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Search of human proteins with 224465235
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224465235 euchromatic histone-lysine N-methyltransferase 1
isoform 2 [Homo sapiens]
(808 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224465235 euchromatic histone-lysine N-methyltransferase 1 is... 1625 0.0
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 1592 0.0
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 384 e-106
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 352 8e-97
gi|31543091 MAK16 homolog [Homo sapiens] 54 8e-07
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 50 1e-05
gi|83700233 eukaryotic translation initiation factor 3, subunit ... 50 1e-05
gi|4503525 eukaryotic translation initiation factor 3, subunit C... 50 1e-05
gi|115529449 upstream binding transcription factor, RNA polymera... 49 1e-05
gi|115529451 upstream binding transcription factor, RNA polymera... 49 1e-05
gi|7657671 upstream binding transcription factor, RNA polymerase... 49 1e-05
gi|153791492 eukaryotic translation initiation factor 3, subunit... 48 3e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 48 3e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 48 3e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 46 1e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 46 2e-04
gi|56090620 NFKB activating protein-like [Homo sapiens] 46 2e-04
gi|168229156 NFKB activating protein [Homo sapiens] 45 3e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 45 3e-04
gi|55741677 SET domain containing 1A [Homo sapiens] 45 3e-04
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 45 4e-04
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 45 4e-04
gi|164419758 bromodomain containing 2 [Homo sapiens] 44 5e-04
gi|4826806 bromodomain containing 2 [Homo sapiens] 44 5e-04
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 44 5e-04
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 44 5e-04
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 44 5e-04
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 44 5e-04
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 44 5e-04
gi|55956788 nucleolin [Homo sapiens] 44 6e-04
>gi|224465235 euchromatic histone-lysine N-methyltransferase 1
isoform 2 [Homo sapiens]
Length = 808
Score = 1625 bits (4208), Expect = 0.0
Identities = 808/808 (100%), Positives = 808/808 (100%)
Query: 1 MAAADAEAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCEN 60
MAAADAEAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCEN
Sbjct: 1 MAAADAEAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCEN 60
Query: 61 SDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVI 120
SDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVI
Sbjct: 61 SDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVI 120
Query: 121 GSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLG 180
GSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLG
Sbjct: 121 GSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLG 180
Query: 181 EGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKN 240
EGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKN
Sbjct: 181 EGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKN 240
Query: 241 ISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVP 300
ISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVP
Sbjct: 241 ISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVP 300
Query: 301 KKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD 360
KKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD
Sbjct: 301 KKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD 360
Query: 361 GHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSES 420
GHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSES
Sbjct: 361 GHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSES 420
Query: 421 SIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYM 480
SIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYM
Sbjct: 421 SIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYM 480
Query: 481 EVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQEVPLCSCRMETPKSREITTLANNQC 540
EVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQEVPLCSCRMETPKSREITTLANNQC
Sbjct: 481 EVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQEVPLCSCRMETPKSREITTLANNQC 540
Query: 541 MATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNF 600
MATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNF
Sbjct: 541 MATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNF 600
Query: 601 MECQPESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKADTTSTVTPVPGQEKG 660
MECQPESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKADTTSTVTPVPGQEKG
Sbjct: 601 MECQPESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKADTTSTVTPVPGQEKG 660
Query: 661 SALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPAGLGRPTPGLSQGPGKETL 720
SALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPAGLGRPTPGLSQGPGKETL
Sbjct: 661 SALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPAGLGRPTPGLSQGPGKETL 720
Query: 721 ESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAA 780
ESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAA
Sbjct: 721 ESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAA 780
Query: 781 AEAGHVDICHMLVQFCRLGSPRSRGCLW 808
AEAGHVDICHMLVQFCRLGSPRSRGCLW
Sbjct: 781 AEAGHVDICHMLVQFCRLGSPRSRGCLW 808
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1
isoform 1 [Homo sapiens]
Length = 1298
Score = 1592 bits (4123), Expect = 0.0
Identities = 794/794 (100%), Positives = 794/794 (100%)
Query: 1 MAAADAEAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCEN 60
MAAADAEAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCEN
Sbjct: 1 MAAADAEAVPARGEPQQDCCVKTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCEN 60
Query: 61 SDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVI 120
SDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVI
Sbjct: 61 SDASSHANAAKHTQDSARVNPQDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVI 120
Query: 121 GSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLG 180
GSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLG
Sbjct: 121 GSNGYILNKPALQAQPLRTTSTLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLG 180
Query: 181 EGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKN 240
EGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKN
Sbjct: 181 EGSADTEDRKLPAPGADVKVHRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKN 240
Query: 241 ISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVP 300
ISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVP
Sbjct: 241 ISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVP 300
Query: 301 KKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD 360
KKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD
Sbjct: 301 KKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD 360
Query: 361 GHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSES 420
GHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSES
Sbjct: 361 GHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSES 420
Query: 421 SIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYM 480
SIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYM
Sbjct: 421 SIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYM 480
Query: 481 EVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQEVPLCSCRMETPKSREITTLANNQC 540
EVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQEVPLCSCRMETPKSREITTLANNQC
Sbjct: 481 EVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQEVPLCSCRMETPKSREITTLANNQC 540
Query: 541 MATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNF 600
MATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNF
Sbjct: 541 MATESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNF 600
Query: 601 MECQPESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKADTTSTVTPVPGQEKG 660
MECQPESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKADTTSTVTPVPGQEKG
Sbjct: 601 MECQPESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKADTTSTVTPVPGQEKG 660
Query: 661 SALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPAGLGRPTPGLSQGPGKETL 720
SALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPAGLGRPTPGLSQGPGKETL
Sbjct: 661 SALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPAGLGRPTPGLSQGPGKETL 720
Query: 721 ESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAA 780
ESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAA
Sbjct: 721 ESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAA 780
Query: 781 AEAGHVDICHMLVQ 794
AEAGHVDICHMLVQ
Sbjct: 781 AEAGHVDICHMLVQ 794
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 384 bits (985), Expect = e-106
Identities = 250/681 (36%), Positives = 348/681 (51%), Gaps = 115/681 (16%)
Query: 147 LPGHAAKTLPGGAGKG-----RTPSAFPQTPAAPPATLG-----------EGSADTEDRK 190
L GHA K+ P KG R + +PP+ +G+A
Sbjct: 108 LLGHATKSFPSSPSKGGSCPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAAAAGSEP 167
Query: 191 LPA---PGADVKVHRARKTMPKSVVGLHAA-SKDPREVREARDHKEPKEEINKNISDFGR 246
PA P KVHRARKTM K G K P E++ R + + K SD +
Sbjct: 168 PPATTSPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEIQHFR-MSDDVHSLGKVTSDLAK 226
Query: 247 QQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKV 306
++ L L + L RR G +L +
Sbjct: 227 RRKLNSGGGLSEELGS---------------------------ARRSGEVTLTKGDPGSL 259
Query: 307 LKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQ 366
+ TV+ G+ SL+ + S++ D D E+E
Sbjct: 260 EEWETVV--------------GDD----FSLYYDSYSVDERVDSDSKSEVEA-------- 293
Query: 367 AAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKF 426
+++ E + ++ + E EEE+E + E+EE G++SD S S +K
Sbjct: 294 ----------LTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKA- 342
Query: 427 LKRKGKTDSPWIKPARKRRRRS---RKKPSGALGSESYKSSAGSAEQTAPGDSTGYMEVS 483
K+K + DSPW+KP+RKRR+R K+P G G S+G +E YMEV
Sbjct: 343 -KKKWRKDSPWVKPSRKRRKREPPRAKEPRGVNGV----GSSGPSE---------YMEVP 388
Query: 484 LDSLDLRVKGILSSQAEGLANGPDVLETD-GLQEVPLCSCRMETPKSREITTLANNQCMA 542
L SL+L +G LS G++N LET+ G +E+PLCSCRME PK I+ A ++CMA
Sbjct: 389 LGSLELPSEGTLSPNHAGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMA 448
Query: 543 TESVDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFME 602
TESVD EL C +++K E MRPS++ L+VLCE HR RMVKH CCPGCGYFCTAG F+E
Sbjct: 449 TESVDGELSGCNAAILKRETMRPSSRVALMVLCETHRARMVKHHCCPGCGYFCTAGTFLE 508
Query: 603 CQPESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKAD----TTSTVTPVPGQE 658
C P+ ++HRFHK C S++N +CPHCGE++S+A+EVTI + D T P P
Sbjct: 509 CHPDFRVAHRFHKACVSQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAPAP-PP 567
Query: 659 KGSALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPA-----GLGRPTPGLSQ 713
+ GRADT+ SA + + + + D +GP+ G GL
Sbjct: 568 LSQDVPGRADTSQPSAR--MRGHGEPRRPPCDPLADTIDSSGPSLTLPNGGCLSAVGLPL 625
Query: 714 GPGKETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNK 773
GPG+E LE AL+ +SE+ KKLRFHP+QLY S +QGELQKV+LML+D +DPNF+ + Q+K
Sbjct: 626 GPGREALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSK 685
Query: 774 RSPLHAAAEAGHVDICHMLVQ 794
R+PLHAAA+ G V+ICH+L+Q
Sbjct: 686 RTPLHAAAQKGSVEICHVLLQ 706
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 352 bits (903), Expect = 8e-97
Identities = 232/678 (34%), Positives = 328/678 (48%), Gaps = 143/678 (21%)
Query: 147 LPGHAAKTLPGGAGKG-----RTPSAFPQTPAAPPATLG-----------EGSADTEDRK 190
L GHA K+ P KG R + +PP+ +G+A
Sbjct: 108 LLGHATKSFPSSPSKGGSCPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAAAAGSEP 167
Query: 191 LPA---PGADVKVHRARKTMPKSVVGLHAA-SKDPREVREARDHKEPKEEINKNISDFGR 246
PA P KVHRARKTM K G K P E++ R + + K SD +
Sbjct: 168 PPATTSPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEIQHFR-MSDDVHSLGKVTSDLAK 226
Query: 247 QQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKV 306
++ L L + L RR G +L +
Sbjct: 227 RRKLNSGGGLSEELGS---------------------------ARRSGEVTLTKGDPGSL 259
Query: 307 LKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQ 366
+ TV+ G+ SL+ + S++ D D E+E
Sbjct: 260 EEWETVV--------------GDD----FSLYYDSYSVDERVDSDSKSEVEA-------- 293
Query: 367 AAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKF 426
+++ E + ++ + E EEE+E + E+EE G++SD S S +K
Sbjct: 294 ----------LTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKA- 342
Query: 427 LKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYMEVSLDS 486
K+K + DSPW+KP+RKRR+R +
Sbjct: 343 -KKKWRKDSPWVKPSRKRRKREPPR----------------------------------- 366
Query: 487 LDLRVKGILSSQAEGLANGPDVLETD-GLQEVPLCSCRMETPKSREITTLANNQCMATES 545
+ + G++N LET+ G +E+PLCSCRME PK I+ A ++CMATES
Sbjct: 367 ---------AKEPRGVSNDTSSLETERGFEELPLCSCRMEAPKIDRISERAGHKCMATES 417
Query: 546 VDHELGRCTNSVVKYELMRPSNKAPLLVLCEDHRGRMVKHQCCPGCGYFCTAGNFMECQP 605
VD EL C +++K E MRPS++ L+VLCE HR RMVKH CCPGCGYFCTAG F+EC P
Sbjct: 418 VDGELSGCNAAILKRETMRPSSRVALMVLCETHRARMVKHHCCPGCGYFCTAGTFLECHP 477
Query: 606 ESSISHRFHKDCASRVNNASYCPHCGEESSKAKEVTIAKAD----TTSTVTPVPGQEKGS 661
+ ++HRFHK C S++N +CPHCGE++S+A+EVTI + D T P P
Sbjct: 478 DFRVAHRFHKACVSQLNGMVFCPHCGEDASEAQEVTIPRGDGVTPPAGTAAPAP-PPLSQ 536
Query: 662 ALEGRADTTTGSAAGPPLSEDDKLQGAASHVPEGFDPTGPA-----GLGRPTPGLSQGPG 716
+ GRADT+ SA + + + + D +GP+ G GL GPG
Sbjct: 537 DVPGRADTSQPSAR--MRGHGEPRRPPCDPLADTIDSSGPSLTLPNGGCLSAVGLPLGPG 594
Query: 717 KETLESALIALDSEKPKKLRFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSP 776
+E LE AL+ +SE+ KKLRFHP+QLY S +QGELQKV+LML+D +DPNF+ + Q+KR+P
Sbjct: 595 REALEKALVIQESERRKKLRFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTP 654
Query: 777 LHAAAEAGHVDICHMLVQ 794
LHAAA+ G V+ICH+L+Q
Sbjct: 655 LHAAAQKGSVEICHVLLQ 672
>gi|31543091 MAK16 homolog [Homo sapiens]
Length = 300
Score = 53.5 bits (127), Expect = 8e-07
Identities = 54/228 (23%), Positives = 101/228 (44%), Gaps = 34/228 (14%)
Query: 224 VREARDHKEPKEEINKNI---SDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFV 280
VR ++++++ E+I++N+ F R + F + Q L + + T K Q +P
Sbjct: 81 VRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIR--KLTLKRQRKLVP-- 136
Query: 281 LAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVN 340
L+ V R++KRR + + + K+ ++E K T+ D+ +H
Sbjct: 137 LSKKVERREKRREEKALIAAQLDNAIEKE--LLERLKQDTYG--------DIYNFPIHAF 186
Query: 341 GESLEM---DSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEE 397
++LE +SD D+EE ++DD + ED + +S+ + K+D S+E
Sbjct: 187 DKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDMDKLDASSDE 246
Query: 398 EQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRR 445
+Q+ + EEEE +K L K K P P +++R
Sbjct: 247 DQDGKSSSEEEE--------------EKALSAKHKGKMPLRGPLQRKR 280
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 49.7 bits (117), Expect = 1e-05
Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 12/115 (10%)
Query: 347 DSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSE----------ADRAQKMDGESE 396
DSD++ + E + AA +E S+ ++E + ADR K + E E
Sbjct: 215 DSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEE 274
Query: 397 EEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKK 451
EE+E + EEEEG DE S E+ I K+F K +G+ + P +KP R + +
Sbjct: 275 EEEEEEEDDEEEEGDDEGQKSREAPILKEF-KEEGE-EIPRVKPEEMMDERPKTR 327
Score = 42.7 bits (99), Expect = 0.001
Identities = 80/337 (23%), Positives = 131/337 (38%), Gaps = 75/337 (22%)
Query: 222 REVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTACLPFVL 281
R+V +AR H P+ GR ++ S +S +++ A++ S+ + P V
Sbjct: 612 RDVAQARTHANPR----------GRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVS 661
Query: 282 ---AAAVSRKKKRRMGTYSL---VPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGAS 335
+ + + K G VP+ + K+RT S + S+V ++ ++
Sbjct: 662 RDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERT------STSSSSVQARRLSQPESA 715
Query: 336 SLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGES 395
HV + L+ + E EE AE AA + S T + E++R E
Sbjct: 716 EKHVT-QRLQPERGSPKKCEAEE-----AEPPAATQPQTSETQTSHLPESERIHHTVEEK 769
