Guide to the Human Genome
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Search of human proteins with 224809327

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
         (457 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]         924   0.0  
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]         924   0.0  
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]           924   0.0  
gi|4503729 FK506 binding protein 52 [Homo sapiens]                    519   e-147
gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]         458   e-129
gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo sa...   101   2e-21
gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]            100   3e-21
gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]             100   3e-21
gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo sapi...    99   6e-21
gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]    99   6e-21
gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]    99   6e-21
gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens]           90   4e-18
gi|192448443 FK506 binding protein 10 [Homo sapiens]                   85   1e-16
gi|4826932 peptidylprolyl isomerase D [Homo sapiens]                   83   5e-16
gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens]          83   5e-16
gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens]          82   8e-16
gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]               81   2e-15
gi|33469985 FK506 binding protein 9 [Homo sapiens]                     80   4e-15
gi|52630440 FK506-binding protein 8 [Homo sapiens]                     79   7e-15
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H...    76   6e-14
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H...    76   7e-14
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H...    76   7e-14
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo...    75   1e-13
gi|206725547 FK506 binding protein 7 isoform b precursor [Homo s...    72   1e-12
gi|31317231 FK506 binding protein 7 isoform a precursor [Homo sa...    69   1e-11
gi|27262638 sperm associated antigen 1 [Homo sapiens]                  67   3e-11
gi|27262636 sperm associated antigen 1 [Homo sapiens]                  67   3e-11
gi|74272280 aryl hydrocarbon receptor interacting protein-like 1...    66   6e-11
gi|74272278 aryl hydrocarbon receptor interacting protein-like 1...    66   6e-11
gi|74272276 aryl hydrocarbon receptor interacting protein-like 1...    66   6e-11

>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score =  924 bits (2388), Expect = 0.0
 Identities = 457/457 (100%), Positives = 457/457 (100%)

Query: 1   MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
           MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
Sbjct: 1   MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60

Query: 61  LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
           LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
Sbjct: 61  LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120

Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
           KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180

Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240
           FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240

Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300
           LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
Sbjct: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300

Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360
           EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
Sbjct: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360

Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420
           QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
Sbjct: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420

Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457
           AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
Sbjct: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457


>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score =  924 bits (2388), Expect = 0.0
 Identities = 457/457 (100%), Positives = 457/457 (100%)

Query: 1   MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
           MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
Sbjct: 1   MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60

Query: 61  LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
           LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
Sbjct: 61  LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120

Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
           KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180

Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240
           FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240

Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300
           LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
Sbjct: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300

Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360
           EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
Sbjct: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360

Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420
           QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
Sbjct: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420

Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457
           AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
Sbjct: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457


>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score =  924 bits (2388), Expect = 0.0
 Identities = 457/457 (100%), Positives = 457/457 (100%)

Query: 1   MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
           MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
Sbjct: 1   MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60

Query: 61  LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
           LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
Sbjct: 61  LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120

Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
           KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180

Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240
           FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE 240

Query: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300
           LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
Sbjct: 241 LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM 300

Query: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360
           EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
Sbjct: 301 EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA 360

Query: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420
           QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
Sbjct: 361 QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD 420

Query: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457
           AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
Sbjct: 421 AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 457


>gi|4503729 FK506 binding protein 52 [Homo sapiens]
          Length = 459

 Score =  519 bits (1336), Expect = e-147
 Identities = 252/454 (55%), Positives = 340/454 (74%), Gaps = 11/454 (2%)

Query: 1   MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
           MT +E       + +A +  +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G 
Sbjct: 1   MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 60

Query: 61  LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
           L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P
Sbjct: 61  LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 120

Query: 121 KIPSNATLFFEIELLDFKGEDLFE--DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 178
           KIP NATL FE+EL +FKGEDL E  DGGIIRR + +GEGY+ PNEGA VE+ LEG    
Sbjct: 121 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 180

Query: 179 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 238
           ++FD R++ F +GEGE+ D+P G+++A+++M++ E  I+YL P Y FG  GK KF I PN
Sbjct: 181 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 240

Query: 239 AELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL 298
           AEL YE+ LKSFEKAKESWEM+++EKLEQ+ IVKE+GTVYFK GKY QA++QY KIVSWL
Sbjct: 241 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 300

Query: 299 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 358
           E E   S +E++ +++  LA+ LNLAMC+LKL+ ++ A+E C+KAL LDS NEKGL+RRG
Sbjct: 301 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 360

Query: 359 EAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 418
           EA L +N+FE A+ DF+KVL++ P NKAA+ Q+++CQ++ +    R++++YANMF++ AE
Sbjct: 361 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 420

Query: 419 QDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEK 452
           ++ K +A  + G         +  TD++  EE+K
Sbjct: 421 EENKAKAEASSG---------DHPTDTEMKEEQK 445


>gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]
          Length = 268

 Score =  458 bits (1178), Expect = e-129
 Identities = 222/222 (100%), Positives = 222/222 (100%)

Query: 1   MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
           MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
Sbjct: 1   MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60

Query: 61  LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
           LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
Sbjct: 61  LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120

Query: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180
           KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM 180

Query: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPR 222
           FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPR
Sbjct: 181 FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPR 222



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 39/123 (31%), Positives = 61/123 (49%), Gaps = 14/123 (11%)

