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Search of human proteins with 224809327
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
(457 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 924 0.0
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 924 0.0
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 924 0.0
gi|4503729 FK506 binding protein 52 [Homo sapiens] 519 e-147
gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens] 458 e-129
gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo sa... 101 2e-21
gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens] 100 3e-21
gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens] 100 3e-21
gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo sapi... 99 6e-21
gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 99 6e-21
gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 99 6e-21
gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens] 90 4e-18
gi|192448443 FK506 binding protein 10 [Homo sapiens] 85 1e-16
gi|4826932 peptidylprolyl isomerase D [Homo sapiens] 83 5e-16
gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens] 83 5e-16
gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens] 82 8e-16
gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens] 81 2e-15
gi|33469985 FK506 binding protein 9 [Homo sapiens] 80 4e-15
gi|52630440 FK506-binding protein 8 [Homo sapiens] 79 7e-15
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 76 6e-14
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 76 7e-14
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 76 7e-14
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 75 1e-13
gi|206725547 FK506 binding protein 7 isoform b precursor [Homo s... 72 1e-12
gi|31317231 FK506 binding protein 7 isoform a precursor [Homo sa... 69 1e-11
gi|27262638 sperm associated antigen 1 [Homo sapiens] 67 3e-11
gi|27262636 sperm associated antigen 1 [Homo sapiens] 67 3e-11
gi|74272280 aryl hydrocarbon receptor interacting protein-like 1... 66 6e-11
gi|74272278 aryl hydrocarbon receptor interacting protein-like 1... 66 6e-11
gi|74272276 aryl hydrocarbon receptor interacting protein-like 1... 66 6e-11
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 924 bits (2388), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
Sbjct: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
Sbjct: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240
Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300
LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
Sbjct: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300
Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360
EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
Sbjct: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360
Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420
QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
Sbjct: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420
Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
Sbjct: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 924 bits (2388), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
Sbjct: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
Sbjct: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240
Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300
LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
Sbjct: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300
Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360
EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
Sbjct: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360
Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420
QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
Sbjct: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420
Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
Sbjct: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 924 bits (2388), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
Sbjct: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
Sbjct: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240
Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300
LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
Sbjct: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300
Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360
EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
Sbjct: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360
Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420
QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
Sbjct: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420
Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
Sbjct: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 519 bits (1336), Expect = e-147
Identities = 252/454 (55%), Positives = 340/454 (74%), Gaps = 11/454 (2%)
Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
MT +E + +A + +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G
Sbjct: 1 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 60
Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P
