Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 224451080
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224451080 cytospin A [Homo sapiens]
(1117 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224451082 cytospin A [Homo sapiens] 2151 0.0
gi|224451080 cytospin A [Homo sapiens] 2151 0.0
gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo sa... 688 0.0
gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo sa... 676 0.0
gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo sa... 434 e-121
gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo sa... 421 e-117
gi|19913396 smoothelin isoform b [Homo sapiens] 110 7e-24
gi|157738619 smoothelin-like 1 [Homo sapiens] 107 8e-23
gi|19913398 smoothelin isoform a [Homo sapiens] 104 5e-22
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 102 3e-21
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 102 3e-21
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 102 3e-21
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 102 3e-21
gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens] 100 1e-20
gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens] 100 1e-20
gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens] 100 1e-20
gi|19913394 smoothelin isoform c [Homo sapiens] 100 1e-20
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens] 99 2e-20
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 97 1e-19
gi|169234649 smoothelin-like 2 isoform 2 [Homo sapiens] 97 1e-19
gi|169234647 smoothelin-like 2 isoform 1 [Homo sapiens] 97 1e-19
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 96 2e-19
gi|67782321 spectrin beta isoform a [Homo sapiens] 96 2e-19
gi|67782319 spectrin beta isoform b [Homo sapiens] 96 2e-19
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 94 9e-19
gi|156104908 myosin heavy chain 6 [Homo sapiens] 94 9e-19
gi|31982906 cingulin-like 1 [Homo sapiens] 94 9e-19
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 94 9e-19
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 94 9e-19
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 93 1e-18
>gi|224451082 cytospin A [Homo sapiens]
Length = 1117
Score = 2151 bits (5573), Expect = 0.0
Identities = 1117/1117 (100%), Positives = 1117/1117 (100%)
Query: 1 MKKASRSVGSVPKVSAISKTQTAEKIKPENSSSASTGGKLVKPGTAASLSKTKSSDDLLA 60
MKKASRSVGSVPKVSAISKTQTAEKIKPENSSSASTGGKLVKPGTAASLSKTKSSDDLLA
Sbjct: 1 MKKASRSVGSVPKVSAISKTQTAEKIKPENSSSASTGGKLVKPGTAASLSKTKSSDDLLA 60
Query: 61 GMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGNKESS 120
GMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGNKESS
Sbjct: 61 GMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGNKESS 120
Query: 121 STRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAA 180
STRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAA
Sbjct: 121 STRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAA 180
Query: 181 LEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVE 240
LEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVE
Sbjct: 181 LEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVE 240
Query: 241 STLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITP 300
STLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITP
Sbjct: 241 STLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITP 300
Query: 301 DNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSD 360
DNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSD
Sbjct: 301 DNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSD 360
Query: 361 DALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQE 420
DALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQE
Sbjct: 361 DALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQE 420
Query: 421 LADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVID 480
LADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVID
Sbjct: 421 LADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVID 480
Query: 481 EDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKER 540
EDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKER
Sbjct: 481 EDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKER 540
Query: 541 SHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSG 600
SHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSG
Sbjct: 541 SHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSG 600
Query: 601 DKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKK 660
DKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKK
Sbjct: 601 DKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKK 660
Query: 661 QIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKK 720
QIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKK
Sbjct: 661 QIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKK 720
Query: 721 LQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHE 780
LQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHE
Sbjct: 721 LQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHE 780
Query: 781 AQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPT 840
AQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPT
Sbjct: 781 AQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPT 840
Query: 841 VKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTA 900
VKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTA
Sbjct: 841 VKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTA 900
Query: 901 LSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEG 960
LSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEG
Sbjct: 901 LSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEG 960
Query: 961 ASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKW 1020
ASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKW
Sbjct: 961 ASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKW 1020
Query: 1021 CQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAE 1080
CQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAE
Sbjct: 1021 CQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAE 1080
Query: 1081 SVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET 1117
SVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET
Sbjct: 1081 SVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET 1117
>gi|224451080 cytospin A [Homo sapiens]
Length = 1117
Score = 2151 bits (5573), Expect = 0.0
Identities = 1117/1117 (100%), Positives = 1117/1117 (100%)
Query: 1 MKKASRSVGSVPKVSAISKTQTAEKIKPENSSSASTGGKLVKPGTAASLSKTKSSDDLLA 60
MKKASRSVGSVPKVSAISKTQTAEKIKPENSSSASTGGKLVKPGTAASLSKTKSSDDLLA
Sbjct: 1 MKKASRSVGSVPKVSAISKTQTAEKIKPENSSSASTGGKLVKPGTAASLSKTKSSDDLLA 60
Query: 61 GMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGNKESS 120
GMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGNKESS
Sbjct: 61 GMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGNKESS 120
Query: 121 STRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAA 180
STRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAA
Sbjct: 121 STRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAA 180
Query: 181 LEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVE 240
LEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVE
Sbjct: 181 LEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVE 240
Query: 241 STLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITP 300
STLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITP
Sbjct: 241 STLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITP 300
Query: 301 DNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSD 360
DNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSD
Sbjct: 301 DNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSD 360
Query: 361 DALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQE 420
DALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQE
Sbjct: 361 DALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQE 420
Query: 421 LADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVID 480
LADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVID
Sbjct: 421 LADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVID 480
Query: 481 EDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKER 540
EDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKER
Sbjct: 481 EDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKER 540
Query: 541 SHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSG 600
SHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSG
Sbjct: 541 SHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSG 600
Query: 601 DKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKK 660
DKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKK
Sbjct: 601 DKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKK 660
Query: 661 QIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKK 720
QIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKK
Sbjct: 661 QIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKK 720
Query: 721 LQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHE 780
LQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHE
Sbjct: 721 LQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHE 780
Query: 781 AQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPT 840
AQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPT
Sbjct: 781 AQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPT 840
Query: 841 VKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTA 900
VKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTA
Sbjct: 841 VKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTA 900
Query: 901 LSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEG 960
LSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEG
Sbjct: 901 LSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEG 960
Query: 961 ASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKW 1020
ASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKW
Sbjct: 961 ASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKW 1020
Query: 1021 CQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAE 1080
CQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAE
Sbjct: 1021 CQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAE 1080
Query: 1081 SVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET 1117
SVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET
Sbjct: 1081 SVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET 1117
>gi|75750472 spectrin domain with coiled-coils 1 NSP5b3b [Homo
sapiens]
Length = 1068
Score = 688 bits (1776), Expect = 0.0
Identities = 450/1118 (40%), Positives = 645/1118 (57%), Gaps = 109/1118 (9%)
Query: 33 SASTGGKLVKPGTAASLS------KTKSSDDLLAGMAGGVTVTNGVKGKKSTCPSAAPSA 86
+AS+G K K T+ + K SS+D L G T +GV K T + A S
Sbjct: 27 AASSGMKSSKSSTSLAFESRLSRLKRASSEDTLN--KPGSTAASGVVRLKKTATAGAISE 84
Query: 87 SAPAMTTVENKSKISTGTASSTKRSTSTGNKESSSTRERLRERTR-LNQSKKLPSAGQGA 145
E++ + TG ++TKR+ +E S T R R R + +K S+ +
Sbjct: 85 ------LTESRLRSGTGAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSS 138
Query: 146 NDMALAKRSRSRTATECDVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNE 205
N K R+ + +K K +N+ ++AALE++V++LL AK KD EI LR+E
Sbjct: 139 NTPTPTKHLRTPS--------TKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSE 190
Query: 206 LRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENR 265
L+ + + +N + ++ + T ++ P D E + L+E+N ++EL+ L+ ENR
Sbjct: 191 LKKYKEKRTLNAEGTDALGPNVDGTSVS--PGDTEPMIRALEEKNKNFQKELSDLEEENR 248
Query: 266 MLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDL 325
+LK++L L S NSE + S T Q G+ T +
Sbjct: 249 VLKEKLIYLEHS-----PNSEGAASHTGDSSCPTSITQESSFGSPTGNQ----------- 292
Query: 326 LSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSD---------DALDAPSSSESEGIPS 376
+S D + + H N++ S S+V + S D + P SS S S
Sbjct: 293 MSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPFKS 352
Query: 377 IERSRKGSSGNA-SEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSEN 435
+ S GSS N+ SE+S+A LTE+I +MEEN HST+EELQATLQEL+D QQ+ QEL +EN
Sbjct: 353 SKCSTAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAEN 412
Query: 436 ERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDED--VKSGRYMELEQ 493
E+L +EK IL S Q ++ E S++ E +LL E V +E+ + G+ +ELEQ
Sbjct: 413 EKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQER----VKNEEPTTQEGKIIELEQ 468
Query: 494 RYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQK 553
+ + E RFERE+LL +QQ L+ +L+ E++N+ A EMI LKE + + +E E+
Sbjct: 469 KCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERH 528
Query: 554 GKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVR 613
+A TLEE + T+ ++E LK+ L+ EKQK E ++ + + ++Q++L+ R
Sbjct: 529 NNNMMAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVAR 588
Query: 614 LDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLR 673
+K+ E + L+++L + + +AKVE +Y +E Q E L+ T KL+
Sbjct: 589 AEKDLLELSCNELRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQ 648
Query: 674 SDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIK 733
E + E DMKETIFELED+VEQHRAVKLH+N +IS+LE++V KL++QK D+ER++K
Sbjct: 649 EKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQKSDLERQLK 708
Query: 734 TLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELE 793
TL ++++EE+ EWR+FQADLQTAVV+ANDIK EAQ+E+ +KR+L E +EKN +L KEL
Sbjct: 709 TLTKQMKEETEEWRRFQADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKNARLQKELG 768
Query: 794 EIKSRKQEEERGRVYNYMNA----------VERDLAALRQGMGLSRRSSTSSEPTPTVKT 843
+++ GRV A E D A G+ +SR S T E TVK+
Sbjct: 769 DVQG------HGRVVTSRAAPPPVDEEPESSEVDAAGRWPGVCVSRTSPTPPESATTVKS 822
Query: 844 LIKSFD---SASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTA 900
LIKSFD N + PR+PLS P++T PAAAVSPMQRHS S+ +P +
Sbjct: 823 LIKSFDLGRPGGAGQNISVHKTPRSPLSGIPVRTAPAAAVSPMQRHS---TYSSVRPASR 879
Query: 901 LSDKRPNYGEIPVQEHLL-RTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQE 959
+R + ++P+ + L RT + L + P++E S+SR S
Sbjct: 880 GVTQRLDLPDLPLSDILKGRTETLKPDPHLRKSPSLE-----SLSRPPS----------- 923
Query: 960 GASPASLMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLK 1019
+ G T L S+ T + P +S++ ERKDPL+ALAREYGGSKRNALLK
Sbjct: 924 -------LGFGDT----RLLSASTRAWKP--QSKLSVERKDPLAALAREYGGSKRNALLK 970
Query: 1020 WCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAA 1079
WCQKKT+GY NIDITNFSSSW+DGLAFCALLHTYLPAHIPYQELNSQ+K+RN +LAF+AA
Sbjct: 971 WCQKKTQGYANIDITNFSSSWSDGLAFCALLHTYLPAHIPYQELNSQEKKRNLLLAFEAA 1030
Query: 1080 ESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET 1117
ESVGIK +L+++EM+ T+RPDWQ+VM YV IYKYFET
Sbjct: 1031 ESVGIKPSLELSEMLYTDRPDWQSVMQYVAQIYKYFET 1068
>gi|75750474 spectrin domain with coiled-coils 1 NSP5a3b [Homo
sapiens]
Length = 987
Score = 676 bits (1744), Expect = 0.0
Identities = 429/1042 (41%), Positives = 614/1042 (58%), Gaps = 95/1042 (9%)
Query: 103 GTASSTKRSTSTGNKESSSTRERLRERTR-LNQSKKLPSAGQGANDMALAKRSRSRTATE 161
G ++TKR+ +E S T R R R + +K S+ +N K R+ +
Sbjct: 14 GAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTPTPTKHLRTPS--- 70
Query: 162 CDVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSE 221
+K K +N+ ++AALE++V++LL AK KD EI LR+EL+ + + +N + ++
Sbjct: 71 -----TKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTLNAEGTD 125
Query: 222 GDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQR 281
+ T ++ P D E + L+E+N ++EL+ L+ ENR+LK++L L S
Sbjct: 126 ALGPNVDGTSVS--PGDTEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIYLEHS---- 179
Query: 282 LDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNS 341
NSE + S T Q G+ T + +S D + + H N+
Sbjct: 180 -PNSEGAASHTGDSSCPTSITQESSFGSPTGNQ-----------MSSDIDEYKKNIHGNA 227
Query: 342 MDNLDSECSEVYQPLTSSD---------DALDAPSSSESEGIPSIERSRKGSSGNA-SEV 391
+ S S+V + S D + P SS S S + S GSS N+ SE+
Sbjct: 228 LRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPFKSSKCSTAGSSPNSVSEL 287
Query: 392 SVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQ 451
S+A LTE+I +MEEN HST+EELQATLQEL+D QQ+ QEL +ENE+L +EK IL S Q
Sbjct: 288 SLASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVDEKTILETSFHQ 347
Query: 452 QSDKLEHFSRQIEYFRSLLDEHHISYVIDED--VKSGRYMELEQRYMDLAENARFEREQL 509
++ E S++ E +LL E V +E+ + G+ +ELEQ+ + E RFERE+L
Sbjct: 348 HRERAEQLSQENEKLMNLLQER----VKNEEPTTQEGKIIELEQKCTGILEQGRFEREKL 403
Query: 510 LGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATV 569
L +QQ L+ +L+ E++N+ A EMI LKE + + +E E+ +A TLEE + T+
Sbjct: 404 LNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTL 463
Query: 570 ASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQED 629
++E LK+ L+ EKQK E ++ + + ++Q++L+ R +K+ E + L+++
Sbjct: 464 EGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNELRQE 523
Query: 630 LAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKET 689
L + + +AKVE +Y +E Q E L+ T KL+ E + E DMKET
Sbjct: 524 LLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEKASESDAEIKDMKET 583
Query: 690 IFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQF 749
IFELED+VEQHRAVKLH+N +IS+LE++V KL++QK D+ER++KTL ++++EE+ EWR+F
Sbjct: 584 IFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEETEEWRRF 643
Query: 750 QADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYN 809
QADLQTAVV+ANDIK EAQ+E+ +KR+L E +EKN +L KEL +++ GRV
Sbjct: 644 QADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKNARLQKELGDVQG------HGRVVT 697
Query: 810 YMNA----------VERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFD---SASQVPN 856
A E D A G+ +SR S T E TVK+LIKSFD N
Sbjct: 698 SRAAPPPVDEEPESSEVDAAGRWPGVCVSRTSPTPPESATTVKSLIKSFDLGRPGGAGQN 757
Query: 857 PAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEH 916
+ PR+PLS P++T PAAAVSPMQRHS S+ +P + +R + ++P+ +
Sbjct: 758 ISVHKTPRSPLSGIPVRTAPAAAVSPMQRHS---TYSSVRPASRGVTQRLDLPDLPLSDI 814
Query: 917 LL-RTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEGASPASLMAMGTTSPQ 975
L RT + L + P++E S+SR S + G T
Sbjct: 815 LKGRTETLKPDPHLRKSPSLE-----SLSRPPS------------------LGFGDT--- 848
Query: 976 LSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITN 1035
L S+ T + P +S++ ERKDPL+ALAREYGGSKRNALLKWCQKKT+GY NIDITN
Sbjct: 849 -RLLSASTRAWKP--QSKLSVERKDPLAALAREYGGSKRNALLKWCQKKTQGYANIDITN 905
Query: 1036 FSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAESVGIKSTLDINEMVR 1095
FSSSW+DGLAFCALLHTYLPAHIPYQELNSQ+K+RN +LAF+AAESVGIK +L+++EM+
Sbjct: 906 FSSSWSDGLAFCALLHTYLPAHIPYQELNSQEKKRNLLLAFEAAESVGIKPSLELSEMLY 965
Query: 1096 TERPDWQNVMLYVTAIYKYFET 1117
T+RPDWQ+VM YV IYKYFET
Sbjct: 966 TDRPDWQSVMQYVAQIYKYFET 987
Score = 42.7 bits (99), Expect = 0.002
Identities = 100/513 (19%), Positives = 190/513 (37%), Gaps = 66/513 (12%)
Query: 44 GTAASLSKTKSSDDLLAGMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTG 103
G+ + D+ + G T+G T S +P AS T E S+ +
Sbjct: 205 GSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSS 264
Query: 104 TASSTKRSTSTGNKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECD 163
T++ K S + S ++ L + + +K+ + + TA E
Sbjct: 265 TSNPFKSSKCSTAGSSPNSVSELSLASLTEKIQKM-------------EENHHSTAEELQ 311
Query: 164 VRMSK-SKSDNQISDRAALEAKVKDLLTLAKT------KDVEILHLRNE-LRDMRAQLGI 215
+ + S + + A K+ D T+ +T + E L NE L ++ +
Sbjct: 312 ATLQELSDQQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVK 371
Query: 216 NEDHSEGDEK----------------SEKETIMAHQPTDVESTLLQLQEQNTAIREELNQ 259
NE+ + + K E+E ++ Q + +L +++E+N E + +
Sbjct: 372 NEEPTTQEGKIIELEQKCTGILEQGRFEREKLLNIQ-QQLTCSLRKVEEENQGALEMIKR 430
Query: 260 LKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEG--- 316
LK EN L + L LE+ +N + +T + G+L S ++G
Sbjct: 431 LKEENEKLNEFL-----ELERHNNN---MMAKTLEECRVTLEGLKMENGSLKSHLQGEKQ 482
Query: 317 --SAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGI 374
+ +VE E M D L+ C+E+ Q L ++ + SS ++
Sbjct: 483 KATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNELRQELLKANGEIKHVSSLLAKVE 542
Query: 375 PSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSE 434
++ A ++S L ++ + + ++++ T+ EL D + + +
Sbjct: 543 KDYSYLKEICDHQAEQLSRTSL--KLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLH 600
Query: 435 NERLGEEKVILMESLCQQSDKLE--------HFSRQIEYFRSLLDEHHISYVIDEDVKSG 486
N +L E + L +Q LE + E +R + + V+ D+K
Sbjct: 601 NNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVANDIKCE 660
Query: 487 RYMELEQRYMDLAE----NARFEREQLLGVQQH 515
EL L E NAR ++E L VQ H
Sbjct: 661 AQQELRTVKRKLLEEEEKNARLQKE-LGDVQGH 692
>gi|75750466 spectrin domain with coiled-coils 1 NSP5b3a [Homo
sapiens]
Length = 790
Score = 434 bits (1115), Expect = e-121
Identities = 287/783 (36%), Positives = 441/783 (56%), Gaps = 57/783 (7%)
Query: 33 SASTGGKLVKPGTAASLS------KTKSSDDLLAGMAGGVTVTNGVKGKKSTCPSAAPSA 86
+AS+G K K T+ + K SS+D L G T +GV K T + A S
Sbjct: 27 AASSGMKSSKSSTSLAFESRLSRLKRASSEDTLN--KPGSTAASGVVRLKKTATAGAISE 84
Query: 87 SAPAMTTVENKSKISTGTASSTKRSTSTGNKESSSTRERLRERTR-LNQSKKLPSAGQGA 145
E++ + TG ++TKR+ +E S T R R R + +K S+ +
Sbjct: 85 ------LTESRLRSGTGAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSS 138
Query: 146 NDMALAKRSRSRTATECDVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNE 205
N K R+ + +K K +N+ ++AALE++V++LL AK KD EI LR+E
Sbjct: 139 NTPTPTKHLRTPS--------TKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSE 190
Query: 206 LRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENR 265
L+ + + +N + ++ + T ++ P D E + L+E+N ++EL+ L+ ENR
Sbjct: 191 LKKYKEKRTLNAEGTDALGPNVDGTSVS--PGDTEPMIRALEEKNKNFQKELSDLEEENR 248
Query: 266 MLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDL 325
+LK++L L S NSE + S T Q G+ T +
Sbjct: 249 VLKEKLIYLEHS-----PNSEGAASHTGDSSCPTSITQESSFGSPTGNQ----------- 292
Query: 326 LSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSD---------DALDAPSSSESEGIPS 376
+S D + + H N++ S S+V + S D + P SS S S
Sbjct: 293 MSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPFKS 352
Query: 377 IERSRKGSSGNA-SEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSEN 435
+ S GSS N+ SE+S+A LTE+I +MEEN HST+EELQATLQEL+D QQ+ QEL +EN
Sbjct: 353 SKCSTAGSSPNSVSELSLASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAEN 412
Query: 436 ERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDED--VKSGRYMELEQ 493
E+L +EK IL S Q ++ E S++ E +LL E V +E+ + G+ +ELEQ
Sbjct: 413 EKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQER----VKNEEPTTQEGKIIELEQ 468
Query: 494 RYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQK 553
+ + E RFERE+LL +QQ L+ +L+ E++N+ A EMI LKE + + +E E+
Sbjct: 469 KCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERH 528
Query: 554 GKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVR 613
+A TLEE + T+ ++E LK+ L+ EKQK E ++ + + ++Q++L+ R
Sbjct: 529 NNNMMAKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVAR 588
Query: 614 LDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLR 673
+K+ E + L+++L + + +AKVE +Y +E Q E L+ T KL+
Sbjct: 589 AEKDLLELSCNELRQELLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQ 648
Query: 674 SDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIK 733
E + E DMKETIFELED+VEQHRAVKLH+N +IS+LE++V KL++QK D+ER++K
Sbjct: 649 EKASESDAEIKDMKETIFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQKSDLERQLK 708
Query: 734 TLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELE 793
TL ++++EE+ EWR+FQADLQTAVV+ANDIK EAQ+E+ +KR+L E +EKN +L KEL
Sbjct: 709 TLTKQMKEETEEWRRFQADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKNARLQKELG 768
Query: 794 EIK 796
+++
Sbjct: 769 DVQ 771
Score = 30.8 bits (68), Expect = 7.5
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 16/198 (8%)
Query: 714 LENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGD 773
LE+ V++L + + EI L L++ E R A+ A+ D S + GD
Sbjct: 166 LESQVRELLAEAKAKDSEINRLRSELKKYK-EKRTLNAEGTDALGPNVDGTSVSP---GD 221
Query: 774 LKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSST 833
+ + +EKN+ KEL +++ + + +Y ++ + AA G S T
Sbjct: 222 TEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIY-LEHSPNSEGAASHTGDSSCPTSIT 280
Query: 834 --SSEPTPTVKTLIKSFD--------SASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPM 883