Query: 138 KGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCG-GRMFDC-----RDVAFT 189
           +GED+   +D G+++  KR G G   P  G  V +H +G+   G+ FD          F+
Sbjct: 21  QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 80

Query: 190 VGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGK-PKFGIEPNAELIYEVTLK 248
           +G+G+   +    D  +  M++ E C L   P Y +G AG  PK  I  NA L +E+ L 
Sbjct: 81  LGKGQ---VIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPK--IPSNATLFFEIELL 135

Query: 249 SFE 251
            F+
Sbjct: 136 DFK 138


>gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo
           sapiens]
          Length = 108

 Score =  101 bits (251), Expect = 2e-21
 Identities = 49/98 (50%), Positives = 62/98 (63%)

Query: 41  GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100
           G+G   P  G    VHY G L NGKKFDSS DRN+PF F +GK +VIK ++ G A M  G
Sbjct: 11  GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLG 70

Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFK 138
           +   L C P+ AYG+ G    IP NATL F++ELL+ +
Sbjct: 71  QRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 108



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 10/111 (9%)

Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200
           G+   T   G+G + P +G T  +H  G    G+ FD      +   F +G+ E   +  
Sbjct: 2   GVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQE---VIK 58

Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251
           G ++   +M   ++  L   P   +G  G P   I PNA LI++V L + E
Sbjct: 59  GFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGV-IPPNATLIFDVELLNLE 108


>gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]
          Length = 108

 Score =  100 bits (249), Expect = 3e-21
 Identities = 49/95 (51%), Positives = 61/95 (64%)

Query: 41  GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100
           G+G   P  G    VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ GVA M  G
Sbjct: 11  GDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVG 70

Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
           +   L   P+YAYG+ G    IP +ATL F++ELL
Sbjct: 71  QRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL 105



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 10/111 (9%)

Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200
           G+   T   G+G + P  G T  +H  G    G+ FD      +   F +G+ E   +  
Sbjct: 2   GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQE---VIR 58

Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251
           G ++ + +M   ++  L + P Y +G  G P   I P+A L+++V L   E
Sbjct: 59  GWEEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 108


>gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]
          Length = 108

 Score =  100 bits (249), Expect = 3e-21
 Identities = 49/95 (51%), Positives = 61/95 (64%)

Query: 41  GNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKG 100
           G+G   P  G    VHY G L +GKKFDSS DRN+PF F LGK +VI+ W+ GVA M  G
Sbjct: 11  GDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVG 70

Query: 101 EICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
           +   L   P+YAYG+ G    IP +ATL F++ELL
Sbjct: 71  QRAKLTISPDYAYGATGHPGIIPPHATLVFDVELL 105



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 10/111 (9%)

Query: 147 GIIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPI 200
           G+   T   G+G + P  G T  +H  G    G+ FD      +   F +G+ E   +  
Sbjct: 2   GVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQE---VIR 58

Query: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFE 251
           G ++ + +M   ++  L + P Y +G  G P   I P+A L+++V L   E
Sbjct: 59  GWEEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 108


>gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo
           sapiens]
          Length = 142

 Score = 99.4 bits (246), Expect = 6e-21
 Identities = 51/100 (51%), Positives = 65/100 (65%)

Query: 36  IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
           + KRV +       GD +++HY GKL +G +FDSS  +N+PFVFSLG GQVIK WD G+ 
Sbjct: 35  VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94

Query: 96  TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
            M +GE   L+   E  YG  G+ PKIP  ATL FE+ELL
Sbjct: 95  GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134


>gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
          Length = 142

 Score = 99.4 bits (246), Expect = 6e-21
 Identities = 51/100 (51%), Positives = 65/100 (65%)

Query: 36  IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
           + KRV +       GD +++HY GKL +G +FDSS  +N+PFVFSLG GQVIK WD G+ 
Sbjct: 35  VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94

Query: 96  TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
            M +GE   L+   E  YG  G+ PKIP  ATL FE+ELL
Sbjct: 95  GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134


>gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
          Length = 142

 Score = 99.4 bits (246), Expect = 6e-21
 Identities = 51/100 (51%), Positives = 65/100 (65%)

Query: 36  IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
           + KRV +       GD +++HY GKL +G +FDSS  +N+PFVFSLG GQVIK WD G+ 
Sbjct: 35  VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94

Query: 96  TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
            M +GE   L+   E  YG  G+ PKIP  ATL FE+ELL
Sbjct: 95  GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134


>gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens]
          Length = 349

 Score = 90.1 bits (222), Expect = 4e-18
 Identities = 74/249 (29%), Positives = 113/249 (45%), Gaps = 25/249 (10%)

Query: 145 DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIG--I 202
           DG  +++   +G G   P  G+   +   G   G          T+G G   +   G  I
Sbjct: 101 DGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELI 160

Query: 203 DKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTK 262
           +K LE M + E+  L L      G +G P             +TL SF + ++SWE++T 
Sbjct: 161 EKCLESMCQGEEAELQLP-----GHSGPP-----------VRLTLASFTQGRDSWELETS 204

Query: 263 EKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLN 322
           EK   A   + +GT  F+ G    A   YG+ +  L     L+       E  +L A  N
Sbjct: 205 EKEALAREERARGTELFRAGNPEGAARCYGRALRLL-----LTLPPPGPPERTVLHA--N 257

