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Search of human proteins with 224589138
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224589138 patatin-like phospholipase domain containing 1
isoform 2 [Homo sapiens]
(446 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224589138 patatin-like phospholipase domain containing 1 isof... 915 0.0
gi|238776840 patatin-like phospholipase domain containing 1 isof... 887 0.0
gi|224593249 patatin-like phospholipase domain containing 1 isof... 887 0.0
gi|32698724 patatin-like phospholipase domain containing 2 [Homo... 167 2e-41
gi|17196626 patatin-like phospholipase domain containing 3 [Homo... 132 6e-31
gi|20304127 patatin-like phospholipase domain containing 5 [Homo... 128 9e-30
gi|215422355 patatin-like phospholipase domain containing 4 [Hom... 102 7e-22
gi|42415471 patatin-like phospholipase domain containing 4 [Homo... 102 7e-22
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 3e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 1e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 62 1e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 58 2e-08
gi|117938768 GNAS complex locus alex [Homo sapiens] 57 3e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 55 1e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 55 1e-07
gi|71274152 hypothetical protein LOC388939 [Homo sapiens] 55 1e-07
gi|55750053 atrophin-1 [Homo sapiens] 54 4e-07
gi|55750041 atrophin-1 [Homo sapiens] 54 4e-07
gi|146134388 YLP motif containing 1 [Homo sapiens] 54 4e-07
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 53 6e-07
gi|57863314 vacuolar protein sorting 37C [Homo sapiens] 52 1e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 52 1e-06
gi|50345997 E1A binding protein p300 [Homo sapiens] 51 2e-06
gi|52630419 sterol regulatory element binding transcription fact... 51 2e-06
gi|22547195 sterol regulatory element binding transcription fact... 51 2e-06
gi|11386183 WAS protein family, member 2 [Homo sapiens] 51 2e-06
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 51 2e-06
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 51 2e-06
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 51 2e-06
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 50 3e-06
>gi|224589138 patatin-like phospholipase domain containing 1 isoform
2 [Homo sapiens]
Length = 446
Score = 915 bits (2366), Expect = 0.0
Identities = 446/446 (100%), Positives = 446/446 (100%)
Query: 1 MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP 60
MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP
Sbjct: 1 MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP 60
Query: 61 VYCGLIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA 120
VYCGLIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA
Sbjct: 61 VYCGLIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA 120
Query: 121 IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSS 180
IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSS
Sbjct: 121 IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSS 180
Query: 181 SKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP 240
SKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP
Sbjct: 181 SKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP 240
Query: 241 PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPG 300
PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPG
Sbjct: 241 PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPG 300
Query: 301 SSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAF 360
SSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAF
Sbjct: 301 SSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAF 360
Query: 361 PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKK 420
PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKK
Sbjct: 361 PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKK 420
Query: 421 NKQKTSGTRKGFPRHSGSKKPSSKVQ 446
NKQKTSGTRKGFPRHSGSKKPSSKVQ
Sbjct: 421 NKQKTSGTRKGFPRHSGSKKPSSKVQ 446
>gi|238776840 patatin-like phospholipase domain containing 1 isoform
3 [Homo sapiens]
Length = 532
Score = 887 bits (2293), Expect = 0.0
Identities = 437/446 (97%), Positives = 437/446 (97%), Gaps = 9/446 (2%)
Query: 1 MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP 60
MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP
Sbjct: 96 MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP 155
Query: 61 VYCGLIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA 120
VYCGLIPPTYRGV RYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA
Sbjct: 156 VYCGLIPPTYRGV---------RYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA 206
Query: 121 IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSS 180
IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSS
Sbjct: 207 IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSS 266
Query: 181 SKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP 240
SKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP
Sbjct: 267 SKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP 326
Query: 241 PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPG 300
PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPG
Sbjct: 327 PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPG 386
Query: 301 SSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAF 360
SSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAF
Sbjct: 387 SSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAF 446
Query: 361 PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKK 420
PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKK
Sbjct: 447 PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKK 506
Query: 421 NKQKTSGTRKGFPRHSGSKKPSSKVQ 446
NKQKTSGTRKGFPRHSGSKKPSSKVQ
Sbjct: 507 NKQKTSGTRKGFPRHSGSKKPSSKVQ 532
>gi|224593249 patatin-like phospholipase domain containing 1 isoform
1 [Homo sapiens]
Length = 437
Score = 887 bits (2293), Expect = 0.0
Identities = 437/446 (97%), Positives = 437/446 (97%), Gaps = 9/446 (2%)
Query: 1 MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP 60
MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP
Sbjct: 1 MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP 60
Query: 61 VYCGLIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA 120
VYCGLIPPTYRGV RYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA
Sbjct: 61 VYCGLIPPTYRGV---------RYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA 111
Query: 121 IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSS 180
IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSS
Sbjct: 112 IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLNAVYLNSS 171
Query: 181 SKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP 240
SKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP
Sbjct: 172 SKRVIFPRVEVYCQIELALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP 231
Query: 241 PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPG 300
PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPG
Sbjct: 232 PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPG 291
Query: 301 SSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAF 360
SSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAF
Sbjct: 292 SSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAF 351
Query: 361 PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKK 420
PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKK
Sbjct: 352 PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKK 411
Query: 421 NKQKTSGTRKGFPRHSGSKKPSSKVQ 446
NKQKTSGTRKGFPRHSGSKKPSSKVQ
Sbjct: 412 NKQKTSGTRKGFPRHSGSKKPSSKVQ 437
>gi|32698724 patatin-like phospholipase domain containing 2 [Homo
sapiens]
Length = 504
Score = 167 bits (422), Expect = 2e-41
Identities = 79/171 (46%), Positives = 118/171 (69%), Gaps = 9/171 (5%)
Query: 1 MVQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVP 60
+V+++R FL +VLP DS++ +G+L +SLTR++DGENV++S F SK+ELI+A CS F+P
Sbjct: 90 LVKIIRSFLLKVLPADSHEHASGRLGISLTRVSDGENVIISHFNSKDELIQANVCSGFIP 149
Query: 61 VYCGLIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPA 120
VYCGLIPP+ +GV RY+DGG + P + IT+S FSG+ DICP+D
Sbjct: 150 VYCGLIPPSLQGV---------RYVDGGISDNLPLYELKNTITVSPFSGESDICPQDSST 200
Query: 121 IFHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRR 171
H+ R+ N S QF+L N+ R++ ALFPP+ ++L + +GY D + +L+R
Sbjct: 201 NIHELRVTNTSIQFNLRNLYRLSKALFPPEPLVLREMCKQGYRDGLRFLQR 251
>gi|17196626 patatin-like phospholipase domain containing 3 [Homo
sapiens]
Length = 481
Score = 132 bits (332), Expect = 6e-31
Identities = 68/167 (40%), Positives = 102/167 (61%), Gaps = 9/167 (5%)
Query: 3 QMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVPVY 62
+ +RQ L + LP + +++ +GK+ +SLTR++DGENV+VS+F SK+E+++AL CSCF+P Y
Sbjct: 92 KFLRQGLCKCLPANVHQLISGKIGISLTRVSDGENVLVSDFRSKDEVVDALVCSCFIPFY 151
Query: 63 CGLIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPAIF 122
GLIPP++RGV RY+DGG + P IT+S F G+ DICP+ F
Sbjct: 152 SGLIPPSFRGV---------RYVDGGVSDNVPFIDAKTTITVSPFYGEYDICPKVKSTNF 202
Query: 123 HDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYL 169
+ S + N+ ++ A PPDL +L + RGY DA +L
Sbjct: 203 LHVDITKLSLRLCTGNLYLLSRAFVPPDLKVLGEICLRGYLDAFRFL 249
>gi|20304127 patatin-like phospholipase domain containing 5 [Homo
sapiens]
Length = 429
Score = 128 bits (322), Expect = 9e-30
Identities = 67/170 (39%), Positives = 97/170 (57%), Gaps = 9/170 (5%)
Query: 2 VQMMRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVPV 61
++ ++Q L LP D++ + + +L +SLTR DG N +V++F + +ELI+AL C+ + P
Sbjct: 93 IEHVKQQLQDALPPDAHVLASQRLGISLTRWPDGRNFLVTDFATCDELIQALVCTLYFPF 152
Query: 62 YCGLIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPAI 121
YCGLIPP +RG +RYIDG + P A IT+S F G DICP+
Sbjct: 153 YCGLIPPEFRG---------ERYIDGALSNNLPFADCPSTITVSPFHGTVDICPQSTSPN 203
Query: 122 FHDFRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRR 171
H+ +FN SFQ S EN L PP L ++ D +GY DA+ +L R
Sbjct: 204 LHELNVFNFSFQISTENFFLGLICLIPPSLEVVADNCRQGYLDALRFLER 253
>gi|215422355 patatin-like phospholipase domain containing 4 [Homo
sapiens]
Length = 253
Score = 102 bits (254), Expect = 7e-22
Identities = 58/169 (34%), Positives = 89/169 (52%), Gaps = 9/169 (5%)
Query: 5 MRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVPVYCG 64
+R + +LP ++++ +LHVS+T EN +VS F+S+E+LI+ L S FVP+Y G
Sbjct: 91 LRSGMESILPPSAHELAQNRLHVSITNAKTRENHLVSTFSSREDLIKVLLASSFVPIYAG 150
Query: 65 LIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPAIFHD 124
L Y+G Q+++DGG T P +TIS FSG+ DI P+D +
Sbjct: 151 LKLVEYKG---------QKWVDGGLTNALPILPVGRTVTISPFSGRLDISPQDKGQLDLY 201
Query: 125 FRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLN 173
+ SL N+ R+ ALFPP + Y G++D V +L + N
Sbjct: 202 VNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVKFLLKEN 250
>gi|42415471 patatin-like phospholipase domain containing 4 [Homo
sapiens]
Length = 253
Score = 102 bits (254), Expect = 7e-22
Identities = 58/169 (34%), Positives = 89/169 (52%), Gaps = 9/169 (5%)
Query: 5 MRQFLYRVLPEDSYKVTTGKLHVSLTRLTDGENVVVSEFTSKEELIEALYCSCFVPVYCG 64
+R + +LP ++++ +LHVS+T EN +VS F+S+E+LI+ L S FVP+Y G
Sbjct: 91 LRSGMESILPPSAHELAQNRLHVSITNAKTRENHLVSTFSSREDLIKVLLASSFVPIYAG 150
Query: 65 LIPPTYRGVWAFLTLPPQRYIDGGFTGMQPCAFWTDAITISTFSGQQDICPRDCPAIFHD 124
L Y+G Q+++DGG T P +TIS FSG+ DI P+D +
Sbjct: 151 LKLVEYKG---------QKWVDGGLTNALPILPVGRTVTISPFSGRLDISPQDKGQLDLY 201
Query: 125 FRMFNCSFQFSLENIARMTHALFPPDLVILHDYYYRGYEDAVLYLRRLN 173
+ SL N+ R+ ALFPP + Y G++D V +L + N
Sbjct: 202 VNIAKQDIMLSLANLVRLNQALFPPSKRKMESLYQCGFDDTVKFLLKEN 250
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/114 (40%), Positives = 57/114 (50%), Gaps = 8/114 (7%)
Query: 256 PVSAPVSPLEQPPAQ--PLASSTPLSLSGMPPVSFP--AVHKPPSSTPGSSLPTPPPGLS 311
P S P+SPL +PP Q P ++ PL PP SFP A P +S P S L TPPP
Sbjct: 773 PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832
Query: 312 PLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPP 365
P+ +Q SP S QAP P P+ GP T + PR +L+ P PP
Sbjct: 833 PVLAAPLLQVPPSPPASPTLQAPRRP-PTPGPDT---SVSGPRLTLALAPGPPP 882
Score = 62.8 bits (151), Expect = 6e-10
Identities = 57/191 (29%), Positives = 74/191 (38%), Gaps = 29/191 (15%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPS--- 296
P + P Q P+ P SP PP P A+ P PP++ P + PPS
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQVPPSPPA 743
Query: 297 STPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAP-QTLPRS 355
S P S TPPP + PL +Q SP SL P P P+ P Q LP S
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP-S 802