Sbjct: 61 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 120
Query: 121 KIPSNATLFFEIELLDFKGEDLFE--DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 178
KIP NATL FE+EL +FKGEDL E DGGIIRR + +GEGY+ PNEGA VE+ LEG
Sbjct: 121 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 180
Query: 179 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 238
++FD R++ F +GEGE+ D+P G+++A+++M++ E I+YL P Y FG GK KF I PN
Sbjct: 181 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 240
Query: 239 AELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL 298
AEL YE+ LKSFEKAKESWEM+++EKLEQ+ IVKE+GTVYFK GKY QA++QY KIVSWL
Sbjct: 241 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 300
Query: 299 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 358
E E S +E++ +++ LA+ LNLAMC+LKL+ ++ A+E C+KAL LDS NEKGL+RRG
Sbjct: 301 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 360
Query: 359 EAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 418
EA L +N+FE A+ DF+KVL++ P NKAA+ Q+++CQ++ + R++++YANMF++ AE
Sbjct: 361 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 420
Query: 419 QDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEK 452
++ K +A + G + TD++ EE+K
Sbjct: 421 EENKAKAEASSG---------DHPTDTEMKEEQK 445
>gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]
Length = 268
Score = 458 bits (1178), Expect = e-129
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
Sbjct: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
Query: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
Sbjct: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPR 222
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPR
Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPR 222
Score = 52.4 bits (124), Expect = 9e-07
Identities = 39/123 (31%), Positives = 61/123 (49%), Gaps = 14/123 (11%)
Query: 138 KGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCG-GRMFDC-----RDVAFT 189
+GED+ +D G+++ KR G G P G V +H +G+ G+ FD F+
Sbjct: 21 QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 80
Query: 190 VGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGK-PKFGIEPNAELIYEVTLK 248
+G+G+ + D + M++ E C L P Y +G AG PK I NA L +E+ L
Sbjct: 81 LGKGQ---VIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPK--IPSNATLFFEIELL 135
Query: 249 SFE 251
F+
Sbjct: 136 DFK 138
>gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo
sapiens]
Length = 108
Score = 101 bits (251), Expect = 2e-21
Identities = 49/98 (50%), Positives = 62/98 (63%)
Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100
G+G P G VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ G A M G
Sbjct: 11 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLG 70
Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138
+ L C P+ AYG+ G IP NATL F++ELL+ +
Sbjct: 71 QRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 108
Score = 39.7 bits (91), Expect = 0.006
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 10/111 (9%)
Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200
G+ T G+G + P +G T +H G G+ FD + F +G+ E +
Sbjct: 2 GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQE---VIK 58
Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251
G ++ +M ++ L P +G G P I PNA LI++V L + E
Sbjct: 59 GFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGV-IPPNATLIFDVELLNLE 108
>gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 100 bits (249), Expect = 3e-21
Identities = 49/95 (51%), Positives = 61/95 (64%)
Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100
G+G P G VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ GVA M G
Sbjct: 11 GDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVG 70
Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
+ L P+YAYG+ G IP +ATL F++ELL
Sbjct: 71 QRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL 105
Score = 40.0 bits (92), Expect = 0.004
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 10/111 (9%)
Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200
G+ T G+G + P G T +H G G+ FD + F +G+ E +
Sbjct: 2 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQE---VIR 58
Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251
G ++ + +M ++ L + P Y +G G P I P+A L+++V L E
Sbjct: 59 GWEEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 108
>gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 100 bits (249), Expect = 3e-21
Identities = 49/95 (51%), Positives = 61/95 (64%)
Query: 41 GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100
G+G P G VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ GVA M G
Sbjct: 11 GDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVG 70
Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
+ L P+YAYG+ G IP +ATL F++ELL
Sbjct: 71 QRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL 105
Score = 40.0 bits (92), Expect = 0.004
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 10/111 (9%)
Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200
G+ T G+G + P G T +H G G+ FD + F +G+ E +
Sbjct: 2 GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQE---VIR 58
Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251