Query: 323 LAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382
           LA C L L +   A + CD+ L  +  + K LYRRG AQ  +   E A  D +KVL ++P
Sbjct: 258 LAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDP 317

Query: 383 QNKAARLQI 391
           +N+AA+ ++
Sbjct: 318 KNRAAQEEL 326


>gi|192448443 FK506 binding protein 10 [Homo sapiens]
          Length = 582

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 68/223 (30%), Positives = 100/223 (44%), Gaps = 17/223 (7%)

Query: 49  IGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCK 108
           +GD V  HY G   +GKKFDSS+DRN      +G G++I   D G+  M   E   L+  
Sbjct: 61  MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120

Query: 109 PEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATV 168
           P   YGS G    IP +ATL+F++ LLD   +   ED   +    R         +G  V
Sbjct: 121 PHLGYGSIGLAGLIPPDATLYFDVVLLDVWNK---EDTVQVSTLLRPPHCPRMVQDGDFV 177

Query: 169 EIHLEGR-CGGRMFDCRDVAFTVGEGEDHDIPI-------GIDKALEKMQREEQCILYLG 220
             H  G    G  FD      +  +G  +D  +       G+D+ L  M   E+  + + 
Sbjct: 178 RYHYNGTLLDGTSFDT-----SYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIP 232

Query: 221 PRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKE 263
           P   +GE G     I P A L++ V L      K++ +++T E
Sbjct: 233 PFLAYGEKGYGTV-IPPQASLVFHVLLIDVHNPKDAVQLETLE 274



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 74/267 (27%), Positives = 114/267 (42%), Gaps = 22/267 (8%)

Query: 24  DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
           D+ + KD   L+ ++           GD +  HY G L +G  FDSS+ RN  +   +G+
Sbjct: 260 DVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQ 319

Query: 84  GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG-EDL 142
           G +I   D G+     GE   +   P  AYG  G+  KIP +A L F + ++DF    D+
Sbjct: 320 GYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADV 379

Query: 143 FEDGGIIRRTKRKGEGYSNPNE-GATVEIHLEGRC--GGRMFDCRDVA----FTVGEGED 195
            E    IR   R  E  +   + G  V  H       G ++F   D       T+G  + 
Sbjct: 380 VE----IRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANK- 434

Query: 196 HDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255
             +  G+D  L+ M   E+  L + P    GE+G    G+  +A L++EV L S E    
Sbjct: 435 --VIEGLDTGLQGMCVGERRQLIVPPHLAHGESGAR--GVPGSAVLLFEVELVSREDGLP 490

Query: 256 S-----WEMDTKEKLEQAAIVKEKGTV 277
           +     W  D    L +   + + G V
Sbjct: 491 TGYLFVWHKDPPANLFEDMDLNKDGEV 517



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 67/249 (26%), Positives = 105/249 (42%), Gaps = 23/249 (9%)

Query: 24  DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
           D+ +K+D   +  + R  +       GD V  HY G L +G  FD+S+ +   +   +G 
Sbjct: 148 DVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGS 207

Query: 84  GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKG---- 139
           G +IK  D G+  M  GE   ++  P  AYG  G    IP  A+L F + L+D       
Sbjct: 208 GWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDA 267

Query: 140 ---EDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFD---CRDVAFTVGE 192
              E L    G +RR             G  +  H  G    G +FD    R+  +    
Sbjct: 268 VQLETLELPPGCVRRA----------GAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYI 317

Query: 193 GEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK 252
           G+ + IP G+D+ L+     E+  + + P   +GE G     I  +A LI+ V +  F  
Sbjct: 318 GQGYIIP-GMDQGLQGACMGERRRITIPPHLAYGENGTGD-KIPGSAVLIFNVHVIDFHN 375

Query: 253 AKESWEMDT 261
             +  E+ T
Sbjct: 376 PADVVEIRT 384


>gi|4826932 peptidylprolyl isomerase D [Homo sapiens]
          Length = 370

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 39/144 (27%), Positives = 79/144 (54%), Gaps = 1/144 (0%)

Query: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKAS-ESFLLAAFLNLAMCYLK 329
           +K  G  +FK   +  A+ +Y +++ +++    + E   +A  +   L+  LN+  C LK
Sbjct: 226 LKNIGNTFFKSQNWEMAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACKLK 285

Query: 330 LREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARL 389
           +  +  A++ C +AL LD +N K LYRR +    + E++ A  D +K   + P++KA + 
Sbjct: 286 MSNWQGAIDSCLEALELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQGIAPEDKAIQA 345

Query: 390 QISMCQKKAKEHNERDRRIYANMF 413
           ++   ++K K   ++++ +YA MF
Sbjct: 346 ELLKVKQKIKAQKDKEKAVYAKMF 369


>gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens]
          Length = 327

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 50/137 (36%), Positives = 76/137 (55%), Gaps = 4/137 (2%)

Query: 4   DEGAKNNEESPTATVAEQGED--ITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKL 61
           ++G    +++P  ++ E+     +    DRGVLK V R G G+        V V Y G L
Sbjct: 7   NQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDAS-VLVKYSGYL 65

Query: 62  SN-GKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
            +  + FDS++ R  P +  LG+   +   ++G+ +M++GE+   L KP YAYG+ G  P
Sbjct: 66  EHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPP 125

