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Search of human proteins with 223890257
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223890257 midline 2 isoform 1 [Homo sapiens]
(735 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223890257 midline 2 isoform 1 [Homo sapiens] 1513 0.0
gi|223890259 midline 2 isoform 2 [Homo sapiens] 1429 0.0
gi|148833499 midline 1 [Homo sapiens] 1074 0.0
gi|4557753 midline 1 [Homo sapiens] 1074 0.0
gi|15451852 midline 1 [Homo sapiens] 1074 0.0
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 217 4e-56
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 196 5e-50
gi|89886468 fibronectin type III and SPRY domain containing 1-li... 192 7e-49
gi|13236585 fibronectin type III and SPRY domain containing 1 [H... 191 2e-48
gi|223718222 fibronectin type III and SPRY domain containing 1-l... 191 2e-48
gi|134288906 tripartite motif-containing 67 [Homo sapiens] 189 8e-48
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens] 186 5e-47
gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 177 3e-44
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] 159 7e-39
gi|68160937 tripartite motif-containing 25 [Homo sapiens] 140 3e-33
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 125 1e-28
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 124 3e-28
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 124 3e-28
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 124 3e-28
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] 113 7e-25
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] 108 2e-23
gi|148596968 tripartite motif-containing 8 [Homo sapiens] 105 1e-22
gi|28195390 tripartite motif-containing 42 [Homo sapiens] 103 4e-22
gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens] 89 1e-17
gi|15208643 ADP-ribosylation factor domain protein 1 isoform gam... 89 2e-17
gi|15208641 ADP-ribosylation factor domain protein 1 isoform bet... 89 2e-17
gi|4502197 ADP-ribosylation factor domain protein 1 isoform alph... 89 2e-17
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 82 2e-15
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 82 2e-15
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 82 2e-15
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 1513 bits (3916), Expect = 0.0
Identities = 735/735 (100%), Positives = 735/735 (100%)
Query: 1 MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS 60
MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS
Sbjct: 1 MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS 60
Query: 61 SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES 120
SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES
Sbjct: 61 SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES 120
Query: 121 RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR 180
RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR
Sbjct: 121 RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR 180
Query: 181 LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK 240
LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK
Sbjct: 181 LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK 240
Query: 241 QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI
Sbjct: 241 QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
Query: 301 AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA 360
AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA
Sbjct: 301 AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA 360
Query: 361 MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT 420
MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT
Sbjct: 361 MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT 420
Query: 421 VHWISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGL 480
VHWISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGL
Sbjct: 421 VHWISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGL 480
Query: 481 YNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDP 540
YNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDP
Sbjct: 481 YNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDP 540
Query: 541 KMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSS 600
KMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSS
Sbjct: 541 KMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSS 600
Query: 601 TWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDY 660
TWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDY
Sbjct: 601 TWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDY 660
Query: 661 DNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNC 720
DNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNC
Sbjct: 661 DNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNC 720
Query: 721 RPQESPYVSGMKTCH 735
RPQESPYVSGMKTCH
Sbjct: 721 RPQESPYVSGMKTCH 735
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 1429 bits (3699), Expect = 0.0
Identities = 705/735 (95%), Positives = 705/735 (95%), Gaps = 30/735 (4%)
Query: 1 MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS 60
MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS
Sbjct: 1 MGESPASVVLNASGGLFSLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVS 60
Query: 61 SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES 120
SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES
Sbjct: 61 SCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSES 120
Query: 121 RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR 180
RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR
Sbjct: 121 RRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR 180
Query: 181 LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK 240
LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK
Sbjct: 181 LVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLK 240
Query: 241 QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI
Sbjct: 241 QTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMI 300
Query: 301 AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA 360
AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA
Sbjct: 301 AVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVA 360
Query: 361 MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT 420
MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT
Sbjct: 361 MATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTIT 420
Query: 421 VHWISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGL 480
VHWISDDEFSISSYELQYTIFTGQANFIS L
Sbjct: 421 VHWISDDEFSISSYELQYTIFTGQANFIS------------------------------L 450
Query: 481 YNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDP 540
YNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDP
Sbjct: 451 YNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDP 510
Query: 541 KMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSS 600
KMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSS
Sbjct: 511 KMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSS 570
Query: 601 TWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDY 660
TWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDY
Sbjct: 571 TWYAIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDY 630
