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Search of human proteins with 224451053
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224451053 homeobox C14 [Homo sapiens]
(188 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224451053 homeobox C14 [Homo sapiens] 398 e-111
gi|239747698 PREDICTED: similar to hCG1784039 [Homo sapiens] 55 5e-08
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 52 3e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 52 3e-07
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo... 51 7e-07
gi|118600985 zinc finger protein 91 [Homo sapiens] 50 9e-07
gi|239751420 PREDICTED: similar to hCG2039376 [Homo sapiens] 49 2e-06
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 49 3e-06
gi|148746195 trichohyalin [Homo sapiens] 48 4e-06
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 48 4e-06
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 48 6e-06
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 48 6e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 47 7e-06
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 47 7e-06
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 47 7e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 1e-05
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 47 1e-05
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 47 1e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 4e-05
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 45 5e-05
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 45 5e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 44 6e-05
gi|52426743 cisplatin resistance-associated overexpressed protei... 44 6e-05
gi|19923485 cisplatin resistance-associated overexpressed protei... 44 6e-05
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 44 8e-05
gi|118600967 shroom family member 4 [Homo sapiens] 44 1e-04
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 43 1e-04
gi|24308223 hypothetical protein LOC57577 [Homo sapiens] 43 1e-04
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 43 2e-04
gi|21361639 DIPB protein [Homo sapiens] 43 2e-04
>gi|224451053 homeobox C14 [Homo sapiens]
Length = 188
Score = 398 bits (1022), Expect = e-111
Identities = 188/188 (100%), Positives = 188/188 (100%)
Query: 1 MHRARWLTPVIPALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGK 60
MHRARWLTPVIPALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGK
Sbjct: 1 MHRARWLTPVIPALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGK 60
Query: 61 QKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAK 120
QKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAK
Sbjct: 61 QKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAK 120
Query: 121 FKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWRSLCCQG 180
FKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWRSLCCQG
Sbjct: 121 FKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWRSLCCQG 180
Query: 181 WSRTPALK 188
WSRTPALK
Sbjct: 181 WSRTPALK 188
>gi|239747698 PREDICTED: similar to hCG1784039 [Homo sapiens]
Length = 161
Score = 54.7 bits (130), Expect = 5e-08
Identities = 27/33 (81%), Positives = 27/33 (81%)
Query: 1 MHRARWLTPVIPALWEAEAGRSRGQEIETILAN 33
M RARWLTPVIPALWEAEA GQEIET LAN
Sbjct: 60 MGRARWLTPVIPALWEAEACGLXGQEIETSLAN 92
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 52.0 bits (123), Expect = 3e-07
Identities = 36/133 (27%), Positives = 71/133 (53%), Gaps = 14/133 (10%)
Query: 42 DQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQK 101
D+D E+S+ ++D ++K R+ E R+RERE+E + E+E + E+E +R+RE E+++
Sbjct: 368 DRDRERSSDR-NKDRSRSREKSRDR-ERERERERERERERERERERERERERERERERER 425
Query: 102 QYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKK---YN 158
+ +KR + + + KL R +E+ +++ W + RKK Y
Sbjct: 426 EKDKKRDREED-EEDAYERRKLERKLREKEA--------AYQERLKNWEIRERKKTREYE 476
Query: 159 KEMSKRKHKKKHM 171
KE + + +++ M
Sbjct: 477 KEAEREEERRREM 489
Score = 43.9 bits (102), Expect = 8e-05
Identities = 24/55 (43%), Positives = 39/55 (70%), Gaps = 2/55 (3%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKNEKELQD-EQENKRKRENEKQKQYPEKR 107
E+E+ K+K R+E E R RERE+E + E+E ++ E+E +R+RE EK+K+ +R
Sbjct: 292 EEEKGKKEKERQEIEKER-RERERERERERERREREREREREREREKEKERERER 345
Score = 41.2 bits (95), Expect = 5e-04
Identities = 23/92 (25%), Positives = 45/92 (48%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R R +E E +++ D+ E+ E +++ ++ + R R R
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
EK E+E + E+E +R+RE E++++ +R
Sbjct: 386 EKSRDRERERERERERERERERERERERERER 417
Score = 40.4 bits (93), Expect = 0.001
Identities = 17/54 (31%), Positives = 34/54 (62%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E E+ +++ RE +RERE+E + E+E + E+E +R+RE ++ + ++R
Sbjct: 304 EIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKER 357
Score = 40.0 bits (92), Expect = 0.001
Identities = 18/54 (33%), Positives = 32/54 (59%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E + +++ RE R+RERE+E + EKE + E+E +R R+ ++ K+ R
Sbjct: 308 ERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDR 361
Score = 40.0 bits (92), Expect = 0.001
Identities = 18/53 (33%), Positives = 31/53 (58%)
Query: 55 DEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+ + +++ RE E R+RERE+E + EKE + E+E R R+ K++ R
Sbjct: 311 ERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDR 363
Score = 38.9 bits (89), Expect = 0.003
Identities = 20/55 (36%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKN-EKELQDEQENKRKRENEKQKQYPEKR 107
E E+ +K R E E R+RERE+ E+ E+E + E+E +++RE E+++ R
Sbjct: 299 EKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDR 353
Score = 38.1 bits (87), Expect = 0.004
Identities = 16/53 (30%), Positives = 32/53 (60%)
Query: 55 DEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+ + +++ R E E R+RERE+E++ E+E + E++ R R E+ + +R
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 365
Score = 37.4 bits (85), Expect = 0.008
Identities = 16/65 (24%), Positives = 35/65 (53%)
Query: 43 QDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQ 102
Q+ E+ + + +++ E E R+REREKE++ E+E + +++ R +E ++ +
Sbjct: 303 QEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRD 362
Query: 103 YPEKR 107
R
Sbjct: 363 RERDR 367
Score = 35.4 bits (80), Expect = 0.029
Identities = 20/88 (22%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEK 80
R R +E+E ++K+ ++ ++ D Q+ +E E R+ + ++E +
Sbjct: 523 RDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPE 582
Query: 81 NEKELQDEQENKRKRENE-KQKQYPEKR 107
+E+E +++QE + KRE ++++ PE++
Sbjct: 583 SEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 33.9 bits (76), Expect = 0.085
Identities = 16/55 (29%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Query: 54 EDEQNGKQKWRE-EGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E E+ +++ RE E E R+RE+EKE + E+E +++ ++R+ ++ ++ R
Sbjct: 315 ERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR 369
Score = 33.5 bits (75), Expect = 0.11
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQD---PEQSTGNYSEDEQNGKQKWREEGEAGRK 72
EAE R +E+ K+ +D D P+ G+ + ++K E E RK
Sbjct: 478 EAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRK 537
Query: 73 REREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
RE+E+ E+ + L E E ++ +Q E+R
Sbjct: 538 REKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR 572
Score = 33.1 bits (74), Expect = 0.14
Identities = 22/98 (22%), Positives = 45/98 (45%), Gaps = 2/98 (2%)
Query: 16 EAEAGRSRG--QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKR 73
E E G+ QEIE +++ + E+ E E+ +++ E E R R
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Query: 74 EREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSK 111
+R KE +++ + +++ R+R +++ K R S+
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389
Score = 30.8 bits (68), Expect = 0.72
Identities = 14/48 (29%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Query: 60 KQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
K+ E+G+ ++R+ ++E+ E+E + E+E +R RE E++++ +R
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERER-RERERERERERER 335
Score = 30.4 bits (67), Expect = 0.94
Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 12/93 (12%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKR-- 73
E E R R +E E +K ++D E + + + ++K RE+ A ++R
Sbjct: 408 EREREREREREREREREREKDKKRDREEDEEDAY-----ERRKLERKLREKEAAYQERLK 462
Query: 74 -----EREKEEKNEKELQDEQENKRKRENEKQK 101
ER+K + EKE + E+E +R+ E ++
Sbjct: 463 NWEIRERKKTREYEKEAEREEERRREMAKEAKR 495
Score = 28.1 bits (61), Expect = 4.7
Identities = 16/87 (18%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEK 80
R R +E E +K+ +++ ++ E +++ ++ + + R +R K+
Sbjct: 323 REREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRS 382
Query: 81 NEKELQDEQENKRKRENEKQKQYPEKR 107
+E ++E R+RE E++++ +R
Sbjct: 383 RSREKSRDRE--RERERERERERERER 407
Score = 27.7 bits (60), Expect = 6.1
Identities = 12/44 (27%), Positives = 26/44 (59%)
Query: 64 REEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
RE + ++ +EEK +KE + ++ K +RE E++++ +R
Sbjct: 279 REISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERER 322
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 52.0 bits (123), Expect = 3e-07
Identities = 32/92 (34%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Query: 15 WEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRE 74
W++E R R +EIET KK+ ++ + E E K++ RE G+ +K E
Sbjct: 34 WQSEI-REREREIETRKEGKKERESERKKERREREKRKRERE---KERKRERGKKEKKGE 89
Query: 75 REKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
R+KEE+ K+ + E+ENK E EK+K+ +K
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKK 121
Score = 43.5 bits (101), Expect = 1e-04
Identities = 27/92 (29%), Positives = 50/92 (54%), Gaps = 5/92 (5%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R +E KK+ +++ E+ E +Q G+++ EE + ++ER
Sbjct: 132 ERERKEERKREERKERERKKEER---EKERERKERKKRERKQVGEKE--EERKEKERKER 186
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+K E+N KE + E+E K +RE +K+++ E+R
Sbjct: 187 KKRERNRKERKKERERKERRERKKERKKKEER 218
Score = 41.6 bits (96), Expect = 4e-04
Identities = 42/170 (24%), Positives = 71/170 (41%), Gaps = 23/170 (13%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEG-------E 68
E E R RG++ E KK+ + E+ E E+ K++ +E G E
Sbjct: 74 EKERKRERGKK-EKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE 132
Query: 69 AGRKREREKEEKNEKELQDEQENK----RKRENEKQKQYPEKRLVSKSLMHTLWAKFKLN 124
RK ER++EE+ E+E + E+ K ++R+ ++KQ EK K K + N
Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
Query: 125 RCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWR 174
R +E ++ + K +K +E K + K + WR
Sbjct: 193 RKERKKE-----------RERKERRERKKERKKKEERKKERQKDRQTNWR 231
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/144 (25%), Positives = 64/144 (44%), Gaps = 14/144 (9%)
Query: 40 PWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKR------ 93
P Q QS E E +++ ++E E+ RK+ER + EK ++E + E++ +R
Sbjct: 28 PCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKK 87
Query: 94 ----KRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQW 149
K E E++K+ EK K K R T +E + + ++ +
Sbjct: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE- 146
Query: 150 FCKTRKKYNKEMSK-RKHKKKHMR 172
+ RKK +E + RK +KK R
Sbjct: 147 --RERKKEEREKERERKERKKRER 168
Score = 36.6 bits (83), Expect = 0.013
Identities = 33/169 (19%), Positives = 74/169 (43%), Gaps = 20/169 (11%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEG--EAGRKR 73
E E+ R + + +++ ++ ++ G ++E+ K++ RE+ E K
Sbjct: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113
Query: 74 EREKEEK----------NEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKL 123
+R+K+EK E+E ++E++ + ++E E++K+ EK K + K
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK--------ERKK 165
Query: 124 NRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMR 172
+ E E + ++ + K RKK + +R+ KK+ +
Sbjct: 166 RERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Score = 34.7 bits (78), Expect = 0.050
Identities = 21/92 (22%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R ++ E +K+ + E+ + E+ K++ R+E +K +
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK-KERERKERRERKKERK 213
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+KEE+ ++ +D Q N R++E K+++ K+
Sbjct: 214 KKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
sapiens]
Length = 1198
Score = 50.8 bits (120), Expect = 7e-07
Identities = 23/29 (79%), Positives = 25/29 (86%)
Query: 9 PVIPALWEAEAGRSRGQEIETILANKKQS 37
PVIPALWE E GRS+GQEIETILAN+ S
Sbjct: 2 PVIPALWEVEMGRSQGQEIETILANRSHS 30
>gi|118600985 zinc finger protein 91 [Homo sapiens]
Length = 1191
Score = 50.4 bits (119), Expect = 9e-07
Identities = 23/27 (85%), Positives = 25/27 (92%)
Query: 7 LTPVIPALWEAEAGRSRGQEIETILAN 33
+TPVIP LWEAEAG SRGQE+ETILAN
Sbjct: 1158 ITPVIPLLWEAEAGGSRGQEMETILAN 1184