SS +PT + D +A + +++ + + LSP A +P
Sbjct: 281 QESSFGSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPS 340
Query: 884 Q-RHSISGPISTSKPLTA 900
+ S S P +SK TA
Sbjct: 341 RPLSSTSNPFKSSKCSTA 358
>gi|75750468 spectrin domain with coiled-coils 1 NSP5a3a [Homo
sapiens]
Length = 709
Score = 421 bits (1083), Expect = e-117
Identities = 266/707 (37%), Positives = 410/707 (57%), Gaps = 43/707 (6%)
Query: 103 GTASSTKRSTSTGNKESSSTRERLRERTR-LNQSKKLPSAGQGANDMALAKRSRSRTATE 161
G ++TKR+ +E S T R R R + +K S+ +N K R+ +
Sbjct: 14 GAFTTTKRTGIPAPREFSVTVSRERSVPRGPSNPRKSVSSPTSSNTPTPTKHLRTPS--- 70
Query: 162 CDVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSE 221
+K K +N+ ++AALE++V++LL AK KD EI LR+EL+ + + +N + ++
Sbjct: 71 -----TKPKQENEGGEKAALESQVRELLAEAKAKDSEINRLRSELKKYKEKRTLNAEGTD 125
Query: 222 GDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQR 281
+ T ++ P D E + L+E+N ++EL+ L+ ENR+LK++L L S
Sbjct: 126 ALGPNVDGTSVS--PGDTEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIYLEHS---- 179
Query: 282 LDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNS 341
NSE + S T Q G+ T + +S D + + H N+
Sbjct: 180 -PNSEGAASHTGDSSCPTSITQESSFGSPTGNQ-----------MSSDIDEYKKNIHGNA 227
Query: 342 MDNLDSECSEVYQPLTSSD---------DALDAPSSSESEGIPSIERSRKGSSGNA-SEV 391
+ S S+V + S D + P SS S S + S GSS N+ SE+
Sbjct: 228 LRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSSTSNPFKSSKCSTAGSSPNSVSEL 287
Query: 392 SVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQ 451
S+A LTE+I +MEEN HST+EELQATLQEL+D QQ+ QEL +ENE+L +EK IL S Q
Sbjct: 288 SLASLTEKIQKMEENHHSTAEELQATLQELSDQQQMVQELTAENEKLVDEKTILETSFHQ 347
Query: 452 QSDKLEHFSRQIEYFRSLLDEHHISYVIDED--VKSGRYMELEQRYMDLAENARFEREQL 509
++ E S++ E +LL E V +E+ + G+ +ELEQ+ + E RFERE+L
Sbjct: 348 HRERAEQLSQENEKLMNLLQER----VKNEEPTTQEGKIIELEQKCTGILEQGRFEREKL 403
Query: 510 LGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATV 569
L +QQ L+ +L+ E++N+ A EMI LKE + + +E E+ +A TLEE + T+
Sbjct: 404 LNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERHNNNMMAKTLEECRVTL 463
Query: 570 ASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQED 629
++E LK+ L+ EKQK E ++ + + ++Q++L+ R +K+ E + L+++
Sbjct: 464 EGLKMENGSLKSHLQGEKQKATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNELRQE 523
Query: 630 LAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKET 689
L + + +AKVE +Y +E Q E L+ T KL+ E + E DMKET
Sbjct: 524 LLKANGEIKHVSSLLAKVEKDYSYLKEICDHQAEQLSRTSLKLQEKASESDAEIKDMKET 583
Query: 690 IFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQF 749
IFELED+VEQHRAVKLH+N +IS+LE++V KL++QK D+ER++KTL ++++EE+ EWR+F
Sbjct: 584 IFELEDQVEQHRAVKLHNNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEETEEWRRF 643
Query: 750 QADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIK 796
QADLQTAVV+ANDIK EAQ+E+ +KR+L E +EKN +L KEL +++
Sbjct: 644 QADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKNARLQKELGDVQ 690
Score = 42.7 bits (99), Expect = 0.002
Identities = 100/513 (19%), Positives = 190/513 (37%), Gaps = 66/513 (12%)
Query: 44 GTAASLSKTKSSDDLLAGMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTG 103
G+ + D+ + G T+G T S +P AS T E S+ +
Sbjct: 205 GSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPSRPLSS 264
Query: 104 TASSTKRSTSTGNKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECD 163
T++ K S + S ++ L + + +K+ + + TA E
Sbjct: 265 TSNPFKSSKCSTAGSSPNSVSELSLASLTEKIQKM-------------EENHHSTAEELQ 311
Query: 164 VRMSK-SKSDNQISDRAALEAKVKDLLTLAKT------KDVEILHLRNE-LRDMRAQLGI 215
+ + S + + A K+ D T+ +T + E L NE L ++ +
Sbjct: 312 ATLQELSDQQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVK 371
Query: 216 NEDHSEGDEK----------------SEKETIMAHQPTDVESTLLQLQEQNTAIREELNQ 259
NE+ + + K E+E ++ Q + +L +++E+N E + +
Sbjct: 372 NEEPTTQEGKIIELEQKCTGILEQGRFEREKLLNIQ-QQLTCSLRKVEEENQGALEMIKR 430
Query: 260 LKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEG--- 316
LK EN L + L LE+ +N + +T + G+L S ++G
Sbjct: 431 LKEENEKLNEFL-----ELERHNNN---MMAKTLEECRVTLEGLKMENGSLKSHLQGEKQ 482
Query: 317 --SAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGI 374
+ +VE E M D L+ C+E+ Q L ++ + SS ++
Sbjct: 483 KATEASAVEQTAESCEVQEMLKVARAEKDLLELSCNELRQELLKANGEIKHVSSLLAKVE 542
Query: 375 PSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSE 434
++ A ++S L ++ + + ++++ T+ EL D + + +
Sbjct: 543 KDYSYLKEICDHQAEQLSRTSL--KLQEKASESDAEIKDMKETIFELEDQVEQHRAVKLH 600
Query: 435 NERLGEEKVILMESLCQQSDKLE--------HFSRQIEYFRSLLDEHHISYVIDEDVKSG 486
N +L E + L +Q LE + E +R + + V+ D+K
Sbjct: 601 NNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVANDIKCE 660
Query: 487 RYMELEQRYMDLAE----NARFEREQLLGVQQH 515
EL L E NAR ++E L VQ H
Sbjct: 661 AQQELRTVKRKLLEEEEKNARLQKE-LGDVQGH 692
Score = 30.8 bits (68), Expect = 7.5
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 16/198 (8%)
Query: 714 LENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGD 773
LE+ V++L + + EI L L++ E R A+ A+ D S + GD
Sbjct: 85 LESQVRELLAEAKAKDSEINRLRSELKKYK-EKRTLNAEGTDALGPNVDGTSVSP---GD 140
Query: 774 LKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSST 833
+ + +EKN+ KEL +++ + + +Y ++ + AA G S T
Sbjct: 141 TEPMIRALEEKNKNFQKELSDLEEENRVLKEKLIY-LEHSPNSEGAASHTGDSSCPTSIT 199
Query: 834 --SSEPTPTVKTLIKSFD--------SASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPM 883
SS +PT + D +A + +++ + + LSP A +P
Sbjct: 200 QESSFGSPTGNQMSSDIDEYKKNIHGNALRTSGSSSSDVTKASLSPDASDFEHITAETPS 259
Query: 884 Q-RHSISGPISTSKPLTA 900
+ S S P +SK TA
Sbjct: 260 RPLSSTSNPFKSSKCSTA 277
>gi|19913396 smoothelin isoform b [Homo sapiens]
Length = 915
Score = 110 bits (275), Expect = 7e-24
Identities = 69/201 (34%), Positives = 104/201 (51%), Gaps = 23/201 (11%)
Query: 935 MESAKTLSVSRRSSEEVKRDISAQEGASP--ASLMAMGTTSPQ-----LSLSSSPTASVT 987
M KT S S SS+++ ++ ASP SL A+ + + S P S +
Sbjct: 703 MMQTKTFS-SSSSSKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSAS 761
Query: 988 PTTRSRIREERKD--------PLSALAREYGGSKRNA------LLKWCQKKTEGYQNIDI 1033
++ I + K+ P +A+ R NA LL WC+ KT GY+++DI
Sbjct: 762 QARKAMIEKLEKEGAAGSPGGPRAAVQRSTSFGVPNANSIKQMLLDWCRAKTRGYEHVDI 821
Query: 1034 TNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAES-VGIKSTLDINE 1092
NFSSSW+DG+AFCAL+H + P Y +L+ Q++R+NF +AF +AE+ LD +
Sbjct: 822 QNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTED 881
Query: 1093 MVRTERPDWQNVMLYVTAIYK 1113
MVR PDW+ V Y+ Y+
Sbjct: 882 MVRLREPDWKCVYTYIQEFYR 902
Score = 32.7 bits (73), Expect = 2.0
Identities = 59/303 (19%), Positives = 107/303 (35%), Gaps = 44/303 (14%)
Query: 714 LENTVKKLQDQKHDMEREI---KTLHRRLREESAEW---RQFQADLQTAVV-IANDIKSE 766
+ + +++LQ Q+ + E E K ++ W +Q +A+ + A+ +A + E
Sbjct: 30 IRSAIRELQRQELEREEEALASKRFRAERQDNKENWLHSQQREAEQRAALARLAGQL--E 87
Query: 767 AQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMG 826
+ ++ +L L A E E+ + R QE E + + + + + G
Sbjct: 88 SMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQEIEAATLAGRLYSGRPNSGSREDSKG 147
Query: 827 LS---------------RRSSTSSEPTPTVK---------TLIKSFDSASQVPNPAAAAI 862
L+ + + S+PTPT + TL+ S +PA+ +
Sbjct: 148 LAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSS 207
Query: 863 PRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSS 922
TP SP P P A + P P S + +P E +
Sbjct: 208 SPTPASPEPPLEP--AEAQCLTAEVPGSPEPPPSPPKTTSPEPQESPTLPSTEGQVVNKL 265
Query: 923 ASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEGASPASLMAMGTTSPQLSLSSSP 982
S P P S +R S+ + D++ SL + P + S+P
Sbjct: 266 LSGPKETPAAQ--------SPTRGPSDTKRADVAGPRPCQ-RSLSVLSPRQPAQNRESTP 316
Query: 983 TAS 985
AS
Sbjct: 317 LAS 319
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 107 bits (266), Expect = 8e-23
Identities = 109/444 (24%), Positives = 174/444 (39%), Gaps = 68/444 (15%)
Query: 712 SDLENTVKKLQDQKHDMEREI---KTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQ 768
++L+ L + K + +RE + L++E E + Q + KSE +
Sbjct: 82 AELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEETKSEPK 141
Query: 769 EEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMN--------AVERDLAA 820
E A+EK L E ++ + ++ + E G+ + + VE + A
Sbjct: 142 E-----------AEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAK 190
Query: 821 LRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNPAAAAIPRTPLSPSPMK---TPPA 877
+R S+EP +S V A A P+ P K A
Sbjct: 191 TASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEA 250
Query: 878 AAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMES 937
A + + P S S+ +K P G + S P P P E
Sbjct: 251 DAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIP---------SSPEEWPESPTGEG 301
Query: 938 AKTLSVSRRSSEEVKRDISAQEGASPASLMAMGTTSPQL---SLSSSPTASVTPTTR--- 991
S++ + D A SP++ + + PQ S SS P R
Sbjct: 302 HNL------STDGLGPDCVASGQTSPSASESSPSDVPQSPPESPSSGEKKEKAPERRVSA 355
Query: 992 -SRIREERKDPLSALAREYGGSK--------------------RNALLKWCQKKTEGYQN 1030
+R R R A+ ++GG+ +N LL+WC+ T+ Y++
Sbjct: 356 PARPRGPRAQNRKAIVDKFGGAASGPTALFRNTKAAGAAIGGVKNMLLEWCRAMTKKYEH 415
Query: 1031 IDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAESVG-IKSTLD 1089
+DI NFSSSW+ G+AFCAL+H + P Y EL+ +R NF LAF AE + LD
Sbjct: 416 VDIQNFSSSWSSGMAFCALIHKFFPDAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLD 475
Query: 1090 INEMVRTERPDWQNVMLYVTAIYK 1113
+++MVR PD + V Y+ +Y+
Sbjct: 476 VDDMVRLAVPDSKCVYTYIQELYR 499
Score = 34.7 bits (78), Expect = 0.52
Identities = 43/193 (22%), Positives = 77/193 (39%), Gaps = 18/193 (9%)
Query: 511 GVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVA 570
G+ L ++ E+Q G ++ +++ + E++ + + K
Sbjct: 79 GMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKE-DGEKEETTVGSQEMTGRKEETK 137
Query: 571 SDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDL 630
S+ E ++ L +EKQK E + SG K+D D++K E A+ +ED
Sbjct: 138 SEPKEAEEKESTLASEKQKAEEKEAKPESGQKADAN--------DRDKPEPKATVEEED- 188
Query: 631 AHTRNDANRLQDAIAKVEDEYRAFQEEAKKQ-----IEDLNMTLEKLRSDLDEKE---TE 682
A T + Q E + +A EEAK + +ED K +E + E
Sbjct: 189 AKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKE 248
Query: 683 RSDMKETIFELED 695
+D KE + E+
Sbjct: 249 EADAKEEAEDAEE 261
>gi|19913398 smoothelin isoform a [Homo sapiens]
Length = 940
Score = 104 bits (259), Expect = 5e-22
Identities = 66/190 (34%), Positives = 99/190 (52%), Gaps = 23/190 (12%)
Query: 935 MESAKTLSVSRRSSEEVKRDISAQEGASP--ASLMAMGTTSPQ-----LSLSSSPTASVT 987
M KT S S SS+++ ++ ASP SL A+ + + S P S +
Sbjct: 703 MMQTKTFS-SSSSSKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSAS 761
Query: 988 PTTRSRIREERKD--------PLSALAREYGGSKRNA------LLKWCQKKTEGYQNIDI 1033
++ I + K+ P +A+ R NA LL WC+ KT GY+++DI
Sbjct: 762 QARKAMIEKLEKEGAAGSPGGPRAAVQRSTSFGVPNANSIKQMLLDWCRAKTRGYEHVDI 821
Query: 1034 TNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAES-VGIKSTLDINE 1092
NFSSSW+DG+AFCAL+H + P Y +L+ Q++R+NF +AF +AE+ LD +
Sbjct: 822 QNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAETHADCPQLLDTED 881
Query: 1093 MVRTERPDWQ 1102
MVR PDW+
Sbjct: 882 MVRLREPDWK 891
Score = 32.7 bits (73), Expect = 2.0
Identities = 59/303 (19%), Positives = 104/303 (34%), Gaps = 44/303 (14%)
Query: 714 LENTVKKLQDQKHDMEREI---KTLHRRLREESAEW---RQFQADLQTAVV-IANDIKSE 766
+ + +++LQ Q+ + E E K ++ W +Q +A+ + A+ +A + E
Sbjct: 30 IRSAIRELQRQELEREEEALASKRFRAERQDNKENWLHSQQREAEQRAALARLAGQL--E 87
Query: 767 AQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMG 826
+ ++ +L L A E E+ + R QE E + + + + + G
Sbjct: 88 SMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQEIEAATLAGRLYSGRPNSGSREDSKG 147
Query: 827 LS---------------RRSSTSSEPTPTVK---------TLIKSFDSASQVPNPAAAAI 862
L+ + + S+PTPT + TL+ S +PA+ +
Sbjct: 148 LAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSS 207
Query: 863 PRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSS 922
TP SP P P A + P P S + +P E +
Sbjct: 208 SPTPASPEPPLEP--AEAQCLTAEVPGSPEPPPSPPKTTSPEPQESPTLPSTEGQVVNKL 265
Query: 923 ASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEGASPASLMAMGTTSPQLSLSSSP 982
S P P + R + KR A SL + P + S+P
Sbjct: 266 LSGPKETPAAQS---------PHRGPSDTKRADVAGPRPCQRSLSVLSPRQPAQNRESTP 316
Query: 983 TAS 985
AS
Sbjct: 317 LAS 319
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 102 bits (253), Expect = 3e-21
Identities = 147/766 (19%), Positives = 310/766 (40%), Gaps = 97/766 (12%)
Query: 116 NKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQI 175
N + S R+ L ER + + L + A ++ K +E +VR+ K + Q
Sbjct: 994 NNKLSKERKLLEERIS-DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ- 1051
Query: 176 SDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEG------DEKSEKE 229
LE + L A +I L+ ++ +++ QL E+ + DE ++K
Sbjct: 1052 ----ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 230 TIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLF 289
+ + ++E + LQE + R N+ + + R L + L AL LE LD++
Sbjct: 1108 NALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST---- 1162
Query: 290 GYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSEC 349
+ E+ + + T+ + DE T H + + +
Sbjct: 1163 ---ATQQELRAKREQEV--TVLKK-------------ALDEET---RSHEAQVQEMRQKH 1201
Query: 350 SEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHS 409
++ + LT + ++ + ++E+ +G + L + ++E +
Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE-----LRVLGQAKQEVEHKKKK 1256
Query: 410 TSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSL 469
++Q + +D ++ ELN + +L E + L + K ++ + S
Sbjct: 1257 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
Query: 470 LDEHHISYVIDEDVK-----SGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAE 524
L + ++ E+ + S + +LE+ L + E E +++H+S
Sbjct: 1317 LQD--TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
Query: 525 QDNKEAQEM---IGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKA 581
K+ Q+ + AL+E ++ IE+ + AA ++ + T Q E++ L
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 582 QLENEKQKVAELYSIHNSGDK------------SDIQDLLESVRLDKE-KAETLASSLQE 628
L+N++Q V+ L D+ +D +D E+ +KE KA +LA +L+E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 629 DLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKE 688
L ++ + + +A E+ +D+ + +L ET+ +MK
Sbjct: 1495 AL--------EAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1546
Query: 689 TIFELEDEVEQHRAVKL-------------HDNLIISDLENTVKK--LQDQKHDMEREIK 733
+ ELEDE++ KL +L D +N K+ LQ Q H+ E E++
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE 1606
Query: 734 TLHRRLREESAEWRQFQADLQTAVVIANDI---KSEAQEEIGDLKRRLHEAQEKNEKLTK 790
++ +A ++ + DL+ + A+ + EA +++ L+ ++ + Q + E
Sbjct: 1607 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARA 1666
Query: 791 ELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSE 836
+EI + +E E+ ++E DL L++ + + R+ ++
Sbjct: 1667 SRDEIFATAKENEK-----KAKSLEADLMQLQEDLAAAERARKQAD 1707
Score = 99.0 bits (245), Expect = 2e-20
Identities = 165/775 (21%), Positives = 316/775 (40%), Gaps = 98/775 (12%)
Query: 124 ERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAALEA 183
+ + E T + K A N L K + + +K + +++ + LEA
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK---KKKLEA 1259
Query: 184 KVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTL 243
+V++L + K D E R EL D +L NE S +E E DV S
Sbjct: 1260 QVQELQS--KCSDGE--RARAELNDKVHKLQ-NEVESVTGMLNEAEGKAIKLAKDVASLS 1314
Query: 244 LQLQEQNTAIREELNQLKNEN---RMLKDRLNALGFSLEQRLDNSEKLFGYQS-LSPEIT 299
QLQ+ ++EE Q N + R L++ N+L L++ ++ + L + S L+ +++
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
Query: 300 PDNQS--DGGGTLTSSVEGSA--PGSVEDLLSQDENTLMDHQHSNSMDN-LDSECSEVYQ 354
+ D T+ + EG +E+L Q E + N L E ++
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 355 PLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEEL 414
L + + + + + + SS A E A R + E S + L
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR--EKETKALSLARAL 1492
Query: 415 QATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHH 474
+ L+ +L++ + L +E E L K + +++ + Q+E ++ L+E
Sbjct: 1493 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1552
Query: 475 ISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMI 534
ED K + LE L +FER+ L+ ++ N+E +
Sbjct: 1553 DELQATEDAK----LRLEVNMQAL--KGQFERD------------LQARDEQNEEKRRQ- 1593
Query: 535 GALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIE--------------MNRLK 580
L+ + H E +E E+K +A AA ++ + + +++ + +L+
Sbjct: 1594 --LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 581 AQ-------LENEKQKVAELYSIHNSGDKS---------DIQDLLESVRLDKEKAETLAS 624
AQ LE+ + E+++ +K +Q+ L + +++A+
Sbjct: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
Query: 625 SLQEDLAHTRNDANRLQDA-------IAKVEDEYRAFQ----------EEAKKQIEDLNM 667
L E+LA + + N LQD IA++E+E Q +A +Q E L+
Sbjct: 1712 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSN 1771
Query: 668 TLEKLRSDLDEKETERSDMKETIFELEDEV-EQHRAVKLHDNLIISDLENTVKKLQDQKH 726
L RS + E+ R ++ EL ++ E AVK I+ LE + +L++Q
Sbjct: 1772 ELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1831
Query: 727 DMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQE---EIGDLKRRLHEAQE 783
RE + + L+++ + ++ ++ +A K +A++ + LKR+L EA+E
Sbjct: 1832 QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEE 1891
Query: 784 KNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPT 838
+++++ RK + E A+ R++ AL+ L R + TS P+
Sbjct: 1892 ESQRI-----NANRRKLQRELDEATESNEAMGREVNALKS--KLRRGNETSFVPS 1939
Score = 84.0 bits (206), Expect = 7e-16
Identities = 98/475 (20%), Positives = 208/475 (43%), Gaps = 66/475 (13%)
Query: 399 RIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSD---K 455
++ + EE + +ELQ T + + +EL ++ +L EEK +L E L +++ +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 456 LEHFSRQIEYFRSLLDE--HHISYVIDEDVKSGRYMELE-----QRYMDLAENARFE--- 505
E ++ + L+E H + ++E+ G+ ++ E Q+ +DL E E
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 506 REQL--------LGVQQHLSNTLKMAEQDNKEAQEMIGALKER-SHHMERIIESEQKGK- 555
R++L +++ L M +Q+NK ++E L+ER S + E E+K K
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKN 1024
Query: 556 --------AALAATLEEYKATVASDQIEMNRLKAQLENE----KQKVAELYSIHNSGDKS 603
++ + LE + E+ +LK +LE + +++A+L ++
Sbjct: 1025 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL--------QA 1076
Query: 604 DIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVE------DEYRAFQEE 657
I +L + +E+ + + L +++A N ++++ + D RA + +
Sbjct: 1077 QIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1136
Query: 658 AKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENT 717
A+KQ DL LE L+++L++ + +E + E EV ++ L+
Sbjct: 1137 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----------TVLKKALDEE 1186
Query: 718 VKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRR 777
+ + Q +M ++ L E+ ++++ +A+L ++ E+ L +
Sbjct: 1187 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1246
Query: 778 LHEAQEKNEKLTKELEEIKSRKQEEERGR------VYNYMNAVERDLAALRQGMG 826
E + K +KL +++E++S+ + ER R V+ N VE L + G
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1301
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 102 bits (253), Expect = 3e-21
Identities = 147/766 (19%), Positives = 310/766 (40%), Gaps = 97/766 (12%)
Query: 116 NKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQI 175
N + S R+ L ER + + L + A ++ K +E +VR+ K + Q
Sbjct: 1001 NNKLSKERKLLEERIS-DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ- 1058
Query: 176 SDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEG------DEKSEKE 229
LE + L A +I L+ ++ +++ QL E+ + DE ++K
Sbjct: 1059 ----ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 230 TIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLF 289
+ + ++E + LQE + R N+ + + R L + L AL LE LD++
Sbjct: 1115 NALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST---- 1169
Query: 290 GYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSEC 349
+ E+ + + T+ + DE T H + + +
Sbjct: 1170 ---ATQQELRAKREQEV--TVLKK-------------ALDEET---RSHEAQVQEMRQKH 1208
Query: 350 SEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHS 409
++ + LT + ++ + ++E+ +G + L + ++E +
Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE-----LRVLGQAKQEVEHKKKK 1263
Query: 410 TSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSL 469
++Q + +D ++ ELN + +L E + L + K ++ + S
Sbjct: 1264 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 470 LDEHHISYVIDEDVK-----SGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAE 524
L + ++ E+ + S + +LE+ L + E E +++H+S
Sbjct: 1324 LQD--TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1381
Query: 525 QDNKEAQEM---IGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKA 581
K+ Q+ + AL+E ++ IE+ + AA ++ + T Q E++ L
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 582 QLENEKQKVAELYSIHNSGDK------------SDIQDLLESVRLDKE-KAETLASSLQE 628
L+N++Q V+ L D+ +D +D E+ +KE KA +LA +L+E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 629 DLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKE 688
L ++ + + +A E+ +D+ + +L ET+ +MK
Sbjct: 1502 AL--------EAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1553
Query: 689 TIFELEDEVEQHRAVKL-------------HDNLIISDLENTVKK--LQDQKHDMEREIK 733
+ ELEDE++ KL +L D +N K+ LQ Q H+ E E++
Sbjct: 1554 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE 1613
Query: 734 TLHRRLREESAEWRQFQADLQTAVVIANDI---KSEAQEEIGDLKRRLHEAQEKNEKLTK 790
++ +A ++ + DL+ + A+ + EA +++ L+ ++ + Q + E
Sbjct: 1614 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARA 1673
Query: 791 ELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSE 836
+EI + +E E+ ++E DL L++ + + R+ ++
Sbjct: 1674 SRDEIFATAKENEK-----KAKSLEADLMQLQEDLAAAERARKQAD 1714
Score = 99.0 bits (245), Expect = 2e-20
Identities = 165/775 (21%), Positives = 316/775 (40%), Gaps = 98/775 (12%)
Query: 124 ERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAALEA 183
+ + E T + K A N L K + + +K + +++ + LEA
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK---KKKLEA 1266
Query: 184 KVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTL 243
+V++L + K D E R EL D +L NE S +E E DV S
Sbjct: 1267 QVQELQS--KCSDGE--RARAELNDKVHKLQ-NEVESVTGMLNEAEGKAIKLAKDVASLS 1321
Query: 244 LQLQEQNTAIREELNQLKNEN---RMLKDRLNALGFSLEQRLDNSEKLFGYQS-LSPEIT 299
QLQ+ ++EE Q N + R L++ N+L L++ ++ + L + S L+ +++
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1381
Query: 300 PDNQS--DGGGTLTSSVEGSA--PGSVEDLLSQDENTLMDHQHSNSMDN-LDSECSEVYQ 354
+ D T+ + EG +E+L Q E + N L E ++
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 355 PLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEEL 414
L + + + + + + SS A E A R + E S + L
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR--EKETKALSLARAL 1499
Query: 415 QATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHH 474
+ L+ +L++ + L +E E L K + +++ + Q+E ++ L+E
Sbjct: 1500 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1559
Query: 475 ISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMI 534
ED K + LE L +FER+ L+ ++ N+E +
Sbjct: 1560 DELQATEDAK----LRLEVNMQAL--KGQFERD------------LQARDEQNEEKRRQ- 1600
Query: 535 GALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIE--------------MNRLK 580
L+ + H E +E E+K +A AA ++ + + +++ + +L+
Sbjct: 1601 --LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 581 AQ-------LENEKQKVAELYSIHNSGDKS---------DIQDLLESVRLDKEKAETLAS 624
AQ LE+ + E+++ +K +Q+ L + +++A+
Sbjct: 1659 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1718
Query: 625 SLQEDLAHTRNDANRLQDA-------IAKVEDEYRAFQ----------EEAKKQIEDLNM 667
L E+LA + + N LQD IA++E+E Q +A +Q E L+
Sbjct: 1719 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSN 1778
Query: 668 TLEKLRSDLDEKETERSDMKETIFELEDEV-EQHRAVKLHDNLIISDLENTVKKLQDQKH 726
L RS + E+ R ++ EL ++ E AVK I+ LE + +L++Q
Sbjct: 1779 ELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1838
Query: 727 DMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQE---EIGDLKRRLHEAQE 783
RE + + L+++ + ++ ++ +A K +A++ + LKR+L EA+E
Sbjct: 1839 QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEE 1898
Query: 784 KNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPT 838
+++++ RK + E A+ R++ AL+ L R + TS P+
Sbjct: 1899 ESQRI-----NANRRKLQRELDEATESNEAMGREVNALKS--KLRRGNETSFVPS 1946