Query: 661 DNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNC 720
DNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNC
Sbjct: 631 DNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQECNC 690
Query: 721 RPQESPYVSGMKTCH 735
RPQESPYVSGMKTCH
Sbjct: 691 RPQESPYVSGMKTCH 705
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 1074 bits (2778), Expect = 0.0
Identities = 507/695 (72%), Positives = 590/695 (84%), Gaps = 30/695 (4%)
Query: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80
METLESELTCPICLELFEDPLLLPCAHSLCF+CAHRILVS C++ ES+E ITAFQCPTCR
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
Query: 81 YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140
+VI+L+ RGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE+RRER + T S+E++ CQ
Sbjct: 61 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
Query: 141 FCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHEN 200
FC+QDP +DAVKTC+TCEVSYCD CL+ATHPNKKPFT HRL+EP+PD+H+RG+ CL+HE+
Sbjct: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
Query: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
EKVNMYCV+DDQLICALCKLVGRHRDHQVA+L++R++KLKQ LE NLTNL+KRN+ELE
Sbjct: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
Query: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
+AKLIQ CQ VEVN + EAKL EECD L+EIIQQR+Q+I KIKE KVM+LRKLAQQ+A
Sbjct: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFE 380
NC+QC+ERS LI+QAEH LKEND ARFLQ+AKNI ERV+MATASSQVLIP+IN ND F+
Sbjct: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
Query: 381 NFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTI 440
FALDFSREKKLLE LDYLTAPNPP+IREELCTAS+DTITVHW SDDEFS+ SYELQYTI
Sbjct: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
Query: 441 FTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPNIKQNHYTV 500
FTGQAN +S L NS DSWMIVPNIKQNHYTV
Sbjct: 421 FTGQANVVS------------------------------LCNSADSWMIVPNIKQNHYTV 450
Query: 501 HGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDE 560
HGLQSGT+YIF+VKAINQAGSR+SEP +LKTNSQPFKLDPK H+KLK+S+D L +E+DE
Sbjct: 451 HGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDE 510
Query: 561 SSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGK 620
SS KKSHTPERF+ G YG AGN+FIDSG HYWEVV+ STWYAIG+AYKSAPK+EWIGK
Sbjct: 511 SSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGK 570
Query: 621 NASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFD 680
N++SW RCN+N+VVRHN+KE+ ++ PHL+R+G+LLDYDN ++FYD NS+HL+TFD
Sbjct: 571 NSASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFD 630
Query: 681 VTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPER 715
V F PVCPTFT+WNK L I++GLP PD +D E+
Sbjct: 631 VAFAQPVCPTFTVWNKCLTIITGLPIPDHLDCTEQ 665
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 1074 bits (2778), Expect = 0.0
Identities = 507/695 (72%), Positives = 590/695 (84%), Gaps = 30/695 (4%)
Query: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80
METLESELTCPICLELFEDPLLLPCAHSLCF+CAHRILVS C++ ES+E ITAFQCPTCR
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
Query: 81 YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140
+VI+L+ RGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE+RRER + T S+E++ CQ
Sbjct: 61 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
Query: 141 FCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHEN 200
FC+QDP +DAVKTC+TCEVSYCD CL+ATHPNKKPFT HRL+EP+PD+H+RG+ CL+HE+
Sbjct: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
Query: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
EKVNMYCV+DDQLICALCKLVGRHRDHQVA+L++R++KLKQ LE NLTNL+KRN+ELE
Sbjct: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
Query: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
+AKLIQ CQ VEVN + EAKL EECD L+EIIQQR+Q+I KIKE KVM+LRKLAQQ+A
Sbjct: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFE 380
NC+QC+ERS LI+QAEH LKEND ARFLQ+AKNI ERV+MATASSQVLIP+IN ND F+
Sbjct: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
Query: 381 NFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTI 440
FALDFSREKKLLE LDYLTAPNPP+IREELCTAS+DTITVHW SDDEFS+ SYELQYTI
Sbjct: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
Query: 441 FTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPNIKQNHYTV 500
FTGQAN +S L NS DSWMIVPNIKQNHYTV
Sbjct: 421 FTGQANVVS------------------------------LCNSADSWMIVPNIKQNHYTV 450
Query: 501 HGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDE 560
HGLQSGT+YIF+VKAINQAGSR+SEP +LKTNSQPFKLDPK H+KLK+S+D L +E+DE
Sbjct: 451 HGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDE 510
Query: 561 SSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGK 620
SS KKSHTPERF+ G YG AGN+FIDSG HYWEVV+ STWYAIG+AYKSAPK+EWIGK
Sbjct: 511 SSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGK 570
Query: 621 NASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFD 680
N++SW RCN+N+VVRHN+KE+ ++ PHL+R+G+LLDYDN ++FYD NS+HL+TFD
Sbjct: 571 NSASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFD 630
Query: 681 VTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPER 715
V F PVCPTFT+WNK L I++GLP PD +D E+
Sbjct: 631 VAFAQPVCPTFTVWNKCLTIITGLPIPDHLDCTEQ 665
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 1074 bits (2778), Expect = 0.0
Identities = 507/695 (72%), Positives = 590/695 (84%), Gaps = 30/695 (4%)
Query: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCR 80
METLESELTCPICLELFEDPLLLPCAHSLCF+CAHRILVS C++ ES+E ITAFQCPTCR
Sbjct: 1 METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCR 60
Query: 81 YVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQ 140
+VI+L+ RGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE+RRER + T S+E++ CQ
Sbjct: 61 HVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQ 120
Query: 141 FCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHEN 200
FC+QDP +DAVKTC+TCEVSYCD CL+ATHPNKKPFT HRL+EP+PD+H+RG+ CL+HE+
Sbjct: 121 FCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHED 180
Query: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
EKVNMYCV+DDQLICALCKLVGRHRDHQVA+L++R++KLKQ LE NLTNL+KRN+ELE
Sbjct: 181 EKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETL 240
Query: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
+AKLIQ CQ VEVN + EAKL EECD L+EIIQQR+Q+I KIKE KVM+LRKLAQQ+A
Sbjct: 241 LAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIA 300
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFE 380
NC+QC+ERS LI+QAEH LKEND ARFLQ+AKNI ERV+MATASSQVLIP+IN ND F+
Sbjct: 301 NCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFD 360
Query: 381 NFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTI 440
FALDFSREKKLLE LDYLTAPNPP+IREELCTAS+DTITVHW SDDEFS+ SYELQYTI
Sbjct: 361 TFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTI 420
Query: 441 FTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPNIKQNHYTV 500
FTGQAN +S L NS DSWMIVPNIKQNHYTV
Sbjct: 421 FTGQANVVS------------------------------LCNSADSWMIVPNIKQNHYTV 450
Query: 501 HGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDE 560
HGLQSGT+YIF+VKAINQAGSR+SEP +LKTNSQPFKLDPK H+KLK+S+D L +E+DE
Sbjct: 451 HGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDE 510
Query: 561 SSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGK 620
