BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo sapiens] (1236 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo... 2437 0.0 gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo... 2141 0.0 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 57 1e-07 gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 49 4e-05 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 48 5e-05 gi|221219020 NYD-SP11 protein [Homo sapiens] 48 7e-05 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 48 7e-05 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 48 7e-05 gi|17975763 myelin transcription factor 1 [Homo sapiens] 47 9e-05 gi|148746195 trichohyalin [Homo sapiens] 47 9e-05 gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 47 1e-04 gi|156104891 general transcription factor IIF, polypeptide 1, 74... 47 1e-04 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 46 2e-04 gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 46 2e-04 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 46 3e-04 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 46 3e-04 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 46 3e-04 gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 46 3e-04 gi|21361639 DIPB protein [Homo sapiens] 45 3e-04 gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 45 4e-04 gi|42476169 Paf1, RNA polymerase II associated factor, homolog [... 45 6e-04 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 44 7e-04 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 44 7e-04 gi|5453567 craniofacial development protein 1 [Homo sapiens] 44 7e-04 gi|28274705 family with sequence similarity 9, member A [Homo sa... 44 7e-04 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 0.001 gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 44 0.001 gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 44 0.001 gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 44 0.001 gi|27597090 suppressor of Ty 6 homolog [Homo sapiens] 44 0.001 >gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo sapiens] Length = 1236 Score = 2437 bits (6316), Expect = 0.0 Identities = 1236/1236 (100%), Positives = 1236/1236 (100%) Query: 1 MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN 60 MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN Sbjct: 1 MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN 60 Query: 61 ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA 120 ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA Sbjct: 61 ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA 120 Query: 121 HKEICAVLAAVTEVIRSQGGKETETEYFAALVLSCLATLLRKQDLEAWGYPVTLQVYHGL 180 HKEICAVLAAVTEVIRSQGGKETETEYFAALVLSCLATLLRKQDLEAWGYPVTLQVYHGL Sbjct: 121 HKEICAVLAAVTEVIRSQGGKETETEYFAALVLSCLATLLRKQDLEAWGYPVTLQVYHGL 180 Query: 181 LSFTVHPKPKIRKAAQHGVCSVLKGSEFMFEKAPAHHPAAISTAKFCIQEIEKSGGSKEA 240 LSFTVHPKPKIRKAAQHGVCSVLKGSEFMFEKAPAHHPAAISTAKFCIQEIEKSGGSKEA Sbjct: 181 LSFTVHPKPKIRKAAQHGVCSVLKGSEFMFEKAPAHHPAAISTAKFCIQEIEKSGGSKEA 240 Query: 241 TTTLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLSHVLVTACAMQAFHSLFHARPGLST 300 TTTLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLSHVLVTACAMQAFHSLFHARPGLST Sbjct: 241 TTTLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLSHVLVTACAMQAFHSLFHARPGLST 300 Query: 301 LSAELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQWDLGLGHLPRFFGTAV 360 LSAELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQWDLGLGHLPRFFGTAV Sbjct: 301 LSAELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQWDLGLGHLPRFFGTAV 360 Query: 361 TCLLSPHSQVLTAATQSLKEILKECVAPHMADIGSVTSSASGPAQSVAKMFRAVEEGLTY 420 TCLLSPHSQVLTAATQSLKEILKECVAPHMADIGSVTSSASGPAQSVAKMFRAVEEGLTY Sbjct: 361 TCLLSPHSQVLTAATQSLKEILKECVAPHMADIGSVTSSASGPAQSVAKMFRAVEEGLTY 420 Query: 421 KFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTS 480 KFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTS Sbjct: 421 KFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTS 480 Query: 481 MGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAM 540 MGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAM Sbjct: 481 MGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAM 540 Query: 541 DLAQAGSTVESKIYDTLQWQMWTLLPGFCTRPTDVAISFKGLARTLGMAISERPDLRVTV 600 DLAQAGSTVESKIYDTLQWQMWTLLPGFCTRPTDVAISFKGLARTLGMAISERPDLRVTV Sbjct: 541 DLAQAGSTVESKIYDTLQWQMWTLLPGFCTRPTDVAISFKGLARTLGMAISERPDLRVTV 600 Query: 601 CQALRTLITKGCQAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIRTYL 660 CQALRTLITKGCQAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIRTYL Sbjct: 601 CQALRTLITKGCQAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIRTYL 660 Query: 661 TITDTQLVNSLLEKASEKVLDPASSDFTRLSVLDLVVALAPCADEAAISKLYSTIRPYLE 720 TITDTQLVNSLLEKASEKVLDPASSDFTRLSVLDLVVALAPCADEAAISKLYSTIRPYLE Sbjct: 661 TITDTQLVNSLLEKASEKVLDPASSDFTRLSVLDLVVALAPCADEAAISKLYSTIRPYLE 720 Query: 721 SKAHGVQKKAYRVLEEVCASPQGPGALFVQSHLEDLKKTLLDSLRSTSSPAKRPRLKCLL 780 SKAHGVQKKAYRVLEEVCASPQGPGALFVQSHLEDLKKTLLDSLRSTSSPAKRPRLKCLL Sbjct: 721 SKAHGVQKKAYRVLEEVCASPQGPGALFVQSHLEDLKKTLLDSLRSTSSPAKRPRLKCLL 780 Query: 781 HIVRKLSAEHKEFITALIPEVILCTKEVSVGARKNAFALLVEMGHAFLRFGSNQEEALQC 840 HIVRKLSAEHKEFITALIPEVILCTKEVSVGARKNAFALLVEMGHAFLRFGSNQEEALQC Sbjct: 781 HIVRKLSAEHKEFITALIPEVILCTKEVSVGARKNAFALLVEMGHAFLRFGSNQEEALQC 840 Query: 841 YLVLIYPGLVGAVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKS 900 YLVLIYPGLVGAVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKS Sbjct: 841 YLVLIYPGLVGAVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKS 900 Query: 