BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo sapiens] (359 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [H... 744 0.0 gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H... 738 0.0 gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens] 295 6e-80 gi|188497618 connector enhancer of kinase suppressor of Ras 1 [H... 57 3e-08 gi|11321634 CD2-associated protein [Homo sapiens] 56 6e-08 gi|194733753 phosphoinositide-binding protein PIP3-E isoform 1 [... 54 2e-07 gi|194733747 phosphoinositide-binding protein PIP3-E isoform 1 [... 54 2e-07 gi|40354212 phosphoinositide-binding protein PIP3-E isoform 2 [H... 54 2e-07 gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Ho... 54 2e-07 gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo... 52 6e-07 gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 52 8e-07 gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 52 8e-07 gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Ho... 52 1e-06 gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo... 50 2e-06 gi|154354979 myosin X [Homo sapiens] 50 4e-06 gi|93102364 SWAP-70 protein [Homo sapiens] 49 7e-06 gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens] 47 2e-05 gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens] 47 2e-05 gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens] 47 2e-05 gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens] 47 2e-05 gi|189491778 nephrocystin 1 isoform 4 [Homo sapiens] 47 2e-05 gi|189491776 nephrocystin 1 isoform 3 [Homo sapiens] 47 2e-05 gi|189491774 nephrocystin 1 isoform 2 [Homo sapiens] 47 2e-05 gi|46397398 nephrocystin 1 isoform 1 [Homo sapiens] 47 2e-05 gi|109689723 abl interactor 2 [Homo sapiens] 47 2e-05 gi|224586880 Ras protein-specific guanine nucleotide-releasing f... 47 3e-05 gi|24797099 Ras protein-specific guanine nucleotide-releasing fa... 47 3e-05 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 47 3e-05 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 47 3e-05 gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] 47 3e-05 >gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo sapiens] Length = 359 Score = 744 bits (1922), Expect = 0.0 Identities = 359/359 (100%), Positives = 359/359 (100%) Query: 1 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG 60 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG Sbjct: 1 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG 60 Query: 61 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD 120 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD Sbjct: 61 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD 120 Query: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL Sbjct: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180 Query: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS Sbjct: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240 Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQ 300 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQ Sbjct: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQ 300 Query: 301 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 359 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER Sbjct: 301 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 359 >gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo sapiens] Length = 358 Score = 738 bits (1906), Expect = 0.0 Identities = 358/359 (99%), Positives = 358/359 (99%), Gaps = 1/359 (0%) Query: 1 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG 60 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG Sbjct: 1 MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQG 60 Query: 61 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD 120 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD Sbjct: 61 GDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVKGAQELDNVIKQGYLEKKSKD 120 Query: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL Sbjct: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180 Query: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS Sbjct: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240 Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQ 300 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKG DYASYYQ Sbjct: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKG-DYASYYQ 299 Query: 301 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 359 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER Sbjct: 300 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEER 358 >gi|16753212 src kinase associated phosphoprotein 2 [Homo sapiens] Length = 359 Score = 295 bits (754), Expect = 6e-80 Identities = 159/369 (43%), Positives = 224/369 (60%), Gaps = 40/369 (10%) Query: 6 LPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQGGDIGQ 65 LPEEIR LL D E F+A+ L+ ENLS A++ R+ +++ + +K+ Y +FQ +G Sbjct: 13 LPEEIRNLLADVETFVADILKGENLSKKAKEKRESLIKKIKDVKSIYLQEFQDKGDAEDG 72 Query: 66 DSSDDNHSGTLG-LSLTSDAPFLSDYQDEGMEDIVK----GAQELDNVIKQGYLEKKSKD 120 + DD +G +SL S+ D DE D + AQ+L V+K GYLEK+ KD Sbjct: 73 EEYDDPFAGPPDTISLASER---YDKDDEAPSDGAQFPPIAAQDLPFVLKAGYLEKRRKD 129 Query: 121 HSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFEL 180 HSF G EWQKRWC +S+ +FYYY ++K KQ KG F I GY VRM LR+D KK+ CFE+ Sbjct: 130 HSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYSVRMNNTLRKDGKKDCCFEI 189 Query: 181 TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDS 240 ++ D+R Y+FTA SP +A +WV Q+ F+L+D+ S IP E+ +E+ E YDD+D Sbjct: 190 SAPDKRIYQFTAASPKDAEEWVQQLKFVLQDMESDIIP----EDYDERGELYDDVD---- 241 Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHD-----LEEDESGTR------ 289 P + + +P +++IYE LP+EE D +EE ++ Sbjct: 242 -------HPLPISNPLTSSQPI----DDEIYEELPEEEEDSAPVKVEEQRKMSQDSVHHT 290 Query: 290 --RKGVDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPK 347 K DYA++YQGLWDC G DELSF+RGD+I ILSKEYN YGWWVGE+ +G+VPK Sbjct: 291 SGDKSTDYANFYQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPK 350 Query: 348 EYLTTAFEV 356 Y+ +++ Sbjct: 351 AYIMEMYDI 359 >gi|188497618 connector enhancer of kinase suppressor of Ras 1 [Homo sapiens] Length = 713 Score = 57.0 bits (136), Expect = 3e-08 Identities = 55/238 (23%), Positives = 88/238 (36%), Gaps = 12/238 (5%) Query: 73 SGTLGLSLTSDAPFLSDYQDEGMEDIVK----GAQELDNVIKQGYLEKKSKDHSFFGSEW 128 +GT GL + D + + +G+ + +EL G+L + F G W Sbjct: 358 AGTPGLPESPDKSPVGRKKSKGLATRLSRRRVSCRELGRPDCDGWLLLRKAPGGFMGPRW 417 Query: 129 QKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRRDSKKESCFELTSQDRRSY 188 ++RW V+ Y+Y + ++ +G + Y + D KK+ F+LT + + Sbjct: 418 RRRWFVLKGHTLYWYRQPQDEKAEGLINVSNYSLESG----HDQKKKYVFQLTHDVYKPF 