SS KKSHTPERF+ G YG AGN+FIDSG HYWEVV+ STWYAIG+AYKSAPK+EWIGK
Sbjct: 511 SSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGK 570
Query: 621 NASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFD 680
N++SW RCN+N+VVRHN+KE+ ++ PHL+R+G+LLDYDN ++FYD NS+HL+TFD
Sbjct: 571 NSASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFD 630
Query: 681 VTFILPVCPTFTIWNKSLMILSGLPAPDFIDYPER 715
V F PVCPTFT+WNK L I++GLP PD +D E+
Sbjct: 631 VAFAQPVCPTFTVWNKCLTIITGLPIPDHLDCTEQ 665
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 217 bits (552), Expect = 4e-56
Identities = 128/455 (28%), Positives = 231/455 (50%), Gaps = 63/455 (13%)
Query: 21 METLESELTCPICLELFEDPLLLPCAHSLCFSCAHRIL---------VSSCSSGESIEPI 71
++ +E EL CP C ELF PL+LPC HS+C C +L V S +S +S +
Sbjct: 24 IKNIERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDDSFNDVGSDNSNQSSPRL 83
Query: 72 ---------------------------TAFQCPTCRYVISLNHRGLDGLKRNVTLQNIID 104
T F CP C + + L RG++GL RN TL+ I++
Sbjct: 84 RLPSPSMDKIDRINRPGWKRNSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVE 143
Query: 105 RFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDR 164
R+++A+ R TA I C C+ PP+++ K+C+ C SYC+
Sbjct: 144 RYRQAA----------------RAATA-----IMCDLCKP-PPQESTKSCMDCSASYCNE 181
Query: 165 CLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKVNMYCVSDDQLICALCKLVGRH 224
C + HP H V P + + + C +HE E++NMYC + +C LCKL G H
Sbjct: 182 CFKIHHPWGTIKAQHEYVGPTTNFRPKILMCPEHETERINMYCELCRRPVCHLCKLGGNH 241
Query: 225 RDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLME 284
+H+V +++ ++ LK+ L ++ L+ + S++++Q+++L + ++ E N + + +
Sbjct: 242 ANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEAIT 301
Query: 285 ECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKEND 344
++L E++++RK + I +K ++L K Q+ + LE + L+ A+ +LKE D
Sbjct: 302 HFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENNG-LVGYAQEVLKETD 360
Query: 345 QARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAP-N 403
Q+ F+Q+AK + R+ AT S + P +FE++ ++ S++ +LL L + ++ +
Sbjct: 361 QSCFVQTAKQLHLRIQKATESLKSFRPAA--QTSFEDYVVNTSKQTELLGELSFFSSGID 418
Query: 404 PPSIREELCTASHDTITVHWISDDEFSISSYELQY 438
P I EE ++ + ++W ++ SY L+Y
Sbjct: 419 VPEINEEQSKVYNNAL-INWHHPEKDKADSYVLEY 452
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 196 bits (499), Expect = 5e-50
Identities = 179/772 (23%), Positives = 307/772 (39%), Gaps = 162/772 (20%)
Query: 18 SLKMETLESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEP------- 70
S M+ +E EL CP+C E+++ PL+LPC H++C +CA +L G +P
Sbjct: 21 STSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSP 80
Query: 71 --------------------------------------------ITAFQCPTCRYVISLN 86
+ F CP C+ + L
Sbjct: 81 ASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELG 140
Query: 87 HRGLDGLKRNVTLQNIIDRF-QKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCEQD 145
RGL GL RN+TL+ +++R+ Q SV G I CQ C+
Sbjct: 141 ERGLAGLFRNLTLERVVERYRQSVSVGGA----------------------ILCQLCKP- 177
Query: 146 PPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKVNM 205
PP +A K C C ++C+ C + HP H P +G+ C DH+ E+V
Sbjct: 178 PPLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDHK-EEVTH 236
Query: 206 YCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAKLI 265
YC + +L+C LC++ H H++ + ++ LK L +LT ++ ++ Q+ +L
Sbjct: 237 YCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELE 296
Query: 266 QICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCRQC 325
+ + EV+ + ++ + L ++++++ + I+E + +L +L+ Q+ R
Sbjct: 297 EAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSL 356
Query: 326 LERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFALD 385
L+ S L+ A+ +LKE DQ F+Q+AK + R+A AT + Q P + +F + LD
Sbjct: 357 LDGSG-LVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAA--SSSFRHCQLD 413
Query: 386 FSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYTIFTGQA 445
RE KLL L++L P P I + T ++D I + W
Sbjct: 414 VGREMKLLTELNFLRVPEAPVIDTQR-TFAYDQIFLCW---------------------- 450
Query: 446 NFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPNIKQNHYTVHGLQS 505
S +W E R+ G R W ++ + +
Sbjct: 451 RLPPHSPPAWHYTVEFRR----TDVPAQPGPTR--------WQRREEVRGTSALLENPDT 498
Query: 506 GTRYIFIVKAINQAG-SRNSEPTRLKTNSQP---FKLDPK--MTHKKLKISNDGLQMEKD 559
G+ Y+ V+ N+AG SE L T P F LD + + ++L IS D + +
Sbjct: 499 GSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSRWGASRERLAISKD-QRAVRS 557
Query: 560 ESSLKKSHTPERFSGTGCYGAA----GNIFIDSGCHYWEVVMGSSTWYA-IGIAYKSAPK 614
L +R TGC+ + G++ + G YW + +++ +G+ +S +
Sbjct: 558 VPGLPLLLAADRLL-TGCHLSVDVVLGDVAVTQGRSYWACAVDPASYLVKVGVGLESKLQ 616
Query: 615 NEWIG------------------------KNASSWVF-----------SRCNSNFVVRHN 639
+ G + + + F S +SN +
Sbjct: 617 ESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIGMGKILLGSGASSNAGLTGR 676
Query: 640 NKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTF 691
+ P RLG+ LDY+ +SF D + L + PVCP F
Sbjct: 677 DGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDCSGPVCPAF 728
>gi|89886468 fibronectin type III and SPRY domain containing 1-like
isoform 1 [Homo sapiens]
Length = 498
Score = 192 bits (489), Expect = 7e-49
Identities = 143/514 (27%), Positives = 243/514 (47%), Gaps = 72/514 (14%)
Query: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQM 299
K+ L+ ++ L +N E++N + L + V+ N++ ++L EE D L I+ + K+
Sbjct: 5 KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
Query: 300 IAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359
+ IK+ + K ++L Q++ C LE S L+ A L + F ++A+ I +RV
Sbjct: 65 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
Query: 360 AMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI 419
MA+A L P ++ D + +DFS+E+++L+ L +L P P I C + +++
Sbjct: 125 TMASAFRLSLKPKVS--DNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 182
Query: 420 TVHW-ISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPR 478
TV W + +++ I + L++ + NF G PR
Sbjct: 183 TVAWRMPEEDNKIDHFILEHR----KTNF--------------------------DGLPR 212
Query: 479 GLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYI-FIVKAINQA-GSRNSEPTRLKTNSQPF 536
W I+ NIK YT+ GL+ ++Y+ F V+A N+A S+P L+T + F
Sbjct: 213 --VKDERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNF 270
Query: 537 KLDPKMTHKKLKISNDGLQMEK-----DESSLK------KSHTP---------------- 569
LD +H LK+ + ++ + ES +K +S TP
Sbjct: 271 NLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRG 330
Query: 570 --ERFSGTGCYGAAGNIFIDSGCHYWEV-VMGSSTWYAIGIAYKSAPKNEWIGKNASSWV 626
+RF+G Y G+ I+SG HYWEV Y++G+AYK+ K + +GK +SW
Sbjct: 331 SRDRFTGES-YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWC 389
Query: 627 FSRCN---SNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTF 683
N + F +HNNK +DV +++GV D+D LSFYD + L++F F
Sbjct: 390 IHVNNWLQNTFAAKHNNKVKALDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKF 448
Query: 684 ILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQE 717
PV P F +W L + +G+ P + ++ E
Sbjct: 449 TQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSE 482
>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
sapiens]
Length = 496
Score = 191 bits (485), Expect = 2e-48
Identities = 145/512 (28%), Positives = 237/512 (46%), Gaps = 73/512 (14%)
