Search of human proteins with 224591419

Search of human proteins with 224591419

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224591419 zinc finger and BTB domain containing 8B [Homo
sapiens]
         (495 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224591419 zinc finger and BTB domain containing 8B [Homo sapi...  1004   0.0  
gi|94721342 zinc finger and BTB domain containing 8A [Homo sapiens]   247   2e-65
gi|47679080 zinc finger and BTB domain containing 46 [Homo sapiens]   214   1e-55
gi|157694497 zinc finger and BTB domain containing 10 isoform b ...   125   1e-28
gi|157694499 zinc finger and BTB domain containing 10 isoform a ...   125   1e-28
gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]          123   3e-28
gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]    123   3e-28
gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]          123   3e-28
gi|167234429 zinc finger and BTB domain containing 17 [Homo sapi...   120   2e-27
gi|8923885 myoneurin [Homo sapiens]                                   112   6e-25
gi|14670366 POZ (BTB) and AT hook containing zinc finger 1 long ...   101   1e-21
gi|14670362 POZ (BTB) and AT hook containing zinc finger 1 long ...   101   1e-21
gi|14670360 POZ (BTB) and AT hook containing zinc finger 1 long ...   101   1e-21
gi|109134351 zinc finger and BTB domain containing 44 [Homo sapi...   100   2e-21
gi|209413766 zinc finger and BTB domain containing 43 [Homo sapi...    97   4e-20
gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens]     97   4e-20
gi|212286156 zinc finger and BTB domain containing 42 [Homo sapi...    93   6e-19
gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]     88   2e-17
gi|139394599 hypermethylated in cancer 2 [Homo sapiens]                87   5e-17
gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]      84   2e-16
gi|223972645 zinc finger protein 509 [Homo sapiens]                    84   3e-16
gi|239753123 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]      79   7e-15
gi|239747686 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]      79   7e-15
gi|239741555 PREDICTED: kelch repeat and BTB (POZ) domain contai...    79   7e-15
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]      79   7e-15
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]       79   7e-15
gi|11968150 GDNF-inducible zinc finger protein 1 [Homo sapiens]        78   2e-14
gi|5174473 intracisternal A particle-promoted polypeptide isofor...    75   1e-13
gi|223890235 intracisternal A particle-promoted polypeptide isof...    75   1e-13
gi|58000461 zinc finger protein 648 [Homo sapiens]                     75   2e-13

>gi|224591419 zinc finger and BTB domain containing 8B [Homo
           sapiens]
          Length = 495

 Score = 1004 bits (2596), Expect = 0.0
 Identities = 495/495 (100%), Positives = 495/495 (100%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS
Sbjct: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS 120
           GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS
Sbjct: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS 120

Query: 121 SLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSPA 180
           SLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSPA
Sbjct: 121 SLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSPA 180

Query: 181 EGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVEV 240
           EGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVEV
Sbjct: 181 EGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVEV 240

Query: 241 DVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHF 300
           DVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHF
Sbjct: 241 DVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHF 300

Query: 301 SRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHI 360
           SRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHI
Sbjct: 301 SRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHI 360

Query: 361 RSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRRFGL 420
           RSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRRFGL
Sbjct: 361 RSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRRFGL 420

Query: 421 CDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTDNDWPIYVESGEENDPAGDDSDD 480
           CDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTDNDWPIYVESGEENDPAGDDSDD
Sbjct: 421 CDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTDNDWPIYVESGEENDPAGDDSDD 480

Query: 481 KPQIQPNLSDRETLT 495
           KPQIQPNLSDRETLT
Sbjct: 481 KPQIQPNLSDRETLT 495


>gi|94721342 zinc finger and BTB domain containing 8A [Homo sapiens]
          Length = 441

 Score =  247 bits (630), Expect = 2e-65
 Identities = 178/510 (34%), Positives = 269/510 (52%), Gaps = 92/510 (18%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ME+ S+ + LL +LNEQR++D FCDCSI+VEG++FKAHRN+LFA+SGYF+ LL    +++
Sbjct: 1   MEISSHQSHLLQQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKET 60

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS 120
            + +TA+    + D F++ILDF+YSGKL L G+NVIEVMSAAS+LQM DV++ CKT+I+S
Sbjct: 61  SQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIEVMSAASFLQMTDVISVCKTFIKS 120

Query: 121 SLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSG--REGTSCGTKSLVSS 178
           SLDI  K EK+             + +   A ++ V+  S  SG  +EG+S     L  S
Sbjct: 121 SLDISEK-EKDRYF----------SLSDKDANSNGVERSSFYSGGWQEGSSSPRSHL--S 167

Query: 179 PAEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEV 238
           P +G   +         +  + HP            ++  N   P  + EP+ E     +
Sbjct: 168 PEQGTGII----SGKSWNKYNYHP------------ASQKNTQQPLAKHEPRKE----SI 207

Query: 239 EVDVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADH 298
           +     +L Q   P  + H +    S + V  + S+ HV Q        S   ++ DA+ 
Sbjct: 208 KKTKHLRLSQ---PSEVTHYKS---SKREVRTSDSSSHVSQ--------SEEQAQIDAE- 252

Query: 299 HFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKR 358
                ++  P G      S  DV +  + +D      +P    KCP+C +  K+K  LKR
Sbjct: 253 -----MDSTPVGYQYGQGS--DVTSKSFPDD------LPRMRFKCPYCTHVVKRKADLKR 299

Query: 359 HIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSHLSQ----G 414
           H+R HTGERPYPC+ CGKRF+R +HL SH  ++H++ + +IC+ C+R  T    Q    G
Sbjct: 300 HLRCHTGERPYPCQACGKRFSRLDHLSSHFRTIHQACK-LICRKCKRHVTDLTGQVVQEG 358

Query: 415 LRRFGLCDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTDNDWPI-------YVES 467
            RR+ LC+ C       +   D +PI+L   E    S    D D+ W +       YVE 
Sbjct: 359 TRRYRLCNECLA-----EFGIDSLPIDLE-AEQHLMSPSDGDKDSRWHLSEDENRSYVEI 412

Query: 468 GEENDPAGD---------DSDDKPQIQPNL 488
            E  D +GD         + +++ +I+PN+
Sbjct: 413 VE--DGSGDLVIQQVDDSEEEEEKEIKPNI 440


>gi|47679080 zinc finger and BTB domain containing 46 [Homo sapiens]
          Length = 589

 Score =  214 bits (545), Expect = 1e-55
 Identities = 164/521 (31%), Positives = 237/521 (45%), Gaps = 121/521 (23%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ME+ S+Y  LL ELNEQR+    CD  ++VEG++FKAH+N+L  +S YF+ L     + S
Sbjct: 8   MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS 120
            + +   LDIVT+  F  I+DF+YS  L L   NVIEVMSAAS+LQM D+V  C  +I++
Sbjct: 68  EQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKA 127

Query: 121 SLDICRKMEK-----------------EAAVAAAVA------------AAAAAAAAAAAA 151
           +LDI  K +                  EA ++A +A            + A ++  +A A
Sbjct: 128 ALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPADSSGDSAIA 187

Query: 152 AAHQVDSESPSSGREGTSCGTKSLVSSP------AEGEKSVECLRESPCGDCGDCHPL-- 203
           + H   S      +E  + G   + S P        G   ++  + SP    G   P   
Sbjct: 188 SCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAK 247

Query: 204 ELVVRDSLGGGSA----------------------------DSNLSTPPKRIEPKV--EF 233
           +  V++S    SA                            DS  S+P     P     F
Sbjct: 248 DGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFLPTSGWPF 307

Query: 234 DADEVEVDV-----------GEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLE 282
            + +   D+           GE+ + YA       VEE L  G+A               
Sbjct: 308 SSRDSNADLSVTEASSSDSRGERAELYA------QVEEGLLGGEA--------------- 346

Query: 283 ALLRNSAAPSKDDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSG----------- 331
           + L     P KDDA H  +     R   A ++ +S++ ++AD  G+D             
Sbjct: 347 SYLGPPLTPEKDDALHQATAVANLR--AALMSKNSLLSLKADVLGDDGSLLFEYLPRGAH 404

Query: 332 ----DVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSH 387
               +   V  K  KCP+C ++A  + ILKRH+RSHTGERPYPCE CGK+FTR+EH++ H
Sbjct: 405 SLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRH 464

Query: 388 ALSVHRSNRPIICKGCRRTFTSHLSQGL----RRFGLCDSC 424
            L VH  ++  +CK C R F S  S G+    RR G+C  C
Sbjct: 465 TL-VHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCTDC 504


>gi|157694497 zinc finger and BTB domain containing 10 isoform b
           [Homo sapiens]
          Length = 847

 Score =  125 bits (313), Expect = 1e-28
 Identities = 65/131 (49%), Positives = 89/131 (67%), Gaps = 1/131 (0%)