G ++ + +M ++ L + P Y +G G P I P+A L+++V L E
Sbjct: 59 GWEEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 108
>gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo
sapiens]
Length = 142
Score = 99.4 bits (246), Expect = 6e-21
Identities = 51/100 (51%), Positives = 65/100 (65%)
Query: 36 IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
+ KRV + GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+
Sbjct: 35 VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
Query: 96 TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
M +GE L+ E YG G+ PKIP ATL FE+ELL
Sbjct: 95 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
>gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 99.4 bits (246), Expect = 6e-21
Identities = 51/100 (51%), Positives = 65/100 (65%)
Query: 36 IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
+ KRV + GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+
Sbjct: 35 VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
Query: 96 TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
M +GE L+ E YG G+ PKIP ATL FE+ELL
Sbjct: 95 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
>gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 99.4 bits (246), Expect = 6e-21
Identities = 51/100 (51%), Positives = 65/100 (65%)
Query: 36 IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
+ KRV + GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+
Sbjct: 35 VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
Query: 96 TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
M +GE L+ E YG G+ PKIP ATL FE+ELL
Sbjct: 95 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
>gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens]
Length = 349
Score = 90.1 bits (222), Expect = 4e-18
Identities = 74/249 (29%), Positives = 113/249 (45%), Gaps = 25/249 (10%)
Query: 145 DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIG--I 202
DG +++ +G G P G+ + G G T+G G + G I
Sbjct: 101 DGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELI 160
Query: 203 DKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTK 262
+K LE M + E+ L L G +G P +TL SF + ++SWE++T
Sbjct: 161 EKCLESMCQGEEAELQLP-----GHSGPP-----------VRLTLASFTQGRDSWELETS 204
Query: 263 EKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLN 322
EK A + +GT F+ G A YG+ + L L+ E +L A N
Sbjct: 205 EKEALAREERARGTELFRAGNPEGAARCYGRALRLL-----LTLPPPGPPERTVLHA--N 257
Query: 323 LAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382
LA C L L + A + CD+ L + + K LYRRG AQ + E A D +KVL ++P
Sbjct: 258 LAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDP 317
Query: 383 QNKAARLQI 391
+N+AA+ ++
Sbjct: 318 KNRAAQEEL 326
>gi|192448443 FK506 binding protein 10 [Homo sapiens]
Length = 582
Score = 85.1 bits (209), Expect = 1e-16
Identities = 68/223 (30%), Positives = 100/223 (44%), Gaps = 17/223 (7%)
Query: 49 IGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCK 108
+GD V HY G +GKKFDSS+DRN +G G++I D G+ M E L+
Sbjct: 61 MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120
Query: 109 PEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATV 168
P YGS G IP +ATL+F++ LLD + ED + R +G V
Sbjct: 121 PHLGYGSIGLAGLIPPDATLYFDVVLLDVWNK---EDTVQVSTLLRPPHCPRMVQDGDFV 177
Query: 169 EIHLEGR-CGGRMFDCRDVAFTVGEGEDHDIPI-------GIDKALEKMQREEQCILYLG 220
H G G FD + +G +D + G+D+ L M E+ + +
Sbjct: 178 RYHYNGTLLDGTSFDT-----SYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIP 232
Query: 221 PRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKE 263
P +GE G I P A L++ V L K++ +++T E
Sbjct: 233 PFLAYGEKGYGTV-IPPQASLVFHVLLIDVHNPKDAVQLETLE 274
Score = 77.8 bits (190), Expect = 2e-14
Identities = 74/267 (27%), Positives = 114/267 (42%), Gaps = 22/267 (8%)
Query: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
D+ + KD L+ ++ GD + HY G L +G FDSS+ RN + +G+
Sbjct: 260 DVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQ 319
Query: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG-EDL 142
G +I D G+ GE + P AYG G+ KIP +A L F + ++DF D+
Sbjct: 320 GYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADV 379
Query: 143 FEDGGIIRRTKRKGEGYSNPNE-GATVEIHLEGRC--GGRMFDCRDVA----FTVGEGED 195
E IR R E + + G V H G ++F D T+G +
Sbjct: 380 VE----IRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANK- 434
Query: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255
+ G+D L+ M E+ L + P GE+G G+ +A L++EV L S E
Sbjct: 435 --VIEGLDTGLQGMCVGERRQLIVPPHLAHGESGAR--GVPGSAVLLFEVELVSREDGLP 490
Query: 256 S-----WEMDTKEKLEQAAIVKEKGTV 277
+ W D L + + + G V
Sbjct: 491 TGYLFVWHKDPPANLFEDMDLNKDGEV 517
Score = 69.7 bits (169), Expect = 5e-12
Identities = 67/249 (26%), Positives = 105/249 (42%), Gaps = 23/249 (9%)
Query: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
D+ +K+D + + R + GD V HY G L +G FD+S+ + + +G
Sbjct: 148 DVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGS 207
Query: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG---- 139
G +IK D G+ M GE ++ P AYG G IP A+L F + L+D
Sbjct: 208 GWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDA 267
