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Search of human proteins with 115527076
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115527076 src kinase associated phosphoprotein 1 isoform 2
[Homo sapiens]
(358 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H... 743 0.0
gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [H... 738 0.0
gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens] 293 2e-79
gi|11321634 CD2-associated protein [Homo sapiens] 58 1e-08
gi|188497618 connector enhancer of kinase suppressor of Ras 1 [H... 55 1e-07
gi|194733753 phosphoinositide-binding protein PIP3-E isoform 1 [... 54 2e-07
gi|194733747 phosphoinositide-binding protein PIP3-E isoform 1 [... 54 2e-07
gi|40354212 phosphoinositide-binding protein PIP3-E isoform 2 [H... 54 2e-07
gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Ho... 54 2e-07
gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo... 53 5e-07
gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Ho... 52 1e-06
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 51 2e-06
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 51 2e-06
gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo... 50 2e-06
gi|154354979 myosin X [Homo sapiens] 50 4e-06
gi|93102364 SWAP-70 protein [Homo sapiens] 49 7e-06
gi|109689723 abl interactor 2 [Homo sapiens] 48 2e-05
gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens] 47 2e-05
gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens] 47 2e-05
gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens] 47 2e-05
gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens] 47 2e-05
gi|189491778 nephrocystin 1 isoform 4 [Homo sapiens] 47 2e-05
gi|189491776 nephrocystin 1 isoform 3 [Homo sapiens] 47 2e-05
gi|189491774 nephrocystin 1 isoform 2 [Homo sapiens] 47 2e-05
gi|46397398 nephrocystin 1 isoform 1 [Homo sapiens] 47 2e-05
gi|224586880 Ras protein-specific guanine nucleotide-releasing f... 47 3e-05
gi|24797099 Ras protein-specific guanine nucleotide-releasing fa... 47 3e-05
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 47 3e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 47 3e-05
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens] 46 6e-05
>gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo
sapiens]
Length = 358
Score = 743 bits (1918), Expect = 0.0
Identities = 358/358 (100%), Positives = 358/358 (100%)
Query: 1 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG 60
MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG
Sbjct: 1 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG 60
Query: 61 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD 120
GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD
Sbjct: 61 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD 120
Query: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180
HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL
Sbjct: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180
Query: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240
TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS
Sbjct: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240
Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGDYASYYQG 300
PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGDYASYYQG
Sbjct: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGDYASYYQG 300
Query: 301 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 358
LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER
Sbjct: 301 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 358
>gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo
sapiens]
Length = 359
Score = 738 bits (1906), Expect = 0.0
Identities = 358/359 (99%), Positives = 358/359 (99%), Gaps = 1/359 (0%)