Score = 84.0 bits (206), Expect = 7e-16
Identities = 98/475 (20%), Positives = 208/475 (43%), Gaps = 66/475 (13%)
Query: 399 RIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSD---K 455
++ + EE + +ELQ T + + +EL ++ +L EEK +L E L +++ +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 456 LEHFSRQIEYFRSLLDE--HHISYVIDEDVKSGRYMELE-----QRYMDLAENARFE--- 505
E ++ + L+E H + ++E+ G+ ++ E Q+ +DL E E
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 506 REQL--------LGVQQHLSNTLKMAEQDNKEAQEMIGALKER-SHHMERIIESEQKGK- 555
R++L +++ L M +Q+NK ++E L+ER S + E E+K K
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKN 1031
Query: 556 --------AALAATLEEYKATVASDQIEMNRLKAQLENE----KQKVAELYSIHNSGDKS 603
++ + LE + E+ +LK +LE + +++A+L ++
Sbjct: 1032 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL--------QA 1083
Query: 604 DIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVE------DEYRAFQEE 657
I +L + +E+ + + L +++A N ++++ + D RA + +
Sbjct: 1084 QIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1143
Query: 658 AKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENT 717
A+KQ DL LE L+++L++ + +E + E EV ++ L+
Sbjct: 1144 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----------TVLKKALDEE 1193
Query: 718 VKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRR 777
+ + Q +M ++ L E+ ++++ +A+L ++ E+ L +
Sbjct: 1194 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1253
Query: 778 LHEAQEKNEKLTKELEEIKSRKQEEERGR------VYNYMNAVERDLAALRQGMG 826
E + K +KL +++E++S+ + ER R V+ N VE L + G
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1308
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 102 bits (253), Expect = 3e-21
Identities = 147/766 (19%), Positives = 310/766 (40%), Gaps = 97/766 (12%)
Query: 116 NKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQI 175
N + S R+ L ER + + L + A ++ K +E +VR+ K + Q
Sbjct: 1001 NNKLSKERKLLEERIS-DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ- 1058
Query: 176 SDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEG------DEKSEKE 229
LE + L A +I L+ ++ +++ QL E+ + DE ++K
Sbjct: 1059 ----ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114
Query: 230 TIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLF 289
+ + ++E + LQE + R N+ + + R L + L AL LE LD++
Sbjct: 1115 NALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST---- 1169
Query: 290 GYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSEC 349
+ E+ + + T+ + DE T H + + +
Sbjct: 1170 ---ATQQELRAKREQEV--TVLKK-------------ALDEET---RSHEAQVQEMRQKH 1208
Query: 350 SEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHS 409
++ + LT + ++ + ++E+ +G + L + ++E +
Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE-----LRVLGQAKQEVEHKKKK 1263
Query: 410 TSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSL 469
++Q + +D ++ ELN + +L E + L + K ++ + S
Sbjct: 1264 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 470 LDEHHISYVIDEDVK-----SGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAE 524
L + ++ E+ + S + +LE+ L + E E +++H+S
Sbjct: 1324 LQD--TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1381
Query: 525 QDNKEAQEM---IGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKA 581
K+ Q+ + AL+E ++ IE+ + AA ++ + T Q E++ L
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 582 QLENEKQKVAELYSIHNSGDK------------SDIQDLLESVRLDKE-KAETLASSLQE 628
L+N++Q V+ L D+ +D +D E+ +KE KA +LA +L+E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 629 DLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKE 688
L ++ + + +A E+ +D+ + +L ET+ +MK
Sbjct: 1502 AL--------EAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1553
Query: 689 TIFELEDEVEQHRAVKL-------------HDNLIISDLENTVKK--LQDQKHDMEREIK 733
+ ELEDE++ KL +L D +N K+ LQ Q H+ E E++
Sbjct: 1554 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE 1613
Query: 734 TLHRRLREESAEWRQFQADLQTAVVIANDI---KSEAQEEIGDLKRRLHEAQEKNEKLTK 790
++ +A ++ + DL+ + A+ + EA +++ L+ ++ + Q + E
Sbjct: 1614 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARA 1673
Query: 791 ELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSE 836
+EI + +E E+ ++E DL L++ + + R+ ++
Sbjct: 1674 SRDEIFATAKENEK-----KAKSLEADLMQLQEDLAAAERARKQAD 1714
Score = 98.2 bits (243), Expect = 4e-20
Identities = 162/757 (21%), Positives = 310/757 (40%), Gaps = 100/757 (13%)
Query: 124 ERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAALEA 183
+ + E T + K A N L K + + +K + +++ + LEA
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK---KKKLEA 1266
Query: 184 KVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTL 243
+V++L + K D E R EL D +L NE S +E E DV S
Sbjct: 1267 QVQELQS--KCSDGE--RARAELNDKVHKLQ-NEVESVTGMLNEAEGKAIKLAKDVASLS 1321
Query: 244 LQLQEQNTAIREELNQLKNEN---RMLKDRLNALGFSLEQRLDNSEKLFGYQS-LSPEIT 299
QLQ+ ++EE Q N + R L++ N+L L++ ++ + L + S L+ +++
Sbjct: 1322 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1381
Query: 300 PDNQS--DGGGTLTSSVEGSA--PGSVEDLLSQDENTLMDHQHSNSMDN-LDSECSEVYQ 354
+ D T+ + EG +E+L Q E + N L E ++
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 355 PLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEEL 414
L + + + + + + SS A E A R + E S + L
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR--EKETKALSLARAL 1499
Query: 415 QATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHH 474
+ L+ +L++ + L +E E L K + +++ + Q+E ++ L+E
Sbjct: 1500 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1559
Query: 475 ISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMI 534
ED K + LE L +FER+ L+ ++ N+E +
Sbjct: 1560 DELQATEDAK----LRLEVNMQAL--KGQFERD------------LQARDEQNEEKRRQ- 1600
Query: 535 GALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIE--------------MNRLK 580
L+ + H E +E E+K +A AA ++ + + +++ + +L+
Sbjct: 1601 --LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 581 AQ-------LENEKQKVAELYSIHNSGDKS---------DIQDLLESVRLDKEKAETLAS 624
AQ LE+ + E+++ +K +Q+ L + +++A+
Sbjct: 1659 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1718
Query: 625 SLQEDLAHTRNDANRLQDA-------IAKVEDEYRAFQ----------EEAKKQIEDLNM 667
L E+LA + + N LQD IA++E+E Q +A +Q E L+
Sbjct: 1719 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSN 1778
Query: 668 TLEKLRSDLDEKETERSDMKETIFELEDEV-EQHRAVKLHDNLIISDLENTVKKLQDQKH 726
L RS + E+ R ++ EL ++ E AVK I+ LE + +L++Q
Sbjct: 1779 ELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1838
Query: 727 DMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQE---EIGDLKRRLHEAQE 783
RE + + L+++ + ++ ++ +A K +A++ + LKR+L EA+E
Sbjct: 1839 QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEE 1898
Query: 784 KNE-------KLTKELEEIKSRKQEEERGRVYNYMNA 813
+++ KL +EL+E + + E GR N + +
Sbjct: 1899 ESQRINANRRKLQRELDE--ATESNEAMGREVNALKS 1933
Score = 95.5 bits (236), Expect = 2e-19
Identities = 143/679 (21%), Positives = 284/679 (41%), Gaps = 97/679 (14%)
Query: 167 SKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKS 226
++ K+ D A+L ++++D L + + + L++ +LR + + +D + +E
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD-EEME 1364
Query: 227 EKETIMAHQPT-------------DVESTLLQLQEQNTAIREELNQLKN---ENRMLKDR 270
K+ + H T D ST+ L+E ++E+ L E D+
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424
Query: 271 LNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDE 330
L L+Q LD+ + DNQ L S++E + LL++++
Sbjct: 1425 LEKTKNRLQQELDDLV-----------VDLDNQRQ----LVSNLE-KKQRKFDQLLAEEK 1468
Query: 331 NTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASE 390
N + ++++ D ++E E S AL+ ++ E +ER+ K +
Sbjct: 1469 N--ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE----LERTNKMLKAEMED 1522
Query: 391 V--SVACLTERIHQMEENQHSTS---EELQATLQELADLQQITQELNSENE-----RLGE 440
+ S + + +H++E+++ + EE++ L+EL D Q T++ E G+
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1582
Query: 441 EKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAE 500
+ L Q +K RQ+ + + L++ + K +LE DL
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK----KLEGDLKDLEL 1638
Query: 501 NARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAA 560
A + G ++ + K+ Q +E+ A R E+E+K K+ L A
Sbjct: 1639 QAD---SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS-LEA 1694
Query: 561 TLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAE 620
L + + +A+ + R + Q + EK+++AE + SG ++ +QD +K + E
Sbjct: 1695 DLMQLQEDLAAAE----RARKQADLEKEELAEELASSLSG-RNALQD-------EKRRLE 1742
Query: 621 TLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEE-------------AKKQIEDLNM 667
+ L+E+L + + + D + K + E A++Q+E N
Sbjct: 1743 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN- 1801
Query: 668 TLEKLRSDLDEKE-TERSDMKETIF-------ELEDEVEQHRAVKLHDNLIISDLENTVK 719
++LRS L E E +S K TI +LE++VEQ K + + +K
Sbjct: 1802 --KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1859
Query: 720 KLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLH 779
++ Q D + + + + +A +Q + L+ A + I + ++ L+R L
Sbjct: 1860 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK----LQRELD 1915
Query: 780 EAQEKNEKLTKELEEIKSR 798
EA E NE + +E+ +KS+
Sbjct: 1916 EATESNEAMGREVNALKSK 1934
Score = 84.0 bits (206), Expect = 7e-16
Identities = 98/475 (20%), Positives = 208/475 (43%), Gaps = 66/475 (13%)
Query: 399 RIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSD---K 455
++ + EE + +ELQ T + + +EL ++ +L EEK +L E L +++ +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 456 LEHFSRQIEYFRSLLDE--HHISYVIDEDVKSGRYMELE-----QRYMDLAENARFE--- 505
E ++ + L+E H + ++E+ G+ ++ E Q+ +DL E E
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 506 REQL--------LGVQQHLSNTLKMAEQDNKEAQEMIGALKER-SHHMERIIESEQKGK- 555
R++L +++ L M +Q+NK ++E L+ER S + E E+K K
Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKN 1031
Query: 556 --------AALAATLEEYKATVASDQIEMNRLKAQLENE----KQKVAELYSIHNSGDKS 603
++ + LE + E+ +LK +LE + +++A+L ++
Sbjct: 1032 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL--------QA 1083
Query: 604 DIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVE------DEYRAFQEE 657
I +L + +E+ + + L +++A N ++++ + D RA + +
Sbjct: 1084 QIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1143
Query: 658 AKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENT 717
A+KQ DL LE L+++L++ + +E + E EV ++ L+
Sbjct: 1144 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----------TVLKKALDEE 1193
Query: 718 VKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRR 777
+ + Q +M ++ L E+ ++++ +A+L ++ E+ L +
Sbjct: 1194 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1253
Query: 778 LHEAQEKNEKLTKELEEIKSRKQEEERGR------VYNYMNAVERDLAALRQGMG 826
E + K +KL +++E++S+ + ER R V+ N VE L + G
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1308
Score = 72.8 bits (177), Expect = 2e-12
Identities = 143/685 (20%), Positives = 280/685 (40%), Gaps = 103/685 (15%)
Query: 99 KISTGTASSTKRSTSTGNKESSSTRERLRERTRLNQSKKLPSAGQGANDMAL-AKRSRSR 157
K++ AS + + T TR++L T+L Q ++ ++ Q D + AK++ R
Sbjct: 1312 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1371
Query: 158 TATECDVRMSKSKSDNQ--ISDRAALEAKVKDLLTLAKTKDVEILHLRNE--------LR 207
+ ++++S SK Q S ALE K K++E L + E L
Sbjct: 1372 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRF-----QKEIENLTQQYEEKAAAYDKLE 1426
Query: 208 DMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIR--EELNQLKNENR 265
+ +L D D ++++ + + + L +E+N + + +E ++ + E R
Sbjct: 1427 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1486
Query: 266 MLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDL 325
+ + +L +LE+ L+ E+L +EDL
Sbjct: 1487 EKETKALSLARALEEALEAKEEL-----------------------ERTNKMLKAEMEDL 1523
Query: 326 LSQDENTLMD-HQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGS 384
+S ++ + H+ S L+++ E+ L +D L A ++ +++ + KG
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ-ALKGQ 1582
Query: 385 SGNASEVSVACLTERIHQMEENQHSTSEELQATLQELA-----------DLQQITQELNS 433
+ E+ Q++ H EL+ ++ A DL+ + EL +
Sbjct: 1583 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL--ELQA 1640
Query: 434 ENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELE- 492
++ G E+ I + L + +++ F R++E R+ DE I E+ K + +E +
Sbjct: 1641 DSAIKGREEAI--KQLRKLQAQMKDFQRELEDARASRDE--IFATAKENEKKAKSLEADL 1696
Query: 493 ---QRYMDLAENAR----FEREQLLGVQQHLSNTL--KMAEQDNKEAQEMIGA-----LK 538
Q + AE AR E+E+L + L+++L + A QD K E A L+
Sbjct: 1697 MQLQEDLAAAERARKQADLEKEELA---EELASSLSGRNALQDEKRRLEARIAQLEEELE 1753
Query: 539 ERSHHMERIIESEQKGKAA---LAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYS 595
E +ME + + +K L+ L ++T ++ +L+ Q + + K+ E+
Sbjct: 1754 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG 1813
Query: 596 IHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQ 655
S KS I L + +E+ E A Q + +L++ + +VEDE R
Sbjct: 1814 AVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE-RKMA 1872
Query: 656 EEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLE 715
E+ K+Q E N +++L+ L+E E E + +L+ E+++
Sbjct: 1873 EQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE---------------- 1916
Query: 716 NTVKKLQDQKHDMEREIKTLHRRLR 740
+ M RE+ L +LR
Sbjct: 1917 -----ATESNEAMGREVNALKSKLR 1936
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 102 bits (253), Expect = 3e-21
Identities = 147/766 (19%), Positives = 310/766 (40%), Gaps = 97/766 (12%)
Query: 116 NKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQI 175
N + S R+ L ER + + L + A ++ K +E +VR+ K + Q
Sbjct: 994 NNKLSKERKLLEERIS-DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ- 1051
Query: 176 SDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEG------DEKSEKE 229
LE + L A +I L+ ++ +++ QL E+ + DE ++K
Sbjct: 1052 ----ELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
Query: 230 TIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLF 289
+ + ++E + LQE + R N+ + + R L + L AL LE LD++
Sbjct: 1108 NALK-KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST---- 1162
Query: 290 GYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSEC 349
+ E+ + + T+ + DE T H + + +
Sbjct: 1163 ---ATQQELRAKREQEV--TVLKK-------------ALDEET---RSHEAQVQEMRQKH 1201
Query: 350 SEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHS 409
++ + LT + ++ + ++E+ +G + L + ++E +
Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGE-----LRVLGQAKQEVEHKKKK 1256
Query: 410 TSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSL 469
++Q + +D ++ ELN + +L E + L + K ++ + S
Sbjct: 1257 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
Query: 470 LDEHHISYVIDEDVK-----SGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAE 524
L + ++ E+ + S + +LE+ L + E E +++H+S
Sbjct: 1317 LQD--TQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
Query: 525 QDNKEAQEM---IGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKA 581
K+ Q+ + AL+E ++ IE+ + AA ++ + T Q E++ L
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 582 QLENEKQKVAELYSIHNSGDK------------SDIQDLLESVRLDKE-KAETLASSLQE 628
L+N++Q V+ L D+ +D +D E+ +KE KA +LA +L+E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 629 DLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKE 688
L ++ + + +A E+ +D+ + +L ET+ +MK
Sbjct: 1495 AL--------EAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1546
Query: 689 TIFELEDEVEQHRAVKL-------------HDNLIISDLENTVKK--LQDQKHDMEREIK 733
+ ELEDE++ KL +L D +N K+ LQ Q H+ E E++
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELE 1606
Query: 734 TLHRRLREESAEWRQFQADLQTAVVIANDI---KSEAQEEIGDLKRRLHEAQEKNEKLTK 790
++ +A ++ + DL+ + A+ + EA +++ L+ ++ + Q + E
Sbjct: 1607 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARA 1666
Query: 791 ELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSE 836
+EI + +E E+ ++E DL L++ + + R+ ++
Sbjct: 1667 SRDEIFATAKENEK-----KAKSLEADLMQLQEDLAAAERARKQAD 1707
Score = 98.2 bits (243), Expect = 4e-20
Identities = 162/757 (21%), Positives = 310/757 (40%), Gaps = 100/757 (13%)
Query: 124 ERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAALEA 183
+ + E T + K A N L K + + +K + +++ + LEA
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK---KKKLEA 1259
Query: 184 KVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTL 243
+V++L + K D E R EL D +L NE S +E E DV S
Sbjct: 1260 QVQELQS--KCSDGE--RARAELNDKVHKLQ-NEVESVTGMLNEAEGKAIKLAKDVASLS 1314
Query: 244 LQLQEQNTAIREELNQLKNEN---RMLKDRLNALGFSLEQRLDNSEKLFGYQS-LSPEIT 299
QLQ+ ++EE Q N + R L++ N+L L++ ++ + L + S L+ +++
Sbjct: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
Query: 300 PDNQS--DGGGTLTSSVEGSA--PGSVEDLLSQDENTLMDHQHSNSMDN-LDSECSEVYQ 354
+ D T+ + EG +E+L Q E + N L E ++
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 355 PLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEEL 414
L + + + + + + SS A E A R + E S + L
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR--EKETKALSLARAL 1492
Query: 415 QATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHH 474
+ L+ +L++ + L +E E L K + +++ + Q+E ++ L+E
Sbjct: 1493 EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE 1552
Query: 475 ISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMI 534
ED K + LE L +FER+ L+ ++ N+E +
Sbjct: 1553 DELQATEDAK----LRLEVNMQAL--KGQFERD------------LQARDEQNEEKRRQ- 1593
Query: 535 GALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIE--------------MNRLK 580
L+ + H E +E E+K +A AA ++ + + +++ + +L+
Sbjct: 1594 --LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 581 AQ-------LENEKQKVAELYSIHNSGDKS---------DIQDLLESVRLDKEKAETLAS 624
AQ LE+ + E+++ +K +Q+ L + +++A+
Sbjct: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
Query: 625 SLQEDLAHTRNDANRLQDA-------IAKVEDEYRAFQ----------EEAKKQIEDLNM 667
L E+LA + + N LQD IA++E+E Q +A +Q E L+
Sbjct: 1712 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSN 1771
Query: 668 TLEKLRSDLDEKETERSDMKETIFELEDEV-EQHRAVKLHDNLIISDLENTVKKLQDQKH 726
L RS + E+ R ++ EL ++ E AVK I+ LE + +L++Q
Sbjct: 1772 ELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE 1831
Query: 727 DMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQE---EIGDLKRRLHEAQE 783
RE + + L+++ + ++ ++ +A K +A++ + LKR+L EA+E
Sbjct: 1832 QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEE 1891
Query: 784 KNE-------KLTKELEEIKSRKQEEERGRVYNYMNA 813
+++ KL +EL+E + + E GR N + +
Sbjct: 1892 ESQRINANRRKLQRELDE--ATESNEAMGREVNALKS 1926
Score = 95.5 bits (236), Expect = 2e-19
Identities = 143/679 (21%), Positives = 284/679 (41%), Gaps = 97/679 (14%)
Query: 167 SKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKS 226
++ K+ D A+L ++++D L + + + L++ +LR + + +D + +E
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD-EEME 1357
Query: 227 EKETIMAHQPT-------------DVESTLLQLQEQNTAIREELNQLKN---ENRMLKDR 270
K+ + H T D ST+ L+E ++E+ L E D+
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417
Query: 271 LNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDE 330
L L+Q LD+ + DNQ L S++E + LL++++
Sbjct: 1418 LEKTKNRLQQELDDLV-----------VDLDNQRQ----LVSNLE-KKQRKFDQLLAEEK 1461
Query: 331 NTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASE 390
N + ++++ D ++E E S AL+ ++ E +ER+ K +
Sbjct: 1462 N--ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEE----LERTNKMLKAEMED 1515
Query: 391 V--SVACLTERIHQMEENQHSTS---EELQATLQELADLQQITQELNSENE-----RLGE 440
+ S + + +H++E+++ + EE++ L+EL D Q T++ E G+
Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQ 1575
Query: 441 EKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAE 500
+ L Q +K RQ+ + + L++ + K +LE DL
Sbjct: 1576 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK----KLEGDLKDLEL 1631
Query: 501 NARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAA 560
A + G ++ + K+ Q +E+ A R E+E+K K+ L A
Sbjct: 1632 QAD---SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS-LEA 1687
Query: 561 TLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAE 620
L + + +A+ + R + Q + EK+++AE + SG ++ +QD +K + E
Sbjct: 1688 DLMQLQEDLAAAE----RARKQADLEKEELAEELASSLSG-RNALQD-------EKRRLE 1735
Query: 621 TLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEE-------------AKKQIEDLNM 667
+ L+E+L + + + D + K + E A++Q+E N
Sbjct: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN- 1794
Query: 668 TLEKLRSDLDEKE-TERSDMKETIF-------ELEDEVEQHRAVKLHDNLIISDLENTVK 719
++LRS L E E +S K TI +LE++VEQ K + + +K
Sbjct: 1795 --KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
Query: 720 KLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLH 779
++ Q D + + + + +A +Q + L+ A + I + ++ L+R L
Sbjct: 1853 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK----LQRELD 1908
Query: 780 EAQEKNEKLTKELEEIKSR 798
EA E NE + +E+ +KS+
Sbjct: 1909 EATESNEAMGREVNALKSK 1927
Score = 84.0 bits (206), Expect = 7e-16
Identities = 98/475 (20%), Positives = 208/475 (43%), Gaps = 66/475 (13%)
Query: 399 RIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSD---K 455
++ + EE + +ELQ T + + +EL ++ +L EEK +L E L +++ +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 456 LEHFSRQIEYFRSLLDE--HHISYVIDEDVKSGRYMELE-----QRYMDLAENARFE--- 505
E ++ + L+E H + ++E+ G+ ++ E Q+ +DL E E
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 506 REQL--------LGVQQHLSNTLKMAEQDNKEAQEMIGALKER-SHHMERIIESEQKGK- 555
R++L +++ L M +Q+NK ++E L+ER S + E E+K K
Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKN 1024
Query: 556 --------AALAATLEEYKATVASDQIEMNRLKAQLENE----KQKVAELYSIHNSGDKS 603
++ + LE + E+ +LK +LE + +++A+L ++
Sbjct: 1025 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL--------QA 1076
Query: 604 DIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVE------DEYRAFQEE 657
I +L + +E+ + + L +++A N ++++ + D RA + +
Sbjct: 1077 QIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNK 1136
Query: 658 AKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENT 717
A+KQ DL LE L+++L++ + +E + E EV ++ L+
Sbjct: 1137 AEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----------TVLKKALDEE 1186
Query: 718 VKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRR 777
+ + Q +M ++ L E+ ++++ +A+L ++ E+ L +
Sbjct: 1187 TRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQA 1246
Query: 778 LHEAQEKNEKLTKELEEIKSRKQEEERGR------VYNYMNAVERDLAALRQGMG 826
E + K +KL +++E++S+ + ER R V+ N VE L + G
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1301
Score = 72.8 bits (177), Expect = 2e-12
Identities = 143/685 (20%), Positives = 280/685 (40%), Gaps = 103/685 (15%)
Query: 99 KISTGTASSTKRSTSTGNKESSSTRERLRERTRLNQSKKLPSAGQGANDMAL-AKRSRSR 157
K++ AS + + T TR++L T+L Q ++ ++ Q D + AK++ R
Sbjct: 1305 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1364
Query: 158 TATECDVRMSKSKSDNQ--ISDRAALEAKVKDLLTLAKTKDVEILHLRNE--------LR 207
+ ++++S SK Q S ALE K K++E L + E L
Sbjct: 1365 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRF-----QKEIENLTQQYEEKAAAYDKLE 1419
Query: 208 DMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIR--EELNQLKNENR 265
+ +L D D ++++ + + + L +E+N + + +E ++ + E R
Sbjct: 1420 KTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
Query: 266 MLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDL 325
+ + +L +LE+ L+ E+L +EDL
Sbjct: 1480 EKETKALSLARALEEALEAKEEL-----------------------ERTNKMLKAEMEDL 1516
Query: 326 LSQDENTLMD-HQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGS 384
+S ++ + H+ S L+++ E+ L +D L A ++ +++ + KG
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ-ALKGQ 1575
Query: 385 SGNASEVSVACLTERIHQMEENQHSTSEELQATLQELA-----------DLQQITQELNS 433
+ E+ Q++ H EL+ ++ A DL+ + EL +
Sbjct: 1576 FERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL--ELQA 1633
Query: 434 ENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELE- 492
++ G E+ I + L + +++ F R++E R+ DE I E+ K + +E +
Sbjct: 1634 DSAIKGREEAI--KQLRKLQAQMKDFQRELEDARASRDE--IFATAKENEKKAKSLEADL 1689
Query: 493 ---QRYMDLAENAR----FEREQLLGVQQHLSNTL--KMAEQDNKEAQEMIGA-----LK 538
Q + AE AR E+E+L + L+++L + A QD K E A L+
Sbjct: 1690 MQLQEDLAAAERARKQADLEKEELA---EELASSLSGRNALQDEKRRLEARIAQLEEELE 1746
Query: 539 ERSHHMERIIESEQKGKAA---LAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYS 595
