+E+RY +KSS +GL+ S +DI ++ +
Sbjct: 102 NTPGG-FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSL 160
Query: 184 FVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNST 243
FVS+FG RG +P WLA +I GA +F+LP F S Y++ S D NST
Sbjct: 161 FVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKL----GSLFEDTCVTTRNST 216
Query: 244 ATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLA 303
+C + ++++YV FI Q+L+G G TP+YTLG +LDD+V SSLY+
Sbjct: 217 ------SCTSSTSSLSNYLYV--FILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIG 268
Query: 304 IMYVMGALGPAVGYLLGGLLIGFYVDPR--NPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
Y M LGPA+GY+LGG L+ Y+D + ++DPR++G WW GFLL I + +
Sbjct: 269 TGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSL 328
Query: 362 IFPMFTFPKKLPPRHKKKKKK-------------KFSVDAVSDDDVLKEKSNN------- 401
I P FPK LP + + K KF LK N
Sbjct: 329 IIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALKNLMKNAVFMCLV 388
Query: 402 -SEQADKKVS-----------------SMGFGKDVRGVIIVPSAGVGIVLGGYIIKKLKL 443
S ++ ++ + F + G +++P A +G +LGG+++ K ++
Sbjct: 389 LSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRM 448
Query: 444 GARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVN 503
+ + K A+ SGV+L CE+ G++ Y L NL CN N
Sbjct: 449 TCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGEL----GNLIAPCNAN 504
Query: 504 CGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVGQR 563
C C Y PVCG DG+ YF+PC AGC N + Y C+C++ + IT
Sbjct: 505 CNCSRSYYYPVCG-DGVQYFSPCFAGCSNP-VAHRKPKVYYNCSCIERKTEITS------ 556
Query: 564 SQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTLRSVE 623
+T+ E A +GKC+ C L FL FIV T A + LR V
Sbjct: 557 ------TAETFGFE---AKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVN 607
Query: 624 DEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFV 682
+R ALG+QF++LR L IP PI FG ID+TC+LW +CG++G+CW Y+ +
Sbjct: 608 HRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHM 667
Query: 683 YFGLAAGLKFVGFIF 697
++ K + F
Sbjct: 668 LVAISVTCKVITMFF 682
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 331 bits (848), Expect = 2e-90
Identities = 219/691 (31%), Positives = 340/691 (49%), Gaps = 114/691 (16%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FLV C L Q V YL SV+TT+ERR++L+S++ G++ S F+IGNL +++FVSY
Sbjct: 40 KIFLVSECALMLAQGT-VGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSY 98
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQ--ELNASAPNDGLCQGGNSTAT 245
FG RG RP + GG+++A GA L ALP F++ Y+ + E+ A +C S
Sbjct: 99 FGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGD 158
Query: 246 LEPP---ACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYL 302
P C + N ++ L I AQ+L+G+G+TP+ LG +Y+DD+V++++SSLY+
Sbjct: 159 EGPDPDLICRNRTATNMMYL---LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYI 215
Query: 303 AIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAM 358
I++ M GPA G++LG YVD + + + +DPR+IG WW GFLLC +
Sbjct: 216 GILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALL 275
Query: 359 FLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSE--------------- 403
F MF FP+ LPP + + + ++ +S+ + + K +N
Sbjct: 276 FFSSLLMFGFPQSLPPHSEPAMESEQAM--LSEREYERPKPSNGVLRHPLEPDSSASCFQ 333
Query: 404 --QADKKVSSMGFGKDVRGVIIVPS-------AGVGIVLGGY------------------ 436
+ KV+ V II+ + AG LG Y
Sbjct: 334 QLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGM 393
Query: 437 ---------------IIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINI 481
++KKL L A + ++AM+ + VS C+ + +GC++ + G+ +
Sbjct: 394 TAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTV 453
Query: 482 PY--TTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTG 539
PY +T P + + CN NC C+ + PVCG+DGITY + C AGC NS NL
Sbjct: 454 PYGNSTAPGSAL---DPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGC-NSTNL--- 506
Query: 540 IRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT-C-NTLIPFL 597
T C C + T EN V GKC C + FL
Sbjct: 507 ----TGCAC----------------------LTTVPAENATVVPGKCPSPGCQEAFLTFL 540
Query: 598 VFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTT 657
+ I + I A AQ ++I+ +R+V E + +ALG+ F+LLR L +IP P+ FGA ID+T
Sbjct: 541 CVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDST 600
Query: 658 CMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQRRRQ 717
C+ W CG QG+C Y+ +R++Y +A LK FI W + +++ + +
Sbjct: 601 CLFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCL--RKNYKRYIKN 658
Query: 718 REFPLSTVSERVGHPDNARTRSCPAFSTQGE 748
E LST +E + D ++CP + E
Sbjct: 659 HEGGLSTSTE---YQDIETEKTCPESHSPSE 686
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 328 bits (842), Expect = 9e-90
Identities = 210/649 (32%), Positives = 322/649 (49%), Gaps = 109/649 (16%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FLV C L Q V YL SV+TT+ERR++L+S++ G++ S F+IGNL +++FVSY
Sbjct: 40 KIFLVSECALMLAQGT-VGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSY 98
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQ--ELNASAPNDGLCQGGNSTAT 245
FG RG RP + GG+++A GA L ALP F++ Y+ + E+ A +C S
Sbjct: 99 FGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGD 158
Query: 246 LEPP---ACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYL 302
P C + N ++ L I AQ+L+G+G+TP+ LG +Y+DD+V++++SSLY+
Sbjct: 159 EGPDPDLICRNRTATNMMYL---LLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYI 215
Query: 303 AIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAM 358
I++ M GPA G++LG YVD + + + +DPR+IG WW GFLLC +
Sbjct: 216 GILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALL 275
Query: 359 FLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSE--------------- 403
F MF FP+ LPP + + + ++ +S+ + + K +N