Query: 140 ---EDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFD---CRDVAFTVGE 192
E L G +RR G + H G G +FD R+ +
Sbjct: 268 VQLETLELPPGCVRRA----------GAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYI 317
Query: 193 GEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK 252
G+ + IP G+D+ L+ E+ + + P +GE G I +A LI+ V + F
Sbjct: 318 GQGYIIP-GMDQGLQGACMGERRRITIPPHLAYGENGTGD-KIPGSAVLIFNVHVIDFHN 375
Query: 253 AKESWEMDT 261
+ E+ T
Sbjct: 376 PADVVEIRT 384
>gi|4826932 peptidylprolyl isomerase D [Homo sapiens]
Length = 370
Score = 83.2 bits (204), Expect = 5e-16
Identities = 39/144 (27%), Positives = 79/144 (54%), Gaps = 1/144 (0%)
Query: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKAS-ESFLLAAFLNLAMCYLK 329
+K G +FK + A+ +Y +++ +++ + E +A + L+ LN+ C LK
Sbjct: 226 LKNIGNTFFKSQNWEMAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACKLK 285
Query: 330 LREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARL 389
+ + A++ C +AL LD +N K LYRR + + E++ A D +K + P++KA +
Sbjct: 286 MSNWQGAIDSCLEALELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQGIAPEDKAIQA 345
Query: 390 QISMCQKKAKEHNERDRRIYANMF 413
++ ++K K ++++ +YA MF
Sbjct: 346 ELLKVKQKIKAQKDKEKAVYAKMF 369
>gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens]
Length = 327
Score = 83.2 bits (204), Expect = 5e-16
Identities = 50/137 (36%), Positives = 76/137 (55%), Gaps = 4/137 (2%)
Query: 4 DEGAKNNEESPTATVAEQGED--ITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKL 61
++G +++P ++ E+ + DRGVLK V R G G+ V V Y G L
Sbjct: 7 NQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDAS-VLVKYSGYL 65
Query: 62 SN-GKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
+ + FDS++ R P + LG+ + ++G+ +M++GE+ L KP YAYG+ G P
Sbjct: 66 EHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPP 125
Query: 121 KIPSNATLFFEIELLDF 137
IP N T+ FEIELLDF
Sbjct: 126 LIPPNTTVLFEIELLDF 142
Score = 78.2 bits (191), Expect = 1e-14
Identities = 71/291 (24%), Positives = 127/291 (43%), Gaps = 24/291 (8%)
Query: 141 DLFEDGGIIRRTKRKGEG-YSNPNEGATVEI-----HLEGRCGGRMFDCRDVAFTVGEGE 194
D+ D G+++ R+G G P+ V+ H++ F +GE
Sbjct: 31 DISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGE-- 88
Query: 195 DHDIPI-GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKA 253
DI + G++ L M+R E P Y +G G P I PN +++E+ L F
Sbjct: 89 --DITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIELLDFLDC 145
Query: 254 KESW-----------EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEY 302
ES + ++ L+ AA +E G F+ ++ A ++Y + + L
Sbjct: 146 AESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRS 205
Query: 303 GLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQL 362
E E E+ L LNL+ YLKL T A+ ++AL +D N K L+R G+A L
Sbjct: 206 APPE-EQHLVEAAKLPVLLNLSFTYLKLDRPTIALCYGEQALIIDQKNAKALFRCGQACL 264
Query: 363 LMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMF 413
L+ E++ A+ + + P N ++ +++ ++++ ++ MF
Sbjct: 265 LLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMF 315
>gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens]
Length = 322
Score = 82.4 bits (202), Expect = 8e-16
Identities = 47/109 (43%), Positives = 64/109 (58%), Gaps = 2/109 (1%)
Query: 30 DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSN-GKKFDSSHDRNEPFVFSLGKGQVIK 88
DRGVLK V R G G+ V V Y G L + + FDS++ R P + LG+ +
Sbjct: 30 DRGVLKDVIREGAGDLVAPDAS-VLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLW 88
Query: 89 AWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF 137
++G+ +M++GE+ L KP YAYG+ G P IP N T+ FEIELLDF
Sbjct: 89 GMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDF 137
Score = 78.2 bits (191), Expect = 1e-14
Identities = 71/291 (24%), Positives = 127/291 (43%), Gaps = 24/291 (8%)
Query: 141 DLFEDGGIIRRTKRKGEG-YSNPNEGATVEI-----HLEGRCGGRMFDCRDVAFTVGEGE 194
D+ D G+++ R+G G P+ V+ H++ F +GE
Sbjct: 26 DISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGE-- 83
Query: 195 DHDIPI-GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKA 253
DI + G++ L M+R E P Y +G G P I PN +++E+ L F
Sbjct: 84 --DITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIELLDFLDC 140
Query: 254 KESW-----------EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEY 302
ES + ++ L+ AA +E G F+ ++ A ++Y + + L
Sbjct: 141 AESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRS 200
Query: 303 GLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQL 362
E E E+ L LNL+ YLKL T A+ ++AL +D N K L+R G+A L
Sbjct: 201 APPE-EQHLVEAAKLPVLLNLSFTYLKLDRPTIALCYGEQALIIDQKNAKALFRCGQACL 259
Query: 363 LMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMF 413
L+ E++ A+ + + P N ++ +++ ++++ ++ MF
Sbjct: 260 LLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMF 310
>gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]
Length = 224
Score = 80.9 bits (198), Expect = 2e-15
Identities = 52/140 (37%), Positives = 72/140 (51%), Gaps = 11/140 (7%)
Query: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG 64
+ K NE+ P T +E+ D K K V + G+ P GD V+ Y G L +G
Sbjct: 86 KNVKLNEDKPKETKSEETLDEGPPK---YTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDG 142
Query: 65 KKFDSSHDRN-------EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG 117