901 ALGFIKVAVTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVK 960 ALGFIKVAVTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVK Sbjct: 901 ALGFIKVAVTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVK 960 Query: 961 RLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSE 1020 RLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSE Sbjct: 961 RLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSE 1020 Query: 1021 DEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK 1080 DEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK Sbjct: 1021 DEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK 1080 Query: 1081 KDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEA 1140 KDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEA Sbjct: 1081 KDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEA 1140 Query: 1141 EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKL 1200 EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKL Sbjct: 1141 EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKL 1200 Query: 1201 NRRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRRP 1236 NRRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRRP Sbjct: 1201 NRRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRRP 1236 >gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo sapiens] Length = 1297 Score = 2141 bits (5548), Expect = 0.0 Identities = 1085/1085 (100%), Positives = 1085/1085 (100%) Query: 152 VLSCLATLLRKQDLEAWGYPVTLQVYHGLLSFTVHPKPKIRKAAQHGVCSVLKGSEFMFE 211 VLSCLATLLRKQDLEAWGYPVTLQVYHGLLSFTVHPKPKIRKAAQHGVCSVLKGSEFMFE Sbjct: 213 VLSCLATLLRKQDLEAWGYPVTLQVYHGLLSFTVHPKPKIRKAAQHGVCSVLKGSEFMFE 272 Query: 212 KAPAHHPAAISTAKFCIQEIEKSGGSKEATTTLHMLTLLKDLLPCFPEGLVKSCSETLLR 271 KAPAHHPAAISTAKFCIQEIEKSGGSKEATTTLHMLTLLKDLLPCFPEGLVKSCSETLLR Sbjct: 273 KAPAHHPAAISTAKFCIQEIEKSGGSKEATTTLHMLTLLKDLLPCFPEGLVKSCSETLLR 332 Query: 272 VMTLSHVLVTACAMQAFHSLFHARPGLSTLSAELNAQIITALYDYVPSENDLQPLLAWLK 331 VMTLSHVLVTACAMQAFHSLFHARPGLSTLSAELNAQIITALYDYVPSENDLQPLLAWLK Sbjct: 333 VMTLSHVLVTACAMQAFHSLFHARPGLSTLSAELNAQIITALYDYVPSENDLQPLLAWLK 392 Query: 332 VMEKAHINLVRLQWDLGLGHLPRFFGTAVTCLLSPHSQVLTAATQSLKEILKECVAPHMA 391 VMEKAHINLVRLQWDLGLGHLPRFFGTAVTCLLSPHSQVLTAATQSLKEILKECVAPHMA Sbjct: 393 VMEKAHINLVRLQWDLGLGHLPRFFGTAVTCLLSPHSQVLTAATQSLKEILKECVAPHMA 452 Query: 392 DIGSVTSSASGPAQSVAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKC 451 DIGSVTSSASGPAQSVAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKC Sbjct: 453 DIGSVTSSASGPAQSVAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKC 512 Query: 452 LQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPV 511 LQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPV Sbjct: 513 LQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPV 572 Query: 512 IRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFCTR 571 IRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFCTR Sbjct: 573 IRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFCTR 632 Query: 572 PTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITKGCQAEADRAEVSRFAKNFLPI 631 PTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITKGCQAEADRAEVSRFAKNFLPI Sbjct: 633 PTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITKGCQAEADRAEVSRFAKNFLPI 692 Query: 632 LFNLYGQPVAAGDTPAPRRAVLETIRTYLTITDTQLVNSLLEKASEKVLDPASSDFTRLS 691 LFNLYGQPVAAGDTPAPRRAVLETIRTYLTITDTQLVNSLLEKASEKVLDPASSDFTRLS Sbjct: 693 LFNLYGQPVAAGDTPAPRRAVLETIRTYLTITDTQLVNSLLEKASEKVLDPASSDFTRLS 752 Query: 692 VLDLVVALAPCADEAAISKLYSTIRPYLESKAHGVQKKAYRVLEEVCASPQGPGALFVQS 751 VLDLVVALAPCADEAAISKLYSTIRPYLESKAHGVQKKAYRVLEEVCASPQGPGALFVQS Sbjct: 753 VLDLVVALAPCADEAAISKLYSTIRPYLESKAHGVQKKAYRVLEEVCASPQGPGALFVQS 812 Query: 752 HLEDLKKTLLDSLRSTSSPAKRPRLKCLLHIVRKLSAEHKEFITALIPEVILCTKEVSVG 811 HLEDLKKTLLDSLRSTSSPAKRPRLKCLLHIVRKLSAEHKEFITALIPEVILCTKEVSVG Sbjct: 813 HLEDLKKTLLDSLRSTSSPAKRPRLKCLLHIVRKLSAEHKEFITALIPEVILCTKEVSVG 872 Query: 812 ARKNAFALLVEMGHAFLRFGSNQEEALQCYLVLIYPGLVGAVTMVSCSILALTHLLFEFK 871 ARKNAFALLVEMGHAFLRFGSNQEEALQCYLVLIYPGLVGAVTMVSCSILALTHLLFEFK Sbjct: 873 ARKNAFALLVEMGHAFLRFGSNQEEALQCYLVLIYPGLVGAVTMVSCSILALTHLLFEFK 932 Query: 872 GLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQLVMEAIGKL 931 GLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQLVMEAIGKL Sbjct: 933 GLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQLVMEAIGKL 992 Query: 932 SDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAA 991 SDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAA Sbjct: 993 SDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAA 1052 Query: 992 VEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG 1051 VEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG Sbjct: 1053 VEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG 1112 Query: 1052 GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK 1111 GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK Sbjct: 1113 GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK 1172 Query: 1112 GEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAE 1171 GEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAE Sbjct: 1173 GEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAE 1232 Query: 1172 YKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARRGSQVGHKNRR 1231 YKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARRGSQVGHKNRR Sbjct: 1233 YKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARRGSQVGHKNRR 1292 Query: 1232 KDRRP 1236 KDRRP Sbjct: 1293 KDRRP 1297 Score = 301 bits (770), Expect = 3e-81 Identities = 155/174 (89%), Positives = 161/174 (92%), Gaps = 1/174 (0%) Query: 1 MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN 60 MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN Sbjct: 1 MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN 60 Query: 61 ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA 120 ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA Sbjct: 61 ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA 120 Query: 121 HKEICAVLAAVTEVIRSQGGKETETEYFAALVLSCLATLLRKQDLEAWGYPVTL 174 HKEICAVLAAVTEVIRSQGGKETETEYFAAL ++ + + + L A Y + L Sbjct: 121 HKEICAVLAAVTEVIRSQGGKETETEYFAAL-MTTMEAVESPESLAAVAYLLNL 173 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 57.0 bits (136), Expect = 1e-07 Identities = 66/243 (27%), Positives = 103/243 (42%), Gaps = 20/243 (8%) Query: 993 EEEEEEEEEEEPAQGKGDSI-EEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG 1051 EEE E E EEE +GKG+ EE + E+EE E E G+ + + EG Sbjct: 905 EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG 964 Query: 1052 GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGA- 1110 G+E + + + + G G G +++ + +G EE +G EEEEG Sbjct: 965 EGEEEGEG-EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEG--EEEGEGEGEEEEEGEV 1021 Query: 1111 -------KGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVA 1163 +GE E + E+ +K + + + EEE E +YQ G Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE-----EE 1076 Query: 1164 KKAMPGAEY-KAKKAKGDVKKKGRPDPYAYIPLNRSKLN-RRKKMKLQGQFKGLVKAARR 1221 + G EY K K KG V K G+ Y + ++ N + ++ K+ Q K L+K Sbjct: 1077 NERQDGEEYKKVSKIKGSV-KYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKNGPS 1135 Query: 1222 GSQ 1224 GS+ Sbjct: 1136 GSK 1138 Score = 52.4 bits (124), Expect = 3e-06 Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 18/172 (10%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034 R+ + +R++ + + EE E EEEE GD EE + E +E+ E EE + Sbjct: 715 REQGHQKERNQEMEEGGEEEHGEGEEEE------GDREEEEEKEGEGKEEGEGEEVEGER 768 Query: 1035 EQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLI 1094 E+ + R++ KE G+E + Q + GRG +K+ G +V G + Sbjct: 769 EKEEGERKKEERAGKEEKGEE-------EGDQGEGEEEETEGRGEEKEEGGEVEG-GEV- 819 Query: 1095 IREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELE 1146 EE G + EEEE +GE+EE + E+ ++ + K ++E EE E E Sbjct: 820 --EEGKGEREEEEEEGEGEEEE-GEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868 Score = 49.3 bits (116), Expect = 2e-05 Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 17/122 (13%) Query: 994 EEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGG 1053 EE + E EEE +G+G+ EE + E+ E EEE +G+E+ + EG G Sbjct: 820 EEGKGEREEEEEEGEGEE-EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG 878 Query: 1054 DEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGE 1113 +E + G G G ++ G +G EE +G EEE KGE Sbjct: 879 EE----------------EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE 922 Query: 1114 DE 1115 +E Sbjct: 923 EE 924 Score = 46.6 bits (109), Expect = 1e-04 Identities = 48/167 (28%), Positives = 68/167 (40%), Gaps = 19/167 (11%) Query: 993 EEEEEEEE-EEEPAQGKGDSIEEILADSEDEEDNEEE-ERSRGKEQRKLARQRSRAWLKE 1050 E EEEEEE E E +G+G+ E + E E EEE E G+E+ + E Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884 Query: 1051 GGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGA 1110 G G+E + + G G G +++ K +G EE +G EEE Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG-----EEGEGEGEEEEGEG 939 Query: 1111 KGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSG 1157 +GED E E+ + E EEEE E + + G G Sbjct: 940 EGEDGEGEGEEEE------------GEWEGEEEEGEGEGEEEGEGEG 974 Score = 44.7 bits (104), Expect = 6e-04 Identities = 47/177 (26%), Positives = 81/177 (45%), Gaps = 23/177 (12%) Query: 988 SQAAVEEEEEEEEEEEPAQGKGD-----SIEEILADSED--EEDNEEEERSRGKEQRKLA 1040 S A ++EE E+ E +G+G+ E+ LA+ E+ + D EE+E +++R+ Sbjct: 663 SSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQE----QKEREQG 718 Query: 1041 RQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSA-----DGRLII 1095 Q+ R E GG+E + + R + G G+++ G +V +G Sbjct: 719 HQKERNQEMEEGGEEEHGEGEEEEGDRE-EEEEKEGEGKEEGEGEEVEGEREKEEGERKK 777 Query: 1096 REEADGNKMEEEEGAKGEDEEM------ADPMEDVIIRNKKHQKLKHQKEAEEEELE 1146 E A + EEEG +GE EE + E + + ++ K ++E EEEE E Sbjct: 778 EERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGE 834 Score = 44.3 bits (103), Expect = 7e-04 Identities = 37/162 (22%), Positives = 72/162 (44%), Gaps = 8/162 (4%) Query: 993 EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGG 1052 E+++ E E P +G+ + E+ D E+ E++ER +G ++ + + G Sbjct: 678 EKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737 Query: 1053 GDEPLNFLDPKVAQRVLATQPGPGR----GRKKDHGFKVSAD--GRLIIREEA--DGNKM 1104 G+E + + + + G G R+K+ G + + G+ EE G Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE 797 Query: 1105 EEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELE 1146 EEE +GE++E +E + K ++ + ++E E EE E Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839 Score = 36.6 bits (83), Expect = 0.15 Identities = 57/227 (25%), Positives = 92/227 (40%), Gaps = 61/227 (26%) Query: 993 EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG--KEQRKLARQ--RSRAWL 1048 EE E EE+E KG+ IEE ++ E NEE + G KE+ ++ +A + Sbjct: 582 EEVEIPEEKEGAEDSKGNGIEE-----QEVEANEENVKVHGGRKEKTEILSDDLTDKAEV 636 Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGP-GRG----------------RKKDHGFKVSADG 1091 EG A+ V + GP GRG +++ G K G Sbjct: 637 SEG------------KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRG 684 Query: 1092 RLIIREEADGNKMEEEEGAK--GEDEEMADPMEDVIIRNKKHQKLKHQK----------E 1139 + E + E+EE K GE++E + R + HQK ++Q+ E Sbjct: 685 EMERPGEGEKELAEKEEWKKRDGEEQEQKE-------REQGHQKERNQEMEEGGEEEHGE 737 Query: 1140 AEEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGR 1186 EEEE + + + G G ++ E + +K +G+ KK+ R Sbjct: 738 GEEEEGDREEEEEKEGEGKEEGEGEE----VEGEREKEEGERKKEER 780 >gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] Length = 238 Score = 48.5 bits (114), Expect = 4e-05 Identities = 44/205 (21%), Positives = 96/205 (46%), Gaps = 9/205 (4%) Query: 966 EYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDN 1025 E R+ +K + R + E+EE+ E+EE + + ++E ++E+ Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 Query: 1026 EEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGF 1085 E+ + EQ++L Q+ + W + DE L + ++ ++ + Q R +KK Sbjct: 63 MWEQEEKMWEQQRLPEQKEKMWEQ----DERLREKEERMREQKMWQQVEKMREKKKTQEE 118 Query: 1086 KVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEEL 1145 K+ + +E + E+EE + ++E+M + E + + +K ++ + + + +EE++ Sbjct: 119 KMQEQEEKM--QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176 Query: 1146 E--IPPQYQAG-GSGIHRPVAKKAM 1167 P +AG GS P A++ M Sbjct: 177 RDVEPAGGEAGEGSPQDNPTAQEIM 201 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 48.1 bits (113), Expect = 5e-05 Identities = 55/248 (22%), Positives = 103/248 (41%), Gaps = 13/248 (5%) Query: 993 EEEEEEEEEEEPAQGK-GDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG 1051 ++E+EEEEEE+P +G G++ E++ + + E EE K + + + + +E Sbjct: 187 DKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQ 246 Query: 1052 GGD-----EPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEE 1106 G D E + D + A+ A R R K K AD R I E E Sbjct: 247 GSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQER 306 Query: 1107 EEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKA 1166 E E E M + E+ ++ + + +K A EE I + + R K+ Sbjct: 307 ERREAEERERMRE--EEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE--ERQRIKEE 362 Query: 1167 MPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARRGSQVG 1226 A + ++A+ + ++K + + K + ++ K++G+ V+ G V Sbjct: 363 EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE---KVEQKIEGKWVN 419 Query: 1227 HKNRRKDR 1234 K ++D+ Sbjct: 420 EKKAQEDK 427 Score = 42.4 bits (98), Expect = 0.003 Identities = 45/181 (24%), Positives = 84/181 (46%), Gaps = 24/181 (13%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034 R+AE R +R R + A EE + +EEE+ A + I+E + +E +EE R Sbjct: 309 REAEER-ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA 367 Query: 1035 EQRKLAR--QRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092 E+R+ AR + +A ++E ++ L ++ A Q +G K + +G+ Sbjct: 368 EERQRARAEEEEKAKVEEQKRNKQLE-------EKKHAMQETKIKGEKVEQ----KIEGK 416 Query: 1093 LIIREEADGNKME--------EEEGAK--GEDEEMADPMEDVIIRNKKHQKLKHQKEAEE 1142 + ++A +K++ EE+G K + E++ + K +K+K KE +E Sbjct: 417 WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476 Query: 1143 E 1143 E Sbjct: 477 E 477 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 47.8 bits (112), Expect = 7e-05 Identities = 63/248 (25%), Positives = 102/248 (41%), Gaps = 41/248 (16%) Query: 924 VMEAIGKLSDDMRRHFRMKL------RNLFTKFIRKFGFELVKRLLPE----EYHRVLVN 973 +++A+ KL+ D R+ + ++ R LF K R+ E K + E E L Sbjct: 2076 ILKALQKLTRDERKLTQEEIKMTKMKRALFVKE-RRLSIEQSKLDIKEWDFSEKRSELTK 2134 Query: 974 IRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEE---- 1029 K AR +R A + +EE+ EEE + S E++ D E+E EEEE Sbjct: 2135 DEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHS--EVILDDEEEGGIEEEEVIPF 2192 Query: 1030 ----------RSRG-KEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRG 1078 RG K + K + Q +E +E + LD Q L+++ R Sbjct: 2193 LKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEERE 2252 Query: 1079 RKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQK 1138 +++ REE + + EEE + E EE E+ + KK +K K + Sbjct: 2253 EEEE-------------REEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEV 2299 Query: 1139 EAEEEELE 1146 + +EE E Sbjct: 2300 QEKEEVFE 2307 Score = 43.9 bits (102), Expect = 0.001 Identities = 45/187 (24%), Positives = 86/187 (45%), Gaps = 25/187 (13%) Query: 960 KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS--IEEILA 1017 K+L EE+ +V N+ ++++ ++++ + +EEE E EE+ Q + I+E Sbjct: 1514 KKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHK 1573 Query: 1018 DSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGR 1077 + E+ R +E+RKLA++ + +E L + K+AQ + Sbjct: 1574 WARIHRKRARAEKKRAQEERKLAQEEEKLAQEE----RQLAQEERKLAQAYV-------- 1621 Query: 1078 GRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQ 1137 K++ D R + +A+G ++EE E+++ E + + KK K K + Sbjct: 1622 --------KITQDDREM--AQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAK-KWE 1670 Query: 1138 KEAEEEE 1144 K A EEE Sbjct: 1671 KVAREEE 1677 Score = 41.6 bits (96), Expect = 0.005 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 13/169 (7%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034 RK R + + + V+E E EE E + D +E+ + S +EE+ EEE R + Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREE 2259 Query: 1035 EQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLI 1094 E+ R+ +E G+E ++V + + +K+ +V + Sbjct: 2260 EE---VREEEEERKEEEEGEE----------KQVEKEEEEKKKKKKEKKKEEVQEKEEVF 2306 Query: 1095 IREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEE 1143 +E ++ E E + E+EE + +E+ + R K+ K + Q + +E+ Sbjct: 2307 EEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ 2355 Score = 38.9 bits (89), Expect = 0.031 Identities = 50/214 (23%), Positives = 95/214 (44%), Gaps = 26/214 (12%) Query: 960 KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019 +R + EE+ ++ ++A A KR + + A EEE+ +EE + AQ + + + + Sbjct: 1565 QRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKIT 1624 Query: 1020 EDEED----------NEEEERSRG----KEQRKLARQR---SRAWLKEGGGDEPLNFLDP 1062 +D+ + EE RG +E KLA++R ++ W K +E L Sbjct: 1625 QDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGG 1684 Query: 1063 KVAQ--RVLA--TQPGPGRGRKKDHGFKVSADGRLIIREEAD-----GNKMEEEEGAKGE 1113 K+A+ +LA + P R + D K A + + + ++ +EEG E Sbjct: 1685 KLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVE 1744 Query: 1114 DEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEI 1147 +++ E+ + ++ + K A+EEEL I Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEEELLI 1778 Score = 35.8 bits (81), Expect = 0.26 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 11/83 (13%) Query: 965 EEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEE------EEEEEPAQGKGDSI---EEI 1015 EE R +R+ E K + VE+EEEE E+++E Q K + EEI Sbjct: 2253 EEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEI 2312 Query: 1016 LADSEDE--EDNEEEERSRGKEQ 1036 +++ E E D EEEE S E+ Sbjct: 2313 MSEEETESLSDEEEEEESCSLEE 2335 Score = 35.8 bits (81), Expect = 0.26 Identities = 22/72 (30%), Positives = 37/72 (51%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034 +K + K+ + V EE+EE EE + D EE + S +EE + E+E + + Sbjct: 2288 KKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKE 2347 Query: 1035 EQRKLARQRSRA 1046 +Q KL QR ++ Sbjct: 2348 KQFKLQEQRRKS 2359 Score = 32.0 bits (71), Expect = 3.7 Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 9/179 (5%) Query: 993 EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGG 1052 ++EE++ ++ P QG+ ++++ + + + +EER +E ++A + +EG Sbjct: 1389 KKEEKKTFQKSPKQGR-KAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGK 1447 Query: 1053 G---DEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEA---DGNKMEE 1106 + ++ D K A + G RK +K + RL+ EE G K+ Sbjct: 1448 LVMIERTPSWQDWKKAWD--EWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSP 1505 Query: 1107 EEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKK 1165 EE ED+++ + N K K Q+ +EEE+ + + G + V ++ Sbjct: 1506 EEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEE 1564 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 47.8 bits (112), Expect = 7e-05 Identities = 59/253 (23%), Positives = 113/253 (44%), Gaps = 46/253 (18%) Query: 989 QAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWL 1048 +AA E+EEE E EEE K ++ + ++EE +EEE G+E+ + + +++ Sbjct: 490 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEE--EGQEEEEEEDEGAKSDQ 547 Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE 1108 E GG E + + G +++ + A+G EEA+ +EE+ Sbjct: 548 AEEGGSEKEGSSEKE-------------EGEQEEGETEAEAEG-----EEAEA---KEEK 586 Query: 1109 GAKGEDEEMADPME---DVIIRNKKHQKLKHQKEAEEEELEIP----PQYQAGGSGIHR- 1160 + + EE+A E D + + K K EE+ + P P + G S + + Sbjct: 587 KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 646 Query: 1161 PVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAAR 1220 PV +K K+ K V++KG+ P+++S + + K + K V+ A+ Sbjct: 647 PVEEKG------KSPVPKSPVEEKGKS------PVSKSPVEEKAKSPVP---KSPVEEAK 691 Query: 1221 RGSQVGHKNRRKD 1233 ++VG ++++ Sbjct: 692 SKAEVGKGEQKEE 704 Score = 42.7 bits (99), Expect = 0.002 Identities = 70/284 (24%), Positives = 115/284 (40%), Gaps = 57/284 (20%) Query: 993 EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG-------------KEQRKL 1039 EEE +EEEEEE K D EE ++ E + EE E+ G KE++K+ Sbjct: 529 EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 588 Query: 1040 ARQRSRAWLKEG-GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREE 1098 + KE D + P+ A+ + P +G+ V G+ + + Sbjct: 589 EEKSEEVATKEELVADAKVE--KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 646 Query: 1099 ADGNKME--------EEEG----AKGEDEEMA------DPMEDVIIRNKKHQKLKHQKEA 1140 K + EE+G +K EE A P+E+ ++K QKE Sbjct: 647 PVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEA--KSKAEVGKGEQKEE 704 Query: 1141 EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRS-K 1199 EE+E++ P+ + + K+ P + KKA+ VK++ + + + +S K Sbjct: 705 EEKEVKEAPKEE-------KVEKKEEKPKDVPEKKKAESPVKEEAVAE---VVTITKSVK 754 Query: 1200 LNRRKKMKLQG----QFKGLVKAA------RRGSQVGHKNRRKD 1233 ++ K+ K +G Q K KA GS G K RK+ Sbjct: 755 VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKE 798 Score = 39.7 bits (91), Expect = 0.018 Identities = 51/215 (23%), Positives = 90/215 (41%), Gaps = 23/215 (10%) Query: 978 EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037 E AK+ + A +EEE E+EEE Q + + +E + EE E+E S KE+ Sbjct: 505 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG 564 Query: 1038 KLARQRSRAWLKEGGGDEPLNFLDPKVAQR--VLATQPGPGRGRKKDHGFKVSADGRLII 1095 + + A E G+E + KV ++ +AT+ ++ AD ++ Sbjct: 565 EQEEGETEA---EAEGEEAEAKEEKKVEEKSEEVATKE------------ELVADAKVEK 609 Query: 1096 REEADGNKMEEEEGAKGEDEEMADPMED----VIIRNKKHQKLKH--QKEAEEEELEIPP 1149 E+A + KG+ P+E+ + ++ +K K K EE+ + P Sbjct: 610 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 669 Query: 1150 QYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKK 1184 PV K + A+ KA+ KG+ K++ Sbjct: 670 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 704 Score = 33.9 bits (76), Expect = 0.99 Identities = 36/190 (18%), Positives = 82/190 (43%), Gaps = 33/190 (17%) Query: 964 PEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEE---EEPAQGKGDS------IEE 1014 P E + + K E + + + + +A EE+ E++EE + P + K +S + E Sbjct: 686 PVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAE 745 Query: 1015 ILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPG 1074 ++ ++ + + E+E + + +++ +A EGG +E + G Sbjct: 746 VVTITKSVKVHLEKETKEEGKPLQQEKEKEKAG-GEGGSEEE-------------GSDKG 791 Query: 1075 PGRGRKKDHGFKVSADGRLIIREEA--DGNKMEEEEG--------AKGEDEEMADPMEDV 1124 RK+D +G+ + +E G+ EEE+G + ++++ D E+ Sbjct: 792 AKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEK 851 Query: 1125 IIRNKKHQKL 1134 ++ K +K+ Sbjct: 852 VVVTKTVEKI 861 Score = 32.7 bits (73), Expect = 2.2 Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 28/185 (15%) Query: 974 IRKAEARAKRHRALSQAAVEEEEE--------EEEEEEPAQGKGDSIEEILADSEDEEDN 1025 + K+ K +S++ VEE+ + EE + + GKG+ EE + E +E Sbjct: 656 VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE--EEKEVKEAP 713 Query: 1026 EEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK--KDH 1083 +EE+ + +E+ K ++ +A + P+ + VA+ V T+ K K+ Sbjct: 714 KEEKVEKKEEKPKDVPEKKKA-------ESPVK--EEAVAEVVTITKSVKVHLEKETKEE 764 Query: 1084 GFKVSADGRLIIREEADGNKMEEEEG----AKGEDEEMADPMEDVIIRNKKHQKLKHQKE 1139 G + + +E+A G EEEG AKG +E +V + + Q+ K + Sbjct: 765 GKPLQQEKE---KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS 821 Query: 1140 AEEEE 1144 EEE Sbjct: 822 GREEE 826 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 47.8 bits (112), Expect = 7e-05 Identities = 59/253 (23%), Positives = 113/253 (44%), Gaps = 46/253 (18%) Query: 989 QAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWL 1048 +AA E+EEE E EEE K ++ + ++EE +EEE G+E+ + + +++ Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEE--EGQEEEEEEDEGAKSDQ 171 Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE 1108 E GG E + + G +++ + A+G EEA+ +EE+ Sbjct: 172 AEEGGSEKEGSSEKE-------------EGEQEEGETEAEAEG-----EEAEA---KEEK 210 Query: 1109 GAKGEDEEMADPME---DVIIRNKKHQKLKHQKEAEEEELEIP----PQYQAGGSGIHR- 1160 + + EE+A E D + + K K EE+ + P P + G S + + Sbjct: 211 KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 270 Query: 1161 PVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAAR 1220 PV +K K+ K V++KG+ P+++S + + K + K V+ A+ Sbjct: 271 PVEEKG------KSPVPKSPVEEKGKS------PVSKSPVEEKAKSPVP---KSPVEEAK 315 Query: 1221 RGSQVGHKNRRKD 1233 ++VG ++++ Sbjct: 316 SKAEVGKGEQKEE 328 Score = 42.7 bits (99), Expect = 0.002 Identities = 70/284 (24%), Positives = 115/284 (40%), Gaps = 57/284 (20%) Query: 993 EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG-------------KEQRKL 1039 EEE +EEEEEE K D EE ++ E + EE E+ G KE++K+ Sbjct: 153 EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 212 Query: 1040 ARQRSRAWLKEG-GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREE 1098 + KE D + P+ A+ + P +G+ V G+ + + Sbjct: 213 EEKSEEVATKEELVADAKVE--KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 270 Query: 1099 ADGNKME--------EEEG----AKGEDEEMA------DPMEDVIIRNKKHQKLKHQKEA 1140 K + EE+G +K EE A P+E+ ++K QKE Sbjct: 271 PVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEA--KSKAEVGKGEQKEE 328 Query: 1141 EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRS-K 1199 EE+E++ P+ + + K+ P + KKA+ VK++ + + + +S K Sbjct: 329 EEKEVKEAPKEE-------KVEKKEEKPKDVPEKKKAESPVKEEAVAE---VVTITKSVK 378 Query: 1200 LNRRKKMKLQG----QFKGLVKAA------RRGSQVGHKNRRKD 1233 ++ K+ K +G Q K KA GS G K RK+ Sbjct: 379 VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKE 422 Score = 39.7 bits (91), Expect = 0.018 Identities = 51/215 (23%), Positives = 90/215 (41%), Gaps = 23/215 (10%) Query: 978 EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037 E AK+ + A +EEE E+EEE Q + + +E + EE E+E S KE+ Sbjct: 129 EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG 188 Query: 1038 KLARQRSRAWLKEGGGDEPLNFLDPKVAQR--VLATQPGPGRGRKKDHGFKVSADGRLII 1095 + + A E G+E + KV ++ +AT+ ++ AD ++ Sbjct: 189 EQEEGETEA---EAEGEEAEAKEEKKVEEKSEEVATKE------------ELVADAKVEK 233 Query: 1096 REEADGNKMEEEEGAKGEDEEMADPMED----VIIRNKKHQKLKH--QKEAEEEELEIPP 1149 E+A + KG+ P+E+ + ++ +K K K EE+ + P Sbjct: 234 PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 293 Query: 1150 QYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKK 1184 PV K + A+ KA+ KG+ K++ Sbjct: 294 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 328 Score = 33.9 bits (76), Expect = 0.99 Identities = 36/190 (18%), Positives = 82/190 (43%), Gaps = 33/190 (17%) Query: 964 PEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEE---EEPAQGKGDS------IEE 1014 P E + + K E + + + + +A EE+ E++EE + P + K +S + E Sbjct: 310 PVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAE 369 Query: 1015 ILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPG 1074 ++ ++ + + E+E + + +++ +A EGG +E + G Sbjct: 370 VVTITKSVKVHLEKETKEEGKPLQQEKEKEKAG-GEGGSEEE-------------GSDKG 415 Query: 1075 PGRGRKKDHGFKVSADGRLIIREEA--DGNKMEEEEG--------AKGEDEEMADPMEDV 1124 RK+D +G+ + +E G+ EEE+G + ++++ D E+ Sbjct: 416 AKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEK 475 Query: 1125 IIRNKKHQKL 1134 ++ K +K+ Sbjct: 476 VVVTKTVEKI 485 Score = 32.7 bits (73), Expect = 2.2 Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 28/185 (15%) Query: 974 IRKAEARAKRHRALSQAAVEEEEE--------EEEEEEPAQGKGDSIEEILADSEDEEDN 1025 + K+ K +S++ VEE+ + EE + + GKG+ EE + E +E Sbjct: 280 VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE--EEKEVKEAP 337 Query: 1026 EEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK--KDH 1083 +EE+ + +E+ K ++ +A + P+ + VA+ V T+ K K+ Sbjct: 338 KEEKVEKKEEKPKDVPEKKKA-------ESPVK--EEAVAEVVTITKSVKVHLEKETKEE 388 Query: 1084 GFKVSADGRLIIREEADGNKMEEEEG----AKGEDEEMADPMEDVIIRNKKHQKLKHQKE 1139 G + + +E+A G EEEG AKG +E +V + + Q+ K + Sbjct: 389 GKPLQQEKE---KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS 445 Query: 1140 AEEEE 1144 EEE Sbjct: 446 