Query: 5   SYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS-GRH 63
           SY  +LL +LNEQRK+   CD SI+V G+IFKAH+NIL A S +F+ L     ++S  ++
Sbjct: 345 SYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQN 404

Query: 64  STASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLD 123
           +T  LDI     FS+ILDFLYSG L L  +N IEVM+ ASYLQM++VV  C+ +I+ +L+
Sbjct: 405 NTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALN 464

Query: 124 ICRKMEKEAAV 134
           I  K E   +V
Sbjct: 465 ISIKSEAPESV 475



 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 51/156 (32%), Positives = 81/156 (51%), Gaps = 15/156 (9%)

Query: 329 DSGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHA 388
           ++G+  ++  KL KCP C Y AK +  LKRH+  HTG R + C+ CGK FTR+EH++ H+
Sbjct: 687 ENGESSLIMNKL-KCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHS 745

Query: 389 LSVHRSNRPIICKGCRRTFTSHLSQGL----RRFGLCDSCTCVTDTPDDDDDLMPINLSL 444
           L VH+ ++   C  C++ F    S G+    RR+G+C  C          D   P     
Sbjct: 746 L-VHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCA---------DKSQPGGQEG 795

Query: 445 VEASSESQEKSDTDNDWPIYVESGEENDPAGDDSDD 480
           V+   +++   D + +     E+ EE    G+D +D
Sbjct: 796 VDQGQDTEFPRDEEYEENEVGEADEELVDDGEDQND 831


>gi|157694499 zinc finger and BTB domain containing 10 isoform a
           [Homo sapiens]
          Length = 871

 Score =  125 bits (313), Expect = 1e-28
 Identities = 65/131 (49%), Positives = 89/131 (67%), Gaps = 1/131 (0%)

Query: 5   SYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS-GRH 63
           SY  +LL +LNEQRK+   CD SI+V G+IFKAH+NIL A S +F+ L     ++S  ++
Sbjct: 345 SYCYQLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQN 404

Query: 64  STASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLD 123
           +T  LDI     FS+ILDFLYSG L L  +N IEVM+ ASYLQM++VV  C+ +I+ +L+
Sbjct: 405 NTTHLDIAAVQGFSVILDFLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALN 464

Query: 124 ICRKMEKEAAV 134
           I  K E   +V
Sbjct: 465 ISIKSEAPESV 475



 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 51/156 (32%), Positives = 81/156 (51%), Gaps = 15/156 (9%)

Query: 329 DSGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHA 388
           ++G+  ++  KL KCP C Y AK +  LKRH+  HTG R + C+ CGK FTR+EH++ H+
Sbjct: 711 ENGESSLIMNKL-KCPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRHS 769

Query: 389 LSVHRSNRPIICKGCRRTFTSHLSQGL----RRFGLCDSCTCVTDTPDDDDDLMPINLSL 444
           L VH+ ++   C  C++ F    S G+    RR+G+C  C          D   P     
Sbjct: 770 L-VHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCA---------DKSQPGGQEG 819

Query: 445 VEASSESQEKSDTDNDWPIYVESGEENDPAGDDSDD 480
           V+   +++   D + +     E+ EE    G+D +D
Sbjct: 820 VDQGQDTEFPRDEEYEENEVGEADEELVDDGEDQND 855


>gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]
          Length = 522

 Score =  123 bits (309), Expect = 3e-28
 Identities = 136/510 (26%), Positives = 211/510 (41%), Gaps = 114/510 (22%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ME   +   LL  L+EQR + F CDC+++V    F+AHR +L + S YF    + Y    
Sbjct: 1   MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFH---LFYKDQL 57

Query: 61  GRHSTASL--DIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYI 118
            +     L  DIVT+ AF+++L+F+Y GKL      + +V++AASYL M D+V  CK  +
Sbjct: 58  DKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKL 117

Query: 119 R----SSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVD----------------- 157
           +    +  D  +K E  ++ +  V + +  ++  A       D                 
Sbjct: 118 KEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLA 177

Query: 158 -----------SES---PSSGREGTSCGTKS--LVSSPAE-----GEKSVECLRESPCGD 196
                      S+S   P +G E     T +   V+SP        ++SV  +R+S   D
Sbjct: 178 AEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVD 237

Query: 197 CGDCHPLELVVRDSLGG---------GSAD---SNLSTPPKRIEPKVEFDADEVEVDVGE 244
           C     L+L V+ SL G          S D   SNL      ++ KVE +A   E DVG 
Sbjct: 238 C----VLDLSVKSSLSGVENLNSSYFSSQDVLRSNL------VQVKVEKEASCDESDVGT 287

Query: 245 QLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLE-ALLRNSAAPSKDDADHHFSRS 303
                   +  + V+E++ +   V   Y   H+    E ++LR      K   D   +  
Sbjct: 288 N----DYDMEHSTVKESVSTNNRVQ--YEPAHLAPLREDSVLRELDREDKASDDEMMTPE 341

Query: 304 LEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVP-------------------------- 337
            E R +  G   SS++   ++     +G + + P                          
Sbjct: 342 SE-RVQVEGGMESSLLPYVSNIL-SPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGI 399

Query: 338 -------IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALS 390
                  + +  C  C  T      LKRH R+H+GE+PY C  CGK F    +L  HA+ 
Sbjct: 400 RSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAV- 458

Query: 391 VHRSNRPIICKGCRRTFT--SHLSQGLRRF 418
           VH   +P  CK C R FT    L + +R+F
Sbjct: 459 VHTREKPHACKWCERRFTQSGDLYRHIRKF 488


>gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]
          Length = 584

 Score =  123 bits (309), Expect = 3e-28
 Identities = 132/498 (26%), Positives = 203/498 (40%), Gaps = 112/498 (22%)

Query: 10  LLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIH-YIQDSGRHSTASL 68
           +L  LNEQR +   CD  I+VEGR F  HR++L A S YF+ L     + D  + +   +
Sbjct: 20  ILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTSGAVVD--QQNVYEI 77

Query: 69  DIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYI---------- 118
           D V+++A + ++DF Y+  L +   NV +++SAA  L++  V + C   +          
Sbjct: 78  DFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVSHVCADLLDRQILAADAG 137

Query: 119 --RSSLDICRKMEKEAAVAA-------------AVAAAAAAAAAAAAAAAHQVDSESPSS 163
                LD+  ++++   + A             ++  AAAAAAA+   +A     +   +
Sbjct: 138 ADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMNSLPPAAAAAAASFPWSAFGASDDDLDA 197

Query: 164 GREGTSCGTKSLVSSPAEGEKSVECLRESPCGDCGDCHPLEL------VVRDSLGGGS-A 216
            +E  +    ++ +                    GDC+ L+         R   G G   
Sbjct: 198 TKEAVAAAVAAVAA--------------------GDCNGLDFYGPGPPAERPPTGDGDEG 237

Query: 217 DSNLSTPPKRIE---------PKVEFDADEVEVDVGEQLQQYAAPLNLAHVEEA----LP 263
           DSN    P+R E         P V   A       G   ++ AA L+ A  E        
Sbjct: 238 DSNPGLWPERDEDAPTGGLFPPPVAPPAATQNGHYGRGGEEEAASLSEAAPEPGDSPGFL 297

Query: 264 SGQA---------VDLAYSNYHVKQFLEALLRNSAAPSKDDADHHFSRSLEGRPEGAGVA 314
           SG A         VD   ++  ++Q + ++ R  AA    D         E R +  GV 
Sbjct: 298 SGAAEGEDGDGPDVDGLAASTLLQQMMSSVGRAGAAAGDSDE--------ESRADDKGV- 348

Query: 315 MSSMMDVQADWY-GEDSGDVL----------VVPIKLHKCPFCPYTAKQKGILKRHIRSH 363
               MD    ++ G   GDV           +      KCP C    +  G L RHIR+H
Sbjct: 349 ----MDYYLKYFSGAHDGDVYPAWSQKVEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTH 404

Query: 364 TGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTSH--------LSQGL 415
           TGE+PY C  C  RFTRQ+ L+ H +  H   +P +C+ C   F  +        +  GL
Sbjct: 405 TGEKPYECNICKVRFTRQDKLKVH-MRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGL 463

Query: 416 RRFGLCDSCTCVTDTPDD 433
           R +  CDSC C T    D
Sbjct: 464 RPY-QCDSC-CKTFVRSD 479



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 42/138 (30%), Positives = 51/138 (36%), Gaps = 30/138 (21%)

Query: 347 PYTAKQKGI-------LKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPII 399
           PY  +Q G        LK H+R HTG RPY C++C K F R +HL  H            
Sbjct: 437 PYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDHLHRHLKK--------- 487

Query: 400 CKGCRRTFTSHLSQGLRRFGLCDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTDN 459
             GC    +    +   R G  D     T TP       P   S  +A    QEK   D 
Sbjct: 488 -DGCNGVPSRRGRKPRVRGGAPDPSPGATATPG-----APAQPSSPDARRNGQEKHFKDE 541

