Guide to the Human Genome
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Search of human proteins with 225543288

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo
sapiens]
         (266 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo s...   538   e-153
gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo s...   494   e-140
gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo sap...   485   e-137
gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo sap...   478   e-135
gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sa...   111   7e-25
gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]             108   4e-24
gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]             108   4e-24
gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo ...   100   2e-21
gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo...    91   1e-18
gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens]      87   2e-17
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]           58   1e-08
gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens]     56   4e-08
gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]     56   4e-08
gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens]              48   8e-06
gi|222144229 APG7 autophagy 7-like isoform c [Homo sapiens]            37   0.018
gi|222144227 APG7 autophagy 7-like isoform b [Homo sapiens]            37   0.018
gi|5453668 APG7 autophagy 7-like isoform a [Homo sapiens]              37   0.018
gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens]     35   0.089
gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens]     35   0.089
gi|193788653 hypothetical protein LOC100131897 [Homo sapiens]          32   0.75 
gi|104526627 triadin [Homo sapiens]                                    28   6.4  

>gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo
           sapiens]
          Length = 266

 Score =  538 bits (1385), Expect = e-153
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60
           MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
Sbjct: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60

Query: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120
           KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
Sbjct: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120

Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180
           SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180

Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240
           VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240

Query: 241 FLLQGTASPRWPQCVRWLEGFWHRKL 266
           FLLQGTASPRWPQCVRWLEGFWHRKL
Sbjct: 241 FLLQGTASPRWPQCVRWLEGFWHRKL 266


>gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo
           sapiens]
          Length = 299

 Score =  494 bits (1272), Expect = e-140
 Identities = 253/266 (95%), Positives = 255/266 (95%), Gaps = 4/266 (1%)

Query: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60
           MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
Sbjct: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60

Query: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120
           KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
Sbjct: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120

Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180
           SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180

Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240
           VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240

Query: 241 FLLQG--TASPRWPQ--CVRWLEGFW 262
           FLLQG  +A P   Q   +RW EG W
Sbjct: 241 FLLQGPVSAGPSSQQLLLLRWHEGEW 266


>gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo
           sapiens]
          Length = 346

 Score =  485 bits (1248), Expect = e-137
 Identities = 244/244 (100%), Positives = 244/244 (100%)

Query: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60
           MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
Sbjct: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60

Query: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120
           KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
Sbjct: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120

Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180
           SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180

Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240
           VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
Sbjct: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240

Query: 241 FLLQ 244
           FLLQ
Sbjct: 241 FLLQ 244


>gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo
           sapiens]
          Length = 346

 Score =  478 bits (1229), Expect = e-135
 Identities = 240/244 (98%), Positives = 241/244 (98%)

Query: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60
           MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
Sbjct: 1   MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV 60

Query: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120
           KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
Sbjct: 61  KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE 120

Query: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK 180
           SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGD FGYHGYTFANLGEHEFVEE+T 
Sbjct: 121 SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDAFGYHGYTFANLGEHEFVEEETD 180

Query: 181 VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240
           VAKVS GVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
Sbjct: 181 VAKVSHGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY 240

Query: 241 FLLQ 244
           FLLQ
Sbjct: 241 FLLQ 244


>gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo
           sapiens]
          Length = 1012

 Score =  111 bits (277), Expect = 7e-25
 Identities = 65/171 (38%), Positives = 92/171 (53%), Gaps = 3/171 (1%)

Query: 19  YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGA 78
           Y RQ+ + G  A +R++ +RVL+ GL+GLGAE+AKNL+L GV  LT+ D       D  A
Sbjct: 15  YSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAA 74

Query: 79  QFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
           QFL+    + R+RAEAS E    LN  V V V T DI    E     F  V LT    + 
Sbjct: 75  QFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDI---TEDLLLDFQVVVLTAAKLEE 131

Query: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVE 189
            +KV  +CHK+ + F   D  G  G  F + GE   V++ T+   ++  ++
Sbjct: 132 QLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQ 182



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 41/123 (33%), Positives = 65/123 (52%), Gaps = 10/123 (8%)