Query: 396 EEEQ--------------------ESVDTGEEEEGGDESDLSSESSIKKKFLKRK----- 430
EE + V + EG E + ESS+ K F KRK
Sbjct: 770 EEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSF-KRKISVVS 828
Query: 431 -------GKTDSPWIKPARKRR-----RRSRKKPSGALGSESYKSSAGSAEQTAPGDSTG 478
G +D+ +P RKRR ++KKPS ++ +ES KS + A ++
Sbjct: 829 ATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAV- 887
Query: 479 YMEVSLDSLDLRVKGILSSQAEGLANGPDVLETDGLQ 515
V L + D R+ S+ E NG D GL+
Sbjct: 888 ---VDLHADDSRI-----SEDETERNGDDGTHDKGLK 916
Score = 33.5 bits (75), Expect = 0.81
Identities = 34/146 (23%), Positives = 65/146 (44%), Gaps = 14/146 (9%)
Query: 342 ESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESE---EE 398
E E + +EDD EE +D+G + +A ++ + E + + MD + +E
Sbjct: 273 EEEEEEEEEDDEEEEGDDEGQKSREAPIL--KEFKEEGEEIPRVKPEEMMDERPKTRSQE 330
Query: 399 QESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPW------IKPARKRRRRSRKKP 452
QE ++ G E + +S + ++ +++ KT SP IK ++ + +S+
Sbjct: 331 QEVLERGGRFTRSQEE--ARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPS 388
Query: 453 SGALGSESYKSS-AGSAEQTAPGDST 477
L + K+S EQTA + T
Sbjct: 389 PPRLTEDRKKASLVALPEQTASEEET 414
>gi|83700233 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/195 (24%), Positives = 77/195 (39%), Gaps = 22/195 (11%)
Query: 288 KKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMD 347
KKK + + K+ K E +H T + + N E E
Sbjct: 127 KKKMNKNNAKALSTLRQKIRKYNRDFE-----SHITSYKQNPEQSADEDAEKNEEDSEGS 181
Query: 348 SDEDDSEELEEDDGHGA----EQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVD 403
SDED E++DG A ++ + P+ +SR + M + D D E E+ E D
Sbjct: 182 SDED-----EDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDE----DSEDSEDDEDWD 232
Query: 404 TGEEEEGGD-ESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKK---PSGALGSE 459
TG D E + ++++ +FLK+ TD +KR +++KK S L E
Sbjct: 233 TGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEE 292
Query: 460 SYKSSAGSAEQTAPG 474
+ G E+ G
Sbjct: 293 EEDNEGGEWERVRGG 307
>gi|4503525 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/195 (24%), Positives = 77/195 (39%), Gaps = 22/195 (11%)
Query: 288 KKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMD 347
KKK + + K+ K E +H T + + N E E
Sbjct: 127 KKKMNKNNAKALSTLRQKIRKYNRDFE-----SHITSYKQNPEQSADEDAEKNEEDSEGS 181
Query: 348 SDEDDSEELEEDDGHGA----EQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVD 403
SDED E++DG A ++ + P+ +SR + M + D D E E+ E D
Sbjct: 182 SDED-----EDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDE----DSEDSEDDEDWD 232
Query: 404 TGEEEEGGD-ESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKK---PSGALGSE 459
TG D E + ++++ +FLK+ TD +KR +++KK S L E
Sbjct: 233 TGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEE 292
Query: 460 SYKSSAGSAEQTAPG 474
+ G E+ G
Sbjct: 293 EEDNEGGEWERVRGG 307
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 49.3 bits (116), Expect = 1e-05
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 16/102 (15%)
Query: 320 THSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSK 379
+ +T+ SK E + E E D D++D +E EEDD +G +ED S
Sbjct: 630 SRTTLQSKSESE----------EDDEEDEDDEDEDEEEEDDENGDS------SEDGGDSS 673
Query: 380 ESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESS 421
ES SE + + E ++E E D ++E+ +ES+ SS SS
Sbjct: 674 ESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSS 715
Score = 35.8 bits (81), Expect = 0.16
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
Query: 373 EDSRTSKESMSEADRAQKMDGESEEEQESVDTGE----EEEGGDESDLSSE 419
+ SRT+ +S SE++ + D + E+E E + E E+GGD S+ SSE
Sbjct: 628 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 678
Score = 30.8 bits (68), Expect = 5.3
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 5/77 (6%)
Query: 342 ESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQES 401
E E D + D S ED G +E ++ +ED ++E + D + D E E+ +
Sbjct: 655 EEEEDDENGDSS----EDGGDSSESSSEDESEDGDENEEDDEDEDDDED-DDEDEDNESE 709
Query: 402 VDTGEEEEGGDESDLSS 418
+ GD SD S
Sbjct: 710 GSSSSSSSSGDSSDSDS 726
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 49.3 bits (116), Expect = 1e-05
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 16/102 (15%)
Query: 320 THSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSK 379
+ +T+ SK E + E E D D++D +E EEDD +G +ED S
Sbjct: 630 SRTTLQSKSESE----------EDDEEDEDDEDEDEEEEDDENGDS------SEDGGDSS 673
Query: 380 ESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESS 421
ES SE + + E ++E E D ++E+ +ES+ SS SS
Sbjct: 674 ESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSS 715
Score = 35.8 bits (81), Expect = 0.16
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
Query: 373 EDSRTSKESMSEADRAQKMDGESEEEQESVDTGE----EEEGGDESDLSSE 419
+ SRT+ +S SE++ + D + E+E E + E E+GGD S+ SSE
Sbjct: 628 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 678
Score = 30.8 bits (68), Expect = 5.3
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 5/77 (6%)
Query: 342 ESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQES 401
E E D + D S ED G +E ++ +ED ++E + D + D E E+ +
Sbjct: 655 EEEEDDENGDSS----EDGGDSSESSSEDESEDGDENEEDDEDEDDDED-DDEDEDNESE 709
Query: 402 VDTGEEEEGGDESDLSS 418
+ GD SD S
Sbjct: 710 GSSSSSSSSGDSSDSDS 726
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 49.3 bits (116), Expect = 1e-05
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 16/102 (15%)
Query: 320 THSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSK 379
+ +T+ SK E + E E D D++D +E EEDD +G +ED S
Sbjct: 667 SRTTLQSKSESE----------EDDEEDEDDEDEDEEEEDDENGDS------SEDGGDSS 710
Query: 380 ESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESS 421
ES SE + + E ++E E D ++E+ +ES+ SS SS
Sbjct: 711 ESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSS 752
Score = 35.8 bits (81), Expect = 0.16
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 4/51 (7%)
Query: 373 EDSRTSKESMSEADRAQKMDGESEEEQESVDTGE----EEEGGDESDLSSE 419
+ SRT+ +S SE++ + D + E+E E + E E+GGD S+ SSE
Sbjct: 665 KSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSE 715
Score = 30.8 bits (68), Expect = 5.3
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 5/77 (6%)
Query: 342 ESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQES 401
E E D + D S ED G +E ++ +ED ++E + D + D E E+ +
Sbjct: 692 EEEEDDENGDSS----EDGGDSSESSSEDESEDGDENEEDDEDEDDDED-DDEDEDNESE 746
Query: 402 VDTGEEEEGGDESDLSS 418
+ GD SD S
Sbjct: 747 GSSSSSSSSGDSSDSDS 763
>gi|153791492 eukaryotic translation initiation factor 3, subunit
C-like [Homo sapiens]
Length = 914
Score = 48.1 bits (113), Expect = 3e-05
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 19/169 (11%)
Query: 288 KKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMD 347
KKK + + K+ K E +H T + + N E E
Sbjct: 127 KKKMNKNNAKALSTLRQKIRKYNRDFE-----SHITSYKQNPEQSADEDAEKNEEDSEGS 181
Query: 348 SDEDDSEELEEDDGHGA----EQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVD 403
SDED E++DG A ++ + P+ +SR + M + D D E E+ E D
Sbjct: 182 SDED-----EDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDE----DSEDSEDDEDWD 232
Query: 404 TGEEEEGGD-ESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKK 451
TG D E + ++++ +FLK+ TD +KR +++KK
Sbjct: 233 TGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKK 281
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 48.1 bits (113), Expect = 3e-05
Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 11/105 (10%)
Query: 334 ASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDG 393
A++ V E E + +E EE EED+G ++QA E+ + KE SE + ++ +G
Sbjct: 515 ATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA-----EEGGSEKEGSSEKEEGEQEEG 569
Query: 394 ESEEEQESVDTGEEEEGGDESDL--SSESSIKKKFLKRKGKTDSP 436
E+E E E GEE E +E + SE K+ L K + P
Sbjct: 570 ETEAEAE----GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 610
Score = 40.0 bits (92), Expect = 0.009
Identities = 82/397 (20%), Positives = 143/397 (36%), Gaps = 62/397 (15%)
Query: 22 KTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSARVNP 81
K E G+E DEG+ QA E E GS E + + +