E +ME + + +K L+ L ++T ++ +L+ Q + + K+ E+
Sbjct: 1747 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG 1806
Query: 596 IHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQ 655
S KS I L + +E+ E A Q + +L++ + +VEDE R
Sbjct: 1807 AVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDE-RKMA 1865
Query: 656 EEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLE 715
E+ K+Q E N +++L+ L+E E E + +L+ E+++
Sbjct: 1866 EQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE---------------- 1909
Query: 716 NTVKKLQDQKHDMEREIKTLHRRLR 740
+ M RE+ L +LR
Sbjct: 1910 -----ATESNEAMGREVNALKSKLR 1929
>gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 100 bits (248), Expect = 1e-20
Identities = 122/461 (26%), Positives = 201/461 (43%), Gaps = 58/461 (12%)
Query: 678 EKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHR 737
+ E + KE F +E+E R L + I +++ + Q D++ + K L +
Sbjct: 87 DPHAEEFEDKEWTFVIENESPSGRRKALATSSI--NMKQYASPMPTQT-DVKLKFKPLSK 143
Query: 738 RLREESAEWRQFQADLQTAVVIANDIKSEA------QEEIGDLKRRLHEAQEKNEKLTKE 791
++ + ++ L+ D++S A Q +IG+L + ++ +E +
Sbjct: 144 KVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQ 203
Query: 792 LEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSST--------SSEPTPTVKT 843
E K+ K E ++ N+++ E+DLA + ++ S EP +
Sbjct: 204 EE--KAAKITELINKL-NFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETAS 260
Query: 844 LIKSFDSA-SQVPNPAAAAIPRTPLSPSPMKTPPAAAV---SPMQ---RHSISGPISTSK 896
K+ DS + NP +TP +P P A SP Q R +I P+ SK
Sbjct: 261 PRKTEDSFYNNSYNPFKEV--QTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIR-PVDMSK 317
Query: 897 PLTALSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMES-AKTLSVSRRSSEEVKRDI 955
L A S K +E L ++ P S P + + + L RR VKR
Sbjct: 318 YLYADSSKTE-------EEELDESNPFYEPKSTPPPNNLVNPVQELETERR----VKRKA 366
Query: 956 SAQEGASPAS-LMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKR 1014
A SP + ++ T S LS+SP S P+ L R+ S+
Sbjct: 367 PAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSP-------------VLGRKPNASQ- 412
Query: 1015 NALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFML 1074
+LL WC++ T+ Y+ + ITNF++SW +GL+FCA+LH + P I Y+ LN QD + N
Sbjct: 413 -SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKK 471
Query: 1075 AFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYF 1115
A+ S+GI L+ ++MV PD VM Y+ I +F
Sbjct: 472 AYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 512
Score = 48.1 bits (113), Expect = 5e-05
Identities = 77/424 (18%), Positives = 174/424 (41%), Gaps = 24/424 (5%)
Query: 396 LTERIHQMEENQHSTSEELQATLQELADLQQITQE-LNSENERLGEEKVILMESLCQQSD 454
L ++ H S + + TL +I Q L S E L E +L+E ++
Sbjct: 739 LAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQ-ARRDA 797
Query: 455 KLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENAR--FEREQLLGV 512
L+ ++ + +S DE+ R +L +R L AR + +L
Sbjct: 798 ALKAGNKHNTNTATPFCNRQLSDQQDEE----RRRQLRERARQLIAEARSGVKMSELPSY 853
Query: 513 QQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASD 572
+ + LK + + E + LK + + + AA A E + + S
Sbjct: 854 GEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSG 913
Query: 573 QIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAH 632
++ + Q E+ + ++S ++ K+ +Q + + E S+QED
Sbjct: 914 TEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQ--RSIQEDTKK 971
Query: 633 TRNDANRLQDAIAKV-EDEY--RAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKET 689
+ + + K EDE + F++ ++ + +L LE + +D +
Sbjct: 972 GNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGEL-AALENEQKQIDTRAALVEKRLRY 1030
Query: 690 IFELEDEVEQHRAVKLHDNLIISDLENTVKKLQ-----DQKHDMEREIKTLHRRLREESA 744
+ + E+ A+ ++++ ++++ +++HD+ER + L+R LR A
Sbjct: 1031 LMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLA 1090
Query: 745 --EWRQFQADLQTAVVIANDIKSEAQEE---IGDLKRRLHEAQEKNEKLTKELEEIKSRK 799
+W++ +A + ++ +++ + + + DL + +A+E++E L + LE+ K +
Sbjct: 1091 IEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKM 1150
Query: 800 QEEE 803
++E
Sbjct: 1151 AKKE 1154
>gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 100 bits (248), Expect = 1e-20
Identities = 122/461 (26%), Positives = 201/461 (43%), Gaps = 58/461 (12%)
Query: 678 EKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHR 737
+ E + KE F +E+E R L + I +++ + Q D++ + K L +
Sbjct: 87 DPHAEEFEDKEWTFVIENESPSGRRKALATSSI--NMKQYASPMPTQT-DVKLKFKPLSK 143
Query: 738 RLREESAEWRQFQADLQTAVVIANDIKSEA------QEEIGDLKRRLHEAQEKNEKLTKE 791
++ + ++ L+ D++S A Q +IG+L + ++ +E +
Sbjct: 144 KVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQ 203
Query: 792 LEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSST--------SSEPTPTVKT 843
E K+ K E ++ N+++ E+DLA + ++ S EP +
Sbjct: 204 EE--KAAKITELINKL-NFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETAS 260
Query: 844 LIKSFDSA-SQVPNPAAAAIPRTPLSPSPMKTPPAAAV---SPMQ---RHSISGPISTSK 896
K+ DS + NP +TP +P P A SP Q R +I P+ SK
Sbjct: 261 PRKTEDSFYNNSYNPFKEV--QTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIR-PVDMSK 317
Query: 897 PLTALSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMES-AKTLSVSRRSSEEVKRDI 955
L A S K +E L ++ P S P + + + L RR VKR
Sbjct: 318 YLYADSSKTE-------EEELDESNPFYEPKSTPPPNNLVNPVQELETERR----VKRKA 366
Query: 956 SAQEGASPAS-LMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKR 1014
A SP + ++ T S LS+SP S P+ L R+ S+
Sbjct: 367 PAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSP-------------VLGRKPNASQ- 412
Query: 1015 NALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFML 1074
+LL WC++ T+ Y+ + ITNF++SW +GL+FCA+LH + P I Y+ LN QD + N
Sbjct: 413 -SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKK 471
Query: 1075 AFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYF 1115
A+ S+GI L+ ++MV PD VM Y+ I +F
Sbjct: 472 AYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 512
Score = 48.1 bits (113), Expect = 5e-05
Identities = 77/424 (18%), Positives = 174/424 (41%), Gaps = 24/424 (5%)
Query: 396 LTERIHQMEENQHSTSEELQATLQELADLQQITQE-LNSENERLGEEKVILMESLCQQSD 454
L ++ H S + + TL +I Q L S E L E +L+E ++
Sbjct: 739 LAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQ-ARRDA 797
Query: 455 KLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENAR--FEREQLLGV 512
L+ ++ + +S DE+ R +L +R L AR + +L
Sbjct: 798 ALKAGNKHNTNTATPFCNRQLSDQQDEE----RRRQLRERARQLIAEARSGVKMSELPSY 853
Query: 513 QQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASD 572
+ + LK + + E + LK + + + AA A E + + S
Sbjct: 854 GEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSG 913
Query: 573 QIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAH 632
++ + Q E+ + ++S ++ K+ +Q + + E S+QED
Sbjct: 914 TEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQ--RSIQEDTKK 971
Query: 633 TRNDANRLQDAIAKV-EDEY--RAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKET 689
+ + + K EDE + F++ ++ + +L LE + +D +
Sbjct: 972 GNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGEL-AALENEQKQIDTRAALVEKRLRY 1030
Query: 690 IFELEDEVEQHRAVKLHDNLIISDLENTVKKLQ-----DQKHDMEREIKTLHRRLREESA 744
+ + E+ A+ ++++ ++++ +++HD+ER + L+R LR A
Sbjct: 1031 LMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLA 1090
Query: 745 --EWRQFQADLQTAVVIANDIKSEAQEE---IGDLKRRLHEAQEKNEKLTKELEEIKSRK 799
+W++ +A + ++ +++ + + + DL + +A+E++E L + LE+ K +
Sbjct: 1091 IEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKM 1150
Query: 800 QEEE 803
++E
Sbjct: 1151 AKKE 1154
>gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]
Length = 1196
Score = 100 bits (248), Expect = 1e-20
Identities = 122/461 (26%), Positives = 201/461 (43%), Gaps = 58/461 (12%)
Query: 678 EKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHR 737
+ E + KE F +E+E R L + I +++ + Q D++ + K L +
Sbjct: 87 DPHAEEFEDKEWTFVIENESPSGRRKALATSSI--NMKQYASPMPTQT-DVKLKFKPLSK 143
Query: 738 RLREESAEWRQFQADLQTAVVIANDIKSEA------QEEIGDLKRRLHEAQEKNEKLTKE 791
++ + ++ L+ D++S A Q +IG+L + ++ +E +
Sbjct: 144 KVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQ 203
Query: 792 LEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSST--------SSEPTPTVKT 843
E K+ K E ++ N+++ E+DLA + ++ S EP +
Sbjct: 204 EE--KAAKITELINKL-NFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETAS 260
Query: 844 LIKSFDSA-SQVPNPAAAAIPRTPLSPSPMKTPPAAAV---SPMQ---RHSISGPISTSK 896
K+ DS + NP +TP +P P A SP Q R +I P+ SK
Sbjct: 261 PRKTEDSFYNNSYNPFKEV--QTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIR-PVDMSK 317
Query: 897 PLTALSDKRPNYGEIPVQEHLLRTSSASRPASLPRVPAMES-AKTLSVSRRSSEEVKRDI 955
L A S K +E L ++ P S P + + + L RR VKR
Sbjct: 318 YLYADSSKTE-------EEELDESNPFYEPKSTPPPNNLVNPVQELETERR----VKRKA 366
Query: 956 SAQEGASPAS-LMAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKR 1014
A SP + ++ T S LS+SP S P+ L R+ S+
Sbjct: 367 PAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSP-------------VLGRKPNASQ- 412
Query: 1015 NALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFML 1074
+LL WC++ T+ Y+ + ITNF++SW +GL+FCA+LH + P I Y+ LN QD + N
Sbjct: 413 -SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKK 471
Query: 1075 AFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYF 1115
A+ S+GI L+ ++MV PD VM Y+ I +F
Sbjct: 472 AYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 512
Score = 47.4 bits (111), Expect = 8e-05
Identities = 55/302 (18%), Positives = 131/302 (43%), Gaps = 21/302 (6%)
Query: 515 HLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQI 574
+L N L EQ++K + L E + + AA A E + + S
Sbjct: 897 NLENDLDTPEQNSKLVDLKLKKLLEVQPQV-----ANSPSSAAQKAVTESSEQDMKSGTE 951
Query: 575 EMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTR 634
++ + Q E+ + ++S ++ K+ +Q + + E S+QED
Sbjct: 952 DLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQ--RSIQEDTKKGN 1009
Query: 635 NDANRLQDAIAKV-EDEY--RAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIF 691
+ + + K EDE + F++ ++ + +L LE + +D + +
Sbjct: 1010 EEKAAITETQRKPSEDEVLNKGFKDTSQYVVGEL-AALENEQKQIDTRAALVEKRLRYLM 1068
Query: 692 ELEDEVEQHRAVKLHDNLIISDLENTVKKLQ-----DQKHDMEREIKTLHRRLREESA-- 744
+ E+ A+ ++++ ++++ +++HD+ER + L+R LR A
Sbjct: 1069 DTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIE 1128
Query: 745 EWRQFQADLQTAVVIANDIKSEAQEE---IGDLKRRLHEAQEKNEKLTKELEEIKSRKQE 801
+W++ +A + ++ +++ + + + DL + +A+E++E L + LE+ K + +
Sbjct: 1129 DWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAK 1188
Query: 802 EE 803
+E
Sbjct: 1189 KE 1190
>gi|19913394 smoothelin isoform c [Homo sapiens]
Length = 917
Score = 99.8 bits (247), Expect = 1e-20
Identities = 66/203 (32%), Positives = 108/203 (53%), Gaps = 24/203 (11%)
Query: 935 MESAKTLSVSRRSSEEVKRDISAQEGASP--ASLMAMGTTSPQ-----LSLSSSPTASVT 987
M KT S S SS+++ ++ ASP SL A+ + + S P S +
Sbjct: 703 MMQTKTFS-SSSSSKKMGSIFDREDQASPRAGSLAALEKRQAEKKKELMKAQSLPKTSAS 761
Query: 988 PTTRSRIREERKD--------PLSALAREYGGSKRNA------LLKWCQKKTEGYQNIDI 1033
++ I + K+ P +A+ R NA LL WC+ KT GY+++DI
Sbjct: 762 QARKAMIEKLEKEGAAGSPGGPRAAVQRSTSFGVPNANSIKQMLLDWCRAKTRGYEHVDI 821
Query: 1034 TNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAES-VGIKSTLDINE 1092
NFSSSW+DG+AFCAL+H + P Y +L+ Q++R+NF +AF +AE V +++++
Sbjct: 822 QNFSSSWSDGMAFCALVHNFFPEAFDYGQLSPQNRRQNFEVAFSSAEMLVDCVPLVEVDD 881
Query: 1093 -MVRTERPDWQNVMLYVTAIYKY 1114
M+ ++PD + V YV ++Y +
Sbjct: 882 MMIMGKKPDPKCVFTYVQSLYNH 904
Score = 32.7 bits (73), Expect = 2.0
Identities = 59/303 (19%), Positives = 107/303 (35%), Gaps = 44/303 (14%)
Query: 714 LENTVKKLQDQKHDMEREI---KTLHRRLREESAEW---RQFQADLQTAVV-IANDIKSE 766
+ + +++LQ Q+ + E E K ++ W +Q +A+ + A+ +A + E
Sbjct: 30 IRSAIRELQRQELEREEEALASKRFRAERQDNKENWLHSQQREAEQRAALARLAGQL--E 87
Query: 767 AQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMG 826
+ ++ +L L A E E+ + R QE E + + + + + G
Sbjct: 88 SMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQEIEAATLAGRLYSGRPNSGSREDSKG 147
Query: 827 LS---------------RRSSTSSEPTPTVK---------TLIKSFDSASQVPNPAAAAI 862
L+ + + S+PTPT + TL+ S +PA+ +
Sbjct: 148 LAAHRLEQCEVPEREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSS 207
Query: 863 PRTPLSPSPMKTPPAAAVSPMQRHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSS 922
TP SP P P A + P P S + +P E +
Sbjct: 208 SPTPASPEPPLEP--AEAQCLTAEVPGSPEPPPSPPKTTSPEPQESPTLPSTEGQVVNKL 265
Query: 923 ASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEGASPASLMAMGTTSPQLSLSSSP 982
S P P S +R S+ + D++ SL + P + S+P
Sbjct: 266 LSGPKETPAAQ--------SPTRGPSDTKRADVAGPRPCQ-RSLSVLSPRQPAQNRESTP 316
Query: 983 TAS 985
AS
Sbjct: 317 LAS 319
>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
Length = 1231
Score = 99.0 bits (245), Expect = 2e-20
Identities = 105/365 (28%), Positives = 157/365 (43%), Gaps = 48/365 (13%)
Query: 770 EIGDLKRRLHEAQEKNEKLTKE--LEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGL 827
EI + L E + K+ + KS EE N+++ E+DLA +
Sbjct: 212 EIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFD 271
Query: 828 SRRSST--------SSEPTPTVKTLIKSFDSA-SQVPNPAAAAIPRTPLSPSPMKTPPAA 878
++ S EP + K+ DS + NP +TP +P P A
Sbjct: 272 DPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEV--QTPQYLNPFDEPEAF 329
Query: 879 AV---SPMQ---RHSISGPISTSKPLTALSDKRPNYGEIPVQEHLLRTSSASRPASLPRV 932
SP Q R +I P+ SK L A S K +E L ++ P S P
Sbjct: 330 VTIKDSPPQSTKRKNIR-PVDMSKYLYADSSKTE-------EEELDESNPFYEPKSTPPP 381
Query: 933 PAMES-AKTLSVSRRSSEEVKRDISAQEGASPAS-LMAMGTTSPQLSLSSSPTASVTPTT 990
+ + + L RR VKR A SP + ++ T S LS+SP S P+
Sbjct: 382 NNLVNPVQELETERR----VKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSP 437
Query: 991 RSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALL 1050
L R+ S+ +LL WC++ T+ Y+ + ITNF++SW +GL+FCA+L
Sbjct: 438 -------------VLGRKPNASQ--SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAIL 482
Query: 1051 HTYLPAHIPYQELNSQDKRRNFMLAFQAAESVGIKSTLDINEMVRTERPDWQNVMLYVTA 1110
H + P I Y+ LN QD + N A+ S+GI L+ ++MV PD VM Y+
Sbjct: 483 HHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQ 542
Query: 1111 IYKYF 1115
I +F
Sbjct: 543 IRAHF 547
Score = 47.4 bits (111), Expect = 8e-05
Identities = 55/302 (18%), Positives = 131/302 (43%), Gaps = 21/302 (6%)
Query: 515 HLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQI 574
+L N L EQ++K + L E + + AA A E + + S
Sbjct: 932 NLENDLDTPEQNSKLVDLKLKKLLEVQPQV-----ANSPSSAAQKAVTESSEQDMKSGTE 986
Query: 575 EMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTR 634
++ + Q E+ + ++S ++ K+ +Q + + E S+QED
Sbjct: 987 DLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQ--RSIQEDTKKGN 1044
Query: 635 NDANRLQDAIAKV-EDEY--RAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIF 691
+ + + K EDE + F++ ++ + +L LE + +D + +
Sbjct: 1045 EEKAAITETQRKPSEDEVLNKGFKDTSQYVVGEL-AALENEQKQIDTRAALVEKRLRYLM 1103
Query: 692 ELEDEVEQHRAVKLHDNLIISDLENTVKKLQ-----DQKHDMEREIKTLHRRLREESA-- 744
+ E+ A+ ++++ ++++ +++HD+ER + L+R LR A
Sbjct: 1104 DTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIE 1163
Query: 745 EWRQFQADLQTAVVIANDIKSEAQEE---IGDLKRRLHEAQEKNEKLTKELEEIKSRKQE 801
+W++ +A + ++ +++ + + + DL + +A+E++E L + LE+ K + +
Sbjct: 1164 DWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAK 1223
Query: 802 EE 803
+E
Sbjct: 1224 KE 1225
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 96.7 bits (239), Expect = 1e-19
Identities = 158/694 (22%), Positives = 293/694 (42%), Gaps = 72/694 (10%)
Query: 165 RMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDM-RAQLGI-NEDHSEG 222
R SKS+S + R+ EA VK + T+ + DM R + + ++ EG
Sbjct: 1759 RSSKSQSSASLIWRSEAEASVKSCVHEEHTRVTDESIPSYSGSDMPRNDINMWSKVTEEG 1818
Query: 223 DEKSEKETIMAHQPTDV----ESTLLQLQEQNTAIREELNQLKNENRMLKDRLNA----- 273
E S++ T++ E +L + + A E+L + +E +
Sbjct: 1819 TELSQRLVRSGFAGTEIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTEL 1878
Query: 274 LGFSLEQRLDNSEKLFGYQSLSPEITPDNQS-DGGGTLTSSVEGSAPGSVEDLLSQDENT 332
+ S Q+ + +E L + L + ++++ + S EG G DE T
Sbjct: 1879 MRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYA------DEKT 1932
Query: 333 LMDHQHSNSMDNLDSECSEVYQPLTSSD--DALDAPSSSESEGIPSIERSRKGSSGNASE 390
L + Q D +D E+ L +S+ L+A E + R ++ A
Sbjct: 1933 LFERQIQEKTDIIDRLEQEL---LCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGP 1989
Query: 391 VSVACL--TERIHQMEENQHSTSEELQATLQELADLQQI-TQELNSENERLGEEKVILME 447
V L TE++ + + +E+++ LQ+ +I +E S L +EK +
Sbjct: 1990 VEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELM 2049
Query: 448 SLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQ------RYMDLAEN 501
L QQ+ LE +Q+E R LDE I + DV +LEQ R+ ++E+
Sbjct: 2050 DLRQQNQALE---KQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEH 2106
Query: 502 ARFEREQLLGVQQHLSN-------TLKMAEQDNKEAQEMIGALKERSHHMER--IIES-- 550
E EQL + ++ + + ++D +E E I L+ R +E+ ++E
Sbjct: 2107 QTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRK 2166
Query: 551 -----EQKGKAALAATLEEYKATVASDQIEMNRLKAQLE-------NEKQKVAELY---S 595
E K + +L L+ + + + E+ L+ QLE N+ ++V +L+
Sbjct: 2167 HFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLE 2226
Query: 596 IHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQ 655
I + +Q+L + +L K+ E L +++E A + D + L A++ E
Sbjct: 2227 IQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEI 2286
Query: 656 EEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVE----QHRAVKLHDNLII 711
++ +Q+ L ++L+ D K E + E I +LE ++E VK + I
Sbjct: 2287 DQLNEQVTKLQ---QQLKITTDNKVIEEKN--ELIRDLETQIECLMSDQECVKRNREEEI 2341
Query: 712 SDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSE-AQEE 770
L ++KLQ + ++ ++ L EE A+ + Q D+ A +A + + E A EE
Sbjct: 2342 EQLNEVIEKLQQELANIGQKTSMNAHSLSEE-ADSLKHQLDVVIAEKLALEQQVETANEE 2400
Query: 771 IGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEER 804
+ +K L E K +LT+EL +K ++ E+
Sbjct: 2401 MTFMKNVLKETNFKMNQLTQELFSLKRERESVEK 2434
Score = 82.8 bits (203), Expect = 2e-15
Identities = 163/812 (20%), Positives = 325/812 (40%), Gaps = 159/812 (19%)
Query: 103 GTASSTKRSTSTGNKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATEC 162
G + + +E T E T +Q ++ A++ R+ + ++T
Sbjct: 205 GIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETL---RNSTHSSTAA 261
Query: 163 DVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKD---VEILHLRNELRDMRAQLGINEDH 219
D+ +K + ++ + LE + L K K+ ++I L+ +++ + ++
Sbjct: 262 DLLQAKQQI---LTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVEN 318
Query: 220 SEGDEKSEKETIMAHQPTDV---ESTLLQLQEQNTAIREELNQLKNE----NRMLKDRLN 272
S +E EKETI+ T + E L+L+++ T + L +L+ + N+ +K+
Sbjct: 319 SNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKL 378
Query: 273 ALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENT 332
L S ++ +SE++ E+ N D SQ E
Sbjct: 379 ELTNSKQKERQSSEEIKQLMGTVEELQKRNHKD---------------------SQFETD 417
Query: 333 L---MDHQHSNSMDNLDSECSEVY-QPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNA 388
+ M+ + ++ L +E E+Y Q + L ++ E ++ KG NA
Sbjct: 418 IVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQME---EMKTRHKGEMENA 474
Query: 389 SEVSVACLTERIHQMEENQHSTSEELQATLQELA--DLQQITQELNSENERLGEEKVILM 446
+ + T E Q L +A +L Q+ NS+ E+L EE +++
Sbjct: 475 --------------LRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLIL 520
Query: 447 ESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFER 506
E C +LE ++ + R E ++ R EQ E+ E
Sbjct: 521 EEKCALQRQLEDLVEELSFSR-------------EQIQRARQTIAEQ------ESKLNEA 561
Query: 507 EQLLGVQQHLSNTLKMAEQDNKEAQ--------------EMIGALKERSHHMERIIESEQ 552
+ L + L + A + KE + EM+ KE++ ++R+ ES++
Sbjct: 562 HKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLE--KEKNAVLDRMAESQE 619
Query: 553 KGKAALAATLEEYKATVA-SDQIEMNRLKAQLENEK----QKVAELYSIHN----SGDKS 603
A LE + + S + E+++LK LE E +K+ + IH G ++
Sbjct: 620 -------AELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQN 672
Query: 604 DIQDLLESVRLDKEKAETLAS----------SLQEDLAHTRNDANRLQDAIAKVEDEYRA 653
++ +E+++ +K+ T + LQ+ L +++++ LQ I +++ E
Sbjct: 673 EMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ--INELQKEIEI 730
Query: 654 FQEEAK------KQIEDLNMTLEKLRSDLDEK-----------ETERSDMKETIFELEDE 696
++E K +++++L + E L + EK E E S +K+ LED
Sbjct: 731 LRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDM 790
Query: 697 VEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTA 756
++ H V + LI L++ K +D + E EI L EE+ + +Q L
Sbjct: 791 LKIHTPVSQEERLIF--LDSIKSKSKDSVWEKEIEI------LIEENEDLKQQCIQLNEE 842
Query: 757 VVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMNAVER 816
+ + S A++ + L E K+ +LE+ K++++ E + +
Sbjct: 843 IEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSK---------- 892
Query: 817 DLAALRQGMGLSRRSSTSSEPTPTVKTLIKSF 848
L AL + + L R + T+ + +V K+F
Sbjct: 893 -LKALNEELHLQRINPTTVKMKSSVFDEDKTF 923
Score = 62.4 bits (150), Expect = 2e-09
Identities = 97/437 (22%), Positives = 187/437 (42%), Gaps = 69/437 (15%)
Query: 395 CLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSD 454
CL +RI + + E LQ AD + + E+ + + ++ K+ L Q+S+
Sbjct: 3055 CLEQRIQEQGVEYQAAMECLQK-----ADRRSLLSEIQALHAQMNGRKITLKRE--QESE 3107
Query: 455 KLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQ 514
K + + Y I + K + +E++ + + A +EQL
Sbjct: 3108 KPS--------------QELLEYNIQQ--KQSQMLEMQVELSSMKDRATELQEQLS---- 3147
Query: 515 HLSNTLKMAEQDNKEAQ---EMIGALKERSHHMERI--IESEQKGKAALAATLEEYKATV 569
S + +AE ++ AQ E+ LK + H++ + E K K L + T+
Sbjct: 3148 --SEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLND---TL 3202
Query: 570 ASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQED 629
AS+Q + L+ LE EK K+ DK +++DL S+ K++ L L++
Sbjct: 3203 ASEQKKSRELQWALEKEKAKLGR----SEERDKEELEDLKFSLESQKQRNLQLNLLLEQQ 3258
Query: 630 LAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKET 689
L ++ K+E + + + ++ + N+ L+ L E+E+ ++E
Sbjct: 3259 -------KQLLNESQQKIESQRMLYDAQLSEE-QGRNLELQVLL------ESEKVRIREM 3304
Query: 690 IFELEDEVEQHRAVKLHDN-------LIISDLENTVKKLQDQKHDMEREIKTLHRRLREE 742
L+ E E H ++ D L DL ++K ++KH E+ + + +
Sbjct: 3305 SSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLD 3364
Query: 743 SAEWRQ-FQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSR--K 799
S + RQ + D Q V +++E QE + ++++HE Q K E L ++LEE + + K
Sbjct: 3365 SLQTRQQMEKDRQ---VHRKTLQTE-QEANTEGQKKMHELQSKVEDLQRQLEEKRQQVYK 3420
Query: 800 QEEERGRVYNYMNAVER 816
+ E R+ M ++
Sbjct: 3421 LDLEGQRLQGIMQEFQK 3437
Score = 60.1 bits (144), Expect = 1e-08
Identities = 143/737 (19%), Positives = 293/737 (39%), Gaps = 93/737 (12%)
Query: 150 LAKRSRSRTATECDVRMSKSKSDNQISDR----AALEAKVKDL---LTLAKTKDVEILHL 202
LA + +T ++ +SK + I +R LE +V++L L + K +
Sbjct: 2114 LANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEA 2173
Query: 203 RNELRDMRAQLGINEDHSEGDEKS---------EKETIMAHQPTDVESTLLQLQEQNTAI 253
+ EL + QL D + EK + + ++ +V+ +QL+ Q
Sbjct: 2174 KPEL-SLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKES 2232
Query: 254 REELNQLKNENRMLKDRLNALGFSLEQ----RLDNSEKLFG-----YQSLSPEITPDN-- 302
L +L+ EN++ KD + LG ++++ + LFG Q EI N
Sbjct: 2233 TTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQ 2292
Query: 303 ----QSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQ-----HSNSMDNLDSECSEVY 353
Q T + V + DL +Q E + D + ++ L+ ++
Sbjct: 2293 VTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQ 2352
Query: 354 QPLTSSDDALDAPSSSESEGIPSIERSRKG--SSGNASEVSVACLTERIHQMEENQHSTS 411
Q L + + S SE S++ + A E V E + M+ T+
Sbjct: 2353 QELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETN 2412
Query: 412 EELQATLQELADLQQITQEL--------NSEN---ERLGEEK----VILMESLCQQSDKL 456
++ QEL L++ + + NS N + L ++K V+L E + +
Sbjct: 2413 FKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQ 2472
Query: 457 EHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRY---MDLAENARFEREQLLGVQ 513
+F E + + + E S + +EL Q Y D+ E +FE E L Q
Sbjct: 2473 TYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEML---Q 2529
Query: 514 QHLSNTLKMAEQDNKEA---QEMIGALKERSHHME--RIIESEQKG---KAALAATLEEY 565
+ + N K+ E+ A Q + A++E + + + I SE + + +E
Sbjct: 2530 KKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDEL 2589
Query: 566 KATVASDQIEMNRLKAQ---------LENEKQKVAELYSIHNSGDKSDIQDLLESVRLDK 616
+ +++ + ++ L++Q LE E+ ++AE + ++Q LLE +