Query: 237 EKLKQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQR 296
E+ ++ L + L +N E+++ + L Q+ VE N+A + L E L ++++
Sbjct: 2 EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
Query: 297 KQMIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIA 356
K+ + +KIK+ + + +L Q+A C + LE S L+ A L+ D F Q+AK I
Sbjct: 62 KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQIK 121
Query: 357 ERVAMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASH 416
+ V MA A L ++ D + +DF++E+++L+ L +L P+ P I +
Sbjct: 122 DGVTMAPAFRLSLKAKVS--DNMSHLMVDFAQERQMLQALKFLPVPSAPVIDLAESLVAD 179
Query: 417 DTITVHW-ISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAG 475
+ +T+ W + D++ I Y L+Y + NF G
Sbjct: 180 NCVTLVWRMPDEDSKIDHYVLEYR----RTNF--------------------------EG 209
Query: 476 APRGLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYI-FIVKAINQA-GSRNSEPTRLKTNS 533
PR WM++ I+Q YT+ GL+ +Y+ F VKA N+A SEP L+T +
Sbjct: 210 PPR--LKEDQPWMVIEGIRQTEYTLTGLKFDMKYMNFRVKACNKAVAGEFSEPVTLETPA 267
Query: 534 QPFKLDPKMTHKKLKISNDGLQM-------------EKD---------ESSLKKSHTPER 571
F+LD +H+ L++ + ++ EKD S + + +P+R
Sbjct: 268 FMFRLDASTSHQNLRVDDLSVEWDAMGGKVQDIKAREKDGKGRTASPINSPARGTPSPKR 327
Query: 572 F-SGTG--------CYGAAGNIFIDSGCHYWEV-VMGSSTWYAIGIAYKSAPKNEWIGKN 621
SG G Y G+ ID G HYWEV S + +G+AY+S + E +GK
Sbjct: 328 MPSGRGGRDRFTAESYTVLGDTLIDGGEHYWEVRYEPDSKAFGVGVAYRSLGRFEQLGKT 387
Query: 622 ASSWVFSRCN---SNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHT 678
A+SW N +F +H NK ++D P LGV D+ +LSFY+ LHT
Sbjct: 388 AASWCLHVNNWLQVSFTAKHANKVKVLDAPVP-DCLGVHCDFHQGLLSFYNARTKQVLHT 446
Query: 679 FDVTFILPVCPTFTIWNKSLMILSGLPAPDFI 710
F F P+ P FT+W S + +GL P +
Sbjct: 447 FKTRFTQPLLPAFTVWCGSFQVTTGLQVPSAV 478
>gi|223718222 fibronectin type III and SPRY domain containing 1-like
isoform 3 [Homo sapiens]
Length = 530
Score = 191 bits (485), Expect = 2e-48
Identities = 142/514 (27%), Positives = 243/514 (47%), Gaps = 72/514 (14%)
Query: 240 KQTLEMNLTNLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQM 299
++ L+ ++ L +N E++N + L + V+ N++ ++L EE D L I+ + K+
Sbjct: 37 QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 96
Query: 300 IAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERV 359
+ IK+ + K ++L Q++ C LE S L+ A L + F ++A+ I +RV
Sbjct: 97 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 156
Query: 360 AMATASSQVLIPDINFNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTI 419
MA+A L P ++ D + +DFS+E+++L+ L +L P P I C + +++
Sbjct: 157 TMASAFRLSLKPKVS--DNMTHLMVDFSQERQMLQTLKFLPVPKAPEIDPVECLVADNSV 214
Query: 420 TVHW-ISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPR 478
TV W + +++ I + L++ + NF G PR
Sbjct: 215 TVAWRMPEEDNKIDHFILEHR----KTNF--------------------------DGLPR 244
Query: 479 GLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYI-FIVKAINQA-GSRNSEPTRLKTNSQPF 536
W I+ NIK YT+ GL+ ++Y+ F V+A N+A S+P L+T + F
Sbjct: 245 --VKDERCWEIIDNIKGTEYTLSGLKFDSKYMNFRVRACNKAVAGEYSDPVTLETKALNF 302
Query: 537 KLDPKMTHKKLKISNDGLQMEK-----DESSLK------KSHTP---------------- 569
LD +H LK+ + ++ + ES +K +S TP
Sbjct: 303 NLDNSSSHLNLKVEDTCVEWDPTGGKGQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRG 362
Query: 570 --ERFSGTGCYGAAGNIFIDSGCHYWEV-VMGSSTWYAIGIAYKSAPKNEWIGKNASSWV 626
+RF+G Y G+ I+SG HYWEV Y++G+AYK+ K + +GK +SW
Sbjct: 363 SRDRFTGES-YTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTLGKFDQLGKTNTSWC 421
Query: 627 FSRCN---SNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTF 683
N + F +HNNK +DV +++GV D+D LSFYD + L++F F
Sbjct: 422 IHVNNWLQNTFAAKHNNKVKALDVTVP-EKIGVFCDFDGGQLSFYDANSKQLLYSFKTKF 480
Query: 684 ILPVCPTFTIWNKSLMILSGLPAPDFIDYPERQE 717
PV P F +W L + +G+ P + ++ E
Sbjct: 481 TQPVLPGFMVWCGGLSLSTGMQVPSAVRTLQKSE 514
>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
Length = 783
Score = 189 bits (480), Expect = 8e-48
Identities = 166/671 (24%), Positives = 275/671 (40%), Gaps = 144/671 (21%)
Query: 60 SSCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE 119
++CSS S ++ CP C SL+HRGL G +RN L+ I+ R+Q+
Sbjct: 145 AACSSLSSSS--SSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQG---------- 192
Query: 120 SRRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSH 179
R P T+ ++ CQ C++ PP A C C+V YC C HP++ PF H
Sbjct: 193 ----RGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKH 248
Query: 180 RLVEPVP---------------------------------------DTHLRGITCLDHEN 200
RLV+P P T + TC +HE
Sbjct: 249 RLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEM 308
Query: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
E +MYCVS +C LC GRH H+V L +++ K L L + + E +
Sbjct: 309 ENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEF 368
Query: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
+ +L I QQ++ N +EA L+ +CD LV+ + ++K + K+ + + KL+ + Q+
Sbjct: 369 LVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQIN 428
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATAS--SQVLIPDINFNDA 378
+C L +ST L+ ++KEND + FLQ + + +RV ++ L P ++ A
Sbjct: 429 HCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVS---A 485
Query: 379 FENFALDFSREKKLLEGLDYL----TAPNPPSIREELCTASHDTITVHWISD--DEFSIS 432
+ LD + + LD++ P P ++ E C ++++T+ W +
Sbjct: 486 EFDLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVD 545
Query: 433 SYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPN 492
Y L+ G G + E+ KE +
Sbjct: 546 GYILELDDGAG------------GQFREVYVGKETLC----------------------- 570
Query: 493 IKQNHYTVHGLQSGTRYIFIVKAINQAG-SRNSEPTRLKTNSQP-FKLDPKMTHKKLKIS 550
T+ GL + Y VKA N +G S+ L+T+ F DP H+ + +S
Sbjct: 571 ------TIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILS 624
Query: 551 NDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWY---AIGI 607
ND ++++ S+ GT + G HYWE+ + + A G+
Sbjct: 625 ND------NQTATCSSYDDRVVLGTAAF--------SKGVHYWELHVDRYDNHPDPAFGV 670
Query: 608 AYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKR----------LGVL 657
A S K+ +GK+ +W + NN+ + H R +GVL
Sbjct: 671 ARASVVKDMMLGKDDKAWA--------MYVDNNRSWFMHCNSHTNRTEGGVCKGATVGVL 722
Query: 658 LDYDNNMLSFY 668
LD + + L+F+
Sbjct: 723 LDLNKHTLTFF 733
Score = 51.2 bits (121), Expect = 3e-06
Identities = 18/38 (47%), Positives = 27/38 (71%)
Query: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSS 61
+E EL CP+C LF +P++LPC+H++C CA I V +
Sbjct: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQT 38
>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
Length = 710
Score = 186 bits (473), Expect = 5e-47
Identities = 164/657 (24%), Positives = 262/657 (39%), Gaps = 105/657 (15%)
Query: 76 CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135
CP C + L+ RGL G +N L+ +IDR+Q++ +
Sbjct: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAA---------------------- 165
Query: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGI-- 193
+ CQ CE+ P++A C C+V YCD C HP + P HRLV P R +
Sbjct: 166 -LKCQLCEK-APKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223
Query: 194 ----TCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249
TC DHE E +MYCV +C C G+H H+V +L ++ K L L
Sbjct: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283
Query: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309
L R E + + +L + QQ++ N+ EA L+ +CD L++ + +RK + ++ +