Sbjct: 276 FFSSLLMFGFPQSLPPHSEPAMESEQAM--LSEREYERPKPSNGVLRHPLEPDSSASCFQ 333
Query: 404 --QADKKVSSMGFGKDVRGVIIVPS-------AGVGIVLGGY------------------ 436
+ KV+ V II+ + AG LG Y
Sbjct: 334 QLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGM 393
Query: 437 ---------------IIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINI 481
++KKL L A + ++AM+ + VS C+ + +GC++ + G+ +
Sbjct: 394 TAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTV 453
Query: 482 PY--TTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTG 539
PY +T P + + CN NC C+ + PVCG+DGITY + C AGC NS NL
Sbjct: 454 PYGNSTAPGSAL---DPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGC-NSTNL--- 506
Query: 540 IRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT-C-NTLIPFL 597
T C C + T EN V GKC C + FL
Sbjct: 507 ----TGCAC----------------------LTTVPAENATVVPGKCPSPGCQEAFLTFL 540
Query: 598 VFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTT 657
+ I + I A AQ ++I+ +R+V E + +ALG+ F+LLR L +IP P+ FGA ID+T
Sbjct: 541 CVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDST 600
Query: 658 CMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 706
C+ W CG QG+C Y+ +R++Y +A LK FI W ++
Sbjct: 601 CLFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLR 649
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 300 bits (769), Expect = 3e-81
Identities = 210/685 (30%), Positives = 327/685 (47%), Gaps = 112/685 (16%)
Query: 101 LSKTFSVSSALAMLQERRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSV-ITTIERR 159
L+KT + S++ + RRC + FL + F +AL G + + IT IERR
Sbjct: 7 LNKT-AESASSEKKKTRRC-----NGFKMFLAALSFSYIAKAL--GGIIMKISITQIERR 58
Query: 160 YSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFIS 219
+ + SS +GL+ F+IGNL+V+VFVSYFG + RP + +G LL+ G+ L +LPHF
Sbjct: 59 FDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFM 118
Query: 220 PPYQIQE-------------LNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVAL 266
Y+ + L+ N L G S +E C K+SG ++ W+YV +
Sbjct: 119 GYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKD-CVKESG-SHMWIYVFM 176
Query: 267 FICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGF 326
+L G+G TPI LG +Y+DD K+ +SSLYL + +G +GP +G+ LG L
Sbjct: 177 ---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKM 233
Query: 327 YVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKK 382
YVD + + + D R++G WW GFL+ + + P F PK P + +K++K
Sbjct: 234 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKI 292
Query: 383 KFSVDAVSDDDVLKEKSNNSEQADKKVSSM-GFGKDVR---------------------- 419
S+ + +D + +N + Q ++ GF + ++
Sbjct: 293 SLSLHVLKTNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSF 352
Query: 420 --------------------------GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAM 453
G+I +P+ G+ LGG+IIKK KL AK +
Sbjct: 353 IGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSF 412
Query: 454 ICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEP 513
+ S +S L F + CES ++ G+ + Y S+ CN C C ++EP
Sbjct: 413 LTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEP 472
Query: 514 VCGSDGITYFNPCLAGCVNSGNLSTGIRNYT---ECTCVQSRQVITPPTVGQRSQLRVVI 570
VCG++GITY +PCLAGC + S+GI+ +T C+CV+
Sbjct: 473 VCGNNGITYLSPCLAGCKS----SSGIKKHTVFYNCSCVE-------------------- 508
Query: 571 VKTYLNENGYAVSGKCKRTCNTLIPFLVFL---FIVTFITACAQPSAIIVTLRSVEDEER 627
V N N A G+C R F +++ I + +A + I++T++ V+ E +
Sbjct: 509 VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELK 568
Query: 628 PFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFVYFGL 686
A+G Q +++RTL I PIYFGA+ID TCM W CG QG+C YN F VY GL
Sbjct: 569 ALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGL 628
Query: 687 AAGLKFVGFIFIFLAWYSIKYKEDG 711
+ L+F + + +++K K G
Sbjct: 629 SIALRFPALVLYIVFIFAMKKKFQG 653
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 292 bits (748), Expect = 7e-79
Identities = 198/653 (30%), Positives = 314/653 (48%), Gaps = 92/653 (14%)
Query: 118 RCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIG 177
RC V + + F++C L Q L+ S Y S +TTIE+R+ L SS SGL+ S +I
Sbjct: 22 RCARSVFGNIKVFVLCQGLLQLCQ-LLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEIS 80
Query: 178 NLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQ---IQELNASAPND 234
N ++++FVSYFG R RP + +GGL +A GA + LPHF+S PYQ N S
Sbjct: 81 NAILIIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGNNSRLQA 140
Query: 235 GLCQGGNSTATLEPPACPKDSGG-----NNHWVYVALFICAQILIGMGSTPIYTLGPTYL 289
LCQ L P C + ++ W L + AQ+L G+G+ PI G +Y+
Sbjct: 141 ELCQ--KHWQDLPPSKCHSTTQNPQKETSSMW---GLMVVAQLLAGIGTVPIQPFGISYV 195
Query: 290 DDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIG 345
DD + NS LY++I++ + GPA GYLLG +++ +VD V+L DPR+IG
Sbjct: 196 DDFSEPSNSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGRVNTAAVNLVPGDPRWIG 255
Query: 346 NWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKK-------------KKKKKFSVDAVSDD 392
WW G L+ + + L FP F FP+ +P K+ K + VD +
Sbjct: 256 AWWLGLLISSALLVLTSFPFFFFPRAMPIGAKRAPATADEARKLEEAKSRGSLVDFIKRF 315
Query: 393 D---------------VLKEKSNNSEQADKKV-----------SSMGFGKDVRGVIIVPS 426
VL + + +S A +S + + G + +P+
Sbjct: 316 PCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFLNKFLEKQYGTSAAYANFLIGAVNLPA 375
Query: 427 AGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTG 486
A +G++ GG ++K+ + ++A +S++ LF +GC + + + P T+
Sbjct: 376 AALGMLFGGILMKRFVFSLQAIPRIATTIITISMILCVPLFFMGCSTPTVAEVYPPSTS- 434
Query: 487 PSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGC--VNSGNLSTGIRNYT 544
S P + +C +C C + PVCG +GI Y +PC AGC +N + ++ Y
Sbjct: 435 -SSIHPQ---SPACRRDCSCPDSIFHPVCGDNGIEYLSPCHAGCSNINMSSATSKQLIYL 490
Query: 545 ECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTC-NTLIPFLVFLFIV 603
C+CV T G S A +G C C + L+P + + V