Query: 460 DWPIYVESGEENDPAGDD 477
           D        E+ D A  D
Sbjct: 542 D--------EDEDVASPD 551


>gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]
          Length = 531

 Score =  123 bits (309), Expect = 3e-28
 Identities = 136/510 (26%), Positives = 211/510 (41%), Gaps = 114/510 (22%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ME   +   LL  L+EQR + F CDC+++V    F+AHR +L + S YF    + Y    
Sbjct: 10  MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFH---LFYKDQL 66

Query: 61  GRHSTASL--DIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYI 118
            +     L  DIVT+ AF+++L+F+Y GKL      + +V++AASYL M D+V  CK  +
Sbjct: 67  DKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKL 126

Query: 119 R----SSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVD----------------- 157
           +    +  D  +K E  ++ +  V + +  ++  A       D                 
Sbjct: 127 KEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLA 186

Query: 158 -----------SES---PSSGREGTSCGTKS--LVSSPAE-----GEKSVECLRESPCGD 196
                      S+S   P +G E     T +   V+SP        ++SV  +R+S   D
Sbjct: 187 AEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVD 246

Query: 197 CGDCHPLELVVRDSLGG---------GSAD---SNLSTPPKRIEPKVEFDADEVEVDVGE 244
           C     L+L V+ SL G          S D   SNL      ++ KVE +A   E DVG 
Sbjct: 247 C----VLDLSVKSSLSGVENLNSSYFSSQDVLRSNL------VQVKVEKEASCDESDVGT 296

Query: 245 QLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLE-ALLRNSAAPSKDDADHHFSRS 303
                   +  + V+E++ +   V   Y   H+    E ++LR      K   D   +  
Sbjct: 297 N----DYDMEHSTVKESVSTNNRVQ--YEPAHLAPLREDSVLRELDREDKASDDEMMTPE 350

Query: 304 LEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVP-------------------------- 337
            E R +  G   SS++   ++     +G + + P                          
Sbjct: 351 SE-RVQVEGGMESSLLPYVSNIL-SPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGI 408

Query: 338 -------IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALS 390
                  + +  C  C  T      LKRH R+H+GE+PY C  CGK F    +L  HA+ 
Sbjct: 409 RSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAV- 467

Query: 391 VHRSNRPIICKGCRRTFT--SHLSQGLRRF 418
           VH   +P  CK C R FT    L + +R+F
Sbjct: 468 VHTREKPHACKWCERRFTQSGDLYRHIRKF 497


>gi|167234429 zinc finger and BTB domain containing 17 [Homo
           sapiens]
          Length = 803

 Score =  120 bits (302), Expect = 2e-27
 Identities = 105/418 (25%), Positives = 176/418 (42%), Gaps = 58/418 (13%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           M+   +   +L +LN+QR+    CDC+ +V+G  FKAH+ +L A S YF+ L +      
Sbjct: 1   MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVD----- 55

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFC---KTY 117
            +     LDI  +     +L+F+Y+ KL L  ENV +V++ A++LQM D++  C   K+ 
Sbjct: 56  -QKDVVHLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSL 114

Query: 118 IRSSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESP---SSGREGTSCGTKS 174
              +       E  A       A     A +  +   Q    +P   S   +    G   
Sbjct: 115 AEPATSPGGNAEALATEGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEERGGQAQ 174

Query: 175 LVSSPAEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSAD-----SNLSTPPKRIEP 229
             +S AE  +  +  RE P        P+EL    + G  +A+     S  S     +EP
Sbjct: 175 SAASGAEQTEKADAPREPP--------PVELKPDPTSGMAAAEAEAALSESSEQEMEVEP 226

Query: 230 KVEFDADEVEVDVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSA 289
             + + ++ E +  EQ ++ A P   A V+E                      + L N  
Sbjct: 227 ARKGEEEQKEQE--EQEEEGAGP---AEVKEE--------------------GSQLENGE 261

Query: 290 APSKDDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYT 349
           AP +++ +        G   G  +  S    +++  YG+ +       + +HKC  C   
Sbjct: 262 APEENENEES-----AGTDSGQELG-SEARGLRSGTYGDRTESKAYGSV-IHKCEDCGKE 314

Query: 350 AKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTF 407
               G  KRHIR HTGE+P+ C  C K F+     ++H    H   +P  C+ C +++
Sbjct: 315 FTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHE-KTHSPLKPYGCEECGKSY 371



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 28/69 (40%), Positives = 38/69 (55%), Gaps = 1/69 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K HKCP C     Q G LK H++ H  + P  C  CGK+FT   +L+ H L +H   +P 
Sbjct: 444 KEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRH-LRIHSGEKPY 502

Query: 399 ICKGCRRTF 407
           +C  C+R F
Sbjct: 503 VCIHCQRQF 511



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 27/61 (44%), Positives = 36/61 (59%)

Query: 338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRP 397
           I+ HKC  C       G L +HI  HTGE+PY C+ CG+ F R ++LRSH  +VH+    
Sbjct: 583 IRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAG 642

Query: 398 I 398
           I
Sbjct: 643 I 643



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 33/90 (36%), Positives = 45/90 (50%), Gaps = 8/90 (8%)

Query: 342 KCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICK 401
           +C  C     Q   L  H+R HTGE+PY CE CGKRF +   L +H +  H + RP  C 
Sbjct: 531 QCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANH-IRHHDNIRPHKCS 589

Query: 402 GCRRTFTS--HLSQGL-----RRFGLCDSC 424
            C + F +   LS+ +      +  LCD C
Sbjct: 590 VCSKAFVNVGDLSKHIIIHTGEKPYLCDKC 619



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 3/80 (3%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K + C  C       G L+RH+R HTGE+P  C  CGK FT+   L +H +  H   +P 
Sbjct: 500 KPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAH-VRQHTGEKPY 558

Query: 399 ICKGCRRTF--TSHLSQGLR 416
           +C+ C + F  +S L+  +R
Sbjct: 559 VCERCGKRFVQSSQLANHIR 578



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 1/67 (1%)

Query: 342 KCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICK 401
           KC  C       G LKRH+R H+GE+PY C  C ++F     L+ H + +H   +P  C 
Sbjct: 475 KCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRH-VRIHTGEKPCQCV 533

Query: 402 GCRRTFT 408
            C + FT
Sbjct: 534 MCGKAFT 540



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 19/71 (26%), Positives = 40/71 (56%), Gaps = 1/71 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K ++C +C  +        RH+ +H  ++ + C  C K+F +  +L++H L +H ++ P+
Sbjct: 416 KPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAH-LKIHIADGPL 474

Query: 399 ICKGCRRTFTS 409
            C+ C + FT+
Sbjct: 475 KCRECGKQFTT 485



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 1/69 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K + C  C     Q   L  HIR H   RP+ C  C K F     L  H + +H   +P 
Sbjct: 556 KPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHII-IHTGEKPY 614

Query: 399 ICKGCRRTF 407
           +C  C R F
Sbjct: 615 LCDKCGRGF 623


>gi|8923885 myoneurin [Homo sapiens]
          Length = 610

 Score =  112 bits (281), Expect = 6e-25
 Identities = 109/439 (24%), Positives = 184/439 (41%), Gaps = 62/439 (14%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           M+   +   LL  LN+QR+  F CDC+I++    FKAHRN+L + S YF A+   Y   S
Sbjct: 1   MQYSHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLASFSEYFGAI---YRSTS 57

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS 120
             +       V +D F  +L+F+Y+G L+L   NV E+  AA YL++ +VV  CK     
Sbjct: 58  ENNVFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKCKI---- 113

Query: 121 SLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQ-VDSESPSSGREGTSCGTKSLVSSP 179
                 KME  A +A   +   ++            + +    + RE +   T  + ++P
Sbjct: 114 ------KMEDFAFIANPSSTEISSITGNIELNQQTCLLTLRDYNNREKSEVSTDLIQANP 167

Query: 180 AEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVE 239
            +G                       + + S          ++P       V++ +D +E
Sbjct: 168 KQG----------------------ALAKKSSQTKKKKKAFNSPKTGQNKTVQYPSDILE 205

Query: 240 VDVGEQLQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHH 299
                      A + L      LP+     +A  N + +  L +++ N+  P++D     
Sbjct: 206 ----------NASVELFLDANKLPTPVVEQVAQINDNSELELTSVVENT-FPAQDIVHTV 254

Query: 300 FSRSLEGRPEGAGV----AMSSMMDVQADWYGEDSGDVLVVPIKLHK--CPFCPYTAKQK 353
             +   G+ +        +MS++  V++ +  E+SG+ L       K  C  C     + 
Sbjct: 255 TVKRKRGKSQPNCALKEHSMSNIASVKSPYEAENSGEELDQRYSKAKPMCNTCGKVFSEA 314