>gi|239751420 PREDICTED: similar to hCG2039376 [Homo sapiens]
Length = 858
Score = 49.3 bits (116), Expect = 2e-06
Identities = 23/27 (85%), Positives = 24/27 (88%)
Query: 7 LTPVIPALWEAEAGRSRGQEIETILAN 33
L PVIPALW+AEAGRSRGQE ET LAN
Sbjct: 666 LPPVIPALWKAEAGRSRGQEFETSLAN 692
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 48.5 bits (114), Expect = 3e-06
Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R R +E E ++ D+D ++ E ++ K++ RE E R+RER
Sbjct: 704 ERELERERAREREREREKERDRERDRDRDHDRERERERERDRE-KEREREREERERERER 762
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
E+E + E+E + E+ +R +E E+Q+ + +K
Sbjct: 763 ERERERERERERERARERDKERERQRDWEDK 793
Score = 44.3 bits (103), Expect = 6e-05
Identities = 22/93 (23%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTG-NYSEDEQNGKQKWREEGEAGRKRE 74
E + R + +E+E A +++ ++D E+ ++ + + +++ RE+ + E
Sbjct: 696 ERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREE 755
Query: 75 REKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
RE+E + E+E + E+E +R+R E+ K+ +R
Sbjct: 756 RERERERERERERERERERERARERDKERERQR 788
Score = 43.9 bits (102), Expect = 8e-05
Identities = 43/167 (25%), Positives = 76/167 (45%), Gaps = 27/167 (16%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E R R +E E +++ ++D E+ ED+ G+ RE KRE +
Sbjct: 755 ERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRRE------KREEIR 808
Query: 78 EEKNEKELQDEQENKRKRENE---KQKQYPEKRLV------------SKSLMHTLWAKFK 122
E++N ++ DE+++K++ NE +Q P++R K+ H L
Sbjct: 809 EDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRL----- 863
Query: 123 LNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKK 169
L++ QES SLS +T + +W + RK KE S+R +++
Sbjct: 864 LSQVVRPQESRSLS-PSHLTEDRQGRWKEEDRKPERKESSRRYEEQE 909
Score = 43.1 bits (100), Expect = 1e-04
Identities = 24/92 (26%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R R +E E +++ A +++ E+ + +++ ++ E E R++ER
Sbjct: 690 ERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKER 749
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E+ E+ E+E + E+E +R+RE E++++ +R
Sbjct: 750 ER-EREERERERERERERERERERERERARER 780
Score = 40.0 bits (92), Expect = 0.001
Identities = 23/91 (25%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNG---KQKWRE-EGEAGRKRERE 76
R + ++ + + + A D++ E+ E E+ ++K RE E E R+RERE
Sbjct: 659 RREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERERE 718
Query: 77 KEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+E++ ++E ++++ R+RE E+++ ++R
Sbjct: 719 REKERDRERDRDRDHDRERERERERDREKER 749
Score = 39.3 bits (90), Expect = 0.002
Identities = 19/86 (22%), Positives = 49/86 (56%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEK 80
R+R ++ E +++ ++D E+ E E+ +++ E E R+R+R+++
Sbjct: 675 RARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHD 734
Query: 81 NEKELQDEQENKRKRENEKQKQYPEK 106
E+E + E++ +++RE E++++ E+
Sbjct: 735 RERERERERDREKEREREREERERER 760
Score = 39.3 bits (90), Expect = 0.002
Identities = 24/95 (25%), Positives = 49/95 (51%), Gaps = 3/95 (3%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
+ E R R +E E ++ + + E++ E E+ ++ + + R+RER
Sbjct: 680 DRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERER 739
Query: 76 EKEEKNEKELQ---DEQENKRKRENEKQKQYPEKR 107
E+E EKE + +E+E +R+RE E++++ +R
Sbjct: 740 ERERDREKEREREREERERERERERERERERERER 774
Score = 38.9 bits (89), Expect = 0.003
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWRE-EGEAGRKRE 74
E E + R +E + + ++ ++D E+ E+ + +++ RE E E R+RE
Sbjct: 716 EREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 775
Query: 75 REKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
R +E E+E Q + E+K K ++++++ E R
Sbjct: 776 RARERDKERERQRDWEDKDKGRDDRREKREEIR 808
Score = 38.1 bits (87), Expect = 0.004
Identities = 20/89 (22%), Positives = 48/89 (53%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E R R +E E +++ D++ E+ E + +++ +E + R R+R+
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPEK 106
+ + E+E + ++E +R+RE E++++ E+
Sbjct: 734 DRERERERERDREKEREREREERERERER 762
Score = 37.0 bits (84), Expect = 0.010
Identities = 21/93 (22%), Positives = 47/93 (50%), Gaps = 1/93 (1%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E + R R +E E ++ +++ E+ E E+ ++ + + RER
Sbjct: 678 ERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRER 737
Query: 76 EKEEKNEKELQDEQE-NKRKRENEKQKQYPEKR 107
E+E + ++E + E+E +R+RE E++++ +R
Sbjct: 738 ERERERDREKEREREREERERERERERERERER 770
Score = 35.4 bits (80), Expect = 0.029
Identities = 17/67 (25%), Positives = 37/67 (55%), Gaps = 6/67 (8%)
Query: 42 DQDPEQSTGNYSEDEQNGKQKWREEGEAGR------KREREKEEKNEKELQDEQENKRKR 95
DQ P + +++ + + REE R +R RE++ + E++ + E+E +R+R
Sbjct: 638 DQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERER 697
Query: 96 ENEKQKQ 102
+ E++K+
Sbjct: 698 DREREKE 704
Score = 32.7 bits (73), Expect = 0.19
Identities = 18/70 (25%), Positives = 38/70 (54%), Gaps = 5/70 (7%)
Query: 34 KKQSAMPWDQDPEQSTGNYSED---EQNGKQKWREEGEAGRKREREKEEKNEKELQDEQE 90
+KQS P + P + G + + + + ++ R E G KR+REK+ + E+E + +Q
Sbjct: 384 RKQSP-PRHRSPMREKGRHDHERTSQSHDRRHERREDTRG-KRDREKDSREEREYEQDQS 441
Query: 91 NKRKRENEKQ 100
+ R ++++
Sbjct: 442 SSRDHRDDRE 451
Score = 31.6 bits (70), Expect = 0.42
Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E+ R R +E E I K+++ +++ E T +D NG + E + +R+K
Sbjct: 115 ESSRGRHREKEDIKITKERTPESEEENVEWETNR--DDSDNGDINYDYVHELSLEMKRQK 172
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPE 105
++ +L+ E KR+ K++ PE
Sbjct: 173 IQRELMKLEQENMEKREEIIIKKEVSPE 200
Score = 31.6 bits (70), Expect = 0.42
Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 20/120 (16%)
Query: 1 MHRARWLTPVIPALWEAEAGRSRGQEIETILANKK-------QSAMPW-DQDPEQSTGNY 52
M R+R P +P E + SRG +I++ +N +S+ P D+ PE+
Sbjct: 560 MGRSRGRVPELP---EKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERD---- 612
Query: 53 SEDEQNGKQKWREEGEAGRKREREKEEKNEKELQ-----DEQENKRKRENEKQKQYPEKR 107
+ D+ R GE R+ RE++++ ++ DE E +RE + + ++R
Sbjct: 613 NRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRR 672
Score = 29.6 bits (65), Expect = 1.6
Identities = 23/105 (21%), Positives = 51/105 (48%), Gaps = 10/105 (9%)
Query: 11 IPALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAG 70
I L E RS + + ++ + + P + D + + + S D ++ Q+ R+ E
Sbjct: 1251 IDQLKRGEPSRSTSSDRQDSRSHSSRRSSP-ESDRQVHSRSGSFDSRDRLQE-RDRYEHD 1308
Query: 71 RKREREKEEKNEKELQDE--------QENKRKRENEKQKQYPEKR 107
R+RERE+ + ++E + ++ R RE E++++ ++R
Sbjct: 1309 RERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRR 1353
Score = 28.5 bits (62), Expect = 3.6
Identities = 23/106 (21%), Positives = 51/106 (48%), Gaps = 9/106 (8%)
Query: 42 DQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEK--ELQDEQEN------KR 93
+++ E+ E +++ + W + R RERE+E + +K +L E+E +R
Sbjct: 1310 ERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVER 1369
Query: 94 KRENEKQKQYPEKRLVS-KSLMHTLWAKFKLNRCPTIQESLSLSFE 138
R+ ++ + + ++ S K L + + + T ++SL+L E
Sbjct: 1370 DRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKE 1415
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.1 bits (113), Expect = 4e-06
Identities = 39/160 (24%), Positives = 79/160 (49%), Gaps = 12/160 (7%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKE 84
QE E +L ++++ Q+ E+ E +Q +Q REE E R++ERE++ + E+E
Sbjct: 1058 QEEEQLLGEERETRRR--QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 85 LQDE------QENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQ----ESLS 134
LQ E +E +++R E ++QY E+ V + L + + R ++ E
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175
Query: 135 LSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWR 174
L E + ++ + + R++ +E + + +K+ R+R
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Score = 47.4 bits (111), Expect = 7e-06
Identities = 36/161 (22%), Positives = 81/161 (50%), Gaps = 7/161 (4%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRE--R 75
E R R +E + +++ + Q+ E+ ++E+ +Q+ RE+ E R+++ R
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERRE---QQEERREQQERREQQEERREQQLRR 341
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSL 135
E+EE+ E++L+ EQE +R+ + +++Q E+R L + +L R ++ L
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 136 SFEFDMTHKQ--ISQWFCKTRKKYNKEMSKRKHKKKHMRWR 174
E + +Q + + ++ +E + +H++KH + R
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Score = 44.7 bits (104), Expect = 5e-05
Identities = 24/80 (30%), Positives = 50/80 (62%), Gaps = 7/80 (8%)
Query: 28 ETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQD 87
ET+L +++ +++P++ E+EQ K + +E +RER++EE+ ++ L+
Sbjct: 250 ETVLRKEEEKLQ--EEEPQRQRELQEEEEQLRKLERQE-----LRRERQEEEQQQQRLRR 302
Query: 88 EQENKRKRENEKQKQYPEKR 107
EQ+ +RK+E E+++Q E+R
Sbjct: 303 EQQLRRKQEEERREQQEERR 322
Score = 44.7 bits (104), Expect = 5e-05
Identities = 43/172 (25%), Positives = 86/172 (50%), Gaps = 22/172 (12%)
Query: 3 RARWLTPVIPALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQK 62
R R P L E + R +E + ++Q +P +++ EQ E E+ + +
Sbjct: 779 RGRQRLSARPPLREQRERQLRAEERQ----QREQRFLPEEEEKEQRRRQRREREK--ELQ 832
Query: 63 WREEGEAGRKREREKEEKNEKE-LQDEQENKRKRENEKQK----QYPEKRLVSKSLMHTL 117
+ EE E ++RER ++ + E++ LQ++QE +R +E + + Q E+R K HTL
Sbjct: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER---KRRRHTL 889
Query: 118 WAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKK 169
+AK P +QE L E + ++ + + R+K ++ +R+++++
Sbjct: 890 YAK------PALQEQLRK--EQQLLQEEEEELQREEREKRRRQEQERQYREE 933
Score = 44.3 bits (103), Expect = 6e-05
Identities = 37/150 (24%), Positives = 68/150 (45%), Gaps = 8/150 (5%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKE 84
QE E +L +++ Q+ E+ + +Q +Q EE E R++EREK+ + E+E
Sbjct: 938 QEEEQLLREEREKRRR--QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995
Query: 85 LQDEQENKRKRENEK------QKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFE 138
LQ E+E + E EK ++QY +K + + L + + R + E
Sbjct: 996 LQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEE 1055
Query: 139 FDMTHKQISQWFCKTRKKYNKEMSKRKHKK 168
+Q+ +TR++ E RK ++
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Score = 43.1 bits (100), Expect = 1e-04
Identities = 29/132 (21%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Query: 43 QDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQEN------KRKRE 96
Q+ E+ E +Q +Q REE E R++E E++ + + ELQ E+E +++R
Sbjct: 984 QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL 1043
Query: 97 NEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKK 156
E+++QY E+ + + L + + R ++ E +Q+ + + R++
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103
Query: 157 YNKEMSKRKHKK 168
+E R+ ++
Sbjct: 1104 QERERQCREEEE 1115
Score = 42.0 bits (97), Expect = 3e-04
Identities = 21/70 (30%), Positives = 42/70 (60%), Gaps = 6/70 (8%)
Query: 43 QDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQEN------KRKRE 96
Q+ E+ + +Q +Q REE E R++ERE++ + +K+LQ ++E +++R
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Query: 97 NEKQKQYPEK 106
E++K+Y E+
Sbjct: 984 QEREKKYREE 993
Score = 41.6 bits (96), Expect = 4e-04
Identities = 25/83 (30%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKE 84
QE E +L +++ Q+ E+ E +Q +Q EE E R++E E++ + E+E
Sbjct: 1028 QEEEQLLREEREKRRL--QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 85 LQDEQENKRKRENEKQKQYPEKR 107
LQ E+E + E EK+++ +R
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERER 1108
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/120 (20%), Positives = 63/120 (52%), Gaps = 9/120 (7%)
Query: 56 EQNGKQKWREEGEAGRKREREKEEKNEKELQDE------QENKRKRENEKQKQYPEKRLV 109
++ ++ REE E R++E+E++ + E++LQ E +E +++R E+++QY + + +
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 110 SKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKK 169
+ L + + R ++ E +Q+ + + R+K ++ +R+++KK
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR---EEREKRRRQEWERQYRKK 1023
Score = 37.0 bits (84), Expect = 0.010
Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 26/113 (23%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWR----EEGEAGRKR 73
+ G+ R QE E +++S + W Q+ E++ E+EQ W+ E+ E GR+R
Sbjct: 726 QEGQRRRQEQEE-KRRRRESELQW-QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
Query: 74 ---------EREK----EEKNEKEL-------QDEQENKRKRENEKQKQYPEK 106
+RE+ EE+ ++E + EQ +++RE EK+ Q+ E+
Sbjct: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE 836
Score = 37.0 bits (84), Expect = 0.010
Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 13/98 (13%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQD---PEQSTGNYSEDEQN-----GKQKWREEG 67
E E + R QE + ++Q ++ P+Q G Y +E+ +Q+ R+E
Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER 1841
Query: 68 EAGRKRE-----REKEEKNEKELQDEQENKRKRENEKQ 100
+ + E +EK + E+EL E+E KR++E E++
Sbjct: 1842 DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879
Score = 36.6 bits (83), Expect = 0.013
Identities = 31/148 (20%), Positives = 73/148 (49%), Gaps = 5/148 (3%)