473 Query: 189 EFTATSPAEARDWVDQISFLLKDLSS---LTIPYEEDEEEEEKEETYDDIDGFDSPSCGS 245 F A + + WV + + S P EED E + E DD G S S Sbjct: 474 IFAADTLTDLSMWVRHLITCISKYQSPGRAPPPREEDCYSETEAEDPDDEAGSHSASPSP 533 Query: 246 QCRPTILPGSVG-IKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGL 302 + L G PT+ + E LE G R+ GV Q L Sbjct: 534 AQAGSPLHGDTSPAATPTQRSPRTSFGSLTDSSEEALEGMVRGLRQGGVSLLGQPQPL 591 >gi|11321634 CD2-associated protein [Homo sapiens] Length = 639 Score = 55.8 bits (133), Expect = 6e-08 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 3/99 (3%) Query: 262 TEEKEEED--IYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDELSFQRGD 319 TEEK+ E I + L + +E ++ T K + Y + L+ G DEL+F+ G+ Sbjct: 236 TEEKKPEKPLILQSLGPKTQSVEITKTDTEGK-IKAKEYCRTLFAYEGTNEDELTFKEGE 294 Query: 320 LIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEE 358 +I ++SKE GWW GELN G+ P + E+++ Sbjct: 295 IIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDK 333 Score = 33.5 bits (75), Expect = 0.30 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 2/40 (5%) Query: 311 DELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 350 DEL + GD+I I E GWW G LN+ +G+ P ++ Sbjct: 125 DELELKVGDIIDI--NEEVEEGWWSGTLNNKLGLFPSNFV 162 Score = 30.8 bits (68), Expect = 2.0 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 5/58 (8%) Query: 293 VDYASYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 350 VDY Y D DEL+ + G++IR + K+ GW GELN G+ P ++ Sbjct: 2 VDYIVEY----DYDAVHDDELTIRVGEIIRNV-KKLQEEGWLEGELNGRRGMFPDNFV 54 >gi|194733753 phosphoinositide-binding protein PIP3-E isoform 1 [Homo sapiens] Length = 438 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/127 (23%), Positives = 64/127 (50%), Gaps = 7/127 (5%) Query: 103 QELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGV 162 ++L + QG+L KK + SF ++W+K W ++ Y+Y+N+ +++ G + + V Sbjct: 38 KDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTV 97 Query: 163 RMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIP---Y 219 A + KK+ F+++ +++ F A + E W++++ + S T Y Sbjct: 98 ERA----SECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECY 153 Query: 220 EEDEEEE 226 E E+E+ Sbjct: 154 SESEQED 160 >gi|194733747 phosphoinositide-binding protein PIP3-E isoform 1 [Homo sapiens] Length = 438 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/127 (23%), Positives = 64/127 (50%), Gaps = 7/127 (5%) Query: 103 QELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGV 162 ++L + QG+L KK + SF ++W+K W ++ Y+Y+N+ +++ G + + V Sbjct: 38 KDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTV 97 Query: 163 RMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIP---Y 219 A + KK+ F+++ +++ F A + E W++++ + S T Y Sbjct: 98 ERA----SECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECY 153 Query: 220 EEDEEEE 226 E E+E+ Sbjct: 154 SESEQED 160 >gi|40354212 phosphoinositide-binding protein PIP3-E isoform 2 [Homo sapiens] Length = 437 Score = 54.3 bits (129), Expect = 2e-07 Identities = 30/127 (23%), Positives = 64/127 (50%), Gaps = 7/127 (5%) Query: 103 QELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGV 162 ++L + QG+L KK + SF ++W+K W ++ Y+Y+N+ +++ G + + V Sbjct: 37 KDLGHADCQGWLYKKKEKGSFLSNKWKKFWVILKGSSLYWYSNQMAEKADGFVNLPDFTV 96 Query: 163 RMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIP---Y 