Query: 354 GILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIIC----KG----CRR 405
             L+RH+R H G +PY C  CGK FT+   L++H +  H   +P  C    KG    C+ 
Sbjct: 315 SSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTH-VRTHTGEKPYKCELCDKGFAQKCQL 373

Query: 406 TFTSHLSQGLRRFGLCDSC 424
            F S +  G  +   CD C
Sbjct: 374 VFHSRMHHGEEKPYKCDVC 392



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 28/71 (39%), Positives = 37/71 (52%), Gaps = 1/71 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K + C  C     Q   L  H+R HTGE+PY C+TCGK F     L +H+   H   +P 
Sbjct: 413 KPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRK-HTGEKPY 471

Query: 399 ICKGCRRTFTS 409
           IC  C ++F S
Sbjct: 472 ICGICGKSFIS 482



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 7/94 (7%)

Query: 338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRP 397
           +K + C  C     Q   LK H+R+HTGE+PY CE C K F ++  L  H+   H   +P
Sbjct: 327 VKPYVCHLCGKAFTQCNQLKTHVRTHTGEKPYKCELCDKGFAQKCQLVFHSRMHHGEEKP 386

Query: 398 IICKGCRRTF--TSHLSQGLRRFG-----LCDSC 424
             C  C   F  +S+L    R+       +CD C
Sbjct: 387 YKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRC 420



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K +KC  C         LK H R H+GE+PY C+ CG+RF +   L  H +  H   +P 
Sbjct: 385 KPYKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYH-VRRHTGEKPY 443

Query: 399 ICKGCRRTF 407
           +C  C + F
Sbjct: 444 VCDTCGKAF 452



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 36/133 (27%), Positives = 53/133 (39%), Gaps = 1/133 (0%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K + C  C         L  H R HTGE+PY C  CGK F     L  H  S H   RP 
Sbjct: 441 KPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRS-HTGERPF 499

Query: 399 ICKGCRRTFTSHLSQGLRRFGLCDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTD 458
           IC+ C  ++T   +    +  +        D+  +D  L   +       SE+ +   +D
Sbjct: 500 ICELCGNSYTDIKNLKKHKTKVHSGADKTLDSSAEDHTLSEQDSIQKSPLSETMDVKPSD 559

Query: 459 NDWPIYVESGEEN 471
              P+ +  G E+
Sbjct: 560 MTLPLALPLGTED 572


>gi|14670366 POZ (BTB) and AT hook containing zinc finger 1 long B
           isoform [Homo sapiens]
          Length = 537

 Score =  101 bits (252), Expect = 1e-21
 Identities = 117/466 (25%), Positives = 173/466 (37%), Gaps = 88/466 (18%)

Query: 2   EMQSYYAKLLGELNEQRKRDF-FCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ++  +  ++L  LN+QRK    FCD  + V    F AHR +L A S YF ++    + D 
Sbjct: 18  QVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDG 77

Query: 61  GRHSTASLDI---------------------VTSDAFSIILDFLYSGKLDLCGENVIEVM 99
           G       D+                     ++S  F  ILDF Y+ ++ +  E+  E+M
Sbjct: 78  GAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELM 137

Query: 100 SAASYLQMNDVVNFCKTYIRSS-----------------------LDICRKMEKEAAVAA 136
           +AA +L M  V+  C+  I+ S                       L     M   AA+AA
Sbjct: 138 TAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAA 197

Query: 137 AVAAAA--------AAAAAAAAAAAHQVDSESPSSGREGTSCGTKS--LVSSPAEGEKSV 186
                A        AA AA AA A        P   R     G  S  L++SP     SV
Sbjct: 198 NSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFP---SV 254

Query: 187 ECLRESPCGDCGDCHPLELVVRDSLGGGSAD-SNLSTPPKRIEPKVEFDADEVEVDVGEQ 245
                   G  G   P +  + DS+ G           P  +  KV  DA+ +      +
Sbjct: 255 ASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQ---HE 311

Query: 246 LQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHFSRSLE 305
            Q     L L +++   P                     L  +  P  +D D    RS  
Sbjct: 312 AQHGVTSLQLGYIDLPPPR--------------------LGENGLPISEDPDGPRKRSRT 351

Query: 306 GRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTG 365
            +     +      DV    Y  +   +     K + CP C    K+K  +  H+RSH G
Sbjct: 352 RKQVACEICGKIFRDV----YHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDG 407

Query: 366 E--RPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTS 409
              +PY C++CGK F+R +HL  H   VH S RP  C+ C  +F +
Sbjct: 408 SVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFAT 453



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 15/102 (14%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQE----HLRSHALSVHRSNRPI 398
           C  C    +    L RH  SH+GE+PY C  CG RF R++    H+RSH  SV    +P 
Sbjct: 357 CEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSV---GKPY 413

Query: 399 ICKGCRRTFT--SHLSQGLR------RFGLCDSCTCVTDTPD 432
           IC+ C + F+   HL+  ++      R   C +C     T D
Sbjct: 414 ICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRD 455


>gi|14670362 POZ (BTB) and AT hook containing zinc finger 1 long A
           isoform [Homo sapiens]
          Length = 641

 Score =  101 bits (252), Expect = 1e-21
 Identities = 117/466 (25%), Positives = 173/466 (37%), Gaps = 88/466 (18%)

Query: 2   EMQSYYAKLLGELNEQRKRDF-FCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ++  +  ++L  LN+QRK    FCD  + V    F AHR +L A S YF ++    + D 
Sbjct: 18  QVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDG 77

Query: 61  GRHSTASLDI---------------------VTSDAFSIILDFLYSGKLDLCGENVIEVM 99
           G       D+                     ++S  F  ILDF Y+ ++ +  E+  E+M
Sbjct: 78  GAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELM 137

Query: 100 SAASYLQMNDVVNFCKTYIRSS-----------------------LDICRKMEKEAAVAA 136
           +AA +L M  V+  C+  I+ S                       L     M   AA+AA
Sbjct: 138 TAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAA 197

Query: 137 AVAAAA--------AAAAAAAAAAAHQVDSESPSSGREGTSCGTKS--LVSSPAEGEKSV 186
                A        AA AA AA A        P   R     G  S  L++SP     SV
Sbjct: 198 NSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFP---SV 254

Query: 187 ECLRESPCGDCGDCHPLELVVRDSLGGGSAD-SNLSTPPKRIEPKVEFDADEVEVDVGEQ 245
                   G  G   P +  + DS+ G           P  +  KV  DA+ +      +
Sbjct: 255 ASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQ---HE 311

Query: 246 LQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHFSRSLE 305
            Q     L L +++   P                     L  +  P  +D D    RS  
Sbjct: 312 AQHGVTSLQLGYIDLPPPR--------------------LGENGLPISEDPDGPRKRSRT 351

Query: 306 GRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTG 365
            +     +      DV    Y  +   +     K + CP C    K+K  +  H+RSH G
Sbjct: 352 RKQVACEICGKIFRDV----YHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDG 407

Query: 366 E--RPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTS 409
              +PY C++CGK F+R +HL  H   VH S RP  C+ C  +F +
Sbjct: 408 SVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFAT 453



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 15/102 (14%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQE----HLRSHALSVHRSNRPI 398
           C  C    +    L RH  SH+GE+PY C  CG RF R++    H+RSH  SV    +P 
Sbjct: 357 CEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSV---GKPY 413

Query: 399 ICKGCRRTFT--SHLSQGLR------RFGLCDSCTCVTDTPD 432
           IC+ C + F+   HL+  ++      R   C +C     T D
Sbjct: 414 ICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRD 455



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 12/28 (42%), Positives = 15/28 (53%)

Query: 365 GERPYPCETCGKRFTRQEHLRSHALSVH 392
           GE+ YPC  CG  F  + +L  H   VH
Sbjct: 555 GEKKYPCPECGSFFRSKSYLNKHIQKVH 582


>gi|14670360 POZ (BTB) and AT hook containing zinc finger 1 long C
           isoform [Homo sapiens]
          Length = 687

 Score =  101 bits (252), Expect = 1e-21
 Identities = 117/466 (25%), Positives = 173/466 (37%), Gaps = 88/466 (18%)

Query: 2   EMQSYYAKLLGELNEQRKRDF-FCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ++  +  ++L  LN+QRK    FCD  + V    F AHR +L A S YF ++    + D 
Sbjct: 18  QVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDG 77

Query: 61  GRHSTASLDI---------------------VTSDAFSIILDFLYSGKLDLCGENVIEVM 99
           G       D+                     ++S  F  ILDF Y+ ++ +  E+  E+M
Sbjct: 78  GAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELM 137

Query: 100 SAASYLQMNDVVNFCKTYIRSS-----------------------LDICRKMEKEAAVAA 136
           +AA +L M  V+  C+  I+ S                       L     M   AA+AA
Sbjct: 138 TAAKFLLMRSVIEICQEVIKQSNVQILVPPARADIMLFRPPGTSDLGFPLDMTNGAALAA 197