Sbjct: 491 NCSCV---------TGGSAS----------------AKTGSCPVPCAHFLLPAIFLISFV 525
Query: 604 TFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQ 663
+ I + ++ LR V EE+ FA+G+QF+L+R LA++P+P +G ID +C+ W
Sbjct: 526 SLIACISHNPLYMMVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLTIDHSCIRWNS 585
Query: 664 EC-GVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFI-FLAWYSIKYKEDGLQR 714
C G +G+C Y+ + R Y GL G K +G + + F++W K KE +Q+
Sbjct: 586 LCLGRRGACAYYDNDALRDRYLGLQMGYKALGMLLLCFISWRVKKNKEYNVQK 638
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 286 bits (732), Expect = 5e-77
Identities = 199/649 (30%), Positives = 307/649 (47%), Gaps = 111/649 (17%)
Query: 137 LTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPL 196
L+FI + + + S I IERR+ + SS G + F+IGNL+V+VFVSYFG + RP
Sbjct: 36 LSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPK 95
Query: 197 WLAVGGLLIAFGAALFALPHFISPPYQI-QELNASAPNDGLCQGGNSTATLEP------- 248
+ +G ++ G L ALPHF Y+ +E N ++ NST+TL
Sbjct: 96 LIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSSE-------NSTSTLSTCLINQIL 148
Query: 249 -----------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKEN 297
C K+SG + W+YV + +L G+G TPI LG +Y+DD K+ +
Sbjct: 149 SLNRASPEIVGKGCLKESG-SYMWIYVFM---GNMLRGIGETPIVPLGLSYIDDFAKEGH 204
Query: 298 SSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLL 353
SSLYL I+ + +GP +G+ LG L YVD + + + D R++G WW FL+
Sbjct: 205 SSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLV 264
Query: 354 CAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSM- 412
+ + P F P+ P + +K++K S+ + +D + +N + Q ++
Sbjct: 265 SGLFSIISSIPFFFLPQT-PNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNITKNVT 323
Query: 413 GFGKDVR------------------------------------------------GVIIV 424
GF + + GVI +
Sbjct: 324 GFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITI 383
Query: 425 PSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYT 484
P G+ LGGYIIKK KL AK + + +SL + F + CE+ ++ G+ + Y
Sbjct: 384 PIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYD 443
Query: 485 TGPSLTMPHRNLTGS-CNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNY 543
+T HR++ S CN +C C ++EPVCG++GITY +PCLAGC +S I Y
Sbjct: 444 GNNPVTS-HRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFY 502
Query: 544 TECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTLIPFLVFLF 601
C+C++ V N N A G+C R C F V +
Sbjct: 503 -NCSCLE--------------------VTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQ 541
Query: 602 IVT-FITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCML 660
++ F +A S +++ ++ V+ E + ALG +++R L I PIYFGA+IDTTC+
Sbjct: 542 VLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIK 601
Query: 661 WQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYK 708
W CG +GSC YN TSF VY GL++ L+ + + Y++K K
Sbjct: 602 WSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKK 650
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 283 bits (725), Expect = 3e-76
Identities = 192/658 (29%), Positives = 301/658 (45%), Gaps = 114/658 (17%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
Query: 248 P----------------------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLG 285
P C D+ ++ W+YV L +L G+G TPI LG
Sbjct: 153 PCLLESSSQLPVSVMEKSKSKISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLG 208
Query: 286 PTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDP 341
YLDD ++N++ Y+ + + +GP G+LLG L YVD + + + DP
Sbjct: 209 IAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDP 268
Query: 342 RFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVL 395
+++G WW G+L+ I L P + PK LP ++ +K KF +D +D
Sbjct: 269 QWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTP 328
Query: 396 K-EKSNNSEQADKKVSSMG--FGKDVR--------------------------------- 419
+ E + E A + S+ FG V
Sbjct: 329 QGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSS 388
Query: 420 -------GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCE 472
G+I +P+ +GI GG ++KK ++ +AKL + S L F +LF +GCE
Sbjct: 389 SRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCE 448
Query: 473 SINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVN 532
+ ++ G+ + Y ++ R L CN C C ++EP+CG +GITY + CLAGC
Sbjct: 449 NSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQT 508
Query: 533 SGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C 590
S I Y CTCV + + N + G+C++ C
Sbjct: 509 SNRSGKNIIFY-NCTCVG--------------------IAASKSGNSSGIVGRCQKDNGC 547
Query: 591 -NTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIY 649
+ FLV I ++ + I+ LR ++ + + FALG+ + +R LA IP P+Y
Sbjct: 548 PQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVY 607
Query: 650 FGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 706
FG +IDT+C+ W + CG +GSC Y+ FR +Y GL L V + + +K
Sbjct: 608 FGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILK 665
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 283 bits (723), Expect = 6e-76
Identities = 186/643 (28%), Positives = 304/643 (47%), Gaps = 116/643 (18%)
Query: 128 RCFLVCMCFLTFIQALMVS-----GYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
RC FL I VS Y++S++T IER++++ +S G + F+IGNL+++
Sbjct: 14 RCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLI 73
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLC 237
+FVSYFG + RP+ + +G +++ G L +LPHF+ Y+ + N S+ N LC
Sbjct: 74 IFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLC 132
Query: 238 QGGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVK 294
+ T +P C K+ + WVYV + I+ GMG TPI LG +Y++D K
Sbjct: 133 MENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAK 188
Query: 295 KENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSG 350