Query: 121 KIPSNATLFFEIELLDF 137
            IP N T+ FEIELLDF
Sbjct: 126 LIPPNTTVLFEIELLDF 142



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 71/291 (24%), Positives = 127/291 (43%), Gaps = 24/291 (8%)

Query: 141 DLFEDGGIIRRTKRKGEG-YSNPNEGATVEI-----HLEGRCGGRMFDCRDVAFTVGEGE 194
           D+  D G+++   R+G G    P+    V+      H++       F        +GE  
Sbjct: 31  DISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGE-- 88

Query: 195 DHDIPI-GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKA 253
             DI + G++  L  M+R E       P Y +G  G P   I PN  +++E+ L  F   
Sbjct: 89  --DITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIELLDFLDC 145

Query: 254 KESW-----------EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEY 302
            ES            +   ++ L+ AA  +E G   F+  ++  A ++Y + +  L    
Sbjct: 146 AESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRS 205

Query: 303 GLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQL 362
              E E    E+  L   LNL+  YLKL   T A+   ++AL +D  N K L+R G+A L
Sbjct: 206 APPE-EQHLVEAAKLPVLLNLSFTYLKLDRPTIALCYGEQALIIDQKNAKALFRCGQACL 264

Query: 363 LMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMF 413
           L+ E++ A+    +  +  P N     ++       +++ ++++ ++  MF
Sbjct: 265 LLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMF 315


>gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens]
          Length = 322

 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 47/109 (43%), Positives = 64/109 (58%), Gaps = 2/109 (1%)

Query: 30  DRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSN-GKKFDSSHDRNEPFVFSLGKGQVIK 88
           DRGVLK V R G G+        V V Y G L +  + FDS++ R  P +  LG+   + 
Sbjct: 30  DRGVLKDVIREGAGDLVAPDAS-VLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLW 88

Query: 89  AWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF 137
             ++G+ +M++GE+   L KP YAYG+ G  P IP N T+ FEIELLDF
Sbjct: 89  GMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDF 137



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 71/291 (24%), Positives = 127/291 (43%), Gaps = 24/291 (8%)

Query: 141 DLFEDGGIIRRTKRKGEG-YSNPNEGATVEI-----HLEGRCGGRMFDCRDVAFTVGEGE 194
           D+  D G+++   R+G G    P+    V+      H++       F        +GE  
Sbjct: 26  DISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGE-- 83

Query: 195 DHDIPI-GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKA 253
             DI + G++  L  M+R E       P Y +G  G P   I PN  +++E+ L  F   
Sbjct: 84  --DITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIELLDFLDC 140

Query: 254 KESW-----------EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEY 302
            ES            +   ++ L+ AA  +E G   F+  ++  A ++Y + +  L    
Sbjct: 141 AESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRS 200

Query: 303 GLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQL 362
              E E    E+  L   LNL+  YLKL   T A+   ++AL +D  N K L+R G+A L
Sbjct: 201 APPE-EQHLVEAAKLPVLLNLSFTYLKLDRPTIALCYGEQALIIDQKNAKALFRCGQACL 259

Query: 363 LMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMF 413
           L+ E++ A+    +  +  P N     ++       +++ ++++ ++  MF
Sbjct: 260 LLTEYQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMF 310


>gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]
          Length = 224

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 52/140 (37%), Positives = 72/140 (51%), Gaps = 11/140 (7%)

Query: 5   EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG 64
           +  K NE+ P  T +E+  D    K     K V + G+    P  GD V+  Y G L +G
Sbjct: 86  KNVKLNEDKPKETKSEETLDEGPPK---YTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDG 142

Query: 65  KKFDSSHDRN-------EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG 117
             FD++   +       +P  F +G G+VI+ WD  + TM KGE   L  +PE+AYG  G
Sbjct: 143 TVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKG 202

Query: 118 SL-PKIPSNATLFFEIELLD 136
               KIP NA L FE+EL+D
Sbjct: 203 QPDAKIPPNAKLTFEVELVD 222



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 18/125 (14%)

Query: 138 KGEDLFEDGG--IIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFD------------ 182
           K E+  ++G     +   +KG+  + P +G  V     G    G +FD            
Sbjct: 99  KSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKN 158

Query: 183 CRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELI 242
            + ++F VG G+   +  G D+AL  M + E+  L + P + +G+ G+P   I PNA+L 
Sbjct: 159 AKPLSFKVGVGK---VIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLT 215

Query: 243 YEVTL 247
           +EV L
Sbjct: 216 FEVEL 220


>gi|33469985 FK506 binding protein 9 [Homo sapiens]
          Length = 570

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 70/230 (30%), Positives = 100/230 (43%), Gaps = 9/230 (3%)

Query: 50  GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKP 109
           GD V  HY G   +G+KFDSS+DR+  F   +GKGQ+I   D  +  M   E   +   P
Sbjct: 54  GDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPP 113

Query: 110 EYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVE 169
           + AYG+ G    IP N+ L F++ L+D       ED   I    +             V 
Sbjct: 114 KLAYGNEGVSGVIPPNSVLHFDVLLMDIWNS---EDQVQIHTYFKPPSCPRTIQVSDFVR 170