FD++ + +P F +G G+VI+ WD + TM KGE L +PE+AYG G
Sbjct: 143 TVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKG 202
Query: 118 SL-PKIPSNATLFFEIELLD 136
KIP NA L FE+EL+D
Sbjct: 203 QPDAKIPPNAKLTFEVELVD 222
Score = 45.1 bits (105), Expect = 1e-04
Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 18/125 (14%)
Query: 138 KGEDLFEDGG--IIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFD------------ 182
K E+ ++G + +KG+ + P +G V G G +FD
Sbjct: 99 KSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKN 158
Query: 183 CRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELI 242
+ ++F VG G+ + G D+AL M + E+ L + P + +G+ G+P I PNA+L
Sbjct: 159 AKPLSFKVGVGK---VIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLT 215
Query: 243 YEVTL 247
+EV L
Sbjct: 216 FEVEL 220
>gi|33469985 FK506 binding protein 9 [Homo sapiens]
Length = 570
Score = 80.1 bits (196), Expect = 4e-15
Identities = 70/230 (30%), Positives = 100/230 (43%), Gaps = 9/230 (3%)
Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKP 109
GD V HY G +G+KFDSS+DR+ F +GKGQ+I D + M E + P
Sbjct: 54 GDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPP 113
Query: 110 EYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVE 169
+ AYG+ G IP N+ L F++ L+D ED I + V
Sbjct: 114 KLAYGNEGVSGVIPPNSVLHFDVLLMDIWNS---EDQVQIHTYFKPPSCPRTIQVSDFVR 170
Query: 170 IHLEGR-CGGRMFDC---RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGF 225
H G G +FD R + G IP G+DK L M E+ I+ + P +
Sbjct: 171 YHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIP-GMDKGLLGMCVGEKRIITIPPFLAY 229
Query: 226 GEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKG 275
GE G K I A L+++V L K+S ++ K E + + G
Sbjct: 230 GEDGDGK-DIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSG 278
Score = 77.4 bits (189), Expect = 2e-14
Identities = 68/259 (26%), Positives = 116/259 (44%), Gaps = 16/259 (6%)
Query: 24 DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
DI + +D+ + + + T + D V HY G +G FDSSH+R + + +G
Sbjct: 140 DIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGI 199
Query: 84 GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF---KGE 140
G +I D G+ M GE + P AYG G IP A+L F++ LLD K
Sbjct: 200 GWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDS 259
Query: 141 DLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFD---CRDVAFTVGEGEDH 196
E+ + +R + G + H G G +FD R+ F G+ +
Sbjct: 260 ISIENKVVPENCERISQ------SGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGY 313
Query: 197 DIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKES 256
IP G+D+ L + E+ + + P G+GE G+ I +A L++++ + F +S
Sbjct: 314 VIP-GMDEGLLGVCIGEKRRIVVPPHLGYGEEGRG--NIPGSAVLVFDIHVIDFHNPSDS 370
Query: 257 WEMDTKEKLEQAAIVKEKG 275
+ + K +++ +KG
Sbjct: 371 ISITSHYKPPDCSVLSKKG 389
Score = 70.5 bits (171), Expect = 3e-12
Identities = 58/212 (27%), Positives = 94/212 (44%), Gaps = 14/212 (6%)
Query: 42 NGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGE 101
N E GD + HY G L +G FDSS+ RN F +G+G VI D G+ + GE
Sbjct: 270 NCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGE 329
Query: 102 ICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSN 161
++ P YG G IP +A L F+I ++DF D I + +
Sbjct: 330 KRRIVVPPHLGYGEEGR-GNIPGSAVLVFDIHVIDFHNPS---DSISITSHYKPPDCSVL 385
Query: 162 PNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKALEKMQREEQC 215
+G ++ H G + D + +G G+ + +G+D L +M E+
Sbjct: 386 SKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQ---VVLGMDMGLREMCVGEKR 442
Query: 216 ILYLGPRYGFGEAGKPKFGIEPNAELIYEVTL 247
+ + P G+GEAG + +A L++++ L
Sbjct: 443 TVIIPPHLGYGEAGVDG-EVPGSAVLVFDIEL 473
Score = 59.7 bits (143), Expect = 5e-09
Identities = 31/87 (35%), Positives = 47/87 (54%)
Query: 50 GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKP 109
GD + HY L +G DS+ + + + LG GQV+ D+G+ M GE ++ P
Sbjct: 389 GDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPP 448
Query: 110 EYAYGSAGSLPKIPSNATLFFEIELLD 136
YG AG ++P +A L F+IELL+
Sbjct: 449 HLGYGEAGVDGEVPGSAVLVFDIELLE 475
>gi|52630440 FK506-binding protein 8 [Homo sapiens]
Length = 413
Score = 79.3 bits (194), Expect = 7e-15
Identities = 68/287 (23%), Positives = 121/287 (42%), Gaps = 8/287 (2%)
Query: 141 DLFEDGGIIRRTKRKGE-GYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHD 197
D+ +G + ++T G G S P +G V +HL+ G R+ + ++ FT+G D D
Sbjct: 95 DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLG---DCD 151
Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW 257
+ +D ++ M E ++ +Y +G G I P+A L EVTLK+ +
Sbjct: 152 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAVDGPDLE 211
Query: 258 EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL--EMEYGLSEKESKASESF 315
+ +E++ A +E G +++ ++ A Y + + + ++ +E
Sbjct: 212 MLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQL 271
Query: 316 LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 375
+ NLA LKL Y A+ C L N K L+R+G+ E+ A
Sbjct: 272 KVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILR 331
Query: 376 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAK 422
L++ P NK ++S KK + +Y M + AK