Query: 28 ETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQD 87
E L +++ W + E++ + E E+ +Q R++ E R+R + EE+ +E Q+
Sbjct: 444 EQRLKREQEERRDWLKREEETERH--EQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Query: 88 EQENKRKRENEKQKQYPEKRLVSKS-LMHTLWAKFKLNRCPTIQESLSLSFEFD--MTHK 144
+E + +RE E++++ KR + L L ++ +L R + L E + + +
Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561
Query: 145 QISQWFCKTRKKYNKEMSKRKHKKKHMR 172
+ Q + +++ ++ KR+ +++ R
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQR 589
Score = 36.6 bits (83), Expect = 0.013
Identities = 19/89 (21%), Positives = 47/89 (52%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E + R QE+E ++Q +Q+ + Y + + + + E + R++ER++
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPEK 106
+ + E++L+ E+E ++ R E +++ E+
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREE 1800
Score = 36.2 bits (82), Expect = 0.017
Identities = 26/131 (19%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
Query: 46 EQSTGNYSEDEQNGKQKWREEGEAGRKRE--REKEEKNEKELQDEQENKRKRENEKQKQY 103
EQ + E+ +Q+ R E + R++E RE++ + E+E + ++ R+ + E++++
Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQ 375
Query: 104 PEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSK 163
+R L + +L R ++ L E + +Q + + R++ +E +
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Query: 164 RKHKKKHMRWR 174
+KH+++ R
Sbjct: 436 QKHEQERREQR 446
Score = 35.8 bits (81), Expect = 0.022
Identities = 18/106 (16%), Positives = 53/106 (50%)
Query: 64 REEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKL 123
++EG+ R+ + EK + E ELQ ++E + R+ ++++Q + ++ + + +L
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784
Query: 124 NRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKK 169
+ P ++E + ++ ++ + +K + +R+ +K+
Sbjct: 785 SARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830
Score = 35.8 bits (81), Expect = 0.022
Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKE 84
QE E +L + + Q+ E+ E +Q +Q REE E R++ERE++ + E+E
Sbjct: 1148 QEEEQLLREEPEKRRR--QELERQYREEEELQQEEEQLLREEQEK-RRQERERQYREEEE 1204
Query: 85 LQDEQENKRKRENEKQ 100
LQ ++ +R R+ +++
Sbjct: 1205 LQRQKRKQRYRDEDQR 1220
Score = 35.8 bits (81), Expect = 0.022
Identities = 28/154 (18%), Positives = 74/154 (48%), Gaps = 14/154 (9%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEK 80
R Q+++ +L +++ ++ Q + +E+ Q REE + ++R+R+ +E+
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEE---QLEREEQKEAKRRDRKSQEE 1317
Query: 81 NEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFD 140
+ ++ +E +R++E +++ + E+ L + + L R QE E +
Sbjct: 1318 KQLLREEREEKRRRQETDRKFREEEQLLQERE-------EQPLRR----QERDRKFREEE 1366
Query: 141 MTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWR 174
+ H++ + F + ++ ++ +RK K+ + R
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Score = 35.0 bits (79), Expect = 0.038
Identities = 23/94 (24%), Positives = 47/94 (50%), Gaps = 5/94 (5%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKR-E 74
+ E R R Q+ + ++Q +++ ++ Q KQ REE E R+R E
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQ----LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Query: 75 REKEEKNEKELQDEQENKRKRENEKQKQYPEKRL 108
+++ + E++L E+E + R E+ +++ E+ L
Sbjct: 1334 TDRKFREEEQLLQEREEQPLRRQERDRKFREEEL 1367
Score = 35.0 bits (79), Expect = 0.038
Identities = 22/73 (30%), Positives = 44/73 (60%), Gaps = 13/73 (17%)
Query: 52 YSEDEQNGKQ----KWREEGEAGRKRERE---KEEKNEKELQDEQENKRK------RENE 98
+ E+EQ +Q K+REE + ++RE + ++E++ K L++EQ+ +R+ RE E
Sbjct: 1448 FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507
Query: 99 KQKQYPEKRLVSK 111
+ Q PE++ + +
Sbjct: 1508 LRSQEPERKFLEE 1520
Score = 34.3 bits (77), Expect = 0.065
Identities = 23/93 (24%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E R + QE E L + +S ++ E+ + E+ +K E+ ++ +R
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE---EKRLEQERREQRLKR 569
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKRL 108
E+EE+ ++ L+ E+E +++R +Q++ E+RL
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Score = 34.3 bits (77), Expect = 0.065
Identities = 21/95 (22%), Positives = 50/95 (52%), Gaps = 6/95 (6%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E + R + + E +L +++ + +Q+ + ++E+ + REE ++ +R
Sbjct: 535 EQQLRREQEERREQLLKREEEKRL--EQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Query: 76 EKEEKNEKELQDEQ----ENKRKRENEKQKQYPEK 106
E+EE+ E+ L+ E+ E + +RE +++ PE+
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627
Score = 34.3 bits (77), Expect = 0.065
Identities = 28/162 (17%), Positives = 69/162 (42%), Gaps = 21/162 (12%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNY----SEDEQNGKQKWREEGEAGR----K 72
R + +E+E + +++ ++PE+ E E+ +Q+ R E + R K
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 73 REREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQES 132
RE E+E ++ ++ +E +R++E +++Q + + + W +
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQL-------ESEAD 713
Query: 133 LSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWR 174
S + KQ Q ++ ++ KR+ ++ ++W+
Sbjct: 714 ARQSKVYSRPRKQEGQ------RRRQEQEEKRRRRESELQWQ 749
Score = 33.9 bits (76), Expect = 0.085
Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 35/113 (30%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER----- 75
R R Q+++ +++ + DQ+ +S EQ QKWR + E RKR R
Sbjct: 843 RERAQQLQ-----EEEDGLQEDQERRRS------QEQRRDQKWRWQLEEERKRRRHTLYA 891
Query: 76 -------------------EKEEKNEKELQDEQENKRKRENEKQKQYPEKRLV 109
E+ ++ E+E + QE +R+ E+Q Q E++L+
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Score = 33.9 bits (76), Expect = 0.085
Identities = 18/83 (21%), Positives = 44/83 (53%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKE 84
+E + + +++ + D+D + Q +K+REE + R++ERE++ E++
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 85 LQDEQENKRKRENEKQKQYPEKR 107
++ +++ RE E+ Q E++
Sbjct: 1454 QLRQERHRKFREEEQLLQEREEQ 1476
Score = 33.9 bits (76), Expect = 0.085
Identities = 15/61 (24%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Query: 46 EQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPE 105
++ + EDEQ Q R+EG+ ++ER+++ + +++L E+E ++ E+ +++ E
Sbjct: 1591 QEQERKFMEDEQ---QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 106 K 106
+
Sbjct: 1648 E 1648
Score = 33.5 bits (75), Expect = 0.11
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E + R QE E L + + ++ Q Q +K+REE + R++ERE+
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 78 EEKNEKELQDEQENKRK-RENEKQKQYPEK 106
+ E++ QE +RK RE E+ +Q E+
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQLRQETEQ 1737
Score = 33.1 bits (74), Expect = 0.14
Identities = 23/87 (26%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEK 80
R +G+E + ++Q + Q+ E+ E +++ +E E R+RE ++EE+
Sbjct: 219 RRKGREEKQQQRRERQDRV--FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
Query: 81 NEKELQDEQENKRKRENEKQKQYPEKR 107
++L + QE +R+R+ E+Q+Q +R
Sbjct: 277 QLRKL-ERQELRRERQEEEQQQQRLRR 302
Score = 32.7 bits (73), Expect = 0.19
Identities = 21/88 (23%), Positives = 47/88 (53%), Gaps = 5/88 (5%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E R+R E++L +++Q ++D + + E+ Q+ R++ + + E
Sbjct: 97 EEKRARCDGKESLLQDRRQ-----EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEG 151
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPE 105
EE++EK+ + EQ ++++R+ E +Q E
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQE 179
Score = 32.7 bits (73), Expect = 0.19
Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Query: 54 EDEQNGKQKWREEGEAGR---KREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E + +Q+ R E E R K E+E+ E+ K Q+E+ + KRE E ++ E+R
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Score = 32.7 bits (73), Expect = 0.19
Identities = 14/51 (27%), Positives = 31/51 (60%)
Query: 57 QNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
Q +K+REE + ++RE ++ E + + +E + ++E E+Q+ P++R
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Score = 32.0 bits (71), Expect = 0.32
Identities = 16/54 (29%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 54 EDEQNGKQKWREEGEAGR----KREREKEEKNEKELQDEQENKRKRENEKQKQY 103
E + +Q+ R E + R +RE+E+E +K Q+ +E + KRE E+++ +
Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Score = 31.6 bits (70), Expect = 0.42
Identities = 29/173 (16%), Positives = 72/173 (41%), Gaps = 17/173 (9%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E G+ R Q+ + +++ A +Q +Q + ++ ++ WR+ E + ER
Sbjct: 130 EEEPGQRRRQKRQE---QERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREER 186
Query: 76 EKEEK--------NEKELQDEQENKR------KRENEKQKQYPEKRLVSKSLMHTLWAKF 121
EE+ +E DE++ +R +R+ ++KQ + + ++
Sbjct: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEW 246
Query: 122 KLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWR 174
+ +E L E +++ + + RK +E+ + + +++ + R
Sbjct: 247 RKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR 299
Score = 31.6 bits (70), Expect = 0.42
Identities = 17/64 (26%), Positives = 36/64 (56%), Gaps = 7/64 (10%)
Query: 46 EQSTGNYSEDEQNGKQKWREEGEAGRKRERE-------KEEKNEKELQDEQENKRKRENE 98
EQ E+E++ ++ +E E KRE+E +EE+ E+ Q+ ++ + KR+ E
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 99 KQKQ 102
++++
Sbjct: 482 EERR 485
Score = 31.2 bits (69), Expect = 0.55
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 5/96 (5%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQ----DPEQSTGNYSEDEQNGKQKWREEGEA 69
L E + R QE+E +++ +Q +PE+ E + +++ ++E E
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Query: 70 GRKREREKEEKNEKELQDEQENKRKRENEKQKQYPE 105
+ E+EK + E+E Q +E + +R+ KQ+ E
Sbjct: 1183 LLREEQEK-RRQERERQYREEEELQRQKRKQRYRDE 1217
Score = 31.2 bits (69), Expect = 0.55
Identities = 19/89 (21%), Positives = 45/89 (50%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E GR +E + + +++ ++ + + Q+ +K+REE + ++ER++
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPEK 106
+ + E++ QE +RK E+Q+ E+
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQER 1459
Score = 30.8 bits (68), Expect = 0.72
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 8/101 (7%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWRE-------- 65
L E E + R QE + ++Q +++ + Q ++K+RE
Sbjct: 1676 LQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQET 1735
Query: 66 EGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
E E R++ER ++ E++L+ E+E ++ R E+ +++ E+
Sbjct: 1736 EQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776
Score = 30.4 bits (67), Expect = 0.94
Identities = 19/79 (24%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKR-EREKEEKNEK 83
+E + + +++ + +Q+ + E+E+ ++ RE+ E +R +RE+ E+ E+
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 84 ELQDEQENKRKRENEKQKQ 102
E + EQ KR+ E+++Q
Sbjct: 613 EERREQRLKREEPEEERRQ 631
Score = 30.4 bits (67), Expect = 0.94
Identities = 12/49 (24%), Positives = 31/49 (63%)
Query: 57 QNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPE 105
Q+ +K+REE + ++RE ++ + E++ + E ++ R E+++++ E
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME 1599
Score = 30.0 bits (66), Expect = 1.2
Identities = 19/85 (22%), Positives = 42/85 (49%)
Query: 23 RGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNE 82
R QE + L ++ D+ Q Q +K+ EE R++ERE++ +++
Sbjct: 1605 RRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHD 1664
Query: 83 KELQDEQENKRKRENEKQKQYPEKR 107
++ + +E + +E E+Q+ ++R
Sbjct: 1665 RDRKFREEEQLLQEGEEQQLRRQER 1689
Score = 29.6 bits (65), Expect = 1.6
Identities = 16/70 (22%), Positives = 42/70 (60%), Gaps = 8/70 (11%)
Query: 43 QDPEQSTGNYSEDEQN-----GKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKREN 97
Q+PE+ + E+EQ ++K+ +E + R++ER ++ + +++ + +E + ++E
Sbjct: 1511 QEPERK---FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567
Query: 98 EKQKQYPEKR 107
E+Q+ ++R
Sbjct: 1568 EEQQLSRQER 1577
Score = 29.6 bits (65), Expect = 1.6
Identities = 22/91 (24%), Positives = 50/91 (54%), Gaps = 6/91 (6%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E + R QE + ++Q + +++ +Q S+ + +++ R+E E + R +
Sbjct: 1758 EREEQQLRRQERDRKFREEEQ--LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ 1815
Query: 76 EKEEK---NEKELQDEQENKRKRENEKQKQY 103
+++ K E++LQ E++ +R R+ E+ +QY
Sbjct: 1816 QRDGKYRWEEEQLQLEEQEQRLRQ-ERDRQY 1845
Score = 29.3 bits (64), Expect = 2.1
Identities = 17/53 (32%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 56 EQNGKQKWREEGEAGRKREREKEEKNEKELQDEQ-ENKRKRENEKQKQYPEKR 107
EQ K++ E + KRE E+ ++ K Q+E+ E + KRE ++ + E+R
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Score = 29.3 bits (64), Expect = 2.1
Identities = 11/47 (23%), Positives = 30/47 (63%)
Query: 57 QNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQY 103
Q +Q R+E R+++R+++ + E++L+ E+E ++ E+ +++
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKF 1581
Score = 28.9 bits (63), Expect = 2.7