Query: 356 SLSAFPAQP--------PVEELGQEQPQAVALLVSSKPKSAVPLVHV------KETVSKP 401
++FP Q P+ L PQA P A PL+ V T+ P
Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQA-------PPVLAAPLLQVPPSPPASPTLQAP 855
Query: 402 YVTESPAEDSN 412
+P D++
Sbjct: 856 RRPPTPGPDTS 866
Score = 55.8 bits (133), Expect = 8e-08
Identities = 66/224 (29%), Positives = 80/224 (35%), Gaps = 27/224 (12%)
Query: 204 PERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPP---VSQPVQTLEFTCESPVSAP 260
P + P L+ A L T PH E P PP + P +T P AP
Sbjct: 539 PSLAPPPLQTASAPL---TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595
Query: 261 ---VSP----LEQPPAQPLASSTPLS--LSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLS 311
SP L PP PLA+ P + +PP+ P PP+S P S L TP P
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP--SPPASPPLSPLATPSPQAP 653
Query: 312 PLSPQQQVQPSGSPARSLHSQAPTSP--RPSLGPSTVGAPQTLPRSSLSAF------PAQ 363
+Q SP S QAP SP P + PS Q P + PA
Sbjct: 654 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 713
Query: 364 PPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESP 407
PP+ PQA L + P VP P T P
Sbjct: 714 PPMSPSATPPPQAPPPLAA--PPLQVPPSPPASPPMSPSATPPP 755
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/198 (28%), Positives = 73/198 (36%), Gaps = 36/198 (18%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPP-------AQPLASSTPLSLSGMPPVSFPAVH 292
P P+Q L AP+S L PP A P + P SL+ P + P++
Sbjct: 483 PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542
Query: 293 KPPSSTPGSSLPTP----PPGLSPLSPQQQVQPSGSPARSLHS-------QAPTS----- 336
PP T + L TP PP +P Q P +P S QAP +
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPP 602
Query: 337 ----PRPSLGPSTVGAPQTLPRSSLSAF------PAQPPVEELGQEQPQ---AVALLVSS 383
P P L P PQ P +L PA PP+ L PQ A+A+ +
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 662
Query: 384 KPKSAVPLVHVKETVSKP 401
P S P V+ S P
Sbjct: 663 APFSPPPSPPVQAPFSPP 680
Score = 54.3 bits (129), Expect = 2e-07
Identities = 52/172 (30%), Positives = 68/172 (39%), Gaps = 27/172 (15%)
Query: 240 PPVSQPVQTLEFTC-ESP-------VSAPVSPLEQPPAQPLASSTPLSLSGMPPVS---F 288
PP S P+ L ++P + AP SP PP Q P S PPVS
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-----APFSPPASPPVSPSAT 690
Query: 289 PAVHKPPS-STPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHS-QAPTSP--RPSLGPS 344
P PPS + P +P PP P+SP P P + Q P SP P + PS
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750
Query: 345 TVGAPQTLPRSSLSAF------PAQPPVEELGQEQPQAVALLVSSKPKSAVP 390
P+ P + PA P+ L + PQA L ++ P A+P
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL-ATPPLQALP 801
Score = 50.8 bits (120), Expect = 2e-06
Identities = 63/239 (26%), Positives = 90/239 (37%), Gaps = 62/239 (25%)
Query: 210 SLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPA 269
S R QASL ++P + PP S P+Q +P+S P SP Q
Sbjct: 433 SPRQTQASLTSPSRP------------ASTPPDSPPLQ-------APLSLPASPPLQTSL 473
Query: 270 QPLAS--STPLSLSGMPPVSFPAVHKPPS---------------------STPGSSLPTP 306
P S S+PL++ + +S A H P + TP +SL TP
Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533
Query: 307 P----PGLSP----------LSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTL 352
P P L+P +P + P +P +P + P PS++ P
Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 353 PRSSLSAFPAQ----PPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESP 407
+L++ P Q PP+ L PQA L + P A P +S P T SP
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXL-ALPPLQAPPSPPASPPLS-PLATPSP 650
Score = 43.1 bits (100), Expect = 5e-04
Identities = 55/203 (27%), Positives = 83/203 (40%), Gaps = 43/203 (21%)
Query: 240 PPVSQPVQTLEFTCESPVSAPV--SPLEQPPAQPLASST------PLSLSGMPPVSFPAV 291
PP++ P+ + +P S SP PP+Q S T P SL +PP+
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI----- 389
Query: 292 HKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPA-RSLHSQAPTSPR--------PSLG 342
+ P S SL PP L+ LS Q GSP ++ HS SPR PS
Sbjct: 390 -QVPHSLTSPSLQAPPSPLA-LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447
Query: 343 PSTVGAPQTLPRSSLSAFPAQPPVE------------ELGQEQPQAVALLVSSKPKS--- 387
ST P + P + + PA PP++ L QA++ L S P++
Sbjct: 448 AST--PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505
Query: 388 --AVPLVHVKETVSKPYVTESPA 408
+P + + +++ P + PA
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPA 528
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/192 (28%), Positives = 71/192 (36%), Gaps = 36/192 (18%)
Query: 204 PERSQPSLRARQASLEGATQPHKEWV----------PKGDGRGSHGPPVSQPVQTLEFTC 253
P RS PS R + +QP + + P+ D + GP S P+ T
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT----- 306
Query: 254 ESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPL 313
SP P+ PP A+ P +L PPS + LP PP SP
Sbjct: 307 PSPSGTKARPV--PPPDNAATPLPATL-------------PPSPPLATPLPLAPP--SPS 349
Query: 314 SPQQQVQPSGSPARSLHSQAP---TSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELG 370
+P +Q SP + SQAP T+P PS P SL++ Q P L
Sbjct: 350 AP-PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA 408
Query: 371 QEQPQAVALLVS 382
QA L S
Sbjct: 409 LSSLQATTSLGS 420
Score = 34.7 bits (78), Expect = 0.18
Identities = 39/137 (28%), Positives = 50/137 (36%), Gaps = 25/137 (18%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTP 299
PP + PV + P S P SP Q P +P S+SG P ++ PP
Sbjct: 828 PPQAPPVLAAPLL-QVPPSPPASPTLQAPRRPPTPGPDTSVSG-PRLTLALAPGPP---- 881
Query: 300 GSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSA 359
PPP SP S P + HS + TS P + + P +A
Sbjct: 882 ------PPPSRSPSS------TLSGPDLAGHSSSATST-----PEELRGYDSGPEGGAAA 924
Query: 360 FPAQPPVEELGQEQPQA 376
P PP EL P A
Sbjct: 925 SP--PPDAELAACHPAA 939
Score = 30.4 bits (67), Expect = 3.4
Identities = 44/190 (23%), Positives = 72/190 (37%), Gaps = 29/190 (15%)
Query: 260 PVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQV 319
P SP PP P A L V + + G+++P P P
Sbjct: 30 PGSPRPPPPVTPAALRV---LGAAGAVGRKPLAERAGGIGGATIPESAPRAGP------T 80
Query: 320 QPSGSPARSLHSQAPTSPRPSLGP---STVGAPQTLP-RSSLSAFPAQPPVEELG----Q 371
+ +G+ +R+ S+ P S R P +T P + P R+S + P P+ + G
Sbjct: 81 RSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PLGQKGLRISA 138
Query: 372 EQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKKNKQKTSGTRKG 431
E+ A + +SA+ ++T T SPA + + +GT G
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA----------MARRSRAAGTEVG 188
Query: 432 FPRHSGSKKP 441
PR + S +P
Sbjct: 189 LPRPAPSARP 198
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 61.6 bits (148), Expect = 1e-09
Identities = 54/175 (30%), Positives = 70/175 (40%), Gaps = 22/175 (12%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQ--PLASSTPLSLSGMPPVSFPAVHK---- 293
PP S PVQ P S PVSP PP+Q P ++ PL + PP S P
Sbjct: 442 PPPSPPVQA---PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 498
Query: 294 ----PPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAP 349
PP + P L PPP P +Q SP S QAP SP SL S + P
Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
Query: 350 QTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVT 404
L+A P+ ++ P + L +P + P +VS P +T
Sbjct: 559 PPQAPPVLAA-----PLLQVPPSPPASPTLQAPRRPPTPGP----DTSVSGPRLT 604
Score = 56.2 bits (134), Expect = 6e-08
Identities = 61/215 (28%), Positives = 87/215 (40%), Gaps = 28/215 (13%)
Query: 204 PERSQPSLRARQASLEGATQPHKEWV----------PKGDGRGSHGPPVSQPVQTLEFTC 253
P RS PS R + +QP + + P+ D + GP S P+ T +
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 311
Query: 254 ESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPL 313
AP + PA P +SS L+ P++ P+ PPS +LP+PP
Sbjct: 312 ALQSQAPPTL----PATPHSSSLTCQLATPLPLAPPSPSAPPSL---QTLPSPPA----T 360
Query: 314 SPQQQVQPSGSPA-RSLHSQAPTSPRPSLGPSTVGAPQTL---PRSSLSAFPAQPPVEEL 369
P Q GSP ++ HS P+ P L AP L P + + PA PP+ L
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
Query: 370 GQEQPQ---AVALLVSSKPKSAVPLVHVKETVSKP 401
PQ A+A+ + P S P V+ S P
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 455
Score = 56.2 bits (134), Expect = 6e-08
Identities = 51/184 (27%), Positives = 71/184 (38%), Gaps = 12/184 (6%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLS--LSGMPPVSFPAVHKPPSS 297
PP + P Q + A S L PP PLA+ P + +PP+ P PP+S
Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP--SPPAS 414
Query: 298 TPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSP--RPSLGPSTVGAPQTLPRS 355
P S L TP P +Q SP S QAP SP P + PS Q P
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 474
Query: 356 SLSAF------PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAE 409
+ PA PP+ PQA L + + A P ++ P + P+
Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 534
Query: 410 DSNW 413
+++
Sbjct: 535 PASF 538
Score = 36.6 bits (83), Expect = 0.047
Identities = 53/211 (25%), Positives = 79/211 (37%), Gaps = 45/211 (21%)
Query: 204 PERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQP-VQTLEFTCESPVSAPVS 262
P ++ PSL A + + P PP++ P +Q + ++P +
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526
Query: 263 PLEQPPAQPLA----------SSTPLS-LSGMPPVSFPAVHKP----PSSTPGSSL---- 303
PL+ P+ P + +S P+S L+ PP + P + P P S P S
Sbjct: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586
Query: 304 ---PTPPPGLS--------PLSPQQQVQPSGSPARSL-------HSQAPTSPRPSLGPST 345
PTP P S L+P PS SP+ +L HS + TS P
Sbjct: 587 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST-----PEE 641
Query: 346 VGAPQTLPRSSLSAFPAQPPVEELGQEQPQA 376
+ + P +A P PP EL P A
Sbjct: 642 LRGYDSGPEGGAAASP--PPDAELAACHPAA 670
Score = 30.4 bits (67), Expect = 3.4
Identities = 44/190 (23%), Positives = 72/190 (37%), Gaps = 29/190 (15%)
Query: 260 PVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQV 319
P SP PP P A L V + + G+++P P P
Sbjct: 30 PGSPRPPPPVTPAALRV---LGAAGAVGRKPLAERAGGIGGATIPESAPRAGP------T 80
Query: 320 QPSGSPARSLHSQAPTSPRPSLGP---STVGAPQTLP-RSSLSAFPAQPPVEELG----Q 371
+ +G+ +R+ S+ P S R P +T P + P R+S + P P+ + G
Sbjct: 81 RSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PLGQKGLRISA 138
Query: 372 EQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKKNKQKTSGTRKG 431
E+ A + +SA+ ++T T SPA + + +GT G
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA----------MARRSRAAGTEVG 188
Query: 432 FPRHSGSKKP 441
PR + S +P
Sbjct: 189 LPRPAPSARP 198
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 61.6 bits (148), Expect = 1e-09
Identities = 54/175 (30%), Positives = 70/175 (40%), Gaps = 22/175 (12%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQ--PLASSTPLSLSGMPPVSFPAVHK---- 293
PP S PVQ P S PVSP PP+Q P ++ PL + PP S P
Sbjct: 403 PPPSPPVQA---PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 459
Query: 294 ----PPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAP 349
PP + P L PPP P +Q SP S QAP SP SL S + P
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519
Query: 350 QTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVT 404
L+A P+ ++ P + L +P + P +VS P +T
Sbjct: 520 PPQAPPVLAA-----PLLQVPPSPPASPTLQAPRRPPTPGP----DTSVSGPRLT 565
Score = 56.2 bits (134), Expect = 6e-08
Identities = 51/184 (27%), Positives = 71/184 (38%), Gaps = 12/184 (6%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLS--LSGMPPVSFPAVHKPPSS 297
PP + P Q + A S L PP PLA+ P + +PP+ P PP+S
Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP--SPPAS 375
Query: 298 TPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSP--RPSLGPSTVGAPQTLPRS 355
P S L TP P +Q SP S QAP SP P + PS Q P
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435
Query: 356 SLSAF------PAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAE 409
+ PA PP+ PQA L + + A P ++ P + P+
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495
Query: 410 DSNW 413
+++
Sbjct: 496 PASF 499
Score = 53.1 bits (126), Expect = 5e-07
Identities = 62/224 (27%), Positives = 82/224 (36%), Gaps = 26/224 (11%)
Query: 204 PERSQPSLRARQASLEGATQPHKEWV----------PKGDGRGSHGPPVSQPVQTLEFTC 253
P RS PS R + +QP + + P+ D + GP S P+ T +
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302
Query: 254 ESPVSAPVS--PLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPP--- 308
SAP S L PPA P + +T + + + A H S P S L TPPP
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQAT----TSLGSPTLQATHSFLPSPPLSPLATPPPQAP 358
Query: 309 ---GLSPLS--PQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQ 363
L PL P P SP + QAP + L + P + P + + PA
Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418
Query: 364 PPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESP 407
PPV QA L + P VP P T P
Sbjct: 419 PPVSPSATPPSQAPPSLAA--PPLQVPPSPPASPPMSPSATPPP 460
Score = 36.6 bits (83), Expect = 0.047