Sbjct: 332 AALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAK 378
Score = 51.2 bits (121), Expect = 2e-06
Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Query: 43 GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEI 102
G P+ G V VH + L NG + + VF+LG VI+A D+ V M GE
Sbjct: 113 GSSRPVKGQVVTVHLQTSLENGTRVQEEPE----LVFTLGDCDVIQALDLSVPLMDVGET 168
Query: 103 CHLLCKPEYAYGSAGS-LPKIPSNATLFFEIEL 134
+ +Y YG GS P IP +A L E+ L
Sbjct: 169 AMVTADSKYCYGPQGSRSPYIPPHAALCLEVTL 201
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 76.3 bits (186), Expect = 6e-14
Identities = 50/154 (32%), Positives = 85/154 (55%), Gaps = 17/154 (11%)
Query: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G
Sbjct: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308
Query: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+
Sbjct: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
Query: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKK 397
+ + AK DFE VL + P NK A ++S +KK
Sbjct: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKK 396
Score = 68.2 bits (165), Expect = 2e-11
Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%)
Query: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305
T +S + ES E ++A ++KEKG YFK GKY +A+ Y K +
Sbjct: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161
Query: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365
++ + N A Y +L+++ A C+ A+ L+ + K RRG A+ +
Sbjct: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215
Query: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423
+ E AK D+E+VLE+ P N A ++ + Q A + N + A++ K E + K+
Sbjct: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273
Query: 424 EANKAMGKKTSE 435
EA + + SE
Sbjct: 274 EAQQNKQQAISE 285
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 75.9 bits (185), Expect = 7e-14
Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%)
Query: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G
Sbjct: 101 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 149
Query: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+
Sbjct: 150 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 203
Query: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405
+ + AK DFE VL + P NK A ++S +K+ E D
Sbjct: 204 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 245
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 4/116 (3%)
Query: 322 NLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
N A Y +L+++ A C+ A+ L+ + K RRG A+ + + E AK D+E+VLE+
Sbjct: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
Query: 382 PQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE-EANKAMGKKTSE 435
P N A ++ + Q A + N + A++ K E + K+ EA + + SE
Sbjct: 73 PNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQIEAQQNKQQAISE 126
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 75.9 bits (185), Expect = 7e-14
Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%)
Query: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
++ +KS E ++ +++ ++ +QA K++G +FK GKY +A+ Y + G
Sbjct: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308
Query: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
++ + A LL A N AM YLK+++Y +A + C +A+ LD + K RRG A+
Sbjct: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
Query: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405
+ + AK DFE VL + P NK A ++S +K+ E D
Sbjct: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 404
Score = 68.2 bits (165), Expect = 2e-11
Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%)
Query: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305
T +S + ES E ++A ++KEKG YFK GKY +A+ Y K +
Sbjct: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161
Query: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365
++ + N A Y +L+++ A C+ A+ L+ + K RRG A+ +
Sbjct: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215
Query: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423
+ E AK D+E+VLE+ P N A ++ + Q A + N + A++ K E + K+
Sbjct: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273
Query: 424 EANKAMGKKTSE 435
EA + + SE
Sbjct: 274 EAQQNKQQAISE 285
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 75.1 bits (183), Expect = 1e-13
Identities = 44/147 (29%), Positives = 74/147 (50%), Gaps = 21/147 (14%)
Query: 248 KSFEKAKESWEMDTKEKL------EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEME 301
K K+K TK ++ E+A ++KE+G K G + +A+ +Y
Sbjct: 167 KEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYS--------- 217
Query: 302 YGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQ 361
ES + A + N A+CYL L++YT+AV+ C +AL LD N K YRR +A
Sbjct: 218 ------ESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAH 271
Query: 362 LLMNEFESAKGDFEKVLEVNPQNKAAR 388
+ +++S+ D +L++ P+N A+
Sbjct: 272 KALKDYKSSFADISNLLQIEPRNGPAQ 298
Score = 43.5 bits (101), Expect = 4e-04
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 7/111 (6%)
Query: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKL 330
++ G F+ G+Y +A YG+ + L+ + G S+ E ++ + N A C+LK
Sbjct: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQ-GSSDPEEES------VLYSNRAACHLKD 64