Query: 137 AVAAAA--------AAAAAAAAAAAHQVDSESPSSGREGTSCGTKS--LVSSPAEGEKSV 186
                A        AA AA AA A        P   R     G  S  L++SP     SV
Sbjct: 198 NSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFP---SV 254

Query: 187 ECLRESPCGDCGDCHPLELVVRDSLGGGSAD-SNLSTPPKRIEPKVEFDADEVEVDVGEQ 245
                   G  G   P +  + DS+ G           P  +  KV  DA+ +      +
Sbjct: 255 ASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQ---HE 311

Query: 246 LQQYAAPLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHFSRSLE 305
            Q     L L +++   P                     L  +  P  +D D    RS  
Sbjct: 312 AQHGVTSLQLGYIDLPPPR--------------------LGENGLPISEDPDGPRKRSRT 351

Query: 306 GRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHIRSHTG 365
            +     +      DV    Y  +   +     K + CP C    K+K  +  H+RSH G
Sbjct: 352 RKQVACEICGKIFRDV----YHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDG 407

Query: 366 E--RPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFTS 409
              +PY C++CGK F+R +HL  H   VH S RP  C+ C  +F +
Sbjct: 408 SVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFAT 453



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 35/102 (34%), Positives = 49/102 (48%), Gaps = 15/102 (14%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQE----HLRSHALSVHRSNRPI 398
           C  C    +    L RH  SH+GE+PY C  CG RF R++    H+RSH  SV    +P 
Sbjct: 357 CEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSV---GKPY 413

Query: 399 ICKGCRRTFT--SHLSQGLR------RFGLCDSCTCVTDTPD 432
           IC+ C + F+   HL+  ++      R   C +C     T D
Sbjct: 414 ICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRD 455



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 12/28 (42%), Positives = 15/28 (53%)

Query: 365 GERPYPCETCGKRFTRQEHLRSHALSVH 392
           GE+ YPC  CG  F  + +L  H   VH
Sbjct: 601 GEKKYPCPECGSFFRSKSYLNKHIQKVH 628


>gi|109134351 zinc finger and BTB domain containing 44 [Homo
           sapiens]
          Length = 453

 Score =  100 bits (250), Expect = 2e-21
 Identities = 110/454 (24%), Positives = 180/454 (39%), Gaps = 60/454 (13%)

Query: 5   SYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHS 64
           S+  ++LG+LN  R    FCD +I V+ +IF+AH+ +L A S +FR  L+   +D  + +
Sbjct: 12  SHSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENK-N 70

Query: 65  TASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSS-LD 123
              L  VT   F  +L++ Y+  L +  EN+I+V++AASY+QM  V + C  +++SS L 
Sbjct: 71  VLDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVASTCSEFMKSSILW 130

Query: 124 ICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSPAEGE 183
                + E  + A     +     +   +   V SE     R    C       S  + +
Sbjct: 131 NTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCR-----ESRRKRK 185

Query: 184 KSVECLRESPCGDCGDCHPLELVVRDSLG-----GGSADSNLSTP-------PKRIEPKV 231
             +    ESP   CG       V+  S           DS+L+ P        +RI+P+ 
Sbjct: 186 SYIVMSPESPV-KCGTQTSSPQVLNSSASYSENRNQPVDSSLAFPWTFPFGIDRRIQPEK 244

Query: 232 EFDADEVEV-------DVGEQLQQYAAPLNLAHVEEALPSGQAVD-------LAYSNYH- 276
              A+           + G ++  Y   +     +  LP G   D       L+    H 
Sbjct: 245 VKQAENTRTLELPGPSETGRRMADY---VTCESTKTTLPLGTEEDVRVKVERLSDEEVHE 301

Query: 277 -----VKQFLEALLRNSAAPSKDDADHHF-----SRSLEGRPEGAGVAMSSMMDVQADWY 326
                V     +L      P  +           S S+    EG    + ++    +   
Sbjct: 302 EVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTLQSTSSTNA 361

Query: 327 GEDSGDVL---VVPIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEH 383
             D  D L     P +L+  P    T +           +  +RP+ C TCG RFTR ++
Sbjct: 362 PPDDDDRLENVQYPYQLYIAPSTSSTERPS--------PNGPDRPFQCPTCGVRFTRIQN 413

Query: 384 LRSHALSVHRSNRPIICKGCRRTFTSHLSQGLRR 417
           L+ H L +H   +P  C  C + FT   S  + R
Sbjct: 414 LKQHML-IHSGIKPFQCDRCGKKFTRAYSLKMHR 446



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 20/53 (37%), Positives = 31/53 (58%)

Query: 337 PIKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHAL 389
           P +  +CP C     +   LK+H+  H+G +P+ C+ CGK+FTR   L+ H L
Sbjct: 395 PDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMHRL 447


>gi|209413766 zinc finger and BTB domain containing 43 [Homo
           sapiens]
          Length = 467

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 115/467 (24%), Positives = 181/467 (38%), Gaps = 99/467 (21%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           +E   + + +L +LN+QR++   CD SI+V+G IF+AH+ +L A+S YF   ++  +++S
Sbjct: 10  VEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCDQVL--LKNS 67

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS 120
            R      D++    F  IL   Y+G+L +    ++  ++AAS+LQM  VV+ C   +  
Sbjct: 68  RR--IVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEG 125

Query: 121 SLDI-CRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSP 179
           +  + C+K+                         H  D +SPSS        +  L S  
Sbjct: 126 NPTVLCQKLN------------------------HGSDHQSPSSSSYNGLVESFELGSGG 161

Query: 180 AEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSAD-----SNLSTPPKRIEPKV-EF 233
                  + LR        D    E   +D L     +     SN ST   R+  ++   
Sbjct: 162 HTDFPKAQELR--------DGENEEESTKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQ 213

Query: 234 DADEVEVDVGE---QLQQYAAPLNLAHVE---------EALPSGQAVDLAYSNYHVKQFL 281
           D +E   D  E       Y+ P  +AH           E    G  V   Y  + V + +
Sbjct: 214 DGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVKPERLEQACEGMDVHATYDEHQVTESI 273

Query: 282 EAL-LRNSAAPSKDDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYG----EDSGD---- 332
             +   ++  PS  + D H     +   E    A  S  D Q D+YG    E SG+    
Sbjct: 274 NTVQTEHTVQPSGVEEDFHIGEK-KVEAEFDEQADESNYDEQVDFYGSSMEEFSGERSDG 332

Query: 333 -------------------VLVVPI-------------KLHKCPFCPYTAKQKGILKRHI 360
                               +V  I             KL+ C  C  +   K    RH+
Sbjct: 333 NLIGHRQEAALAAGYSENIEMVTGIKEEASHLGFSATDKLYPCQ-CGKSFTHKSQRDRHM 391

Query: 361 RSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTF 407
             H G RPY C  CGK+F  + HL  H + +H   +P  C  C + F
Sbjct: 392 SMHLGLRPYGCGVCGKKFKMKHHLVGH-MKIHTGIKPYECNICAKRF 437



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 19/57 (33%), Positives = 28/57 (49%)

Query: 338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRS 394
           ++ + C  C    K K  L  H++ HTG +PY C  C KRF  ++    H  S  +S
Sbjct: 397 LRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKS 453


>gi|7662100 zinc finger and BTB domain containing 43 [Homo sapiens]
          Length = 467

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 115/467 (24%), Positives = 181/467 (38%), Gaps = 99/467 (21%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           +E   + + +L +LN+QR++   CD SI+V+G IF+AH+ +L A+S YF   ++  +++S
Sbjct: 10  VEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCDQVL--LKNS 67

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRS 120
            R      D++    F  IL   Y+G+L +    ++  ++AAS+LQM  VV+ C   +  
Sbjct: 68  RR--IVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCTEVLEG 125

Query: 121 SLDI-CRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPSSGREGTSCGTKSLVSSP 179
           +  + C+K+                         H  D +SPSS        +  L S  
Sbjct: 126 NPTVLCQKLN------------------------HGSDHQSPSSSSYNGLVESFELGSGG 161

Query: 180 AEGEKSVECLRESPCGDCGDCHPLELVVRDSLGGGSAD-----SNLSTPPKRIEPKV-EF 233
                  + LR        D    E   +D L     +     SN ST   R+  ++   
Sbjct: 162 HTDFPKAQELR--------DGENEEESTKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQ 213

Query: 234 DADEVEVDVGE---QLQQYAAPLNLAHVE---------EALPSGQAVDLAYSNYHVKQFL 281
           D +E   D  E       Y+ P  +AH           E    G  V   Y  + V + +
Sbjct: 214 DGEEGASDSAEFHYTRPMYSKPSIMAHKRWIHVKPERLEQACEGMDVHATYDEHQVTESI 273

Query: 282 EAL-LRNSAAPSKDDADHHFSRSLEGRPEGAGVAMSSMMDVQADWYG----EDSGD---- 332
             +   ++  PS  + D H     +   E    A  S  D Q D+YG    E SG+    
Sbjct: 274 NTVQTEHTVQPSGVEEDFHIGEK-KVEAEFDEQADESNYDEQVDFYGSSMEEFSGERSDG 332