Identities = 53/211 (25%), Positives = 79/211 (37%), Gaps = 45/211 (21%)
Query: 204 PERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQP-VQTLEFTCESPVSAPVS 262
P ++ PSL A + + P PP++ P +Q + ++P +
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487
Query: 263 PLEQPPAQPLA----------SSTPLS-LSGMPPVSFPAVHKP----PSSTPGSSL---- 303
PL+ P+ P + +S P+S L+ PP + P + P P S P S
Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 547
Query: 304 ---PTPPPGLS--------PLSPQQQVQPSGSPARSL-------HSQAPTSPRPSLGPST 345
PTP P S L+P PS SP+ +L HS + TS P
Sbjct: 548 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST-----PEE 602
Query: 346 VGAPQTLPRSSLSAFPAQPPVEELGQEQPQA 376
+ + P +A P PP EL P A
Sbjct: 603 LRGYDSGPEGGAAASP--PPDAELAACHPAA 631
Score = 29.6 bits (65), Expect = 5.8
Identities = 40/180 (22%), Positives = 67/180 (37%), Gaps = 31/180 (17%)
Query: 290 AVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRP-SLGPSTVGA 348
A P + PG P PP P P A + P + R +G +T+
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI-- 70
Query: 349 PQTLPRSSLSAFPAQPPVEELGQEQPQAVALL---VSSKPKSA-----VPL------VHV 394
P++ PR+ + ++PP G+ P A VSS +++ PL +
Sbjct: 71 PESAPRAGPTR-TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129
Query: 395 KETVSKPYVTESPAED-------------SNWVNKVFKKNKQKTSGTRKGFPRHSGSKKP 441
+ETV++ TE+P + + + +GT G PR + S +P
Sbjct: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 58.2 bits (139), Expect = 2e-08
Identities = 47/151 (31%), Positives = 63/151 (41%), Gaps = 13/151 (8%)
Query: 240 PPVSQPVQTLEFTCESPVS----APVSPLEQPPAQPLASSTPLSLS-GMPPVSFPAVHKP 294
PP S P LE ESP+S +P SP + P P ++PLS P+S P P
Sbjct: 506 PPESSPFSPLE---ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP 562
Query: 295 PSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLH-----SQAPTSPRPSLGPSTVGAP 349
S P +S +PPP SP+SP + P P + ++P SP P P +
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622
Query: 350 QTLPRSSLSAFPAQPPVEELGQEQPQAVALL 380
+ P PP EE P V+ L
Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653
Score = 55.1 bits (131), Expect = 1e-07
Identities = 46/163 (28%), Positives = 63/163 (38%), Gaps = 16/163 (9%)
Query: 254 ESPVSAPV--SPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLP-----TP 306
ESP+S P SPL PP S P PP + PP + S LP +P
Sbjct: 605 ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP 664
Query: 307 PPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPV 366
PP SPLSP + P+ P + P P+ P P SL + P +
Sbjct: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724
Query: 367 EELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAE 409
E+PQ P+S P H+ +P+++ P E
Sbjct: 725 LLPLPEEPQLC-------PRSEGP--HLSPRPEEPHLSPRPEE 758
Score = 53.1 bits (126), Expect = 5e-07
Identities = 51/168 (30%), Positives = 70/168 (41%), Gaps = 22/168 (13%)
Query: 231 KGDGRGSHGPPVSQPVQTLEFTCES-PVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFP 289
+G +G H + QP + CE+ P+ LE PL PL +PP
Sbjct: 393 QGQPKGGHVTSM-QPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPL----LPPPEES 447
Query: 290 AVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLH-----SQAPTSPRPSLGPS 344
+ PP +P S PPP S LSP + P+ +LH ++P SP P P
Sbjct: 448 PLSPPPEESPTS----PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503
Query: 345 TVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVS-SKPKSAVPL 391
+ P++ P S L P PP +E P + AL S P A PL
Sbjct: 504 S-PPPESSPFSPLEESPLSPP-----EESPPSPALETPLSPPPEASPL 545
Score = 46.6 bits (109), Expect = 5e-05
Identities = 42/157 (26%), Positives = 60/157 (38%), Gaps = 18/157 (11%)
Query: 254 ESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPL 313
ESP+S P P E P + P +S P+S P P S P +S +PPP SP+
Sbjct: 578 ESPMSPP--PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM 635
Query: 314 SPQQQVQPSGSPARSLH--------------SQAPTSPRPSLGPSTVGAPQTLPRSSLSA 359
SP + P P ++P SP P P++ +
Sbjct: 636 SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPED 695
Query: 360 FPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKE 396
P PP E+ P +L+ S P PL+ + E
Sbjct: 696 SPTSPPPEDSPASPPPEDSLM--SLPLEESPLLPLPE 730
Score = 45.8 bits (107), Expect = 8e-05
Identities = 61/215 (28%), Positives = 73/215 (33%), Gaps = 39/215 (18%)
Query: 204 PERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSP 263
PE S PS +LE P E P+S P + ESP+S P
Sbjct: 523 PEESPPS-----PALETPLSPPPE-----------ASPLSPPFE------ESPLSPPPEE 560
Query: 264 LE-QPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPS 322
L PP + S P S M P P P S P +S PP SPLSP + P
Sbjct: 561 LPTSPPPEASRLSPPPEESPMSP---PPEESPMSPPPEASRLFPPFEESPLSPPPEESPL 617
Query: 323 GSPARSLHSQAPTSPRPSLGPSTVGAPQTLPR--SSLSAFPA----QPPVEELGQEQPQA 376
P + P P + P +P + P S LS P PP EE P
Sbjct: 618 SPPPEASRLSPPPEDSP-MSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPP- 675
Query: 377 VALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDS 411
P S P + T P EDS
Sbjct: 676 -----EESPTSPPPEASRLSPPPEDSPTSPPPEDS 705
Score = 44.7 bits (104), Expect = 2e-04
Identities = 43/138 (31%), Positives = 55/138 (39%), Gaps = 20/138 (14%)
Query: 263 PLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTP------PPGLSPLSPQ 316
P E PPAQ LA S P P S+ + P TP P P PP P P
Sbjct: 2349 PQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPF 2408
Query: 317 QQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPR----SSLSAFPAQP-------P 365
+V SP SQ+P +PRP + +P T PR S P++P P
Sbjct: 2409 SRV--PASPQSQSSSQSPLTPRPLSAEAFCPSPVT-PRFQSPDPYSRPPSRPQSRDPFAP 2465
Query: 366 VEELGQEQPQAVALLVSS 383
+ + + QP VA S
Sbjct: 2466 LHKPPRPQPPEVAFKAGS 2483
Score = 43.1 bits (100), Expect = 5e-04
Identities = 63/216 (29%), Positives = 83/216 (38%), Gaps = 36/216 (16%)
Query: 204 PERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHG----PPVSQPVQTLEFTCESPVSA 259
P P L+ R SL+ P V G G+ S PP + + LE E
Sbjct: 2238 PSTPDPFLKPRCPSLDNLAVPESPGV--GGGKASEPLLSPPPFGESRKALEVKKEE---- 2291
Query: 260 PVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTP--GSSLPTPPPGLSPLSPQ- 316
L +S+P G P + F V P S T G L TP +PL+P+
Sbjct: 2292 ------------LGASSPSY--GPPNLGF--VDSPSSGTHLGGLELKTPDVFKAPLTPRA 2335
Query: 317 QQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQP-- 374
QV+P SP L Q P P +L PS P S + AQPP+ Q P
Sbjct: 2336 SQVEPQ-SPGLGLRPQEP-PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPE 2393
Query: 375 QAVAL---LVSSKPKSAVPLVHVKETVSKPYVTESP 407
AL + S P S VP ++ S+ +T P
Sbjct: 2394 SCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP 2429
Score = 40.0 bits (92), Expect = 0.004
Identities = 46/145 (31%), Positives = 57/145 (39%), Gaps = 15/145 (10%)
Query: 241 PVSQPVQTLEFTCESPVSAPVSPL-EQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTP 299
P PV P + +SP E+P P + LS P P KPP P
Sbjct: 813 PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE-P 871
Query: 300 G-----SSLPT-PPPG---LSPLSPQQQVQPSGSPARS-LHSQAPTSP--RPSLGPSTVG 347
G LP PPPG LSPL + + G P S L + P SP PSL P +
Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP 931
Query: 348 A-PQTLPRSSLSAFPAQPPVEELGQ 371
P P S + A P + LG+
Sbjct: 932 PDPLPPPLSPIITAAAPPALSPLGE 956
Score = 37.0 bits (84), Expect = 0.036
Identities = 50/193 (25%), Positives = 70/193 (36%), Gaps = 33/193 (17%)
Query: 241 PVSQPVQTLEFTCESPVSAPVSPLEQ-----PPAQPLASSTPLSLSGMPPVSFPAVHKPP 295
P S P + + P +P SP + PP + S PL S + P+ P
Sbjct: 679 PTSPPPEASRLS-PPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR 737
Query: 296 SSTPGSSLPTPPPGLSP------LSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVG-- 347
S P S P LSP LSPQ + +P SP P L P G
Sbjct: 738 SEGPHLSPRPEEPHLSPRPEEPHLSPQAE-EPHLSPQPEEPCLCAVPEEPHLSPQAEGPH 796
Query: 348 ----------APQTLPRSSLSAFPAQP---PVEELGQEQPQAVALLVSSKPKSAVPLVHV 394
+PQT LS P +P P E PQ+ +S +P+ + H+
Sbjct: 797 LSPQPEELHLSPQT-EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEES----HL 851
Query: 395 KETVSKPYVTESP 407
+ KP ++ P
Sbjct: 852 SPELEKPPLSPRP 864
Score = 37.0 bits (84), Expect = 0.036
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 6/81 (7%)
Query: 233 DGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLAS---STPLSLSGMPPVSFP 289
D R PP +P SP S P PL + P +PLA +PL L+ P + P
Sbjct: 4902 DVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARP 4961
Query: 290 AVHKPPSSTPGSSLPTPPPGL 310
KP + P + PP L
Sbjct: 4962 ---KPRARPPEEGEDSRPPRL 4979
Score = 35.0 bits (79), Expect = 0.14
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 27/146 (18%)
Query: 241 PVSQPVQTLE-FTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTP 299
P P L+ F+ +AP+ ++ P +QP TP SL+ S
Sbjct: 1104 PAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLA--------------SELK 1149
Query: 300 GSSLPTPPPGLSPLSPQQ------QVQPSGSPARSLHS-QAPTSPRPS--LGPSTVGAPQ 350
GS + P L+P++P + Q GSP +AP +P P + V
Sbjct: 1150 GSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEIS 1209
Query: 351 TLPRSSLSA-FPAQPPVEELGQEQPQ 375
L + SA FP P+ LG P+
Sbjct: 1210 NLSQGDASASFPGSEPL--LGSPDPE 1233
Score = 34.7 bits (78), Expect = 0.18
Identities = 42/147 (28%), Positives = 58/147 (39%), Gaps = 38/147 (25%)
Query: 236 GSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPA-----QPLASSTPLSLSG--MPPVSF 288
G+ GPP S + SP +S + P A L P LSG + P SF
Sbjct: 2712 GAVGPPGSWGAEP-----SSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSF 2766
Query: 289 PAVHK----PPSSTPGSS---------------LPTPPPGLSPLSPQQQV---QPSGSPA 326
P+ + PP +TP S P PG PL QQQ Q + A
Sbjct: 2767 PSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAA 2826
Query: 327 RSLH----SQAPTSPRPSLGPSTVGAP 349
S+ ++ P++P P LG +G+P
Sbjct: 2827 TSMRFAMSARFPSTPGPELGRQALGSP 2853
Score = 34.3 bits (77), Expect = 0.24
Identities = 48/202 (23%), Positives = 71/202 (35%), Gaps = 39/202 (19%)
Query: 241 PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASST-----PLSLSG----MPPVSFPAV 291
P +P + + P+ P+SP+ A P S P G P++ P +
Sbjct: 919 PSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPIL 978
Query: 292 HKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQT 351
P S P ++ P P + P P G + L P P L S V PQ
Sbjct: 979 ETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLV--PQN 1036
Query: 352 LPRSSLSAFPAQP-----PVEELGQ------------------EQPQAVALLVSSKPKSA 388
P S S PA P P+ +G+ +P+ AL +P +
Sbjct: 1037 SPPSQCSP-PALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPAL----EPSAT 1091
Query: 389 VPLVHVKETVSKPYVTESPAED 410
PL +S P + +PA D
Sbjct: 1092 SPLPSPMGDLSCPAPSPAPALD 1113
Score = 33.5 bits (75), Expect = 0.40
Identities = 43/152 (28%), Positives = 54/152 (35%), Gaps = 34/152 (22%)
Query: 236 GSHGPPVSQPVQTL-------EFTCESPV-SAPVSPLEQPPAQPLASS------TPLSLS 281
GS+ P +QP T E C P S P P + PA P + S TP LS
Sbjct: 2372 GSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLS 2431
Query: 282 GMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSL 341
P + S P S P+ P P +P LH P P+P
Sbjct: 2432 AEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAP-------------LHK--PPRPQP-- 2474
Query: 342 GPSTVGAPQTLPRSSLSA--FPAQPPVEELGQ 371
P +L +SL A FPA P G+
Sbjct: 2475 -PEVAFKAGSLAHTSLGAGGFPAALPAGPAGE 2505
Score = 32.0 bits (71), Expect = 1.2
Identities = 36/118 (30%), Positives = 49/118 (41%), Gaps = 20/118 (16%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSL--SGMPPVSFPAVHKPPSS 297
PP +P T SP+ + Q P + PL +G P P + PP +
Sbjct: 4241 PPYQEPG-----TQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295
Query: 298 TP-----GSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQ 350
G PTPPP SPQ+ +PS P+ S SQ PT + L P+ G P+
Sbjct: 4296 LSTGPVLGPVHPTPPPS----SPQEPKRPSQLPSPS--SQLPTEAQ--LPPTHPGTPK 4345
Score = 32.0 bits (71), Expect = 1.2
Identities = 30/92 (32%), Positives = 37/92 (40%), Gaps = 12/92 (13%)
Query: 232 GDGRGSHGPP-VSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPA 290
G G GPP + P L PV PV P PP+ P P L P P
Sbjct: 4278 GAGPRPQGPPRLPAPPGALS---TGPVLGPVHPTP-PPSSPQEPKRPSQLPS-PSSQLPT 4332
Query: 291 VHKPPSSTPGSSLP-----TPPPG-LSPLSPQ 316
+ P + PG+ P PPPG +SP + Q
Sbjct: 4333 EAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQ 4364
Score = 32.0 bits (71), Expect = 1.2
Identities = 55/231 (23%), Positives = 82/231 (35%), Gaps = 26/231 (11%)
Query: 187 PRVEVYCQIELALGNECPERSQPSLRARQASLEGATQP--HKEWVPKGDGRGSHGPPVSQ 244
P + + G+ CP Q LR S T P + + + K + PP S
Sbjct: 4567 PAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSL 4626
Query: 245 PVQTLEFTCESPVSAPVSPLEQPPAQPL-ASSTPLSLSGMPPVSFPAVHKPPSSTPGSSL 303
P + V+ V+P E+ P A+S S + S + S ++L
Sbjct: 4627 PPTPPPSVQQKMVNG-VTPSEELGEHPKDAASARDSERALRDTS-----EVKSLDLLAAL 4680
Query: 304 PTPPPGLSP---------LSPQQQVQPSGSPARSLHSQAPTSPRPSLGP------STVGA 348
PTPP + + P+ SP L +AP P G +