Sbjct: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343
Query: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATA--SSQ 367
KL+ + Q+++C L ++T L+ ++KEND + FLQ + + RV +
Sbjct: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403
Query: 368 VLIPDINFNDAFENFALDFSREKKLLEGLDYL------TAPNPPSIREELCTASHDTITV 421
L P + + + +LD S + + LD++ P P ++ E C +++ T+
Sbjct: 404 TLTPRMTTD---FDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
Query: 422 HWISDDEFSI--SSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRG 479
W ++ Y L+ G G + E+ KE +
Sbjct: 461 SWKQPPLSTVPADGYILELDDGNG------------GQFREVYVGKETMC---------- 498
Query: 480 LYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQP--FK 537
TV GL + Y VKA N+ G T + S+ F
Sbjct: 499 -------------------TVDGLHFNSTYNARVKAFNKTGVSPYSKTLVLQTSEVAWFA 539
Query: 538 LDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVM 597
DP H + +SND L + T + G G G HYWE+ +
Sbjct: 540 FDPGSAHSDIILSNDNLTV-----------TCSSYDDRVVLGKTG---FSKGIHYWELTV 585
Query: 598 GSSTWY---AIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLK-- 652
+ A G+A K+ +GK+ +W N+ HNN K
Sbjct: 586 DRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTEGGITKGA 645
Query: 653 RLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILSGLPAPDF 709
+GVLLD + L+F+ FD L N + + +GLP PDF
Sbjct: 646 TIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLPVPDF 702
>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
sapiens]
Length = 749
Score = 177 bits (449), Expect = 3e-44
Identities = 155/584 (26%), Positives = 255/584 (43%), Gaps = 73/584 (12%)
Query: 197 DHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSE 256
+ E E +++CV+ I A K+ H++H+V LN+ E K + N+ L K+ E
Sbjct: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
Query: 257 LENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLA 316
+EN L ++ VE N E +E++E + Q+ + + E K KL L
Sbjct: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
Query: 317 QQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN 376
Q+ +C + L+ L+ E + E ++ F++ A +A+R+ + + +I+
Sbjct: 290 GQLVSCGENLDTCKELMETIEEMCHE-EKVDFIKDAVAMADRLGKFLKTKTDV--EISAQ 346
Query: 377 DAFENFALDFSREKKLLEGLDYLTAPNPPSIREELC-TASHDTITVHWISDDEFSISSYE 435
FE+ LDFS ++L+ ++ + AP+ P I ++ +A+ ++ V W + ++ SY+
Sbjct: 347 PEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDDTVESYQ 406
Query: 436 LQYTIF------TGQANF---ISKSWCS---------WGLW------------------- 458
L Y T QA F + +++CS + W
Sbjct: 407 LSYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYM 466
Query: 459 ----PEIRKCKEAVSCSR--LAGAPRGLYNSVDSWMIV------PNIKQNHYTVHG---- 502
P I K KE SC L G N VDS+ + P +V G
Sbjct: 467 TAPSPPIIKTKEIRSCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTC 526
Query: 503 -----LQSGTRYIFIVKAINQAG-SRNSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQM 556
LQ G YI V+A+N G S SEP + T F+L+ H L IS DGL
Sbjct: 527 ESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIGSYFRLNKDTCHPWLTISEDGLTA 586
Query: 557 EKDESSLK-KSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKN 615
+ E + +P T C GN+ G HYWEV + Y +G+A+ K
Sbjct: 587 VRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAFADVRKQ 646
Query: 616 EWIGKNASSWVF------SRCNSNFVVRHNNKEMLVDVPPHLKRLGVLLDYDNNMLSFYD 669
E +G N SW SR F+ ++ + VPP K++G+LLDY+++ LSF++
Sbjct: 647 EDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPP--KKIGILLDYEHSKLSFFN 704
Query: 670 PANSLHLHTFDVTFILPVCPTFTIWNKS-LMILSGLPAPDFIDY 712
S HL+TF V P F++ L + +G+ P + +
Sbjct: 705 VDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHVTF 748
>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
Length = 550
Score = 159 bits (403), Expect = 7e-39
Identities = 100/362 (27%), Positives = 168/362 (46%), Gaps = 41/362 (11%)
Query: 76 CPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSE 135
CP C + L+ RGL G +N L+ +IDR+Q++ +
Sbjct: 128 CPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQSKAAA---------------------- 165
Query: 136 RIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGI-- 193
+ CQ CE+ P++A C C+V YCD C HP + P HRLV P R +
Sbjct: 166 -LKCQLCEK-APKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVSRRLSP 223
Query: 194 ----TCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTN 249
TC DHE E +MYCV +C C G+H H+V +L ++ K L L
Sbjct: 224 RKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLSQALNG 283
Query: 250 LVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKV 309
L R E + + +L + QQ++ N+ EA L+ +CD L++ + +RK + ++ +
Sbjct: 284 LSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARVNKEHE 343
Query: 310 MKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATA--SSQ 367
KL+ + Q+++C L ++T L+ ++KEND + FLQ + + RV +
Sbjct: 344 HKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTEDQWGKG 403
Query: 368 VLIPDINFNDAFENFALDFSREKKLLEGLDYL------TAPNPPSIREELCTASHDTITV 421
L P + + + +LD S + + LD++ P P ++ E C +++ T+
Sbjct: 404 TLTPRMTTD---FDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSATL 460
Query: 422 HW 423
W
Sbjct: 461 SW 462
>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
Length = 630
Score = 140 bits (354), Expect = 3e-33
Identities = 161/689 (23%), Positives = 261/689 (37%), Gaps = 93/689 (13%)
Query: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83
L EL+C ICLE F++P+ PC H+ C SC + S + CP CR V
Sbjct: 7 LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS---------PYLCPQCRAV- 56
Query: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143
++ L +N L N++++F +A ++ P R + + ++AC C
Sbjct: 57 ---YQARPQLHKNTVLCNVVEQFLQADLA--REPPADVWTPPARASAPSPNAQVACDHCL 111
Query: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203
++ AVKTC+ C S+C L+ H + F H L PV D R C H N
Sbjct: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQH-NRLR 164
Query: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263
+C + IC +C + H+ ASL+ L+ TL LT + + + +
Sbjct: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222
Query: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323
+ Q V + +L +E E+ ++ + KIKE + K
Sbjct: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILL 282
Query: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN----DAF 379
+ L + E L + D+ FL+ A + ++ V IP++ N
Sbjct: 283 KKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKLIKGI 337
Query: 380 ENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYT 439
+D E K + + L P P S HD + H + +S E
Sbjct: 338 HQSTIDLKNELK--QCIGRLQEPTPSSGD----PGEHDPASTHKSTRPVKKVSKEE---- 387
Query: 440 IFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLA------GAPRGLYNSVDSWM-IVPN 492
+K K+ L GAP L + + +
Sbjct: 388 ----------------------KKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAK 425
Query: 493 IKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISND 552
+H L++ F+ K S P L+ + LD H K+ +S
Sbjct: 426 ATSSHPNSTSLKAKVLETFLAK---------SRPELLEYYIKVI-LDYNTAHNKVALSEC 475
Query: 553 GLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSA 612
E P+RF T C G G HYWEV + + + +GI Y S
Sbjct: 476 YTVASVAEMPQNYRPHPQRF--TYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSM 533
Query: 613 PK---NEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLK--RLGVLLDYDNNMLSF 667
+ +G+N++SW N+ HNN E + P K R+GVLL+ D+ + F