Query: 333 -------------------VLVVPI-------------KLHKCPFCPYTAKQKGILKRHI 360
                               +V  I             KL+ C  C  +   K    RH+
Sbjct: 333 NLIGHRQEAALAAGYSENIEMVTGIKEEASHLGFSATDKLYPCQ-CGKSFTHKSQRDRHM 391

Query: 361 RSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTF 407
             H G RPY C  CGK+F  + HL  H + +H   +P  C  C + F
Sbjct: 392 SMHLGLRPYGCGVCGKKFKMKHHLVGH-MKIHTGIKPYECNICAKRF 437



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 19/57 (33%), Positives = 28/57 (49%)

Query: 338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRS 394
           ++ + C  C    K K  L  H++ HTG +PY C  C KRF  ++    H  S  +S
Sbjct: 397 LRPYGCGVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKRFMWRDSFHRHVTSCTKS 453


>gi|212286156 zinc finger and BTB domain containing 42 [Homo
           sapiens]
          Length = 422

 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 52/117 (44%), Positives = 71/117 (60%), Gaps = 4/117 (3%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ME   +  +LLG L +QR+  F CDC+++V    F AHR +L A S YF   L +  + +
Sbjct: 1   MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFH--LFYRDRPA 58

Query: 61  GRHSTASL--DIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCK 115
           G   T  L  DIVT+ AF  +LDF+Y G+LDL    V +V++AASYL M D+V  CK
Sbjct: 59  GSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCK 115



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 3/78 (3%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKG 402
           CP C  T      LKRH R+H+GE+PY C  CGK F    +L  H + VH   +P  C+ 
Sbjct: 336 CPLCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTV-VHTREKPHACRW 394

Query: 403 CRRTFT--SHLSQGLRRF 418
           C R FT    L + +R+F
Sbjct: 395 CERRFTQSGDLYRHVRKF 412



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 18/54 (33%), Positives = 25/54 (46%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVH 392
           K + C  C  + +    L RH   HT E+P+ C  C +RFT+   L  H    H
Sbjct: 360 KPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFTQSGDLYRHVRKFH 413


>gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]
          Length = 574

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 62/185 (33%), Positives = 92/185 (49%), Gaps = 24/185 (12%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ME   +  +LL  L EQR + F CDC+++V    F AHR +L + S +F+        D 
Sbjct: 51  MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIE-VMSAASYLQMNDVVNFCKTYIR 119
                   +IVT+ AF ++LDF+Y+G+L L G+  +E V++AASYL MND+V  CK  ++
Sbjct: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170

Query: 120 SSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPS-SGREGTSCGTK-SLVS 177
                                A A A A +     + +S+ PS      TS GT+ SL S
Sbjct: 171 ---------------------ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLAS 209

Query: 178 SPAEG 182
           +   G
Sbjct: 210 AETSG 214



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 18/53 (33%), Positives = 23/53 (43%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSN 395
           C  C  T      L+RH   HT ERPY C  C + +T+   L  H    H  +
Sbjct: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNED 526



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 18/38 (47%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 371 CETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFT 408
           C+TCGK F+    LR HA +VH   RP  C+ C R++T
Sbjct: 474 CKTCGKTFSCSYTLRRHA-TVHTRERPYECRYCLRSYT 510


>gi|139394599 hypermethylated in cancer 2 [Homo sapiens]
          Length = 615

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 49/123 (39%), Positives = 77/123 (62%), Gaps = 9/123 (7%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ME+ S+  +LL +LN+QR + F CD  I+VE  IF+AH+N+L A+S YF++L++H     
Sbjct: 23  MELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLH----- 77

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKL---DLCGE-NVIEVMSAASYLQMNDVVNFCKT 116
                   D+V+S  F  ILDF+Y+GKL   D   E N   +++AASYLQ+ ++   C+ 
Sbjct: 78  DNLINLDTDMVSSTVFQQILDFIYTGKLLPSDQPAEPNFSTLLTAASYLQLPELAALCRR 137

Query: 117 YIR 119
            ++
Sbjct: 138 KLK 140



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 28/66 (42%), Positives = 37/66 (56%), Gaps = 1/66 (1%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKG 402
           C  C     Q+G + RH+RSH G +P+ C+ CG RFTRQ  L  H + VH   +P  C+ 
Sbjct: 535 CNICGKMFTQRGTMTRHMRSHLGLKPFACDECGMRFTRQYRLTEH-MRVHSGEKPYECQL 593

Query: 403 CRRTFT 408
           C   FT
Sbjct: 594 CGGKFT 599



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)

Query: 299 HFSRSLEGRPEGAGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKR 358
           H    L  + EGA    S   + +A+     S      P +  KC  C  T K    L++
Sbjct: 464 HTEEELFIKEEGAYETGSGGAEEEAEDLSAPSAAYTAEP-RPFKCSVCEKTYKDPATLRQ 522

Query: 359 HIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFT 408
           H ++H   RP+PC  CGK FT++  +  H  S H   +P  C  C   FT
Sbjct: 523 HEKTHWLTRPFPCNICGKMFTQRGTMTRHMRS-HLGLKPFACDECGMRFT 571



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 23/57 (40%), Positives = 34/57 (59%), Gaps = 1/57 (1%)

Query: 338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRS 394
           +K   C  C     ++  L  H+R H+GE+PY C+ CG +FT+Q +L SH L +H S
Sbjct: 558 LKPFACDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISH-LRMHTS 613


>gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]
          Length = 677

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 45/119 (37%), Positives = 71/119 (59%), Gaps = 1/119 (0%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           M+   ++ ++  +LN QR     CDC I+V  R FKAHR++L A S +FRAL      D 
Sbjct: 1   MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQ 60

Query: 61  GRHS-TASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYI 118
             +      ++VT++AF+ ++D +Y+  L L   NV++V+ AAS+L +N VV  CK Y+
Sbjct: 61  TMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYL 119



 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 26/58 (44%), Positives = 34/58 (58%), Gaps = 1/58 (1%)

Query: 332 DVLVVP-IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHA 388
           +VLVV   + + C  C  T       K+HIR HTGE+PY C  CGKRF++  HL  H+
Sbjct: 603 NVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHS 660



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 18/62 (29%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 352 QKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTF--TS 409
           +K + + ++    G R Y C+ C K F      + H + VH   +P  C  C + F  +S
Sbjct: 596 KKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKH-IRVHTGEKPYACLKCGKRFSQSS 654

Query: 410 HL 411
           HL
Sbjct: 655 HL 656


>gi|223972645 zinc finger protein 509 [Homo sapiens]
          Length = 765

 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 42/112 (37%), Positives = 69/112 (61%), Gaps = 2/112 (1%)

Query: 10  LLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASLD 69
           LL +L+EQR +   CDC ++V+G  FKAH+N+L A S YFR+L  +    S ++    LD
Sbjct: 11  LLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRSLFQN--SSSQKNDVFHLD 68

Query: 70  IVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSS 121
           +        ILDF+Y+  LDL  +N+  ++  A  LQ+ +V++ C T+++S+
Sbjct: 69  VKNVSGIGQILDFMYTSHLDLNQDNIQVMLDTAQCLQVQNVLSLCHTFLKSA 120



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 27/71 (38%), Positives = 40/71 (56%), Gaps = 1/71 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K  +C  C     Q G L+ H+R H+GE+PY CE CGKRF     ++ H + +H   +P 
Sbjct: 421 KPFECNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASGDVQRHII-IHSGEKPH 479

Query: 399 ICKGCRRTFTS 409
           +C  C R F++
Sbjct: 480 LCDICGRGFSN 490



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 26/69 (37%), Positives = 39/69 (56%), Gaps = 1/69 (1%)

Query: 341 HKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIIC 400
           + C  C    K    L+ H RSHTGE+P+ C  CGK F++  +L++H L  H   +P IC
Sbjct: 395 YACELCGKPFKHPSNLELHKRSHTGEKPFECNICGKHFSQAGNLQTH-LRRHSGEKPYIC 453

Query: 401 KGCRRTFTS 409
           + C + F +
Sbjct: 454 EICGKRFAA 462



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 41/148 (27%), Positives = 61/148 (41%), Gaps = 10/148 (6%)

Query: 341 HKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIIC 400
           + C  C       G L+RH+R+HTGE+PY CE C K FTR   LR H        + + C
Sbjct: 535 YSCSACGKCFGGSGDLRRHVRTHTGEKPYTCEICNKCFTRSAVLRRH--------KKMHC 586

Query: 401 KGCRRT--FTSHLSQGLRRFGLCDSCTCVTDTPDDDDDLMPINLSLVEASSESQEKSDTD 458
           K    +      LSQ +    L  S +  + + D    LMP+++ L     E+       
Sbjct: 587 KAGDESPDVLEELSQAIETSDLEKSQSSDSFSQDTSVTLMPVSVKLPVHPVENSVAEFDS 646