Sbjct: 4681 PTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPV 4740
Query: 349 PQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVS 399
+PR+S+ FP P LG E P + + K K + V V TVS
Sbjct: 4741 IPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSE--VSVMLTVS 4789
Score = 29.3 bits (64), Expect = 7.6
Identities = 27/94 (28%), Positives = 33/94 (35%), Gaps = 23/94 (24%)
Query: 304 PTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQ 363
P P P P S R L + P P P P S L+ PA
Sbjct: 4884 PAPEP---PTQHSYTYNVSNLDVRQLSAPPPEEPSP-------------PPSPLAPSPAS 4927
Query: 364 PPVEELGQ-------EQPQAVALLVSSKPKSAVP 390
PP E L + E P L ++S P+SA P
Sbjct: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESARP 4961
>gi|117938768 GNAS complex locus alex [Homo sapiens]
Length = 626
Score = 57.0 bits (136), Expect = 3e-08
Identities = 62/190 (32%), Positives = 75/190 (39%), Gaps = 32/190 (16%)
Query: 205 ERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPL 264
E+ P LR +Q + P +E K RG+ P QP + PL
Sbjct: 286 EQRDPQLRRKQQRWKEPLMPRRE--EKYPLRGTDPLPPGQPQRI--------------PL 329
Query: 265 EQPPAQPLASSTPLSLSGMPP-VSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSG 323
P QP TP G P + P H+P TPG S P P PG PL P QP
Sbjct: 330 PGQPLQPQPILTP----GQPQKIPTPGQHQP-ILTPGHSQPIPTPG-QPLPP----QPIP 379
Query: 324 SPARSLHSQAPTSPRPSLGPSTV---GAPQTLPRSSLSAFPAQPPVEELGQEQ--PQAVA 378
+P R L Q +P L P + G P LP P QP +L Q Q P
Sbjct: 380 TPGRPLTPQPIPTPGRPLTPQPIQMPGRPLRLPPPLRLLRPGQPMSPQLRQTQGLPLPQP 439
Query: 379 LLVSSKPKSA 388
LL +PKSA
Sbjct: 440 LLPPGQPKSA 449
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 55.1 bits (131), Expect = 1e-07
Identities = 57/200 (28%), Positives = 76/200 (38%), Gaps = 20/200 (10%)
Query: 199 LGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVS 258
+G P QP L++ + P ++ P GP + QT S +
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
Query: 259 APVSPLEQPPAQPLASSTPLSLSGM--PPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQ 316
P P PP QP + P G PP P KPP PG + P+P S P
Sbjct: 475 GPAKP---PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 317 QQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQA 376
QQ S P+ +Q P+ +PS ST QT S P QPP +QP +
Sbjct: 532 QQ-PGSAKPS----AQQPSPAKPSAQQSTKPVSQT-----GSGKPLQPPTVSPSAKQPPS 581
Query: 377 VALLVSSKPKSAVPLVHVKE 396
L PK+ PL + E
Sbjct: 582 QGL-----PKTICPLCNTTE 596
Score = 54.7 bits (130), Expect = 2e-07
Identities = 61/256 (23%), Positives = 97/256 (37%), Gaps = 46/256 (17%)
Query: 223 QPHK-EWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPV-----------------SPL 264
QP K + P G G+ GP + + + S P SP
Sbjct: 243 QPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPS 302
Query: 265 EQPPAQPLASSTPLSLSG---------MPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSP 315
+ P QP P G PP + KP + PG+ P P + P
Sbjct: 303 KPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP 362
Query: 316 QQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRS-SLSAFPAQPPVEELGQEQP 374
Q + P+ PA+ S+ P+S +P GP + P + ++ + PA+PP +++G +P
Sbjct: 363 AQPLGPAKPPAQQTGSEKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 375 QAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKKNKQKTSGTR----- 429
A + S K+ P K V +P + PA+ + K + Q+T T+
Sbjct: 421 LAQQPGLQSPAKAPGP---TKTPVQQPGPGKIPAQQAG----PGKTSAQQTGPTKPPSQL 473
Query: 430 ----KGFPRHSGSKKP 441
K P+ G KP
Sbjct: 474 PGPAKPPPQQPGPAKP 489
Score = 43.9 bits (102), Expect = 3e-04
Identities = 47/221 (21%), Positives = 74/221 (33%), Gaps = 23/221 (10%)
Query: 201 NECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAP 260
++ PE +P +Q +L G+ + P+ D PP V + + P
Sbjct: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 261 VSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQ 320
P P L SS+ + P + + TPP P Q
Sbjct: 755 KQPKMVKPTTDLVSSSSATTK-------PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 321 PSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALL 380
P+G S+A PRP+ + P P S PV++ +E+P+
Sbjct: 808 PTGEKVSPFDSKA--IPRPASDSKIISHPG--PSSESKGQKQVDPVQK--KEEPKKAQTK 861
Query: 381 VSSKPKSAV----------PLVHVKETVSKPYVTESPAEDS 411
+S KP + P +TV P + P E S
Sbjct: 862 MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/160 (26%), Positives = 65/160 (40%), Gaps = 19/160 (11%)
Query: 258 SAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQ 317
S VS L P +P S+ L +S PP PP P P PPP PL P
Sbjct: 2380 SPSVSSLPAKP-RPFFRSSSLDISAQPP-------PPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 318 QVQPSGSPARSLHSQAP-TSPRP------SLGPSTVGAPQTLPRSSLSAFPAQPPVEELG 370
+P+ P + L +P T+ P +L + V LP + + A PPV
Sbjct: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT-TAPPPVPPKP 2490
Query: 371 QEQPQAVALLVSSKPKSAVPLVHVKETVSK-PYVTESPAE 409
P L+ + +P+ + P + K + + P T+ P +
Sbjct: 2491 SSIPS--GLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD 2528
Score = 30.8 bits (68), Expect = 2.6
Identities = 38/147 (25%), Positives = 59/147 (40%), Gaps = 10/147 (6%)
Query: 215 QASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLAS 274
+ASLEG P G G+ G P T + + A +S L + + +A+
Sbjct: 4 EASLEGEGLPEGLAAAAAAGGGASG--AGSPSHT---AIPAGMEADLSQLSEEERRQIAA 58
Query: 275 STPLSLSGMPPVSFP-AVHKPPSSTPGSSLPTP-PPGLS--PLSPQQQVQPSGSPARSLH 330
+ G+P S P A + PS L + PP S P P + QP S +R+
Sbjct: 59 VMSRA-QGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTD 117
Query: 331 SQAPTSPRPSLGPSTVGAPQTLPRSSL 357
+ P PST+ ++ R+ L
Sbjct: 118 TFRSEQKLPGRSPSTISLKESKSRTDL 144
Score = 29.3 bits (64), Expect = 7.6
Identities = 46/203 (22%), Positives = 70/203 (34%), Gaps = 21/203 (10%)
Query: 201 NECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPV-SQPVQTLEFTCESPVSA 259
++ E++ P L+ A + P E V D + P S+ + + ES
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 260 PVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQV 319
V P+ Q +P + T +S P P +P P P G + +PQQ
Sbjct: 845 QVDPV-QKKEEPKKAQTKMSPK-------PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896
Query: 320 QPSGSPARSLHSQAPTSPRPSLGPST-----------VGAPQTLPRSSLSAFPAQP-PVE 367
+P R + + P P+T GA S+L + QP P
Sbjct: 897 KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHS 956
Query: 368 ELGQEQPQAVALLVSSKPKSAVP 390
+ G P A S P S P
Sbjct: 957 QSGPGAPMKQAPAPSQPPTSQGP 979
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 55.1 bits (131), Expect = 1e-07
Identities = 57/200 (28%), Positives = 76/200 (38%), Gaps = 20/200 (10%)
Query: 199 LGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVS 258
+G P QP L++ + P ++ P GP + QT S +
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474
Query: 259 APVSPLEQPPAQPLASSTPLSLSGM--PPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQ 316
P P PP QP + P G PP P KPP PG + P+P S P
Sbjct: 475 GPAKP---PPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 317 QQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQA 376
QQ S P+ +Q P+ +PS ST QT S P QPP +QP +
Sbjct: 532 QQ-PGSAKPS----AQQPSPAKPSAQQSTKPVSQT-----GSGKPLQPPTVSPSAKQPPS 581
Query: 377 VALLVSSKPKSAVPLVHVKE 396
L PK+ PL + E
Sbjct: 582 QGL-----PKTICPLCNTTE 596
Score = 54.7 bits (130), Expect = 2e-07
Identities = 61/256 (23%), Positives = 97/256 (37%), Gaps = 46/256 (17%)
Query: 223 QPHK-EWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPV-----------------SPL 264
QP K + P G G+ GP + + + S P SP
Sbjct: 243 QPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPS 302
Query: 265 EQPPAQPLASSTPLSLSG---------MPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSP 315
+ P QP P G PP + KP + PG+ P P + P
Sbjct: 303 KPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP 362
Query: 316 QQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRS-SLSAFPAQPPVEELGQEQP 374
Q + P+ PA+ S+ P+S +P GP + P + ++ + PA+PP +++G +P
Sbjct: 363 AQPLGPAKPPAQQTGSEKPSSEQP--GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Query: 375 QAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKKNKQKTSGTR----- 429
A + S K+ P K V +P + PA+ + K + Q+T T+
Sbjct: 421 LAQQPGLQSPAKAPGP---TKTPVQQPGPGKIPAQQAG----PGKTSAQQTGPTKPPSQL 473
Query: 430 ----KGFPRHSGSKKP 441
K P+ G KP
Sbjct: 474 PGPAKPPPQQPGPAKP 489
Score = 43.9 bits (102), Expect = 3e-04
Identities = 47/221 (21%), Positives = 74/221 (33%), Gaps = 23/221 (10%)
Query: 201 NECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAP 260
++ PE +P +Q +L G+ + P+ D PP V + + P
Sbjct: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 261 VSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQ 320
P P L SS+ + P + + TPP P Q
Sbjct: 755 KQPKMVKPTTDLVSSSSATTK-------PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 321 PSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALL 380
P+G S+A PRP+ + P P S PV++ +E+P+
Sbjct: 808 PTGEKVSPFDSKA--IPRPASDSKIISHPG--PSSESKGQKQVDPVQK--KEEPKKAQTK 861
Query: 381 VSSKPKSAV----------PLVHVKETVSKPYVTESPAEDS 411
+S KP + P +TV P + P E S
Sbjct: 862 MSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/160 (26%), Positives = 65/160 (40%), Gaps = 19/160 (11%)
Query: 258 SAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQ 317
S VS L P +P S+ L +S PP PP P P PPP PL P
Sbjct: 2380 SPSVSSLPAKP-RPFFRSSSLDISAQPP-------PPPPPPPPPPPPPPPPPPPPLPPPT 2431
Query: 318 QVQPSGSPARSLHSQAP-TSPRP------SLGPSTVGAPQTLPRSSLSAFPAQPPVEELG 370
+P+ P + L +P T+ P +L + V LP + + A PPV
Sbjct: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICT-TAPPPVPPKP 2490
Query: 371 QEQPQAVALLVSSKPKSAVPLVHVKETVSK-PYVTESPAE 409
P L+ + +P+ + P + K + + P T+ P +
Sbjct: 2491 SSIPS--GLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD 2528
Score = 30.8 bits (68), Expect = 2.6
Identities = 38/147 (25%), Positives = 59/147 (40%), Gaps = 10/147 (6%)
Query: 215 QASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLAS 274
+ASLEG P G G+ G P T + + A +S L + + +A+
Sbjct: 4 EASLEGEGLPEGLAAAAAAGGGASG--AGSPSHT---AIPAGMEADLSQLSEEERRQIAA 58
Query: 275 STPLSLSGMPPVSFP-AVHKPPSSTPGSSLPTP-PPGLS--PLSPQQQVQPSGSPARSLH 330
+ G+P S P A + PS L + PP S P P + QP S +R+
Sbjct: 59 VMSRA-QGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTD 117
Query: 331 SQAPTSPRPSLGPSTVGAPQTLPRSSL 357
+ P PST+ ++ R+ L
Sbjct: 118 TFRSEQKLPGRSPSTISLKESKSRTDL 144
Score = 29.3 bits (64), Expect = 7.6
Identities = 46/203 (22%), Positives = 70/203 (34%), Gaps = 21/203 (10%)
Query: 201 NECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPV-SQPVQTLEFTCESPVSA 259
++ E++ P L+ A + P E V D + P S+ + + ES
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK 844
Query: 260 PVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQV 319
V P+ Q +P + T +S P P +P P P G + +PQQ
Sbjct: 845 QVDPV-QKKEEPKKAQTKMSPK-------PDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896
Query: 320 QPSGSPARSLHSQAPTSPRPSLGPST-----------VGAPQTLPRSSLSAFPAQP-PVE 367
+P R + + P P+T GA S+L + QP P
Sbjct: 897 KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHS 956
Query: 368 ELGQEQPQAVALLVSSKPKSAVP 390
+ G P A S P S P
Sbjct: 957 QSGPGAPMKQAPAPSQPPTSQGP 979
>gi|71274152 hypothetical protein LOC388939 [Homo sapiens]
Length = 1288
Score = 55.1 bits (131), Expect = 1e-07
Identities = 54/179 (30%), Positives = 81/179 (45%), Gaps = 19/179 (10%)
Query: 197 LALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESP 256
LA + ERS P R+AS T+ H WVP+ D R P +P Q ++P
Sbjct: 977 LARPRQSRERSPPV--GRKAS---PTRTH--WVPQADKRRRSLPSSYRPAQPSPSAVQTP 1029
Query: 257 VSAPVSP-LEQPPAQPLASSTP--LSLSGMPPVSFPAVHKPPS-------STPGSSLPTP 306
S PVSP + PP +S P L PP S PA K PS ++P S+P+P
Sbjct: 1030 PSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPPESAPAQCKVPSPPTQHPEASPPFSIPSP 1089
Query: 307 PPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPP 365
P +SP ++ + S ++++ ++ + P+T + P S +A P PP
Sbjct: 1090 SPPMSPSQEHKETRDS-EDSQAVIAKVSGNTHSIFCPATSSLFEAKPPLS-TAHPLTPP 1146
Score = 34.7 bits (78), Expect = 0.18
Identities = 53/237 (22%), Positives = 86/237 (36%), Gaps = 37/237 (15%)
Query: 215 QASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPL-- 272
+ +LE P E + P S+ + + P P + A P
Sbjct: 824 EGNLEHLPPPPMEVLMDKSFASLESPESSKSTENSPKETQEPGPGEAGPTRRTWASPKLR 883
Query: 273 ASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQ 332
AS +PL L +P S ++ KP S+ PGS G S P++ PA L S
Sbjct: 884 ASVSPLDL--LPSKSTASLTKPHSTGPGS-------GRSSCQPRK-------PALDLSSP 927
Query: 333 APTSPRPSLGPSTVGAPQTL------PRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPK 386
TS P + T + PR +++ + PP GQ + +L + +
Sbjct: 928 PATSQSPEVKGGTWSQAEKATSLYRQPRKAIAWHHSGPP---SGQNRTSESSLARPRQSR 984
Query: 387 SAVPLVHVKETVSKPYVTESPAEDSNWVNKVFKKNKQKTSGTRKGFPRHSGSKKPSS 443
P V K + ++ ++WV + K+ + S R P S + P S