ENS LY+ ++ +GP +G LL YVD + + + D R++G WW G
Sbjct: 189 FENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFG 248
Query: 351 FLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVS 410
FL+CA L P F P LP K+ +A D++K ++ + ++ + K
Sbjct: 249 FLICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKE 297
Query: 411 SMGFGKD----------------------------------------------------V 418
G KD +
Sbjct: 298 KYGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFL 357
Query: 419 RGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGG 478
G+ +P +G ++GG I+KK K+ +++A + S + L + F++ CE+ ++ G
Sbjct: 358 MGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVG 417
Query: 479 INIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLST 538
IN Y P ++ CNV+C C ++PVCG++G++Y + CLAGC S + T
Sbjct: 418 INTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS--IGT 475
Query: 539 GIRN-YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTLIP 595
GI + C+C+Q+ + N AV G C + C+ ++
Sbjct: 476 GINMVFQNCSCIQT------------------------SGNSSAVLGLCDKGPDCSLMLQ 511
Query: 596 -FLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVI 654
FL+ + +FI + A +V LR ++ EE+ +G+ R A IP PIYFGA++
Sbjct: 512 YFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALM 571
Query: 655 DTTCMLW-QQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 696
D+TC+ W +CG G+C Y+ T+FR++Y GL A L+ F+
Sbjct: 572 DSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFV 614
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 283 bits (723), Expect = 6e-76
Identities = 186/643 (28%), Positives = 304/643 (47%), Gaps = 116/643 (18%)
Query: 128 RCFLVCMCFLTFIQALMVS-----GYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
RC FL I VS Y++S++T IER++++ +S G + F+IGNL+++
Sbjct: 14 RCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLI 73
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQEL-----NASAPNDGLC 237
+FVSYFG + RP+ + +G +++ G L +LPHF+ Y+ + N S+ N LC
Sbjct: 74 IFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGNLSS-NSFLC 132
Query: 238 QGGNSTA---TLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVK 294
+ T +P C K+ + WVYV + I+ GMG TPI LG +Y++D K
Sbjct: 133 MENGTQILRPTQDPSECTKEVK-SLMWVYV---LVGNIVRGMGETPILPLGISYIEDFAK 188
Query: 295 KENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVDP----RNPVHLDQNDPRFIGNWWSG 350
ENS LY+ ++ +GP +G LL YVD + + + D R++G WW G
Sbjct: 189 FENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFG 248
Query: 351 FLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVS 410
FL+CA L P F P LP K+ +A D++K ++ + ++ + K
Sbjct: 249 FLICAGVNVLTAIPFFFLPNTLP-------KEGLETNA----DIIKNENEDKQKEEVKKE 297
Query: 411 SMGFGKD----------------------------------------------------V 418
G KD +
Sbjct: 298 KYGITKDFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFL 357
Query: 419 RGVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGG 478
G+ +P +G ++GG I+KK K+ +++A + S + L + F++ CE+ ++ G
Sbjct: 358 MGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVG 417
Query: 479 INIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLST 538
IN Y P ++ CNV+C C ++PVCG++G++Y + CLAGC S + T
Sbjct: 418 INTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETS--IGT 475
Query: 539 GIRN-YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKR--TCNTLIP 595
GI + C+C+Q+ + N AV G C + C+ ++
Sbjct: 476 GINMVFQNCSCIQT------------------------SGNSSAVLGLCDKGPDCSLMLQ 511
Query: 596 -FLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVI 654
FL+ + +FI + A +V LR ++ EE+ +G+ R A IP PIYFGA++
Sbjct: 512 YFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALM 571
Query: 655 DTTCMLW-QQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFI 696
D+TC+ W +CG G+C Y+ T+FR++Y GL A L+ F+
Sbjct: 572 DSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFV 614
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 275 bits (704), Expect = 9e-74
Identities = 186/633 (29%), Positives = 292/633 (46%), Gaps = 114/633 (18%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
Query: 248 P----------------------PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLG 285
P C D+ ++ W+YV L +L G+G TPI LG
Sbjct: 153 PCLLESSSQLPVSVMEKSKSKISNECEVDT-SSSMWIYVFL---GNLLRGIGETPIQPLG 208
Query: 286 PTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDP 341
YLDD ++N++ Y+ + + +GP G+LLG L YVD + + + DP
Sbjct: 209 IAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDP 268
Query: 342 RFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVL 395
+++G WW G+L+ I L P + PK LP ++ +K KF +D +D
Sbjct: 269 QWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTP 328
Query: 396 K-EKSNNSEQADKKVSSMG--FGKDVR--------------------------------- 419
+ E + E A + S+ FG V
Sbjct: 329 QGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSS 388
Query: 420 -------GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCE 472
G+I +P+ +GI GG ++KK ++ +AKL + S L F +LF +GCE
Sbjct: 389 SRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCE 448
Query: 473 SINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVN 532
+ ++ G+ + Y ++ R L CN C C ++EP+CG +GITY + CLAGC
Sbjct: 449 NSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQT 508
Query: 533 SGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C 590
S I Y CTCV + + N + G+C++ C
Sbjct: 509 SNRSGKNIIFY-NCTCVG--------------------IAASKSGNSSGIVGRCQKDNGC 547
Query: 591 -NTLIPFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIY 649
+ FLV I ++ + I+ LR ++ + + FALG+ + +R LA IP P+Y
Sbjct: 548 PQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVY 607
Query: 650 FGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRF 681
FG +IDT+C+ W + CG +GSC Y+ FR+