Query: 1 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG 60
MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG
Sbjct: 1 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG 60
Query: 61 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD 120
GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD
Sbjct: 61 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD 120
Query: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180
HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL
Sbjct: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180
Query: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240
TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS
Sbjct: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240
Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKG-DYASYYQ 299
PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKG DYASYYQ
Sbjct: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQ 300
Query: 300 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 358
GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER
Sbjct: 301 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 359
>gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens]
Length = 359
Score = 293 bits (750), Expect = 2e-79
Identities = 158/369 (42%), Positives = 224/369 (60%), Gaps = 41/369 (11%)
Query: 6 LPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQGGDIGQ 65
LPEEIR LL D E F+A+ L+ ENLS A++ R+ +++ + +K+ Y +FQ +G
Sbjct: 13 LPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYLQEFQDKGDAEDG 72
Query: 66 DSSDDNHSGTLG-LSLTSDAPFLSDYQDEGMEDIVK----GAQELDNVIKQGYLEKKSKD 120
+ DD +G +SL S+ D DE D + AQ+L V+K GYLEK+ KD
Sbjct: 73 EEYDDPFAGPPDTISLASER---YDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKD 129
Query: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180
HSF G EWQKRWC +S+ +FYYY ++K KQ KG F I GY VRM LR+D KK+ CFE+
Sbjct: 130 HSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKDGKKDCCFEI 189
Query: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240
++ D+R Y+FTA SP +A +WV Q+ F+L+D+ S IP E+ +E+ E YDD+D
Sbjct: 190 SAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIP----EDYDERGELYDDVD---- 241
Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHD-----LEEDESGTR------ 289
P + + +P +++IYE LP+EE D +EE ++
Sbjct: 242 -------HPLPISNPLTSSQPI----DDEIYEELPEEEEDSAPVKVEEQRKMSQDSVHHT 290
Query: 290 ---RKGDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPK 346
+ DYA++YQGLWDC G DELSF+RGD+I ILSKEYN YGWWVGE+ +G+VPK
Sbjct: 291 SGDKSTDYANFYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPK 350
Query: 347 EYLTTAFEV 355
Y+ +++
Sbjct: 351 AYIMEMYDI 359
>gi|11321634 CD2-associated protein [Homo sapiens]
Length = 639
Score = 57.8 bits (138), Expect = 1e-08
Identities = 32/98 (32%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Query: 262 TEEKEEED--IYEVLPDEEHDLEEDESGTRRKGDYASYYQGLWDCHGDQPDELSFQRGDL 319
TEEK+ E I + L + +E ++ T K Y + L+ G DEL+F+ G++
Sbjct: 236 TEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEI 295
Query: 320 IRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEE 357
I ++SKE GWW GELN G+ P + E+++
Sbjct: 296 IHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDK 333
Score = 33.5 bits (75), Expect = 0.30
Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 310 DELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 349
DEL + GD+I I E GWW G LN+ +G+ P ++
Sbjct: 125 DELELKVGDIIDI--NEEVEEGWWSGTLNNKLGLFPSNFV 162
Score = 30.0 bits (66), Expect = 3.3
Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 302 WDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 349
+D DEL+ + G++IR + K+ GW GELN G+ P ++
Sbjct: 8 YDYDAVHDDELTIRVGEIIRNV-KKLQEEGWLEGELNGRRGMFPDNFV 54
>gi|188497618 connector enhancer of kinase suppressor of Ras 1 [Homo