Sbjct: 2590 GSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQ 2649
Query: 617 EKAETLASSLQEDLAHTRNDA--NRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRS 674
+ E S ++ T + + + + RA K ++ EKL+
Sbjct: 2650 REKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQE 2709
Query: 675 DLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIK- 733
+L KET + +++ + ++ D + + + + L I + E+ + + +K M +
Sbjct: 2710 ELLVKETNMTSLQKDLSQVRDHLAEAK-----EKLSILEKEDETEVQESKKACMFEPLPI 2764
Query: 734 TLHRRLREESAEWRQFQADLQTAVVIAN------DIKSE-AQEEIGDLKRRLHEAQEKNE 786
L + + ++ + + QT ++ +++SE + EE+ ++ + E EK +
Sbjct: 2765 KLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQ 2824
Query: 787 KL-TKELEEIKSRKQEE 802
+L E+ +++SR E
Sbjct: 2825 ELHAAEILDMESRHISE 2841
Score = 54.3 bits (129), Expect = 6e-07
Identities = 113/570 (19%), Positives = 236/570 (41%), Gaps = 97/570 (17%)
Query: 330 ENTLMDHQHSNSMDN--------LDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSR 381
E+T+M HS + + L+SE S T++DD SSE G + R+
Sbjct: 80 ESTIMRTLHSGEITSHEQGFSVELESEIS------TTADDC-----SSEVNGCSFVMRTG 128
Query: 382 KGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEE 441
K ++ E E+ + L+ ELA Q +ELN E L E
Sbjct: 129 KPTNLLREEE----FGVDDSYSEQGAQDSPTHLEMMESELAGKQHEIEELNRE---LEEM 181
Query: 442 KVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAEN 501
+V QQ + E +Q + + L + ++D ++EL ++ ++
Sbjct: 182 RVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQ----SQK 237
Query: 502 ARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAAT 561
+ + +QL + ++T D +A++ I +++ + ++E QK K
Sbjct: 238 LQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQ 297
Query: 562 LEEYKATVASDQIEMNRLKAQLEN-EKQKVAELYSIHNSGDKSDIQDLLESVRLDKEK-- 618
+ + + ++E ++ ++EN K+++ E +I + I++ +++ L K+K
Sbjct: 298 ISFLQEKIKVYEMEQDK---KVENSNKEEIQEKETIIEELNTKIIEEEKKTLEL-KDKLT 353
Query: 619 -AETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQI--------------- 662
A+ L LQE + + ++ + + + R EE K+ +
Sbjct: 354 TADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQ 413
Query: 663 ----------EDLNMTLEKLRSDLDEK------ETERSDMKETIFELEDEVEQHR----- 701
++ LE+LR++LDE + ++ +++ + ++E+ +H+
Sbjct: 414 FETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMEN 473
Query: 702 AVKLHDNLIISDLENTVK-----------KLQDQKHDMEREIKTLHRRLREESAEWRQFQ 750
A++ + N+ ++ E+ +K KLQD E+ + L L E+ A RQ +
Sbjct: 474 ALRSYSNITVN--EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLE 531
Query: 751 ADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEI----KSRKQEE--ER 804
DL + + + A++ I + + +L+EA + + EI +SRK+ E
Sbjct: 532 -DLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHE 590
Query: 805 GRVYNY---MNAVERDLAALRQGMGLSRRS 831
V NY + +E++ A+ M S+ +
Sbjct: 591 AEVTNYKIKLEMLEKEKNAVLDRMAESQEA 620
Score = 53.5 bits (127), Expect = 1e-06
Identities = 137/653 (20%), Positives = 246/653 (37%), Gaps = 121/653 (18%)
Query: 177 DRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQP 236
++ LE +V++L + + ++ N+L++ AQL + ++K+ ++ + H P
Sbjct: 737 EKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTP 796
Query: 237 TDVESTLLQL-----QEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDN---SEKL 288
E L+ L + +++ +E+ L EN LK + L +E++ + +EK
Sbjct: 797 VSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKN 856
Query: 289 F--GYQSLSPEI-----TPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNS 341
F YQ L E D+ D + E+L Q N S+
Sbjct: 857 FEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSV 916
Query: 342 MDNLDSECSE-------VYQPLTSSDDALDAPSSSE---SEGIPSIERSRKGSSGNAS-- 389
D + +E V + T + L+ + S+ + + K G S
Sbjct: 917 FDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFL 976
Query: 390 ------------EVSVACLTERI---HQMEENQHSTSEELQATLQELADLQQITQE--LN 432
+VS+ C I H EN S ++ + L + + E ++
Sbjct: 977 NEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVS 1036
Query: 433 SENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELE 492
N+ GEE I++E E+ + E + L H+ V E
Sbjct: 1037 KVNKSFGEESKIMVE----DKVSFENMTVGEESKQEQLILDHLPSVTKES---------S 1083
Query: 493 QRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQ 552
R +EN + ++E L V + N L++ EAQ + +L S H++++ E +
Sbjct: 1084 LRATQPSENDKLQKE--LNVLKSEQNDLRL----QMEAQRICLSL-VYSTHVDQVREYME 1136
Query: 553 KGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESV 612
K +L+E ++I+ + QLE + K E +GD+ LL
Sbjct: 1137 NEKDKALCSLKEELIFAQEEKIKELQKIHQLELQTMKTQE------TGDEGKPLHLLIG- 1189
Query: 613 RLDKEKAETLASSLQ--------------------EDLAH-----TRNDANRLQDAIAKV 647
+L K +E + LQ ED + + N+ LQD +V
Sbjct: 1190 KLQKAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKENSGDYISENEDPELQDYRYEV 1249
Query: 648 EDEYRAFQEEAKKQIEDLN-------------------MTLEKLRSDLDEKETERSDMKE 688
+D K E+ N M LE +L ++ETE +
Sbjct: 1250 QDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHS 1309
Query: 689 TIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLRE 741
+ LED H++ KL + DLE T KL++Q ++E I +L ++L+E
Sbjct: 1310 QMTNLEDIDVNHKS-KLSS---LQDLEKT--KLEEQVQELESLISSLQQQLKE 1356
Score = 49.3 bits (116), Expect = 2e-05
Identities = 148/792 (18%), Positives = 310/792 (39%), Gaps = 111/792 (14%)
Query: 116 NKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQI 175
NK + + L +TRL++ GQ + M L + E + S+ N
Sbjct: 1261 NKVTEEYNKLLVLQTRLSKIW-----GQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLE 1315
Query: 176 SDRAALEAKVKDLLTLAKTK-DVEILHLRNELRDMRAQLGINEDHSEGD--------EKS 226
++K+ L L KTK + ++ L + + ++ QL E + E + +
Sbjct: 1316 DIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKRLQAV 1375
Query: 227 EKETIMAHQPTD----VESTLLQLQEQNTAIREELN---QLKNENRMLKDRLNALGFSLE 279
+ T+ P D ES + + +++ ++ + E + K+ N + +
Sbjct: 1376 SESTVPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIEFSGEFGV-KEETNIVKLLEK 1434
Query: 280 QRLDNSEKLFGYQSLSPEITPDNQSD------GGGTLTSSVEGSAPGSVEDLLSQDENTL 333
Q + E+ +S I Q++ G SS + A E +
Sbjct: 1435 QYQEQLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFNEMKLS 1494
Query: 334 MDHQHSNSMDNLDSECSEVYQPLT------------SSDDALDAPSSSE-----SEGIPS 376
D + + +D + E ++PL+ S+ D D P S + SE + S
Sbjct: 1495 QDQIGFQTFETVDVKFKEEFKPLSKELGEHGKEILLSNSDPHDIPESKDCVLTISEEMFS 1554
Query: 377 IERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENE 436
+++ E+SV+ + + Q+ N+ + Q +++ + QQ T+ L +
Sbjct: 1555 KDKTFIVRQSIHDEISVSSM-DASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHM 1613
Query: 437 RLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISY---VIDEDVKSGRYMELEQ 493
R E + E Q ++++ +RQ+ S+ +E+ +S V+ E++++ + + L
Sbjct: 1614 RQMERQ---REDQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAG 1670
Query: 494 RYMDLAENARFEREQLLGVQQH---LSNTLKMAEQDNKEAQ---EMIG----ALKERSHH 543
R E + G + T K E D K E++ AL++ ++
Sbjct: 1671 REKLCCELRNSSTQTQNGNENQGEVEEQTFKEKELDRKPEDVPPEILSNERYALQKANNR 1730
Query: 544 MERIIESEQKGKAALAATLEEY---------KATVASDQIEMNRLKAQLEN----EKQKV 590
+ +I+ K AA+ T+ + K+ ++ I + +A +++ E +V
Sbjct: 1731 LLKILLEVVKTTAAVEETIGRHVLGILDRSSKSQSSASLIWRSEAEASVKSCVHEEHTRV 1790
Query: 591 AELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRND----------ANRL 640
+ SG D+ ++ +E E ++ A T D ++RL
Sbjct: 1791 TDESIPSYSGSDMPRNDINMWSKVTEEGTELSQRLVRSGFAGTEIDPENEELMLNISSRL 1850
Query: 641 QDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQH 700
Q A+ K+ + E Q+E +T +L + ++ E ++ + EL + + +
Sbjct: 1851 QAAVEKLLEAI----SETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEE 1906
Query: 701 RAVKLHDNLIISDLENTVKKLQDQKHDMEREIKT--------------LHRRLREESAEW 746
+ + +S E + D+K ER+I+ RL+E AE
Sbjct: 1907 SRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQ 1966
Query: 747 RQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGR 806
+Q Q + + + + K + E G ++++L ++ EKL KE E++ + E+ R
Sbjct: 1967 QQIQEERE----LLSRQKEAMKAEAGPVEQQL---LQETEKLMKEKLEVQC-QAEKVRDD 2018
Query: 807 VYNYMNAVERDL 818
+ + A+E D+
Sbjct: 2019 LQKQVKALEIDV 2030
Score = 46.2 bits (108), Expect = 2e-04
Identities = 119/659 (18%), Positives = 257/659 (38%), Gaps = 102/659 (15%)
Query: 175 ISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAH 234
+ ++ AL+ +++DL+ +I R + + ++L NE H + + +
Sbjct: 520 LEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKL--NEAHKSLSTVEDLKAEIVS 577
Query: 235 QPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSL 294
+ L+ + + T + +L L+ E + DR+ + +RL ++ LF ++
Sbjct: 578 ASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERL-RTQLLFSHEEE 636
Query: 295 SPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQ 354
++ D +E ++E L ++ L H + +D L +E S+ +
Sbjct: 637 LSKLKED------------LEIEHRINIEKL----KDNLGIH-YKQQIDGLQNEMSQKIE 679
Query: 355 PLTSSDDALDAPSSS---ESEGIPSIERSRKGSSGNASEVSVACLTERIH--QMEENQHS 409
+ D L + E + +++S S + + L + I + EE +
Sbjct: 680 TMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKG 739
Query: 410 TSE----ELQATLQELA--------DLQQITQELNSENERLGEEKVILMESL-----CQQ 452
T E ELQ + L DLQ+ +L +EN L +EK L + L Q
Sbjct: 740 TLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQ 799
Query: 453 SDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGV 512
++L + + E I +I+E+ +L+Q+ + L E +R
Sbjct: 800 EERLIFLDSIKSKSKDSVWEKEIEILIEENE------DLKQQCIQLNEEIEKQR------ 847
Query: 513 QQHLSNTLKMAEQD----NKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKAT 568
NT AE++ +E QE L + +E +S+ K + + L+
Sbjct: 848 -----NTFSFAEKNFEVNYQELQEEYACLLKVKDDLE---DSKNKQELEYKSKLKALNEE 899
Query: 569 VASDQIEMNRLKAQ---LENEKQKVAELYSIHN--SGDKSDIQDLLESVRLDKEKAETLA 623
+ +I +K + + +K VAE + D +++ + LE + +K +
Sbjct: 900 LHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRL 959
Query: 624 SSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSD-LDEKETE 682
S L E L + + L + + ++ E +E+ + +L + + R++ + +T+
Sbjct: 960 SDLSEQLKQKHGEISFLNEEVKSLKQE----KEQVSLRCRELEIIINHNRAENVQSCDTQ 1015
Query: 683 RSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREE 742
S + + + + + K++ + ++ K +E ++ + + EE
Sbjct: 1016 VSSLLDGVVTMTSRGAEGSVSKVNKSFG-----------EESKIMVEDKVSFENMTVGEE 1064
Query: 743 SAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQE 801
S + Q D +V + +++ E N+KL KEL +KS + +
Sbjct: 1065 SKQ-EQLILDHLPSVTKESSLRATQPSE--------------NDKLQKELNVLKSEQND 1108
>gi|169234649 smoothelin-like 2 isoform 2 [Homo sapiens]
Length = 317
Score = 96.7 bits (239), Expect = 1e-19
Identities = 74/269 (27%), Positives = 130/269 (48%), Gaps = 50/269 (18%)
Query: 855 PNPAAAAIPRTPLSPSPMKTP-----PAAAVSPM--QRHSISGPISTSKPLTALSDKRPN 907
P+P+ P TP SPS + P++ + +HS S P+ T P + +S + P
Sbjct: 85 PSPSEVITPWTP-SPSEKNSSFTWSVPSSGYGAVTASKHSNSPPLVTP-PQSPVSPQPPA 142
Query: 908 YGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEGASPASLM 967
++ Q R R +LPR ++ K L E+ +++ +A +G A
Sbjct: 143 ITQVHRQGE--RRRELVRSQTLPRTSEAQARKALF------EKWEQETAAGKGKGEA--- 191
Query: 968 AMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEG 1027
R+R++ + +++ + S + LL+WC+ KT G
Sbjct: 192 -----------------------RARLKRSQSFGVASAS-----SIKQILLEWCRSKTLG 223
Query: 1028 YQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAESV-GIKS 1086
YQ++D+ NFSSSW+DG+AFCAL+H++ P Y L+ +++NF LAF AE++ +
Sbjct: 224 YQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPTQRQKNFELAFTMAENLANCER 283
Query: 1087 TLDINE-MVRTERPDWQNVMLYVTAIYKY 1114
+++ + MV +PD V YV ++Y +
Sbjct: 284 LIEVEDMMVMGRKPDPMCVFTYVQSLYNH 312
>gi|169234647 smoothelin-like 2 isoform 1 [Homo sapiens]
Length = 461
Score = 96.7 bits (239), Expect = 1e-19
Identities = 74/269 (27%), Positives = 130/269 (48%), Gaps = 50/269 (18%)
Query: 855 PNPAAAAIPRTPLSPSPMKTP-----PAAAVSPM--QRHSISGPISTSKPLTALSDKRPN 907
P+P+ P TP SPS + P++ + +HS S P+ T P + +S + P
Sbjct: 229 PSPSEVITPWTP-SPSEKNSSFTWSVPSSGYGAVTASKHSNSPPLVTP-PQSPVSPQPPA 286
Query: 908 YGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEGASPASLM 967
++ Q R R +LPR ++ K L E+ +++ +A +G A
Sbjct: 287 ITQVHRQGE--RRRELVRSQTLPRTSEAQARKALF------EKWEQETAAGKGKGEA--- 335
Query: 968 AMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSALAREYGGSKRNALLKWCQKKTEG 1027
R+R++ + +++ + S + LL+WC+ KT G
Sbjct: 336 -----------------------RARLKRSQSFGVASAS-----SIKQILLEWCRSKTLG 367
Query: 1028 YQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAAESV-GIKS 1086
YQ++D+ NFSSSW+DG+AFCAL+H++ P Y L+ +++NF LAF AE++ +
Sbjct: 368 YQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYNSLSPTQRQKNFELAFTMAENLANCER 427
Query: 1087 TLDINE-MVRTERPDWQNVMLYVTAIYKY 1114
+++ + MV +PD V YV ++Y +
Sbjct: 428 LIEVEDMMVMGRKPDPMCVFTYVQSLYNH 456
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 95.9 bits (237), Expect = 2e-19
Identities = 209/1083 (19%), Positives = 409/1083 (37%), Gaps = 179/1083 (16%)
Query: 93 TVENKSKISTGTASSTKRSTSTGNKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAK 152
TV SK+ TG S +R + K+ S E L + R +L + D++L K
Sbjct: 1129 TVLENSKL-TGKISELERMVAELKKQKSRVEEEL-PKVREAAENELRKQQRNVEDISLQK 1186
Query: 153 RSRSRTATECDVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVE--ILHLRNELRDMR 210
A + + + + ++R + + AK VE +L+ RN+L +
Sbjct: 1187 IRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENT 1246
Query: 211 AQLGINEDH------SEGDEKSEKETIMAH--QPTDVESTLLQL---QEQNTAIREEL-- 257
EDH S D + +K +M + D E LL+L E++ A ++++
Sbjct: 1247 FTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAE 1306
Query: 258 NQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGS 317
QLK + ++ LE R +E + + + + P Q+ +T +
Sbjct: 1307 KQLKEKQKI----------ELEARRKITEIQYTCRENALPVCPITQATSCRAVTGLQQEH 1356
Query: 318 APGSVEDLLSQ-DENTLMDHQHSNSMDNLDSECSEVYQPLTSSD-------DALDAPSSS 369
E+L Q DE T + + M L E + + TSS+ D LD +++
Sbjct: 1357 DKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNT 1416
Query: 370 ESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQ 429
+ER + G ++++ ++ + T+ + + +QE +DL++I +
Sbjct: 1417 LRCLKLELERKDQAEKG---------YSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKR 1467
Query: 430 ELNSENERLGEEKVILMESLCQ-------QSDKLEHFSRQIEYFRSLLDEHHISYVIDED 482
E E L EK L + + ++H + QI FR D
Sbjct: 1468 NYQLELESLNHEKGKLQREVDRITRAHAVAEKNIQHLNSQIHSFR--------------D 1513
Query: 483 VKSGRYMELEQRYMD-LAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERS 541
K +++ QR D L E EQLL Q++ AE++N + + + E+S
Sbjct: 1514 EKELERLQICQRKSDHLKEQFEKSHEQLL---QNIK-----AEKENNDKIQRLNEELEKS 1565
Query: 542 HHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLEN---EKQKV---AELYS 595
+ +++ + +EE ++ M R++A+ EN EKQ + E
Sbjct: 1566 NECAEMLKQK----------VEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALK 1615
Query: 596 IHNSGDKSDIQDLLESVRLDKEKAETLASS---LQEDLAHTRNDANRLQDAIAKVEDEYR 652
I G K ++ E + + + L+EDLA ++N + + D+
Sbjct: 1616 IQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKC----DQQN 1671
Query: 653 AFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIIS 712
+ KK++ +LN L + ++E R + K + + + +
Sbjct: 1672 IIIQNTKKEVRNLNAEL-----NASKEEKRRGEQKVQLQQAQ----------------VQ 1710
Query: 713 DLENTVKKLQDQKHDMEREIKTLHRRL---REESAEWRQFQAD--------LQTAVVIAN 761
+L N +KK+QD+ H E + HR++ +EES +++Q + +++ V+ N
Sbjct: 1711 ELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITEN 1770
Query: 762 DIKS------EAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGRVYNYMN--- 812
DI Q+E + + ++L ++L++ + + Q+ + +Y
Sbjct: 1771 DISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQQYREQMQQGQHMEANHYQKCQK 1830
Query: 813 ------AVERDLAALRQGMGLS---------------RRSSTSSEPT--PTVKTLIKSFD 849
A +R++ L+Q M ++ ST+ + T P + +K
Sbjct: 1831 LEDELIAQKREVENLKQKMDQQIKEHEHQLVLLQCEIQKKSTAKDCTFKPDFEMTVKECQ 1890
Query: 850 SASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQRHSISGPISTS---KPLTALSDKRP 906
+ ++ + + TP SP T + +H + I +P A +K
Sbjct: 1891 HSGELSSRNTGHLHPTPRSPLLRWTQEPQPLEEKWQHRVVEQIPKEVQFQPPGAPLEKEK 1950
Query: 907 NYGEIPVQEHLLRTSSASRPASLPRVPAMESAKTLSVSRRSSEEVKRDISAQEGASPASL 966
+ + E+ +TS+ + P ++ + ++ + + Q+ A L
Sbjct: 1951 S--QQCYSEYFSQTSTELQITFDETNPITRLSEIEKIRDQALNNSRPPVRYQDNACEMEL 2008
Query: 967 MAMGTTSPQLSLSSSPTASVTPTTRSRIREERKDPLSAL-------AREYGGSKRNALLK 1019
+ + T L + T ++ K+P+ + R GG K+ LK
Sbjct: 2009 VKVLT-----PLEIAKNKQYDMHTEVTTLKQEKNPVPSAEEWMLEGCRASGGLKKGDFLK 2063
Query: 1020 WCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRNFMLAFQAA 1079
+ E +QN D + S +D F L HT + +L L +
Sbjct: 2064 -KGLEPETFQNFDGDHACSVRDDEFKFQGLRHTVTARQLVEAKLLDMRTIEQLRLGLKTV 2122
Query: 1080 ESV 1082
E V
Sbjct: 2123 EEV 2125
Score = 67.0 bits (162), Expect = 9e-11
Identities = 109/514 (21%), Positives = 220/514 (42%), Gaps = 67/514 (13%)
Query: 315 EGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGI 374
E S G+ DLL + + T++++ L + SE+ + + L S E +
Sbjct: 1112 ETSEHGAYSDLLQRQKATVLENS------KLTGKISELERMVAE----LKKQKSRVEEEL 1161
Query: 375 PSI----ERSRKGSSGNASEVSVACLT--ERIHQMEENQHSTSEELQATLQELADLQQIT 428
P + E + N ++S+ + Q + E +A +EL ++Q+T
Sbjct: 1162 PKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLT 1221
Query: 429 QELNSENERLGEEKVILMESLCQQSDKLEHFSRQIE---YFRSLLDEHHISYVIDEDVKS 485
E +E +R E+ +L +F Q+E + R L++H + +D+
Sbjct: 1222 IE--AEAKRAAVEENLL------------NFRNQLEENTFTRRTLEDH----LKRKDLSL 1263
Query: 486 GRYMELEQRYMDLAENARFEREQLLGVQQHLSNTL----KMAEQDNKEAQEMIGALKERS 541
+ + + M+ R E+LL + + + L ++AE+ KE Q++ L+ R
Sbjct: 1264 NDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKI--ELEARR 1321
Query: 542 HHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGD 601
E I+ + A + + + A ++ K + E KQ+V EL + + +
Sbjct: 1322 KITE--IQYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAE 1379
Query: 602 KSDIQDL---LESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEA 658
+ D+++L L +++L+K +E A L++ L T N L+ + + + + + ++
Sbjct: 1380 Q-DMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELERKDQAEKGYSQQL 1438
Query: 659 KKQIEDLNMTLEKLRSDLDEKETERSDMK--ETIFELEDEVEQHRAVKLHDNL-----II 711
++ LN T K +E E SD+K + ++LE E H KL +
Sbjct: 1439 RELGRQLNQTTGK----AEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAH 1494
Query: 712 SDLENTVKKLQDQKHDM--EREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQ- 768
+ E ++ L Q H E+E++ L R+ QF+ + + +IK+E +
Sbjct: 1495 AVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQ---LLQNIKAEKEN 1551
Query: 769 -EEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQE 801
++I L L ++ E E L +++EE+ + E
Sbjct: 1552 NDKIQRLNEELEKSNECAEMLKQKVEELTRQNNE 1585
Score = 48.9 bits (115), Expect = 3e-05
Identities = 46/224 (20%), Positives = 106/224 (47%), Gaps = 18/224 (8%)
Query: 582 QLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQ 641
+LE E+ K + S H G SD+ ++ L+ K S L+ +A + +R++
Sbjct: 1101 RLEEEEIKRCKETSEH--GAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVE 1158
Query: 642 DAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHR 701
+ + KV + + ++ +ED+ +L+K+R++ + K+ R ELE V +
Sbjct: 1159 EELPKVREAAENELRKQQRNVEDI--SLQKIRAESEAKQYRR--------ELETIVREKE 1208
Query: 702 AVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIAN 761
A + + + + + ++ +E + +L E + R + L+ + N
Sbjct: 1209 AAERE----LERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLN 1264
Query: 762 DIKSEAQEEIGDLKRRLHEAQEKNEKLTKELE-EIKSRKQEEER 804
D++ + + + +L+R+ + +E+ KL K++E ++ +KQ E+
Sbjct: 1265 DLEQQKNKLMEELRRK-RDNEEELLKLIKQMEKDLAFQKQVAEK 1307
Score = 47.8 bits (112), Expect = 6e-05
Identities = 65/332 (19%), Positives = 141/332 (42%), Gaps = 31/332 (9%)
Query: 514 QHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQ 573
Q + T + +++ E + + + + IE +Q E+Y ATV +
Sbjct: 981 QQVETTQRKIQENQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYE 1040
Query: 574 IEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHT 633
++ +A ++++++ + + +S D IQ+ ++ + + L + + + +
Sbjct: 1041 LQTMTYRAMVDSQQKSPVKRRRMQSSADLI-IQEFMDL----RTRYTALVTLMTQYIKFA 1095
Query: 634 RNDANRLQD---AIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETI 690
+ RL++ K E+ A+ + ++Q + + KL + E E +++K+
Sbjct: 1096 GDSLKRLEEEEIKRCKETSEHGAYSDLLQRQKATV-LENSKLTGKISELERMVAELKKQK 1154
Query: 691 FELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRL----REESAEW 746
+E+E+ + R ++ + + V+ + QK E E K R L RE+ A
Sbjct: 1155 SRVEEELPKVREAAENE---LRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAE 1211
Query: 747 RQ--------FQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLT-KELEEIKS 797
R+ +A+ + A V N + Q E RR E K + L+ +LE+ K+
Sbjct: 1212 RELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKN 1271
Query: 798 RKQEEERGR------VYNYMNAVERDLAALRQ 823
+ EE R + + + +E+DLA +Q
Sbjct: 1272 KLMEELRRKRDNEEELLKLIKQMEKDLAFQKQ 1303
Score = 35.8 bits (81), Expect = 0.23
Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 13/135 (9%)
Query: 575 EMNRLKAQLENEKQKVAELYS-IHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHT 633
E+ RLK L K E +S S ++ L V + + +++S+ + L
Sbjct: 789 ELERLKDDLGTITNKCEEFFSQAAASSSVPTLRSELNVVLQNMNQVYSMSSTYIDKLKTV 848
Query: 634 RNDANRLQDAIAKVE-DEYRAFQEEA----KKQIEDLNMTLEKLRSDLDEKETERSDMKE 688
Q A A V+ E + +EEA K IE+L TL++ RS++DEK ++
Sbjct: 849 NLVLKNTQAAEALVKLYETKLCEEEAVIADKNNIENLISTLKQWRSEVDEK-------RQ 901
Query: 689 TIFELEDEVEQHRAV 703
LEDE+++ +A+
Sbjct: 902 VFHALEDELQKAKAI 916
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 95.5 bits (236), Expect = 2e-19
Identities = 50/105 (47%), Positives = 67/105 (63%), Gaps = 2/105 (1%)
Query: 1012 SKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRN 1071
S ++ALL WCQ KT GY ++++TNF+SSW DGLAF AL+H + P I + +L + R N
Sbjct: 174 SAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHN 233
Query: 1072 FMLAFQAAE-SVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYF 1115
AF AE +GI LD E V TE PD ++++ YV A Y YF
Sbjct: 234 LEHAFNVAERQLGIIPLLD-PEDVFTENPDEKSIITYVVAFYHYF 277
Score = 37.7 bits (86), Expect = 0.061
Identities = 100/478 (20%), Positives = 182/478 (38%), Gaps = 92/478 (19%)
Query: 406 NQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEY 465
N H+ + QA + ELA + + +++E ++L +EK + S KLE R +
Sbjct: 1307 NLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDEKP---QFTALVSQKLEALHRLWDE 1363
Query: 466 FRSLLDE--HHISYVIDEDVKSGRYMELEQRYMDLAENARFER--EQLLGVQQHLSNTLK 521
++ E H+S D++ + +L + + + R + + L V + L+ +
Sbjct: 1364 LQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQLRSDDPGKDLTSVNRMLAKLKR 1423
Query: 522 MAEQDNKEAQEM------IGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIE 575
+ +Q N +E+ + ++ E + IE K L L K + S + +
Sbjct: 1424 VEDQVNVRKEELGELFAQVPSMGEEGGDADLSIE---KRFLDLLEPLGRRKKQLESSRAK 1480
Query: 576 MNRLKAQLENEKQKVAELYSIHNSGDKSD-------------------------IQDLLE 610
+ ++ LE+E V E + S D ++D+L+
Sbjct: 1481 L-QISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQ 1539
Query: 611 SVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLE 670
+ E AE L+E L H ++ +RL++A A +++ L E
Sbjct: 1540 RGQQLVEAAEIDCQDLEERLGHLQSSWDRLREA--------------AAGRLQRLRDANE 1585
Query: 671 KLRSDLDEKETERSDMKETIFELEDEV---EQHRAVKLHDNLIISDLENTVKKLQDQKHD 727
+ LD E E ++ ++ + DE+ E+ V L +L + Q D
Sbjct: 1586 AQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHL----------RQQRAVED 1635
Query: 728 MEREIKTLHRRLR---------EESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRL 778
R IK L R + E Q Q D A +K A+E L+
Sbjct: 1636 YGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYA-----GLKDVAEERKRKLENMY 1690
Query: 779 HEAQEKNEKLTKELEEIKSRKQ----EEERGRVYNYMNAVE---RDLAALRQGMGLSR 829
H Q K E T +LE+ S K+ E G+ ++++ + RD A +G R
Sbjct: 1691 HLFQLKRE--TDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQER 1746
Score = 32.3 bits (72), Expect = 2.6
Identities = 60/335 (17%), Positives = 126/335 (37%), Gaps = 33/335 (9%)
Query: 479 IDEDVKS--GRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGA 536
++ DV + R LE+ L ++ ++E + Q+HL + +Q + ++++G
Sbjct: 1000 LERDVAAIQARVDALERESQQLMDSHPEQKEDIGQRQKHLEELWQGLQQSLQGQEDLLGE 1059
Query: 537 LKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYS- 595
+ + ++ + + + A E + ++ + A +++E + Y
Sbjct: 1060 VSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQHAGIKDEIDGHQDSYQR 1119
Query: 596 IHNSGDK-----SDIQDLLESVRLD-------------KEKAETLASSLQEDLAHTRNDA 637
+ SG+K +D + LL RL+ + ++ TLA L + DA
Sbjct: 1120 VKESGEKVIQGQTDPEYLLLGQRLEGLDTGWNALGRMWESRSHTLAQCL--GFQEFQKDA 1177