Sbjct: 608 FGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRY 640
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 271 bits (693), Expect = 2e-72
Identities = 190/629 (30%), Positives = 296/629 (47%), Gaps = 99/629 (15%)
Query: 154 TTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFA 213
T IERR+ + SS GL+ F+IGNL V+VFVSYFG + RP + +G L+ G+ L A
Sbjct: 6 TQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMA 65
Query: 214 LPHFISPPYQIQELNASAPNDGLCQG------------GNSTATLEPPACPKDSGGNNHW 261
LPHF Y+ + P++ + + + C K+SG ++ W
Sbjct: 66 LPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG-SHMW 124
Query: 262 VYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGG 321
+YV + +L G+G TPI LG +Y+DD K+ +SSLYL + VMG G ++LG
Sbjct: 125 IYVFM---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGS 181
Query: 322 LLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHK 377
L YVD + + + D R++G WW GFL+ I + P F P P + +
Sbjct: 182 LFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLN-PNKPQ 240
Query: 378 KKKKKKFSVDAVSDDDVLKEKSNNSEQADKKVSSM-GFGKDVR----------------- 419
K++K + + +D + +N + + ++ GF + ++
Sbjct: 241 KERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLL 300
Query: 420 -------------------------------GVIIVPSAGVGIVLGGYIIKKLKLGARES 448
GV+ +P+ +G+ GGYIIKK KL
Sbjct: 301 HMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL 360
Query: 449 AKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGS-CNVNCGCK 507
AKLA + V LL F + CES ++ G+ + Y G S H ++ S CN C C
Sbjct: 361 AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYD-GNSPVRSHVDVPLSYCNSECNCD 419
Query: 508 IHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVGQRSQLR 567
++EPVCG++GITY +PCLAGC +S I Y C+CV+ +G +
Sbjct: 420 ESQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFY-NCSCVE--------VIGLQ---- 466
Query: 568 VVIVKTYLNENGYAVSGKCKR----TCNTLIPFLVFLFIVTFITACAQPSAIIVTLRSVE 623
N+N A G+C R T + + F++ + + F+ A S ++ +R V+
Sbjct: 467 --------NKNYSAHLGECPRDDACTRKSYVYFVIQV-LDAFLCAVGLTSYSVLVIRIVQ 517
Query: 624 DEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFV 682
E + A+G +++R+L I PIYFGA+IDTTCM W CG +G+C YN T
Sbjct: 518 PELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRA 577
Query: 683 YFGLAAGLKFVGFIFIFLAWYSIKYKEDG 711
+FGL L F + + + + ++ K G
Sbjct: 578 FFGLKVALIFPVLVLLTVFIFVVRKKSHG 606
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 248 bits (633), Expect = 2e-65
Identities = 177/636 (27%), Positives = 280/636 (44%), Gaps = 119/636 (18%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
+ FL + F+ F +AL GYL S IT IERR+ + SS G++ F+IGNL+V+ FVSY
Sbjct: 43 KVFLCALSFVYFAKAL-AEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSY 101
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLE 247
FG + RP + G +++ G L A+P F Y+ + + S+ NST ++
Sbjct: 102 FGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSS---------NSTLSIS 152
Query: 248 PPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYV 307
P C +L P+ + +K S + +
Sbjct: 153 P--------------------C--LLESSSQLPVSVM---------EKSKSKISNGCVQT 181
Query: 308 MGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIF 363
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 182 VAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAV 241
Query: 364 PMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLK-EKSNNSEQADKKVSSMG--F 414
P + PK LP ++ +K KF +D +D + E + E A + S+ F
Sbjct: 242 PFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKNLF 301
Query: 415 GKDVR----------------------------------------GVIIVPSAGVGIVLG 434
G V G+I +P+ +GI G
Sbjct: 302 GNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSG 361
Query: 435 GYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHR 494
G ++KK ++ +AKL + S L F +LF +GCE+ ++ G+ + Y ++ R
Sbjct: 362 GIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHER 421
Query: 495 NLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQV 554
L CN C C ++EP+CG +GITY + CLAGC S I Y CTCV
Sbjct: 422 ALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFY-NCTCVG---- 476
Query: 555 ITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C-NTLIPFLVFLFIVTFITACAQ 611
+ + N + G+C++ C + FLV I ++ +
Sbjct: 477 ----------------IAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGG 520
Query: 612 PSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGS 670
I+ LR ++ + + FALG+ + +R LA IP P+YFG +IDT+C+ W + CG +GS
Sbjct: 521 IPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGS 580
Query: 671 CWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIK 706
C Y+ FR +Y GL L V + + +K
Sbjct: 581 CRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILK 616
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 226 bits (575), Expect = 8e-59
Identities = 162/626 (25%), Positives = 271/626 (43%), Gaps = 86/626 (13%)
Query: 128 RCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSY 187
RCF++ C L Q + V G + I ++ Y LK+ E L +DI + +V +F+++
Sbjct: 106 RCFMIFYCILLICQGV-VFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIFIAF 164
Query: 188 FGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPN--DGLCQGGNSTAT 245
+G R ++ +W LI G+ L A P I E N + + +C+
Sbjct: 165 YGDR-KKVIWFVASSFLIGLGSLLCAFP-------SINEENKQSKVGIEDICE------E 210
Query: 246 LEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
++ + + SG + Y++ FI Q + G+ P+Y LG T++D+NV ++ +YL I
Sbjct: 211 IKVVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDENVATHSAGIYLGIA 270
Query: 306 YVMGALGPAVGYLLGGLLIGFYVDPRNPVHLDQND--PRFIGNWWSGFLLCAIAMFLVIF 363
+G A+GY+LG L+ + + + N+ P ++ WW FL A+ + +
Sbjct: 271 ECTSMIGYALGYVLGAPLVKVPENTTSATNTTVNNGSPEWLWTWWINFLFAAVVAWCTLI 330