Sbjct: 527 KEEEEGQEEEEEEDEGAKSDQAEE----GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 582
Query: 82 QDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQAQPLRTTS 141
++ E V E+ E A + + AD V+ KP P+
Sbjct: 583 KE---------EKKVEEKSEEVATKEELVADAKVE------------KPEKAKSPVP--- 618
Query: 142 TLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLGEGSADTEDR-KLPAPGADVKV 200
S + +P + + S P++P + E++ K P + V+
Sbjct: 619 --KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVE- 675
Query: 201 HRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSL 260
+A+ +PKS V +K EV + E KEE K + + +++ + + +
Sbjct: 676 EKAKSPVPKSPV---EEAKSKAEVGKG----EQKEEEEKEVKEAPKEEKVEKKEEKPKDV 728
Query: 261 PQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMF--KS 318
P+ + + K + + +V ++ K++ K L+Q E +
Sbjct: 729 PEKKKAESPVKEEAVAEVVTITKSVKVHLEKE-------TKEEGKPLQQEKEKEKAGGEG 781
Query: 319 ITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTS 378
+ KG K + VNG E++ E+ +E +E G G E+ T
Sbjct: 782 GSEEEGSDKGAKGSRKEDIAVNG---EVEGKEEVEQETKE-KGSGREEEKGVVTNGL--- 834
Query: 379 KESMSEADRAQKMDGESEEEQESVDTGEEE---EGGD 412
+S AD +K G+ EE+ V E+ EGGD
Sbjct: 835 --DLSPAD--EKKGGDKSEEKVVVTKTVEKITSEGGD 867
Score = 36.2 bits (82), Expect = 0.12
Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 11/145 (7%)
Query: 297 SLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDD---S 353
S + K K + K + + + I T + EK +L E L + E+ +
Sbjct: 434 SKIQKPKVEAPKLKVQHKFVEEIIEETK-VEDEKSEMEEALTAITEELAVSMKEEKKEAA 492
Query: 354 EELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQES---VDTGEEEEG 410
EE EE+ E+ AA + T+ E E ++ +G+ EEE+E + + EEG
Sbjct: 493 EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEE-DEGAKSDQAEEG 551
Query: 411 GDESDLSSESSIKKKFLKRKGKTDS 435
G E + SSE K++ + +G+T++
Sbjct: 552 GSEKEGSSE---KEEGEQEEGETEA 573
Score = 35.8 bits (81), Expect = 0.16
Identities = 76/414 (18%), Positives = 147/414 (35%), Gaps = 72/414 (17%)
Query: 28 EETPMAADEGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSARVNPQDGTNT 87
EE AA+E E +A E +AA + + + K ++ ++
Sbjct: 486 EEKKEAAEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 543
Query: 88 LTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQ--AQPLRTTSTLAS 145
+ AE G SE++ + K+ + + G + ++ ++ + T L +
Sbjct: 544 KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 603
Query: 146 SL----PGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLGEGSADTEDR-KLPAPGADVKV 200
P A +P + + S P++P + E++ K P P + V+
Sbjct: 604 DAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE- 662
Query: 201 HRARKTMPKSVVGLHAASKDPRE-VREARDHKE-----PKEEINKNISDFGRQQLLPPFP 254
+ + + KS V A S P+ V EA+ E KEE K + + +++ +
Sbjct: 663 EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE 722
Query: 255 SLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIE 314
+ +P+ KK +K+ V E
Sbjct: 723 EKPKDVPEK-------------------------------------KKAESPVKEEAVAE 745
Query: 315 MFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTED 374
+ +IT S +H+ E+ E +E E+ G G +
Sbjct: 746 VV-TITKSV------------KVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGA 792
Query: 375 SRTSKESMSEADRAQKMDGESEEEQESVDTG---EEEEGGDESDLSSESSIKKK 425
+ KE ++ +++G+ E EQE+ + G EEE+G + L + +KK
Sbjct: 793 KGSRKEDIAVNG---EVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKK 843
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 48.1 bits (113), Expect = 3e-05
Identities = 34/105 (32%), Positives = 52/105 (49%), Gaps = 11/105 (10%)
Query: 334 ASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDG 393
A++ V E E + +E EE EED+G ++QA E+ + KE SE + ++ +G
Sbjct: 139 ATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA-----EEGGSEKEGSSEKEEGEQEEG 193
Query: 394 ESEEEQESVDTGEEEEGGDESDL--SSESSIKKKFLKRKGKTDSP 436
E+E E E GEE E +E + SE K+ L K + P
Sbjct: 194 ETEAEAE----GEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 234
Score = 40.0 bits (92), Expect = 0.009
Identities = 82/397 (20%), Positives = 143/397 (36%), Gaps = 62/397 (15%)
Query: 22 KTELLGEETPMAADEGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSARVNP 81
K E G+E DEG+ QA E E GS E + + +
Sbjct: 151 KEEEEGQEEEEEEDEGAKSDQAEE----GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEA 206
Query: 82 QDGTNTLTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQAQPLRTTS 141
++ E V E+ E A + + AD V+ KP P+
Sbjct: 207 KE---------EKKVEEKSEEVATKEELVADAKVE------------KPEKAKSPVP--- 242
Query: 142 TLASSLPGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLGEGSADTEDR-KLPAPGADVKV 200
S + +P + + S P++P + E++ K P + V+
Sbjct: 243 --KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVE- 299
Query: 201 HRARKTMPKSVVGLHAASKDPREVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSL 260
+A+ +PKS V +K EV + E KEE K + + +++ + + +
Sbjct: 300 EKAKSPVPKSPV---EEAKSKAEVGKG----EQKEEEEKEVKEAPKEEKVEKKEEKPKDV 352
Query: 261 PQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMF--KS 318
P+ + + K + + +V ++ K++ K L+Q E +
Sbjct: 353 PEKKKAESPVKEEAVAEVVTITKSVKVHLEKE-------TKEEGKPLQQEKEKEKAGGEG 405
Query: 319 ITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTS 378
+ KG K + VNG E++ E+ +E +E G G E+ T
Sbjct: 406 GSEEEGSDKGAKGSRKEDIAVNG---EVEGKEEVEQETKE-KGSGREEEKGVVTNGL--- 458
Query: 379 KESMSEADRAQKMDGESEEEQESVDTGEEE---EGGD 412
+S AD +K G+ EE+ V E+ EGGD
Sbjct: 459 --DLSPAD--EKKGGDKSEEKVVVTKTVEKITSEGGD 491
Score = 36.2 bits (82), Expect = 0.12
Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 11/145 (7%)
Query: 297 SLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDD---S 353
S + K K + K + + + I T + EK +L E L + E+ +
Sbjct: 58 SKIQKPKVEAPKLKVQHKFVEEIIEETK-VEDEKSEMEEALTAITEELAVSMKEEKKEAA 116
Query: 354 EELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQES---VDTGEEEEG 410
EE EE+ E+ AA + T+ E E ++ +G+ EEE+E + + EEG
Sbjct: 117 EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEE-DEGAKSDQAEEG 175
Query: 411 GDESDLSSESSIKKKFLKRKGKTDS 435
G E + SSE K++ + +G+T++
Sbjct: 176 GSEKEGSSE---KEEGEQEEGETEA 197
Score = 35.8 bits (81), Expect = 0.16
Identities = 76/414 (18%), Positives = 147/414 (35%), Gaps = 72/414 (17%)
Query: 28 EETPMAADEGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSARVNPQDGTNT 87
EE AA+E E +A E +AA + + + K ++ ++
Sbjct: 110 EEKKEAAEEKEEEPEAEEEEVAA--KKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA 167
Query: 88 LTRIAENGVSERDSEAAKQNHVTADDFVQTSVIGSNGYILNKPALQ--AQPLRTTSTLAS 145
+ AE G SE++ + K+ + + G + ++ ++ + T L +
Sbjct: 168 KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227
Query: 146 SL----PGHAAKTLPGGAGKGRTPSAFPQTPAAPPATLGEGSADTEDR-KLPAPGADVKV 200
P A +P + + S P++P + E++ K P P + V+
Sbjct: 228 DAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE- 286
Query: 201 HRARKTMPKSVVGLHAASKDPRE-VREARDHKE-----PKEEINKNISDFGRQQLLPPFP 254
+ + + KS V A S P+ V EA+ E KEE K + + +++ +
Sbjct: 287 EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE 346
Query: 255 SLHQSLPQNQCYMATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIE 314
+ +P+ KK +K+ V E
Sbjct: 347 EKPKDVPEK-------------------------------------KKAESPVKEEAVAE 369
Query: 315 MFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTED 374
+ +IT S +H+ E+ E +E E+ G G +
Sbjct: 370 VV-TITKSV------------KVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGA 416
Query: 375 SRTSKESMSEADRAQKMDGESEEEQESVDTG---EEEEGGDESDLSSESSIKKK 425
+ KE ++ +++G+ E EQE+ + G EEE+G + L + +KK
Sbjct: 417 KGSRKEDIAVNG---EVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKK 467
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 46.2 bits (108), Expect = 1e-04
Identities = 30/95 (31%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Query: 327 KGEKDLGASSLHVNGESLEMDSDEDDSE-ELEEDDGHGAEQAAAFPTEDSRTSKESMSEA 385
+GE++ G GE E + +E++ E E E+ +G G E+ + E+ E E
Sbjct: 911 EGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEG 970
Query: 386 DRAQKMDGESE-EEQESVDTGEEEEGGDESDLSSE 419
+ + +GE E EE+E GEEEEG +E + E
Sbjct: 971 E-GEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004
Score = 43.9 bits (102), Expect = 6e-04