Query: 331 REYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
++ C AL L + K L RR A + ++ A D++ VL+++
Sbjct: 65 GNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
>gi|206725547 FK506 binding protein 7 isoform b precursor [Homo
sapiens]
Length = 221
Score = 72.0 bits (175), Expect = 1e-12
Identities = 45/104 (43%), Positives = 59/104 (56%), Gaps = 3/104 (2%)
Query: 34 LKIVKRVGNGEETPMIGDKVYVHYKGKLS-NGKKFDSSHDRNE--PFVFSLGKGQVIKAW 90
++++ R N +T GD + HY G L+ +G KF S +NE P F LG GQVIK
Sbjct: 37 IEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGL 96
Query: 91 DIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIEL 134
DI + M GE ++ P +AYG G KIP +ATL FEIEL
Sbjct: 97 DIAMTDMCPGEKRKVVIPPSFAYGKEGYEGKIPPDATLIFEIEL 140
Score = 32.7 bits (73), Expect = 0.70
Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 10/126 (7%)
Query: 151 RTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQ 210
+T +KG+ + +G + + C + F +G G+ + G+D A+ M
Sbjct: 48 KTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQ---VIKGLDIAMTDMC 104
Query: 211 REEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWE------MDTKEK 264
E+ + + P + +G+ G + I P+A LI+E+ L + K S E MD +
Sbjct: 105 PGEKRKVVIPPSFAYGKEGY-EGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQ 163
Query: 265 LEQAAI 270
L +A I
Sbjct: 164 LSKAEI 169
>gi|31317231 FK506 binding protein 7 isoform a precursor [Homo
sapiens]
Length = 222
Score = 68.6 bits (166), Expect = 1e-11
Identities = 45/105 (42%), Positives = 60/105 (57%), Gaps = 4/105 (3%)
Query: 34 LKIVKRVGNGEETPMIGDKVYVHYKGKLS-NGKKFDSSHDRNE--PFVFSLGKGQVIKAW 90
++++ R N +T GD + HY G L+ +G KF S +NE P F LG GQVIK
Sbjct: 37 IEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGL 96
Query: 91 DIGVATMKKGEICHLLCKPEYAYGSAG-SLPKIPSNATLFFEIEL 134
DI + M GE ++ P +AYG G + KIP +ATL FEIEL
Sbjct: 97 DIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIEL 141
Score = 37.0 bits (84), Expect = 0.037
Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 9/126 (7%)
Query: 151 RTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQ 210
+T +KG+ + +G + + C + F +G G+ + G+D A+ M
Sbjct: 48 KTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQ---VIKGLDIAMTDMC 104
Query: 211 REEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWE------MDTKEK 264
E+ + + P + +G+ G + I P+A LI+E+ L + K S E MD +
Sbjct: 105 PGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQ 164
Query: 265 LEQAAI 270
L +A I
Sbjct: 165 LSKAEI 170
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 67.4 bits (163), Expect = 3e-11
Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 16/195 (8%)
Query: 247 LKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSE 306
L E ++ + KEK A KEKG F G Y +AV+ Y + +S L
Sbjct: 188 LSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPT------ 241
Query: 307 KESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE 366
+ A+ N A +KL+ + A + C+K L L+ N K L RR N+
Sbjct: 242 ----------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNK 291
Query: 367 FESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
A D KVL+V P N A+ +S ++ K E + E+
Sbjct: 292 LREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEE 351
Query: 427 KAMGKKTSEGVTNEK 441
G+K +G ++K
Sbjct: 352 GKSGRKHEDGGGDKK 366
Score = 61.6 bits (148), Expect = 1e-09
Identities = 51/198 (25%), Positives = 91/198 (45%), Gaps = 28/198 (14%)
Query: 261 TKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAF 320
T EK +A +KE+G Y A+ +Y + + ++ KE A +
Sbjct: 618 TDEKTFKA--LKEEGNQCVNDKNYKDALSKYSECLK-------INNKEC--------AIY 660
Query: 321 LNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV 380
N A+CYLKL ++ +A + CD+AL L N K YRR A + ++ + D KV+ +
Sbjct: 661 TNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILL 720
Query: 381 NPQNKAARLQ-------ISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKT 433
+P A+++ +++ K A + E++RR + + KEE + G+ +
Sbjct: 721 DPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERR----KIEIQEVNEGKEEPGRPAGEVS 776
Query: 434 SEGVTNEKGTDSQAMEEE 451
+ +EKG S E+
Sbjct: 777 MGCLASEKGGKSSRSPED 794
Score = 49.7 bits (117), Expect = 6e-06
Identities = 49/197 (24%), Positives = 94/197 (47%), Gaps = 21/197 (10%)
Query: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAM 325
E A +K +G F+ G++ +A +Y ++ LE S+ ++ L + N A
Sbjct: 443 ENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLE------PAGSEIADD-LSILYSNRAA 495
Query: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV----- 380
CYLK + ++ C++AL L + K L RR A + ++ A D++ VL++
Sbjct: 496 CYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQ 555
Query: 381 ---NPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTS--- 434
+ N+ +R+ + + +E + A++ + A AKE +K G +S
Sbjct: 556 LANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQ-AWHPAKEMISKQAGDSSSHRQ 614
Query: 435 EGVTNEKGTDSQAMEEE 451
+G+T+EK +A++EE
Sbjct: 615 QGITDEK--TFKALKEE 629
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 67.4 bits (163), Expect = 3e-11
Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 16/195 (8%)
Query: 247 LKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSE 306