Identities = 24/103 (23%), Positives = 55/103 (53%), Gaps = 8/103 (7%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDP---EQSTGNYSEDE---QNGKQKWREEG 67
L E + R QE + ++Q ++ P ++ + E+E Q +K+ EE
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 68 EAGRKREREKEE-KNEKELQ-DEQENKRKRENEKQKQYPEKRL 108
+ R++ERE++ K E++L+ E+E + +++ +++ + E++L
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQL 1423
Score = 28.1 bits (61), Expect = 4.7
Identities = 22/119 (18%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 54 EDEQNGKQKWREEGEAGR----KREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLV 109
E + +Q+ R E + R +RE++ + E+E +++ + +RE +++ E+R
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR-- 455
Query: 110 SKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKK 168
W K + QE + D ++ +W K ++ +E +R+ ++
Sbjct: 456 -------DWLKREEETERHEQERRKQQLKRDQEEERRERWL-KLEEEERREQQERREQQ 506
Score = 27.7 bits (60), Expect = 6.1
Identities = 30/136 (22%), Positives = 62/136 (45%), Gaps = 17/136 (12%)
Query: 52 YSEDEQNGKQKWRE-------------EGEAGRKREREKEEKNEKELQDEQENKRK-REN 97
+ E+EQ +++ RE E E +++R+++ + E++ QE RK RE
Sbjct: 1376 FLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREE 1435
Query: 98 EKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQ-ISQWFCKTRKK 156
E+Q + E+ K L + + +R +E L E H+Q + F + ++
Sbjct: 1436 EQQVRRQERE--RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
Query: 157 YNKEMSKRKHKKKHMR 172
++ RK +++ +R
Sbjct: 1494 LRRQERDRKFREQELR 1509
Score = 27.7 bits (60), Expect = 6.1
Identities = 17/83 (20%), Positives = 39/83 (46%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKE 84
QE + + ++ D+D + E+ +Q R+E + + E +K + E+E
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 85 LQDEQENKRKRENEKQKQYPEKR 107
+ ++ ++ R E Q+Q ++R
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQER 1617
Score = 27.7 bits (60), Expect = 6.1
Identities = 19/90 (21%), Positives = 46/90 (51%), Gaps = 12/90 (13%)
Query: 20 GRSRGQEIETILANKKQSAMPWDQD----PEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
G+ R +E E + +++ + ++D E+ + + ++ W+EE + KR +
Sbjct: 1819 GKYRWEE-EQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ---KRRQ 1874
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPE 105
E+E K L++E ++++E ++ +Q E
Sbjct: 1875 ERERK----LREEHIRRQQKEEQRHRQVGE 1900
Score = 27.3 bits (59), Expect = 7.9
Identities = 16/86 (18%), Positives = 43/86 (50%), Gaps = 12/86 (13%)
Query: 35 KQSAMPWDQDPEQSTGN-----YSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQ 89
++S + W +PE+ Y + +N + + E+ + R+R+ ++ + L ++Q
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQL---RDRQSQQDLQHLLGEQQ 1275
Query: 90 ENKRKRE----NEKQKQYPEKRLVSK 111
E R++E ++ + +PE+ + +
Sbjct: 1276 ERDREQERRRWQQRDRHFPEEEQLER 1301
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 48.1 bits (113), Expect = 4e-06
Identities = 33/115 (28%), Positives = 57/115 (49%), Gaps = 18/115 (15%)
Query: 55 DEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLM 114
DE+ G + + E R+REREKE + EKEL+ EQE +R++E EK ++ +++ K L
Sbjct: 489 DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEK--EKEL- 545
Query: 115 HTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKK 169
++ E + KQ + + +K+ KE+ K K ++K
Sbjct: 546 ---------------EKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEK 585
Score = 47.8 bits (112), Expect = 6e-06
Identities = 24/93 (25%), Positives = 54/93 (58%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R R +E+E +++ D++ +Q E EQ +++ +E + +++E
Sbjct: 508 EREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKEL 567
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKRL 108
E++++ EKELQ +E +++ E EK+++ E+++
Sbjct: 568 ERQKEKEKELQKMKEQEKECELEKEREKLEEKI 600
Score = 45.1 bits (105), Expect = 4e-05
Identities = 33/137 (24%), Positives = 68/137 (49%), Gaps = 13/137 (9%)
Query: 42 DQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQK 101
+++ E+ E E+ +Q+ +E E R+R++EKE++ EKE + ++E +++R+ EK+K
Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565
Query: 102 QYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFD--------MTHKQISQWFCKT 153
+ ++ K L K + C +E L + + M KQ S+ C
Sbjct: 566 ELERQKEKEKELQK---MKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNK 622
Query: 154 RKK--YNKEMSKRKHKK 168
++ + ++ S R K+
Sbjct: 623 EEEPVFTRQDSNRSEKE 639
Score = 43.9 bits (102), Expect = 8e-05
Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 5/80 (6%)
Query: 33 NKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK----EEKNEKELQDE 88
++K + PE+ E E+ +++ +E E R++EREK +++ EKEL+ E
Sbjct: 489 DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKE 548
Query: 89 QENKRKRENEKQKQYPEKRL 108
QE +R+ E E+ KQ EK L
Sbjct: 549 QEKQREMEKER-KQEKEKEL 567
Score = 41.6 bits (96), Expect = 4e-04
Identities = 20/68 (29%), Positives = 41/68 (60%)
Query: 44 DPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQY 103
+ + S E E+ +++ +E E +++EREKE + ++E Q E+E + ++E EKQ++
Sbjct: 496 EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM 555
Query: 104 PEKRLVSK 111
++R K
Sbjct: 556 EKERKQEK 563
Score = 39.7 bits (91), Expect = 0.002
Identities = 20/78 (25%), Positives = 44/78 (56%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKE 84
+E E +++ + +Q+ E+ + E+ +++ E E ++RE EKE K EKE
Sbjct: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKE 564
Query: 85 LQDEQENKRKRENEKQKQ 102
+ E++ ++++E +K K+
Sbjct: 565 KELERQKEKEKELQKMKE 582
Score = 38.9 bits (89), Expect = 0.003
Identities = 19/75 (25%), Positives = 43/75 (57%)
Query: 28 ETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQD 87
E I +++ +++ E+ E E+ ++ ++E E ++E+EK+ + EKE +
Sbjct: 502 EEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561
Query: 88 EQENKRKRENEKQKQ 102
E+E + +R+ EK+K+
Sbjct: 562 EKEKELERQKEKEKE 576
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 47.8 bits (112), Expect = 6e-06
Identities = 40/157 (25%), Positives = 70/157 (44%), Gaps = 24/157 (15%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEG---EAGRK 72
+ E R R +E ET ++Q ++ ++ T D+ +++ RE E RK
Sbjct: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDR-ERDKDRDRERKRETDRNRERNRK 117
Query: 73 REREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQES 132
RE++++ E+E E+E +R+RE E+Q+Q KR + WA
Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR--WA------------- 162
Query: 133 LSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKK 169
E + K+ + K RK+ KE +R+ KK+
Sbjct: 163 -----EREERKKERKKERKKERKEKKKEEKRREDKKR 194
Score = 39.3 bits (90), Expect = 0.002
Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R R +E +T N+ + +D + ++ E+ +++ + + R+RE
Sbjct: 18 ERERDRQRERENQTERENRHRQ-----RDRHRERDRQTDREKERERQKERDRQRQRERET 72
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E+E + ++E Q ++E KR+ + E+ K +R
Sbjct: 73 ERETERQRERQRQRERKRQTDRERDKDRDRER 104
Score = 38.9 bits (89), Expect = 0.003
Identities = 21/83 (25%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKW--REEGEAGRKRER 75
+ GR R ++ E +++ +++ ++ E ++ +Q+W REE + RK+ER
Sbjct: 117 KGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRE-RQRWAEREERKKERKKER 175
Query: 76 EKEEKNEKELQDEQENKRKRENE 98
+KE K +K+ + +E+K+++ E
Sbjct: 176 KKERKEKKKEEKRREDKKRKWGE 198
Score = 33.9 bits (76), Expect = 0.085
Identities = 16/49 (32%), Positives = 30/49 (61%), Gaps = 5/49 (10%)
Query: 64 REEGEAGRKREREKEEKNEKELQDEQENK-----RKRENEKQKQYPEKR 107
+ E + G++ ERE++ + E+E Q E+EN+ R RE ++Q ++R
Sbjct: 8 KRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKER 56
Score = 33.9 bits (76), Expect = 0.085
Identities = 21/90 (23%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E R+R + + KQ+ D++ E+ E ++ ++K + E R ERE+
Sbjct: 107 ETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREE 166
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+K E++ + ++E K K++ EK+++ +++
Sbjct: 167 RKK-ERKKERKKERKEKKKEEKRREDKKRK 195
Score = 32.3 bits (72), Expect = 0.25
Identities = 12/32 (37%), Positives = 24/32 (75%)
Query: 71 RKREREKEEKNEKELQDEQENKRKRENEKQKQ 102
R+RER++E KE + E++ +R+REN+ +++
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERE 34
Score = 30.8 bits (68), Expect = 0.72
Identities = 13/35 (37%), Positives = 24/35 (68%)
Query: 68 EAGRKREREKEEKNEKELQDEQENKRKRENEKQKQ 102
E R+ +R KE + E++ Q E+EN+ +REN +++
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQR 40
Score = 27.7 bits (60), Expect = 6.1
Identities = 10/31 (32%), Positives = 21/31 (67%)
Query: 72 KREREKEEKNEKELQDEQENKRKRENEKQKQ 102
+R+RE++ + ++ + E+E R+RE E Q +
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTE 32
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 47.8 bits (112), Expect = 6e-06
Identities = 27/93 (29%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWRE-EGEAGRKRE 74
E +A R R E ET +++ D+D ++ +Q+ E + E RKRE
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 75 REKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
R++E + E+E ++E +R+RE E+++Q +R
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETER 335
Score = 47.4 bits (111), Expect = 7e-06
Identities = 24/80 (30%), Positives = 44/80 (55%)
Query: 23 RGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNE 82
R +E E K+Q D++ E+ E E+ ++ + E E R+RERE++ + E
Sbjct: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETE 334
Query: 83 KELQDEQENKRKRENEKQKQ 102
++ + E+E KRKR+ E ++
Sbjct: 335 RDREKERERKRKRQTEMDRE 354
Score = 42.4 bits (98), Expect = 2e-04
Identities = 19/66 (28%), Positives = 36/66 (54%)
Query: 42 DQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQK 101
D D + N ++ + ++K + E E RKRER +E+ ++ +E +R RE E+++
Sbjct: 48 DADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERER 107
Query: 102 QYPEKR 107
Q +R
Sbjct: 108 QTDRER 113
Score = 42.4 bits (98), Expect = 2e-04
Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSE-DEQNGKQKWREEGEAGRKRE 74
E E R R ++ E +Q+ + E+ E D Q+ +++ E + R R+
Sbjct: 338 EKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQ 397
Query: 75 REKEEKNEKELQDEQENKRKRENEKQKQ 102
+E+E + EK+ ++E +++RE EK ++
Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRE 425
Score = 40.8 bits (94), Expect = 7e-04
Identities = 25/91 (27%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRK--- 72
E E R R +E E ++Q D++ E+ + E + +++ R+ G GR+
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD-RERNRQTGREGRRQAE 368
Query: 73 REREKE-EKNEKELQDEQENKRKRENEKQKQ 102
RERE+E E++ + ++ +E +R R+ ++QK+
Sbjct: 369 RERERERERDRQSAREREERERDRDRDRQKE 399
Score = 40.8 bits (94), Expect = 7e-04
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWRE---EGEAGRK 72
+ E R G+E +++ D+ + D +QK RE E + +
Sbjct: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQ 411
Query: 73 REREKEEKNEKELQDEQENKRKRENEKQK 101
RE EK+ + EK+ + E+ +R RE EKQK
Sbjct: 412 RETEKQREREKDRESERGRERGREREKQK 440
Score = 40.4 bits (93), Expect = 0.001
Identities = 24/96 (25%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPE-----QSTGNYSEDEQNGKQKWREEGEAG 70
E + R R ++ E +K+ +++ E Q+ G + Q +K RE +
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER-QTD 164
Query: 71 RKREREKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
R+R+R+ E +KE + E+ + +RE E+Q++ K
Sbjct: 165 RERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Score = 40.0 bits (92), Expect = 0.001
Identities = 20/92 (21%), Positives = 45/92 (48%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E + R R + E +K+ D++ ++ ++ +++ EGE GR R+
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+ + + E++ E+E +R+ + E+Q+Q R
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNR 175
Score = 39.7 bits (91), Expect = 0.002
Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 11/103 (10%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSED-----------EQNGKQKWR 64
+AE R+ +E E +++ D+D Q D E K++ +
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQ 304
Query: 65 EEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E E R+R R++E + E+E + E++ + +R+ EK+++ KR
Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
Score = 39.7 bits (91), Expect = 0.002
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 13/101 (12%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSE---------DEQNGKQKWREE 66
E + R +E E K+Q+ M D++ + TG + + +Q RE
Sbjct: 328 ERQRETERDREKERERKRKRQTEM--DRERNRQTGREGRRQAERERERERERDRQSARER 385
Query: 67 GEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E R+R+R+++ + E+E Q E++ +RE EKQ++ + R
Sbjct: 386 EE--RERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424
Score = 38.9 bits (89), Expect = 0.003
Identities = 20/91 (21%), Positives = 46/91 (50%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R + +E ET ++ D E+ +E E+ + + + R R++
Sbjct: 118 EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQK 177
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
E+E + ++ + E+E +R++EN+ + ++ E+
Sbjct: 178 EREREKNRQERRERERQREKENKTEDRHSER 208