Query: 364 PMFTFPKKLPP----RHKKKKKKKFSVDAVSDDDVLKEKSNNSE---------------- 403
P+ FP +P + +K+K+ F + D LK +N +
Sbjct: 331 PLSCFPNNMPGSTRIKARKRKQLHFFDSRLKD---LKLGTNIKDLCAALWILMKNPVLIC 387
Query: 404 ----QADKKVSSMGFGK------------------DVRGVIIVPSAGVGIVLGGYIIKKL 441
+A + + +G + + G++++P +G +LGG I+ L
Sbjct: 388 LALSKATEYLVIIGASEFLPIYLENQFILTPTVATTLAGLVLIPGGALGQLLGGVIVSTL 447
Query: 442 KLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCN 501
++ + + M+ S +SL+ + V C + GIN Y L NLT CN
Sbjct: 448 EMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAGINEDYDGTGKLG----NLTAPCN 503
Query: 502 VNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSRQVITPPTVG 561
C C Y +CG D I YF+PC AGC S + Y C+C++ +IT G
Sbjct: 504 EKCRCSSSIYSSICGRDDIEYFSPCFAGCTYS-KAQNQKKMYYNCSCIK-EGLITADAEG 561
Query: 562 QRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFLFIVTFITACAQPSAIIVTLRS 621
R GKC C L F+ F+F + + ++ R
Sbjct: 562 DFIDAR---------------PGKCDAKCYKLPLFIAFIFSTLIFSGFSGVPIVLAMTRV 606
Query: 622 VEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFR 680
V D+ R ALG+ +V+LR IP P F +T+C+L +CG G CW YN T
Sbjct: 607 VPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRCWIYNKTKMA 666
Query: 681 FVYFGLAAGLKFVGFIFIFLAWYSIK 706
F+ G+ K IF +A++ K
Sbjct: 667 FLLVGICFLCKLCTIIFTTIAFFIYK 692
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 214 bits (544), Expect = 3e-55
Identities = 152/553 (27%), Positives = 242/553 (43%), Gaps = 113/553 (20%)
Query: 208 GAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEP------------------- 248
G L A+P F Y+ + + S+ NST ++ P
Sbjct: 4 GTLLIAMPQFFMEQYKYERYSPSS---------NSTLSISPCLLESSSQLPVSVMEKSKS 54
Query: 249 ---PACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIM 305
C D+ ++ W+YV L +L G+G TPI LG YLDD ++N++ Y+ +
Sbjct: 55 KISNECEVDTS-SSMWIYVFL---GNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCV 110
Query: 306 YVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLV 361
+ +GP G+LLG L YVD + + + DP+++G WW G+L+ I L
Sbjct: 111 QTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLA 170
Query: 362 IFPMFTFPKKLPPRHKKK------KKKKFSVDAVSDDDVLK-EKSNNSEQADKKVSSMG- 413
P + PK LP ++ +K KF +D +D + E + E A + S+
Sbjct: 171 AVPFWYLPKSLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGENAKIMEMARDFLPSLKN 230
Query: 414 -FGKDVR----------------------------------------GVIIVPSAGVGIV 432
FG V G+I +P+ +GI
Sbjct: 231 LFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIF 290
Query: 433 LGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMP 492
GG ++KK ++ +AKL + S L F +LF +GCE+ ++ G+ + Y ++
Sbjct: 291 SGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYH 350
Query: 493 HRNLTGSCNVNCGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTCVQSR 552
R L CN C C ++EP+CG +GITY + CLAGC S I Y CTCV
Sbjct: 351 ERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFY-NCTCVG-- 407
Query: 553 QVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRT--C-NTLIPFLVFLFIVTFITAC 609
+ + N + G+C++ C + FLV I ++ +
Sbjct: 408 ------------------IAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSL 449
Query: 610 AQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQ 668
I+ LR ++ + + FALG+ + +R LA IP P+YFG +IDT+C+ W + CG +
Sbjct: 450 GGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSR 509
Query: 669 GSCWEYNVTSFRF 681
GSC Y+ FR+
Sbjct: 510 GSCRLYDSNVFRY 522
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 191 bits (484), Expect = 3e-48
Identities = 109/296 (36%), Positives = 162/296 (54%), Gaps = 19/296 (6%)
Query: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
V + + F++C L Q LM+SGYL S I+T+E+R+ L S SGLL S ++GN ++
Sbjct: 22 VFHNIKLFVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 80
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
VFVSYFG R RP + G +L+A L LPHFIS PY+ ++P D + Q +
Sbjct: 81 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN---TSPED-MPQDFKA 136
Query: 243 TATLEPPACPKDSGGN---------NHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNV 293
+ L + P + N H V + AQ L+G+G PI G +Y+DD
Sbjct: 137 SLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFA 196
Query: 294 KKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWS 349
NS LYL I++ + +GP + + LG L++ YVD P + L DPR++G WW
Sbjct: 197 HNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWL 256
Query: 350 GFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQA 405
GFL+ A A+ L P F FPK++ P+ K++ + + V AV+D K K + S+Q+
Sbjct: 257 GFLIAAGAVALAAIPYFFFPKEM-PKEKRELQFRRKVLAVTDSPARKGKDSPSKQS 311
Score = 135 bits (339), Expect = 2e-31
Identities = 89/308 (28%), Positives = 140/308 (45%), Gaps = 38/308 (12%)
Query: 420 GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGI 479
G + PS VGIV+GG ++K+L LG L ++ + L LF +GC S + GI
Sbjct: 392 GCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGI 451
Query: 480 NIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITYFNPCLAGCVNSGNLST 538
+ P L L+ SC C C + + PVC S + Y PC AGC +S +
Sbjct: 452 THQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGC-SSWVVQD 505
Query: 539 GIRN----YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLI 594
+ N YT C+CV E ++G C TC+ L+
Sbjct: 506 ALDNSQVFYTNCSCVV--------------------------EGNPVLAGSCDSTCSHLV 539
Query: 595 -PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAV 653
PFL+ + + + + + ++ LR V+ E++ A+G+QF+ LR LA++P+P+ G+
Sbjct: 540 VPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSA 599
Query: 654 IDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQ 713
IDTTC+ W CG + C YN R + GL K I L ++ ++ +
Sbjct: 600 IDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEAR 659
Query: 714 RRRQREFP 721
+ R P
Sbjct: 660 TKESRSSP 667