219 A + KK+ F+++ +++ F A + E W++++ + S T Y Sbjct: 97 ERA----SECKKKHAFKISHPQIKTFYFAAENVQEMNVWLNKLGSAVIHQESTTKDEECY 152 Query: 220 EEDEEEE 226 E E+E+ Sbjct: 153 SESEQED 159 >gi|41393057 connector enhancer of kinase suppressor of Ras 2 [Homo sapiens] Length = 1034 Score = 54.3 bits (129), Expect = 2e-07 Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 13/141 (9%) Query: 111 QGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPHLRR 170 +G+L KK S+F +W+K W V+ Y+Y NE+ ++ +G + + + A R Sbjct: 574 EGWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKAEGFISLPEFKIDRASECR- 632 Query: 171 DSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEEEEKEE 230 K+ F+ +S+ F A + W+++I+ LT Y E E +++++ Sbjct: 633 ---KKYAFKACHPKIKSFYFAAEHLDDMNRWLNRINM-------LTAGYAERERIKQEQD 682 Query: 231 TYDDID--GFDSPSCGSQCRP 249 + + D D+PS Q P Sbjct: 683 YWSESDKEEADTPSTPKQDSP 703 >gi|227430338 SH3 domain containing, Ysc84-like 1 isoform 2 [Homo sapiens] Length = 323 Score = 52.4 bits (124), Expect = 6e-07 Identities = 33/150 (22%), Positives = 63/150 (42%), Gaps = 12/150 (8%) Query: 207 FLLKDLSSLTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKE 266 F +D+ + I + + + E+ Y+ +D F R + ++ E+ Sbjct: 179 FYCQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQR-------INARKAAREQR 231 Query: 267 EEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQ-----GLWDCHGDQPDELSFQRGDLI 321 + E+ P ++ + + ++ Q L+ G QP +L+FQ GD I Sbjct: 232 KSSAKELPPKPLSRPQQSSAPVQLNSGSQSNLNQPIEVTALYSFEGQQPGDLNFQAGDRI 291 Query: 322 RILSKEYNMYGWWVGELNSLVGIVPKEYLT 351 ++SK + + WW G+L GI P Y+T Sbjct: 292 TVISKTDSHFDWWEGKLRGQTGIFPANYVT 321 >gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo sapiens] Length = 756 Score = 52.0 bits (123), Expect = 8e-07 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 17/110 (15%) Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQ 300 PS G+ P++ PG P + L D + V + Y+ Sbjct: 145 PSLGNPDMPSVSPGPQR-----------------PPKLSSLAYDSPPDYLQTVSHPEVYR 187 Query: 301 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 350 L+D + PDEL+ +RGD++++LSK GWW GE G+ P ++ Sbjct: 188 VLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 237 Score = 35.0 bits (79), Expect = 0.10 Identities = 13/43 (30%), Positives = 26/43 (60%), Gaps = 2/43 (4%) Query: 308 DQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 350 +Q DEL Q G+++ ++ + + GWW+G+ N +G P ++ Sbjct: 97 EQADELKLQAGEIVEMIKEIED--GWWLGKKNGQLGAFPSNFV 137 >gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo sapiens] Length = 645 Score = 52.0 bits (123), Expect = 8e-07 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 17/110 (15%) Query: 241 PSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQ 300 PS G+ P++ PG P + L D + V + Y+ Sbjct: 34 PSLGNPDMPSVSPGPQR-----------------PPKLSSLAYDSPPDYLQTVSHPEVYR 76 Query: 301 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 350 L+D + PDEL+ +RGD++++LSK GWW GE G+ P ++ Sbjct: 77 VLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 126 >gi|52421790 mitogen-activated protein kinase kinase kinase 9 [Homo sapiens] Length = 1118 Score = 51.6 bits (122), Expect = 1e-06 Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 8/83 (9%) Query: 277 EEHDLEEDES----GTRRKGVDYA-SYYQGLWDCHGDQPDELSFQRGDLIRILSKEYNMY 331 EE + EE+E+ G G D Y+ +++ DEL+ + GD++ +LSK+ + Sbjct: 30 EEEEEEEEEAAAAVGPGELGCDAPLPYWTAVFEYEAAGEDELTLRLGDVVEVLSKDSQVS 89 Query: 332 G---WWVGELNSLVGIVPKEYLT 351 G WW G+LN VGI P Y+T Sbjct: 90 GDEGWWTGQLNQRVGIFPSNYVT 112 >gi|227430336 SH3 domain containing, Ysc84-like 1 isoform 1 [Homo sapiens] Length = 342 Score = 50.4 bits (119), Expect = 2e-06 Identities = 21/50 (42%), Positives = 30/50 (60%) Query: 302 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLT 351 L+ G QP +L+FQ GD I ++SK + + WW G+L GI P Y+T Sbjct: 291 LYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVT 340 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 49.7 bits (117), Expect = 4e-06 Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 7/99 (7%) Query: 109 IKQGYLEKKSKDHSFFGSE-WQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAPH 167 +KQG+L KK S W+KRW V+ + Y+ N+ ++ KGT VR A Sbjct: 1214 LKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGT-----VEVRTAKE 1268 Query: 168 LRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQIS 206 + ++ KE+ ++ D R++ A SP +A W +S Sbjct: 1269 IIDNTTKENGIDIIMAD-RTFHLIAESPEDASQWFSVLS 1306 >gi|93102364 SWAP-70 protein [Homo sapiens] Length = 585 Score = 48.9 bits (115), Expect = 7e-06 Identities = 33/124 (26%), Positives = 57/124 (45%), Gaps = 9/124 (7%) Query: 107 NVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLI-KGYGVRMA 165 +V+KQGY+ KK W +RW V+ + YY +E K KG L+ + V Sbjct: 210 DVLKQGYMMKKGHRRK----NWTERWFVLKPNIISYYVSEDLKDKKGDILLDENCCVESL 265 Query: 166 PHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQISFLLKDLSSLTIPYEEDEEE 225 P +D KK C L +++E +A+ + ++W+ I + L + P ++ + Sbjct: 266 PD--KDGKK--CLFLVKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKEARQ 321 Query: 226 EEKE 229 KE Sbjct: 322 RRKE 325 >gi|224994221 SH3-domain binding protein 2 isoform b [Homo sapiens] Length = 618 Score = 47.4 bits (111), Expect = 2e-05 Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 30/190 (15%) Query: 101 GAQEL----DNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFL 156 GAQ L V K GYL KK +W R+ ++ + YY+ + S P+G F Sbjct: 73 GAQNLLTMPGGVAKAGYLHKKGGTQLQL-LKWPLRFVIIHKRCVYYFKSSTSASPQGAFS 131 Query: 157 IKGYGVRMAPHLRRDSKKESCFEL--TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSS 214 + GY M S F++ S+ R++ F+A+S E + W ++ L +++ Sbjct: 132 LSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSW---MALLRREIGH 188 Query: 215 LTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVL 274 +E+ + + ++ D D F G+ RP + S PT+ + Sbjct: 189 F---HEKKDLPLDTSDSSSDTDSF----YGAVERPVDISLS---PYPTDNE--------- 229 Query: 275 PDEEHDLEED 284 D EHD E+D Sbjct: 230 -DYEHDDEDD 238 >gi|224994219 SH3-domain binding protein 2 isoform c [Homo sapiens] Length = 589 Score = 47.4 bits (111), Expect = 2e-05 Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 30/190 (15%) Query: 101 GAQEL----DNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFL 156 GAQ L V K GYL KK +W R+ ++ + YY+ + S P+G F Sbjct: 44 GAQNLLTMPGGVAKAGYLHKKGGTQLQL-LKWPLRFVIIHKRCVYYFKSSTSASPQGAFS 102 Query: 157 IKGYGVRMAPHLRRDSKKESCFEL--TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSS 214 + GY M S F++ S+ R++ F+A+S E + W ++ L +++ Sbjct: 103 LSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSW---MALLRREIGH 159 Query: 215 LTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVL 274 +E+ + + ++ D D F G+ RP + S PT+ + Sbjct: 160 F---HEKKDLPLDTSDSSSDTDSF----YGAVERPVDISLS---PYPTDNE--------- 200 Query: 275 PDEEHDLEED 284 D EHD E+D Sbjct: 201 -DYEHDDEDD 209 >gi|170014705 SH3-domain binding protein 2 isoform a [Homo sapiens] Length = 561 Score = 47.4 bits (111), Expect = 2e-05 Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 30/190 (15%) Query: 101 GAQEL----DNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFL 156 GAQ L V K GYL KK +W R+ ++ + YY+ + S P+G F Sbjct: 16 GAQNLLTMPGGVAKAGYLHKKGGTQLQL-LKWPLRFVIIHKRCVYYFKSSTSASPQGAFS 74 Query: 157 IKGYGVRMAPHLRRDSKKESCFEL--TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSS 214 + GY M S F++ S+ R++ F+A+S E + W ++ L +++ Sbjct: 75 LSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSW---MALLRREIGH 131 Query: 215 LTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVL 274 +E+ + + ++ D D F G+ RP + S PT+ + Sbjct: 132 F---HEKKDLPLDTSDSSSDTDSF----YGAVERPVDISLS---PYPTDNE--------- 172 Query: 275 PDEEHDLEED 284 D EHD E+D Sbjct: 173 -DYEHDDEDD 181 >gi|170014703 SH3-domain binding protein 2 isoform a [Homo sapiens] Length = 561 Score = 47.4 bits (111), Expect = 2e-05 Identities = 48/190 (25%), Positives = 81/190 (42%), Gaps = 30/190 (15%) Query: 101 GAQEL----DNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFL 156 GAQ L V K GYL KK +W R+ ++ + YY+ + S P+G F Sbjct: 16 GAQNLLTMPGGVAKAGYLHKKGGTQLQL-LKWPLRFVIIHKRCVYYFKSSTSASPQGAFS 74 Query: 157 IKGYGVRMAPHLRRDSKKESCFEL--TSQDRRSYEFTATSPAEARDWVDQISFLLKDLSS 214 + GY M S F++ S+ R++ F+A+S E + W ++ L +++ Sbjct: 75 LSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSW---MALLRREIGH 131 Query: 215 LTIPYEEDEEEEEKEETYDDIDGFDSPSCGSQCRPTILPGSVGIKEPTEEKEEEDIYEVL 274 +E+ + + ++ D D F G+ RP + S PT+ + Sbjct: 132 F---HEKKDLPLDTSDSSSDTDSF----YGAVERPVDISLS---PYPTDNE--------- 172 Query: 275 PDEEHDLEED 284 D EHD E+D Sbjct: 173 -DYEHDDEDD 181 >gi|189491778 nephrocystin 1 isoform 4 [Homo sapiens] Length = 614 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 16/108 (14%) Query: 261 PTEEKEEEDIY---------EVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPD 311 PTEE+EE + E +EE + EE+ES G +Y + + D Q Sbjct: 52 PTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIA----VGDFTAQQVG 107 Query: 312 ELSFQRGDLIRILSKEYNMYGWWVG-ELNSLVGIVPKEYLTTAFEVEE 358 +L+F++G+++ ++ K+ + GWW+ + G+VP+ YL E EE Sbjct: 108 DLTFKKGEILLVIEKKPD--GWWIAKDAKGNEGLVPRTYLEPYSEEEE 153 >gi|189491776 nephrocystin 1 isoform 3 [Homo sapiens] Length = 677 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 16/108 (14%) Query: 261 PTEEKEEEDIY---------EVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPD 311 PTEE+EE + E +EE + EE+ES G +Y + + D Q Sbjct: 114 PTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIA----VGDFTAQQVG 169 Query: 312 ELSFQRGDLIRILSKEYNMYGWWVG-ELNSLVGIVPKEYLTTAFEVEE 358 +L+F++G+++ ++ K+ + GWW+ + G+VP+ YL E EE Sbjct: 170 DLTFKKGEILLVIEKKPD--GWWIAKDAKGNEGLVPRTYLEPYSEEEE 215 >gi|189491774 nephrocystin 1 isoform 2 [Homo sapiens] Length = 732 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 16/108 (14%) Query: 261 PTEEKEEEDIY---------EVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPD 311 PTEE+EE + E +EE + EE+ES G +Y + + D Q Sbjct: 114 PTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIA----VGDFTAQQVG 