Identities = 28/95 (29%), Positives = 47/95 (49%), Gaps = 6/95 (6%)
Query: 341 GESLEMDSDEDDSE-ELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQ 399
GE E + +E++ E E EE +G G E+ E+ +E ++ +GE E E+
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEG-----EEGEGEEEGEEGEGEGEEEEGEGEGEE 889
Query: 400 ESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTD 434
E GEEEEG E + E +++ + KG+ +
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEE 924
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 19/145 (13%)
Query: 327 KGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEAD 386
KGEKD G + GE + + + EE ++ DG EQ +E + +
Sbjct: 676 KGEKDKGRGEMERPGEG---EKELAEKEEWKKRDGEEQEQ----------KEREQGHQKE 722
Query: 387 RAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRR 446
R Q+M+ EEE GEEEEG E + E K++ + + + + RK+
Sbjct: 723 RNQEMEEGGEEEH---GEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779
Query: 447 RSRKKPSGALGSESYKSSAGSAEQT 471
R+ K+ G E G E+T
Sbjct: 780 RAGKEEK---GEEEGDQGEGEEEET 801
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 4/96 (4%)
Query: 327 KGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEAD 386
+GE++ G GE E + +E + E EE +G G E+ E+ E E +
Sbjct: 877 EGEEEEGEGEGEEEGEG-EGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE 935
Query: 387 RAQKM--DGESE-EEQESVDTGEEEEGGDESDLSSE 419
+ DGE E EE+E GEEEEG E + E
Sbjct: 936 EGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGE 971
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/138 (24%), Positives = 57/138 (41%), Gaps = 18/138 (13%)
Query: 342 ESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEE--- 398
E E + +E+ E EE +G G E+ E+ +E E + ++ +GE EEE
Sbjct: 960 EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEG 1019
Query: 399 --------QESVDTGEEEEG---GDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRR 447
+E GEEEEG G+E + E ++ + + + + + + + R
Sbjct: 1020 EVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENER 1079
Query: 448 ----SRKKPSGALGSESY 461
KK S GS Y
Sbjct: 1080 QDGEEYKKVSKIKGSVKY 1097
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/87 (29%), Positives = 36/87 (41%)
Query: 329 EKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRA 388
E+ G GE E + + EE EE +G G E+ ED E
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEG 957
Query: 389 QKMDGESEEEQESVDTGEEEEGGDESD 415
++ +GE E E+E GEE EG E +
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Score = 40.8 bits (94), Expect = 0.005
Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 13/93 (13%)
Query: 329 EKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKE-SMSEADR 387
E + G H GE +E D EE EE +G G E+ E R +E + +R
Sbjct: 726 EMEEGGEEEHGEGEE-----EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780
Query: 388 AQKMD-GESE------EEQESVDTGEEEEGGDE 413
A K + GE E EE+E+ GEE+E G E
Sbjct: 781 AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813
Score = 39.7 bits (91), Expect = 0.011
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 323 TVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESM 382
T G EK+ G E E++ + + EE EE++G G E+ E+ +E
Sbjct: 801 TEGRGEEKEEGGEV-----EGGEVEEGKGEREE-EEEEGEGEEEEGEGEEEEGEGEEEEG 854
Query: 383 SEADRAQKMDGESEEE-QESVDTGEEEEGGDESDLSSE 419
+ +GE EEE +E GEEEEG E + E
Sbjct: 855 EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGE 892
Score = 39.7 bits (91), Expect = 0.011
Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 9/115 (7%)
Query: 327 KGEKDLGASSLHVNGESLEMDSDEDDSEE-------LEEDDGHGAEQAAAFPTEDSRTSK 379
+GE++ G GE E E + EE +E ++G G + E K
Sbjct: 989 EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREK 1048
Query: 380 ESMSEADRAQKMDGESEEEQESVDTGEEE-EGGDESDLSSESSIKKKFLKRKGKT 433
E E +R + + E EEE + +TGEEE E D + S IK K KT
Sbjct: 1049 EGEGEENRRNR-EEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKT 1102
Score = 38.9 bits (89), Expect = 0.019
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 12/99 (12%)
Query: 327 KGEKDLGASSLHVNGESLEMDSDEDDSE---ELEEDDGHGAEQAAAFPTEDSRTSKESMS 383
+GE++ G GE E + +E++ E E E ++G G E+ E E
Sbjct: 834 EGEEEEG------EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG 887
Query: 384 EAD---RAQKMDGESEEEQESVDTGEEEEGGDESDLSSE 419
E + ++ +GE E E+E GEEEEG + + E
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE 926
Score = 38.9 bits (89), Expect = 0.019
Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 15/162 (9%)
Query: 325 GSKGEKDLGASSLHVNGESLEMDSDEDDSE---ELEEDDGHGAEQAAAFPTEDSRTSKES 381
G +GE + GE E + +E++ E E EE +G G E+ E +E
Sbjct: 925 GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Query: 382 MSEADRAQKMDGESEE-EQESVDTGE-EEEGGDESDLSSESSIKKKFLKRKGKTDSPWIK 439
E +GE EE E+E + GE EEEG E + E ++ + +G+ + +
Sbjct: 985 EGEG------EGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE 1038
Query: 440 PARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYME 481
+ R ++ G E+ ++ E+ TG E
Sbjct: 1039 GEEEGEEREKE----GEGEENRRNREEEEEEEGKYQETGEEE 1076
Score = 37.7 bits (86), Expect = 0.043
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 327 KGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEAD 386
+GE+ G E + +++ E E D G G E+ TE KE E +
Sbjct: 760 EGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEE----TEGRGEEKEEGGEVE 815
Query: 387 RAQKMDGESE-EEQESVDTGEEEEGGDESD 415
+ +G+ E EE+E GEEEEG E +
Sbjct: 816 GGEVEEGKGEREEEEEEGEGEEEEGEGEEE 845
Score = 37.4 bits (85), Expect = 0.056
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 9/83 (10%)
Query: 342 ESLEMDSDEDDSEELEEDDGHGAE-----QAAAFPTEDSRTSKESMSEADRAQKMDGESE 396
E E + D+ + EE EE +G G E + E+ + +E E ++ +GE E
Sbjct: 785 EKGEEEGDQGEGEE-EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGE 843
Query: 397 EEQESVDTGEEEEGGDESDLSSE 419
EE+ GEEEEG + + E
Sbjct: 844 EEE---GEGEEEEGEGKGEEEGE 863
Score = 32.0 bits (71), Expect = 2.4
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 8/59 (13%)
Query: 22 KTELLGEETPMAAD--EGSAEKQAGEAHMAADGETNGSCENSDASSHANAAKHTQDSAR 78
KTE+L ++ A+ EG A K GEA +G +G+CE ++ A+H QD R
Sbjct: 622 KTEILSDDLTDKAEVSEGKA-KSVGEAEDGPEGRGDGTCEEG-----SSGAEHWQDEER 674
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 2e-04
Identities = 45/164 (27%), Positives = 67/164 (40%), Gaps = 28/164 (17%)
Query: 321 HSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKE 380
H T GS G D ++ E +E D +ED EE+EED ED ++
Sbjct: 183 HET-GSSGSSDEQGNNTENEEEGVEEDVEED--EEVEED-----------AEEDEEVDED 228
Query: 381 SMSEADRAQKMDGESEEEQESVDTGE---EEEGGD---ESDLSSESSIKKKFLKRKGKTD 434
E + ++ + E EEE+E + E +EEG D S+ S S F ++
Sbjct: 229 GEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSG 288
Query: 435 SPWIKPARKRRRRSRKK--------PSGALGSESYKSSAGSAEQ 470
S K++ R R + SG+ SESY S E+
Sbjct: 289 SGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEK 332
Score = 35.0 bits (79), Expect = 0.28
Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 11/115 (9%)
Query: 301 KKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD 360
K T +R +E+ + + S+ SK E VN E D + S +E
Sbjct: 145 KSPTPDGSERIGLEVDRRASRSSQSSKEE---------VNSEEYGSDHETGSSGSSDEQ- 194
Query: 361 GHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESD 415
G+ E ED +E +A+ +++D + EEE+E + EEEE +E +
Sbjct: 195 GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEE-EEEEEEEEEEEEE 248
Score = 30.4 bits (67), Expect = 6.9
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 2/75 (2%)
Query: 345 EMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDT 404
E++S+E S+ G EQ TE+ E E D + D E +EE +
Sbjct: 173 EVNSEEYGSDHETGSSGSSDEQGNN--TENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230
Query: 405 GEEEEGGDESDLSSE 419
EEEE +E + E
Sbjct: 231 EEEEEEEEEEEEEEE 245
>gi|56090620 NFKB activating protein-like [Homo sapiens]
Length = 402
Score = 45.8 bits (107), Expect = 2e-04
Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 12/126 (9%)
Query: 345 EMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDT 404
++DSDE E EE+ H ++ +E+ R K S S + +K + ++ D+
Sbjct: 145 QLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDS 204