Query: 170 IHLEGR-CGGRMFDC---RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGF 225
            H  G    G +FD    R   +    G    IP G+DK L  M   E+ I+ + P   +
Sbjct: 171 YHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIP-GMDKGLLGMCVGEKRIITIPPFLAY 229

Query: 226 GEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKG 275
           GE G  K  I   A L+++V L      K+S  ++ K   E    + + G
Sbjct: 230 GEDGDGK-DIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSG 278



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 68/259 (26%), Positives = 116/259 (44%), Gaps = 16/259 (6%)

Query: 24  DITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGK 83
           DI + +D+  +    +  +   T  + D V  HY G   +G  FDSSH+R + +   +G 
Sbjct: 140 DIWNSEDQVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGI 199

Query: 84  GQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDF---KGE 140
           G +I   D G+  M  GE   +   P  AYG  G    IP  A+L F++ LLD    K  
Sbjct: 200 GWLIPGMDKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDS 259

Query: 141 DLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGR-CGGRMFD---CRDVAFTVGEGEDH 196
              E+  +    +R  +       G  +  H  G    G +FD    R+  F    G+ +
Sbjct: 260 ISIENKVVPENCERISQ------SGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGY 313

Query: 197 DIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKES 256
            IP G+D+ L  +   E+  + + P  G+GE G+    I  +A L++++ +  F    +S
Sbjct: 314 VIP-GMDEGLLGVCIGEKRRIVVPPHLGYGEEGRG--NIPGSAVLVFDIHVIDFHNPSDS 370

Query: 257 WEMDTKEKLEQAAIVKEKG 275
             + +  K    +++ +KG
Sbjct: 371 ISITSHYKPPDCSVLSKKG 389



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 58/212 (27%), Positives = 94/212 (44%), Gaps = 14/212 (6%)

Query: 42  NGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGE 101
           N E     GD +  HY G L +G  FDSS+ RN  F   +G+G VI   D G+  +  GE
Sbjct: 270 NCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGE 329

Query: 102 ICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSN 161
              ++  P   YG  G    IP +A L F+I ++DF       D   I    +  +    
Sbjct: 330 KRRIVVPPHLGYGEEGR-GNIPGSAVLVFDIHVIDFHNPS---DSISITSHYKPPDCSVL 385

Query: 162 PNEGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKALEKMQREEQC 215
             +G  ++ H       G + D      +     +G G+   + +G+D  L +M   E+ 
Sbjct: 386 SKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQ---VVLGMDMGLREMCVGEKR 442

Query: 216 ILYLGPRYGFGEAGKPKFGIEPNAELIYEVTL 247
            + + P  G+GEAG     +  +A L++++ L
Sbjct: 443 TVIIPPHLGYGEAGVDG-EVPGSAVLVFDIEL 473



 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 31/87 (35%), Positives = 47/87 (54%)

Query: 50  GDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKP 109
           GD +  HY   L +G   DS+ +  + +   LG GQV+   D+G+  M  GE   ++  P
Sbjct: 389 GDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPP 448

Query: 110 EYAYGSAGSLPKIPSNATLFFEIELLD 136
              YG AG   ++P +A L F+IELL+
Sbjct: 449 HLGYGEAGVDGEVPGSAVLVFDIELLE 475


>gi|52630440 FK506-binding protein 8 [Homo sapiens]
          Length = 413

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 68/287 (23%), Positives = 121/287 (42%), Gaps = 8/287 (2%)

Query: 141 DLFEDGGIIRRTKRKGE-GYSNPNEGATVEIHLEGRC--GGRMFDCRDVAFTVGEGEDHD 197
           D+  +G + ++T   G  G S P +G  V +HL+     G R+ +  ++ FT+G   D D
Sbjct: 95  DILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLG---DCD 151

Query: 198 IPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESW 257
           +   +D ++  M   E  ++    +Y +G  G     I P+A L  EVTLK+     +  
Sbjct: 152 VIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAVDGPDLE 211

Query: 258 EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL--EMEYGLSEKESKASESF 315
            +  +E++  A   +E G  +++   ++ A   Y   +  +    +  ++ +E       
Sbjct: 212 MLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQL 271

Query: 316 LLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 375
            +    NLA   LKL  Y  A+  C   L     N K L+R+G+      E+  A     
Sbjct: 272 KVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILR 331

Query: 376 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAK 422
             L++ P NK    ++S   KK       +  +Y  M    +   AK
Sbjct: 332 AALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAK 378



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 5/93 (5%)

Query: 43  GEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEI 102
           G   P+ G  V VH +  L NG +     +     VF+LG   VI+A D+ V  M  GE 
Sbjct: 113 GSSRPVKGQVVTVHLQTSLENGTRVQEEPE----LVFTLGDCDVIQALDLSVPLMDVGET 168

Query: 103 CHLLCKPEYAYGSAGS-LPKIPSNATLFFEIEL 134
             +    +Y YG  GS  P IP +A L  E+ L
Sbjct: 169 AMVTADSKYCYGPQGSRSPYIPPHAALCLEVTL 201


>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
           sapiens]
          Length = 631

 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 50/154 (32%), Positives = 85/154 (55%), Gaps = 17/154 (11%)

Query: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
           ++ +KS E  ++  +++ ++  +QA   K++G  +FK GKY +A+  Y +         G
Sbjct: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308