L E ++ + KEK A KEKG F G Y +AV+ Y + +S L
Sbjct: 188 LSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPT------ 241
Query: 307 KESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE 366
+ A+ N A +KL+ + A + C+K L L+ N K L RR N+
Sbjct: 242 ----------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNK 291
Query: 367 FESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
A D KVL+V P N A+ +S ++ K E + E+
Sbjct: 292 LREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEE 351
Query: 427 KAMGKKTSEGVTNEK 441
G+K +G ++K
Sbjct: 352 GKSGRKHEDGGGDKK 366
Score = 61.6 bits (148), Expect = 1e-09
Identities = 51/198 (25%), Positives = 91/198 (45%), Gaps = 28/198 (14%)
Query: 261 TKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAF 320
T EK +A +KE+G Y A+ +Y + + ++ KE A +
Sbjct: 618 TDEKTFKA--LKEEGNQCVNDKNYKDALSKYSECLK-------INNKEC--------AIY 660
Query: 321 LNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV 380
N A+CYLKL ++ +A + CD+AL L N K YRR A + ++ + D KV+ +
Sbjct: 661 TNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILL 720
Query: 381 NPQNKAARLQ-------ISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKT 433
+P A+++ +++ K A + E++RR + + KEE + G+ +
Sbjct: 721 DPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERR----KIEIQEVNEGKEEPGRPAGEVS 776
Query: 434 SEGVTNEKGTDSQAMEEE 451
+ +EKG S E+
Sbjct: 777 MGCLASEKGGKSSRSPED 794
Score = 49.7 bits (117), Expect = 6e-06
Identities = 49/197 (24%), Positives = 94/197 (47%), Gaps = 21/197 (10%)
Query: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAM 325
E A +K +G F+ G++ +A +Y ++ LE S+ ++ L + N A
Sbjct: 443 ENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLE------PAGSEIADD-LSILYSNRAA 495
Query: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV----- 380
CYLK + ++ C++AL L + K L RR A + ++ A D++ VL++
Sbjct: 496 CYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQ 555
Query: 381 ---NPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTS--- 434
+ N+ +R+ + + +E + A++ + A AKE +K G +S
Sbjct: 556 LANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQ-AWHPAKEMISKQAGDSSSHRQ 614
Query: 435 EGVTNEKGTDSQAMEEE 451
+G+T+EK +A++EE
Sbjct: 615 QGITDEK--TFKALKEE 629
>gi|74272280 aryl hydrocarbon receptor interacting protein-like 1
isoform 3 [Homo sapiens]
Length = 324
Score = 66.2 bits (160), Expect = 6e-11
Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 10/189 (5%)
Query: 254 KESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKAS- 312
+E+W + EK++ ++ +G FK G+Y +A +Y + + L L KE
Sbjct: 104 RETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLR---NLQTKEKPWEV 160
Query: 313 -----ESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEF 367
E + LN C LK EY + +E L K Y R A +
Sbjct: 161 QWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNE 220
Query: 368 ESAKGDFEKVLEVNP-QNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
AK D +KVLE+ P KA R ++ + + + E E +R NM + A Q E
Sbjct: 221 AEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPT 280
Query: 427 KAMGKKTSE 435
+ + ++E
Sbjct: 281 EPPAQSSTE 289
>gi|74272278 aryl hydrocarbon receptor interacting protein-like 1
isoform 2 [Homo sapiens]
Length = 321
Score = 66.2 bits (160), Expect = 6e-11
Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 10/189 (5%)
Query: 254 KESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKAS- 312
+E+W + EK++ ++ +G FK G+Y +A +Y + + L L KE
Sbjct: 101 RETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLR---NLQTKEKPWEV 157
Query: 313 -----ESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEF 367
E + LN C LK EY + +E L K Y R A +
Sbjct: 158 QWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNE 217
Query: 368 ESAKGDFEKVLEVNP-QNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
AK D +KVLE+ P KA R ++ + + + E E +R NM + A Q E
Sbjct: 218 AEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPT 277
Query: 427 KAMGKKTSE 435
+ + ++E
Sbjct: 278 EPPAQSSTE 286
>gi|74272276 aryl hydrocarbon receptor interacting protein-like 1
isoform 1 [Homo sapiens]
Length = 384
Score = 66.2 bits (160), Expect = 6e-11
Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 10/189 (5%)
Query: 254 KESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKAS- 312
+E+W + EK++ ++ +G FK G+Y +A +Y + + L L KE
Sbjct: 164 RETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLR---NLQTKEKPWEV 220
Query: 313 -----ESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEF 367
E + LN C LK EY + +E L K Y R A +
Sbjct: 221 QWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNE 280
Query: 368 ESAKGDFEKVLEVNP-QNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
AK D +KVLE+ P KA R ++ + + + E E +R NM + A Q E
Sbjct: 281 AEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPT 340
Query: 427 KAMGKKTSE 435
+ + ++E
Sbjct: 341 EPPAQSSTE 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,269,648
Number of Sequences: 37866
Number of extensions: 803362
Number of successful extensions: 2134
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1851
Number of HSP's gapped (non-prelim): 234
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.