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 191 bits (484), Expect = 3e-48
Identities = 109/296 (36%), Positives = 162/296 (54%), Gaps = 19/296 (6%)
Query: 123 VLTDSRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVV 182
V + + F++C L Q LM+SGYL S I+T+E+R+ L S SGLL S ++GN ++
Sbjct: 44 VFHNIKLFVLCHSLLQLAQ-LMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALI 102
Query: 183 VFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNS 242
VFVSYFG R RP + G +L+A L LPHFIS PY+ ++P D + Q +
Sbjct: 103 VFVSYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDN---TSPED-MPQDFKA 158
Query: 243 TATLEPPACPKDSGGN---------NHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNV 293
+ L + P + N H V + AQ L+G+G PI G +Y+DD
Sbjct: 159 SLCLPTTSAPASAPSNGNCSSYTETQHLSVVGIMFVAQTLLGVGGVPIQPFGISYIDDFA 218
Query: 294 KKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFIGNWWS 349
NS LYL I++ + +GP + + LG L++ YVD P + L DPR++G WW
Sbjct: 219 HNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWL 278
Query: 350 GFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQA 405
GFL+ A A+ L P F FPK++ P+ K++ + + V AV+D K K + S+Q+
Sbjct: 279 GFLIAAGAVALAAIPYFFFPKEM-PKEKRELQFRRKVLAVTDSPARKGKDSPSKQS 333
Score = 135 bits (339), Expect = 2e-31
Identities = 89/308 (28%), Positives = 140/308 (45%), Gaps = 38/308 (12%)
Query: 420 GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGI 479
G + PS VGIV+GG ++K+L LG L ++ + L LF +GC S + GI
Sbjct: 414 GCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGI 473
Query: 480 NIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITYFNPCLAGCVNSGNLST 538
+ P L L+ SC C C + + PVC S + Y PC AGC +S +
Sbjct: 474 THQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGC-SSWVVQD 527
Query: 539 GIRN----YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLI 594
+ N YT C+CV E ++G C TC+ L+
Sbjct: 528 ALDNSQVFYTNCSCVV--------------------------EGNPVLAGSCDSTCSHLV 561
Query: 595 -PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAV 653
PFL+ + + + + + ++ LR V+ E++ A+G+QF+ LR LA++P+P+ G+
Sbjct: 562 VPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSA 621
Query: 654 IDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQ 713
IDTTC+ W CG + C YN R + GL K I L ++ ++ +
Sbjct: 622 IDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEAR 681
Query: 714 RRRQREFP 721
+ R P
Sbjct: 682 TKESRSSP 689
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 135 bits (339), Expect = 2e-31
Identities = 89/308 (28%), Positives = 140/308 (45%), Gaps = 38/308 (12%)
Query: 420 GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGCESINLGGI 479
G + PS VGIV+GG ++K+L LG L ++ + L LF +GC S + GI
Sbjct: 270 GCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGI 329
Query: 480 NIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEPVCG-SDGITYFNPCLAGCVNSGNLST 538
+ P L L+ SC C C + + PVC S + Y PC AGC +S +
Sbjct: 330 THQTSAHPGL-----ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGC-SSWVVQD 383
Query: 539 GIRN----YTECTCVQSRQVITPPTVGQRSQLRVVIVKTYLNENGYAVSGKCKRTCNTLI 594
+ N YT C+CV E ++G C TC+ L+
Sbjct: 384 ALDNSQVFYTNCSCVV--------------------------EGNPVLAGSCDSTCSHLV 417
Query: 595 -PFLVFLFIVTFITACAQPSAIIVTLRSVEDEERPFALGMQFVLLRTLAYIPTPIYFGAV 653
PFL+ + + + + + ++ LR V+ E++ A+G+QF+ LR LA++P+P+ G+
Sbjct: 418 VPFLLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSA 477
Query: 654 IDTTCMLWQQECGVQGSCWEYNVTSFRFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDGLQ 713
IDTTC+ W CG + C YN R + GL K I L ++ ++ +
Sbjct: 478 IDTTCVHWALSCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEAR 537
Query: 714 RRRQREFP 721
+ R P
Sbjct: 538 TKESRSSP 545
Score = 110 bits (276), Expect = 4e-24
Identities = 63/181 (34%), Positives = 94/181 (51%), Gaps = 20/181 (11%)
Query: 229 ASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTY 288
ASAP++G C T H V + AQ L+G+G PI G +Y
Sbjct: 25 ASAPSNGNCSSYTET---------------QHLSVVGIMFVAQTLLGVGGVPIQPFGISY 69
Query: 289 LDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGFYVD----PRNPVHLDQNDPRFI 344
+DD NS LYL I++ + +GP + + LG L++ YVD P + L DPR++
Sbjct: 70 IDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWV 129
Query: 345 GNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKKKFSVDAVSDDDVLKEKSNNSEQ 404
G WW GFL+ A A+ L P F FPK++ P+ K++ + + V AV+D K K + S+Q
Sbjct: 130 GAWWLGFLIAAGAVALAAIPYFFFPKEM-PKEKRELQFRRKVLAVTDSPARKGKDSPSKQ 188
Query: 405 A 405
+
Sbjct: 189 S 189
>gi|29568105 transmembrane protein with EGF-like and two
follistatin-like domains 1 [Homo sapiens]
Length = 380
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/107 (28%), Positives = 44/107 (41%), Gaps = 22/107 (20%)
Query: 501 NVNCGCKI----HEYEPVCGSDGITYFNPCL---AGCVNSGNLSTGIRNYTECTCVQSRQ 553
NV C C I + + PVC SDG +Y NPC A C+ + IR+ CT
Sbjct: 185 NVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQID--IRHLGHCTDTDDTS 242
Query: 554 VI---------TPPTVGQRSQLRVVIVKTYL----NENGYAVSGKCK 587
++ P Q V + ++ N NGY + GKC+
Sbjct: 243 LLGKKDDGLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCIHGKCE 289
Score = 30.4 bits (67), Expect = 6.7
Identities = 13/28 (46%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 502 VNCGCKIH---EYEPVCGSDGITYFNPC 526
+ C C+ Y PVCGS+G TY N C
Sbjct: 95 LKCACQFQCHTNYIPVCGSNGDTYQNEC 122
>gi|194239645 spinster homolog 3 [Homo sapiens]
Length = 512
Score = 43.9 bits (102), Expect = 6e-04
Identities = 40/172 (23%), Positives = 68/172 (39%), Gaps = 44/172 (25%)
Query: 149 LSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFG 208
++ V+ I+ + + + +GLL + F L+ Y G R R ++ G +L+ G
Sbjct: 65 IAGVLLDIQEVFQISDNHAGLLQTVFVSCLLLSAPVFGYLGDRHSRKATMSFG-ILLWSG 123
Query: 209 AALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFI 268