Query: 17  AQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVK-----GLTMLDHEQV 71
           ++YD QI ++G   Q++LR    LLVG   +G E+ K   L G+      GLT++D + +
Sbjct: 413 SRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHI 472

Query: 72  TPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-----SFFTQF 126
              +   QFL R+  VGR +AE +   A+ LNP + V   T  ++   E     +FF++ 
Sbjct: 473 ERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRV 532

Query: 127 DAV 129
           D V
Sbjct: 533 DGV 535


>gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]
          Length = 1058

 Score =  108 bits (271), Expect = 4e-24
 Identities = 69/188 (36%), Positives = 94/188 (50%), Gaps = 7/188 (3%)

Query: 9   GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
           G  ++ +   Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D 
Sbjct: 45  GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104

Query: 69  EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128
                 D  +QF +R   +G+NRAE S  R   LN  V V   T  +    E F + F  
Sbjct: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQV 161

Query: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE----EKTKVAKV 184
           V LT    +  ++V + CH   IK    D  G  G  F + GE   +     E+   A V
Sbjct: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221

Query: 185 SQGVEDGP 192
           S   +D P
Sbjct: 222 SMVTKDNP 229



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%)

Query: 18  QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72
           +YD Q+ ++G + Q++L   +  LVG   +G E+ KN  + G+       + + D + + 
Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509

Query: 73  PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125
             +   QFL R   V + +++ +    + +NP + V         DTE I    + FF  
Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567

Query: 126 FDAVCLTCCSRDVIVKVDQIC 146
            D V     + D  + +D+ C
Sbjct: 568 LDGVANALDNVDARMYMDRRC 588


>gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]
          Length = 1058

 Score =  108 bits (271), Expect = 4e-24
 Identities = 69/188 (36%), Positives = 94/188 (50%), Gaps = 7/188 (3%)

Query: 9   GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
           G  ++ +   Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D 
Sbjct: 45  GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104

Query: 69  EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128
                 D  +QF +R   +G+NRAE S  R   LN  V V   T  +    E F + F  
Sbjct: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQV 161

Query: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE----EKTKVAKV 184
           V LT    +  ++V + CH   IK    D  G  G  F + GE   +     E+   A V
Sbjct: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221

Query: 185 SQGVEDGP 192
           S   +D P
Sbjct: 222 SMVTKDNP 229



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%)

Query: 18  QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72
           +YD Q+ ++G + Q++L   +  LVG   +G E+ KN  + G+       + + D + + 
Sbjct: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509

Query: 73  PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125
             +   QFL R   V + +++ +    + +NP + V         DTE I    + FF  
Sbjct: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567

Query: 126 FDAVCLTCCSRDVIVKVDQIC 146
            D V     + D  + +D+ C
Sbjct: 568 LDGVANALDNVDARMYMDRRC 588


>gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo
           sapiens]
          Length = 534

 Score =  100 bits (248), Expect = 2e-21
 Identities = 55/162 (33%), Positives = 84/162 (51%), Gaps = 3/162 (1%)

Query: 18  QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPG 77
           +YDRQ+RLWG   Q+ L ++ V L+     G EI KNL+L G+   T++D  QV+ ED G
Sbjct: 12  KYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAG 71

Query: 78  AQFLIRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCC 134
             F ++  S+G+NRAEA++E  Q LN  V    V+   E++     SFF +F  V  T  
Sbjct: 72  NNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQL 131

Query: 135 SRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
                +++  +   + I       +G  GY    + EH  +E
Sbjct: 132 PESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 173


>gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo
           sapiens]
          Length = 528

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 51/158 (32%), Positives = 79/158 (50%), Gaps = 3/158 (1%)

Query: 22  QIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFL 81
           + RLWG   Q+ L ++ V L+     G EI KNL+L G+   T++D  QV+ ED G  F 
Sbjct: 10  EARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFF 69

Query: 82  IRTGSVGRNRAEASLERAQNLNPMVD---VKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
           ++  S+G+NRAEA++E  Q LN  V    V+   E++     SFF +F  V  T      
Sbjct: 70  LQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129

Query: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE 176
            +++  +   + I       +G  GY    + EH  +E
Sbjct: 130 SLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIE 167


>gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens]
          Length = 1052

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 60/172 (34%), Positives = 85/172 (49%), Gaps = 5/172 (2%)

Query: 13  EEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVT 72
           E + A Y RQ  + G  A +++  S V L G+ GLG EIAKNL+LAG+K +T+ D E+  
Sbjct: 38  EIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQ 97

Query: 73  PEDPGAQFLIRTGSV--GRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-SFFTQFDAV 129
             D G  F +    V   RNRAEA L+    LNP V V   +    +  + SF  ++  V
Sbjct: 98  AWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCV 157

Query: 130 CLTCCSRDVIVKVDQICHKN--SIKFFTGDVFGYHGYTFANLGEHEFVEEKT 179
            LT     +  K++  C      IKF + DV G     F + G+   V + T
Sbjct: 158 VLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTT 209



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 31/145 (21%), Positives = 59/145 (40%), Gaps = 11/145 (7%)

Query: 32  KRLRASRVLLVGLKGLGAEIAKNLILAGV-----KG-LTMLDHEQVTPEDPGAQFLIRTG 85
           ++L+   + LVG   +G E+ KN  L GV     KG +T+ D + +   +   QFL R  
Sbjct: 456 QKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNLNRQFLFRPH 515

Query: 86  SVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPES-----FFTQFDAVCLTCCSRDVIV 140
            + + ++  + +    +N  + +      +    E+     F+T+ D +     + +   
Sbjct: 516 HIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQDVIITALDNVEARR 575

Query: 141 KVDQICHKNSIKFFTGDVFGYHGYT 165
            VD  C  N          G  G+T
Sbjct: 576 YVDSRCLANLRPLLDSGTMGTKGHT 600


>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
          Length = 640

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 4/138 (2%)

Query: 29  EAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVG 88
           E  + +   RVL+VG  G+G E+ KNL+L G   + ++D + +   +   QFL +   VG
Sbjct: 10  ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVG 69

Query: 89  RNRAEASLERAQNLNPMVDVKVDTEDIEKKPE---SFFTQFDAVCLTCCSRDVIVKVDQI 145
           R++A+ + E      P  ++ V   D    P+    FF QF  V     +R     V+++
Sbjct: 70  RSKAQVAKESVLQFYPKANI-VAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRM 128

Query: 146 CHKNSIKFFTGDVFGYHG 163
           C    +        GY G
Sbjct: 129 CLAADVPLIESGTAGYLG 146


>gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens]
          Length = 449

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 3/107 (2%)

Query: 34  LRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAE 93
           L   +VL++G  GLG E+ KNL L+G + + ++D + +   +   QFL R   +GR +AE
Sbjct: 53  LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 112

Query: 94  ASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIV 140
            + E   +  P  +V      I+   ++F+ QF  +    C  D I+
Sbjct: 113 VAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII---VCGLDSII 156


>gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]
          Length = 463

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 3/107 (2%)

Query: 34  LRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAE 93
           L   +VL++G  GLG E+ KNL L+G + + ++D + +   +   QFL R   +GR +AE
Sbjct: 67  LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 126

Query: 94  ASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIV 140
            + E   +  P  +V      I+   ++F+ QF  +    C  D I+
Sbjct: 127 VAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHII---VCGLDSII 170


>gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens]
          Length = 460

 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 2/99 (2%)

Query: 11  ISEEEAAQYDRQIRL--WGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
           +S +E  +Y RQ+ L   G+  Q RL  + VL+VG  GLG  +A+ L  AGV  L ++D+
Sbjct: 55  LSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDY 114

Query: 69  EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVD 107
           + V   +   Q L      G+ +A ++    + LN  V+
Sbjct: 115 DVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVE 153


>gi|222144229 APG7 autophagy 7-like isoform c [Homo sapiens]
          Length = 623

 Score = 37.0 bits (84), Expect = 0.018
 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%)

Query: 38  RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV---GRNRAEA 94
           + LL+G   LG  +A+ L+  GV+ +T +D+ +++  +P  Q L         G+ +A A
Sbjct: 318 KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALA 377