Score = 38.9 bits (89), Expect = 0.003
Identities = 37/174 (21%), Positives = 74/174 (42%), Gaps = 15/174 (8%)
Query: 16 EAEAGRSR---GQ-EIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGR 71
E E GR R GQ E E +K+ D++ ++ T + E+ ++ +E E R
Sbjct: 134 EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Query: 72 KRERE-----------KEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAK 120
+RE+E +E + E+E + E E KR+ + E+ +Q +R K ++
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 121 FKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWR 174
+ R + + D K+ + + R++ + + + K++ R R
Sbjct: 254 RETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRER 307
Score = 38.5 bits (88), Expect = 0.003
Identities = 15/50 (30%), Positives = 34/50 (68%)
Query: 53 SEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQ 102
+E E + K++ R E + RKR+R +E + ++E + E++ R+R+ +++K+
Sbjct: 71 TERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKE 120
Score = 38.1 bits (87), Expect = 0.004
Identities = 25/95 (26%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Query: 16 EAEAGRSRGQEIETILANKKQSA-MPWDQDPEQSTGNYSEDEQNGKQKWRE--EGEAGRK 72
+AE R R +E + A +++ D+D ++ +E +++G+++ + E E R+
Sbjct: 366 QAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
Query: 73 REREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
ER +E E+E Q +E R+R+ ++Q KR
Sbjct: 426 SERGRERGREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 37.7 bits (86), Expect = 0.006
Identities = 20/88 (22%), Positives = 47/88 (53%), Gaps = 1/88 (1%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E RG++ +T +++ +++ E+ T + + ++ E E R+ R
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 76 EKEEKNEKELQ-DEQENKRKRENEKQKQ 102
E+E + EKE + +++ ++R RE E++++
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERE 217
Score = 37.4 bits (85), Expect = 0.008
Identities = 20/89 (22%), Positives = 47/89 (52%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E R R +E E +++ +++ ++ T E E+ K+K + E + R R+ +
Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPEK 106
E + + E + E+E +R R++ ++++ E+
Sbjct: 362 EGRRQAERERERERERDRQSAREREERER 390
Score = 37.0 bits (84), Expect = 0.010
Identities = 19/92 (20%), Positives = 45/92 (48%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E + R R + E +++ +++ E+ E E+ +++ + E R RE+
Sbjct: 280 ERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E+E K +++ + ++E R+ E ++Q +R
Sbjct: 340 ERERKRKRQTEMDRERNRQTGREGRRQAERER 371
Score = 36.6 bits (83), Expect = 0.013
Identities = 23/87 (26%), Positives = 47/87 (54%), Gaps = 5/87 (5%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEK 80
R+R +E E K+Q+ D+ E+ E +++ K+ E + R++ERE++
Sbjct: 56 RNRQKERER-RREKRQTERETDRKRERRR----EKDRHRKRDRHRERQRDREKERERQTD 110
Query: 81 NEKELQDEQENKRKRENEKQKQYPEKR 107
E++ Q E+E R++E E++ + +R
Sbjct: 111 RERDRQREKERNRQKERERETEREGER 137
Score = 36.6 bits (83), Expect = 0.013
Identities = 21/95 (22%), Positives = 46/95 (48%), Gaps = 3/95 (3%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R R ++ + ++Q +++ + + E+N +++ E +RER
Sbjct: 132 EREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRER 191
Query: 76 EKEEKNEKELQD---EQENKRKRENEKQKQYPEKR 107
E++ + E + +D E+ +R+RE E + + KR
Sbjct: 192 ERQREKENKTEDRHSERGRERERERETETETERKR 226
Score = 35.8 bits (81), Expect = 0.022
Identities = 18/91 (19%), Positives = 46/91 (50%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E + R R +E E K++ +++ E+ + E+ ++K + + E R+R R
Sbjct: 298 ERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNR 357
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
+ + ++ + E+E +R+R+ + ++ E+
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREER 388
Score = 35.4 bits (80), Expect = 0.029
Identities = 21/94 (22%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPE-QSTGNYSEDEQNGKQKWRE-EGEAGRKR 73
+ E R R + E +K+ +++ E + G D Q Q+ RE + +A ++R
Sbjct: 100 DREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKER 159
Query: 74 EREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
ER+ + + +++ + ++ +R+RE +Q++ +R
Sbjct: 160 ERQTDRERQRQTERNRQKEREREKNRQERRERER 193
Score = 35.4 bits (80), Expect = 0.029
Identities = 22/99 (22%), Positives = 48/99 (48%), Gaps = 14/99 (14%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
+ + R R E + K++ +++ E++ E E+ +++ + E E R++ER
Sbjct: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
Query: 76 EKEEKNEKEL--------------QDEQENKRKRENEKQ 100
E++ K + E+ Q E+E +R+RE ++Q
Sbjct: 342 ERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQ 380
Score = 35.0 bits (79), Expect = 0.038
Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSE---DEQNGKQKWREEGEAGRK 72
E E R R + E K+ +D E+ ++ D Q K++ R++ E R+
Sbjct: 72 ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK-ERERE 130
Query: 73 REREKEEKNEKELQDEQENKRKRENEKQKQ 102
ERE E +++ ++E +R+R+ EK+++
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERE 160
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 47.4 bits (111), Expect = 7e-06
Identities = 43/181 (23%), Positives = 78/181 (43%), Gaps = 25/181 (13%)
Query: 14 LWEAEAGRSRGQEI-ETILANKKQSAMPWDQDP--EQSTGNYSEDEQNGKQKWREEGEAG 70
+W E R + ++ E + Q WDQ+ E+ T + + ++K REE
Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE--- 589
Query: 71 RKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLM----HTLWAK------ 120
R REREK+ + E+E+ EQE K + + EK ++ EK + M +W +
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE 649
Query: 121 -----FKLNRCPTIQESL----SLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHM 171
++ R P +E L + + M ++ W + +K +E K+ ++ M
Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKM 709
Query: 172 R 172
R
Sbjct: 710 R 710
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 1 MHRARWLTPVIPA-LWEAEAGRSRGQEIETILANKKQSAMPWDQDP---EQSTGNYSEDE 56
+ RA++L P + + E R + E +KQ W Q+ EQ ++E
Sbjct: 255 LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEE 314
Query: 57 QNGKQKWREEGEAGRKREREKEEKNEKELQD------EQENKRKRENEKQKQYPEK 106
+ +Q+ R + RE+EKE + +KEL++ EQE K + EK ++ EK
Sbjct: 315 KMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370
Score = 37.7 bits (86), Expect = 0.006
Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 10/90 (11%)
Query: 41 WDQDPEQSTGNYSEDEQNGKQKWREEG--EAGRKREREKEEKNEKELQDEQENKRKRENE 98
W+Q E+ EQ K + +EE E R REREK+ + E+E EQE K +++ E
Sbjct: 420 WEQ-VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 478
Query: 99 -----KQKQYPEKRLVSKSLMHTLWAKFKL 123
++K++ ++RL + LW + K+
Sbjct: 479 NMWEQEEKEWQQQRLPEQK--EKLWEQEKM 506
Score = 37.4 bits (85), Expect = 0.008
Identities = 39/167 (23%), Positives = 78/167 (46%), Gaps = 30/167 (17%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKR 73
LWE E + QE E + ++Q W+Q+ + + ++ K+ W +E + R
Sbjct: 667 LWEHE----KMQEQEKM---QEQEEKIWEQEKMEK-----KTQEQEKKTWDQE----KMR 710
Query: 74 EREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLM----HTLWAK----FKLNR 125
E E + EK++++E+E R++E EK ++ EK + M +W + ++ R
Sbjct: 711 EEESMREREKKMREEEEMMREQE-EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769
Query: 126 CPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMR 172
P +E L +E + +Q W + +K + K + +++ MR
Sbjct: 770 LPEQKEKL---WEHEKMQEQEKIW--EQEEKMRDQEEKMRGQEEKMR 811
Score = 35.8 bits (81), Expect = 0.022
Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 20/104 (19%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPE--QSTGNYSEDEQNGKQ--KWREEG-- 67
LWE E + R QE + + Q W+QD + E E+ +Q K REE
Sbjct: 378 LWEQEK-QMREQEQKM----RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432
Query: 68 EAGRKREREKEEK---------NEKELQDEQENKRKRENEKQKQ 102
+ K+ R++EEK EK++++E+E R++E + QKQ
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 476
Score = 33.5 bits (75), Expect = 0.11
Identities = 21/95 (22%), Positives = 41/95 (43%), Gaps = 8/95 (8%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQN--GKQKWREEGEAGR 71
+WE E Q + +Q W+ + Q E E+ ++K ++ +
Sbjct: 647 MWEQEEKMWEQQRLP------EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Query: 72 KREREKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
K+ ++E+ E+E E+E K + E E ++ EK
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQEEK 735
Score = 33.1 bits (74), Expect = 0.14
Identities = 30/155 (19%), Positives = 69/155 (44%), Gaps = 13/155 (8%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKR 73
+WE E + R QE + +Q W+Q+ + +Q ++ W ++ K
Sbjct: 357 MWEQEE-KMREQEEKMW----RQEERLWEQEKQMREQEQKMRDQE-ERMWEQDERLREKE 410
Query: 74 EREKE-EKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQES 132
ER +E EK ++++ +E K+ +E EK+ + E+++ + + K + +E
Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMR------EEEE 464
Query: 133 LSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHK 167
E M ++ + W + ++ + + ++K K
Sbjct: 465 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499
Score = 32.3 bits (72), Expect = 0.25
Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 16/102 (15%)
Query: 14 LWEAEAG------RSRGQEIETILANKK---QSAMPWDQDPE---QSTGNYSEDE----Q 57
+WE E + RGQE + +K Q W Q+ + Q + ++E Q
Sbjct: 789 IWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQ 848
Query: 58 NGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEK 99
K + + +G+ + RE+E++ + ++E EQE K + + EK
Sbjct: 849 EEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 31.6 bits (70), Expect = 0.42
Identities = 30/158 (18%), Positives = 67/158 (42%), Gaps = 11/158 (6%)
Query: 14 LWEAEAGRSRGQEIETILANK--KQSAMPWDQD--PEQSTGNYSEDEQNGKQKWREEGEA 69
+WE E +E K +Q W+Q PEQ + ++ ++K +E+ E
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 70 GRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTI 129
++E+ +++ E+E + + ++ RE E ++ +K + +M K +
Sbjct: 686 IWEQEKMEKKTQEQE-KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ------E 738
Query: 130 QESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHK 167
QE E +M ++ W + + + + ++K K
Sbjct: 739 QEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Score = 31.2 bits (69), Expect = 0.55
Identities = 20/108 (18%), Positives = 52/108 (48%), Gaps = 9/108 (8%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKR 73
LWE E + + ++I + W Q+ + ++++ Q W +E + +
Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED--QMWEQEEKMRDQE 557
Query: 74 ER--EKEEKNEKELQDEQ-----ENKRKRENEKQKQYPEKRLVSKSLM 114
++ ++EE+ EK+ Q+++ + ++ RE E+ ++ +K + +M
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605
Score = 30.0 bits (66), Expect = 1.2
Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 10/92 (10%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER--EKEEKN- 81
+++E + KK ++ E + ++K REE E R++E +K+E+N
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 82 ----EKELQDEQENKRKR---ENEKQKQYPEK 106
EKE Q ++ ++K E EK ++ EK
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Score = 29.6 bits (65), Expect = 1.6
Identities = 16/96 (16%), Positives = 52/96 (54%), Gaps = 15/96 (15%)
Query: 34 KKQSAMPWDQD---PEQSTGNYSEDEQNGKQK---WREE---------GEAGRKREREKE 78
++Q W+Q+ EQ + ++E+ +Q+ W ++ E + +E+EK
Sbjct: 620 QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679
Query: 79 EKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLM 114
++ E+++ ++++ ++K + +++K + ++++ + M
Sbjct: 680 QEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Score = 28.9 bits (63), Expect = 2.7
Identities = 39/151 (25%), Positives = 63/151 (41%), Gaps = 14/151 (9%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKN-EK 83
QE E I +K+ + EQ ++E +Q EE E ++R E++EK E+
Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ---EEKEWQQQRLPEQKEKLWEQ 503
Query: 84 ELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTH 143
E EQE K + EK + E K +W + K+ QE E M
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKK----MWRQEKMRE----QEDQMWEQEEKMRD 555
Query: 144 KQISQWFCKTR--KKYNKEMSKRKHKKKHMR 172
++ W + R KK ++ K +++ MR
Sbjct: 556 QEQKMWDQEERMEKKTQEQEKKTWDQEEKMR 586
Score = 27.7 bits (60), Expect = 6.1
Identities = 23/99 (23%), Positives = 45/99 (45%), Gaps = 7/99 (7%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKR 73
+WE E + Q + +Q W+Q+ Q EQ K + +EE K+
Sbjct: 480 MWEQEEKEWQQQRLP------EQKEKLWEQEKMQEQEEKIW-EQEEKIRDQEEMWGQEKK 532
Query: 74 EREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKS 112
+E+ E+E Q ++ ++ R+ E++ E+R+ K+
Sbjct: 533 MWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT 571
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 47.4 bits (111), Expect = 7e-06
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 10/94 (10%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E R + +E E +K+ D+D E+ +D + K+K RE R+RE+E
Sbjct: 392 EKDREKEREREKEREKEKERGKNKDRDKERE-----KDREKDKEKDRE-----REREKEH 441
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPEKRLVSK 111
E+ +KE + EQ+ +++RE ++ K+ EKR K
Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475
Score = 40.4 bits (93), Expect = 0.001