sapiens]
Length = 713
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/228 (22%), Positives = 85/228 (37%), Gaps = 12/228 (5%)
Query: 73 SGTLGLSLTSDAPFLSDYQDEGMEDIVK----GAQELDNVIKQGYLEKKSKDHSFFGSEW 128
+GT GL + D + + +G+ + +EL G+L + F G W
Sbjct: 358 AGTPGLPESPDKSPVGRKKSKGLATRLSRRRVSCRELGRPDCDGWLLLRKAPGGFMGPRW 417
Query: 129 QKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSY 188
++RW V+ Y+Y + ++ +G + Y + D KK+ F+LT + +
Sbjct: 418 RRRWFVLKGHTLYWYRQPQDEKAEGLINVSNYSLESG----HDQKKKYVFQLTHDVYKPF 473
Query: 189 EFTATSPAEARDWVDQISFLLKDLSS---LTIPYEEDEEEEEKEETYDDIDGFDSPSCGS 245
F A + + WV + + S P EED E + E DD G S S
Sbjct: 474 IFAADTLTDLSMWVRHLITCISKYQSPGRAPPPREEDCYSETEAEDPDDEAGSHSASPSP 533
Query: 246 QCRPTILPGSVG-IKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKG 292
+ L G PT+ + E LE G R+ G
Sbjct: 534 AQAGSPLHGDTSPAATPTQRSPRTSFGSLTDSSEEALEGMVRGLRQGG 581
>gi|194733753 phosphoinositide-binding protein PIP3-E isoform 1
[Homo sapiens]
Length = 438
Score = 54.3 bits (129), Expect = 2e-07
Identities = 30/127 (23%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 103 QELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGV 162
++L + QG+L KK + SF ++W+K W ++ Y+Y+N+ +++ G + + V
Sbjct: 38 KDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTV 97
Query: 163 RMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIP---Y 219
A + KK+ F+++ +++ F A + E W++++ + S T Y
Sbjct: 98 ERA----SECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECY 153
Query: 220 EEDEEEE 226
E E+E+
Sbjct: 154 SESEQED 160
>gi|194733747 phosphoinositide-binding protein PIP3-E isoform 1
[Homo sapiens]
Length = 438
Score = 54.3 bits (129), Expect = 2e-07
Identities = 30/127 (23%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 103 QELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGV 162
++L + QG+L KK + SF ++W+K W ++ Y+Y+N+ +++ G + + V
Sbjct: 38 KDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTV 97
Query: 163 RMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIP---Y 219
A + KK+ F+++ +++ F A + E W++++ + S T Y
Sbjct: 98 ERA----SECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECY 153
Query: 220 EEDEEEE 226
E E+E+
Sbjct: 154 SESEQED 160
>gi|40354212 phosphoinositide-binding protein PIP3-E isoform 2 [Homo
sapiens]
Length = 437
Score = 54.3 bits (129), Expect = 2e-07
Identities = 30/127 (23%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 103 QELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGV 162
++L + QG+L KK + SF ++W+K W ++ Y+Y+N+ +++ G + + V
Sbjct: 37 KDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTV 96
Query: 163 RMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIP---Y 219
A + KK+ F+++ +++ F A + E W++++ + S T Y
Sbjct: 97 ERA----SECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECY 152
Query: 220 EEDEEEE 226
E E+E+
Sbjct: 153 SESEQED 159
>gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Homo
sapiens]
Length = 1034
Score = 54.3 bits (129), Expect = 2e-07
Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 13/141 (9%)
Query: 111 QGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRR 170
+G+L KK S+F +W+K W V+ Y+Y NE+ ++ +G + + + A R
Sbjct: 574 EGWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKAEGFISLPEFKIDRASECR- 632
Query: 171 DSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEE 230
K+ F+ +S+ F A + W+++I+ LT Y E E +++++
Sbjct: 633 ---KKYAFKACHPKIKSFYFAAEHLDDMNRWLNRINM-------LTAGYAERERIKQEQD 682
Query: 231 TYDDID--GFDSPSCGSQCRP 249
+ + D D+PS Q P
Sbjct: 683 YWSESDKEEADTPSTPKQDSP 703
>gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo
sapiens]
Length = 323
Score = 52.8 bits (125), Expect = 5e-07
Identities = 34/150 (22%), Positives = 63/150 (42%), Gaps = 13/150 (8%)