Query: 638 NRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEV 697
+ + ++ EY E +E + K L E R ++ V
Sbjct: 1178 KQAEAILSN--QEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRD-------KVLSPV 1228
Query: 698 EQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAV 757
+ + NL ++ V+ ++D +H E L ++ E + F + Q
Sbjct: 1229 DSGNKLVAEGNLYSDKIKEKVQLIED-RHRKNNEKAQEASVLLRDNLELQNFLQNCQELT 1287
Query: 758 VIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKEL 792
+ ND +Q+ D R LH K++ EL
Sbjct: 1288 LWINDKLLTSQDVSYDEARNLHNKWLKHQAFVAEL 1322
>gi|67782319 spectrin beta isoform b [Homo sapiens]
Length = 2137
Score = 95.5 bits (236), Expect = 2e-19
Identities = 50/105 (47%), Positives = 67/105 (63%), Gaps = 2/105 (1%)
Query: 1012 SKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIPYQELNSQDKRRN 1071
S ++ALL WCQ KT GY ++++TNF+SSW DGLAF AL+H + P I + +L + R N
Sbjct: 174 SAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHN 233
Query: 1072 FMLAFQAAE-SVGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYF 1115
AF AE +GI LD E V TE PD ++++ YV A Y YF
Sbjct: 234 LEHAFNVAERQLGIIPLLD-PEDVFTENPDEKSIITYVVAFYHYF 277
Score = 37.7 bits (86), Expect = 0.061
Identities = 100/478 (20%), Positives = 182/478 (38%), Gaps = 92/478 (19%)
Query: 406 NQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEY 465
N H+ + QA + ELA + + +++E ++L +EK + S KLE R +
Sbjct: 1307 NLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDEKP---QFTALVSQKLEALHRLWDE 1363
Query: 466 FRSLLDE--HHISYVIDEDVKSGRYMELEQRYMDLAENARFER--EQLLGVQQHLSNTLK 521
++ E H+S D++ + +L + + + R + + L V + L+ +
Sbjct: 1364 LQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQLRSDDPGKDLTSVNRMLAKLKR 1423
Query: 522 MAEQDNKEAQEM------IGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIE 575
+ +Q N +E+ + ++ E + IE K L L K + S + +
Sbjct: 1424 VEDQVNVRKEELGELFAQVPSMGEEGGDADLSIE---KRFLDLLEPLGRRKKQLESSRAK 1480
Query: 576 MNRLKAQLENEKQKVAELYSIHNSGDKSD-------------------------IQDLLE 610
+ ++ LE+E V E + S D ++D+L+
Sbjct: 1481 L-QISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQ 1539
Query: 611 SVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLE 670
+ E AE L+E L H ++ +RL++A A +++ L E
Sbjct: 1540 RGQQLVEAAEIDCQDLEERLGHLQSSWDRLREA--------------AAGRLQRLRDANE 1585
Query: 671 KLRSDLDEKETERSDMKETIFELEDEV---EQHRAVKLHDNLIISDLENTVKKLQDQKHD 727
+ LD E E ++ ++ + DE+ E+ V L +L + Q D
Sbjct: 1586 AQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHL----------RQQRAVED 1635
Query: 728 MEREIKTLHRRLR---------EESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRL 778
R IK L R + E Q Q D A +K A+E L+
Sbjct: 1636 YGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYA-----GLKDVAEERKRKLENMY 1690
Query: 779 HEAQEKNEKLTKELEEIKSRKQ----EEERGRVYNYMNAVE---RDLAALRQGMGLSR 829
H Q K E T +LE+ S K+ E G+ ++++ + RD A +G R
Sbjct: 1691 HLFQLKRE--TDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQER 1746
Score = 32.3 bits (72), Expect = 2.6
Identities = 60/335 (17%), Positives = 126/335 (37%), Gaps = 33/335 (9%)
Query: 479 IDEDVKS--GRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGA 536
++ DV + R LE+ L ++ ++E + Q+HL + +Q + ++++G
Sbjct: 1000 LERDVAAIQARVDALERESQQLMDSHPEQKEDIGQRQKHLEELWQGLQQSLQGQEDLLGE 1059
Query: 537 LKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYS- 595
+ + ++ + + + A E + ++ + A +++E + Y
Sbjct: 1060 VSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQHAGIKDEIDGHQDSYQR 1119
Query: 596 IHNSGDK-----SDIQDLLESVRLD-------------KEKAETLASSLQEDLAHTRNDA 637
+ SG+K +D + LL RL+ + ++ TLA L + DA
Sbjct: 1120 VKESGEKVIQGQTDPEYLLLGQRLEGLDTGWNALGRMWESRSHTLAQCL--GFQEFQKDA 1177
Query: 638 NRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEV 697
+ + ++ EY E +E + K L E R ++ V
Sbjct: 1178 KQAEAILSN--QEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRD-------KVLSPV 1228
Query: 698 EQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAV 757
+ + NL ++ V+ ++D +H E L ++ E + F + Q
Sbjct: 1229 DSGNKLVAEGNLYSDKIKEKVQLIED-RHRKNNEKAQEASVLLRDNLELQNFLQNCQELT 1287
Query: 758 VIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKEL 792
+ ND +Q+ D R LH K++ EL
Sbjct: 1288 LWINDKLLTSQDVSYDEARNLHNKWLKHQAFVAEL 1322
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 93.6 bits (231), Expect = 9e-19
Identities = 133/710 (18%), Positives = 300/710 (42%), Gaps = 80/710 (11%)
Query: 124 ERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAA--L 181
++L E S +L + A ++A + + ++ + R+ K + Q ++A L
Sbjct: 1001 KKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKL 1060
Query: 182 EAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGD-EKSEKETIMAHQPTDV- 239
+ + DL +I L+ ++ +++ QL E+ +G + + ET+ + V
Sbjct: 1061 DGETTDLQD-------QIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVV 1113
Query: 240 ---ESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSP 296
++ + +LQE + + N+ + + R L + L AL LE LD + +
Sbjct: 1114 RELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTT-------AAQQ 1166
Query: 297 EITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPL 356
E+ + + V +L E +H+ ++ ++ Q
Sbjct: 1167 ELRTKREQE----------------VAELKKALEEETKNHE---------AQIQDMRQRH 1201
Query: 357 TSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQA 416
++ + L ++E++++G + E+ AC + + Q++ ++L A
Sbjct: 1202 ATALEELSEQLEQAKRFKANLEKNKQGLETDNKEL--ACEVKVLQQVKAESEHKRKKLDA 1259
Query: 417 TLQEL----ADLQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDE 472
+QEL ++ ++ EL + +L E + L + K F++ S L +
Sbjct: 1260 QVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQD 1319
Query: 473 HHISYVIDEDVK-----SGRYMELEQRYMDLAENARFERE-------QLLGVQQHLSNTL 520
++ E+ + S R +LE+ L E E E Q+L +Q L++T
Sbjct: 1320 --TQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Query: 521 KMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLK 580
K + D + + A K+ E + + ++ KA LE+ K + Q E++ L
Sbjct: 1378 KKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE-KALAYDKLEKTKNRL---QQELDDLT 1433
Query: 581 AQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQED-----LAHTRN 635
L++++Q + L D+ ++ S R +E+ A + +++ LA
Sbjct: 1434 VDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALE 1493
Query: 636 DANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELED 695
+A ++ + + RA E+ +D+ + +L E + +M+ + ELED
Sbjct: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELED 1553
Query: 696 EVEQHRAVKLHDNLIISDLENTVKK-LQDQKHDMEREIKTLHRRLREESAEWRQFQADLQ 754
E++ KL + + ++ ++ LQ + E + + L +++RE AE + Q
Sbjct: 1554 ELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERK--Q 1611
Query: 755 TAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEER 804
A+ +A+ K E ++ DL+ ++ A + +++ K+L +++++ ++ +R
Sbjct: 1612 RALAVASKKKMEI--DLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659
Score = 92.0 bits (227), Expect = 3e-18
Identities = 136/662 (20%), Positives = 286/662 (43%), Gaps = 83/662 (12%)
Query: 177 DRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQP 236
D A+LE++++D L + + + L+L + +R + + ++ E +E++ K + Q
Sbjct: 1309 DAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN--LEKQV 1366
Query: 237 TDVESTLLQLQEQNTAIREELNQLKN----ENRMLKDRLNALGFSLEQRLDNSEKLFGYQ 292
++S QL + + ++L +++ + ++LKD +L QRL+ EK Y
Sbjct: 1367 LALQS---QLADTKKKVDDDLGTIESLEEAKKKLLKD-----AEALSQRLE--EKALAYD 1416
Query: 293 SLSPEITPDNQSDGGGTLTSSVEGSAPGSVE------DLLSQDENTLMDHQHSNSMDNLD 346
L Q T+ + ++E D L +E ++ +++ D +
Sbjct: 1417 KLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI-SARYAEERDRAE 1475
Query: 347 SECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEV--SVACLTERIHQME 404
+E E S AL+ ++ E ER K + ++ S + + +H++E
Sbjct: 1476 AEAREKETKALSLARALEEALEAKEE----FERQNKQLRADMEDLMSSKDDVGKNVHELE 1531
Query: 405 ENQHSTS---EELQATLQELADLQQITQ------ELNSENERLGEEKVILMESLCQQSDK 455
+++ + EE++ L+EL D Q T+ E+N + + E+ + Q +K
Sbjct: 1532 KSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE-QNEEK 1590
Query: 456 LEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLA-ENARFEREQLLGVQQ 514
+Q+ + L++ + V S + ME++ + ++ E A R++++ +
Sbjct: 1591 KRLLIKQVRELEAELEDERKQRALA--VASKKKMEIDLKDLEAQIEAANKARDEVIKQLR 1648
Query: 515 HLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQI 574
L +K +++ +EA+ R + ESE+K K+ A L+ + +S+
Sbjct: 1649 KLQAQMKDYQRELEEARA------SRDEIFAQSKESEKKLKSLEAEILQLQEELASSE-- 1700
Query: 575 EMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTR 634
R + E E+ ++A+ + SG KS + D +K + E + L+E+L +
Sbjct: 1701 ---RARRHAEQERDELADEITNSASG-KSALLD-------EKRRLEARIAQLEEELEEEQ 1749
Query: 635 NDANRLQDAIAKVE------DEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETE-----R 683
++ L D K + A + A ++ ++ LE+ +L K E +
Sbjct: 1750 SNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVK 1809
Query: 684 SDMKETIF-------ELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLH 736
S K TI +LE+++EQ + N ++ E +K++ Q D R
Sbjct: 1810 SKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYK 1869
Query: 737 RRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIK 796
++ + +A +Q + L+ A + + A L+R L +A E NE L++E+ +K
Sbjct: 1870 EQMEKANARMKQLKRQLEE----AEEEATRANASRRKLQRELDDATEANEGLSREVSTLK 1925
Query: 797 SR 798
+R
Sbjct: 1926 NR 1927
Score = 86.3 bits (212), Expect = 2e-16
Identities = 165/798 (20%), Positives = 327/798 (40%), Gaps = 127/798 (15%)
Query: 150 LAKRSRSRTATECDVRMSKSKSDNQISDR----AALEAKVKDL-LTLAKTK--------- 195
L +R + T ++ +K K D + +D A L+A++ +L L LAK +
Sbjct: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
Query: 196 -DVEILHLRNEL---RDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNT 251
D E LH N L R+++AQ+ ++ E ++ S + ++Q
Sbjct: 1099 GDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA----------------EKQKR 1142
Query: 252 AIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLT 311
+ EEL LK E L+D L+ E R +++ + E T ++++
Sbjct: 1143 DLSEELEALKTE---LEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ-----I 1194
Query: 312 SSVEGSAPGSVEDLLSQDENT------LMDHQHSNSMDNLDSECS-EVYQPLTSSDDALD 364
+ ++E+L Q E L ++ DN + C +V Q + + +
Sbjct: 1195 QDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1254
Query: 365 APSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQ--------- 415
++ + E K S G+ V +A ++ +N + EE +
Sbjct: 1255 KKLDAQVQ-----ELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD 1309
Query: 416 -ATLQ-ELADLQQITQE-------LNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYF 466
A+L+ +L D Q++ QE L+S +L EEK L E ++ + ++ +Q+
Sbjct: 1310 AASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLAL 1369
Query: 467 RSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENA-----RFER-----EQLLGVQQHL 516
+S L + +D+D+ G LE+ L ++A R E ++L + L
Sbjct: 1370 QSQLAD--TKKKVDDDL--GTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 517 SNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEM 576
L D +++ L+++ ++++ E+ A A + +A + +
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA 1485
Query: 577 NRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRND 636
L LE E + E + N ++D++DL+ S K+ L++
Sbjct: 1486 LSLARALE-EALEAKEEFERQNKQLRADMEDLMSS----KDDVGKNVHELEKSKRALEQQ 1540
Query: 637 ANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLR--SDLDEKETERSDMKETIF--- 691
++ + ++EDE +A E+AK ++E +NM K + DL ++ + + K +
Sbjct: 1541 VEEMRTQLEELEDELQA-TEDAKLRLE-VNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV 1598
Query: 692 -ELEDEVEQHR-------AVKLHDNLIISDLENTV--------------KKLQDQKHDME 729
ELE E+E R A K + + DLE + +KLQ Q D +
Sbjct: 1599 RELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQ 1658
Query: 730 REIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLT 789
RE++ E A+ ++ + L++ + +I + QEE+ +R A+++ ++L
Sbjct: 1659 RELEEARASRDEIFAQSKESEKKLKS---LEAEI-LQLQEELASSERARRHAEQERDELA 1714
Query: 790 KELEEIKSRKQE--EERGRVYNYMNAVERDLAALRQGMG-LSRRSSTSSEPTPTVKTLIK 846
E+ S K +E+ R+ + +E +L + M L+ R ++ T+ +
Sbjct: 1715 DEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1774
Query: 847 SFDSASQVPNPAAAAIPR 864
+ SA+Q + A + R
Sbjct: 1775 AERSAAQKSDNARQQLER 1792
Score = 85.1 bits (209), Expect = 3e-16
Identities = 97/449 (21%), Positives = 205/449 (45%), Gaps = 58/449 (12%)
Query: 399 RIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSD---K 455
++ + EE + EEL ++ ++ +E+ ++++L EEK IL E L +++ +
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905
Query: 456 LEHFSRQIEYFRSLLDE--HHISYVIDEDVKSGRYMELEQRYMDL-AENARFEREQLLGV 512
E ++ + L+E H + ++E+ + + ++ E++ M ++ + ++ G
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965
Query: 513 QQHLSNTLKMAEQDNKEAQEMIGAL--------KERSHHMERIIE-----SEQKGKAALA 559
+Q L AE K+ +E I L KE+ +RI E +E++ KA
Sbjct: 966 RQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNL 1025
Query: 560 ATLEEYKATVASDQIEM----NRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLD 615
A + + + SD E + + +LE K+K+ G+ +D+QD + ++
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKL--------DGETTDLQDQIAELQAQ 1077
Query: 616 KEKAETLASSLQEDL--AHTRND------------ANRLQDAIAKVEDEY---RAFQEEA 658
++ + + +E+L A R D LQ IA++++++ +A + +A
Sbjct: 1078 IDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA 1137
Query: 659 KKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTV 718
+KQ DL+ LE L+++L++ + +E + E EV + + LE
Sbjct: 1138 EKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKA----------LEEET 1187
Query: 719 KKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRL 778
K + Q DM + T L E+ + ++F+A+L+ E E+ L++
Sbjct: 1188 KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1247
Query: 779 HEAQEKNEKLTKELEEIKSRKQEEERGRV 807
E++ K +KL +++E+ ++ E +R RV
Sbjct: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
Score = 82.4 bits (202), Expect = 2e-15
Identities = 142/691 (20%), Positives = 288/691 (41%), Gaps = 117/691 (16%)
Query: 164 VRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILH--LRNELRDMRAQLGINEDHSE 221
+++++ + + Q D L+ K K + +++E H L E + QL +
Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904
Query: 222 GDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQ-LKNENRMLKDRLNALGFSLEQ 280
E E +A + ++E L L E EE NQ L+NE + ++ + LE+
Sbjct: 905 --EAEEMRARLAAKKQELEEILHDL-ESRVEEEEERNQILQNEKKKMQAHIQ----DLEE 957
Query: 281 RLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSN 340
+LD E Q L E + E E++L ++ +
Sbjct: 958 QLDEEEG--ARQKLQLE-------------KVTAEAKIKKMEEEILLLEDQNSKFIKEKK 1002
Query: 341 SMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERI 400
M++ +ECS + + E E ++ + R N EV ++ L ER+
Sbjct: 1003 LMEDRIAECS--------------SQLAEEEEKAKNLAKIR-----NKQEVMISDLEERL 1043
Query: 401 HQMEENQHSTSEELQATLQELADLQQITQELNSENE----RLGEEKVILMESLCQQSDKL 456
+ E+ + + + E DLQ EL ++ + +L +++ L +L + D+
Sbjct: 1044 KKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDET 1103
Query: 457 EHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAEN---ARFEREQLLGV- 512
H + ++ R L + E K+ R + E++ DL+E + E E L
Sbjct: 1104 LHKNNALKVVRELQAQIAELQEDFESEKASR-NKAEKQKRDLSEELEALKTELEDTLDTT 1162
Query: 513 ----------QQHLSNTLKMAEQDNKEAQEMIGALKER-SHHMERIIESEQKGKAALAAT 561
+Q ++ K E++ K + I +++R + +E + E ++ K A
Sbjct: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAK-RFKAN 1221
Query: 562 LEEYKATVASDQIE-------MNRLKAQLENEKQK----VAELYSIHNSGDK-------- 602
LE+ K + +D E + ++KA+ E++++K V EL++ + GD+
Sbjct: 1222 LEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1281
Query: 603 -SDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQ 661
S +Q+ L++V E+AE +D A ++LQD +++E R + +
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLE---SQLQDTQELLQEETRQ-KLNLSSR 1337
Query: 662 IEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKL 721
I L L+ +E+E R ++++ + L+ ++ + K+ D+L T++ L
Sbjct: 1338 IRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKK-KVDDDL------GTIESL 1390
Query: 722 QDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDL------- 774
++ K + ++ + L +RL E++ + + + K+ Q+E+ DL
Sbjct: 1391 EEAKKKLLKDAEALSQRLEEKALAYDKLE-----------KTKNRLQQELDDLTVDLDHQ 1439
Query: 775 ---KRRLHEAQEKNEKLTKELEEIKSRKQEE 802
L + Q+K ++L E + I +R EE
Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEE 1470
Score = 77.4 bits (189), Expect = 7e-14
Identities = 128/720 (17%), Positives = 292/720 (40%), Gaps = 76/720 (10%)
Query: 118 ESSSTRERLRERTRLNQSKKLPSAGQGANDM--ALAKRSRSRTATECDVRMSKSKSDNQI 175
ES E+ + + S++L + D A + RT E +V K + +
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
Query: 176 SDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQ 235
+ EA+++D+ T E+ + + +A L N+ E D K + Q
Sbjct: 1188 KNH---EAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQ 1244
Query: 236 PTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLS 295
ES +++ A +EL+ +E L+ L L+ LDN L
Sbjct: 1245 QVKAESE--HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLE----E 1298
Query: 296 PEITPDNQSDGGGTLTSSVEGSAPGSVEDL------------LSQDENTLMDHQHSN--S 341
E + +L S ++ + E+ L +++N+L + Q +
Sbjct: 1299 AEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEA 1358
Query: 342 MDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERI- 400
NL+ + + L + +D + I S+E ++K +A +S + +
Sbjct: 1359 RKNLEKQVLALQSQLADTKKKVDDDLGT----IESLEEAKKKLLKDAEALSQRLEEKALA 1414
Query: 401 -HQMEENQHSTSEELQATLQELADLQQITQELNSENER----LGEEKVILMESLCQQSDK 455
++E+ ++ +EL +L +Q+ L + ++ L EEK I ++ D+
Sbjct: 1415 YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISAR-YAEERDR 1473
Query: 456 LEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQH 515
E +R+ E ++L ++ ++E +++ E + + + R + E L+ +
Sbjct: 1474 AEAEAREKET-KAL----SLARALEEALEAKEEFERQNKQL------RADMEDLMSSKDD 1522
Query: 516 LSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIE 575
+ + E+ + ++ + ++ + +E +++ + K L ++ KA Q E
Sbjct: 1523 VGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKA-----QFE 1577
Query: 576 MNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQ-----EDL 630
+ +NE++K + + +++ LE R K++A +AS + +DL
Sbjct: 1578 RDLQTRDEQNEEKKRLLIKQVR------ELEAELEDER--KQRALAVASKKKMEIDLKDL 1629
Query: 631 AHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETI 690
AN+ +D + K + +A ++ ++++E+ + +++ + E E + ++ I
Sbjct: 1630 EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEI 1689
Query: 691 FELEDEVEQHRAVKLH-----DNLI--ISDLENTVKKLQDQKHDMEREIKTLHRRLREES 743
+L++E+ + H D L I++ + L D+K +E I L L EE
Sbjct: 1690 LQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQ 1749
Query: 744 AEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEE 803
+ + + + + +E E + ++ ++L ++ +E+K++ QE E
Sbjct: 1750 SNMELLNDRFRKTTLQVDTLNAELAAE----RSAAQKSDNARQQLERQNKELKAKLQELE 1805
Score = 62.0 bits (149), Expect = 3e-09
Identities = 86/374 (22%), Positives = 159/374 (42%), Gaps = 71/374 (18%)
Query: 505 EREQLLGVQQHLSNTLKMAEQDNK---EAQEMIGALKERSHHM----ERIIESEQKGKAA 557
+ E+L + L LK+ E+ K E +EM ER H + I+ + + +
Sbjct: 850 QEEELQAKDEEL---LKVKEKQTKVEGELEEM-----ERKHQQLLEEKNILAEQLQAETE 901
Query: 558 LAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDK---SDIQDLLESV-- 612
L A EE +A +A+ + E+ + LE+ ++ E I + K + IQDL E +
Sbjct: 902 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 961
Query: 613 --------RLDKEKAETLASSLQEDLAHTRNDANR-------LQDAIAKVEDEYRAFQEE 657
+L+K AE ++E++ + ++ ++D IA+ + A +EE
Sbjct: 962 EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQL-AEEEE 1020
Query: 658 AKKQIEDLNMTLEKLRSDLDEK----ETERSDMKETIFELEDEVEQHRAVKLHDNLIISD 713
K + + E + SDL+E+ E R ++++ +L+ E L D I++
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTD-----LQDQ--IAE 1073
Query: 714 LENTVKKLQDQKHDMEREIK---------TLHRR-----LREESAEWRQFQADLQTAVVI 759
L+ + +L+ Q E E++ TLH+ +RE A+ + Q D ++
Sbjct: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKAS 1133
Query: 760 ANDI---KSEAQEEIGDLKRRLHEA-------QEKNEKLTKELEEIKSRKQEEERGRVYN 809
N K + EE+ LK L + QE K +E+ E+K +EE +
Sbjct: 1134 RNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQ 1193
Query: 810 YMNAVERDLAALRQ 823
+ +R AL +
Sbjct: 1194 IQDMRQRHATALEE 1207
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 93.6 bits (231), Expect = 9e-19
Identities = 169/832 (20%), Positives = 322/832 (38%), Gaps = 119/832 (14%)
Query: 105 ASSTKRSTSTGNKESSSTRERLR--ERTRLNQSKKLPSAGQGANDMALAKRSRSRTATEC 162
++ T++ +T +E +E L E R +K+ S Q ND+ L ++ +
Sbjct: 844 SAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDA 903
Query: 163 DVRMSKSKSDNQISDRAALEAKVKDL-------------LTLAKTK-DVEILHLRNELRD 208
+ R D I ++ LEAKVK++ LT K K + E L+ ++ D
Sbjct: 904 EERC-----DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDD 958
Query: 209 MRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLK 268
+ L E E K + + ++ + +L ++ A++E Q ++ ++ +
Sbjct: 959 LELTLAKVEKEKHATENKVKN--LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEE 1016
Query: 269 DRLNALGFS---LEQRLDNSE------------------KLFGYQSLSPEITPDNQSDGG 307
D++N+L S LEQ++D+ E KL G L+ E D ++D
Sbjct: 1017 DKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKL 1076
Query: 308 GTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPS 367
+ + ++ +DE L +N + E+ + L + A
Sbjct: 1077 QLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKEN-QARIEELEEELEAERTARAKVE 1135
Query: 368 SSESEGIPSIER--SRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQ------ 419
S+ +E R +G A+ V + +R + ++ + E ATLQ
Sbjct: 1136 KLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE---ATLQHEATAA 1192
Query: 420 ---------------ELADLQQITQELNSENERLG---EEKVILMESLCQQSDKLEHFSR 461
++ +LQ++ Q+L E ++ ME + + LE SR
Sbjct: 1193 ALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSR 1252
Query: 462 QIE----YFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQL-------- 509
+E +R L+E S D + R +L+ +LA E+E L
Sbjct: 1253 TLEDQANEYRVKLEEAQRSL---NDFTTQR-AKLQTENGELARQLE-EKEALISQLTRGK 1307
Query: 510 LGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERI---IESEQKGKAALAATLEEYK 566
L Q + + + E++ K + AL+ H + + E E + KA L L +
Sbjct: 1308 LSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKAN 1367
Query: 567 ATVAS--DQIEMNRLK--AQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETL 622
+ VA + E + ++ +LE K+K+A+ D ++ +E+V E
Sbjct: 1368 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRL--------QDAEEAVEAVNAKCSSLEKT 1419
Query: 623 ASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQE---EAKKQIEDLNMTLEKLRSDLDEK 679
LQ ++ D R A A ++ + R F + E K++ E+ LE + +
Sbjct: 1420 KHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSL 1479
Query: 680 ETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLE-------NTVKKLQDQKHDMEREI 732
TE +K E + +E + + ISDL V +L+ + +E E
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEK 1539
Query: 733 KTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKEL 792
L L E A + + A + N IK+E + ++ + + +A+ ++++ L
Sbjct: 1540 LELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSL 1599
Query: 793 EEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTL 844
+ + R V +E DL + + LS + ++E VK+L
Sbjct: 1600 -QTSLDAETRSRNEVLRVKKKMEGDLNEME--IQLSHANRMAAEAQKQVKSL 1648
Score = 85.5 bits (210), Expect = 3e-16
Identities = 88/348 (25%), Positives = 164/348 (47%), Gaps = 48/348 (13%)
Query: 483 VKSGRYMELEQRYMDLAENARFEREQLLGVQQ--HLSNTLKMAEQDNKEAQEMIGALKER 540
VK+ +M+L + L ++A E+E ++ + TL+ +E KE +E + +L +
Sbjct: 826 VKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQE 885
Query: 541 SHHMERIIESEQ--------------KGKAALAATLEEYKATVASDQIEMNRLKAQLENE 586
+ ++ +++EQ K K L A ++E + D+ EMN A+L +
Sbjct: 886 KNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERL-EDEEEMN---AELTAK 941
Query: 587 KQKVAELYSIHNSGDKSDIQDL---LESVRLDKEKAETLASSLQEDLAHTRNDANRLQDA 643
K+K+ + S K DI DL L V +K E +L E++A L +
Sbjct: 942 KRKLED----ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG-------LDEI 990
Query: 644 IAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAV 703
IAK+ E +A QE ++ ++DL + +K+ S + +++ + +LE +EQ + V
Sbjct: 991 IAKLTKEKKALQEAHQQALDDLQVEEDKVNS----LSKSKVKLEQQVDDLEGSLEQEKKV 1046
Query: 704 KLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDI 763
++ LE +K Q+ D+E + L +L+++ + Q + ++ V+A +