Query: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
           ++   + A    LL A  N AM YLK+++Y +A + C +A+ LD +  K   RRG A+  
Sbjct: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362

Query: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKK 397
           + +   AK DFE VL + P NK A  ++S  +KK
Sbjct: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKK 396



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%)

Query: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305
           T +S  +  ES E       ++A ++KEKG  YFK GKY +A+  Y K +          
Sbjct: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161

Query: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365
                 ++ +      N A  Y +L+++  A   C+ A+ L+ +  K   RRG A+  + 
Sbjct: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215

Query: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423
           + E AK D+E+VLE+ P N  A  ++  + Q  A + N   +   A++  K  E + K+ 
Sbjct: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273

Query: 424 EANKAMGKKTSE 435
           EA +   +  SE
Sbjct: 274 EAQQNKQQAISE 285


>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
           sapiens]
          Length = 506

 Score = 75.9 bits (185), Expect = 7e-14
 Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%)

Query: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
           ++ +KS E  ++  +++ ++  +QA   K++G  +FK GKY +A+  Y +         G
Sbjct: 101 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 149

Query: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
           ++   + A    LL A  N AM YLK+++Y +A + C +A+ LD +  K   RRG A+  
Sbjct: 150 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 203

Query: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405
           + +   AK DFE VL + P NK A  ++S  +K+  E    D
Sbjct: 204 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 245



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 35/116 (30%), Positives = 60/116 (51%), Gaps = 4/116 (3%)

Query: 322 NLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
           N A  Y +L+++  A   C+ A+ L+ +  K   RRG A+  + + E AK D+E+VLE+ 
Sbjct: 13  NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72

Query: 382 PQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE-EANKAMGKKTSE 435
           P N  A  ++  + Q  A + N   +   A++  K  E + K+ EA +   +  SE
Sbjct: 73  PNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQIEAQQNKQQAISE 126


>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 75.9 bits (185), Expect = 7e-14
 Identities = 51/162 (31%), Positives = 87/162 (53%), Gaps = 17/162 (10%)

Query: 244 EVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYG 303
           ++ +KS E  ++  +++ ++  +QA   K++G  +FK GKY +A+  Y +         G
Sbjct: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTR---------G 308

Query: 304 LSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLL 363
           ++   + A    LL A  N AM YLK+++Y +A + C +A+ LD +  K   RRG A+  
Sbjct: 309 IAADGANA----LLPA--NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362

Query: 364 MNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 405
           + +   AK DFE VL + P NK A  ++S  +K+  E    D
Sbjct: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIEKGHWD 404



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 19/192 (9%)

Query: 246 TLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLS 305
           T +S  +  ES E       ++A ++KEKG  YFK GKY +A+  Y K +          
Sbjct: 111 THESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMD--------- 161

Query: 306 EKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMN 365
                 ++ +      N A  Y +L+++  A   C+ A+ L+ +  K   RRG A+  + 
Sbjct: 162 ------ADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQ 215

Query: 366 EFESAKGDFEKVLEVNPQNKAARLQI-SMCQKKAKEHNERDRRIYANMFKKFAEQDAKE- 423
           + E AK D+E+VLE+ P N  A  ++  + Q  A + N   +   A++  K  E + K+ 
Sbjct: 216 KLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKE--ADIVIKSTEGERKQI 273

Query: 424 EANKAMGKKTSE 435
           EA +   +  SE
Sbjct: 274 EAQQNKQQAISE 285


>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
           sapiens]
          Length = 309

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 44/147 (29%), Positives = 74/147 (50%), Gaps = 21/147 (14%)

Query: 248 KSFEKAKESWEMDTKEKL------EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEME 301
           K   K+K      TK ++      E+A ++KE+G    K G + +A+ +Y          
Sbjct: 167 KEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYS--------- 217

Query: 302 YGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQ 361
                 ES    +   A + N A+CYL L++YT+AV+ C +AL LD  N K  YRR +A 
Sbjct: 218 ------ESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAH 271

Query: 362 LLMNEFESAKGDFEKVLEVNPQNKAAR 388
             + +++S+  D   +L++ P+N  A+
Sbjct: 272 KALKDYKSSFADISNLLQIEPRNGPAQ 298



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 7/111 (6%)

Query: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKL 330
           ++  G   F+ G+Y +A   YG+ +  L+ + G S+ E ++        + N A C+LK 
Sbjct: 12  LRAAGNESFRNGQYAEASALYGRALRVLQAQ-GSSDPEEES------VLYSNRAACHLKD 64

Query: 331 REYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
                 ++ C  AL L   + K L RR  A   + ++  A  D++ VL+++
Sbjct: 65  GNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115


>gi|206725547 FK506 binding protein 7 isoform b precursor [Homo
           sapiens]
          Length = 221

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 45/104 (43%), Positives = 59/104 (56%), Gaps = 3/104 (2%)

Query: 34  LKIVKRVGNGEETPMIGDKVYVHYKGKLS-NGKKFDSSHDRNE--PFVFSLGKGQVIKAW 90
           ++++ R  N  +T   GD +  HY G L+ +G KF  S  +NE  P  F LG GQVIK  
Sbjct: 37  IEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGL 96