Query: 95  SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154
           + +R Q + P V+ +     I          F +V L    RDV  +++Q+   + + F 
Sbjct: 378 AADRLQKIFPGVNARGFNMSIPMPGHP--VNFSSVTLEQARRDV-EQLEQLIESHDVVFL 434

Query: 155 TGD 157
             D
Sbjct: 435 LMD 437


>gi|222144227 APG7 autophagy 7-like isoform b [Homo sapiens]
          Length = 676

 Score = 37.0 bits (84), Expect = 0.018
 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%)

Query: 38  RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV---GRNRAEA 94
           + LL+G   LG  +A+ L+  GV+ +T +D+ +++  +P  Q L         G+ +A A
Sbjct: 357 KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALA 416

Query: 95  SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154
           + +R Q + P V+ +     I          F +V L    RDV  +++Q+   + + F 
Sbjct: 417 AADRLQKIFPGVNARGFNMSIPMPGHP--VNFSSVTLEQARRDV-EQLEQLIESHDVVFL 473

Query: 155 TGD 157
             D
Sbjct: 474 LMD 476


>gi|5453668 APG7 autophagy 7-like isoform a [Homo sapiens]
          Length = 703

 Score = 37.0 bits (84), Expect = 0.018
 Identities = 31/123 (25%), Positives = 58/123 (47%), Gaps = 6/123 (4%)

Query: 38  RVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSV---GRNRAEA 94
           + LL+G   LG  +A+ L+  GV+ +T +D+ +++  +P  Q L         G+ +A A
Sbjct: 357 KCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALA 416

Query: 95  SLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFF 154
           + +R Q + P V+ +     I          F +V L    RDV  +++Q+   + + F 
Sbjct: 417 AADRLQKIFPGVNARGFNMSIPMPGHP--VNFSSVTLEQARRDV-EQLEQLIESHDVVFL 473

Query: 155 TGD 157
             D
Sbjct: 474 LMD 476


>gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens]
          Length = 348

 Score = 34.7 bits (78), Expect = 0.089
 Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 32  KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91
           +++R   V +VG+ G+G+  A+ L   G+  L + D+++V   +    F  +    G ++
Sbjct: 13  EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 71

Query: 92  AEASLERAQNLNPMVDVKVDTEDI 115
            +A+    +N+NP V  +V   +I
Sbjct: 72  VQAAEHTLRNINPDVLFEVHNYNI 95


>gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens]
          Length = 404

 Score = 34.7 bits (78), Expect = 0.089
 Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 32  KRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGAQFLIRTGSVGRNR 91
           +++R   V +VG+ G+G+  A+ L   G+  L + D+++V   +    F  +    G ++
Sbjct: 69  EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLF-FQPHQAGLSK 127

Query: 92  AEASLERAQNLNPMVDVKVDTEDI 115
            +A+    +N+NP V  +V   +I
Sbjct: 128 VQAAEHTLRNINPDVLFEVHNYNI 151


>gi|193788653 hypothetical protein LOC100131897 [Homo sapiens]
          Length = 535

 Score = 31.6 bits (70), Expect = 0.75
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 10/86 (11%)

Query: 168 NLGEHEFVEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEV-DWSS 226
           NL E + V       +++Q +EDGP  +R K+  +    V K     PV   LE   W S
Sbjct: 137 NLSEQDIVSSDLAYLRLAQHLEDGP--RRVKVSHAFLPRVPKVQSNGPVSICLEAGTWRS 194

Query: 227 -EKAKAALKRTTSDYFLLQGTASPRW 251
            EKA AA++     Y       SP W
Sbjct: 195 LEKATAAIQVPDDIYH------SPSW 214


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 28.5 bits (62), Expect = 6.4
 Identities = 14/36 (38%), Positives = 23/36 (63%)

Query: 175 VEEKTKVAKVSQGVEDGPDTKRAKLDSSETTMVKKK 210
           V +  K A+VS+ VED P +K+AK  + + +  K+K
Sbjct: 648 VTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQK 683


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,733,734
Number of Sequences: 37866
Number of extensions: 390626
Number of successful extensions: 1205
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1169
Number of HSP's gapped (non-prelim): 28
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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