A L + FISP Y W LF
Sbjct: 124 AGLSS--SFISPRYS-------------------------------------W----LFF 140
Query: 269 CAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLG 320
++ ++G GS T+ PT L D ++ + LA+ Y+ +G +GY+LG
Sbjct: 141 LSRGIVGTGSASYSTIAPTVLGDLFVRDQRTRVLAVFYIFIPVGSGLGYVLG 192
>gi|185136021 spinster homolog 2 [Homo sapiens]
Length = 549
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/172 (22%), Positives = 64/172 (37%), Gaps = 44/172 (25%)
Query: 149 LSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFG 208
++ V+ I++ + +K +GLL S F +V Y G R R + L+ G I F
Sbjct: 122 VAGVLLDIQQHFGVKDRGAGLLQSVFICSFMVAAPIFGYLGDRFNRKVILSCG---IFFW 178
Query: 209 AALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFI 268
+A+ FI Y W L +
Sbjct: 179 SAVTFSSSFIPQQY-------------------------------------FW----LLV 197
Query: 269 CAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLG 320
++ L+G+G T+ PT + D K +L L++ Y LG +GY+ G
Sbjct: 198 LSRGLVGIGEASYSTIAPTIIGDLFTKNTRTLMLSVFYFAIPLGSGLGYITG 249
>gi|215490102 spinster homolog 1 isoform 3 [Homo sapiens]
Length = 476
Score = 38.9 bits (89), Expect = 0.019
Identities = 42/194 (21%), Positives = 73/194 (37%), Gaps = 45/194 (23%)
Query: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
S + +C++ + M ++ V+ IE+ +++ S SGL+ + F +V+
Sbjct: 58 SALIVAVLCYINLLN-YMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFG 116
Query: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATL 246
Y G R R +L GG IAF + + FI
Sbjct: 117 YLGDRYNRK-YLMCGG--IAFWSLVTLGSSFIP--------------------------- 146
Query: 247 EPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMY 306
G + W L + + L+G+G T+ PT + D + S L+I Y
Sbjct: 147 ----------GEHFW----LLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFY 192
Query: 307 VMGALGPAVGYLLG 320
+G +GY+ G
Sbjct: 193 FAIPVGSGLGYIAG 206
>gi|215490096 spinster homolog 1 isoform 1 [Homo sapiens]
Length = 528
Score = 38.9 bits (89), Expect = 0.019
Identities = 42/194 (21%), Positives = 73/194 (37%), Gaps = 45/194 (23%)
Query: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
S + +C++ + M ++ V+ IE+ +++ S SGL+ + F +V+
Sbjct: 58 SALIVAVLCYINLLN-YMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFG 116
Query: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATL 246
Y G R R +L GG IAF + + FI
Sbjct: 117 YLGDRYNRK-YLMCGG--IAFWSLVTLGSSFIP--------------------------- 146
Query: 247 EPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMY 306
G + W L + + L+G+G T+ PT + D + S L+I Y
Sbjct: 147 ----------GEHFW----LLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFY 192
Query: 307 VMGALGPAVGYLLG 320
+G +GY+ G
Sbjct: 193 FAIPVGSGLGYIAG 206
>gi|14042968 spinster homolog 1 isoform 1 [Homo sapiens]
Length = 528
Score = 38.9 bits (89), Expect = 0.019
Identities = 42/194 (21%), Positives = 73/194 (37%), Gaps = 45/194 (23%)
Query: 127 SRCFLVCMCFLTFIQALMVSGYLSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVS 186
S + +C++ + M ++ V+ IE+ +++ S SGL+ + F +V+
Sbjct: 58 SALIVAVLCYINLLN-YMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFG 116
Query: 187 YFGGRGRRPLWLAVGGLLIAFGAALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATL 246
Y G R R +L GG IAF + + FI
Sbjct: 117 YLGDRYNRK-YLMCGG--IAFWSLVTLGSSFIP--------------------------- 146
Query: 247 EPPACPKDSGGNNHWVYVALFICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMY 306
G + W L + + L+G+G T+ PT + D + S L+I Y
Sbjct: 147 ----------GEHFW----LLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFY 192
Query: 307 VMGALGPAVGYLLG 320
+G +GY+ G
Sbjct: 193 FAIPVGSGLGYIAG 206
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 37.7 bits (86), Expect = 0.042
Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 5/58 (8%)
Query: 504 CGCKIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTEC---TCVQSRQVITPP 558
C CK PVCGSDG TY + C + S G + T+ TC Q ++TPP
Sbjct: 111 CVCKSRY--PVCGSDGTTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPP 166
>gi|215490100 spinster homolog 1 isoform 2 [Homo sapiens]
Length = 455
Score = 37.7 bits (86), Expect = 0.042
Identities = 39/172 (22%), Positives = 65/172 (37%), Gaps = 44/172 (25%)
Query: 149 LSSVITTIERRYSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFG 208
++ V+ IE+ +++ S SGL+ + F +V+ Y G R R +L GG IAF
Sbjct: 6 VAGVLPDIEQFFNIGDSSSGLIQTVFISSYMVLAPVFGYLGDRYNRK-YLMCGG--IAFW 62
Query: 209 AALFALPHFISPPYQIQELNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVALFI 268
+ + FI G + W L +
Sbjct: 63 SLVTLGSSFIP-------------------------------------GEHFW----LLL 81
Query: 269 CAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLG 320
+ L+G+G T+ PT + D + S L+I Y +G +GY+ G
Sbjct: 82 LTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAG 133
>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
sapiens]
Length = 97
Score = 35.8 bits (81), Expect = 0.16
Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 511 YEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYTECTC 548
Y+P+CG++ ITY NPC+ CV S IR Y + C
Sbjct: 61 YQPICGTNFITYDNPCIL-CVESLKSHGRIRFYHDGKC 97
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,844,719
Number of Sequences: 37866
Number of extensions: 1578398
Number of successful extensions: 5803
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 53
Number of HSP's that attempted gapping in prelim test: 5579
Number of HSP's gapped (non-prelim): 182
length of query: 793
length of database: 18,247,518
effective HSP length: 110
effective length of query: 683
effective length of database: 14,082,258
effective search space: 9618182214
effective search space used: 9618182214
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.