Query: 91  DIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIEL 134
           DI +  M  GE   ++  P +AYG  G   KIP +ATL FEIEL
Sbjct: 97  DIAMTDMCPGEKRKVVIPPSFAYGKEGYEGKIPPDATLIFEIEL 140



 Score = 32.7 bits (73), Expect = 0.70
 Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 10/126 (7%)

Query: 151 RTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQ 210
           +T +KG+  +   +G   +   +  C     +     F +G G+   +  G+D A+  M 
Sbjct: 48  KTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQ---VIKGLDIAMTDMC 104

Query: 211 REEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWE------MDTKEK 264
             E+  + + P + +G+ G  +  I P+A LI+E+ L +  K   S E      MD   +
Sbjct: 105 PGEKRKVVIPPSFAYGKEGY-EGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQ 163

Query: 265 LEQAAI 270
           L +A I
Sbjct: 164 LSKAEI 169


>gi|31317231 FK506 binding protein 7 isoform a precursor [Homo
           sapiens]
          Length = 222

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 45/105 (42%), Positives = 60/105 (57%), Gaps = 4/105 (3%)

Query: 34  LKIVKRVGNGEETPMIGDKVYVHYKGKLS-NGKKFDSSHDRNE--PFVFSLGKGQVIKAW 90
           ++++ R  N  +T   GD +  HY G L+ +G KF  S  +NE  P  F LG GQVIK  
Sbjct: 37  IEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGL 96

Query: 91  DIGVATMKKGEICHLLCKPEYAYGSAG-SLPKIPSNATLFFEIEL 134
           DI +  M  GE   ++  P +AYG  G +  KIP +ATL FEIEL
Sbjct: 97  DIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIEL 141



 Score = 37.0 bits (84), Expect = 0.037
 Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 9/126 (7%)

Query: 151 RTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQ 210
           +T +KG+  +   +G   +   +  C     +     F +G G+   +  G+D A+  M 
Sbjct: 48  KTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQ---VIKGLDIAMTDMC 104

Query: 211 REEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWE------MDTKEK 264
             E+  + + P + +G+ G  +  I P+A LI+E+ L +  K   S E      MD   +
Sbjct: 105 PGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQ 164

Query: 265 LEQAAI 270
           L +A I
Sbjct: 165 LSKAEI 170


>gi|27262638 sperm associated antigen 1 [Homo sapiens]
          Length = 926

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 16/195 (8%)

Query: 247 LKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSE 306
           L   E   ++  +  KEK   A   KEKG   F  G Y +AV+ Y + +S L        
Sbjct: 188 LSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPT------ 241

Query: 307 KESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE 366
                     + A+ N A   +KL+ +  A + C+K L L+  N K L RR       N+
Sbjct: 242 ----------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNK 291

Query: 367 FESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
              A  D  KVL+V P N  A+  +S  ++  K                  E +  E+  
Sbjct: 292 LREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEE 351

Query: 427 KAMGKKTSEGVTNEK 441
              G+K  +G  ++K
Sbjct: 352 GKSGRKHEDGGGDKK 366



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 51/198 (25%), Positives = 91/198 (45%), Gaps = 28/198 (14%)

Query: 261 TKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAF 320
           T EK  +A  +KE+G        Y  A+ +Y + +        ++ KE         A +
Sbjct: 618 TDEKTFKA--LKEEGNQCVNDKNYKDALSKYSECLK-------INNKEC--------AIY 660

Query: 321 LNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV 380
            N A+CYLKL ++ +A + CD+AL L   N K  YRR  A   +  ++ +  D  KV+ +
Sbjct: 661 TNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILL 720

Query: 381 NPQNKAARLQ-------ISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKT 433
           +P    A+++       +++  K A  + E++RR      +     + KEE  +  G+ +
Sbjct: 721 DPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERR----KIEIQEVNEGKEEPGRPAGEVS 776

Query: 434 SEGVTNEKGTDSQAMEEE 451
              + +EKG  S    E+
Sbjct: 777 MGCLASEKGGKSSRSPED 794



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 49/197 (24%), Positives = 94/197 (47%), Gaps = 21/197 (10%)

Query: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAM 325
           E  A +K +G   F+ G++ +A  +Y   ++ LE         S+ ++  L   + N A 
Sbjct: 443 ENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLE------PAGSEIADD-LSILYSNRAA 495

Query: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV----- 380
           CYLK    +  ++ C++AL L   + K L RR  A   + ++  A  D++ VL++     
Sbjct: 496 CYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQ 555

Query: 381 ---NPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTS--- 434
              +  N+ +R+ + +     +E       + A++  + A   AKE  +K  G  +S   
Sbjct: 556 LANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQ-AWHPAKEMISKQAGDSSSHRQ 614

Query: 435 EGVTNEKGTDSQAMEEE 451
           +G+T+EK    +A++EE
Sbjct: 615 QGITDEK--TFKALKEE 629


>gi|27262636 sperm associated antigen 1 [Homo sapiens]
          Length = 926

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 51/195 (26%), Positives = 78/195 (40%), Gaps = 16/195 (8%)

Query: 247 LKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSE 306
           L   E   ++  +  KEK   A   KEKG   F  G Y +AV+ Y + +S L        
Sbjct: 188 LSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPT------ 241

Query: 307 KESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE 366
                     + A+ N A   +KL+ +  A + C+K L L+  N K L RR       N+
Sbjct: 242 ----------VVAYNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNK 291