Sbjct: 1047 RMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQL 1106
Query: 764 K---SEAQEEIGDLKRRL---HEAQEKNEK----LTKELEEIKSRKQE 801
+ E Q I +L+ L A+ K EK L++ELEEI R +E
Sbjct: 1107 QKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEE 1154
Score = 79.3 bits (194), Expect = 2e-14
Identities = 172/818 (21%), Positives = 328/818 (40%), Gaps = 145/818 (17%)
Query: 105 ASSTKRSTSTGNKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDV 164
A K +T NK + T E + + K A Q A+ AL D+
Sbjct: 964 AKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALD-----------DL 1012
Query: 165 RMSKSKSDNQISDRAALEAKVKDLL-TLAKTKDVEILHLRNELRDMRAQLGINEDHSEGD 223
++ + K ++ + LE +V DL +L + K V R +L + +L EGD
Sbjct: 1013 QVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKV-----RMDLERAKRKL-------EGD 1060
Query: 224 EKSEKETIMAHQPTDVESTLLQLQE-----------QNTAIREE---LNQLKNENRMLKD 269
K +E+IM D+E+ LQL+E QN+ I +E QL+ + + +
Sbjct: 1061 LKLTQESIM-----DLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQA 1115
Query: 270 RLNALGFSLEQRLD---NSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVE-DL 325
R+ L LE EKL S E + + GG + +E + E
Sbjct: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1175
Query: 326 LSQD-ENTLMDHQ---------HSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIP 375
+ +D E + H+ H++S+ L + + Q + + + E + +
Sbjct: 1176 MRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNL-QRVKQKLEKEKSEFKLELDDVT 1234
Query: 376 SIERSRKGSSGNASEVSVACLTERIHQMEENQHSTS-EELQATLQELADLQQITQELNSE 434
S + N +VS R + + N++ EE Q +L + + Q N E
Sbjct: 1235 SNMEQIIKAKANLEKVS------RTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGE 1288
Query: 435 NERLGEEKVILMESLCQ----QSDKLEHFSRQIE--------YFRSLLDEHHISYVIDED 482
R EEK L+ L + + ++E RQ+E +L H ++ E
Sbjct: 1289 LARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQ 1348
Query: 483 VKSGRYMELE-QRYMDLAEN------ARFEREQLLGVQQHLSNTLKMAE--QDNKEAQEM 533
+ + E QR + A + ++E + + ++ K+A+ QD +EA E
Sbjct: 1349 YEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEA 1408
Query: 534 IGA----LKERSHHMERIIES----EQKGKAALAAT----------LEEYKATVASDQIE 575
+ A L++ H ++ IE ++ AA AA L E+K Q E
Sbjct: 1409 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 1468
Query: 576 MNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRN 635
L++ + + EL+ + N+ ++S + LE+ + + + + S L E L
Sbjct: 1469 ---LESSQKEARSLSTELFKLKNAYEES--LEHLETFKRENKNLQEEISDLTEQLGEGGK 1523
Query: 636 DANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEK-----LRSDLDEKETERSDMKETI 690
+ + L+ KV + + E + +E+ +LE LR+ L+ + +++++ +
Sbjct: 1524 NVHELE----KVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQI-KAEIERKL 1578
Query: 691 FELEDEVEQHRAVKLHDNLIISDLENTV--------------KKLQDQKHDMEREIKTLH 736
E ++E+EQ K + ++ L+ ++ KK++ ++ME ++ +
Sbjct: 1579 AEKDEEMEQ---AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHAN 1635
Query: 737 RRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIK 796
R E + + Q+ L+ + +D A DLK + + +N L ELEE++
Sbjct: 1636 RMAAEAQKQVKSLQSLLKDTQIQLDD----AVRANDDLKENIAIVERRNNLLQAELEELR 1691
Query: 797 SRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTS 834
+ ++ ER R E++L + + L +TS
Sbjct: 1692 AVVEQTERSR-----KLAEQELIETSERVQLLHSQNTS 1724
Score = 67.4 bits (163), Expect = 7e-11
Identities = 140/719 (19%), Positives = 291/719 (40%), Gaps = 96/719 (13%)
Query: 1 MKKASRSVGSVPKVSAISKTQTAEKIKPENSSSASTGGKLVKPGTAASLSKTKSSDDLLA 60
+++A RS+ A +T+ E + A L+ T LS T+ +DL
Sbjct: 1265 LEEAQRSLNDFTTQRAKLQTENGELARQLEEKEA-----LISQLTRGKLSYTQQMEDLKR 1319
Query: 61 GMAGGVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGNKESS 120
+ +GK + A ++ + + + T + +R S N E +
Sbjct: 1320 QLEE--------EGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVA 1371
Query: 121 STRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISDRAA 180
R + E + ++++L A + LA+R + E V +K + +
Sbjct: 1372 QWRTKY-ETDAIQRTEELEEAKK-----KLAQRLQD---AEEAVEAVNAKCSSLEKTKHR 1422
Query: 181 LEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVE 240
L+ +++DL+ + + L + R+ L + E + +SE E+ + +
Sbjct: 1423 LQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE-ESQSELESSQK-EARSLS 1480
Query: 241 STLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKL-----------F 289
+ L +L+ E L K EN+ L++ ++ L L + N +L
Sbjct: 1481 TELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKL 1540
Query: 290 GYQSLSPEITPDNQSDGGGTLTSSVE-GSAPGSVEDLLSQDENTLMD--HQHSNSMDNLD 346
QS E + + G L + +E +E L++ + + H +D+L
Sbjct: 1541 ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Query: 347 SECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSG--NASEVSVACLTERIHQME 404
+ +LDA + S +E + R +K G N E+ ++ + +
Sbjct: 1601 T--------------SLDAETRSRNE----VLRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1642
Query: 405 ENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMES-------LCQQSDKLE 457
+ S L+ T +L D + +L EN + E + L+++ + +Q+++
Sbjct: 1643 KQVKSLQSLLKDTQIQLDDAVRANDDLK-ENIAIVERRNNLLQAELEELRAVVEQTERSR 1701
Query: 458 HFSRQ--IEYFR--SLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQ 513
+ Q IE LL + S + + +L+ + + R E+ +
Sbjct: 1702 KLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEK---AK 1758
Query: 514 QHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQ 573
+ +++ MAE+ KE ++ S H+ER+ ++ ++ L L+E ++Q
Sbjct: 1759 KAITDAAMMAEELKKE--------QDTSAHLERMKKNMEQTIKDLQHRLDE------AEQ 1804
Query: 574 IEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHT 633
I + K QL+ + +V EL + K + + + + +R + + + L +ED
Sbjct: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKRNAESV-KGMRKSERRIKELTYQTEED---- 1859
Query: 634 RNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRS---DLDEKETERSDMKET 689
+ + RLQD + K++ + +A++ +A++ E N L K R +LDE E ER+D+ E+
Sbjct: 1860 KKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAE-ERADIAES 1917
Score = 66.2 bits (160), Expect = 2e-10
Identities = 134/726 (18%), Positives = 288/726 (39%), Gaps = 83/726 (11%)
Query: 117 KESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQIS 176
+E++ E R + + G+ +++ K+ + +E + + S+ +
Sbjct: 1181 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNME-- 1238
Query: 177 DRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQP 236
++AK +L +++T + + R +L + AQ +N+ ++ + + +A Q
Sbjct: 1239 --QIIKAKA-NLEKVSRTLEDQANEYRVKLEE--AQRSLNDFTTQRAKLQTENGELARQL 1293
Query: 237 TDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSP 296
+ E+ + QL + +++ LK + NAL +L+ + + L
Sbjct: 1294 EEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEET 1353
Query: 297 EITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPL 356
E + Q V A V ++ E + Q + ++ + ++ Q
Sbjct: 1354 EAKAELQR---------VLSKANSEVAQWRTKYETDAI--QRTEELEEAKKKLAQRLQDA 1402
Query: 357 TSSDDALDAPSSS----------ESEGIP-SIERSRKGSSG------NASEVSVACLTER 399
+ +A++A SS E E + +ERS ++ N ++ L E
Sbjct: 1403 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI----LAEW 1458
Query: 400 IHQMEENQ---HSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKL 456
+ EE+Q S+ +E ++ EL L+ +E E E L E + +++L
Sbjct: 1459 KQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQL 1518
Query: 457 EHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHL 516
+ + + + + + + LE E + R QL Q
Sbjct: 1519 GEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEH------EEGKILRAQLEFNQIKA 1572
Query: 517 SNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEM 576
K+AE+D + Q +R+H +R+++S Q A + E + ++
Sbjct: 1573 EIERKLAEKDEEMEQA------KRNH--QRVVDSLQTSLDAETRSRNEVLRVKKKMEGDL 1624
Query: 577 NRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRND 636
N ++ QL + + AE S +Q LL+ ++ + A L+E++A
Sbjct: 1625 NEMEIQLSHANRMAAEAQKQVKS-----LQSLLKDTQIQLDDAVRANDDLKENIAIVERR 1679
Query: 637 ANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLR-------SDLDEKETERSDMKET 689
N LQ + ++ + K ++L T E+++ S +++K+ SD+ +
Sbjct: 1680 NNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQL 1739
Query: 690 IFELEDEVEQHRAVKLHDNLIISD---LENTVKKLQD-------QKHDMEREIKTLHRRL 739
E+E+ V++ R + I+D + +KK QD K +ME+ IK L RL
Sbjct: 1740 QSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL 1799
Query: 740 RE-ESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSR 798
E E + + LQ +++ E + E ++R E+ + K + ++E+ +
Sbjct: 1800 DEAEQIALKGGKKQLQKLEARVRELEGELEAE----QKRNAESVKGMRKSERRIKELTYQ 1855
Query: 799 KQEEER 804
+E+++
Sbjct: 1856 TEEDKK 1861
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 93.6 bits (231), Expect = 9e-19
Identities = 185/864 (21%), Positives = 342/864 (39%), Gaps = 144/864 (16%)
Query: 7 SVGSVPKVSAISKTQTAEKIKPENSSSAS--TGGKLVKPGTAASLSKTKSSDDLLAGMAG 64
S+G+ K KT TA + +++ S +G K + T S S T+++ DLL G
Sbjct: 486 SLGAQSKKEEEVKTATATLMLQNRATATSPDSGAKKISVKTFPSASNTQATPDLLKGQQE 545
Query: 65 GVTVTNGVKGKKSTCPSAAPSASAPAMTTVENKSKISTGTASSTKRSTSTGNKESSSTRE 124
TN K+ + ST +TKR +
Sbjct: 546 LTQQTNEETAKQ---------------ILYNYLKEGSTDNDDATKRKVNL---------- 580
Query: 125 RLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQISD-RAALEA 183
+ E+ + +S+ SA QG N ++ + T+ D+ KSK ++++ + L+
Sbjct: 581 -VFEKIQTLKSRAAGSA-QGNN------QACNSTSEVKDLLEQKSKLTIEVAELQRQLQL 632
Query: 184 KVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTL 243
+VK+ +++ E MRA L E S+ +EK E+ + + + + E L
Sbjct: 633 EVKNQ-----------QNIKEERERMRANL--EELRSQHNEKVEENSTLQQRLEESEGEL 679
Query: 244 LQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQ 303
+ E+ ++ E Q + E R L+D+L+ + L+ + ++ G +L E+ Q
Sbjct: 680 RKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKG--ALIEELLQAKQ 737
Query: 304 SDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDAL 363
D L + E EDLL + E L + + L E S Q + +
Sbjct: 738 -DLQDLLIAKEE------QEDLLRKRERELTALKGA-----LKEEVSSHDQEMDKLKEQY 785
Query: 364 DAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELAD 423
DA + E S+E + K +V L R + E++Q T ++ +E
Sbjct: 786 DAELQALRE---SVEEATK---------NVEVLASRSNTSEQDQAGTEMRVKLLQEENEK 833
Query: 424 LQQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDV 483
LQ ++EL +L + L + + L+ + +I L H E V
Sbjct: 834 LQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEAL--VHARKEEKEAV 891
Query: 484 KSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHH 543
+ R +E E E A+ Q Q+ LS LK + ++ + + ++ H
Sbjct: 892 SARRALENE------LEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWH 945
Query: 544 MERIIESEQKGKA-----------ALAATLEEYKATVASDQIEMNR-LKAQ-LENEKQKV 590
+ + IE QK A L L+EYK + EM R LK + LE EK ++
Sbjct: 946 LGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRL 1005
Query: 591 AELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDE 650
+ D L+E D ++A+ A + ++ L T D +A + ++D+
Sbjct: 1006 TAM-------KMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDD 1058
Query: 651 YRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVK------ 704
++ + ++ L M LE+ R++ D S +E + +L +E+ Q RA +
Sbjct: 1059 RSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECD 1118
Query: 705 ----------LHDNLI-------------ISDLENTVKKLQDQKHDMEREIKTLHRRLRE 741
L +I + +E + +L+D+ ER+ L R
Sbjct: 1119 KISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRR 1178
Query: 742 ESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEK-------NEKLTKELEE 794
+ ++ + + D K + + +KR++ EA+E+ +KL +ELEE
Sbjct: 1179 LERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEE 1238
Query: 795 IKSRKQEEERGRVYNYMNAVERDL 818
Q + + +N++++DL
Sbjct: 1239 -----QMDMNEHLQGQLNSMKKDL 1257
Score = 44.7 bits (104), Expect = 5e-04
Identities = 113/532 (21%), Positives = 210/532 (39%), Gaps = 76/532 (14%)
Query: 151 AKRSRSRTATECDVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMR 210
A R AT+ +V + S+S+ D+A E +VK L + ++ ++ EL
Sbjct: 791 ALRESVEEATK-NVEVLASRSNTSEQDQAGTEMRVK----LLQEENEKLQGRSEELERRV 845
Query: 211 AQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDR 270
AQL + +GDE KET+ + E + QL+E R+E + + R L++
Sbjct: 846 AQLQRQIEDLKGDEAKAKETLKKY-----EGEIRQLEEALVHARKEEKEAVSARRALENE 900
Query: 271 LNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSA--PGSVEDLLSQ 328
L A +L Q ++L + L E Q + L + +E G + L +
Sbjct: 901 LEAAQGNLSQTTQEQKQLS--EKLKEE---SEQKEQLRRLKNEMENERWHLGKTIEKLQK 955
Query: 329 DENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNA 388
+ +++ +++++ L ++ E + + L E E+SR +
Sbjct: 956 EMADIVEASRTSTLE-LQNQLDEYKE---KNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011
Query: 389 SEVSVACLTERIHQMEENQHSTSEEL-QATLQELADLQQITQELNSENERLG---EEKVI 444
E+ + R +Q +++ T +L + TL++L + L + RL E+KV
Sbjct: 1012 DEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVS 1071
Query: 445 LMESLCQQ--------SDKLEHFSRQIEYFRS-LLDEHHISYVID----------EDVKS 485
+E ++ S+++ Q+E R+ LL E ++ +D+KS
Sbjct: 1072 QLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKS 1131
Query: 486 --------------GRYMELEQRYMDLAE---------------NARFEREQLLGVQQHL 516
G +++E R +L + N R ER+ V Q
Sbjct: 1132 RIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 1191
Query: 517 SNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEM 576
L + +Q ++ + + A+K + E I+ + K L LEE Q ++
Sbjct: 1192 DEHLSLTDQKDQLSLRL-KAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQL 1250
Query: 577 NRLKAQLENEKQKVAELYSIHNSGDKS-DIQDLLES-VRLDKEKAETLASSL 626
N +K L +K L + + D S D L E+ V K T+AS +
Sbjct: 1251 NSMKKDLRLKKLPSKVLDDMDDDDDLSTDGGSLYEAPVSYTFSKDSTVASQI 1302
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 93.6 bits (231), Expect = 9e-19
Identities = 170/817 (20%), Positives = 344/817 (42%), Gaps = 118/817 (14%)
Query: 169 SKSDNQISDRAALEAKVKDLLTLAKTKDVE--ILHLRNELRDMRAQLGINEDHSEGDEKS 226
++++ Q+ + +AK ++ L+K K+VE + R L+ + L + H
Sbjct: 333 AENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIG----- 387
Query: 227 EKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSE 286
+ A Q T E T+ L+ + + + E L+QL+ E L+ + +L +Q++ E
Sbjct: 388 ---MLQATQMTQ-EVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELE 443
Query: 287 K----------------LFGYQS-LSPEITPDNQSDGGGTLTSSV--EGSAPGSVEDLLS 327
K L QS L E+T N++ TL A +V
Sbjct: 444 KKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSK-TLEELAWKHHMAIEAVHSNAI 502
Query: 328 QDENTL---MDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERS-RKG 383
+D+ L ++ QH+ NL+ + +++ Q L + + L+ ++ ++ I ++ RK
Sbjct: 503 RDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKS 562
Query: 384 SSG-NASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEK 442
G ++E +A L + +++ T + L+ T L +++ EL E ++ E
Sbjct: 563 EQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEG---ELEQERQQHEETI 619
Query: 443 VILMESLCQQSDKLEHFSRQIEYFRSLLDE-----HHISYVIDEDVKSG--RYMELEQRY 495
+ E + DK+ H +I++ +L E + +ED KS + ++L+ R
Sbjct: 620 AAMKEEEKLKVDKMAH-DLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDRE 678
Query: 496 MDLAENARFER-EQLLGVQQHLSNTLKMAEQDNKEAQEMIGA--LKERSHHMERIIESEQ 552
+ A ++ ++ E LL L L++ ++ + + + A +ER + + E E+
Sbjct: 679 KNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEE 738
Query: 553 KGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKV--AELYSIHNS------GDKSD 604
+ + + E + + + E + + LEN Q+ AEL S+ ++ G + +
Sbjct: 739 QHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIE 798
Query: 605 IQDLLESVRLDKE-KAETLASSLQEDLAHTRNDA------NRLQD-AIAKVE-----DEY 651
++ L+++R + E + + + +SL+ +L H A N Q+ A AK+E D
Sbjct: 799 MEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDIS 858
Query: 652 RAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVE------------Q 699
R +E +I DL L + E + E + E I L E+E
Sbjct: 859 RRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSES 918
Query: 700 HRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAV-- 757
++ ++LH+ + LE K+L D RE + + + ++ A LQ ++
Sbjct: 919 NQQIRLHEQDLNKRLE---KELDVMTADHLREKNIMRADFNKTNELLKEINAALQVSLEE 975
Query: 758 ----VIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELE--EIKSRKQEEERGRVYN-- 809
+ + K E + I +LK L E + +KL ++ + +++ +E +V+N
Sbjct: 976 MEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVFNSS 1035
Query: 810 ----YMNAVER-----------------DLAALRQGMGLSRRSSTSSEPTPTVKTLIKSF 848
+N + + +L+AL G G+ +P P F
Sbjct: 1036 PTVGVINPLAKQKKKNDKSPTNRFVSVPNLSALESG-GVGNGHPNRLDPIPNSPVHDIEF 1094
Query: 849 DSASQVPNPAAAAIPRTPLSPSPMKTPPAAAVSPMQR 885
+S+ +P P P+T LSP+ + P A+ P ++
Sbjct: 1095 NSSKPLPQPVPPKGPKTFLSPAQSEASPVASPDPQRQ 1131
Score = 85.1 bits (209), Expect = 3e-16
Identities = 125/612 (20%), Positives = 254/612 (41%), Gaps = 90/612 (14%)
Query: 245 QLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEKLF--------GYQSLSP 296
+ Q Q +R+ + +LK E +M++D +L LD +KL Q L
Sbjct: 290 EFQGQEAILRKTIGKLKTELQMVQDEAGSL-------LDKCQKLQTALAIAENNVQVLQK 342
Query: 297 EITPDNQSDGGGTLTSS---VEGSAPGSVEDLLSQDENTLMDHQHSNSMDNLDSECSEVY 353
++ D+ +G L S VE + E L Q + ++ H + + +++
Sbjct: 343 QL--DDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGML-----QATQMT 395
Query: 354 QPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEE 413
Q +T D L++ S +E + +E R A L + ++E Q E
Sbjct: 396 QEVTIKD--LESEKSRVNERLSQLEEER------------AFLRSKTQSLDEEQKQQILE 441
Query: 414 LQATLQELADLQQ--ITQELNSENERLGEEKVILMESLCQQSDKL---EHFSRQIEYFRS 468
L+ + E QQ +EL + RL EE L E+ + ++L H + + + +
Sbjct: 442 LEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNA 501
Query: 469 LLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNK 528
+ D+ + ++E + ++L E+ +++L +++ L + L A Q+
Sbjct: 502 IRDKKKLQMDLEEQHNKDK--------LNLEEDKNQLQQELENLKEVLEDKLNTANQEIG 553
Query: 529 EAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQ 588
Q+M+ ++ E +I S Q + L L+ K ++ + + ++ +LE E+Q
Sbjct: 554 HLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQ 613
Query: 589 KVAELYSIHNSGDKSDIQDLLESVRLD-KEKAETLASSLQED--LAHTRNDANRLQDAIA 645
+ E + +K + + + + E S L+E+ L H + + + +
Sbjct: 614 QHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQ 673
Query: 646 KVEDEYRAFQEEAKKQIEDL----NMTLEKLRSDLDEKET-----------ERSDMKETI 690
+ E A ++ +K++EDL ++ + L L + +T ER + + +
Sbjct: 674 LKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQEL 733
Query: 691 FELEDEVEQ-HRAVKLHDNLIISDLENTVKKLQ-------DQKHDME-REIKTLHRRL-- 739
ELE++ +Q H+++K L +E +K Q QKH E + +K HR
Sbjct: 734 EELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESME 793
Query: 740 -----REESAEWRQFQADLQTAVVIANDIKSEAQEEIG---DLKRRLHEAQEKNEKLTKE 791
E+ + +F+ + + ++A+ ++SE + DL R H + K+ E
Sbjct: 794 GFRIEMEQELQTLRFELEDEGKAMLAS-LRSELNHQHAAAIDLLRHNHHQELAAAKMELE 852
Query: 792 LEEIKSRKQEEE 803
SR+Q +E
Sbjct: 853 RSIDISRRQSKE 864
Score = 69.3 bits (168), Expect = 2e-11
Identities = 96/484 (19%), Positives = 195/484 (40%), Gaps = 86/484 (17%)
Query: 403 MEENQHSTSEELQATLQELADLQQITQ-----------ELNSENERLGEEKVILMESLCQ 451
++ +Q T+E LQA+ ++ ADL++ Q +L +E + + +E L++ +
Sbjct: 266 LKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQK 325
Query: 452 QSDKLEHFSRQIEYFRSLLDEHHISYV--------IDEDVKSGRYMELEQRYMDLAENAR 503
L ++ + LD+ + ++ ++ + R L+Q+ DL A
Sbjct: 326 LQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAAR-ERLQQQASDLVLKAS 384
Query: 504 FEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKER------------SHHMERIIESE 551
L Q T+K E + E + L+E ++I+E E
Sbjct: 385 -HIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELE 443
Query: 552 QKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAE---------LYSIHNSG-- 600
+K A E Y+ + + Q + QL K E + ++H++
Sbjct: 444 KKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIR 503
Query: 601 DKSDIQ-DLLESVRLDKEKAETLASSLQEDLAHTR----NDANRLQDAIAKVEDEYRAFQ 655
DK +Q DL E DK E + LQ++L + + + N I ++D R +
Sbjct: 504 DKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSE 563
Query: 656 E---EAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIIS 712
+ A+ I L + E+L+++LD + + K+ + +E E+EQ R + H+ I +
Sbjct: 564 QGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQER--QQHEETIAA 621
Query: 713 DLENTVKKLQDQKHDME--------REIKTLHRRLREESAE------------------- 745
E K+ HD+E +E L LR + E
Sbjct: 622 MKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNA 681
Query: 746 ----WRQFQADLQTAV-VIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQ 800
W++ DL + ++ +++ + + L++ + ++ ++LT+ELEE++ + Q
Sbjct: 682 ARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQ 741
Query: 801 EEER 804
+ +
Sbjct: 742 QRHK 745
Score = 60.5 bits (145), Expect = 9e-09
Identities = 84/422 (19%), Positives = 169/422 (40%), Gaps = 51/422 (12%)
Query: 412 EELQATLQELADLQQITQELNSENERLG-EEKVILMESLCQQSDKL--------EHFSRQ 462
EE+Q L E + +I Q + E L K+ ++ES + K+ E + +
Sbjct: 78 EEIQQILAETRE--KILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHR 135
Query: 463 IEYFRSLLDEHHISYVI--DEDVKSGRYMELEQRYMDLAE-NARFEREQLLGVQQHLSNT 519
+E + + H+ ++ +V+ R + E++ + +FE+++ L ++
Sbjct: 136 VEDMQLCAEAQHVQRIVTMSREVEEIR-RKFEEKLRSFGQLQVQFEKDKRLALED----- 189
Query: 520 LKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRL 579
+ +E QE+ LK + H + + ++K + +E + ++E +L
Sbjct: 190 --LQAAHRREIQEL---LKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKL 244
Query: 580 KAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANR 639
E + K Y K ES++ KEK L Q A R +
Sbjct: 245 IEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGK 304
Query: 640 LQDAIAKVEDEYRAFQEEA-----------------KKQIEDLNMTLEKLRSDLDEKETE 682
L+ + V+DE + ++ +KQ++D L S E E+E
Sbjct: 305 LKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESE 364
Query: 683 RSDMKETIFELEDE-------VEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTL 735
+ +E + + + + +A ++ + I DLE+ ++ ++ +E E L
Sbjct: 365 LAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFL 424
Query: 736 HRRLREESAEWRQFQADLQTAVVIANDIKSEAQE-EIGDLKRRL-HEAQEKNEKLTKELE 793
+ + E +Q +L+ V A + E E E+ +L+ RL E + NE +K LE
Sbjct: 425 RSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLE 484
Query: 794 EI 795
E+
Sbjct: 485 EL 486
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 93.6 bits (231), Expect = 9e-19
Identities = 159/783 (20%), Positives = 316/783 (40%), Gaps = 97/783 (12%)
Query: 105 ASSTKRSTSTGNKESSSTRERLR--ERTRLNQSKKLPSAGQGANDMALAKRSRSRTATEC 162
++ T++ +T +E T++ L E R +K+ + + ND+ L +S + + +
Sbjct: 845 SAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADA 904
Query: 163 DVR---MSKSKSD-----NQISDRAALEAKVKDLLTLAKTK-DVEILHLRNELRDMRAQL 213
+ R + K+K ++++RA E ++ LT K K + E L+ ++ D+ L
Sbjct: 905 EERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTL 964
Query: 214 GINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNA 273
E E K + + ++ T+ +L ++ A++E Q ++ + +D++N
Sbjct: 965 AKVEKEKHATENKVKN--LTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
Query: 274 LGFS---LEQRLDNSE------------------KLFGYQSLSPEITPDNQSDGGGTLTS 312
L + LEQ++D+ E KL G L+ E T D ++D L
Sbjct: 1023 LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQ-QLDE 1081
Query: 313 SVEGSAPGSVEDLLSQ-DENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSES 371
+E + +L+S+ ++ ++ Q + L + E+ + + + + S
Sbjct: 1082 KLE-KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
Query: 372 EGIPSIER--SRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQ---------- 419
+ +E R +G A+ V +R + ++ + E ATLQ
Sbjct: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEE---ATLQHEAMVAALRK 1197
Query: 420 -----------ELADLQQITQELNSENERLGEEKVILM---ESLCQQSDKLEHFSRQIEY 465
++ +LQ++ Q+L E L E L E++ + LE R +E
Sbjct: 1198 KHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLED 1257
Query: 466 FRSLL---DEHHISYVIDEDVKSGRYMELEQRYMDLAEN-----ARFEREQLLGVQQHLS 517
S L +E + D + R Y + ++ R + QQ +
Sbjct: 1258 QVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQ-IE 1316
Query: 518 NTLKMAEQDNKEAQEMIGALKERSHHMERI---IESEQKGKAALAATLEEYKATVAS--D 572
E++ K + AL+ H + + E EQ+GKA L L + + VA
Sbjct: 1317 ELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRT 1376
Query: 573 QIEMNRLKA--QLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDL 630
+ E + ++ +LE K+K+A+ + ++ +E+V E LQ ++
Sbjct: 1377 KYETDAIQRTEELEEAKKKLAQRLQ--------EAEEHVEAVNAKCASLEKTKQRLQNEV 1428
Query: 631 AHTRNDANRLQDAIAKVEDEYRAFQE---EAKKQIEDLNMTLEKLRSDLDEKETERSDMK 687
D R A A ++ + R F + E K++ E+ LE + + TE +K