Sbjct: 985 ERSPPVGRKASPTR----------THWVPQADKRRRSLPSSYRPAQPSPSAVQTPPS 1031
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 53.5 bits (127), Expect = 4e-07
Identities = 56/206 (27%), Positives = 75/206 (36%), Gaps = 38/206 (18%)
Query: 209 PSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPP 268
P+ R QA GA PH + P G G GPP+ S V P + PP
Sbjct: 201 PTSRMFQAP-PGAPPPHPQLYPGGTGGVLSGPPMGPKGGG----AASSVGGPNGGKQHPP 255
Query: 269 AQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPT---------------PPPGLSPL 313
+TP+S+S P P + G +LP+ PPP L PL
Sbjct: 256 P-----TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPL 310
Query: 314 SPQQQVQPSGSPARSLHSQAPT-----------SPRPSLGPSTVGAPQTLPRSSLSAFPA 362
+ P G A+ L P+ P P GP+ +P +LP +S SA PA
Sbjct: 311 N-NASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSA-PA 368
Query: 363 QPPVEELGQEQPQAVALLVSSKPKSA 388
P + A SS S+
Sbjct: 369 PPMRFPYSSSSSSSAAASSSSSSSSS 394
Score = 37.7 bits (86), Expect = 0.021
Identities = 42/146 (28%), Positives = 60/146 (41%), Gaps = 10/146 (6%)
Query: 230 PKGDGRGSHG-PPVSQPVQTLEFTCES----PVSAPVSPLEQPPAQPLASSTPLSLSGMP 284
P G+G G PP + TL + S SAP P+ P + +SS S S
Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 285 PVSFPAVHKPPSSTPGSSLPTPPPGLSPLS--PQQQVQPSGSPARSLHSQAPTSPRP--S 340
S + + P PPP +S P + QPS P++++ SQ P P P
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS-LPSQAVWSQGPPPPPPYGR 450
Query: 341 LGPSTVGAPQTLPRSSLSAFPAQPPV 366
L ++ P P S+ + A PPV
Sbjct: 451 LLANSNAHPGPFPPSTGAQSTAHPPV 476
Score = 35.4 bits (80), Expect = 0.11
Identities = 30/105 (28%), Positives = 37/105 (35%), Gaps = 17/105 (16%)
Query: 267 PPAQPLASSTPLSLSGMPPVSFPAVHKPPSST--PGSSLPTPPPGLSPLSPQQQVQPSGS 324
PP+ + TP G P + P KP S T PG P P GL L P SG
Sbjct: 662 PPS--FRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719
Query: 325 PARSL-------------HSQAPTSPRPSLGPSTVGAPQTLPRSS 356
P + S P + PS P V P +S+
Sbjct: 720 PLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSA 764
Score = 35.0 bits (79), Expect = 0.14
Identities = 47/183 (25%), Positives = 60/183 (32%), Gaps = 24/183 (13%)
Query: 200 GNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSA 259
G + P + P + + GA P G G PP P T P
Sbjct: 250 GKQHPPPTTP-ISVSSSGASGAPPTKPPTTPVGGGNLPSAPP---PANFPHVTPNLPPPP 305
Query: 260 PVSPLEQ----PP---AQPLASSTPL------SLSGMPP--VSFPAVHKPPSSTP--GSS 302
+ PL PP AQPL P + G+PP P + P S P SS
Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365
Query: 303 LPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPA 362
P PP S + S + S S A P PS P + P + +
Sbjct: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPS---YPHSFPPPTSLSVSN 422
Query: 363 QPP 365
QPP
Sbjct: 423 QPP 425
Score = 34.3 bits (77), Expect = 0.24
Identities = 38/135 (28%), Positives = 48/135 (35%), Gaps = 18/135 (13%)
Query: 262 SPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPT--PPPGLSPLSPQQQV 319
S L Q PA+P PP FP +PP STP + P P ++P +
Sbjct: 149 SGLSQGPARPYH----------PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPM 198
Query: 320 QPSGSPARSLHSQAPTSPRPSLGPSTVG----APQTLPRSSLSAFPAQPPVEELGQEQPQ 375
+P S AP P P L P G P P+ +A P Q P
Sbjct: 199 EPPTSRMFQAPPGAP-PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGP-NGGKQHPPP 256
Query: 376 AVALLVSSKPKSAVP 390
+ VSS S P
Sbjct: 257 TTPISVSSSGASGAP 271
Score = 33.5 bits (75), Expect = 0.40
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 5/55 (9%)
Query: 265 EQPPAQPLASSTPLSLSGMPPVSFPAV----HKPPSSTPGSSLPTPPPGLSPLSP 315
E+ + L S L+ G PV P++ H+PP PGS++ T PP L P +P
Sbjct: 828 EREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFE-PGSAVATVPPYLGPDTP 881
Score = 31.6 bits (70), Expect = 1.5
Identities = 43/167 (25%), Positives = 52/167 (31%), Gaps = 16/167 (9%)
Query: 218 LEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTP 277
LEG + H GS P P P + VS + P P SS+
Sbjct: 519 LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL------PPPHSQVSYSQAGPNGPPVSSSS 572
Query: 278 LSLSGMPPVSFPAVHKPPSSTP-GSSLPTPP--------PGLSPLSPQQQVQPSGSPARS 328
S S S+P H PS P G+ P PP LS + P+G S
Sbjct: 573 NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTAS 632
Query: 329 LHSQAPTSPR-PSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQP 374
P R PS G P S +F P G P
Sbjct: 633 PPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPP 679
Score = 31.2 bits (69), Expect = 2.0
Identities = 31/104 (29%), Positives = 37/104 (35%), Gaps = 15/104 (14%)
Query: 207 SQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAP--VSPL 264
S PS R T P P G G G P P P + P + L
Sbjct: 661 SPPSFRTGTPPGYRGTSP-----PAGPGTFKPGSPTVGPGPL-------PPAGPSGLPSL 708
Query: 265 EQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPP 308
PPA P AS PLS + + P S P + P+PPP
Sbjct: 709 PPPPAAP-ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
Score = 29.6 bits (65), Expect = 5.8
Identities = 32/126 (25%), Positives = 43/126 (34%), Gaps = 21/126 (16%)
Query: 224 PHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESP-----VSAPVSPLEQPPAQPLASSTPL 278
P+ + P + PP +P F +P S P P P P PL
Sbjct: 638 PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPL 697
Query: 279 SLSGM-------PPVSFPAVHKPPSST-----PGSSLPTP----PPGLSPLSPQQQVQPS 322
+G PP + PA P S+T P TP PP SP P + V
Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVP 757
Query: 323 GSPARS 328
++S
Sbjct: 758 SHASQS 763
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 53.5 bits (127), Expect = 4e-07
Identities = 56/206 (27%), Positives = 75/206 (36%), Gaps = 38/206 (18%)
Query: 209 PSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPP 268
P+ R QA GA PH + P G G GPP+ S V P + PP
Sbjct: 201 PTSRMFQAP-PGAPPPHPQLYPGGTGGVLSGPPMGPKGGG----AASSVGGPNGGKQHPP 255
Query: 269 AQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPT---------------PPPGLSPL 313
+TP+S+S P P + G +LP+ PPP L PL
Sbjct: 256 P-----TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPL 310
Query: 314 SPQQQVQPSGSPARSLHSQAPT-----------SPRPSLGPSTVGAPQTLPRSSLSAFPA 362
+ P G A+ L P+ P P GP+ +P +LP +S SA PA
Sbjct: 311 N-NASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSA-PA 368
Query: 363 QPPVEELGQEQPQAVALLVSSKPKSA 388
P + A SS S+
Sbjct: 369 PPMRFPYSSSSSSSAAASSSSSSSSS 394
Score = 37.7 bits (86), Expect = 0.021
Identities = 42/146 (28%), Positives = 60/146 (41%), Gaps = 10/146 (6%)
Query: 230 PKGDGRGSHG-PPVSQPVQTLEFTCES----PVSAPVSPLEQPPAQPLASSTPLSLSGMP 284
P G+G G PP + TL + S SAP P+ P + +SS S S
Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 285 PVSFPAVHKPPSSTPGSSLPTPPPGLSPLS--PQQQVQPSGSPARSLHSQAPTSPRP--S 340
S + + P PPP +S P + QPS P++++ SQ P P P
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS-LPSQAVWSQGPPPPPPYGR 450
Query: 341 LGPSTVGAPQTLPRSSLSAFPAQPPV 366
L ++ P P S+ + A PPV
Sbjct: 451 LLANSNAHPGPFPPSTGAQSTAHPPV 476
Score = 35.4 bits (80), Expect = 0.11
Identities = 30/105 (28%), Positives = 37/105 (35%), Gaps = 17/105 (16%)
Query: 267 PPAQPLASSTPLSLSGMPPVSFPAVHKPPSST--PGSSLPTPPPGLSPLSPQQQVQPSGS 324
PP+ + TP G P + P KP S T PG P P GL L P SG
Sbjct: 662 PPS--FRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719
Query: 325 PARSL-------------HSQAPTSPRPSLGPSTVGAPQTLPRSS 356
P + S P + PS P V P +S+
Sbjct: 720 PLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSA 764
Score = 35.0 bits (79), Expect = 0.14
Identities = 47/183 (25%), Positives = 60/183 (32%), Gaps = 24/183 (13%)
Query: 200 GNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSA 259
G + P + P + + GA P G G PP P T P
Sbjct: 250 GKQHPPPTTP-ISVSSSGASGAPPTKPPTTPVGGGNLPSAPP---PANFPHVTPNLPPPP 305
Query: 260 PVSPLEQ----PP---AQPLASSTPL------SLSGMPP--VSFPAVHKPPSSTP--GSS 302
+ PL PP AQPL P + G+PP P + P S P SS
Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365
Query: 303 LPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPA 362
P PP S + S + S S A P PS P + P + +
Sbjct: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPS---YPHSFPPPTSLSVSN 422
Query: 363 QPP 365
QPP
Sbjct: 423 QPP 425
Score = 34.3 bits (77), Expect = 0.24
Identities = 38/135 (28%), Positives = 48/135 (35%), Gaps = 18/135 (13%)
Query: 262 SPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPT--PPPGLSPLSPQQQV 319
S L Q PA+P PP FP +PP STP + P P ++P +
Sbjct: 149 SGLSQGPARPYH----------PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPM 198
Query: 320 QPSGSPARSLHSQAPTSPRPSLGPSTVG----APQTLPRSSLSAFPAQPPVEELGQEQPQ 375
+P S AP P P L P G P P+ +A P Q P
Sbjct: 199 EPPTSRMFQAPPGAP-PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGP-NGGKQHPPP 256
Query: 376 AVALLVSSKPKSAVP 390
+ VSS S P
Sbjct: 257 TTPISVSSSGASGAP 271
Score = 33.5 bits (75), Expect = 0.40
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 5/55 (9%)
Query: 265 EQPPAQPLASSTPLSLSGMPPVSFPAV----HKPPSSTPGSSLPTPPPGLSPLSP 315
E+ + L S L+ G PV P++ H+PP PGS++ T PP L P +P
Sbjct: 828 EREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFE-PGSAVATVPPYLGPDTP 881
Score = 31.6 bits (70), Expect = 1.5
Identities = 43/167 (25%), Positives = 52/167 (31%), Gaps = 16/167 (9%)
Query: 218 LEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTP 277
LEG + H GS P P P + VS + P P SS+
Sbjct: 519 LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL------PPPHSQVSYSQAGPNGPPVSSSS 572
Query: 278 LSLSGMPPVSFPAVHKPPSSTP-GSSLPTPP--------PGLSPLSPQQQVQPSGSPARS 328
S S S+P H PS P G+ P PP LS + P+G S
Sbjct: 573 NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTAS 632
Query: 329 LHSQAPTSPR-PSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQP 374
P R PS G P S +F P G P
Sbjct: 633 PPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPP 679
Score = 31.2 bits (69), Expect = 2.0
Identities = 31/104 (29%), Positives = 37/104 (35%), Gaps = 15/104 (14%)
Query: 207 SQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAP--VSPL 264
S PS R T P P G G G P P P + P + L
Sbjct: 661 SPPSFRTGTPPGYRGTSP-----PAGPGTFKPGSPTVGPGPL-------PPAGPSGLPSL 708
Query: 265 EQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPP 308
PPA P AS PLS + + P S P + P+PPP
Sbjct: 709 PPPPAAP-ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
Score = 29.6 bits (65), Expect = 5.8
Identities = 32/126 (25%), Positives = 43/126 (34%), Gaps = 21/126 (16%)
Query: 224 PHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESP-----VSAPVSPLEQPPAQPLASSTPL 278
P+ + P + PP +P F +P S P P P P PL
Sbjct: 638 PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPL 697
Query: 279 SLSGM-------PPVSFPAVHKPPSST-----PGSSLPTP----PPGLSPLSPQQQVQPS 322
+G PP + PA P S+T P TP PP SP P + V
Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVP 757
Query: 323 GSPARS 328
++S
Sbjct: 758 SHASQS 763
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 53.5 bits (127), Expect = 4e-07
Identities = 48/175 (27%), Positives = 66/175 (37%), Gaps = 13/175 (7%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSG------MPPVSFPAVHK 293
PP P + + + V P P A P P SLS +PP S +
Sbjct: 556 PPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP 615
Query: 294 PP-SSTPGSSLPTPPPGLSP------LSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTV 346
PP P S TPPPG+ P + PQ P + S SQ P PRP+L P+ V
Sbjct: 616 PPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPV 675
Query: 347 GAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKP 401
P + + P E++ + P + + L S S L S+P
Sbjct: 676 SFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQP 730
Score = 51.2 bits (121), Expect = 2e-06
Identities = 65/223 (29%), Positives = 81/223 (36%), Gaps = 27/223 (12%)
Query: 208 QPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPV---SQPVQTLEFTCESPVSAPVSPL 264
Q ++A Q+ L+ + + G S PP SQ L T PV P P
Sbjct: 486 QGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLP-TMPPPVLPPSLP- 543
Query: 265 EQPPAQPLASSTPLSLSGMPPV----SFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQ 320
PP P A + GMPP S P PP P S PPP L P S
Sbjct: 544 --PPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGP 601
Query: 321 PSGSPARSLHSQA--PTSPRPSLGPST-------VGAPQTLPRSSLSAFPAQPPVEELGQ 371
P P SL S A P P P L +T G PQ +P L+A P P
Sbjct: 602 PPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIP-PQLTAAPVPPASSSQSS 660
Query: 372 EQPQ--AVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSN 412
+ P+ ALL + + P T P + P+E N
Sbjct: 661 QVPEKPRPALLPTPVSFGSAP----PTTYHPPLQSAGPSEQVN 699
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/131 (32%), Positives = 55/131 (41%), Gaps = 23/131 (17%)
Query: 262 SPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQP 321
SP E PP P S P S S MPP P + PP+S+ P L P P