Query: 459 NDWPIYVESGEENDPAGDDSDDKPQIQP 486
           +    Y +      P G    +K  + P
Sbjct: 647 HSGGSYCKLRSMIQPHGVSDQEKLSLDP 674



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 54/171 (31%), Positives = 77/171 (45%), Gaps = 18/171 (10%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K+  C  C  +   +  L +H   HTGERPY C  CGK F     LR H +  H   +P 
Sbjct: 505 KVFTCDECGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFGGSGDLRRH-VRTHTGEKPY 563

Query: 399 ICKGCRRTFTSHLSQGLRRFGLCDSCTCVTDTPDDDDDL-MPINLSLVE--ASSESQEKS 455
            C+ C + FT   S  LRR      C    ++PD  ++L   I  S +E   SS+S  + 
Sbjct: 564 TCEICNKCFTR--SAVLRRHKKM-HCKAGDESPDVLEELSQAIETSDLEKSQSSDSFSQD 620

Query: 456 DTDNDWPIYVE---SGEENDPAGDDSDD-------KPQIQPN-LSDRETLT 495
            +    P+ V+      EN  A  DS         +  IQP+ +SD+E L+
Sbjct: 621 TSVTLMPVSVKLPVHPVENSVAEFDSHSGGSYCKLRSMIQPHGVSDQEKLS 671



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 1/69 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K H C  C         LK H ++HT ++ + C+ CGK F  Q  L  H +  H   RP 
Sbjct: 477 KPHLCDICGRGFSNFSNLKEHKKTHTADKVFTCDECGKSFNMQRKLVKHRIR-HTGERPY 535

Query: 399 ICKGCRRTF 407
            C  C + F
Sbjct: 536 SCSACGKCF 544



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 1/69 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K + C  C       G ++RHI  H+GE+P+ C+ CG+ F+   +L+ H    H +++  
Sbjct: 449 KPYICEICGKRFAASGDVQRHIIIHSGEKPHLCDICGRGFSNFSNLKEHK-KTHTADKVF 507

Query: 399 ICKGCRRTF 407
            C  C ++F
Sbjct: 508 TCDECGKSF 516



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 8/66 (12%)

Query: 366 ERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFT--SHLSQGLRRFG---- 419
           +R Y CE CGK F    +L  H  S H   +P  C  C + F+   +L   LRR      
Sbjct: 392 QRQYACELCGKPFKHPSNLELHKRS-HTGEKPFECNICGKHFSQAGNLQTHLRRHSGEKP 450

Query: 420 -LCDSC 424
            +C+ C
Sbjct: 451 YICEIC 456


>gi|239753123 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]
          Length = 875

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 41/118 (34%), Positives = 68/118 (57%), Gaps = 4/118 (3%)

Query: 9   KLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASL 68
           ++L ELN+QR+   F D  I+VEGR F+ H+N+L + S YF+ L+   +QDSG+     L
Sbjct: 314 EMLKELNQQRRAKAFTDLKIVVEGREFEVHQNVLASCSLYFKDLIQRSVQDSGQGGREKL 373

Query: 69  DIVTS----DAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSL 122
           ++V S    D   ++L+F+Y+G L +   N   ++ AAS  Q +     C +++   L
Sbjct: 374 ELVLSNLQADVLELLLEFVYTGSLVIDSANAKTLLEAASKFQFHTFCKVCVSFLEKQL 431


>gi|239747686 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]
          Length = 702

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 41/118 (34%), Positives = 68/118 (57%), Gaps = 4/118 (3%)

Query: 9   KLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASL 68
           ++L ELN+QR+   F D  I+VEGR F+ H+N+L + S YF+ L+   +QDSG+     L
Sbjct: 314 EMLKELNQQRRAKAFTDLKIVVEGREFEVHQNVLASCSLYFKDLIQRSVQDSGQGGREKL 373

Query: 69  DIVTS----DAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSL 122
           ++V S    D   ++L+F+Y+G L +   N   ++ AAS  Q +     C +++   L
Sbjct: 374 ELVLSNLQADVLELLLEFVYTGSLVIDSANAKTLLEAASKFQFHTFCKVCVSFLEKQL 431


>gi|239741555 PREDICTED: kelch repeat and BTB (POZ) domain
           containing 9 [Homo sapiens]
          Length = 875

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 41/118 (34%), Positives = 68/118 (57%), Gaps = 4/118 (3%)

Query: 9   KLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASL 68
           ++L ELN+QR+   F D  I+VEGR F+ H+N+L + S YF+ L+   +QDSG+     L
Sbjct: 314 EMLKELNQQRRAKAFTDLKIVVEGREFEVHQNVLASCSLYFKDLIQRSVQDSGQGGREKL 373

Query: 69  DIVTS----DAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSL 122
           ++V S    D   ++L+F+Y+G L +   N   ++ AAS  Q +     C +++   L
Sbjct: 374 ELVLSNLQADVLELLLEFVYTGSLVIDSANAKTLLEAASKFQFHTFCKVCVSFLEKQL 431


>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
          Length = 733

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 46/138 (33%), Positives = 77/138 (55%), Gaps = 18/138 (13%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ME   +  +LL +LN QR + F CD  I+V+  +F+AH+N+L A+S Y ++L++H    +
Sbjct: 24  MEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLN 83

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGE-------------NVIEVMSAASYLQM 107
             H     D+V+   F ++LDF+Y+G+L    E             ++  V++AASYLQ+
Sbjct: 84  LDH-----DMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQI 138

Query: 108 NDVVNFCKTYIRSSLDIC 125
            D+V  CK  ++     C
Sbjct: 139 PDLVALCKKRLKRHGKYC 156



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)

Query: 341 HKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIIC 400
           + C  C     Q+G + RH+RSH G +P+ C+ CG RFTRQ  L  H + +H   +P  C
Sbjct: 535 YPCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEH-MRIHSGEKPYEC 593

Query: 401 KGC------RRTFTSHL 411
           + C      +R   SH+
Sbjct: 594 QVCGGKFAQQRNLISHM 610



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRP 397
           ++ ++C  C  + K    L++H ++H   RPYPC  CGK+FT++  +  H  S H   +P
Sbjct: 504 LRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRS-HLGLKP 562

Query: 398 IICKGCRRTFT 408
             C  C   FT
Sbjct: 563 FACDACGMRFT 573



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 19/50 (38%), Positives = 29/50 (58%)

Query: 338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSH 387
           +K   C  C     ++  L  H+R H+GE+PY C+ CG +F +Q +L SH
Sbjct: 560 LKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISH 609


>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
          Length = 714

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 46/138 (33%), Positives = 77/138 (55%), Gaps = 18/138 (13%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
           ME   +  +LL +LN QR + F CD  I+V+  +F+AH+N+L A+S Y ++L++H    +
Sbjct: 5   MEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLN 64

Query: 61  GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGE-------------NVIEVMSAASYLQM 107
             H     D+V+   F ++LDF+Y+G+L    E             ++  V++AASYLQ+
Sbjct: 65  LDH-----DMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQI 119

Query: 108 NDVVNFCKTYIRSSLDIC 125
            D+V  CK  ++     C
Sbjct: 120 PDLVALCKKRLKRHGKYC 137



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 28/77 (36%), Positives = 41/77 (53%), Gaps = 7/77 (9%)

Query: 341 HKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIIC 400
           + C  C     Q+G + RH+RSH G +P+ C+ CG RFTRQ  L  H + +H   +P  C
Sbjct: 516 YPCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEH-MRIHSGEKPYEC 574

Query: 401 KGC------RRTFTSHL 411
           + C      +R   SH+
Sbjct: 575 QVCGGKFAQQRNLISHM 591



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRP 397
           ++ ++C  C  + K    L++H ++H   RPYPC  CGK+FT++  +  H  S H   +P
Sbjct: 485 LRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRS-HLGLKP 543

Query: 398 IICKGCRRTFT 408
             C  C   FT
Sbjct: 544 FACDACGMRFT 554



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 19/50 (38%), Positives = 29/50 (58%)

Query: 338 IKLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSH 387
           +K   C  C     ++  L  H+R H+GE+PY C+ CG +F +Q +L SH
Sbjct: 541 LKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISH 590


>gi|11968150 GDNF-inducible zinc finger protein 1 [Homo sapiens]
          Length = 711

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 105/512 (20%), Positives = 181/512 (35%), Gaps = 111/512 (21%)

Query: 1   MEMQSYYAKLLGELNEQRKRDFFCDCSIIVE----GRIFKAHRNILFANSGYFRALLIHY 56
           +E +S    LL E++E R     CD ++ VE     + F AH+ +L A S +F+ + ++ 
Sbjct: 8   LESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFFKEVFLNE 67