Sbjct: 534 NRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTL---PSTKATRVGVLLNCDHGFVIF 590
Query: 668 YDPANSLHL-HTFDVTFILPVCPTFTIWN 695
+ A+ +HL + F V F + P F +++
Sbjct: 591 FAVADKVHLMYKFRVDFTEALYPAFWVFS 619
>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
Length = 400
Score = 125 bits (314), Expect = 1e-28
Identities = 97/390 (24%), Positives = 178/390 (45%), Gaps = 48/390 (12%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSSCSSGESIEPITA-----F 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA+ + +S +S T F
Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+ E+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR--LVEPVPDTHLR- 191
CE+ C++CEV C C K F +H+ V P+P + R
Sbjct: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170
Query: 192 ---GITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLT 248
+T L + C + C+L L +AS N + + L +
Sbjct: 171 KKQDLTLLP------RLECSGTNTTYCSL-DLPSSSDPPILASQNTKI--IDSELSDGIA 221
Query: 249 NLVKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETK 308
LV N ++ + ++ ++CQ +E N+ + L + + L ++++RK + + +
Sbjct: 222 MLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQ 281
Query: 309 VMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQV 368
KL+++ + LE S+ L+ A ++E A +LQ AK + +V +
Sbjct: 282 EEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELA 341
Query: 369 LIPDINFNDAFENFALDFSREKKLLEGLDY 398
P+ + ++ E F + ++L +D+
Sbjct: 342 GRPEPGY-ESMEQFTVRVEHVAEMLRTIDF 370
>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
Length = 452
Score = 124 bits (311), Expect = 3e-28
Identities = 92/384 (23%), Positives = 167/384 (43%), Gaps = 80/384 (20%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS-----CSSGESIEPITAF 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA I +S G ++ F
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES-TRPEKKSDQ-------------- 121
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGIT 194
CE+ C+ CEV C C K F +H+ + P TH+
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV---- 164
Query: 195 CLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRN 254
F++ K L + LV N
Sbjct: 165 -----------------------------------------FQRQKSELSDGIAILVGSN 183
Query: 255 SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRK 314
++ +++L C+ +E + +L E+ D L I+++RK + I T+ KL
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243
Query: 315 LAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDIN 374
+ + LE + L+ + E + A FLQ+AK + ++++ A+ + Q+ +
Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHG 303
Query: 375 FNDAFENFALDFSREKKLLEGLDY 398
+ + +F ++ +RE+K++ +D+
Sbjct: 304 YEN-MNHFTVNLNREEKIIREIDF 326
>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
Length = 548
Score = 124 bits (311), Expect = 3e-28
Identities = 92/384 (23%), Positives = 167/384 (43%), Gaps = 80/384 (20%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS-----CSSGESIEPITAF 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA I +S G ++ F
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES-TRPEKKSDQ-------------- 121
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGIT 194
CE+ C+ CEV C C K F +H+ + P TH+
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV---- 164
Query: 195 CLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRN 254
F++ K L + LV N
Sbjct: 165 -----------------------------------------FQRQKSELSDGIAILVGSN 183
Query: 255 SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRK 314
++ +++L C+ +E + +L E+ D L I+++RK + I T+ KL
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243
Query: 315 LAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDIN 374
+ + LE + L+ + E + A FLQ+AK + ++++ A+ + Q+ +
Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHG 303
Query: 375 FNDAFENFALDFSREKKLLEGLDY 398
+ + +F ++ +RE+K++ +D+
Sbjct: 304 YEN-MNHFTVNLNREEKIIREIDF 326
>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
Length = 540
Score = 124 bits (311), Expect = 3e-28
Identities = 92/384 (23%), Positives = 167/384 (43%), Gaps = 80/384 (20%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS-----CSSGESIEPITAF 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA I +S G ++ F
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES-TRPEKKSDQ-------------- 121
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGIT 194
CE+ C+ CEV C C K F +H+ + P TH+
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV---- 164
Query: 195 CLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRN 254
F++ K L + LV N
Sbjct: 165 -----------------------------------------FQRQKSELSDGIAILVGSN 183
Query: 255 SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRK 314
++ +++L C+ +E + +L E+ D L I+++RK + I T+ KL
Sbjct: 184 DRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKLEH 243
Query: 315 LAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDIN 374
+ + LE + L+ + E + A FLQ+AK + ++++ A+ + Q+ +
Sbjct: 244 VRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIEHG 303
Query: 375 FNDAFENFALDFSREKKLLEGLDY 398
+ + +F ++ +RE+K++ +D+
Sbjct: 304 YEN-MNHFTVNLNREEKIIREIDF 326
>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
Length = 353
Score = 113 bits (282), Expect = 7e-25
Identities = 96/396 (24%), Positives = 164/396 (41%), Gaps = 79/396 (19%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS----CSSGESIEPITA-F 74
ME LE +L CPICLE+F P+ +LPC H+LC CA+ I ++ S G S+ F
Sbjct: 14 MENLEKQLICPICLEMFTKPVVILPCQHNLCRKCANDIFQAANPYWTSRGSSVSMSGGRF 73
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CPTCR+ + ++ G+ GL+RN+ ++NIID +++ S P
Sbjct: 74 RCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRP-------------------L 114
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGIT 194
++ + C++ C+TCEV C C K F H+ E
Sbjct: 115 QKGSHPMCKEHEDEKINIYCLTCEVPTCSMC--------KVFGIHKACE----------- 155
Query: 195 CLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRN 254
VA L F+ K L ++ LV N
Sbjct: 156 ----------------------------------VAPLQSVFQGQKTELNNCISMLVAGN 181
Query: 255 SELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRK 314
++ + +L + + N+ + +L ++ D L I+ ++K + +I + + KL
Sbjct: 182 DRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKLSF 241
Query: 315 LAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDIN 374
+ + ++ L++ST L+ A L E A FL +AK + + + A+ Q+ +
Sbjct: 242 IEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTEQG 301
Query: 375 FNDAFENFALDFSREKKLLEGLDYLTAPNPPSIREE 410
F + + F LD L +D+ T EE
Sbjct: 302 FEN-MDFFTLDLEHIADALRAIDFGTDEEEEEFIEE 336
>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
Length = 358
Score = 108 bits (270), Expect = 2e-23
Identities = 97/362 (26%), Positives = 164/362 (45%), Gaps = 60/362 (16%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSSCSSGESIEPITA-----F 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA+ + +S +S T F
Sbjct: 17 MDNLEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVFQASNPLWQSRGSTTVSSGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+ E+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES----SRPLHSKAEQHL-------- 124
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHR--LVEPVPDTHLR- 191
CE+ C++CEV C C K F +H+ V P+P + R
Sbjct: 125 ------MCEEHEEEKINIYCLSCEVPTCSLC--------KVFGAHKDCEVAPLPTIYKRQ 170