Query: 207 FLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKE 266
F +D+ + I + + + E+ Y+ +D F R + ++ E+
Sbjct: 179 FYCQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQR-------INARKAAREQR 231
Query: 267 EEDIYEVLPDEEHDLEEDE------SGTRRKGDYASYYQGLWDCHGDQPDELSFQRGDLI 320
+ E+ P ++ SG++ + L+ G QP +L+FQ GD I
Sbjct: 232 KSSAKELPPKPLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRI 291
Query: 321 RILSKEYNMYGWWVGELNSLVGIVPKEYLT 350
++SK + + WW G+L GI P Y+T
Sbjct: 292 TVISKTDSHFDWWEGKLRGQTGIFPANYVT 321
>gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Homo
sapiens]
Length = 1118
Score = 51.6 bits (122), Expect = 1e-06
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 21/106 (19%)
Query: 253 PGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGDYAS-----YYQGLWDCHGD 307
PG G EE+EEE EE+ + G+ Y+ +++
Sbjct: 20 PGEDGAGAGAEEEEEE-------------EEEAAAAVGPGELGCDAPLPYWTAVFEYEAA 66
Query: 308 QPDELSFQRGDLIRILSKEYNMYG---WWVGELNSLVGIVPKEYLT 350
DEL+ + GD++ +LSK+ + G WW G+LN VGI P Y+T
Sbjct: 67 GEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVT 112
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 16/109 (14%)
Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGDYASYYQG 300
PS G+ P++ PG K Y+ PD + E Y+
Sbjct: 145 PSLGNPDMPSVSPGP-----QRPPKLSSLAYDSPPDYLQTVSHPE-----------VYRV 188
Query: 301 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 349
L+D + PDEL+ +RGD++++LSK GWW GE G+ P ++
Sbjct: 189 LFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 237
Score = 35.0 bits (79), Expect = 0.10
Identities = 13/43 (30%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 307 DQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 349
+Q DEL Q G+++ ++ + + GWW+G+ N +G P ++
Sbjct: 97 EQADELKLQAGEIVEMIKEIED--GWWLGKKNGQLGAFPSNFV 137
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 16/109 (14%)
Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGDYASYYQG 300
PS G+ P++ PG K Y+ PD + E Y+
Sbjct: 34 PSLGNPDMPSVSPGP-----QRPPKLSSLAYDSPPDYLQTVSHPE-----------VYRV 77
Query: 301 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 349
L+D + PDEL+ +RGD++++LSK GWW GE G+ P ++
Sbjct: 78 LFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 126
>gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo
sapiens]
Length = 342
Score = 50.4 bits (119), Expect = 2e-06
Identities = 21/50 (42%), Positives = 30/50 (60%)
Query: 301 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLT 350
L+ G QP +L+FQ GD I ++SK + + WW G+L GI P Y+T
Sbjct: 291 LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 49.7 bits (117), Expect = 4e-06
Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%)
Query: 109 IKQGYLEKKSKDHSFFGSE-WQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPH 167
+KQG+L KK S W+KRW V+ + Y+ N+ ++ KGT VR A
Sbjct: 1214 LKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGT-----VEVRTAKE 1268
Query: 168 LRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQIS 206
+ ++ KE+ ++ D R++ A SP +A W +S
Sbjct: 1269 IIDNTTKENGIDIIMAD-RTFHLIAESPEDASQWFSVLS 1306
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 48.9 bits (115), Expect = 7e-06
Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 9/124 (7%)
Query: 107 NVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLI-KGYGVRMA 165
+V+KQGY+ KK W +RW V+ + YY +E K KG L+ + V
Sbjct: 210 DVLKQGYMMKKGHRRK----NWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESL 265
Query: 166 PHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEE 225
P +D KK C L +++E +A+ + ++W+ I + L + P ++ +
Sbjct: 266 PD--KDGKK--CLFLVKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKEARQ 321
Query: 226 EEKE 229
KE
Sbjct: 322 RRKE 325
>gi|109689723 abl interactor 2 [Homo sapiens]
Length = 475
Score = 47.8 bits (112), Expect = 2e-05
Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Query: 261 PTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGDYASYYQGLWDCHGDQPDELSFQRGDLI 320
P E+ EEE+ V + + EED R Y ++D D+ DELSFQ G +I
Sbjct: 384 PPEDYEEEEAAVVEYSDPY-AEEDPPWAPRS--YLEKVVAIYDYTKDKEDELSFQEGAII 440
Query: 321 RILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEE 357
++ K N GW+ G +N + G+ P Y+ + E
Sbjct: 441 YVIKK--NDDGWYEGVMNGVTGLFPGNYVESIMHYSE 475
>gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens]
Length = 618
Score = 47.4 bits (111), Expect = 2e-05
Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 30/190 (15%)
Query: 101 GAQEL----DNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFL 156
GAQ L V K GYL KK +W R+ ++ + YY+ + S P+G F
Sbjct: 73 GAQNLLTMPGGVAKAGYLHKKGGTQLQL-LKWPLRFVIIHKRCVYYFKSSTSASPQGAFS 131
Query: 157 IKGYGVRMAPHLRRDSKKESCFEL--TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSS 214
+ GY M S F++ S+ R++ F+A+S E + W ++ L +++
Sbjct: 132 LSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSW---MALLRREIGH 188
Query: 215 LTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVL 274
+E+ + + ++ D D F G+ RP + S PT+ +
Sbjct: 189 F---HEKKDLPLDTSDSSSDTDSF----YGAVERPVDISLS---PYPTDNE--------- 229
Query: 275 PDEEHDLEED 284
D EHD E+D
Sbjct: 230 -DYEHDDEDD 238
>gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens]
Length = 589
Score = 47.4 bits (111), Expect = 2e-05
Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 30/190 (15%)
Query: 101 GAQEL----DNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFL 156
GAQ L V K GYL KK +W R+ ++ + YY+ + S P+G F
Sbjct: 44 GAQNLLTMPGGVAKAGYLHKKGGTQLQL-LKWPLRFVIIHKRCVYYFKSSTSASPQGAFS 102
Query: 157 IKGYGVRMAPHLRRDSKKESCFEL--TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSS 214
+ GY M S F++ S+ R++ F+A+S E + W ++ L +++
Sbjct: 103 LSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSW---MALLRREIGH 159
Query: 215 LTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVL 274
+E+ + + ++ D D F G+ RP + S PT+ +
Sbjct: 160 F---HEKKDLPLDTSDSSSDTDSF----YGAVERPVDISLS---PYPTDNE--------- 200
Query: 275 PDEEHDLEED 284
D EHD E+D
Sbjct: 201 -DYEHDDEDD 209
>gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens]
Length = 561
Score = 47.4 bits (111), Expect = 2e-05
Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 30/190 (15%)
Query: 101 GAQEL----DNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFL 156
GAQ L V K GYL KK +W R+ ++ + YY+ + S P+G F
Sbjct: 16 GAQNLLTMPGGVAKAGYLHKKGGTQLQL-LKWPLRFVIIHKRCVYYFKSSTSASPQGAFS 74
Query: 157 IKGYGVRMAPHLRRDSKKESCFEL--TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSS 214
+ GY M S F++ S+ R++ F+A+S E + W ++ L +++
Sbjct: 75 LSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSW---MALLRREIGH 131
Query: 215 LTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVL 274
+E+ + + ++ D D F G+ RP + S PT+ +
Sbjct: 132 F---HEKKDLPLDTSDSSSDTDSF----YGAVERPVDISLS---PYPTDNE--------- 172
Query: 275 PDEEHDLEED 284
D EHD E+D
Sbjct: 173 -DYEHDDEDD 181
>gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens]
Length = 561
Score = 47.4 bits (111), Expect = 2e-05
Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 30/190 (15%)
Query: 101 GAQEL----DNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFL 156
GAQ L V K GYL KK +W R+ ++ + YY+ + S P+G F
Sbjct: 16 GAQNLLTMPGGVAKAGYLHKKGGTQLQL-LKWPLRFVIIHKRCVYYFKSSTSASPQGAFS 74
Query: 157 IKGYGVRMAPHLRRDSKKESCFEL--TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSS 214
+ GY M S F++ S+ R++ F+A+S E + W ++ L +++
Sbjct: 75 LSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSW---MALLRREIGH 131
Query: 215 LTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVL 274
+E+ + + ++ D D F G+ RP + S PT+ +
Sbjct: 132 F---HEKKDLPLDTSDSSSDTDSF----YGAVERPVDISLS---PYPTDNE--------- 172