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Query: 34 KKQSAMPWDQDPEQSTGNYSEDE-QNGKQKWREEGEAGRKREREKEEKNEKELQDEQENK 92
+K+ D++ E+ E E + GK K R++ E + RE++KE+ E+E + E E
Sbjct: 386 EKERVKEKDREKEREREKEREKEKERGKNKDRDK-EREKDREKDKEKDREREREKEHEKD 444
Query: 93 RKRENEKQKQYPEKRLVSKS 112
R +E EK++ ++R +S
Sbjct: 445 RDKEKEKEQDKEKEREKDRS 464
Score = 40.0 bits (92), Expect = 0.001
Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 34 KKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKR 93
+K + +D + T ++++ K+K RE+ E R++EREKE++ K ++E ++
Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREK-EREREKEREKEKERGKNKDRDKEREK 423
Query: 94 KRENEKQKQYPEKR 107
RE +K+K +R
Sbjct: 424 DREKDKEKDRERER 437
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/75 (24%), Positives = 40/75 (53%)
Query: 33 NKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENK 92
++++S P + + S + + K ++ E +++ER KE+ EKE + E+E +
Sbjct: 347 DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 406
Query: 93 RKRENEKQKQYPEKR 107
+++E K K ++R
Sbjct: 407 KEKERGKNKDRDKER 421
Score = 32.3 bits (72), Expect = 0.25
Identities = 25/108 (23%), Positives = 46/108 (42%), Gaps = 6/108 (5%)
Query: 1 MHRARWLTPVIPALWEAEAGRS---RGQEIETILANKKQSAMPWDQDPEQSTGNY---SE 54
M R R I A E E+G+S +G + +K +S+ ++S + S
Sbjct: 279 MKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSH 338
Query: 55 DEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQ 102
+ +QK R ++ K+ + E+ + + +KRK EK K+
Sbjct: 339 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 386
Score = 31.6 bits (70), Expect = 0.42
Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 16/125 (12%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E + RG+ + K+ ++D E+ E E + +E E +++ER
Sbjct: 404 EREKEKERGKNKD----RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459
Query: 76 EKE---EKNEKELQDEQE---------NKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKL 123
EK+ E +EK +D++ ++R R + ++++ R S+S + K K
Sbjct: 460 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 519
Query: 124 NRCPT 128
+R P+
Sbjct: 520 SRSPS 524
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 47.4 bits (111), Expect = 7e-06
Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 10/94 (10%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E R + +E E +K+ D+D E+ +D + K+K RE R+RE+E
Sbjct: 276 EKDREKEREREKEREKEKERGKNKDRDKERE-----KDREKDKEKDRE-----REREKEH 325
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPEKRLVSK 111
E+ +KE + EQ+ +++RE ++ K+ EKR K
Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359
Score = 40.4 bits (93), Expect = 0.001
Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Query: 34 KKQSAMPWDQDPEQSTGNYSEDE-QNGKQKWREEGEAGRKREREKEEKNEKELQDEQENK 92
+K+ D++ E+ E E + GK K R++ E + RE++KE+ E+E + E E
Sbjct: 270 EKERVKEKDREKEREREKEREKEKERGKNKDRDK-EREKDREKDKEKDREREREKEHEKD 328
Query: 93 RKRENEKQKQYPEKRLVSKS 112
R +E EK++ ++R +S
Sbjct: 329 RDKEKEKEQDKEKEREKDRS 348
Score = 40.0 bits (92), Expect = 0.001
Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 34 KKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKR 93
+K + +D + T ++++ K+K RE+ E R++EREKE++ K ++E ++
Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREK-EREREKEREKEKERGKNKDRDKEREK 307
Query: 94 KRENEKQKQYPEKR 107
RE +K+K +R
Sbjct: 308 DREKDKEKDRERER 321
Score = 37.4 bits (85), Expect = 0.008
Identities = 18/75 (24%), Positives = 40/75 (53%)
Query: 33 NKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENK 92
++++S P + + S + + K ++ E +++ER KE+ EKE + E+E +
Sbjct: 231 DRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 290
Query: 93 RKRENEKQKQYPEKR 107
+++E K K ++R
Sbjct: 291 KEKERGKNKDRDKER 305
Score = 32.3 bits (72), Expect = 0.25
Identities = 25/108 (23%), Positives = 46/108 (42%), Gaps = 6/108 (5%)
Query: 1 MHRARWLTPVIPALWEAEAGRS---RGQEIETILANKKQSAMPWDQDPEQSTGNY---SE 54
M R R I A E E+G+S +G + +K +S+ ++S + S
Sbjct: 163 MKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSH 222
Query: 55 DEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQ 102
+ +QK R ++ K+ + E+ + + +KRK EK K+
Sbjct: 223 NRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKE 270
Score = 31.6 bits (70), Expect = 0.42
Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 16/125 (12%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E + RG+ + K+ ++D E+ E E + +E E +++ER
Sbjct: 288 EREKEKERGKNKD----RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 343
Query: 76 EKE---EKNEKELQDEQE---------NKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKL 123
EK+ E +EK +D++ ++R R + ++++ R S+S + K K
Sbjct: 344 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 403
Query: 124 NRCPT 128
+R P+
Sbjct: 404 SRSPS 408
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 47.0 bits (110), Expect = 1e-05
Identities = 44/165 (26%), Positives = 83/165 (50%), Gaps = 18/165 (10%)
Query: 16 EAEAGRSRGQEIETILAN-KKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRE 74
E E+ +E+E++L +KQ ++ +++ E+ E+E+ +++ REE E
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQESLSSEEEEERE-----EEEEREEEEVREEEE----ER 2269
Query: 75 REKEEKNEKELQDEQENKRKRENEKQK---QYPEKRLVSKSLMHTLWAKFKLNRCPTIQE 131
+E+EE EK+++ E+E K+K++ EK+K Q E+ K + + L+ +E
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329
Query: 132 SLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWRSL 176
S SL E D K+I K K++ + +RK + R S+
Sbjct: 2330 SCSLEEEVD-REKEI----LKKEKQFKLQEQRRKSLRGRERVLSI 2369
Score = 33.1 bits (74), Expect = 0.14
Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 7/101 (6%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQ-NGKQKWREEGEAGRKRERE 76
+AG E E + +KK W Q E + S+++Q +++ E E R+ E +
Sbjct: 1498 QAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEK 1557
Query: 77 KEEKNEKELQDEQENK-----RKREN-EKQKQYPEKRLVSK 111
+++ E++ ++E+K RKR EK++ E++L +
Sbjct: 1558 EQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE 1598
Score = 31.6 bits (70), Expect = 0.42
Identities = 35/157 (22%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 25 QEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKE 84
QE + ++ + S W + ++ + E ++ K W+EE E +E EK + ++
Sbjct: 1444 QEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKA-WKEEWEKRLLQEEEKLHQAGEK 1502
Query: 85 LQDEQE---NKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFE--- 138
L E+E +K + E+ KQ E L SKS ++K T++E +S E
Sbjct: 1503 LSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQ----QYKDEEEVTLEEEVSREGEEKE 1558
Query: 139 ----FDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHM 171
+ H Q + + +K + KR +++ +
Sbjct: 1559 QQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKL 1595
Score = 27.7 bits (60), Expect = 6.1
Identities = 14/54 (25%), Positives = 30/54 (55%)
Query: 55 DEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRL 108
+EQ Q+ + RKR R ++++ ++E + QE ++ + E+Q E++L
Sbjct: 1563 EEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKL 1616
Score = 27.3 bits (59), Expect = 7.9
Identities = 24/116 (20%), Positives = 50/116 (43%), Gaps = 8/116 (6%)
Query: 62 KWREEGEAGRKREREKEEKNEKELQDEQENKRKRE----NEKQKQYPEKRLVSKSLMHTL 117
K + G+AG K+ +K + K+ ++ + E ++ + ++ +++
Sbjct: 1080 KGQRRGQAGVKKHSQKWLRGLKKTKERDSKQMSTEPGLLEDESGTEAAPIEMEEASVYSQ 1139
Query: 118 WAK----FKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKK 169
W+ KL++ QE +T K++ + K KK + K+KHKKK
Sbjct: 1140 WSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKK 1195
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 46.6 bits (109), Expect = 1e-05
Identities = 29/93 (31%), Positives = 51/93 (54%), Gaps = 5/93 (5%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWRE-EGEAGRKRE 74
E E R R ++ E +K+ ++D E+ T D + KQK RE E + GR+RE
Sbjct: 89 EKERDRDRKRDRER---RRKEKETNRNRDREKQT-EIERDREREKQKGRERERDRGRERE 144
Query: 75 REKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
R+++ + E+E Q E++ +RE E +++ +R
Sbjct: 145 RDRDREKERERQTEKDRDGQRETETERERDRER 177
Score = 46.6 bits (109), Expect = 1e-05
Identities = 23/91 (25%), Positives = 50/91 (54%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R R ++ +T ++Q+ D+ + T E ++ G+++ E R R+R
Sbjct: 182 ERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDR 241
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
KE E++ ++E++ +RK+E +K+++ +K
Sbjct: 242 GKERDRERDRKEERKKERKKERKKERKEKKK 272
Score = 44.7 bits (104), Expect = 5e-05
Identities = 24/92 (26%), Positives = 49/92 (53%), Gaps = 8/92 (8%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R+R +E KQ+ + D++ E+ G E ++ +++ + E R+R+
Sbjct: 106 EKETNRNRDRE--------KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQT 157
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
EK+ ++E + E+E R+RE +K+++ R
Sbjct: 158 EKDRDGQRETETERERDREREKQKERETERDR 189
Score = 44.7 bits (104), Expect = 5e-05
Identities = 22/85 (25%), Positives = 49/85 (57%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E R RG+E E +K+ ++D + +E E++ +++ ++E E R R+R++
Sbjct: 134 ERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR 193
Query: 78 EEKNEKELQDEQENKRKRENEKQKQ 102
+ + E+E Q ++E R+R+ + ++Q
Sbjct: 194 DTEKERERQTDRERDRQRKTQTERQ 218
Score = 43.9 bits (102), Expect = 8e-05
Identities = 35/159 (22%), Positives = 74/159 (46%), Gaps = 7/159 (4%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
+ E + +G+E E +++ D+D E+ +E +++G+++ E E R+RE+
Sbjct: 124 DREREKQKGRERERDRGRERER----DRDREKERERQTEKDRDGQRETETERERDREREK 179
Query: 76 EKEEKNE--KELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESL 133
+KE + E ++ Q + E +R+R+ ++++ K + + + +R Q
Sbjct: 180 QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239
Query: 134 SLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMR 172
E D + + K RKK K+ K K K++ R
Sbjct: 240 DRGKERD-RERDRKEERKKERKKERKKERKEKKKEEKRR 277
Score = 39.7 bits (91), Expect = 0.002
Identities = 26/90 (28%), Positives = 54/90 (60%), Gaps = 10/90 (11%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSE---DEQNGKQKWRE-EGEAGR 71
E + R R ++ +T ++++ D++ E+ T E D GK++ RE + + R
Sbjct: 200 ERQTDRERDRQRKTQTERQRET----DREGERETDRRRERQRDRDRGKERDRERDRKEER 255
Query: 72 KREREKEEKNEKELQDEQENKRKRENEKQK 101
K+ER+KE K KE +++++ +++RE++K+K
Sbjct: 256 KKERKKERK--KERKEKKKEEKRREDKKRK 283
Score = 38.9 bits (89), Expect = 0.003
Identities = 17/66 (25%), Positives = 38/66 (57%)
Query: 42 DQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQK 101
D+ E++ D + +++ R+E E R R+REK+ + E++ + E++ R+RE ++ +
Sbjct: 82 DRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGR 141
Query: 102 QYPEKR 107
+ R
Sbjct: 142 ERERDR 147
Score = 33.5 bits (75), Expect = 0.11
Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 3/54 (5%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+D Q + + RE+ E R R+R+++ + ++ E+E R R+ EKQ + R
Sbjct: 75 DDRQRERDRVREKTEKERDRDRKRDRERRRK---EKETNRNRDREKQTEIERDR 125
Score = 32.0 bits (71), Expect = 0.32
Identities = 15/64 (23%), Positives = 30/64 (46%)
Query: 44 DPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQY 103
D ++ E + + + R+ R++E+E ++E Q E E R+RE +K ++
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
Query: 104 PEKR 107
R
Sbjct: 136 ERDR 139
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 46.6 bits (109), Expect = 1e-05
Identities = 29/104 (27%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
Query: 13 ALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRK 72
AL + AG + E ILA K++ A + EQ E ++ +++ + + E R
Sbjct: 386 ALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERL 445
Query: 73 REREKEEKNEKELQDEQENKRKRENEKQKQYPE--KRLVSKSLM 114
R E+ K E+E + ++E K+K+E E++++ E KR + L+
Sbjct: 446 RLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELL 489
Score = 35.8 bits (81), Expect = 0.022
Identities = 18/54 (33%), Positives = 33/54 (61%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
++E+ KQ+ E+ +AG + +R+ EE+ + + EQE + K EKQK+ E +
Sbjct: 461 QEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETK 514
Score = 30.0 bits (66), Expect = 1.2
Identities = 17/73 (23%), Positives = 37/73 (50%)
Query: 28 ETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQD 87
+ IL +K++ + +++ E+ E Q QK E +++ RE+EE+ E ++
Sbjct: 74 QQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRR 133
Query: 88 EQENKRKRENEKQ 100
E ++ E +K+
Sbjct: 134 SLERTQQLELKKK 146
Score = 27.7 bits (60), Expect = 6.1
Identities = 14/37 (37%), Positives = 23/37 (62%)
Query: 71 RKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+KR R + EK +E + E +R+RE++K+ EKR
Sbjct: 80 QKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKR 116
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.1 bits (105), Expect = 4e-05
Identities = 39/169 (23%), Positives = 76/169 (44%), Gaps = 23/169 (13%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEG---EAG 70
+WE + R R +E E + KK W Q+ + +++++ K+ W +E E
Sbjct: 509 MWEQDE-RLREKE-ERMREQKKM----WQQEEKMREEKKTQEQE--KKTWDQEEKMREEE 560