Query: 192 ------GITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEM 245
GI L N++V ++ +C+ + + Q LN RFE L LE
Sbjct: 171 KSELSDGIAMLVAGNDRVQAVITQMEE----VCQTIEDNSRRQKQLLNQRFESLCAVLEE 226
Query: 246 NLTNLV-----KRNSELENQMAKLIQICQQVEVNTAMHEAKL--MEECDELVEIIQQRKQ 298
L+ ++ +L+ + Q +E ++ + E+ + MEE ++ +QQ K+
Sbjct: 227 RKGELLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEE-PQMALYLQQAKE 285
Query: 299 MIAVKIKETKVMKLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAER 358
+ I + M +LA + + +E+ TV + +L+ D F A E
Sbjct: 286 L----INKVGAMSKVELAGRPEPGYESMEQFTVRVEHVAEMLRTID---FQPGASGEEEE 338
Query: 359 VA 360
VA
Sbjct: 339 VA 340
Score = 95.5 bits (236), Expect = 2e-19
Identities = 51/206 (24%), Positives = 105/206 (50%), Gaps = 1/206 (0%)
Query: 193 ITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVK 252
+ C +HE EK+N+YC+S + C+LCK+ G H+D +VA L +++ K L + LV
Sbjct: 124 LMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDGIAMLVA 183
Query: 253 RNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKL 312
N ++ + ++ ++CQ +E N+ + L + + L ++++RK + + + KL
Sbjct: 184 GNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKL 243
Query: 313 RKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPD 372
+++ + LE S+ L+ A ++E A +LQ AK + +V + P+
Sbjct: 244 QRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPE 303
Query: 373 INFNDAFENFALDFSREKKLLEGLDY 398
+ ++ E F + ++L +D+
Sbjct: 304 PGY-ESMEQFTVRVEHVAEMLRTIDF 328
>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
Length = 551
Score = 105 bits (263), Expect = 1e-22
Identities = 87/380 (22%), Positives = 159/380 (41%), Gaps = 48/380 (12%)
Query: 25 ESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGES-IEPITAFQCPTCRYVI 83
E EL CPICL +F +P+ LPC H+ C C GE+ + +CP C
Sbjct: 10 EEELICPICLHVFVEPVQLPCKHNFCRGCI----------GEAWAKDSGLVRCPECNQA- 58
Query: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143
+ GL++N+ L NI+++F V P + + C FC
Sbjct: 59 ---YNQKPGLEKNLKLTNIVEKFNALHVEKPPA-------------------ALHCVFCR 96
Query: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203
+ PP A K C+ CE C ++ H LVE +R +C H ++
Sbjct: 97 RGPPLPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEA---DDVRAWSCPQHNAYRL 153
Query: 204 NMYCVSDDQLICA-LCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMA 262
+C ++ +C C G H+ H V + R ++++ L L +R ++E+Q+
Sbjct: 154 -YHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLY 212
Query: 263 KLIQICQQVE--VNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
KL + VE VN E +L E +L +++ + + + + + + A Q
Sbjct: 213 KLESDKRLVEEKVNQLKEEVRLQYE--KLHQLLDEDLRQTVEVLDKAQAKFCSENAAQAL 270
Query: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNI---AERVAMATAS--SQVLIPDINF 375
+ + ++ + L+ + + + + F+++ K++ +R T+S S I +N
Sbjct: 271 HLGERMQEAKKLLGSLQLLFDKTEDVSFMKNTKSVKILMDRTQTCTSSSLSPTKIGHLNS 330
Query: 376 NDAFENFALDFSREKKLLEG 395
A + +K+LEG
Sbjct: 331 KLFLNEVAKKEKQLRKMLEG 350
>gi|28195390 tripartite motif-containing 42 [Homo sapiens]
Length = 723
Score = 103 bits (258), Expect = 4e-22
Identities = 95/411 (23%), Positives = 167/411 (40%), Gaps = 37/411 (9%)
Query: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83
L + L CP+C L +LPC HSLC C ++ E E CP C
Sbjct: 140 LVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQ----KHAEVTENFFILICPVCDRSH 195
Query: 84 SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143
+ + L N + R+ + + + R +R SS I CQ C
Sbjct: 196 CMPYSNKMQLPENYLHGRLTKRYMQ-----EHGYLKWRFDR--------SSGPILCQVCR 242
Query: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203
R A K CITC ++ C+ CL+A H + H V+ + I C+ H + ++
Sbjct: 243 N--RRIAYKRCITCRLNLCNDCLKAFH-SDVAMQDHVFVDTSAEEQDEKI-CIHHPSSRI 298
Query: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263
YC +D++L+C CK H H SL D + +L + E++N + +
Sbjct: 299 IEYCRNDNKLLCTFCKF-SFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLME 357
Query: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323
+ + + ++ +L I+Q+++++I +I+ +V + +++ + V
Sbjct: 358 FNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTT 417
Query: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDAFENFA 383
+ LI ++ LKE Q FLQSAK + +++ ++ P + + +
Sbjct: 418 MKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLH-SINYVP 476
Query: 384 LDF------------SREKKLLEGLDYLTAPNPPSIREELCTASHDTITVH 422
LDF + KK+ D L +P P + E A T + H
Sbjct: 477 LDFVELSSAIHELFPTGPKKVRSSGDSLPSPYP--VHSETMIARKVTFSTH 525
>gi|34878852 tripartite motif-containing 55 isoform 4 [Homo sapiens]
Length = 241
Score = 89.0 bits (219), Expect = 1e-17
Identities = 55/176 (31%), Positives = 85/176 (48%), Gaps = 34/176 (19%)
Query: 21 METLESELTCPICLELFEDPL-LLPCAHSLCFSCAHRILVSS-----CSSGESIEPITAF 74
M+ LE +L CPICLE+F P+ +LPC H+LC CA I +S G ++ F
Sbjct: 17 MDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTMASGGRF 76
Query: 75 QCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSS 134
+CP+CR+ + L+ G+ GL+RN+ ++NIID +++ S + P S+
Sbjct: 77 RCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQES-TRPEKKSDQ-------------- 121
Query: 135 ERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHL 190
CE+ C+ CEV C C K F +H+ + P TH+
Sbjct: 122 -----PMCEEHEEERINIYCLNCEVPTCSLC--------KVFGAHKDCQVAPLTHV 164
>gi|15208643 ADP-ribosylation factor domain protein 1 isoform gamma
[Homo sapiens]
Length = 546
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/255 (24%), Positives = 110/255 (43%), Gaps = 34/255 (13%)
Query: 28 LTCPICLELF-----EDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYV 82
L C +C ++F + P LL C H++C C R+ + A +CP R V
Sbjct: 29 LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHG----------RAIRCPFDRQV 78
Query: 83 ISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFC 142
L G+ GLK+N L +++R Q + + ES +S E I C
Sbjct: 79 TDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEES---------IGISGESII--RC 127
Query: 143 EQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEK 202
++D A C C C C + TH + K HR V P+ D C H+
Sbjct: 128 DEDEAHLASVYCTVCATHLCSECSQVTH-STKTLAKHRRV-PLADKPHEKTMCSQHQVHA 185
Query: 203 VNMYCVSD----DQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKR-NSEL 257
+ C+ + L+C +CK G+H+ H+ + L +++ ++ +++ + ++ E+
Sbjct: 186 IEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASI-LDMAHCIRTFTEEI 244
Query: 258 ENQMAKLIQICQQVE 272
+ KL+ I Q +E
Sbjct: 245 SDYSRKLVGIVQHIE 259
>gi|15208641 ADP-ribosylation factor domain protein 1 isoform beta
[Homo sapiens]
Length = 569
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/255 (24%), Positives = 110/255 (43%), Gaps = 34/255 (13%)
Query: 28 LTCPICLELF-----EDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYV 82
L C +C ++F + P LL C H++C C R+ + A +CP R V
Sbjct: 29 LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHG----------RAIRCPFDRQV 78
Query: 83 ISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFC 142
L G+ GLK+N L +++R Q + + ES +S E I C
Sbjct: 79 TDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEES---------IGISGESII--RC 127
Query: 143 EQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEK 202
++D A C C C C + TH + K HR V P+ D C H+
Sbjct: 128 DEDEAHLASVYCTVCATHLCSECSQVTH-STKTLAKHRRV-PLADKPHEKTMCSQHQVHA 185