Query: 275 PDEEHDLEED 284
D EHD E+D
Sbjct: 173 -DYEHDDEDD 181
>gi|189491778 nephrocystin 1 isoform 4 [Homo sapiens]
Length = 614
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 9/104 (8%)
Query: 261 PTEEKEEEDIY--EVLPDEEHDLEED----ESGTRRKGDYASYYQGLWDCHGDQPDELSF 314
PTEE+EE + E EE D EE+ E K Y + D Q +L+F
Sbjct: 52 PTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIAVGDFTAQQVGDLTF 111
Query: 315 QRGDLIRILSKEYNMYGWWVG-ELNSLVGIVPKEYLTTAFEVEE 357
++G+++ ++ K+ + GWW+ + G+VP+ YL E EE
Sbjct: 112 KKGEILLVIEKKPD--GWWIAKDAKGNEGLVPRTYLEPYSEEEE 153
>gi|189491776 nephrocystin 1 isoform 3 [Homo sapiens]
Length = 677
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 9/104 (8%)
Query: 261 PTEEKEEEDIY--EVLPDEEHDLEED----ESGTRRKGDYASYYQGLWDCHGDQPDELSF 314
PTEE+EE + E EE D EE+ E K Y + D Q +L+F
Sbjct: 114 PTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIAVGDFTAQQVGDLTF 173
Query: 315 QRGDLIRILSKEYNMYGWWVG-ELNSLVGIVPKEYLTTAFEVEE 357
++G+++ ++ K+ + GWW+ + G+VP+ YL E EE
Sbjct: 174 KKGEILLVIEKKPD--GWWIAKDAKGNEGLVPRTYLEPYSEEEE 215
>gi|189491774 nephrocystin 1 isoform 2 [Homo sapiens]
Length = 732
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 9/104 (8%)
Query: 261 PTEEKEEEDIY--EVLPDEEHDLEED----ESGTRRKGDYASYYQGLWDCHGDQPDELSF 314
PTEE+EE + E EE D EE+ E K Y + D Q +L+F
Sbjct: 114 PTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIAVGDFTAQQVGDLTF 173
Query: 315 QRGDLIRILSKEYNMYGWWVG-ELNSLVGIVPKEYLTTAFEVEE 357
++G+++ ++ K+ + GWW+ + G+VP+ YL E EE
Sbjct: 174 KKGEILLVIEKKPD--GWWIAKDAKGNEGLVPRTYLEPYSEEEE 215
>gi|46397398 nephrocystin 1 isoform 1 [Homo sapiens]
Length = 733
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 9/104 (8%)
Query: 261 PTEEKEEEDIY--EVLPDEEHDLEED----ESGTRRKGDYASYYQGLWDCHGDQPDELSF 314
PTEE+EE + E EE D EE+ E K Y + D Q +L+F
Sbjct: 114 PTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIAVGDFTAQQVGDLTF 173
Query: 315 QRGDLIRILSKEYNMYGWWVG-ELNSLVGIVPKEYLTTAFEVEE 357
++G+++ ++ K+ + GWW+ + G+VP+ YL E EE
Sbjct: 174 KKGEILLVIEKKPD--GWWIAKDAKGNEGLVPRTYLEPYSEEEE 215
>gi|224586880 Ras protein-specific guanine nucleotide-releasing
factor 1 isoform 3 [Homo sapiens]
Length = 1257
Score = 46.6 bits (109), Expect = 3e-05
Identities = 24/105 (22%), Positives = 53/105 (50%), Gaps = 12/105 (11%)
Query: 110 KQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAP--- 166
++GYL K+S D++ +WQ +W + + L +Y+ ++ S +P G +L++G AP
Sbjct: 25 RKGYLSKRSSDNT----KWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGCVCDRAPSPK 80
Query: 167 ---HLRRDSKKESCF--ELTSQDRRSYEFTATSPAEARDWVDQIS 206
+ +K+ F + +++++ E + +WV I+
Sbjct: 81 PALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEWVAAIA 125
>gi|24797099 Ras protein-specific guanine nucleotide-releasing
factor 1 isoform 1 [Homo sapiens]
Length = 1273
Score = 46.6 bits (109), Expect = 3e-05
Identities = 24/105 (22%), Positives = 53/105 (50%), Gaps = 12/105 (11%)
Query: 110 KQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAP--- 166
++GYL K+S D++ +WQ +W + + L +Y+ ++ S +P G +L++G AP
Sbjct: 25 RKGYLSKRSSDNT----KWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGCVCDRAPSPK 80
Query: 167 ---HLRRDSKKESCF--ELTSQDRRSYEFTATSPAEARDWVDQIS 206
+ +K+ F + +++++ E + +WV I+
Sbjct: 81 PALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEWVAAIA 125
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 46.6 bits (109), Expect = 3e-05
Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
Query: 300 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVE 356
G++D DEL+F +G +I +L+KE WW GE+N VG+ P Y+ +++
Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDP--DWWKGEVNGQVGLFPSNYVKLTTDMD 1216
Score = 34.3 bits (77), Expect = 0.18
Identities = 13/49 (26%), Positives = 26/49 (53%), Gaps = 3/49 (6%)