Query: 405 GEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSS 464
+ ESD +S+S KK +K K K +K++ +++KK + ES SS
Sbjct: 205 ----DSNSESDTNSDSDDDKKRVKAK--------KKKKKKKHKTKKKKNKKTKKESSDSS 252
Query: 465 AGSAEQ 470
+E+
Sbjct: 253 CKDSEE 258
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 45.1 bits (105), Expect = 3e-04
Identities = 60/265 (22%), Positives = 107/265 (40%), Gaps = 38/265 (14%)
Query: 216 AASKDPREVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSLPQNQCYMATTKSQTA 275
++SK P+ + AR + + + R L L Q +NQ Y + ++S++
Sbjct: 23 SSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQG-SRNQSYRSRSRSRSR 81
Query: 276 -------CLPFVLAAA------VSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHS 322
+PF A++ SR SL+ K++ + L+Q+ + E
Sbjct: 82 ERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSE------RE 135
Query: 323 TVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESM 382
+G G ++ S ++ E DSDE E EE +A +E+ + K S
Sbjct: 136 RIGELGAPEVWGLS----PKNPEPDSDEHTPVEDEEPK---KSTTSASTSEEEKKKKSSR 188
Query: 383 SEA-------DRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDS 435
S+ ++ K + E D+ E + DE + KKK K+K ++
Sbjct: 189 SKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSK- 247
Query: 436 PWIKPARKRRRRSRKKPSGALGSES 460
K +KR ++SRK+ S + ES
Sbjct: 248 ---KYKKKRSKKSRKESSDSSSKES 269
Score = 30.4 bits (67), Expect = 6.9
Identities = 31/171 (18%), Positives = 71/171 (41%), Gaps = 21/171 (12%)
Query: 296 YSLVPKKKTKVLKQRTVIE---MFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDD 352
+ L PK + T +E KS T ++ + +K + S + + + S +
Sbjct: 146 WGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRK 205
Query: 353 SEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGD 412
++ ED ++ +E + +++ A +A+K + + + + ++
Sbjct: 206 HKKYSEDSDSDSD------SETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRK 259
Query: 413 ESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESYKS 463
ES SS +++FL ++PW + R ++PS +G E+ K+
Sbjct: 260 ESSDSSSKESQEEFL------ENPW------KDRTKAEEPSDLIGPEAPKT 298
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 45.1 bits (105), Expect = 3e-04
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 10/115 (8%)
Query: 345 EMDSDEDDSEELEEDDGHGAEQAAAF--------PTEDSRTSKESMSEADRAQKMDGESE 396
E + +++EE EE +G E+ T+++ KE E + ++ + +
Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70
Query: 397 EEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKK 451
EE+E + EEEE E + E +KK KR+ K + + +KRRR+++KK
Sbjct: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE--EKKKKRRRKTKKK 123
Score = 32.0 bits (71), Expect = 2.4
Identities = 19/65 (29%), Positives = 30/65 (46%)
Query: 387 RAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRRR 446
+ +K + E EE E + EE+EG + + K+K K K + K+R+
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 447 RSRKK 451
R RKK
Sbjct: 64 RKRKK 68
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 45.1 bits (105), Expect = 3e-04
Identities = 44/149 (29%), Positives = 63/149 (42%), Gaps = 22/149 (14%)
Query: 343 SLEMDSDEDDSEELEE--------------DDGHGAEQ-----AAAFPTEDSRTSKESMS 383
S + DEDD E+ +E D+ G Q + A +E S+ES S
Sbjct: 915 STPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSS 974
Query: 384 EADRA-QKMDGESEEEQESVDTGEEE-EGGDESDLSSESSIK-KKFLKRKGKTDSPWIKP 440
E D + D E E+ +E+VDT ++E E D D S+SS K + G+ DS
Sbjct: 975 EKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSE 1034
Query: 441 ARKRRRRSRKKPSGALGSESYKSSAGSAE 469
+ S S + S S SS S+E
Sbjct: 1035 SSSSSSSSSSSSSSSSSSSSSSSSESSSE 1063
Score = 35.4 bits (80), Expect = 0.21
Identities = 27/99 (27%), Positives = 40/99 (40%), Gaps = 3/99 (3%)
Query: 326 SKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESM--- 382
S+GE+ SS + E E D +++D EE + E + E +SK S+
Sbjct: 963 SEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYAD 1022
Query: 383 SEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESS 421
S+ + D ES S + S SSESS
Sbjct: 1023 SDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESS 1061
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 44.7 bits (104), Expect = 4e-04
Identities = 32/133 (24%), Positives = 58/133 (43%), Gaps = 9/133 (6%)
Query: 322 STVGSKGEKDLGASSLHVNGESLEMDSDEDDSEEL--EEDDGHGAEQAAAFPTEDSRTSK 379
S S E + G+ S E DS+ED SE+ E+D G E E+ RT+K
Sbjct: 686 SDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESG----LENKRTAK 741
Query: 380 ESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIK 439
+ ++ DGE E E+ +E D SS+S + + + +++S +
Sbjct: 742 RNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESES---EPESESESRRVT 798
Query: 440 PARKRRRRSRKKP 452
++++ + + P
Sbjct: 799 KEKEKKTKQDRTP 811
Score = 37.4 bits (85), Expect = 0.056
Identities = 28/126 (22%), Positives = 54/126 (42%)
Query: 326 SKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEA 385
S+ E++ +S + ES + E EE D + + +DS + +ES E
Sbjct: 677 SESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESGLEN 736
Query: 386 DRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPARKRR 445
R K + +++ + +S D +E E SD S++ S + +++S + RR
Sbjct: 737 KRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESESRR 796
Query: 446 RRSRKK 451
K+
Sbjct: 797 VTKEKE 802
Score = 35.8 bits (81), Expect = 0.16
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 26/135 (19%)
Query: 365 EQAAAFPTEDSRTSKESMSEADRAQ-KMDGESEEEQES-VDTGEEEEGGDESDLSSESS- 421
E A + ++K+ SE++ + D S+ E ES ++GE+ E G+E D + +SS
Sbjct: 659 EWTPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSE 718
Query: 422 --------------------IKKKFLKRKGKTDSPWIKPARKRRRRSRKKPSGALGSESY 461
K+ K KGK+DS + K +S+ S S S
Sbjct: 719 DSSSEQDSESGRESGLENKRTAKRNSKAKGKSDS---EDGEKENEKSKTSDSSNDESSSI 775
Query: 462 KSSAGSAEQTAPGDS 476
+ S+ +E + +S
Sbjct: 776 EDSSSDSESESEPES 790
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 44.7 bits (104), Expect = 4e-04
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 4/133 (3%)
Query: 325 GSKGEKDLGASSLHVN-GESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMS 383
G + +KD SSL G+ + D D ++ E++ G +A E+ K++
Sbjct: 96 GHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEE 155
Query: 384 EADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKF--LKRKGKTDSPWIKPA 441
EA+ K ++E E E++ ++E + L E +K+F L RK + P +
Sbjct: 156 EAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRK-MLEDPQERER 214
Query: 442 RKRRRRSRKKPSG 454
R+RR R ++ +G
Sbjct: 215 RERRERMERETNG 227
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 44.3 bits (103), Expect = 5e-04
Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Query: 367 AAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKF 426
+ A P +++S ES SE + + SEEE+E + EEEE + SD E + +
Sbjct: 466 STAMPPGLAKSSSESSSEESSS---ESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAE 522
Query: 427 LKRK---------GKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAE 469
L+ + + P KP RKR ++ +KK A E ++ AG+ E
Sbjct: 523 LQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKA---EKHRGRAGADE 571
Score = 33.1 bits (74), Expect = 1.1
Identities = 46/163 (28%), Positives = 66/163 (40%), Gaps = 38/163 (23%)
Query: 343 SLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESV 402
S E S E SEE EE+D E+ S+ S SE +RA ++ E +E+ +V
Sbjct: 481 SSEESSSESSSEEEEEEDEED---------EEEEESESSDSEEERAHRL-AELQEQLRAV 530
Query: 403 DTGEEEEGGDESDLS--------SESSIKKKFLKRKGKT----DSPWIKPARKRRRRSRK 450
E+ + +S E K+K K +G+ D + R + + K
Sbjct: 531 H--EQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSK 588
Query: 451 KPSG------ALGSESYKSSAGS-------AEQTA-PGDSTGY 479
K SG ALG + S GS A +TA P TGY
Sbjct: 589 KASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGY 631
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 44.3 bits (103), Expect = 5e-04
Identities = 33/112 (29%), Positives = 53/112 (47%), Gaps = 15/112 (13%)
Query: 367 AAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKF 426
+ A P +++S ES SE + + SEEE+E + EEEE + SD E + +
Sbjct: 466 STAMPPGLAKSSSESSSEESSS---ESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAE 522