Query: 203 VNMYCVSD----DQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKR-NSEL 257
+ C+ + L+C +CK G+H+ H+ + L +++ ++ +++ + ++ E+
Sbjct: 186 IEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASI-LDMAHCIRTFTEEI 244
Query: 258 ENQMAKLIQICQQVE 272
+ KL+ I Q +E
Sbjct: 245 SDYSRKLVGIVQHIE 259
>gi|4502197 ADP-ribosylation factor domain protein 1 isoform alpha
[Homo sapiens]
Length = 574
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/255 (24%), Positives = 110/255 (43%), Gaps = 34/255 (13%)
Query: 28 LTCPICLELF-----EDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYV 82
L C +C ++F + P LL C H++C C R+ + A +CP R V
Sbjct: 29 LECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHG----------RAIRCPFDRQV 78
Query: 83 ISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFC 142
L G+ GLK+N L +++R Q + + ES +S E I C
Sbjct: 79 TDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEES---------IGISGESII--RC 127
Query: 143 EQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEK 202
++D A C C C C + TH + K HR V P+ D C H+
Sbjct: 128 DEDEAHLASVYCTVCATHLCSECSQVTH-STKTLAKHRRV-PLADKPHEKTMCSQHQVHA 185
Query: 203 VNMYCVSD----DQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKR-NSEL 257
+ C+ + L+C +CK G+H+ H+ + L +++ ++ +++ + ++ E+
Sbjct: 186 IEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASI-LDMAHCIRTFTEEI 244
Query: 258 ENQMAKLIQICQQVE 272
+ KL+ I Q +E
Sbjct: 245 SDYSRKLVGIVQHIE 259
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 82.0 bits (201), Expect = 2e-15
Identities = 89/360 (24%), Positives = 148/360 (41%), Gaps = 72/360 (20%)
Query: 29 TCPICLELFE-----DPLLLPCAHSLCFSCAHR------ILVSSCSSGESIEPITAFQCP 77
TC +C + + +P LLPC HS C C + + S+G+ I+ + +CP
Sbjct: 124 TCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGD-IQQVGVIRCP 182
Query: 78 TCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERI 137
CR R + L + + F K + P+S E SE++
Sbjct: 183 VCRQEC-----------RQIDL--VDNYFVKDTSEAPSSSDEK-------------SEQV 216
Query: 138 ACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLV-------EPVPDTHL 190
C CE + AV C+ C C C+ A H K FT L+ E V +
Sbjct: 217 -CTSCEDNA--SAVGFCVECGEWLCKTCIEA-HQRVK-FTKDHLIRKKEDVSESVGASGQ 271
Query: 191 RGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNL 250
R + C H+ E++ ++C + D+L C C+L+ H++H+ L + F+ K
Sbjct: 272 RPVFCPVHKQEQLKLFCETCDRLTCRDCQLL-EHKEHRYQFLEEAFQNQK---------- 320
Query: 251 VKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVM 310
+EN +AKL++ V + ++ E + + Q+ K I I E
Sbjct: 321 ----GAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEIN-K 375
Query: 311 KLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLI 370
K + L QQ+ N + ER L+ Q I + Q + + + N A+A+ SS L+
Sbjct: 376 KGKSLLQQLENVTK--ERQMKLLQQQNDITGLSRQVKHVMNFTN----WAIASGSSTALL 429
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 82.0 bits (201), Expect = 2e-15
Identities = 89/360 (24%), Positives = 148/360 (41%), Gaps = 72/360 (20%)
Query: 29 TCPICLELFE-----DPLLLPCAHSLCFSCAHR------ILVSSCSSGESIEPITAFQCP 77
TC +C + + +P LLPC HS C C + + S+G+ I+ + +CP
Sbjct: 124 TCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGD-IQQVGVIRCP 182
Query: 78 TCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERI 137
CR R + L + + F K + P+S E SE++
Sbjct: 183 VCRQEC-----------RQIDL--VDNYFVKDTSEAPSSSDEK-------------SEQV 216
Query: 138 ACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLV-------EPVPDTHL 190
C CE + AV C+ C C C+ A H K FT L+ E V +
Sbjct: 217 -CTSCEDNA--SAVGFCVECGEWLCKTCIEA-HQRVK-FTKDHLIRKKEDVSESVGASGQ 271
Query: 191 RGITCLDHENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNL 250
R + C H+ E++ ++C + D+L C C+L+ H++H+ L + F+ K
Sbjct: 272 RPVFCPVHKQEQLKLFCETCDRLTCRDCQLL-EHKEHRYQFLEEAFQNQK---------- 320
Query: 251 VKRNSELENQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVM 310
+EN +AKL++ V + ++ E + + Q+ K I I E
Sbjct: 321 ----GAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEIN-K 375
Query: 311 KLRKLAQQVANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLI 370
K + L QQ+ N + ER L+ Q I + Q + + + N A+A+ SS L+
Sbjct: 376 KGKSLLQQLENVTK--ERQMKLLQQQNDITGLSRQVKHVMNFTN----WAIASGSSTALL 429
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 81.6 bits (200), Expect = 2e-15
Identities = 58/239 (24%), Positives = 119/239 (49%), Gaps = 4/239 (1%)
Query: 199 ENEKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELE 258
+ +++ YC + I A K+ G H+DH+V++L+ +K L L NL +++ +E
Sbjct: 3505 KKSQIDTYCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQEKSLRIE 3564
Query: 259 NQMAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQ 318
++++ +E N + +E +L E+ +E+++ + + A +E K K+ L +Q
Sbjct: 3565 AFVSEIESFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKMEFLHEQ 3624
Query: 319 VANCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFNDA 378
+ + Q ++ + + +E D+A FL S + I ER+ A S+ L
Sbjct: 3625 MVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINERLLSAMESTASLEKMPAAFSL 3684
Query: 379 FENFALDFSREKKLLEGLDYLTAPNPPSIR-EELCTASHDTITVHWISDDEFSISSYEL 436
FE++ +R ++L+ + P PP + +E +A+ TI V+W + E I S+++
Sbjct: 3685 FEHYDDSSARSDQMLK---QVAVPQPPRLEPQEPNSATSTTIAVYWSMNKEDVIDSFQV 3740
Score = 71.2 bits (173), Expect = 3e-12
Identities = 86/367 (23%), Positives = 132/367 (35%), Gaps = 56/367 (15%)
Query: 350 QSAKNIAERVAMATASSQVLIPDINFNDAFENF--ALDFSREKKLLEGLDYLTAPNPPSI 407
Q + E + S + D+ + ++ + A++F+ E + TAP+ P I
Sbjct: 3750 QEVNELVEEYRLTVKESYCIFEDLEPDRCYQVWVMAVNFTGCSLPSERAIFRTAPSTPVI 3809
Query: 408 REELCTASHDTITVHWISDDEFSISSYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEA 467
R E CT +T T+ W + +Y L+Y
Sbjct: 3810 RAEDCTVCWNTATIRWRPTTPEATETYTLEY----------------------------- 3840
Query: 468 VSCSRLAGAPRGLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAG-SRNSEP 526
C + + GL + IK V+ LQ Y F V+AIN G S SE
Sbjct: 3841 --CRQHSPEGEGLRS-------FSGIKGLQLKVN-LQPNDNYFFYVRAINAFGTSEQSEA 3890
Query: 527 TRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFI 586
+ T F L + H L IS+ G + E R T G
Sbjct: 3891 ALISTRGTRFLLLRETAHPALHISSSGTVISFGE----------RRRLTEIPSVLGEELP 3940
Query: 587 DSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIGKNASSWVFSRCN--SNFVVRHNNKEML 644
G HYWE + Y +GI SA + +G+ +SW + C+ + ++
Sbjct: 3941 SCGQHYWETTVTDCPAYRLGICSSSAVQAGALGQGETSW-YMHCSEPQRYTFFYSGIVSD 3999
Query: 645 VDVPPHLKRLGVLLDYDNNMLSFYDPANSLHLHTFDVTFILPVCPTFTIWNKSLMILS-G 703
V V R+G+LLDY+N L F + + L F V P F + L G
Sbjct: 4000 VHVTERPARVGILLDYNNQRLIFINAESEQLLFIIRHRFNEGVHPAFALEKPGKCTLHLG 4059
Query: 704 LPAPDFI 710
+ PD +
Sbjct: 4060 IEPPDSV 4066
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,175,602
Number of Sequences: 37866
Number of extensions: 1321006
Number of successful extensions: 5192
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 239
Number of HSP's successfully gapped in prelim test: 218
Number of HSP's that attempted gapping in prelim test: 3990
Number of HSP's gapped (non-prelim): 1176
length of query: 735
length of database: 18,247,518
effective HSP length: 110
effective length of query: 625
effective length of database: 14,082,258
effective search space: 8801411250
effective search space used: 8801411250
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.