Query: 301 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 349
++ + +L+FQ+GD+I + K+ + WW G + G+ P Y+
Sbjct: 1010 MYTYESSEQGDLTFQQGDVILVTKKDGD---WWTGTVGDKAGVFPSNYV 1055
Score = 32.7 bits (73), Expect = 0.51
Identities = 15/51 (29%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Query: 299 QGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 349
Q L+ + + L+F + D+I +L ++ WW GE+ G PK Y+
Sbjct: 919 QALYPWRAKKDNHLNFNKNDVITVLEQQDM---WWFGEVQGQKGWFPKSYV 966
Score = 30.8 bits (68), Expect = 2.0
Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 5/57 (8%)
Query: 297 YYQGLWDCHGDQPDELSFQRGDLIRILSK-----EYNMYGWWVGELNSLVGIVPKEY 348
YY+ L+ DE++ Q GD++ + + + GW GEL G P Y
Sbjct: 744 YYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANY 800
Score = 28.9 bits (63), Expect = 7.4
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 7/46 (15%)
Query: 309 PDELSFQRGDLIRILSKEYNMYGWWVGELNS-----LVGIVPKEYL 349
P++L+ G LI I K N GWW GEL + +G P Y+
Sbjct: 1090 PEQLTLAPGQLILIRKK--NPGGWWEGELQARGKKRQIGWFPANYV 1133
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 46.6 bits (109), Expect = 3e-05
Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 2/57 (3%)
Query: 300 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVE 356
G++D DEL+F +G +I +L+KE WW GE+N VG+ P Y+ +++
Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDP--DWWKGEVNGQVGLFPSNYVKLTTDMD 1216
Score = 34.3 bits (77), Expect = 0.18
Identities = 13/49 (26%), Positives = 26/49 (53%), Gaps = 3/49 (6%)
Query: 301 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 349
++ + +L+FQ+GD+I + K+ + WW G + G+ P Y+
Sbjct: 1010 MYTYESSEQGDLTFQQGDVILVTKKDGD---WWTGTVGDKAGVFPSNYV 1055
Score = 32.7 bits (73), Expect = 0.51
Identities = 15/51 (29%), Positives = 26/51 (50%), Gaps = 3/51 (5%)
Query: 299 QGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 349
Q L+ + + L+F + D+I +L ++ WW GE+ G PK Y+
Sbjct: 919 QALYPWRAKKDNHLNFNKNDVITVLEQQDM---WWFGEVQGQKGWFPKSYV 966
Score = 30.8 bits (68), Expect = 2.0
Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 5/57 (8%)
Query: 297 YYQGLWDCHGDQPDELSFQRGDLIRILSK-----EYNMYGWWVGELNSLVGIVPKEY 348
YY+ L+ DE++ Q GD++ + + + GW GEL G P Y
Sbjct: 744 YYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANY 800
Score = 28.9 bits (63), Expect = 7.4
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 7/46 (15%)
Query: 309 PDELSFQRGDLIRILSKEYNMYGWWVGELNS-----LVGIVPKEYL 349
P++L+ G LI I K N GWW GEL + +G P Y+
Sbjct: 1090 PEQLTLAPGQLILIRKK--NPGGWWEGELQARGKKRQIGWFPANYV 1133
>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
Length = 525
Score = 45.8 bits (107), Expect = 6e-05
Identities = 37/183 (20%), Positives = 79/183 (43%), Gaps = 29/183 (15%)
Query: 198 ARDWVDQISFLLKD---------LSSLTIPYEEDEEEEEKEETYDDI------DGFDSPS 242
+RD+ ++ ++K+ L SL + + E+ +++ + +G P
Sbjct: 86 SRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSLISATIKSMKEEGITFPP 145
Query: 243 CGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRR---------KGD 293
GSQ T+ + + KE+EDI + + + ++ + T+
Sbjct: 146 AGSQ---TVSAAAKNGTSSNKNKEDEDIAKAIELSLQEQKQQHTETKSLYPSSEIQLNNK 202
Query: 294 YASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAF 353
A + L+D + +EL+F+ G++I +L + WW GE + +G+ P ++TT
Sbjct: 203 VARKVRALYDFEAVEDNELTFKHGEIIIVLDD--SDANWWKGENHRGIGLFPSNFVTTNL 260
Query: 354 EVE 356
+E
Sbjct: 261 NIE 263
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.135 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,212,063
Number of Sequences: 37866
Number of extensions: 785871
Number of successful extensions: 7219
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 300
Number of HSP's that attempted gapping in prelim test: 4812
Number of HSP's gapped (non-prelim): 1467
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.