Sbjct: 145 SPPESPPVPP-GSYMPPSQSYMPPPQPPPSYYPPTSS--------QPYLPPAQP------ 189
Query: 322 SGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSS--LSAFPAQPPVEELGQEQPQAVAL 379
SP++S SQ+ +P PS S+ + L S L + A P G + Q
Sbjct: 190 --SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ---- 243
Query: 380 LVSSKPKSAVP 390
L++ P SA P
Sbjct: 244 LLAPPPPSAPP 254
Score = 38.5 bits (88), Expect = 0.012
Identities = 43/147 (29%), Positives = 58/147 (39%), Gaps = 33/147 (22%)
Query: 237 SHGPPVSQPVQTLEFTCESPVSAPVSPLEQ--------PPAQPLASSTPLSLSGMPPVSF 288
S GPP P +L T PV P+ PL PP P L+ + +PP S
Sbjct: 598 SAGPPPVLPPPSLSSTAPPPVM-PLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASS 656
Query: 289 PAVHKPPSSTPGSSLPTPP-----------PGLSPLSPQQQVQPSGSPARSLHSQAPTSP 337
+ P + LPTP P L P +QV +S+AP S
Sbjct: 657 SQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQV----------NSKAPLS- 705
Query: 338 RPSLGPSTVGAPQTLPRSSLSAFPAQP 364
+ +L S+ + Q L S SA P+QP
Sbjct: 706 KSALPYSSFSSDQGLGES--SAAPSQP 730
Score = 35.4 bits (80), Expect = 0.11
Identities = 54/221 (24%), Positives = 75/221 (33%), Gaps = 30/221 (13%)
Query: 218 LEGATQPHKEWVPKGD---GRGSHGPPVSQPVQTLEFTCESPVSAPV--SPLEQPPAQPL 272
+E + P VP G S+ PP P T P P SP + PP+Q
Sbjct: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSY 200
Query: 273 ASSTPLSLSGMP-------------PVSFPAVHKPPSSTPGSSLPTPPPGLSP----LSP 315
+ TP S P S + +P S L PPP +P +
Sbjct: 201 LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV 260
Query: 316 QQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLP----RSSLSAFPAQPPVEELGQ 371
QQ+ SG+ +S Q +P P PST+ PQ R L + + V G
Sbjct: 261 QQEPLESGAKNKSTEQQ-QAAPEPD--PSTM-TPQEQQQYWYRQHLLSLQQRTKVHLPGH 316
Query: 372 EQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDSN 412
++ VA K V + + P E P N
Sbjct: 317 KKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPN 357
Score = 34.3 bits (77), Expect = 0.24
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Query: 260 PVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSP 312
P P+ +PP + S P + S + PV+ P V PP P LP PPP + P
Sbjct: 1514 PPPPMGKPPGSIVRPSAPPARSSV-PVTRPPVPIPPPPPP-PPLPPPPPVIKP 1564
Score = 30.8 bits (68), Expect = 2.6
Identities = 27/73 (36%), Positives = 31/73 (42%), Gaps = 15/73 (20%)
Query: 287 SFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARS--------LHSQAPTSPR 338
S P ++ PP GS P PP G P S V+PS PARS + P P
Sbjct: 1501 SRPGMYPPP----GSYRPPPPMGKPPGS---IVRPSAPPARSSVPVTRPPVPIPPPPPPP 1553
Query: 339 PSLGPSTVGAPQT 351
P P V PQT
Sbjct: 1554 PLPPPPPVIKPQT 1566
Score = 30.4 bits (67), Expect = 3.4
Identities = 39/169 (23%), Positives = 58/169 (34%), Gaps = 27/169 (15%)
Query: 283 MPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLG 342
+PP P P G P PPP P P Q + P P L
Sbjct: 81 LPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP-PGLV 139
Query: 343 PSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPY 402
P + +P P PPV G P + + + +P P + T S+PY
Sbjct: 140 PMELESP-----------PESPPVPP-GSYMPPSQSYMPPPQP----PPSYYPPTSSQPY 183
Query: 403 V-------TESPAEDSNWVNKVFKKNKQKTSGTRKGFPRHSGSKKPSSK 444
+ ++SP S + +S + + + HS S PSS+
Sbjct: 184 LPPAQPSPSQSPPSQSYLAP---TPSYSSSSSSSQSYLSHSQSYLPSSQ 229
Score = 30.0 bits (66), Expect = 4.4
Identities = 32/149 (21%), Positives = 51/149 (34%), Gaps = 9/149 (6%)
Query: 282 GMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSL 341
G+ P+ + + P PGS +P + P P P P S P P PS
Sbjct: 137 GLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYP---PTSSQPYLPPAQPSPSQ 193
Query: 342 GPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKP 401
P + P S S+ +Q + P + A S+P H K + P
Sbjct: 194 SPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQA--SPSRPSQG----HSKSQLLAP 247
Query: 402 YVTESPAEDSNWVNKVFKKNKQKTSGTRK 430
+P + V + ++ K T +
Sbjct: 248 PPPSAPPGNKTTVQQEPLESGAKNKSTEQ 276
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 52.8 bits (125), Expect = 6e-07
Identities = 79/289 (27%), Positives = 99/289 (34%), Gaps = 58/289 (20%)
Query: 198 ALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPV 257
AL P+ S L++ SLE H+ W S G P+S F+ +P+
Sbjct: 773 ALPVPLPDPSNEELQS-STSLE-----HRSWTAFSTSSSSPGTPLSPGNP---FSPGTPI 823
Query: 258 S-APVSPLEQPPAQPLAS------------------STPLSLSGMPPVSFPAVHKPPSST 298
S P+ P+ PP P S S+PL S P FP P S
Sbjct: 824 SPGPIFPITSPPCHPSPSPFSPISSQVSSNPSPHPTSSPLPFSSSTP-EFPV---PLSQC 879
Query: 299 PGSSLPTP-PPGLSPLSPQQQVQ-PSGSPARSLHSQAPTSPRPSLG-------------- 342
P SSLPT PP SP Q + P P S S T+ P L
Sbjct: 880 PWSSLPTTSPPTFSPTCSQVTLSSPFFPPCPSTSSFPSTTAAPLLSLASAFSLAVMTVAQ 939
Query: 343 ------PSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSK--PKSAVPLVHV 394
P + P S L + P PPV GQE P V S+ P A PL
Sbjct: 940 SLLSPSPGLLSQSPPAPPSPLPSLPLPPPVAPGGQESPSPHTAEVESEASPPPARPL--P 997
Query: 395 KETVSKPYVTESPAEDSNWVNKVFKKNKQKTSGTRKGFPRHSGSKKPSS 443
E P E + K + + P SGS KPS+
Sbjct: 998 GEARLAPISEEGKPQLVGRFQVTSSKEPAEPLPLQPTSPTLSGSPKPST 1046
Score = 31.6 bits (70), Expect = 1.5
Identities = 40/141 (28%), Positives = 51/141 (36%), Gaps = 15/141 (10%)
Query: 241 PVSQPVQTLEFTCESPVSAPV-SPLEQPPAQPL---ASSTPLSLSGMPPVSFPAVHKPPS 296
P+ PV SP +A V S PPA+PL A P+S G P +
Sbjct: 964 PLPPPVAPGGQESPSPHTAEVESEASPPPARPLPGEARLAPISEEGKPQLV------GRF 1017
Query: 297 STPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSS 356
S P P L P SP P S + + T GP T + L S
Sbjct: 1018 QVTSSKEPAEPLPLQPTSPTLSGSPKPSTPQLTSESSDTEDSAGGGPET---REALAESD 1074
Query: 357 LSAFPAQPPVEELGQE--QPQ 375
+A VEE G + +PQ
Sbjct: 1075 RAAEGLGAGVEEEGDDGKEPQ 1095
>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
Length = 355
Score = 51.6 bits (122), Expect = 1e-06
Identities = 55/200 (27%), Positives = 79/200 (39%), Gaps = 33/200 (16%)
Query: 205 ERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQ-----TLEFTCESPVSA 259
E+ Q +R +AS E A GD PP +PV +E + P++
Sbjct: 151 EKLQEVVRKPRASQELA----------GDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAM 200
Query: 260 PVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQV 319
P PL P+ L P + +PP FP V +P S + P L P P Q+
Sbjct: 201 PPYPLPYSPSPSLPVG-PTAHGALPPAPFPVVSQP-------SFYSGP--LGPTYPAAQL 250
Query: 320 QPSGSPARSLHSQAPTSPRPS-----LGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQP 374
P G+ S Q PRP +G S G P R+ +P Q P G + P
Sbjct: 251 GPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPP 310
Query: 375 QAVALLVSS---KPKSAVPL 391
+ + S +P+ +VPL
Sbjct: 311 YPIQPQLPSFPGQPQPSVPL 330
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/185 (28%), Positives = 66/185 (35%), Gaps = 23/185 (12%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQP--LASSTPLSLSGMPPVSFPAVHKPPSS 297
P + P SP AP +P PP+ LA+ +P P + P+ P++
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257
Query: 298 TPGSSLPTPPPGLSPL------------SPQQQV----QPSGSPARSLHSQAPTSPRPSL 341
P PTPP P +P V P G PA S APT P +
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP-AAT 1316
Query: 342 GPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKP 401
PS G+P T P PA P G P A SSK P KE + P
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKG--TPTLPATTPSSKGGPTTP--SSKEGPTPP 1372
Query: 402 YVTES 406
T S
Sbjct: 1373 AATPS 1377
Score = 51.6 bits (122), Expect = 1e-06
Identities = 71/248 (28%), Positives = 98/248 (39%), Gaps = 47/248 (18%)
Query: 216 ASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASS 275
+S EG T P KG GP ++ P SP P SP P + A +
Sbjct: 1364 SSKEGPTPPAATPSHKG------GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA 1417
Query: 276 TPLSLSGM---------PPVSFPAVHK--PPSSTPGSSLPTPP-------PGLSPLSPQQ 317
TP++ G PP P K P +S P TP P ++P SP++
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
Query: 318 QVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQA- 376
P S +AP +P P +GAP TLP + + + P + P + P A
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAP------MGAP-TLP-AVIPSSPKEVPATPSSRRDPIAP 1529
Query: 377 VALLVSSK------PKSAV--PLVHV---KETVSKPYVTESPAEDSNWVNKVFKKNKQKT 425
A L+S K PK A+ P + V K+T + P E+PA S +K T
Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS---SKEASSPPAVT 1586
Query: 426 SGTRKGFP 433
T KG P
Sbjct: 1587 PSTYKGAP 1594
Score = 48.9 bits (115), Expect = 9e-06
Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 23/195 (11%)
Query: 206 RSQPSLRARQASLEGA-TQPHKEWVPKGDG-RGSHGPPVSQPVQTLEFTCE-SPVSAPVS 262
+ P+L +S + A P + +P +G+ PP + P SP AP
Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965
Query: 263 PLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTP-----PPGLSPLSPQQ 317
P PP+ +TP S G P P PPS G + P+P PP ++P SP+
Sbjct: 966 PAATPPSPKGGPATP-SPKGAPT---PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK- 1020
Query: 318 QVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQT--LPRSSLSAFPAQPPVEELGQEQPQ 375
GSPA + + ++P + PS G+P LP+ + + A P + G P
Sbjct: 1021 -----GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---PA 1072
Query: 376 AVALLVSSKPKSAVP 390
+L + P +A P
Sbjct: 1073 TPSLKGAPTPPAATP 1087
Score = 47.4 bits (111), Expect = 3e-05
Identities = 56/216 (25%), Positives = 77/216 (35%), Gaps = 41/216 (18%)
Query: 204 PERSQPSLRARQA--SLEGATQPHKEWVPKGDG--------RGSHGPPVSQPVQTLEFTC 253
P + PS + A S +GA P P G +G+ PP + P
Sbjct: 989 PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 254 ESPV--SAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTP----- 306
+P+ AP +P P+ +TP SL G P P PPS G + P+P
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATP-SLKGAPT---PPAATPPSPKGGPATPSPKGAPM 1104
Query: 307 PPGLSPLSPQQQVQPSGSPARSLHSQAPTSPR--------------PSLGPSTVGAPQTL 352
PP +P SP+ G A H APT+P P P+T A
Sbjct: 1105 PPAATPPSPK------GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158
Query: 353 PRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSA 388
P+ L+ P + P L + PK A
Sbjct: 1159 PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA 1194
Score = 43.9 bits (102), Expect = 3e-04
Identities = 43/143 (30%), Positives = 56/143 (39%), Gaps = 8/143 (5%)
Query: 235 RGSHGPPVSQPVQTLEFTCE-SPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHK 293
+G+ PP + P SP AP P PP+ +P + S P
Sbjct: 983 KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSP---KGSPAATPFPKGASTPPAAT 1039
Query: 294 PPSSTPGSSLPTPPPGLSPLSPQQQV-QPSGSPARSLHSQAPTSPRPSLGPSTVGAPQT- 351
PP S GS TP P +P +P + P G PA APT P + PS G P T
Sbjct: 1040 PP-SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP-AATPPSPKGGPATP 1097
Query: 352 LPRSSLSAFPAQPPVEELGQEQP 374
P+ + A PP + G P
Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATP 1120
Score = 43.9 bits (102), Expect = 3e-04
Identities = 56/200 (28%), Positives = 74/200 (37%), Gaps = 38/200 (19%)
Query: 204 PERSQPSLRARQA--SLEGATQPHKEWVPKGDG-------RGSHGPPVSQPVQTLEFTCE 254
P + PS + A SL+GA P P G +G+ PP + P
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119
Query: 255 SP-VSAPVSPLEQPP------AQPLASSTPLSLSGMPPVSFPAVHKPPS----STPGSSL 303
P AP +P PP A P P + + PP + PP +TP ++
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 304 PTPPPGLSPLSPQ--------QQVQPSGSPARSLHSQAPTS-----PRPSLG---PSTVG 347
P+P GL+ SP+ P G A APT+ P P G PS G
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239
Query: 348 APQTLPRS--SLSAFPAQPP 365
AP T + S PA PP
Sbjct: 1240 APTTPAATPPSPKGGPATPP 1259
Score = 42.4 bits (98), Expect = 9e-04
Identities = 43/176 (24%), Positives = 61/176 (34%), Gaps = 17/176 (9%)
Query: 235 RGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPL---ASSTPLSLSGMPPVSFPAV 291
+G+ PP + P P +P P P A+S P P + P+
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320
Query: 292 HKPPSSTPGSSLPTPP------PGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPST 345
P + P PTPP P +P P G P + PT P + PS
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT--PSH 1378
Query: 346 VGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKP 401
G P P S P + P + P + A++ S PK A +E + P
Sbjct: 1379 KGGPAMTPPS-----PKRGPAIPSPKGDPTSPAVIPLS-PKKAPATPVTREGAATP 1428
Score = 41.2 bits (95), Expect = 0.002
Identities = 47/169 (27%), Positives = 67/169 (39%), Gaps = 16/169 (9%)
Query: 204 PERSQPSLRARQASL--EGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPV 261
P + PSL+ A+ +GA P P G + PP P T SP +P
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-TPPSPKGSPG 1325
Query: 262 SPLEQPPAQPLASSTPLSLSGMP--PVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQV 319
+P + P A TP S G P P + P+ P++ PTPP +P +
Sbjct: 1326 TPPPKGAPTPPAV-TPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA----TPSHKG 1380
Query: 320 QPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEE 368
P+ +P + P P P P+ +P +P S A PA P E
Sbjct: 1381 GPAMTPPSP--KRGPAIPSPKGDPT---SPAVIPLSPKKA-PATPVTRE 1423