Query: 57  IQDSGRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFC-- 114
               G  +   L+ V    F+  L+F+Y+ K+ +  + V  ++  A  L+  D+   C  
Sbjct: 68  KSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLDLSETCFQ 127

Query: 115 --KTYIRSSL----DICRKMEKEAAVAAAVAAAAAAAAAAAAAAAH--------QVDSES 160
             K  + S L    +     E E +  + V+AA A  A+ A    H            E 
Sbjct: 128 LKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVATDGPHPSGLTDSLDYPGER 187

Query: 161 PSSG------------------------------REGTSCGTKSLVSSPAEGEKSVECLR 190
            S+G                                G   G K  V  P   +K    LR
Sbjct: 188 ASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPK--KKYTRRLR 245

Query: 191 ESPCGDCGDCHPLELVVRDSLGGGSADSNLSTPPKRIEPKVEFDADEVEVDVGEQLQQYA 250
           E      GD              G         P R+  ++E  +       G +L++ +
Sbjct: 246 EQQKTAEGDV-------------GDYRCPQDQSPDRVGTEMEQVSKNEGCQAGAELEELS 292

Query: 251 APLNLAHVEEALPSGQAVDLAYSNYHVKQFLEALLRNSAAPSKDDADHHFSRSLEGRPEG 310
                   EE     +  +   SN+      +A L   +        H  +  +  R + 
Sbjct: 293 KKAGPEEEEEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDT 352

Query: 311 AGVAMSSMMDVQADWYGEDSGDVLVVPIKLHKCPFCPYTAKQKGILKRHI---------- 360
            G   ++  ++++      S +      +   C  C    K+K  +KRH+          
Sbjct: 353 CGQTFANRCNLKSHQRHVHSSE------RHFPCELCGKKFKRKKDVKRHVLQVHEGGGER 406

Query: 361 --------------------RSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIIC 400
                               R+HTG+RPY C  CG RF++   L++H + +H   +P +C
Sbjct: 407 HRCGQCGKGLSSKTALRLHERTHTGDRPYGCTECGARFSQPSALKTH-MRIHTGEKPFVC 465

Query: 401 KGCRRTFTSH--------LSQGLRRFGLCDSC 424
             C   FT +           G R F +C++C
Sbjct: 466 DECGARFTQNHMLIYHKRCHTGERPF-MCETC 496



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 33/70 (47%), Positives = 42/70 (60%), Gaps = 1/70 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K  KC  C  T  Q+  L +HI+ HTGERPY C+ CGK+FT+   L+ H   +H   RP 
Sbjct: 517 KPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHR-RIHTGERPF 575

Query: 399 ICKGCRRTFT 408
           +C  C RTFT
Sbjct: 576 MCNACGRTFT 585



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 30/70 (42%), Positives = 39/70 (55%), Gaps = 1/70 (1%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKG 402
           C  C     Q  +L  H R HTGERP+ CETCGK F  +E+L+ H   +H  ++P  C+ 
Sbjct: 465 CDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHN-RIHTGSKPFKCEV 523

Query: 403 CRRTFTSHLS 412
           C RTF    S
Sbjct: 524 CFRTFAQRNS 533



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 24/159 (15%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKG 402
           C  C  +   K  LK H R HTG +P+ CE C + F ++  L  H + VH   RP  C  
Sbjct: 493 CETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQH-IKVHTGERPYCCDQ 551

Query: 403 CRRTFTS--------HLSQGLRRFGLCDSC-TCVTDTPDDDDDLMPINLSLVEASSESQE 453
           C + FT          +  G R F +C++C    TD             S +   +   +
Sbjct: 552 CGKQFTQLNALQRHRRIHTGERPF-MCNACGRTFTDK------------STLRRHTSIHD 598

Query: 454 KSDTDNDWPIYVESGEENDPA-GDDSDDKPQIQPNLSDR 491
           K+     + + V+   +ND     +  D+  +   LSD+
Sbjct: 599 KNTPWKSFLVIVDGSPKNDDGHKTEQPDEEYVSSKLSDK 637


>gi|5174473 intracisternal A particle-promoted polypeptide isoform 1
           [Homo sapiens]
          Length = 584

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 40/114 (35%), Positives = 67/114 (58%), Gaps = 1/114 (0%)

Query: 10  LLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASLD 69
           +L ++N+ R    FCD  + V    FKAHR +L A+S YF AL    +++S +     L 
Sbjct: 23  ILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDVVPILG 82

Query: 70  IVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLD 123
           I  +  F I+LDF+Y+G +++   NV E++ AA  LQ+ +VV+ C  +++  +D
Sbjct: 83  I-EAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQID 135


>gi|223890235 intracisternal A particle-promoted polypeptide isoform
           2 [Homo sapiens]
          Length = 582

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 40/114 (35%), Positives = 67/114 (58%), Gaps = 1/114 (0%)

Query: 10  LLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDSGRHSTASLD 69
           +L ++N+ R    FCD  + V    FKAHR +L A+S YF AL    +++S +     L 
Sbjct: 23  ILAQINKMRNGQHFCDVQLQVGQESFKAHRLVLAASSPYFAALFTGGMKESSKDVVPILG 82

Query: 70  IVTSDAFSIILDFLYSGKLDLCGENVIEVMSAASYLQMNDVVNFCKTYIRSSLD 123
           I  +  F I+LDF+Y+G +++   NV E++ AA  LQ+ +VV+ C  +++  +D
Sbjct: 83  I-EAGIFQILLDFIYTGIVNIGVNNVQELIIAADMLQLTEVVHLCCEFLKGQID 135


>gi|58000461 zinc finger protein 648 [Homo sapiens]
          Length = 568

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 31/72 (43%), Positives = 41/72 (56%)

Query: 341 HKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIIC 400
           ++C FC          ++HIR+HTGE+PYPC  CGK F R   LR H  ++H +N+P  C
Sbjct: 307 YQCSFCDKAYTWSSDHRKHIRTHTGEKPYPCPDCGKAFVRSSDLRKHQRNMHSNNKPFPC 366

Query: 401 KGCRRTFTSHLS 412
             C  TF   LS
Sbjct: 367 SECGLTFNKPLS 378



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 31/77 (40%), Positives = 39/77 (50%), Gaps = 3/77 (3%)

Query: 342 KCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICK 401
           KC  C     Q   L RH R HTGERP+PC  CG+ F R   L+ H   +H   +  +C 
Sbjct: 449 KCADCGVAFAQPSRLVRHQRIHTGERPFPCTQCGQAFARSSTLKRHQ-QIHSGEKGFLCA 507

Query: 402 GCRRTF--TSHLSQGLR 416
            C R F   S L+Q +R
Sbjct: 508 ECGRAFRIASELAQHIR 524



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPI 398
           K  +CP C         +  H R H+GERP+PC TCGK FT+  +L  H  ++H   RP 
Sbjct: 390 KPFRCPACDREFAVASRMVEHQRVHSGERPFPCPTCGKCFTKSSNLSEHQ-TLHTGQRPF 448

Query: 399 ICKGCRRTF 407
            C  C   F
Sbjct: 449 KCADCGVAF 457



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 22/45 (48%), Positives = 26/45 (57%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSH 387
           C  C    +    L +HIR H GERPY CE CG+ FTR  HL+ H
Sbjct: 506 CAECGRAFRIASELAQHIRMHNGERPYQCEDCGQAFTRSNHLQRH 550



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 1/65 (1%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKG 402
           CP C     +   L  H   HTG+RP+ C  CG  F +   L  H   +H   RP  C  
Sbjct: 422 CPTCGKCFTKSSNLSEHQTLHTGQRPFKCADCGVAFAQPSRLVRHQ-RIHTGERPFPCTQ 480

Query: 403 CRRTF 407
           C + F
Sbjct: 481 CGQAF 485



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 3/73 (4%)

Query: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRPIICKG 402
           C  C  T  +   L RH R+H G +P+ C  C + F     +  H   VH   RP  C  
Sbjct: 366 CSECGLTFNKPLSLLRHQRTHLGAKPFRCPACDREFAVASRMVEHQ-RVHSGERPFPCPT 424

Query: 403 CRRTFT--SHLSQ 413
           C + FT  S+LS+
Sbjct: 425 CGKCFTKSSNLSE 437



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 2/70 (2%)

Query: 339 KLHKCPFCPYTAKQKGILKRHIRS-HTGERPYPCETCGKRFTRQEHLRSHALSVHRSNRP 397
           K + CP C     +   L++H R+ H+  +P+PC  CG  F +   L  H    H   +P
Sbjct: 333 KPYPCPDCGKAFVRSSDLRKHQRNMHSNNKPFPCSECGLTFNKPLSLLRHQ-RTHLGAKP 391

Query: 398 IICKGCRRTF 407
             C  C R F
Sbjct: 392 FRCPACDREF 401


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,868,443
Number of Sequences: 37866
Number of extensions: 956254
Number of successful extensions: 21570
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1187
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 6332
Number of HSP's gapped (non-prelim): 11341
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.