Query: 71 RKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLM-----------HTLWA 119
R REREK+ + E+E+ EQE K + + EK ++ EK + M +W
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE 620
Query: 120 KFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKK 168
+ + ++ QE + E M ++ W + + + +E + + +K
Sbjct: 621 QEEEDKMQE-QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Score = 41.6 bits (96), Expect = 4e-04
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 17/118 (14%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEG---EAG 70
LWE E + R QE + + Q W+QD EQ ++ W +E E
Sbjct: 340 LWEQEK-QMREQEQKM----RDQEERMWEQDERLREKEERMREQ--EKMWEQEEKMQEEE 392
Query: 71 RKREREKEEKNEKELQDEQENKRKRENE-----KQKQYPEKRLVSKSLMHTLWAKFKL 123
R REREK+ + E+E EQE K +++ E ++K++ ++RL + LW + K+
Sbjct: 393 RIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK--EKLWEQEKM 448
Score = 38.5 bits (88), Expect = 0.003
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 1 MHRARWLTPVIPA-LWEAEAGRSRGQEIETILANKKQSAMPWDQDP---EQSTGNYSEDE 56
+ RA++L P + + E R + E +KQ W Q+ EQ ++E
Sbjct: 217 LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEE 276
Query: 57 QNGKQKWREEGEAGRKREREKEEKNEKELQD------EQENKRKRENEKQKQYPEK 106
+ +Q+ R + RE+EKE + +K+L++ EQE K + EK ++ EK
Sbjct: 277 KMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Score = 38.5 bits (88), Expect = 0.003
Identities = 25/103 (24%), Positives = 50/103 (48%), Gaps = 13/103 (12%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDP----------EQSTGNYSEDEQNGKQKW 63
+WE E +E + + ++Q M W+Q+ EQ ++E+ +Q+
Sbjct: 611 MWEQEEKMWEQEEEDKM---QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667
Query: 64 REEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
+ +G+ + RE+E++ + ++E EQE K + + EK EK
Sbjct: 668 KMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK 710
Score = 33.5 bits (75), Expect = 0.11
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDP---EQSTGNYSEDEQNGKQKWREEGEAG 70
+WE E + R QE + +Q W+Q+ EQ ++E+ +Q R +
Sbjct: 319 MWEQEE-KMREQEEKMW----RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
Query: 71 RKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRL 108
R RE+EK + E+++Q+E+ R RE EK+ + E+ +
Sbjct: 374 RMREQEKMWEQEEKMQEEE---RIREREKKMREEEETM 408
Score = 30.8 bits (68), Expect = 0.72
Identities = 17/75 (22%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
Query: 34 KKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKR 93
++Q W+Q+ E+ ED+ +++ E E + + EK + E+++++++E +
Sbjct: 605 QEQEEKMWEQE-EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE--K 661
Query: 94 KRENEKQKQYPEKRL 108
RE E++ Q E+++
Sbjct: 662 MREQEEKMQGQEEKM 676
Score = 30.4 bits (67), Expect = 0.94
Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 15/156 (9%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKR 73
+WE E + QE E I +K+ + EQ ++E +Q EE E ++R
Sbjct: 381 MWEQE---EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ---EEKEWQQQR 434
Query: 74 EREKEEKN-EKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQES 132
E++EK E+E EQE K + EK + E K +W + K+ QE
Sbjct: 435 LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK----MWRQEKMRE----QED 486
Query: 133 LSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKK 168
E M ++ W + R E + K ++
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522
Score = 28.5 bits (62), Expect = 3.6
Identities = 21/97 (21%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 14 LWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSED--EQNGKQKWREEGEAGR 71
+WE E +E K Q ++ E+ E EQ K + +EE G+
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ 707
Query: 72 KRE---REKEEKNEKELQDEQENKRKRENEKQKQYPE 105
+ + +E++ ++E+++++E R ++ + Q++ PE
Sbjct: 708 EEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
Length = 1113
Score = 44.7 bits (104), Expect = 5e-05
Identities = 25/74 (33%), Positives = 42/74 (56%)
Query: 37 SAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRE 96
SA D E E E+ +++ E E R+REREKE + EKE + E+E +R+ E
Sbjct: 223 SAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELE 282
Query: 97 NEKQKQYPEKRLVS 110
+++++ EK L++
Sbjct: 283 RQREQRAREKELLA 296
Score = 35.8 bits (81), Expect = 0.022
Identities = 14/53 (26%), Positives = 34/53 (64%)
Query: 55 DEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+ +G R + + +RERE+E + E+E + ++E +++RE E++K+ +++
Sbjct: 217 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEK 269
Score = 35.0 bits (79), Expect = 0.038
Identities = 22/97 (22%), Positives = 45/97 (46%)
Query: 12 PALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGR 71
P L + + + + A + Q ++ E+ E E + +++ E E +
Sbjct: 204 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREK 263
Query: 72 KREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRL 108
+RE+EKE + EKE + E E +R++ +++ K L
Sbjct: 264 EREQEKEREREKERERELERQREQRAREKELLAAKAL 300
Score = 29.6 bits (65), Expect = 1.6
Identities = 28/130 (21%), Positives = 58/130 (44%), Gaps = 22/130 (16%)
Query: 47 QSTGNYSEDEQNGKQ------KWREEGEAGRKREREKEEKNEKELQDEQENKRKREN--- 97
QS+ + NG+Q K E R E E+EE +E +E+ KRK +
Sbjct: 965 QSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEA 1024
Query: 98 --EKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRK 155
E +++ E++ + + ++ T +C ++ + + +T +Q+S + R
Sbjct: 1025 VFEAYQEHIEEQNLERQVLQT--------QCRRLE---ARHYSLSLTAEQLSHSVAELRS 1073
Query: 156 KYNKEMSKRK 165
+ K +S+R+
Sbjct: 1074 QKQKMVSERE 1083
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 44.7 bits (104), Expect = 5e-05
Identities = 25/74 (33%), Positives = 42/74 (56%)
Query: 37 SAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRE 96
SA D E E E+ +++ E E R+REREKE + EKE + E+E +R+ E
Sbjct: 327 SAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELE 386
Query: 97 NEKQKQYPEKRLVS 110
+++++ EK L++
Sbjct: 387 RQREQRAREKELLA 400
Score = 35.8 bits (81), Expect = 0.022
Identities = 14/53 (26%), Positives = 34/53 (64%)
Query: 55 DEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+ +G R + + +RERE+E + E+E + ++E +++RE E++K+ +++
Sbjct: 321 ERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEK 373
Score = 35.0 bits (79), Expect = 0.038
Identities = 22/97 (22%), Positives = 45/97 (46%)
Query: 12 PALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGR 71
P L + + + + A + Q ++ E+ E E + +++ E E +
Sbjct: 308 PELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREK 367
Query: 72 KREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRL 108
+RE+EKE + EKE + E E +R++ +++ K L
Sbjct: 368 EREQEKEREREKERERELERQREQRAREKELLAAKAL 404
Score = 29.6 bits (65), Expect = 1.6
Identities = 28/130 (21%), Positives = 58/130 (44%), Gaps = 22/130 (16%)
Query: 47 QSTGNYSEDEQNGKQ------KWREEGEAGRKREREKEEKNEKELQDEQENKRKREN--- 97
QS+ + NG+Q K E R E E+EE +E +E+ KRK +
Sbjct: 1069 QSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEA 1128
Query: 98 --EKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRK 155
E +++ E++ + + ++ T +C ++ + + +T +Q+S + R
Sbjct: 1129 VFEAYQEHIEEQNLERQVLQT--------QCRRLE---ARHYSLSLTAEQLSHSVAELRS 1177
Query: 156 KYNKEMSKRK 165
+ K +S+R+
Sbjct: 1178 QKQKMVSERE 1187
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 44.3 bits (103), Expect = 6e-05
Identities = 19/74 (25%), Positives = 43/74 (58%)
Query: 34 KKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKR 93
KK+ ++ E++ E+E+ GK+K + + + K +++K ++ EK + E+E K+
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 94 KRENEKQKQYPEKR 107
++ K+K+ E+R
Sbjct: 62 RKRKRKKKKEEEER 75
Score = 41.6 bits (96), Expect = 4e-04
Identities = 16/53 (30%), Positives = 38/53 (71%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
E+E+ K+K +++ E + E E+EE+ EKE ++++E +R+++ +K+++ E+
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEE 109
Score = 40.0 bits (92), Expect = 0.001
Identities = 20/62 (32%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Query: 46 EQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPE 105
E+ +++ + K+K EE + RKR+++KEE+ E+E ++E+E + K E EK++
Sbjct: 39 EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEE-EREEEEEEEEEEKEEEEKEEGRRR 97
Query: 106 KR 107
K+
Sbjct: 98 KK 99
Score = 39.7 bits (91), Expect = 0.002
Identities = 22/83 (26%), Positives = 49/83 (59%), Gaps = 7/83 (8%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E + + +E E +K+ +++ E+ E+E+ ++K EE E GR+R ++K
Sbjct: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREE------EEEEEEEEKEEEEKEEGRRR-KKK 100
Query: 78 EEKNEKELQDEQENKRKRENEKQ 100
+++ KE ++E++ KR+R+ +K+
Sbjct: 101 KKRRRKEEEEEKKKKRRRKTKKK 123
Score = 39.3 bits (90), Expect = 0.002
Identities = 29/122 (23%), Positives = 57/122 (46%), Gaps = 14/122 (11%)
Query: 53 SEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDE--QENKRKRENEKQKQYPEKRLVS 110
+E+ + ++ EE + G+++E+ KE++ EKE + + + KRK + E++K+ KR
Sbjct: 10 TEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR--- 66
Query: 111 KSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKH 170
K K +E E + K+ + K +K+ KE + K KK+
Sbjct: 67 ---------KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117
Query: 171 MR 172
+
Sbjct: 118 RK 119
Score = 38.5 bits (88), Expect = 0.003
Identities = 17/67 (25%), Positives = 41/67 (61%), Gaps = 3/67 (4%)
Query: 43 QDPEQSTGNYSE---DEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEK 99
++ E+ G E +++ K+K ++ E +++E+E+EEK K + +++ + +RE E+
Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEE 79
Query: 100 QKQYPEK 106
+++ EK
Sbjct: 80 EEEEEEK 86
Score = 38.1 bits (87), Expect = 0.004
Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKW---REEGEAGRK 72
E E R ++ + KK+ ++ E+ + K+K REE E +
Sbjct: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE 83
Query: 73 REREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSK 111
E+E+EEK E + +++ +R++E E++K+ +R K
Sbjct: 84 EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/92 (20%), Positives = 46/92 (50%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E + +E +K+ + ++ E ++ K+K ++E E + E
Sbjct: 21 EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E+EE+ E+E ++E ++K++ ++K+ E++
Sbjct: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112
Score = 34.3 bits (77), Expect = 0.065
Identities = 24/102 (23%), Positives = 46/102 (45%)
Query: 71 RKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQ 130
+K+++E EE E E +E+E K + EK+K+ +++ K T K K +
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 131 ESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMR 172
E + ++ + + ++ +E +RK KKK R
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRR 105
Score = 30.4 bits (67), Expect = 0.94
Identities = 28/113 (24%), Positives = 49/113 (43%), Gaps = 12/113 (10%)
Query: 60 KQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWA 119
K+K +E E E E+EE+ E + +++++ KRK EK+K+ K +
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRK---EKEKKKKTKETEKRKEKEEEEK 60
Query: 120 KFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMR 172
K K R +E E + + +++ KE +R+ KKK R
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEE---------KEEEEKEEGRRRKKKKKRR 104
Score = 30.0 bits (66), Expect = 1.2
Identities = 11/37 (29%), Positives = 26/37 (70%)
Query: 71 RKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+K++++K+E E E +E E + ++E +++++ EKR
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKR 37
Score = 27.7 bits (60), Expect = 6.1
Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 8/118 (6%)
Query: 60 KQKWREEGEAGRKREREKEEKNEKELQDEQENKRK-----RENEKQKQYPEKRLVSKSLM 114
K+K ++E E + E E EE+ EKE +++ KRK +E +K+ + EKR +
Sbjct: 3 KKKKKKETEETEETE-ETEEEEEKE--GKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEE 59
Query: 115 HTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMR 172
K K + +E E + ++ + + +KK + + + KKK R
Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 44.3 bits (103), Expect = 6e-05
Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 34 KKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKR 93
+K++ P D+D E+ E E+ K++ RE E RKR RE+EE+ ++ +D + KR
Sbjct: 235 RKRTEEP-DRD-ERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKR 292
Query: 94 KRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFE-FDMTHKQISQWFCK 152
R + R S+S H + R + S S + + H+ S+
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR---D 349
Query: 153 TRKKYNKEMSKRKHKKK 169
R+ +++ KH+ K
Sbjct: 350 RRRSKSRDRKSYKHRSK 366
Score = 33.5 bits (75), Expect = 0.11
Identities = 18/47 (38%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 60 KQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
K+K R+ E + ER K+EK E+E + E+E +R+RE ++K+ E+
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQERE-EREKEREREREERERKRRREE 276
Score = 32.7 bits (73), Expect = 0.19
Identities = 16/54 (29%), Positives = 34/54 (62%), Gaps = 5/54 (9%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKNEKELQ-----DEQENKRKRENEKQKQ 102