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/173 (28%), Positives = 68/173 (39%), Gaps = 37/173 (21%)
Query: 235 RGSHGPP-----VSQPVQTLE--FTCESPVS------APVSPLEQPPAQPLASSTPLSLS 281
+GS GP +S PV +E F E+ +S +P + P P + TP S
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTP---S 868
Query: 282 GMPPVSFPAVHKPPSSTPGSS---LPTPPPGLSPLSPQQQVQ----------------PS 322
+ P+S V PP TP S LP P G + +P+Q P
Sbjct: 869 AVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928
Query: 323 GSPARSLHSQAPTSPRPSLGPSTVGAPQT-LPRSSLSAFPAQPPVEELGQEQP 374
G PA APT P + PS G P T P+ + + A PP + G P
Sbjct: 929 GIPASPSPKGAPTPP-AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980
Score = 39.7 bits (91), Expect = 0.006
Identities = 62/222 (27%), Positives = 82/222 (36%), Gaps = 32/222 (14%)
Query: 204 PERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGP-PVSQPVQTLEFTCESPVSAPVS 262
P + P+ + Q AT P P GS GP P L +S +A
Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPSAKN-GSKGPLSTVAPAPLLPVQKDSSKTAKGK 1752
Query: 263 PLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGL----SP---LSP 315
P PLA + + + +F V P S S+ P+PP L SP L P
Sbjct: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPP 1812
Query: 316 QQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQ 375
+QQ PS SP L S P+ P P P PP E + P
Sbjct: 1813 KQQFLPS-SPGLVLES--PSKP-------------LAPADEDELLPLIPP-EPISGGVPF 1855
Query: 376 AVALLVSSKPKSA---VPLVHVKETVSKPYV---TESPAEDS 411
L+ PKSA VP K+ V+K TES +++S
Sbjct: 1856 QSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDES 1897
Score = 38.1 bits (87), Expect = 0.016
Identities = 33/144 (22%), Positives = 49/144 (34%), Gaps = 12/144 (8%)
Query: 235 RGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKP 294
+G+ PP + P SP P +P + P A++ P G+
Sbjct: 1077 KGAPTPPAATP--------PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 295 PSSTP----GSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQ 350
P++TP G PP G P G A APT+P + G
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1188
Query: 351 TLPRSSLSAFPAQPPVEELGQEQP 374
P+ + + A PP + G P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATP 1212
Score = 36.2 bits (82), Expect = 0.062
Identities = 43/158 (27%), Positives = 59/158 (37%), Gaps = 11/158 (6%)
Query: 255 SPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLS 314
+P A + P P+ + P S PP+ TP + P P +
Sbjct: 1543 APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP 1602
Query: 315 PQQQVQPSGSPARSLHSQAPTSPRPSLGPST---VGAPQTLP--RSSLSAFPAQPP--VE 367
P S SP + A T P P GP+T G P + P SSL P P
Sbjct: 1603 P---AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659
Query: 368 ELGQEQPQAVALLVSSKPKSAVPLVHVKET-VSKPYVT 404
++G PQA L + K +A+ V V S P +T
Sbjct: 1660 KMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
Score = 35.4 bits (80), Expect = 0.11
Identities = 43/200 (21%), Positives = 73/200 (36%), Gaps = 27/200 (13%)
Query: 237 SHGP--PVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKP 294
SH P P++ P ES S P++ P S +S + PPVS P P
Sbjct: 1755 SHSPKGPLAPP--------ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP 1806
Query: 295 -PSSTPGSSLPTPPPGLSPLSPQQQVQPS----------------GSPARSLHSQAPTSP 337
P+ P PGL SP + + P+ G P +S+ PT
Sbjct: 1807 VPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPK 1866
Query: 338 RPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKET 397
+ T A Q + +++ + E + + + Q + + + A +E
Sbjct: 1867 SAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEP 1926
Query: 398 VSKPYVTESPAEDSNWVNKV 417
VSK + S + ++K+
Sbjct: 1927 VSKAKQSRSEKKARKAMSKL 1946
Score = 34.3 bits (77), Expect = 0.24
Identities = 48/197 (24%), Positives = 73/197 (37%), Gaps = 28/197 (14%)
Query: 257 VSAPVSPLEQPPAQP--LASSTPLSLSG--------MPPVSFPAVHKPPSSTPGSSLPTP 306
V A L QP A+ L S+ LS++ +PP PA + P S + P P
Sbjct: 9 VPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFP 68
Query: 307 PPGLSPLSPQQQVQPSGSPARSLH-SQAPTSPR-------PSLGPSTVGAPQTLPRSSLS 358
P +P + P S +L AP +P P + P+ + + +L
Sbjct: 69 SPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLK 128
Query: 359 AFPAQPPVEELGQEQPQAVAL-------LVSSKPKSAVPLVHVKETVSKPYVTESPAEDS 411
P+ L P +V L++S P AV T+S P +P+E
Sbjct: 129 GTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPI---APSEPK 185
Query: 412 NWVNKVFKKNKQKTSGT 428
+NKV + GT
Sbjct: 186 TNLNKVPSEVVPNPKGT 202
Score = 34.3 bits (77), Expect = 0.24
Identities = 53/203 (26%), Positives = 83/203 (40%), Gaps = 56/203 (27%)
Query: 239 GPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST 298
GPP+S L SP+ AP L+ P+ SS PL+L + P S V K +
Sbjct: 108 GPPISPAALALA----SPMIAPT--LKGTPS----SSAPLALVALAPHS---VQKSSAFP 154
Query: 299 PGSSLPTPPPGL------------SPLSPQQQ------------VQPSGSPA-RSLHSQA 333
P +L T PP + +P++P + P G+P+ + S
Sbjct: 155 P--NLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTV 212
Query: 334 P---TSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEE-------LGQEQPQAVALLVSS 383
P +P S+ PQT P ++L+ A P V++ + + P +++L
Sbjct: 213 PYHCVTPMASIQSGVASLPQTTPTTTLAI--ASPQVKDTTISSVLISPQNPGSLSLKGPV 270
Query: 384 KPKSAVPLVHVKETVSKPYVTES 406
P +A+ L T S P VT S
Sbjct: 271 SPPAALSL----STQSLPVVTSS 289
Score = 33.1 bits (74), Expect = 0.52
Identities = 50/187 (26%), Positives = 74/187 (39%), Gaps = 27/187 (14%)
Query: 241 PVSQPVQ-----TLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPP 295
P + PV+ TL + + PV+P Q PLA+ L L+ P S P+ PP
Sbjct: 685 PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT---LVLAPEIPKSVPSPSLPP 741
Query: 296 SST-PGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSL-----GPSTVG-- 347
+ T PG+ S L+P P P + A S + +L PS +G
Sbjct: 742 AGTPPGTKKVDGISHTSALAPVAS-SPKECPTEDSGASATASSKGTLTYLADSPSPLGVS 800
Query: 348 -APQTL--PRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVT 404
+PQT P SA P P +G + S P++++ K++ P T
Sbjct: 801 VSPQTKRPPTKKGSAGPDTP----IGNLSSPVSPVEASFLPENSLSFQGSKDS---PATT 853
Query: 405 ESPAEDS 411
SP S
Sbjct: 854 HSPTPPS 860
Score = 31.2 bits (69), Expect = 2.0
Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 19/120 (15%)
Query: 252 TCESPVSAPVSPL------EQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTP------ 299
T SP AP P E+ PA P TP S PPV+ ++ P+S
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTS----PPVTPSSLKDSPTSPASVTCKM 1661
Query: 300 GSSLPTPPPGLSPL---SPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSS 356
G+++P GL + ++V + +P + APT P S+ +P P S
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPS 1721
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 51.2 bits (121), Expect = 2e-06
Identities = 58/217 (26%), Positives = 80/217 (36%), Gaps = 34/217 (15%)
Query: 215 QASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSA---------PVSPLE 265
QA + ++ P + +GSH P L SPV + P +
Sbjct: 793 QAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQ 852
Query: 266 QPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSP 325
QPPA + + P + P A+H PP T PTPP P QQVQPS
Sbjct: 853 QPPATTIPAPVPTPPAMPPGPQSQALHPPPRQT-----PTPPTTQLP----QQVQPSLPA 903
Query: 326 A----------RSLHSQAPTSPRPS--LGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQ 373
A RS S A + P P+ L P P + P S+ + PP +
Sbjct: 904 APSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVN 963
Query: 374 PQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAED 410
QA+A K S + K V +P ++ ED
Sbjct: 964 SQAIA----EKQPSQEVKMEAKMEVDQPEPADTQPED 996
Score = 39.3 bits (90), Expect = 0.007
Identities = 56/247 (22%), Positives = 87/247 (35%), Gaps = 30/247 (12%)
Query: 139 IARMTHALFP-PDLVILHDYYYRGYEDAVLYLRRLNAVYLNSSSKRVIFPRVEVYCQIEL 197
+ ++ A+FP PD L D R E+ V Y R++ S++ R + + +
Sbjct: 584 VHKLVQAIFPTPDPAALKD---RRMENLVAYARKVEGDMYESANNRAEY--YHLLAEKIY 638
Query: 198 ALGNECPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPV 257
+ E E+ + L+ + A P GP + QP + T P+
Sbjct: 639 KIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNP--------GPNMGQPQPGM--TSNGPL 688
Query: 258 SAPVSPLEQPPAQPLASSTPLS--------LSGMPPV----SFPAVHKPPSSTPGSSLPT 305
P P Q + TP S PP+ + P H + PG+
Sbjct: 689 PDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGAL--N 746
Query: 306 PPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPP 365
PP G P Q Q P SQ L PS+ AP + + S S+ P P
Sbjct: 747 PPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSP 806
Query: 366 VEELGQE 372
+ G +
Sbjct: 807 IMPPGSQ 813
Score = 34.7 bits (78), Expect = 0.18
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 11/79 (13%)
Query: 295 PSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARS-LHSQAPTSPR-PSLGPSTVG----- 347
PS TP + PT P G P +PQ QP+ P + +S P PR + GP + G
Sbjct: 1848 PSPTPAT--PTTPTGQQPTTPQTP-QPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQ 1904
Query: 348 -APQTLPRSSLSAFPAQPP 365
P T P+++ P PP
Sbjct: 1905 VTPPTPPQTAQPPLPGPPP 1923
Score = 34.3 bits (77), Expect = 0.24
Identities = 39/138 (28%), Positives = 56/138 (40%), Gaps = 22/138 (15%)
Query: 265 EQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGS 324
+ PP P+A P+ ++ P P+ H P P PP L QQ+Q SG
Sbjct: 1955 QMPPMTPMA---PMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQ-SGM 2010
Query: 325 PARSLHSQAP------TSPRPSLG--------PSTVG--APQTLPRS--SLSAFPAQPPV 366
P ++ S A +P+P LG P TV A Q L R+ S S+ Q V
Sbjct: 2011 PRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQV 2070
Query: 367 EELGQEQPQAVALLVSSK 384
+ PQ +A + +
Sbjct: 2071 LSILHANPQLLAAFIKQR 2088
Score = 33.5 bits (75), Expect = 0.40
Identities = 37/114 (32%), Positives = 48/114 (42%), Gaps = 14/114 (12%)
Query: 268 PAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQ--VQPSGSP 325
P+ PL LS+ P A K ++ +S P P PG P PQ Q +QP P
Sbjct: 2061 PSSPLQQQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPG-QPGMPQGQPGLQPPTMP 2119
Query: 326 A-RSLHSQ-APTSPRP-SLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQA 376
+ +HS A + P G G PQ P+ L QPP +G PQA
Sbjct: 2120 GQQGVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQL-----QPP---MGGMSPQA 2165
Score = 31.6 bits (70), Expect = 1.5
Identities = 44/170 (25%), Positives = 59/170 (34%), Gaps = 38/170 (22%)
Query: 255 SPVSA-PVSPLEQPPA-----QPLASSTPLSLSGMPPVSFPAVHKPPSS----------- 297
SP A P +P Q P QP + P + MPP P S
Sbjct: 1849 SPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPP 1908
Query: 298 TPGSSLPTPPPGLSPLSPQ--QQVQPSGSPARSL-----------HSQAPTSPRPSLG-- 342
TP + P PG P + + Q+Q + R + H P +P +G
Sbjct: 1909 TPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQHQMPPMTPMAPMGMN 1968
Query: 343 --PSTVGAPQTL-PRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAV 389
P T G L P + QPP + G QPQ L S P+ A+
Sbjct: 1969 PPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQ---LQSGMPRPAM 2015
>gi|52630419 sterol regulatory element binding transcription factor
1 isoform a [Homo sapiens]
Length = 1177
Score = 51.2 bits (121), Expect = 2e-06
Identities = 59/195 (30%), Positives = 76/195 (38%), Gaps = 16/195 (8%)
Query: 220 GATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLS 279
G T P P GS PP + +LE P +AP SPL P P TPL
Sbjct: 87 GGTDPAS---PDTSSPGSLSPPPATLSSSLEAFLSGPQAAP-SPLSPPQPAP----TPLK 138
Query: 280 LSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRP 339
+ P P S P S L TP P P + Q P+ +P + + P P
Sbjct: 139 MYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSFPAPAPPQFSSTPVLGYPSP 198
Query: 340 SLGPSTVGAP----QTLPRSSLSAFPAQPPVEELGQEQ---PQAVALLVSSKPKSAVPLV 392
G ST P Q LP L++ P PPV Q Q PQ + L V++ P +A
Sbjct: 199 PGGFSTGSPPGNTQQPLPGLPLASPPGVPPVSLHTQVQSVVPQQL-LTVTAAPTAAPVTT 257
Query: 393 HVKETVSKPYVTESP 407
V + + V P
Sbjct: 258 TVTSQIQQVPVLLQP 272
>gi|22547195 sterol regulatory element binding transcription factor
1 isoform b [Homo sapiens]
Length = 1147
Score = 51.2 bits (121), Expect = 2e-06
Identities = 59/195 (30%), Positives = 76/195 (38%), Gaps = 16/195 (8%)
Query: 220 GATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLS 279
G T P P GS PP + +LE P +AP SPL P P TPL
Sbjct: 57 GGTDPAS---PDTSSPGSLSPPPATLSSSLEAFLSGPQAAP-SPLSPPQPAP----TPLK 108
Query: 280 LSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRP 339
+ P P S P S L TP P P + Q P+ +P + + P P
Sbjct: 109 MYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSFPAPAPPQFSSTPVLGYPSP 168
Query: 340 SLGPSTVGAP----QTLPRSSLSAFPAQPPVEELGQEQ---PQAVALLVSSKPKSAVPLV 392
G ST P Q LP L++ P PPV Q Q PQ + L V++ P +A
Sbjct: 169 PGGFSTGSPPGNTQQPLPGLPLASPPGVPPVSLHTQVQSVVPQQL-LTVTAAPTAAPVTT 227
Query: 393 HVKETVSKPYVTESP 407
V + + V P
Sbjct: 228 TVTSQIQQVPVLLQP 242
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 51.2 bits (121), Expect = 2e-06