Query: 427 LKRK---------GKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAE 469
L+ + + P KP RKR ++ +KK A E ++ AG+ E
Sbjct: 523 LQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKA---EKHRGRAGADE 571
Score = 33.1 bits (74), Expect = 1.1
Identities = 46/163 (28%), Positives = 66/163 (40%), Gaps = 38/163 (23%)
Query: 343 SLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESV 402
S E S E SEE EE+D E+ S+ S SE +RA ++ E +E+ +V
Sbjct: 481 SSEESSSESSSEEEEEEDEED---------EEEEESESSDSEEERAHRL-AELQEQLRAV 530
Query: 403 DTGEEEEGGDESDLS--------SESSIKKKFLKRKGKT----DSPWIKPARKRRRRSRK 450
E+ + +S E K+K K +G+ D + R + + K
Sbjct: 531 H--EQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSK 588
Query: 451 KPSG------ALGSESYKSSAGS-------AEQTA-PGDSTGY 479
K SG ALG + S GS A +TA P TGY
Sbjct: 589 KASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGY 631
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 44.3 bits (103), Expect = 5e-04
Identities = 63/277 (22%), Positives = 108/277 (38%), Gaps = 36/277 (12%)
Query: 208 PKSVVGLHAASKDPREVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSLPQNQCYM 267
P + G+ A +E R K +E SD RQ+ LP S + + Y
Sbjct: 114 PPAKNGVAAEVSPAKEENPRRASKAVEES-----SDEERQRDLPAQRGEESSEEEEKGYK 168
Query: 268 ATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSK 327
T+ + P V KK+ G S V +K+ + + + E + G+K
Sbjct: 169 GKTRKK----PVV--------KKQAPGKAS-VSRKQAREESEESEAEPVQRTAKKVEGNK 215
Query: 328 GEKDLGASSLHVNGESL----EMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKE--S 381
G K L S E L E +E + EE EED+ G + ++++E S
Sbjct: 216 GTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERS 275
Query: 382 MSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKFLKRKGKTDSPWIKPA 441
+ +A+++ G+S+ E+E E GD+S E +++K D +K
Sbjct: 276 CKQKSQAKRLLGDSDSEEEQ---KEAASSGDDSGRDREPPVQRK------SEDRTQLKGG 326
Query: 442 RKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTG 478
++ S + G + K GS + G ++G
Sbjct: 327 KRLSGSSEDEEDSGKGEPTAK---GSRKMARLGSTSG 360
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 44.3 bits (103), Expect = 5e-04
Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 32/155 (20%)
Query: 342 ESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSK--------ESMSEADRAQKMDG 393
E EM ++ +++EE EE+D +E AA P + S + + E E R +
Sbjct: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
Query: 394 ESEEEQESVDTGEEEE---------------GGDESDLSSESSIKKKFLKRKGKTD---S 435
+SEEEQ+ ++ E EE DE D ES+ KK+ ++ + D
Sbjct: 1285 QSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEE 1344
Query: 436 PWIKPA------RKRRRRSRKKPSGALGSESYKSS 464
P ++ + +K R + + K L SE + S
Sbjct: 1345 PGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379
Score = 40.8 bits (94), Expect = 0.005
Identities = 63/265 (23%), Positives = 103/265 (38%), Gaps = 42/265 (15%)
Query: 211 VVGLHAASKDPREVREARDHKEPKEE-------INKNISDFGRQQLLPPFPSLHQSLPQN 263
+V S++ E E +++EP+ + + K++S ++Q + + P+
Sbjct: 780 IVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQ--DSYSVESEKKPEV 837
Query: 264 QCYMATTKSQTACLPFVLAAAVSRKKKR-RMGTYSLVPKKKTKVLKQRTVIEMFKSITHS 322
+++T+ LP A S+ +R R G + +++ + ++E S
Sbjct: 838 MAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQE 897
Query: 323 TVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD-----GHGAE----QAAAFP-- 371
G GEK + E + S+E S++ + D G E Q P
Sbjct: 898 QYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEA 957
Query: 372 -----TEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKF 426
TE S SE DRA + G SE + EEEE + SS + K
Sbjct: 958 LKCRLTEGSERLPRRYSEGDRAV-LRGFSE-------SSEEEEEPESPRSSSPPILTKPT 1009
Query: 427 LKRKGKTDSPWIKPARKRRRRSRKK 451
LKRK KP RRRR RK+
Sbjct: 1010 LKRK--------KPFLHRRRRVRKR 1026
Score = 32.0 bits (71), Expect = 2.4
Identities = 47/266 (17%), Positives = 96/266 (36%), Gaps = 39/266 (14%)
Query: 194 PGADVKVHRARKTMPKS--------VVGLHAASKDPREVREARDHKEPKEEINKNISDFG 245
PG +R+ MP S +V + A + P+ ++E+ + EPKE++
Sbjct: 1167 PGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPK-IQESEETVEPKEDM-------- 1217
Query: 246 RQQLLPPFPSLHQSLPQNQCYM--ATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKK 303
P P + + Q A + + AA T + P+ +
Sbjct: 1218 ------PLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVE 1271
Query: 304 TKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHG 363
+ K R E +S + E + + ++ + D+D++D LE
Sbjct: 1272 EEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKE 1331
Query: 364 AEQAA-------------AFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEG 410
E+ +F + + S+E + + + + +D E E+ E+
Sbjct: 1332 LEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETE-LDSEEEQPSHDTSVVSEQMA 1390
Query: 411 GDESDLSSESSIKKKFLKRKGKTDSP 436
G E D +S K++ ++ K + + P
Sbjct: 1391 GSEDDHEEDSHTKEELIELKEEEEIP 1416
Score = 30.4 bits (67), Expect = 6.9
Identities = 32/147 (21%), Positives = 56/147 (38%), Gaps = 12/147 (8%)
Query: 378 SKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSE--------SSIKKKFLKR 429
S+E++ + + EEE+ + E EEG +E SSE SS + +
Sbjct: 1207 SEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETK 1266
Query: 430 KGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYMEVSLDSLDL 489
+ + + KP +R ++ L + +A +TA D + D D
Sbjct: 1267 EPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD----HDADDEDDG 1322
Query: 490 RVKGILSSQAEGLANGPDVLETDGLQE 516
++ + E DV E G+QE
Sbjct: 1323 HLESTKKKELEEQPTREDVKEEPGVQE 1349
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 44.3 bits (103), Expect = 5e-04
Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 32/155 (20%)
Query: 342 ESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSK--------ESMSEADRAQKMDG 393
E EM ++ +++EE EE+D +E AA P + S + + E E R +
Sbjct: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
Query: 394 ESEEEQESVDTGEEEE---------------GGDESDLSSESSIKKKFLKRKGKTD---S 435
+SEEEQ+ ++ E EE DE D ES+ KK+ ++ + D
Sbjct: 1285 QSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEE 1344
Query: 436 PWIKPA------RKRRRRSRKKPSGALGSESYKSS 464
P ++ + +K R + + K L SE + S
Sbjct: 1345 PGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379
Score = 40.8 bits (94), Expect = 0.005
Identities = 63/265 (23%), Positives = 103/265 (38%), Gaps = 42/265 (15%)
Query: 211 VVGLHAASKDPREVREARDHKEPKEE-------INKNISDFGRQQLLPPFPSLHQSLPQN 263
+V S++ E E +++EP+ + + K++S ++Q + + P+
Sbjct: 780 IVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQ--DSYSVESEKKPEV 837
Query: 264 QCYMATTKSQTACLPFVLAAAVSRKKKR-RMGTYSLVPKKKTKVLKQRTVIEMFKSITHS 322
+++T+ LP A S+ +R R G + +++ + ++E S
Sbjct: 838 MAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQE 897
Query: 323 TVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD-----GHGAE----QAAAFP-- 371
G GEK + E + S+E S++ + D G E Q P
Sbjct: 898 QYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEA 957
Query: 372 -----TEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKF 426
TE S SE DRA + G SE + EEEE + SS + K
Sbjct: 958 LKCRLTEGSERLPRRYSEGDRAV-LRGFSE-------SSEEEEEPESPRSSSPPILTKPT 1009
Query: 427 LKRKGKTDSPWIKPARKRRRRSRKK 451
LKRK KP RRRR RK+
Sbjct: 1010 LKRK--------KPFLHRRRRVRKR 1026
Score = 32.0 bits (71), Expect = 2.4
Identities = 47/266 (17%), Positives = 96/266 (36%), Gaps = 39/266 (14%)
Query: 194 PGADVKVHRARKTMPKS--------VVGLHAASKDPREVREARDHKEPKEEINKNISDFG 245
PG +R+ MP S +V + A + P+ ++E+ + EPKE++
Sbjct: 1167 PGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPK-IQESEETVEPKEDM-------- 1217
Query: 246 RQQLLPPFPSLHQSLPQNQCYM--ATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKK 303
P P + + Q A + + AA T + P+ +
Sbjct: 1218 ------PLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVE 1271
Query: 304 TKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHG 363
+ K R E +S + E + + ++ + D+D++D LE
Sbjct: 1272 EEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKE 1331
Query: 364 AEQAA-------------AFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEG 410
E+ +F + + S+E + + + + +D E E+ E+
Sbjct: 1332 LEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETE-LDSEEEQPSHDTSVVSEQMA 1390