E+ + +K EE + + ++EK+E+ E+E + +E+E KR+RE E++++
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREK 281
Score = 29.6 bits (65), Expect = 1.6
Identities = 20/101 (19%), Positives = 43/101 (42%), Gaps = 9/101 (8%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEK 80
R R +E + KK+ +++ E+ + + +++ E E R RER K +
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSR 294
Query: 81 ---------NEKELQDEQENKRKRENEKQKQYPEKRLVSKS 112
+++ +++KR R E+++ R S+S
Sbjct: 295 SRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRS 335
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 44.3 bits (103), Expect = 6e-05
Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 34 KKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKR 93
+K++ P D+D E+ E E+ K++ RE E RKR RE+EE+ ++ +D + KR
Sbjct: 235 RKRTEEP-DRD-ERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKR 292
Query: 94 KRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFE-FDMTHKQISQWFCK 152
R + R S+S H + R + S S + + H+ S+
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSR---D 349
Query: 153 TRKKYNKEMSKRKHKKK 169
R+ +++ KH+ K
Sbjct: 350 RRRSKSRDRKSYKHRSK 366
Score = 33.5 bits (75), Expect = 0.11
Identities = 18/47 (38%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 60 KQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEK 106
K+K R+ E + ER K+EK E+E + E+E +R+RE ++K+ E+
Sbjct: 231 KEKLRKRTEEPDRDERLKKEKQERE-EREKEREREREERERKRRREE 276
Score = 32.7 bits (73), Expect = 0.19
Identities = 16/54 (29%), Positives = 34/54 (62%), Gaps = 5/54 (9%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKNEKELQ-----DEQENKRKRENEKQKQ 102
E+ + +K EE + + ++EK+E+ E+E + +E+E KR+RE E++++
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREK 281
Score = 29.6 bits (65), Expect = 1.6
Identities = 20/101 (19%), Positives = 43/101 (42%), Gaps = 9/101 (8%)
Query: 21 RSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEK 80
R R +E + KK+ +++ E+ + + +++ E E R RER K +
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSR 294
Query: 81 ---------NEKELQDEQENKRKRENEKQKQYPEKRLVSKS 112
+++ +++KR R E+++ R S+S
Sbjct: 295 SRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRS 335
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 43.9 bits (102), Expect = 8e-05
Identities = 21/54 (38%), Positives = 37/54 (68%), Gaps = 1/54 (1%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKE-EKNEKELQDEQENKRKRENEKQKQYPEK 106
E+++ K+K +++ + +K+++EKE EK EKE + E+ + KRE EK+K EK
Sbjct: 691 EEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEK 744
Score = 40.4 bits (93), Expect = 0.001
Identities = 16/47 (34%), Positives = 36/47 (76%)
Query: 61 QKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKR 107
+K EE E +++E++K++K +K+ +++++ K+++E EK+K+ EKR
Sbjct: 687 EKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKR 733
Score = 39.7 bits (91), Expect = 0.002
Identities = 29/116 (25%), Positives = 58/116 (50%), Gaps = 1/116 (0%)
Query: 57 QNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHT 116
++G + +E +K++REK +K++ + + E+ + RE++ + P L K L
Sbjct: 605 KDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALP 664
Query: 117 LWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMR 172
L++ +R P + SL L + ++ + K +KK KE K+K K+K +
Sbjct: 665 LFSPATASRVPAMLPSL-LPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKK 719
Score = 39.3 bits (90), Expect = 0.002
Identities = 24/105 (22%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Query: 64 REEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKL 123
++E + R+RE++K + KE +E ++ +E ++ +YP K + + KFK+
Sbjct: 535 KKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPY--KFKI 592
Query: 124 NRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKK 168
+ + L K+ + K R+K K+ KR+ +K
Sbjct: 593 KEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEK 637
Score = 32.3 bits (72), Expect = 0.25
Identities = 15/47 (31%), Positives = 32/47 (68%), Gaps = 1/47 (2%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKE-EKNEKELQDEQENKRKRENEK 99
E +++ K+K +++ + K+E+E+E EK E+E +++++ K K E K
Sbjct: 700 EKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIK 746
Score = 31.6 bits (70), Expect = 0.42
Identities = 14/43 (32%), Positives = 27/43 (62%)
Query: 54 EDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRE 96
++++ K+K +E+ E R++E+ + EK EKE + + K K E
Sbjct: 706 KEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVE 748
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 43.5 bits (101), Expect = 1e-04
Identities = 22/82 (26%), Positives = 43/82 (52%)
Query: 22 SRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKN 81
S+G E ++ L ++ A P + P + Y +QK +++ + ++ E E+EE+
Sbjct: 1082 SKGDETQSDLLGARKKAFPPPRPPPPNWEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEE 1141
Query: 82 EKELQDEQENKRKRENEKQKQY 103
E+E ++E+E + E E QY
Sbjct: 1142 EEEEEEEEEEAEEEEEELPPQY 1163
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 43.1 bits (100), Expect = 1e-04
Identities = 21/87 (24%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 15 WEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRE 74
W E R +E + K S+ WD++ E+S E E + ++W E R RE
Sbjct: 2123 WSRERDWDRPREWDR--HRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRE 2180
Query: 75 REKEEKNEKELQDEQENKRKRENEKQK 101
RE++ + +++ +E R + ++++
Sbjct: 2181 RERDRRRDRDRSRSRERDRDKARDRER 2207
Score = 32.7 bits (73), Expect = 0.19
Identities = 15/56 (26%), Positives = 26/56 (46%)
Query: 56 EQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSK 111
+++ + W E R+RE+E KE +E R RE E+ ++ R S+
Sbjct: 2140 DKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSR 2195
Score = 29.6 bits (65), Expect = 1.6
Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 41 WDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQ 100
WD+ P + + +D + RE A R RERE + E + E+ R+RE +++
Sbjct: 2129 WDR-PREWDRHRDKDSSRDWDRNRERS-ANRDREREADRGKEWDRSRERSRNRERERDRR 2186
Query: 101 KQYPEKR 107
+ R
Sbjct: 2187 RDRDRSR 2193
Score = 29.3 bits (64), Expect = 2.1
Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 6/71 (8%)
Query: 43 QDPEQSTGNYSEDEQNGK-QKWREEGEAGRKRER-----EKEEKNEKELQDEQENKRKRE 96
Q PE S D + GK ++R + GR+RER +++ E + Q R+RE
Sbjct: 2057 QGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRE 2116
Query: 97 NEKQKQYPEKR 107
E+ + + +R
Sbjct: 2117 RERGRNWSRER 2127
>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
Length = 936
Score = 43.1 bits (100), Expect = 1e-04
Identities = 40/157 (25%), Positives = 79/157 (50%), Gaps = 13/157 (8%)
Query: 9 PVIPALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWRE-EG 67
P++ A+ E R+ E ILA KK+ Q+ E+ +++E+ K++ E E
Sbjct: 656 PILKAMEERAIQRA---ECRRILAEKKKK-----QEEEKLAQLKAQEEERQKREAEEKEA 707
Query: 68 EAGRKREREKEEKNEKELQDEQENKRKRENEK-QKQYPEKRLVSKSLMHTLWAKFKLNRC 126
+ RKRE EK K KEL+ ++ KR ++ E K++ E+ L+ K + W + ++
Sbjct: 708 QLERKRE-EKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEP-WKRLRMQSK 765
Query: 127 PTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSK 163
IQ + + + K + WF ++++ ++M++
Sbjct: 766 QNIQVA-EEHYSLFLQRKYMLTWFQRSQESLARKMAQ 801
Score = 29.6 bits (65), Expect = 1.6
Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 68 EAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTL-WAKFKLNRC 126
+ GRK ++K+++ + L E +K+ +EN ++ EK L + + TL + F +C
Sbjct: 173 DLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRR---EKELEYQRIEKTLKKSAFLEAQC 229
Query: 127 PTIQESLSLSFEFDMTHKQISQWFCKTRKK 156
+E + E ++I + K R++
Sbjct: 230 LVQEEKKRKALEAKKEEEEIQREMVKLRRE 259
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 42.7 bits (99), Expect = 2e-04
Identities = 22/87 (25%), Positives = 47/87 (54%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E + R ++ E +Q ++D E+ T ++E ++ +++ E E R RER
Sbjct: 65 EKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRER 124
Query: 76 EKEEKNEKELQDEQENKRKRENEKQKQ 102
EK+++ +E Q ++E R+RE + +++
Sbjct: 125 EKQKEMGRERQTDRETDRERERQAERE 151
Score = 41.6 bits (96), Expect = 4e-04
Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R R +E E ++++ + D E+ E E+ ++ ++ E GR+R+
Sbjct: 77 ERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQT 136
Query: 76 EKEEKNEKELQDEQENK-----------RKRENEKQKQYPEKRLVSKSLMHT 116
++E E+E Q E+E + R+RE E++++ KR + HT
Sbjct: 137 DRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHT 188
Score = 41.2 bits (95), Expect = 5e-04
Identities = 19/86 (22%), Positives = 47/86 (54%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
+ E GR R + ET ++Q+ + E+ T + + + +++ RE ++RER
Sbjct: 127 QKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERER 186
Query: 76 EKEEKNEKELQDEQENKRKRENEKQK 101
+ + E++ + +++ R+RE+E+++
Sbjct: 187 HTDMERERQRETDRKRDRQRESERER 212
Score = 39.3 bits (90), Expect = 0.002
Identities = 25/95 (26%), Positives = 49/95 (51%), Gaps = 10/95 (10%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E R R +E + + ++Q+ D++ E+ + + G+++ E+ R RER
Sbjct: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQA---ERERETGRERKTED----RHRER 167
Query: 76 EKEEKNEKELQDEQENKRKR---ENEKQKQYPEKR 107
E+E K E+E + E + + + E E+Q++ KR
Sbjct: 168 ERERKRERERKRETKERERHTDMERERQRETDRKR 202
Score = 38.5 bits (88), Expect = 0.003
Identities = 20/90 (22%), Positives = 45/90 (50%)
Query: 18 EAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREK 77
E R R +E +T ++Q D+D ++ T + E+ + + E +++ERE
Sbjct: 57 ERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREM 116
Query: 78 EEKNEKELQDEQENKRKRENEKQKQYPEKR 107
E ++E + ++E R+R+ +++ +R
Sbjct: 117 ERVRDREREKQKEMGRERQTDRETDRERER 146
Score = 38.1 bits (87), Expect = 0.004
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWRE-----EGEAG 70
E + R R +E +T + S +D E++ D + KQ RE E E
Sbjct: 26 ETDRERDRAKESKT---EDRHSERDRQRDRERNRER-DRDREREKQTDREGERQRERERD 81
Query: 71 RKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRL 108
R R+RE E + +KE + ++ + RE +KQK+ +R+
Sbjct: 82 RDRQRETERERDKERETDRHTETDRERQKQKEREMERV 119
Score = 34.3 bits (77), Expect = 0.065
Identities = 15/72 (20%), Positives = 39/72 (54%)
Query: 42 DQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQK 101
D+D E+ E E+ +++ + + +RER+KE + ++ + ++E ++++E E ++
Sbjct: 59 DRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMER 118
Query: 102 QYPEKRLVSKSL 113
+R K +
Sbjct: 119 VRDREREKQKEM 130
Score = 31.2 bits (69), Expect = 0.55
Identities = 16/56 (28%), Positives = 34/56 (60%), Gaps = 6/56 (10%)
Query: 52 YSEDEQNGKQKWREEGEAGRKREREKEEK-----NEKELQDEQENKRKRENEKQKQ 102
++E E +Q+ R E R+R+R KE K +E++ Q ++E R+R+ +++++
Sbjct: 11 HTETETMDRQRERRR-ETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 42.7 bits (99), Expect = 2e-04
Identities = 25/83 (30%), Positives = 43/83 (51%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
EAE + +EIE+ + +S + + E T SEDE + + + E E ++E
Sbjct: 80 EAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQES 139
Query: 76 EKEEKNEKELQDEQENKRKRENE 98
E EE N++E + E E + + E+E
Sbjct: 140 EAEEDNQEEGESEAEGETEAESE 162
Score = 39.7 bits (91), Expect = 0.002
Identities = 19/73 (26%), Positives = 44/73 (60%), Gaps = 4/73 (5%)
Query: 32 ANKKQSAMPWDQD----PEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQD 87
A K+++ + +Q+ E + SE+E +++ E E+ + + E EE +E+E++D
Sbjct: 76 AGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMED 135
Query: 88 EQENKRKRENEKQ 100
EQE++ + +N+++
Sbjct: 136 EQESEAEEDNQEE 148
Score = 36.6 bits (83), Expect = 0.013
Identities = 19/76 (25%), Positives = 37/76 (48%)
Query: 31 LANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQE 90
LA + W + E E +Q+ E EAG + E E+E ++E+E + E+E
Sbjct: 57 LAEYVHGSQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEE 116
Query: 91 NKRKRENEKQKQYPEK 106
++ + + E ++ E+
Sbjct: 117 SEDESDEESEEDSEEE 132
Score = 32.3 bits (72), Expect = 0.25
Identities = 19/86 (22%), Positives = 39/86 (45%)
Query: 16 EAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKRER 75
E E G+E E+ ++ + +++ E + SE++ + + +E EA +
Sbjct: 88 EREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQE 147
Query: 76 EKEEKNEKELQDEQENKRKRENEKQK 101
E E + E E + E E + E E ++
Sbjct: 148 EGESEAEGETEAESEFDPEIEMEAER 173
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.125 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,196,968
Number of Sequences: 37866
Number of extensions: 396023
Number of successful extensions: 16502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 659
Number of HSP's successfully gapped in prelim test: 480
Number of HSP's that attempted gapping in prelim test: 5170
Number of HSP's gapped (non-prelim): 5964
length of query: 188
length of database: 18,247,518
effective HSP length: 96
effective length of query: 92
effective length of database: 14,612,382
effective search space: 1344339144
effective search space used: 1344339144
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.