Identities = 48/150 (32%), Positives = 59/150 (39%), Gaps = 23/150 (15%)
Query: 258 SAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGL---SPLS 314
S+ VSP PPA PL S G P P PP P +P PPP + SP +
Sbjct: 292 SSVVSPSHPPPAPPLGSPP-----GPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGT 346
Query: 315 PQQQVQPSGSPARSL----------HSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQP 364
P PS P + PT P P L T GAP P P P
Sbjct: 347 PPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPP---PGPP 403
Query: 365 PVEELGQEQPQAV--ALLVSSKPKSAVPLV 392
P G + A+ L ++KPKS++P V
Sbjct: 404 PPPFTGADGQPAIPPPLSDTTKPKSSLPAV 433
Score = 35.4 bits (80), Expect = 0.11
Identities = 44/170 (25%), Positives = 61/170 (35%), Gaps = 51/170 (30%)
Query: 226 KEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTP---LSLSG 282
+E+V + G+ G P + Q C V A P PP Q ++S+P S
Sbjct: 210 QEFVESKEKLGTSGYPPTLVYQNGSIGCVENVDASSYP---PPPQSDSASSPSPSFSEDN 266
Query: 283 MPP----VSFPAVHK------------------PPSSTPGSSLPTPPPGLSPLSPQQQVQ 320
+PP S+P ++ PP + P S P P PG +P
Sbjct: 267 LPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAP-------- 318
Query: 321 PSGSPARSLHSQAPTSPRPSLG------PSTVGAPQTLPRSSLSAFPAQP 364
PA P P P +G P G+P T P S +FP P
Sbjct: 319 ---PPA------PPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHP 359
Score = 33.5 bits (75), Expect = 0.40
Identities = 33/105 (31%), Positives = 37/105 (35%), Gaps = 10/105 (9%)
Query: 230 PKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQ-PLASSTPLS-----LSGM 283
P G G PP S P F +AP P P A P PLS
Sbjct: 338 PVGFGSPGTPPPPSPP----SFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP 393
Query: 284 PPVSFPAVHKPPSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPARS 328
PP P PP T P PP LS + + P+ S ARS
Sbjct: 394 PPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARS 438
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 50.8 bits (120), Expect = 2e-06
Identities = 58/209 (27%), Positives = 79/209 (37%), Gaps = 23/209 (11%)
Query: 209 PSLRARQASLEGATQPHKEWVPKGDGRGSHGPPV--SQPVQTLEFTCESPV-----SAPV 261
PS+ AS + T P+ ++P+ S V S V TL SP +AP
Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLA-PVNSPAPQDTTAAPP 170
Query: 262 SPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST---PGSSLPTPPPGLSPLSPQQQ 318
+P PA P SS P + PP PPSS+ ++ P PP +P P
Sbjct: 171 TPSATTPAPPS-SSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229
Query: 319 VQP---SGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQ 375
P + P S + AP S S P T P T ++L A P E P
Sbjct: 230 APPETTAAPPTPSATTPAPLS--SSAPPETTAVPPTPSATTLDPSSASAPPETTA--APP 285
Query: 376 AVALLVSSKPKSAVPLVHVKETVSKPYVT 404
+ + P S P +ET + P T
Sbjct: 286 TPSATTPAPPSSPAP----QETTAAPITT 310
Score = 43.5 bits (101), Expect = 4e-04
Identities = 33/135 (24%), Positives = 50/135 (37%), Gaps = 10/135 (7%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST- 298
PP + P +AP +P PA PL+SS P + +PP P S++
Sbjct: 218 PPATTPAPPSSSAPPETTAAPPTPSATTPA-PLSSSAPPETTAVPPTPSATTLDPSSASA 276
Query: 299 --------PGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQ 350
P S TP P SP + P +P S + AP + S P+
Sbjct: 277 PPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTS 336
Query: 351 TLPRSSLSAFPAQPP 365
+++ + P P
Sbjct: 337 VTTQTTTTKQPTSAP 351
Score = 40.8 bits (94), Expect = 0.003
Identities = 40/161 (24%), Positives = 62/161 (38%), Gaps = 12/161 (7%)
Query: 255 SPVSAPVSPL-EQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTP---PPGL 310
SP + P P QPP P +S+ ++ + + P+V P +ST ++LP P
Sbjct: 77 SPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNA 136
Query: 311 SPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELG 370
+ +S ++ V S S A +P + P T A P SS + PP
Sbjct: 137 TTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSS-----SAPPETTAA 191
Query: 371 QEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDS 411
P A + P S+ P + P T +P S
Sbjct: 192 PPTPSAT---TQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229
Score = 38.5 bits (88), Expect = 0.012
Identities = 46/172 (26%), Positives = 62/172 (36%), Gaps = 24/172 (13%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST- 298
P + P +AP +P A P +SS P + PP PPSS+
Sbjct: 172 PSATTPAPPSSSAPPETTAAPPTPSATTQAPP-SSSAPPETTAAPPTPPATTPAPPSSSA 230
Query: 299 --------PGSSLPTPPPGLSPLSPQQQVQPSGSP-ARSLHSQAPTSPRPSLGPSTVGAP 349
P S TP P LS +P + +P A +L + ++P P T AP
Sbjct: 231 PPETTAAPPTPSATTPAP-LSSSAPPETTAVPPTPSATTLDPSSASAP-----PETTAAP 284
Query: 350 QTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKP 401
T SA PP QE A +S P + P ET + P
Sbjct: 285 PT-----PSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP--DTSETSAAP 329
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 50.8 bits (120), Expect = 2e-06
Identities = 58/209 (27%), Positives = 79/209 (37%), Gaps = 23/209 (11%)
Query: 209 PSLRARQASLEGATQPHKEWVPKGDGRGSHGPPV--SQPVQTLEFTCESPV-----SAPV 261
PS+ AS + T P+ ++P+ S V S V TL SP +AP
Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLA-PVNSPAPQDTTAAPP 170
Query: 262 SPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST---PGSSLPTPPPGLSPLSPQQQ 318
+P PA P SS P + PP PPSS+ ++ P PP +P P
Sbjct: 171 TPSATTPAPPS-SSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229
Query: 319 VQP---SGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQ 375
P + P S + AP S S P T P T ++L A P E P
Sbjct: 230 APPETTAAPPTPSATTPAPLS--SSAPPETTAVPPTPSATTLDPSSASAPPETTA--APP 285
Query: 376 AVALLVSSKPKSAVPLVHVKETVSKPYVT 404
+ + P S P +ET + P T
Sbjct: 286 TPSATTPAPPSSPAP----QETTAAPITT 310
Score = 43.5 bits (101), Expect = 4e-04
Identities = 33/135 (24%), Positives = 50/135 (37%), Gaps = 10/135 (7%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST- 298
PP + P +AP +P PA PL+SS P + +PP P S++
Sbjct: 218 PPATTPAPPSSSAPPETTAAPPTPSATTPA-PLSSSAPPETTAVPPTPSATTLDPSSASA 276
Query: 299 --------PGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQ 350
P S TP P SP + P +P S + AP + S P+
Sbjct: 277 PPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTS 336
Query: 351 TLPRSSLSAFPAQPP 365
+++ + P P
Sbjct: 337 VTTQTTTTKQPTSAP 351
Score = 40.8 bits (94), Expect = 0.003
Identities = 40/161 (24%), Positives = 62/161 (38%), Gaps = 12/161 (7%)
Query: 255 SPVSAPVSPL-EQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTP---PPGL 310
SP + P P QPP P +S+ ++ + + P+V P +ST ++LP P
Sbjct: 77 SPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNA 136
Query: 311 SPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELG 370
+ +S ++ V S S A +P + P T A P SS + PP
Sbjct: 137 TTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSS-----SAPPETTAA 191
Query: 371 QEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDS 411
P A + P S+ P + P T +P S
Sbjct: 192 PPTPSAT---TQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229
Score = 38.5 bits (88), Expect = 0.012
Identities = 46/172 (26%), Positives = 62/172 (36%), Gaps = 24/172 (13%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST- 298
P + P +AP +P A P +SS P + PP PPSS+
Sbjct: 172 PSATTPAPPSSSAPPETTAAPPTPSATTQAPP-SSSAPPETTAAPPTPPATTPAPPSSSA 230
Query: 299 --------PGSSLPTPPPGLSPLSPQQQVQPSGSP-ARSLHSQAPTSPRPSLGPSTVGAP 349
P S TP P LS +P + +P A +L + ++P P T AP
Sbjct: 231 PPETTAAPPTPSATTPAP-LSSSAPPETTAVPPTPSATTLDPSSASAP-----PETTAAP 284
Query: 350 QTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKP 401
T SA PP QE A +S P + P ET + P
Sbjct: 285 PT-----PSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP--DTSETSAAP 329
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 50.8 bits (120), Expect = 2e-06
Identities = 58/209 (27%), Positives = 79/209 (37%), Gaps = 23/209 (11%)
Query: 209 PSLRARQASLEGATQPHKEWVPKGDGRGSHGPPV--SQPVQTLEFTCESPV-----SAPV 261
PS+ AS + T P+ ++P+ S V S V TL SP +AP
Sbjct: 112 PSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLA-PVNSPAPQDTTAAPP 170
Query: 262 SPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST---PGSSLPTPPPGLSPLSPQQQ 318
+P PA P SS P + PP PPSS+ ++ P PP +P P
Sbjct: 171 TPSATTPAPPS-SSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229
Query: 319 VQP---SGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELGQEQPQ 375
P + P S + AP S S P T P T ++L A P E P
Sbjct: 230 APPETTAAPPTPSATTPAPLS--SSAPPETTAVPPTPSATTLDPSSASAPPETTA--APP 285
Query: 376 AVALLVSSKPKSAVPLVHVKETVSKPYVT 404
+ + P S P +ET + P T
Sbjct: 286 TPSATTPAPPSSPAP----QETTAAPITT 310
Score = 43.5 bits (101), Expect = 4e-04
Identities = 33/135 (24%), Positives = 50/135 (37%), Gaps = 10/135 (7%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST- 298
PP + P +AP +P PA PL+SS P + +PP P S++
Sbjct: 218 PPATTPAPPSSSAPPETTAAPPTPSATTPA-PLSSSAPPETTAVPPTPSATTLDPSSASA 276
Query: 299 --------PGSSLPTPPPGLSPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQ 350
P S TP P SP + P +P S + AP + S P+
Sbjct: 277 PPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTS 336
Query: 351 TLPRSSLSAFPAQPP 365
+++ + P P
Sbjct: 337 VTTQTTTTKQPTSAP 351
Score = 40.8 bits (94), Expect = 0.003
Identities = 40/161 (24%), Positives = 62/161 (38%), Gaps = 12/161 (7%)
Query: 255 SPVSAPVSPL-EQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTP---PPGL 310
SP + P P QPP P +S+ ++ + + P+V P +ST ++LP P
Sbjct: 77 SPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNA 136
Query: 311 SPLSPQQQVQPSGSPARSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPVEELG 370
+ +S ++ V S S A +P + P T A P SS + PP
Sbjct: 137 TTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSS-----SAPPETTAA 191
Query: 371 QEQPQAVALLVSSKPKSAVPLVHVKETVSKPYVTESPAEDS 411
P A + P S+ P + P T +P S
Sbjct: 192 PPTPSAT---TQAPPSSSAPPETTAAPPTPPATTPAPPSSS 229
Score = 38.5 bits (88), Expect = 0.012
Identities = 46/172 (26%), Positives = 62/172 (36%), Gaps = 24/172 (13%)
Query: 240 PPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSST- 298
P + P +AP +P A P +SS P + PP PPSS+
Sbjct: 172 PSATTPAPPSSSAPPETTAAPPTPSATTQAPP-SSSAPPETTAAPPTPPATTPAPPSSSA 230
Query: 299 --------PGSSLPTPPPGLSPLSPQQQVQPSGSP-ARSLHSQAPTSPRPSLGPSTVGAP 349
P S TP P LS +P + +P A +L + ++P P T AP
Sbjct: 231 PPETTAAPPTPSATTPAP-LSSSAPPETTAVPPTPSATTLDPSSASAP-----PETTAAP 284
Query: 350 QTLPRSSLSAFPAQPPVEELGQEQPQAVALLVSSKPKSAVPLVHVKETVSKP 401
T SA PP QE A +S P + P ET + P
Sbjct: 285 PT-----PSATTPAPPSSPAPQETTAAPITTPNSSPTTLAP--DTSETSAAP 329
>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
sapiens]
Length = 834
Score = 50.4 bits (119), Expect = 3e-06
Identities = 55/209 (26%), Positives = 79/209 (37%), Gaps = 21/209 (10%)
Query: 214 RQASLEGATQPHKEWVPKGDGRGSHGPPVSQPVQTLEFTCESPVSAPVSPLEQPPAQPLA 273
++ASL+ Q ++ + PP++QP FT P +AP S PP LA
Sbjct: 124 KKASLQWFNQALEDKSDAASNSVTETPPITQP----SFTFTLPAAAPAS----PPTSLLA 175
Query: 274 SSTPLSLSGMPPVSFPAVHKP------PSSTPGSSLPTPPPGLSPLSPQQQVQPSGSPAR 327
ST L + + P P ++T S P P L PL Q P P+
Sbjct: 176 PSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSP 235
Query: 328 SLHSQAPTS-----PRPSLGPST-VGAPQTLPRSSLSAFPAQPPVEELGQEQPQAVALLV 381
S S PT+ P PS+ P+T AP TL ++ + P +Q
Sbjct: 236 SFDSNPPTTLLGLIPAPSMVPATDTKAPPTL-QAETTTKPQATSAPSPAPKQSFLFGTQN 294
Query: 382 SSKPKSAVPLVHVKETVSKPYVTESPAED 410
+S A P + KP T P +
Sbjct: 295 TSPSSPAAPAASSASPMFKPIFTAPPKSE 323
Score = 35.4 bits (80), Expect = 0.11
Identities = 43/180 (23%), Positives = 59/180 (32%), Gaps = 34/180 (18%)
Query: 203 CPERSQPSLRARQASLEGATQPHKEWVPKGDGRGSHGPPV--------SQPVQTLEFTCE 254
CPE A A+ E + P + G GPP S P TL
Sbjct: 197 CPES------AGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLGLIP 250
Query: 255 SPVSAPVSPLEQPPAQPLASSTPLSLSGMPPVSFPAVHKPPSSTPGSSLPTPPPGLSPLS 314
+P P + + PP ++T P PS P S SP S
Sbjct: 251 APSMVPATDTKAPPTLQAETTTK-----------PQATSAPSPAPKQSFLFGTQNTSPSS 299
Query: 315 PQQQVQPSGSPA--------RSLHSQAPTSPRPSLGPSTVGAPQTLPRSSLSAFPAQPPV 366
P S SP + PT P PS+ +T + +LP ++ + P PV
Sbjct: 300 PAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVS-ATAPSSSSLPTTTSTTAPTFQPV 358
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,117,045
Number of Sequences: 37866
Number of extensions: 1391571
Number of successful extensions: 18222
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 355
Number of HSP's successfully gapped in prelim test: 1665
Number of HSP's that attempted gapping in prelim test: 9184
Number of HSP's gapped (non-prelim): 6368
length of query: 446
length of database: 18,247,518
effective HSP length: 105
effective length of query: 341
effective length of database: 14,271,588
effective search space: 4866611508
effective search space used: 4866611508
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.