Query: 367 FESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
              A  D  KVL+V P N  A+  +S  ++  K                  E +  E+  
Sbjct: 292 LREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEE 351

Query: 427 KAMGKKTSEGVTNEK 441
              G+K  +G  ++K
Sbjct: 352 GKSGRKHEDGGGDKK 366



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 51/198 (25%), Positives = 91/198 (45%), Gaps = 28/198 (14%)

Query: 261 TKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAF 320
           T EK  +A  +KE+G        Y  A+ +Y + +        ++ KE         A +
Sbjct: 618 TDEKTFKA--LKEEGNQCVNDKNYKDALSKYSECLK-------INNKEC--------AIY 660

Query: 321 LNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV 380
            N A+CYLKL ++ +A + CD+AL L   N K  YRR  A   +  ++ +  D  KV+ +
Sbjct: 661 TNRALCYLKLCQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILL 720

Query: 381 NPQNKAARLQ-------ISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKT 433
           +P    A+++       +++  K A  + E++RR      +     + KEE  +  G+ +
Sbjct: 721 DPSIIEAKMELEEVTRLLNLKDKTAPFNKEKERR----KIEIQEVNEGKEEPGRPAGEVS 776

Query: 434 SEGVTNEKGTDSQAMEEE 451
              + +EKG  S    E+
Sbjct: 777 MGCLASEKGGKSSRSPED 794



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 49/197 (24%), Positives = 94/197 (47%), Gaps = 21/197 (10%)

Query: 266 EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAM 325
           E  A +K +G   F+ G++ +A  +Y   ++ LE         S+ ++  L   + N A 
Sbjct: 443 ENPAGLKSQGNELFRSGQFAEAAGKYSAAIALLE------PAGSEIADD-LSILYSNRAA 495

Query: 326 CYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEV----- 380
           CYLK    +  ++ C++AL L   + K L RR  A   + ++  A  D++ VL++     
Sbjct: 496 CYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQ 555

Query: 381 ---NPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTS--- 434
              +  N+ +R+ + +     +E       + A++  + A   AKE  +K  G  +S   
Sbjct: 556 LANDSVNRLSRILMELDGPNWREKLSPIPAVPASVPLQ-AWHPAKEMISKQAGDSSSHRQ 614

Query: 435 EGVTNEKGTDSQAMEEE 451
           +G+T+EK    +A++EE
Sbjct: 615 QGITDEK--TFKALKEE 629


>gi|74272280 aryl hydrocarbon receptor interacting protein-like 1
           isoform 3 [Homo sapiens]
          Length = 324

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 10/189 (5%)

Query: 254 KESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKAS- 312
           +E+W +   EK++   ++  +G   FK G+Y +A  +Y + +  L     L  KE     
Sbjct: 104 RETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLR---NLQTKEKPWEV 160

Query: 313 -----ESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEF 367
                E  +    LN   C LK  EY + +E     L       K  Y R  A   +   
Sbjct: 161 QWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNE 220

Query: 368 ESAKGDFEKVLEVNP-QNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
             AK D +KVLE+ P   KA R ++ + + +  E  E +R    NM  + A Q   E   
Sbjct: 221 AEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPT 280

Query: 427 KAMGKKTSE 435
           +   + ++E
Sbjct: 281 EPPAQSSTE 289


>gi|74272278 aryl hydrocarbon receptor interacting protein-like 1
           isoform 2 [Homo sapiens]
          Length = 321

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 10/189 (5%)

Query: 254 KESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKAS- 312
           +E+W +   EK++   ++  +G   FK G+Y +A  +Y + +  L     L  KE     
Sbjct: 101 RETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLR---NLQTKEKPWEV 157

Query: 313 -----ESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEF 367
                E  +    LN   C LK  EY + +E     L       K  Y R  A   +   
Sbjct: 158 QWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNE 217

Query: 368 ESAKGDFEKVLEVNP-QNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
             AK D +KVLE+ P   KA R ++ + + +  E  E +R    NM  + A Q   E   
Sbjct: 218 AEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPT 277

Query: 427 KAMGKKTSE 435
           +   + ++E
Sbjct: 278 EPPAQSSTE 286


>gi|74272276 aryl hydrocarbon receptor interacting protein-like 1
           isoform 1 [Homo sapiens]
          Length = 384

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 10/189 (5%)

Query: 254 KESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKAS- 312
           +E+W +   EK++   ++  +G   FK G+Y +A  +Y + +  L     L  KE     
Sbjct: 164 RETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLR---NLQTKEKPWEV 220

Query: 313 -----ESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEF 367
                E  +    LN   C LK  EY + +E     L       K  Y R  A   +   
Sbjct: 221 QWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNE 280

Query: 368 ESAKGDFEKVLEVNP-QNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEAN 426
             AK D +KVLE+ P   KA R ++ + + +  E  E +R    NM  + A Q   E   
Sbjct: 281 AEAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPT 340

Query: 427 KAMGKKTSE 435
           +   + ++E
Sbjct: 341 EPPAQSSTE 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.133    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,269,648
Number of Sequences: 37866
Number of extensions: 803362
Number of successful extensions: 2134
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1851
Number of HSP's gapped (non-prelim): 234
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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