Sbjct: 1429 EDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVK 1488
Query: 688 ETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREESAEWR 747
E D++E R + ISDL + + Q H++E+ K + + E A
Sbjct: 1489 NVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALE 1548
Query: 748 QFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKL----TKELEEIKSRKQEEE 803
+ +A L+ I+ E + ++ R++ E E+ ++L T+ +E ++S E
Sbjct: 1549 EAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEI 1608
Query: 804 RGR 806
R R
Sbjct: 1609 RSR 1611
Score = 86.7 bits (213), Expect = 1e-16
Identities = 143/690 (20%), Positives = 279/690 (40%), Gaps = 66/690 (9%)
Query: 150 LAKRSRSRTATECDVRMSKSKSDNQISD----RAALEAKVKDLLTLAKTKDVEILHLRNE 205
L K RS +++ + + I+D RA L+ + + KD + L
Sbjct: 1248 LEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRS 1307
Query: 206 LRDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLL-----QLQEQNTAIREELNQL 260
+ Q+ + E + K++ A Q + + LL + QE ++ L++
Sbjct: 1308 KQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA 1367
Query: 261 KNENRMLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPG 320
+E + + + L+ ++K + E + + +L + +
Sbjct: 1368 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQ-RLQN 1426
Query: 321 SVEDLLSQDENT-----LMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSES---- 371
VEDL+ E + +D + N D + SE + Y+ + +A S S S
Sbjct: 1427 EVEDLMLDVERSNAACAALDKKQRN-FDKVLSEWKQKYEETQAELEASQKESRSLSTELF 1485
Query: 372 -------EGIPSIERSRKGSSGNASEVSVACLTERIHQMEENQHSTSEELQATLQELADL 424
E + +E R+ + E+S LTE+I + + H + + QE ++
Sbjct: 1486 KVKNVYEESLDQLETLRRENKNLQQEISD--LTEQIAEGGKQIHELEKIKKQVEQEKCEI 1543
Query: 425 QQITQELNSENERLGEEKVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVK 484
Q +E + E + + + L Q +++ + + L +H V E ++
Sbjct: 1544 QAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVV--ETMQ 1601
Query: 485 SGRYMELEQRYMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHM 544
S E+ R L + E + L ++ L++ ++A + + + G LKE H+
Sbjct: 1602 STLDAEIRSRNDALRVKKKMEGD-LNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHL 1660
Query: 545 ERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSD 604
+ + ++ K LA + E +A + +IE + +K+AE +
Sbjct: 1661 DDALRGQEDLKEQLA--IVERRANLLQAEIEELWATLEQTERSRKIAE----------QE 1708
Query: 605 IQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIED 664
+ D E V+L T +SL ND ++LQ + +V E R +E+AKK I D
Sbjct: 1709 LLDASERVQL----LHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITD 1764
Query: 665 LNMTLEKLRSDLDEK---ETERSDMKETIFELEDEVEQHRAVKLH-DNLIISDLENTVKK 720
M E+L+ + D E + ++++T+ +L+ +++ + L I LE V++
Sbjct: 1765 AAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRE 1824
Query: 721 LQ-----DQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLK 775
L+ +QK + E +K L + R Q + D + V+ D+ + Q ++ K
Sbjct: 1825 LEGEVENEQKRNAE-AVKGLRKHERRVKELTYQTEEDRKN-VLRLQDLVDKLQAKVKSYK 1882
Query: 776 RRLHEAQE-------KNEKLTKELEEIKSR 798
R+ EA+E K KL ELEE + R
Sbjct: 1883 RQAEEAEEQSNANLSKFRKLQHELEEAEER 1912
Score = 85.5 bits (210), Expect = 3e-16
Identities = 153/725 (21%), Positives = 295/725 (40%), Gaps = 98/725 (13%)
Query: 159 ATECDVRMSKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINED 218
AT V ++K + A + +DL + + LR + D A+LG D
Sbjct: 1159 ATSAQVELNKKRE-------AEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQID 1211
Query: 219 HSEG-DEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFS 277
+ + +K EKE TD L AI + L+ R L+D+++ L
Sbjct: 1212 NLQRVKQKLEKEKSELKMETD------DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTK 1265
Query: 278 LE--QRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGS---VEDLLSQ-DEN 331
E QRL N + + Q D L S + S S +E+L Q +E
Sbjct: 1266 EEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEE 1325
Query: 332 TLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEV 391
T + ++++ + +C D L E EG ++R+ ++ ++
Sbjct: 1326 TKAKNALAHALQSSRHDC-----------DLLREQYEEEQEGKAELQRALSKANSEVAQW 1374
Query: 392 SVACLTE---RIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMES 448
T+ R ++EE + ++ LQ + + + L +RL E LM
Sbjct: 1375 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434
Query: 449 LCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQ 508
+ + + ++ F +L E Y E+ ++ ELE + + + E +
Sbjct: 1435 VERSNAACAALDKKQRNFDKVLSEWKQKY---EETQA----ELEASQKE-SRSLSTELFK 1486
Query: 509 LLGVQQHLSNTLKMAEQDNKEAQEMIGALKERS-------HHMERIIESEQKGKAALAAT 561
+ V + + L+ ++NK Q+ I L E+ H +E+I + ++ K + A
Sbjct: 1487 VKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAA 1546
Query: 562 LEEYKATVASD-------QIEMNRLKA--------------QLENEKQKVAELYS----- 595
LEE +A++ + Q+E+N++K+ QL+ +V E
Sbjct: 1547 LEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDA 1606
Query: 596 -IHNSGD----KSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDE 650
I + D K ++ L + + A LA+ E L + RN L++ ++D
Sbjct: 1607 EIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAA---ESLRNYRNTQGILKETQLHLDDA 1663
Query: 651 YRAFQEEAKKQIEDLNMTLEKLRSDLDE-----KETERSDMKETIFELEDEVEQHRAVKL 705
R QE+ K+Q+ + L+++++E ++TERS K EL D E+ + +
Sbjct: 1664 LRG-QEDLKEQLAIVERRANLLQAEIEELWATLEQTERS-RKIAEQELLDASERVQLLHT 1721
Query: 706 HDNLIISD---LENTVKKLQDQKHDMEREIKTLHRRLREESAEWRQFQADL---QTAVVI 759
+ +I+ LEN V +LQ + ++ +E + + ++ + +L Q
Sbjct: 1722 QNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1781
Query: 760 ANDIKSEAQEEIGDLKRRLHEAQEKNEK-LTKELEEIKSRKQEEERGRVYNYMNAVERDL 818
+K ++ + DL+ RL EA++ K K+++++++R +E E G V N +
Sbjct: 1782 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELE-GEVENEQKRNAEAV 1840
Query: 819 AALRQ 823
LR+
Sbjct: 1841 KGLRK 1845
Score = 84.3 bits (207), Expect = 6e-16
Identities = 172/825 (20%), Positives = 338/825 (40%), Gaps = 146/825 (17%)
Query: 94 VENKSKISTGTASSTKRSTSTGNKESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKR 153
++NK ++ T+R+ + T ++ + ++ KK ++ LAK
Sbjct: 912 IKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK----DIDDLELTLAKV 967
Query: 154 SRSRTATECDVR---------------MSKSKSDNQ------ISDRAALEAKVKDLLTLA 192
+ + ATE V+ +SK K Q + D A E KV ++LT A
Sbjct: 968 EKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKV-NILTKA 1026
Query: 193 KTK-DVEILHLRNEL---RDMRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQE 248
KTK + ++ L L + +R L + EGD K +E+ M D+E+ QL E
Sbjct: 1027 KTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTM-----DMENDKQQLDE 1081
Query: 249 QNTAIREELN--------------QLKNENRMLKDRLNALGFSLEQRLDNSEKLFGYQS- 293
+ E++ QL+ + + L+ R+ LG +E + K +S
Sbjct: 1082 KLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSD 1141
Query: 294 LSPEITPDNQ--SDGGGTLTSSVEGSAPGSVE-DLLSQD-ENTLMDHQ---------HSN 340
LS E+ ++ + GG ++ VE + E L +D E + H+ H++
Sbjct: 1142 LSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHAD 1201
Query: 341 SMDNLDSECSE---VYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASEVSVACLT 397
SM L + V Q L L + S +I +++ GN ++ + L
Sbjct: 1202 SMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAK----GNLEKMCRS-LE 1256
Query: 398 ERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLC------- 450
+++ +++ + EE Q + +L + Q E R +EK L+ L
Sbjct: 1257 DQVSELKTKE----EEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQAST 1312
Query: 451 QQSDKLEH-----------FSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLA 499
QQ ++L+H + ++ R D Y +++ K+ L + ++A
Sbjct: 1313 QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVA 1372
Query: 500 E-------NARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIES-- 550
+ +A E+L ++ L+ L+ AE+ + +L++ ++ +E
Sbjct: 1373 QWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1432
Query: 551 --EQKGKAALAA----------TLEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHN 598
++ AA AA L E+K Q E L+A + + EL+ + N
Sbjct: 1433 LDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAE---LEASQKESRSLSTELFKVKN 1489
Query: 599 SGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDE---YRAFQ 655
++S D LE++R + + + S L E +A + L+ +VE E +A
Sbjct: 1490 VYEES--LDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAAL 1547
Query: 656 EEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLE 715
EEA+ +E + +++ +L++ +S++ I E ++E++Q +K + ++ ++
Sbjct: 1548 EEAEASLEHEEGKILRIQLELNQV---KSEVDRKIAEKDEEIDQ---LKRNHTRVVETMQ 1601
Query: 716 NTV--------------KKLQDQKHDMEREIKTLHRRLREESAEWRQFQADLQTAVVIAN 761
+T+ KK++ ++ME ++ +R E +R Q L+ + +
Sbjct: 1602 STLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLD 1661
Query: 762 DIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGR 806
D QE DLK +L + + L E+EE+ + ++ ER R
Sbjct: 1662 DAL-RGQE---DLKEQLAIVERRANLLQAEIEELWATLEQTERSR 1702
Score = 46.2 bits (108), Expect = 2e-04
Identities = 45/221 (20%), Positives = 102/221 (46%), Gaps = 15/221 (6%)
Query: 593 LYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYR 652
L S + + +++ + + + K+E L+E + + N LQ + D
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 653 AFQEEAKKQIED---LNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHRAVKLHDNL 709
+E ++ I++ L ++++ +E+E +++ +LEDE + +
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK------- 955
Query: 710 IISDLENTVKKLQDQKHDMEREIKTLHRR---LREESAEWRQFQADLQ-TAVVIANDIKS 765
I DLE T+ K++ +KH E ++K L L E A+ + + LQ T +D+++
Sbjct: 956 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015
Query: 766 EAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEERGR 806
E ++++ L + + +++ + L LE+ K + + ER +
Sbjct: 1016 E-EDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 93.2 bits (230), Expect = 1e-18
Identities = 143/765 (18%), Positives = 311/765 (40%), Gaps = 101/765 (13%)
Query: 117 KESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQIS 176
KE +R+ E T L + + +A K T+ + R+ + + Q
Sbjct: 992 KEKKLLEDRIAEFTT-----NLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 1046
Query: 177 D--RAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEG-----DEKSEKE 229
+ R LE DL +I L+ ++ +++ QL E+ + +E++ ++
Sbjct: 1047 EKTRRKLEGDSTDLSD-------QIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099
Query: 230 TIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNS---E 286
+ + ++ES + +LQE + R N+ + + R L + L AL LE LD++ +
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 287 KLFGYQSLSPEITPDNQSDGGGTLTSSVE---GSAPGSVEDLLSQDENT-LMDHQHSNSM 342
+L + I + T + ++ +VE+L Q E T + +
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
Query: 343 DNLDSE----CSEVYQPLTSSDDA------LDAPSSSESEGIPSIERSRKGSSGNASEVS 392
L++E +EV L D+ ++A ER R + +++
Sbjct: 1220 QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279
Query: 393 VAC--LTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLC 450
V +T + Q + +++ A +L D Q++ QE N +K+ L L
Sbjct: 1280 VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN-------RQKLSLSTKLK 1332
Query: 451 QQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLL 510
Q D+ F Q+E +E+ K ++ + +A+ + + E +
Sbjct: 1333 QVEDEKNSFREQLEE--------------EEEAKHNLEKQIATLHAQVADMKK-KMEDSV 1377
Query: 511 GVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVA 570
G L+ AE+ ++ Q+ + L +R + +K K L L++ +
Sbjct: 1378 G-------CLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Query: 571 SDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKE-KAETLASSLQED 629
+ L+ + + Q +AE +I S ++ +D E+ +KE KA +LA +L+E
Sbjct: 1431 HQRQSACNLEKKQKKFDQLLAEEKTI--SAKYAEERDRAEAEAREKETKALSLARALEE- 1487
Query: 630 LAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKET 689
A + + ++ ++R E+ +D+ ++ +L E + +MK
Sbjct: 1488 -------AMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQ 1540
Query: 690 IFELEDEVEQHRAVKLHDNLIIS--------DLENTVKKLQDQKHDMEREIKTLHRRLRE 741
+ ELEDE++ KL + + DL+ ++ +++K + R+++ + L +
Sbjct: 1541 LEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELED 1600
Query: 742 ESAEWRQFQA----------DLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKE 791
E + A DL+ + AN + EA +++ L+ ++ + + +
Sbjct: 1601 ERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRAS 1660
Query: 792 LEEIKSRKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSE 836
EEI ++ +E E+ + ++E ++ L++ + + R+ ++
Sbjct: 1661 REEILAQAKENEK-----KLKSMEAEMIQLQEELAAAERAKRQAQ 1700
Score = 89.0 bits (219), Expect = 2e-17
Identities = 151/758 (19%), Positives = 309/758 (40%), Gaps = 83/758 (10%)
Query: 117 KESSSTRERLRERTRLNQSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQIS 176
++ S E L E+ L Q+K++ + + A + R A E V + + K D++
Sbjct: 1192 QKHSQAVEELAEQ--LEQTKRVKANLEKAKQTL--ENERGELANEVKVLL-QGKGDSE-H 1245
Query: 177 DRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDH-----SEGDEKSEKET- 230
R +EA++++L + K E +R EL D +L + D+ S+ D KS K T
Sbjct: 1246 KRKKVEAQLQEL----QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTK 1301
Query: 231 ---IMAHQPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQRLDNSEK 287
+ Q D + L + Q ++ +L Q+++E +++L E+ N EK
Sbjct: 1302 DFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE----EEEEAKHNLEK 1357
Query: 288 LFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSN--SMDNL 345
D G L ++ E V+ L +D L + D L
Sbjct: 1358 QIATLHAQVADMKKKMEDSVGCLETAEE------VKRKLQKDLEGLSQRHEEKVAAYDKL 1411
Query: 346 DSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSSGNASE---VSVACLTER--- 399
+ + + Q L D L + + ++E+ +K +E +S ER
Sbjct: 1412 EKTKTRLQQEL----DDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRA 1467
Query: 400 ---IHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKL 456
+ E S + L+ +++ A+L+++ ++ +E E L K + +S+ +
Sbjct: 1468 EAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSK 1527
Query: 457 EHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHL 516
+Q+E ++ L+E ED K + L+ + + EQ ++ L
Sbjct: 1528 RALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQL 1587
Query: 517 SNTLKMAE---QDNKEAQEMIGALKERSH----HMERIIESEQKGKAALAATLEEYKATV 569
++ E +D ++ + M A +++ +E I+S K + L + +A +
Sbjct: 1588 VRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQM 1647
Query: 570 ASDQIEMNRLKAQLEN----EKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASS 625
E++ +A E K+ +L S+ + +Q+ L + K +A+
Sbjct: 1648 KDCMRELDDTRASREEILAQAKENEKKLKSME--AEMIQLQEELAAAERAKRQAQQERDE 1705
Query: 626 LQEDLAHTRN-------DANRLQDAIAKVEDEYRAFQ----------EEAKKQIEDLNMT 668
L +++A++ + RL+ IA++E+E Q ++A QI+ +N
Sbjct: 1706 LADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTD 1765
Query: 669 LEKLRSDLDEKETERSDMKETIFELEDEV-EQHRAVKLHDNLIISDLENTVKKLQDQKHD 727
L RS + E R ++ EL+ ++ E VK I+ LE + +L++Q +
Sbjct: 1766 LNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDN 1825
Query: 728 MEREIKTLHRRLREESAEWRQFQADLQTAVVIANDIKSEAQE---EIGDLKRRLHEAQEK 784
+E + +++R + + + A K +A + + LKR+L EA+E+
Sbjct: 1826 ETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEE 1885
Query: 785 NEKLTKELEEIKSRKQEEERGRVYNYMNAVERDLAALR 822
++ RK + E +A+ R++++L+
Sbjct: 1886 AQR-----ANASRRKLQRELEDATETADAMNREVSSLK 1918
Score = 77.0 bits (188), Expect = 9e-14
Identities = 141/645 (21%), Positives = 253/645 (39%), Gaps = 104/645 (16%)
Query: 167 SKSKSDNQISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDMRAQLGINEDHSEGDEKS 226
S SKS D +ALE++++D L + ++ + L L +L+ + + + E +E++
Sbjct: 1292 SDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEA 1351
Query: 227 ----EKETIMAH-QPTDVESTLLQLQEQNTAIREELNQLKNENRMLKDRLNALGFSLEQR 281
EK+ H Q D++ + E + E ++K R L+ L L E++
Sbjct: 1352 KHNLEKQIATLHAQVADMKKKM----EDSVGCLETAEEVK---RKLQKDLEGLSQRHEEK 1404
Query: 282 LDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDLLSQDENTLMDHQHSNS 341
+ +KL ++ + D D S+ D L +E T+ +++
Sbjct: 1405 VAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTI-SAKYAEE 1463
Query: 342 MDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRK----------------GSS 385
D ++E E S AL+ ++E +ER K G S
Sbjct: 1464 RDRAEAEAREKETKALSLARALEEAMEQKAE----LERLNKQFRTEMEDLMSSKDDVGKS 1519
Query: 386 GNASEVSVACLTERIHQMEENQHSTSEELQAT----LQELADLQ----QITQELNSENER 437
+ E S L +++ +M+ +ELQAT L+ +LQ Q ++L +E+
Sbjct: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
Query: 438 LGEEKVILMESLCQQSDKLEHFSRQIEYF---RSLLD------EHHISYVI---DEDVKS 485
E+K L+ + + +LE +Q R L+ E HI DE +K
Sbjct: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639
Query: 486 GRYMELEQR-YMDLAENARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALK------ 538
R ++ + + M ++ R RE++L + LK E + + QE + A +
Sbjct: 1640 LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1699
Query: 539 --ERSHHMERIIESEQKGKAALA---------ATLEEY----------------KATVAS 571
ER + I S KG AL A LEE KA +
Sbjct: 1700 QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759
Query: 572 DQIEMN----------------RLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLD 615
DQI + +L+ Q + K K+ E+ S K+ I L +
Sbjct: 1760 DQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819
Query: 616 KEKAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSD 675
+E+ + Q R +L+D + +V+DE R E+ K Q + + L++L+
Sbjct: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRN-AEQYKDQADKASTRLKQLKRQ 1878
Query: 676 LDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKK 720
L+E E E + +L+ E+E N +S L+N +++
Sbjct: 1879 LEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923
Score = 65.1 bits (157), Expect = 4e-10
Identities = 92/459 (20%), Positives = 188/459 (40%), Gaps = 67/459 (14%)
Query: 399 RIHQMEENQHSTSEELQATLQELADLQQITQELNSENERLGEEKVILMESLCQQSDKLEH 458
++ + EE + EEL ++ + E+ + +L EK+ L E L +++
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETE---- 894
Query: 459 FSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAENARFEREQLLGVQQHLSN 518
+ E R+ L + + ELE+ DL E E+ QHL
Sbjct: 895 LCAEAEELRARL--------------TAKKQELEEICHDLEARVEEEEERC----QHLQA 936
Query: 519 TLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNR 578
K +Q+ +E +E + E + ++ E+ A LEE + + ++ +
Sbjct: 937 EKKKMQQNIQELEEQL----EEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAK 992
Query: 579 LKAQLEN-----------EKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETL----- 622
K LE+ E++K L + N + I DL E +R ++++ + L
Sbjct: 993 EKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAM-ITDLEERLRREEKQRQELEKTRR 1051
Query: 623 -----ASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLD 677
++ L + +A + L+ +AK E+E +A +++ NM L+K+R
Sbjct: 1052 KLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIR---- 1107
Query: 678 EKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHR 737
E E++ S+++E +LE E + + +LE +L+D + + +
Sbjct: 1108 ELESQISELQE---DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 738 RLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKS 797
R +E + + + + +T +++ + + + +L +L E+ +++ LE+ K
Sbjct: 1165 REQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQL----EQTKRVKANLEKAK- 1219
Query: 798 RKQEEERGRVYNYMNAVERDLAALRQGMGLSRRSSTSSE 836
+ E ERG + N ++ L QG G S E
Sbjct: 1220 QTLENERGELAN-------EVKVLLQGKGDSEHKRKKVE 1251
Score = 65.1 bits (157), Expect = 4e-10
Identities = 133/702 (18%), Positives = 287/702 (40%), Gaps = 84/702 (11%)
Query: 150 LAKRSRSRTATECDVRMSKSKSDNQISDRAALEAKVKDLLTLAK-TKDVEILHLRNELRD 208
L + +++ A ++R S++ +++++ +VK L AK T + E L NE++
Sbjct: 1176 LEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKV 1235
Query: 209 MRAQLGINEDHSEGDEKSEKETIMAHQPTDVESTLLQLQEQNTAIREELNQ---LKNENR 265
+ G +E + E +E + + E +L ++ T ++ EL+ L +++
Sbjct: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFN--EGERVRTELADKVTKLQVELDNVTGLLSQSD 1293
Query: 266 MLKDRLNALGFSLEQRLDNSEKLFGYQSLSPEITPDNQSDGGGTLTSSVEGSAPGSVEDL 325
+L +LE +L ++++L ++ Q T VE E L
Sbjct: 1294 SKSSKLTKDFSALESQLQDTQELLQEEN--------RQKLSLSTKLKQVEDEKNSFREQL 1345
Query: 326 LSQDENTLMDHQHSNSMDNLDSECSEVYQPLTSSDDALDAPSSSESEGIPSIERSRKGSS 385
++E H + L ++ +++ + + S L+ + + +++ +G S
Sbjct: 1346 EEEEE---AKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRK----LQKDLEGLS 1398
Query: 386 GNASEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNSENER----LGEE 441
E A ++E+ + +EL L +L +Q L + ++ L EE
Sbjct: 1399 QRHEEKVAA-----YDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEE 1453
Query: 442 KVILMESLCQQSDKLEHFSRQIEYFRSLLDEHHISYVIDEDVKSGRYMELEQRYMDLAEN 501
K I + ++ D+ E +R+ E ++L ++ ++E ++ + ELE+ L +
Sbjct: 1454 KTISAK-YAEERDRAEAEAREKET-KAL----SLARALEEAME--QKAELER----LNKQ 1501
Query: 502 ARFEREQLLGVQQHLSNTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAAT 561
R E E L+ + + ++ E+ + ++ + +K + +E +++ + K L
Sbjct: 1502 FRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN 1561
Query: 562 LEEYKATVASDQIEMNRLKAQLENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAET 621
L+ KA D R + E +KQ V ++ +++ LE R + A
Sbjct: 1562 LQAMKAQFERDL--QGRDEQSEEKKKQLVRQV---------REMEAELEDERKQRSMAVA 1610
Query: 622 LASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKET 681
L+ DL +D A + D ++EA KQ+ L ++ +LD+
Sbjct: 1611 ARKKLEMDL----------KDLEAHI-DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRA 1659
Query: 682 ERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTL------ 735
R ++ E E +++ A + ++ E ++ Q ++ ++ EI
Sbjct: 1660 SREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGAL 1719
Query: 736 ----HRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLH---EAQEKNEKL 788
RRL A+ + + Q + ND +A +I + L+ +KNE
Sbjct: 1720 ALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENA 1779
Query: 789 TKELE----EIKSRKQEEE---RGRVYNYMNAVERDLAALRQ 823
++LE E+K + QE E + + + A+E +A L +
Sbjct: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821
Score = 42.0 bits (97), Expect = 0.003
Identities = 76/350 (21%), Positives = 141/350 (40%), Gaps = 70/350 (20%)
Query: 518 NTLKMAEQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQI--- 574
N++ D K+A ++ E ++ RI +S+ +A + A LEE + +D I
Sbjct: 727 NSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGF 786
Query: 575 -----EMNRLKAQLENEKQKVAELYSIHNSGDK------------SDIQDLLESVRLDKE 617
KA + ++Q A N + ++ LL+ R ++E
Sbjct: 787 QACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEE 846
Query: 618 ---KAETLASSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRS 674
K E L ++ LA N ++ +++ E QE+ + + E L E+LR+
Sbjct: 847 MMAKEEELVKVREKQLA-AENRLTEMETLQSQLMAEKLQLQEQLQAETE-LCAEAEELRA 904
Query: 675 DLDEKETERSDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKT 734
L K+ E ++E +LE VE+ E + LQ +K M++ I+
Sbjct: 905 RLTAKKQE---LEEICHDLEARVEEE--------------EERCQHLQAEKKKMQQNIQE 947
Query: 735 LHRRLREESAEWRQFQAD----------LQTAVVIAND-------IKSEAQEEIGDLKRR 777
L +L EE + ++ Q + L+ +I D K ++ I +
Sbjct: 948 LEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTN 1007
Query: 778 LHEAQEKNEKLTK----------ELEEIKSRKQEEERGRVYNYMNAVERD 817
L E +EK++ L K +LEE + R++E++R + +E D
Sbjct: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEE-RLRREEKQRQELEKTRRKLEGD 1056
Score = 30.8 bits (68), Expect = 7.5
Identities = 38/159 (23%), Positives = 67/159 (42%), Gaps = 12/159 (7%)
Query: 116 NKESSSTRERLRERTRLN-QSKKLPSAGQGANDMALAKRSRSRTATECDVRMSKSKSDNQ 174
N E S ++ R +L Q+K+L Q +K S TA E + + + DN+
Sbjct: 1767 NLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNE 1826
Query: 175 ISDRAALEAKVKDLLTLAKTKDVEILHLRNELRDM--------RAQLGINEDHSEGDEKS 226
+R A +V+ T K KDV +L + +E R+ +A + + + +E
Sbjct: 1827 TKERQAACKQVR--RTEKKLKDV-LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAE 1883
Query: 227 EKETIMAHQPTDVESTLLQLQEQNTAIREELNQLKNENR 265
E+ ++ L E A+ E++ LKN+ R
Sbjct: 1884 EEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.122 0.322
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,370,803
Number of Sequences: 37866
Number of extensions: 1803545
Number of successful extensions: 24945
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 500
Number of HSP's successfully gapped in prelim test: 1456
Number of HSP's that attempted gapping in prelim test: 11975
Number of HSP's gapped (non-prelim): 8328
length of query: 1117
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1004
effective length of database: 13,968,660
effective search space: 14024534640
effective search space used: 14024534640
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.