Query: 411 GDESDLSSESSIKKKFLKRKGKTDSP 436
G E D +S K++ ++ K + + P
Sbjct: 1391 GSEDDHEEDSHTKEELIELKEEEEIP 1416
Score = 30.4 bits (67), Expect = 6.9
Identities = 32/147 (21%), Positives = 56/147 (38%), Gaps = 12/147 (8%)
Query: 378 SKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSE--------SSIKKKFLKR 429
S+E++ + + EEE+ + E EEG +E SSE SS + +
Sbjct: 1207 SEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETK 1266
Query: 430 KGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYMEVSLDSLDL 489
+ + + KP +R ++ L + +A +TA D + D D
Sbjct: 1267 EPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD----HDADDEDDG 1322
Query: 490 RVKGILSSQAEGLANGPDVLETDGLQE 516
++ + E DV E G+QE
Sbjct: 1323 HLESTKKKELEEQPTREDVKEEPGVQE 1349
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 44.3 bits (103), Expect = 5e-04
Identities = 40/155 (25%), Positives = 67/155 (43%), Gaps = 32/155 (20%)
Query: 342 ESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSK--------ESMSEADRAQKMDG 393
E EM ++ +++EE EE+D +E AA P + S + + E E R +
Sbjct: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
Query: 394 ESEEEQESVDTGEEEE---------------GGDESDLSSESSIKKKFLKRKGKTD---S 435
+SEEEQ+ ++ E EE DE D ES+ KK+ ++ + D
Sbjct: 1285 QSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEE 1344
Query: 436 PWIKPA------RKRRRRSRKKPSGALGSESYKSS 464
P ++ + +K R + + K L SE + S
Sbjct: 1345 PGVQESFLDANMQKSREKIKDKEETELDSEEEQPS 1379
Score = 40.8 bits (94), Expect = 0.005
Identities = 63/265 (23%), Positives = 103/265 (38%), Gaps = 42/265 (15%)
Query: 211 VVGLHAASKDPREVREARDHKEPKEE-------INKNISDFGRQQLLPPFPSLHQSLPQN 263
+V S++ E E +++EP+ + + K++S ++Q + + P+
Sbjct: 780 IVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQ--DSYSVESEKKPEV 837
Query: 264 QCYMATTKSQTACLPFVLAAAVSRKKKR-RMGTYSLVPKKKTKVLKQRTVIEMFKSITHS 322
+++T+ LP A S+ +R R G + +++ + ++E S
Sbjct: 838 MAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDSKLLLEETSSAPQE 897
Query: 323 TVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD-----GHGAE----QAAAFP-- 371
G GEK + E + S+E S++ + D G E Q P
Sbjct: 898 QYGECGEKSEATQEQYTESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEA 957
Query: 372 -----TEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSESSIKKKF 426
TE S SE DRA + G SE + EEEE + SS + K
Sbjct: 958 LKCRLTEGSERLPRRYSEGDRAV-LRGFSE-------SSEEEEEPESPRSSSPPILTKPT 1009
Query: 427 LKRKGKTDSPWIKPARKRRRRSRKK 451
LKRK KP RRRR RK+
Sbjct: 1010 LKRK--------KPFLHRRRRVRKR 1026
Score = 32.0 bits (71), Expect = 2.4
Identities = 47/266 (17%), Positives = 96/266 (36%), Gaps = 39/266 (14%)
Query: 194 PGADVKVHRARKTMPKS--------VVGLHAASKDPREVREARDHKEPKEEINKNISDFG 245
PG +R+ MP S +V + A + P+ ++E+ + EPKE++
Sbjct: 1167 PGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPK-IQESEETVEPKEDM-------- 1217
Query: 246 RQQLLPPFPSLHQSLPQNQCYM--ATTKSQTACLPFVLAAAVSRKKKRRMGTYSLVPKKK 303
P P + + Q A + + AA T + P+ +
Sbjct: 1218 ------PLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVE 1271
Query: 304 TKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHG 363
+ K R E +S + E + + ++ + D+D++D LE
Sbjct: 1272 EEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKE 1331
Query: 364 AEQAA-------------AFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEG 410
E+ +F + + S+E + + + + +D E E+ E+
Sbjct: 1332 LEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETE-LDSEEEQPSHDTSVVSEQMA 1390
Query: 411 GDESDLSSESSIKKKFLKRKGKTDSP 436
G E D +S K++ ++ K + + P
Sbjct: 1391 GSEDDHEEDSHTKEELIELKEEEEIP 1416
Score = 30.4 bits (67), Expect = 6.9
Identities = 32/147 (21%), Positives = 56/147 (38%), Gaps = 12/147 (8%)
Query: 378 SKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESDLSSE--------SSIKKKFLKR 429
S+E++ + + EEE+ + E EEG +E SSE SS + +
Sbjct: 1207 SEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETK 1266
Query: 430 KGKTDSPWIKPARKRRRRSRKKPSGALGSESYKSSAGSAEQTAPGDSTGYMEVSLDSLDL 489
+ + + KP +R ++ L + +A +TA D + D D
Sbjct: 1267 EPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDD----HDADDEDDG 1322
Query: 490 RVKGILSSQAEGLANGPDVLETDGLQE 516
++ + E DV E G+QE
Sbjct: 1323 HLESTKKKELEEQPTREDVKEEPGVQE 1349
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 44.3 bits (103), Expect = 5e-04
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 28/155 (18%)
Query: 321 HSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKE 380
H T GS G D ++ E +E D +ED EE+EED ED ++
Sbjct: 183 HET-GSSGSSDEQGNNTENEEEGVEEDVEED--EEVEED-----------AEEDEEVDED 228
Query: 381 SMSEADRAQKMDGESEEEQESVDTGE---EEEGGD---ESDLSSESSIKKKFLKRKGKTD 434
E + ++ + E EEE+E + E +EEG D S+ S S F ++
Sbjct: 229 GEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSG 288
Query: 435 SPWIKPARKRRRRSRKK--------PSGALGSESY 461
S K++ R R + SG+ SESY
Sbjct: 289 SGTDGSDEKKKERKRARGISPIVFDRSGSSASESY 323
Score = 35.0 bits (79), Expect = 0.28
Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 11/115 (9%)
Query: 301 KKKTKVLKQRTVIEMFKSITHSTVGSKGEKDLGASSLHVNGESLEMDSDEDDSEELEEDD 360
K T +R +E+ + + S+ SK E VN E D + S +E
Sbjct: 145 KSPTPDGSERIGLEVDRRASRSSQSSKEE---------VNSEEYGSDHETGSSGSSDEQ- 194
Query: 361 GHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDTGEEEEGGDESD 415
G+ E ED +E +A+ +++D + EEE+E + EEEE +E +
Sbjct: 195 GNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEE-EEEEEEEEEEEEE 248
Score = 30.4 bits (67), Expect = 6.9
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 2/75 (2%)
Query: 345 EMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKMDGESEEEQESVDT 404
E++S+E S+ G EQ TE+ E E D + D E +EE +
Sbjct: 173 EVNSEEYGSDHETGSSGSSDEQGNN--TENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230
Query: 405 GEEEEGGDESDLSSE 419
EEEE +E + E
Sbjct: 231 EEEEEEEEEEEEEEE 245
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 43.9 bits (102), Expect = 6e-04
Identities = 47/213 (22%), Positives = 88/213 (41%), Gaps = 22/213 (10%)
Query: 221 PREVREARDHKEPKEEINKNISDFGRQQLLPPFPSLHQSL---------PQNQCYMATTK 271
P+EV E + +E E+ + S G + ++P + P + +AT
Sbjct: 21 PKEVEEDSEDEEMSEDEEDDSS--GEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPA 78
Query: 272 SQTACLPFVLAAAVSRKKKRRMGTYSLVPKKKTKVLKQRTVIEMFKSITHSTVGSKGEKD 331
+ A P AAA KK P KK + V K + + +KG K+
Sbjct: 79 KKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKK--GAAIPAKGAKN 136
Query: 332 LGASSLHVNGESLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKESMSEADRAQKM 391
+ + E + DS+ED+ ++ +ED+ + AA ++ + A ++
Sbjct: 137 GKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAM---------KAAAAAPASEDE 187
Query: 392 DGESEEEQESVDTGEEEEGGDESDLSSESSIKK 424
D E +E+ E D EE++ +E+ ++ + KK
Sbjct: 188 DDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKK 220
Score = 40.8 bits (94), Expect = 0.005
Identities = 36/163 (22%), Positives = 73/163 (44%), Gaps = 17/163 (10%)
Query: 343 SLEMDSDEDDSEELEEDDGHGAEQAAAFPTEDSRTSKES----MSEADRAQKMDGESEEE 398
S + D ++D+ +E ++DD + A T ++ K + + + A+ D E ++E
Sbjct: 184 SEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDE 243
Query: 399 QESVDTGEEEEGGDESD------LSSESSIKKKFLKRKGKTDSPWIKPARKRRRRSRKKP 452
E D E++E D+ D E +K+ KRK + P K+++ +P
Sbjct: 244 DEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEP 303
Query: 453 SGA----LGSESYKSSAGSAEQTAPGDSTGYMEVSLDSLDLRV 491
+ A +G+ ++ SA + G S + + L +D+R+
Sbjct: 304 TTAFNLFVGNLNFNK---SAPELKTGISDVFAKNDLAVVDVRI 343
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,362,695
Number of Sequences: 37866
Number of extensions: 1817359
Number of successful extensions: 16256
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 210
Number of HSP's successfully gapped in prelim test: 588
Number of HSP's that attempted gapping in prelim test: 10712
Number of HSP's gapped (non-prelim): 3704
length of query: 808
length of database: 18,247,518
effective HSP length: 110
effective length of query: 698
effective length of database: 14,082,258
effective search space: 9829416084
effective search space used: 9829416084
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.