169 Query: 312 ELSFQRGDLIRILSKEYNMYGWWVG-ELNSLVGIVPKEYLTTAFEVEE 358 +L+F++G+++ ++ K+ + GWW+ + G+VP+ YL E EE Sbjct: 170 DLTFKKGEILLVIEKKPD--GWWIAKDAKGNEGLVPRTYLEPYSEEEE 215 >gi|46397398 nephrocystin 1 isoform 1 [Homo sapiens] Length = 733 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 16/108 (14%) Query: 261 PTEEKEEEDIY---------EVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPD 311 PTEE+EE + E +EE + EE+ES G +Y + + D Q Sbjct: 114 PTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIA----VGDFTAQQVG 169 Query: 312 ELSFQRGDLIRILSKEYNMYGWWVG-ELNSLVGIVPKEYLTTAFEVEE 358 +L+F++G+++ ++ K+ + GWW+ + G+VP+ YL E EE Sbjct: 170 DLTFKKGEILLVIEKKPD--GWWIAKDAKGNEGLVPRTYLEPYSEEEE 215 >gi|109689723 abl interactor 2 [Homo sapiens] Length = 475 Score = 47.4 bits (111), Expect = 2e-05 Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 6/98 (6%) Query: 261 PTEEKEEEDIYEVLPDEEHDLEEDESGTRRKGVDYASYYQGLWDCHGDQPDELSFQRGDL 320 P E+ EEE+ V + + EED R Y ++D D+ DELSFQ G + Sbjct: 384 PPEDYEEEEAAVVEYSDPY-AEEDPPWAPRS---YLEKVVAIYDYTKDKEDELSFQEGAI 439 Query: 321 IRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVEE 358 I ++ K N GW+ G +N + G+ P Y+ + E Sbjct: 440 IYVIKK--NDDGWYEGVMNGVTGLFPGNYVESIMHYSE 475 >gi|224586880 Ras protein-specific guanine nucleotide-releasing factor 1 isoform 3 [Homo sapiens] Length = 1257 Score = 46.6 bits (109), Expect = 3e-05 Identities = 24/105 (22%), Positives = 53/105 (50%), Gaps = 12/105 (11%) Query: 110 KQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAP--- 166 ++GYL K+S D++ +WQ +W + + L +Y+ ++ S +P G +L++G AP Sbjct: 25 RKGYLSKRSSDNT----KWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGCVCDRAPSPK 80 Query: 167 ---HLRRDSKKESCF--ELTSQDRRSYEFTATSPAEARDWVDQIS 206 + +K+ F + +++++ E + +WV I+ Sbjct: 81 PALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEWVAAIA 125 >gi|24797099 Ras protein-specific guanine nucleotide-releasing factor 1 isoform 1 [Homo sapiens] Length = 1273 Score = 46.6 bits (109), Expect = 3e-05 Identities = 24/105 (22%), Positives = 53/105 (50%), Gaps = 12/105 (11%) Query: 110 KQGYLEKKSKDHSFFGSEWQKRWCVVSRGLFYYYANEKSKQPKGTFLIKGYGVRMAP--- 166 ++GYL K+S D++ +WQ +W + + L +Y+ ++ S +P G +L++G AP Sbjct: 25 RKGYLSKRSSDNT----KWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGCVCDRAPSPK 80 Query: 167 ---HLRRDSKKESCF--ELTSQDRRSYEFTATSPAEARDWVDQIS 206 + +K+ F + +++++ E + +WV I+ Sbjct: 81 PALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEWVAAIA 125 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 46.6 bits (109), Expect = 3e-05 Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Query: 301 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVE 357 G++D DEL+F +G +I +L+KE WW GE+N VG+ P Y+ +++ Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDP--DWWKGEVNGQVGLFPSNYVKLTTDMD 1216 Score = 34.3 bits (77), Expect = 0.18 Identities = 13/49 (26%), Positives = 26/49 (53%), Gaps = 3/49 (6%) Query: 302 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 350 ++ + +L+FQ+GD+I + K+ + WW G + G+ P Y+ Sbjct: 1010 MYTYESSEQGDLTFQQGDVILVTKKDGD---WWTGTVGDKAGVFPSNYV 1055 Score = 32.7 bits (73), Expect = 0.52 Identities = 15/51 (29%), Positives = 26/51 (50%), Gaps = 3/51 (5%) Query: 300 QGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 350 Q L+ + + L+F + D+I +L ++ WW GE+ G PK Y+ Sbjct: 919 QALYPWRAKKDNHLNFNKNDVITVLEQQDM---WWFGEVQGQKGWFPKSYV 966 Score = 30.8 bits (68), Expect = 2.0 Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 5/57 (8%) Query: 298 YYQGLWDCHGDQPDELSFQRGDLIRILSK-----EYNMYGWWVGELNSLVGIVPKEY 349 YY+ L+ DE++ Q GD++ + + + GW GEL G P Y Sbjct: 744 YYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANY 800 Score = 28.9 bits (63), Expect = 7.5 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 7/46 (15%) Query: 310 PDELSFQRGDLIRILSKEYNMYGWWVGELNS-----LVGIVPKEYL 350 P++L+ G LI I K N GWW GEL + +G P Y+ Sbjct: 1090 PEQLTLAPGQLILIRKK--NPGGWWEGELQARGKKRQIGWFPANYV 1133 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 46.6 bits (109), Expect = 3e-05 Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 2/57 (3%) Query: 301 GLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYLTTAFEVE 357 G++D DEL+F +G +I +L+KE WW GE+N VG+ P Y+ +++ Sbjct: 1162 GMYDYTAQNDDELAFNKGQIINVLNKEDP--DWWKGEVNGQVGLFPSNYVKLTTDMD 1216 Score = 34.3 bits (77), Expect = 0.18 Identities = 13/49 (26%), Positives = 26/49 (53%), Gaps = 3/49 (6%) Query: 302 LWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 350 ++ + +L+FQ+GD+I + K+ + WW G + G+ P Y+ Sbjct: 1010 MYTYESSEQGDLTFQQGDVILVTKKDGD---WWTGTVGDKAGVFPSNYV 1055 Score = 32.7 bits (73), Expect = 0.52 Identities = 15/51 (29%), Positives = 26/51 (50%), Gaps = 3/51 (5%) Query: 300 QGLWDCHGDQPDELSFQRGDLIRILSKEYNMYGWWVGELNSLVGIVPKEYL 350 Q L+ + + L+F + D+I +L ++ WW GE+ G PK Y+ Sbjct: 919 QALYPWRAKKDNHLNFNKNDVITVLEQQDM---WWFGEVQGQKGWFPKSYV 966 Score = 30.8 bits (68), Expect = 2.0 Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 5/57 (8%) Query: 298 YYQGLWDCHGDQPDELSFQRGDLIRILSK-----EYNMYGWWVGELNSLVGIVPKEY 349 YY+ L+ DE++ Q GD++ + + + GW GEL G P Y Sbjct: 744 YYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANY 800 Score = 28.9 bits (63), Expect = 7.5 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 7/46 (15%) Query: 310 PDELSFQRGDLIRILSKEYNMYGWWVGELNS-----LVGIVPKEYL 350 P++L+ G LI I K N GWW GEL + +G P Y+ Sbjct: 1090 PEQLTLAPGQLILIRKK--NPGGWWEGELQARGKKRQIGWFPANYV 1133 >gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens] Length = 1090 Score = 46.6 bits (109), Expect = 3e-05 Identities = 27/69 (39%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Query: 283 EDESGTRRKGVDYASYYQGLWDCHGDQPDELSFQRGDLIRIL-SKEYNMYGWWVGELNSL 341 +++ G KGV YA LWD DELSF GD + IL K+ + WW L Sbjct: 1013 QEKLGVMNKGVAYA-----LWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDR 1067 Query: 342 VGIVPKEYL 350 G VPK L Sbjct: 1068 EGYVPKNLL 1076 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.135 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,189,109 Number of Sequences: 37866 Number of extensions: 781460 Number of successful extensions: 7195 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 159 Number of HSP's successfully gapped in prelim test: 295 Number of HSP's that attempted gapping in prelim test: 4726 Number of HSP's gapped (non-prelim): 1504 length of query: 359 length of database: 18,247,518 effective HSP length: 103 effective length of query: 256 effective length of database: 14,347,320 effective search space: 3672913920 effective search space used: 3672913920 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.