GREEE 450 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 47.4 bits (111), Expect = 9e-05 Identities = 25/64 (39%), Positives = 37/64 (57%) Query: 977 AEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQ 1036 +E +K+ LS +EEEEEEEEEE + + EE + E+EE+ EEEE +E+ Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304 Query: 1037 RKLA 1040 + A Sbjct: 305 EEAA 308 Score = 44.7 bits (104), Expect = 6e-04 Identities = 22/64 (34%), Positives = 36/64 (56%) Query: 977 AEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQ 1036 A + + + + E+EEEEEEEEE + + + EE + E+EE+ EEEE +E+ Sbjct: 244 ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303 Query: 1037 RKLA 1040 + A Sbjct: 304 EEEA 307 Score = 40.8 bits (94), Expect = 0.008 Identities = 20/61 (32%), Positives = 33/61 (54%) Query: 978 EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037 E A + + + EEE+EEEEE + + + EE + E+EE+ EEEE +E+ Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300 Query: 1038 K 1038 + Sbjct: 301 E 301 Score = 35.8 bits (81), Expect = 0.26 Identities = 36/167 (21%), Positives = 67/167 (40%), Gaps = 30/167 (17%) Query: 987 LSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRA 1046 L+ + EE EE+ A G I +L ++ + +EE E+ Sbjct: 169 LNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGL-------------- 214 Query: 1047 WLKEGGGDEPLNFLDPKVAQRVLATQPGPGRG----RKKDHGFKVSADGRLIIREEADGN 1102 F+ P+ A+ V+ + +D + S+ + I+ E + Sbjct: 215 ------------FIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262 Query: 1103 KMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPP 1149 + EEEE + EDEE + E+ ++ ++ + ++E EEEE E P Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309 Score = 33.9 bits (76), Expect = 0.99 Identities = 18/45 (40%), Positives = 23/45 (51%) Query: 993 EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037 EEEEEEEEEEE + + + EE D +ED + E R Sbjct: 285 EEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELR 329 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 47.4 bits (111), Expect = 9e-05 Identities = 49/272 (18%), Positives = 122/272 (44%), Gaps = 33/272 (12%) Query: 978 EARAKRHRALSQAAVEE----------EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEE 1027 E + +RH ++ A++E EEEEE + E + + +E E++ EE Sbjct: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940 Query: 1028 EERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFK- 1086 E+ R + +++ ++R R + K D+ L + +++L +P R ++++ ++ Sbjct: 941 EQLLREEREKRRRQERERQYRK----DKKLQ----QKEEQLLGEEPEKRRRQEREKKYRE 992 Query: 1087 ---VSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEE 1143 + + ++REE + + +E E + +E+ E ++ ++ ++L+ ++ E Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052 Query: 1144 ELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRR 1203 E E+ Q + G R ++ +Y+ ++ +++ L R + +R Sbjct: 1053 EEEL-QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ----------LLREEPEKR 1101 Query: 1204 KKMKLQGQFKGLVKAARRGSQVGHKNRRKDRR 1235 ++ + + Q + + + Q+ + R K RR Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRR 1133 Score = 47.4 bits (111), Expect = 9e-05 Identities = 59/266 (22%), Positives = 116/266 (43%), Gaps = 41/266 (15%) Query: 976 KAEARAKRHRALSQAAVEEEEE--EEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG 1033 + E KR R + EEE+ +E EE+P + + E E+E ++E+ R Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ----ERDRKFREEELRHQEQGRKFL 1377 Query: 1034 KEQRKLARQ-RSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092 +E+++L RQ R R +LKE ++ L Q + R+ D K + + Sbjct: 1378 EEEQRLRRQERERKFLKE---------------EQQLRCQEREQQLRQ-DRDRKFREEEQ 1421 Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQ 1152 + R+E D EEE+ + ++ E E+ +R ++H+K + +++ +E E Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE------ 1475 Query: 1153 AGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGR----PDPYAYIPLNRSKLNRRKKMKL 1208 +HR + E + ++ + D K + + +P +L+R+++ + Sbjct: 1476 ---QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532 Query: 1209 QGQFKGLVKAARRGSQVGHKNRRKDR 1234 Q + ++ RG Q RR+DR Sbjct: 1533 FLQEEQQLRRQERGQQ-----RRQDR 1553 Score = 43.5 bits (101), Expect = 0.001 Identities = 43/187 (22%), Positives = 85/187 (45%), Gaps = 15/187 (8%) Query: 960 KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019 ++LL EE + R+ + R K++R + EEE+ EE E + + E Sbjct: 971 EQLLGEEPEK-----RRRQEREKKYREEEELQQEEEQLLREEREKRRRQE---WERQYRK 1022 Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGR 1079 +DE EEE+ R + +++ ++R R + +E E L + ++ T+ R Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREE----EELQQEEEQLLGEERETRRRQELER 1078 Query: 1080 KKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVI---IRNKKHQKLKH 1136 + ++ + ++REE + + +E E E+EE+ E ++ ++ Q+L+ Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138 Query: 1137 QKEAEEE 1143 Q EEE Sbjct: 1139 QYREEEE 1145 Score = 42.0 bits (97), Expect = 0.004 Identities = 39/182 (21%), Positives = 80/182 (43%), Gaps = 30/182 (16%) Query: 960 KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019 +R LPEE K + R +R + EEEE+ + E AQ Sbjct: 808 QRFLPEEEE-------KEQRRRQRREREKELQFLEEEEQLQRRERAQ-----------QL 849 Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGR 1079 ++EED +E++ R + Q + Q+ R L+E + K + L +P Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEE----------ERKRRRHTLYAKPALQEQL 899 Query: 1080 KKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKE 1139 +K+ + + + REE + + +E+E E+E++ E+ ++R ++ ++ + ++E Sbjct: 900 RKEQQL-LQEEEEELQREEREKRRRQEQERQYREEEQLQQE-EEQLLREEREKRRRQERE 957 Query: 1140 AE 1141 + Sbjct: 958 RQ 959 Score = 42.0 bits (97), Expect = 0.004 Identities = 44/190 (23%), Positives = 86/190 (45%), Gaps = 13/190 (6%) Query: 960 KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019 ++LL EE + R+ R ++ R + ++EEE+ E + K E Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE-KRRRQERERQYR 961 Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKV---AQRVLATQPGPG 1076 +D++ ++EE+ G+E K RQ +E +E L + ++ + Q Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYRE---EEELQQEEEQLLREEREKRRRQEWER 1018 Query: 1077 RGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVI---IRNKKHQK 1133 + RKKD ++ + ++REE + +++E E E+EE+ E ++ ++ Q+ Sbjct: 1019 QYRKKD---ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075 Query: 1134 LKHQKEAEEE 1143 L+ Q EEE Sbjct: 1076 LERQYRKEEE 1085 Score = 41.2 bits (95), Expect = 0.006 Identities = 36/172 (20%), Positives = 80/172 (46%), Gaps = 13/172 (7%) Query: 978 EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037 + R ++ R Q +E+E + E+ Q + ++ L D + E+E+ + +E++ Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634 Query: 1038 KLARQ-RSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK--KDHGFKVSADGRLI 1094 +L RQ R R +L+E +P++ ++ Q R RK ++ + + + Sbjct: 1635 QLHRQERDRKFLEE----------EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684 Query: 1095 IREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELE 1146 R+E D EEE+ + ++ E E+ +R ++ ++ ++E +E E Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736 Score = 40.8 bits (94), Expect = 0.008 Identities = 41/188 (21%), Positives = 90/188 (47%), Gaps = 10/188 (5%) Query: 963 LPEEYHRVLVNIRKAEARAKRHRALSQ-AAVEEEEEEEEEEEPAQGKGDSIEEILADSED 1021 L +E ++L R+ R +R R + ++++EE+ EEP + + E+ E+ Sbjct: 936 LQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK--KYREE 993 Query: 1022 EEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKK 1081 EE +EEE+ +E+ K RQ W ++ + L + ++ + + R R+ Sbjct: 994 EELQQEEEQLLREEREKRRRQE---WERQYRKKDELQQEEEQLLREEREKRRLQERERQY 1050 Query: 1082 DHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKE-- 1139 ++ + ++ EE + + +E E ++EE+ E+ ++R + ++ + ++E Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE-EEQLLREEPEKRRRQERERQ 1109 Query: 1140 -AEEEELE 1146 EEEEL+ Sbjct: 1110 CREEEELQ 1117 Score = 40.8 bits (94), Expect = 0.008 Identities = 51/274 (18%), Positives = 110/274 (40%), Gaps = 29/274 (10%) Query: 963 LPEEYHRVLVNIRKAEARAKRHRAL-SQAAVEEEEEEEEEEEPAQGKGDSIEEILADSED 1021 L +E ++L R+ R + R + V++EEE+ EEP + + +E E+ Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER--QYREE 1173 Query: 1022 EEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKK 1081 EE +EEE+ +EQ K ++R R + +E L Q R R + Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREE----------------EELQRQKRKQRYRDE 1217 Query: 1082 DHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE 1141 D +D + E + + + KG + E +ED +R+++ Q+ E Sbjct: 1218 DQ----RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273 Query: 1142 EEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLN 1201 ++E + + + + P E ++ + + K++ R L + Sbjct: 1274 QQERDREQERRRWQQ------RDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327 Query: 1202 RRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRR 1235 +R++ + +F+ + + + + + +DR+ Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361 Score = 39.7 bits (91), Expect = 0.018 Identities = 62/265 (23%), Positives = 114/265 (43%), Gaps = 32/265 (12%) Query: 916 HLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIR 975 H KH Q E K + RR + +K + ++ + +KR EE + + Sbjct: 434 HEQKHEQERREQRLKREQEERRDW-LKREEETERHEQERRKQQLKRDQEEERRERWLKLE 492 Query: 976 KAEARAKRHRALSQAAVEEEEEEE------EEEEPAQGKGDSIEEILADSEDEEDNEEEE 1029 + E R ++ R Q E+EE E EEEE Q + S +++ E++ E+ Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL----RREQEERREQ 548 Query: 1030 RSRGKEQRKLARQRSRAWLK---EGGGDEPLNFLDPKVAQRVLATQPGPGRGR-KKDHGF 1085 + +E+++L ++R LK E D+ L + + QR+ Q R K++ Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608 Query: 1086 KVSADGR---LIIREEADGN------KMEEEEGAKGED--EEMADPMEDVIIRNKKHQKL 1134 ++ + R + REE + K EE+E + + E + E + R ++ ++L Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL 668 Query: 1135 ------KHQKEAEEEELEIPPQYQA 1153 +H++E E+EL Q QA Sbjct: 669 EQRLKREHEEERREQELAEEEQEQA 693 Score = 38.1 bits (87), Expect = 0.052 Identities = 37/186 (19%), Positives = 81/186 (43%), Gaps = 14/186 (7%) Query: 963 LPEEYHRVLVNIRKAEARAKRHRAL-SQAAVEEEEEEEEEEEPAQGKGDSIEEILADSED 1021 L +E ++L R+ R + R + +++EEE+ EEP + + E + E+ Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE-EE 1114 Query: 1022 EEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKK 1081 E EEE+ R + +++ ++ R + +E + +++L +P R ++ Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQE--------EEQLLREEPEKRRRQEL 1166 Query: 1082 DHGFK----VSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQ 1137 + ++ + + ++REE + + E E + E+E + + LK Q Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQ 1226 Query: 1138 KEAEEE 1143 E E+E Sbjct: 1227 WEPEKE 1232 Score = 37.7 bits (86), Expect = 0.068 Identities = 44/189 (23%), Positives = 83/189 (43%), Gaps = 16/189 (8%) Query: 971 LVNIRKAEARAKRHRALSQAAVEE------EEEEEEEEEPAQGKGDSIEEILADSEDEED 1024 L+ R+ E +R + EE ++ +E+E E A+G+ S ++ + D + Sbjct: 109 LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168 Query: 1025 NEEE-ERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLD-PKVAQRVLATQPGPGRGRKKD 1082 +EE R R + Q + R+ L+ G E F D ++ +R L GR K+ Sbjct: 169 RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ 228 Query: 1083 HGFKVSADGRLIIREEADGNKME-----EEEGAKGEDEEMADPM--EDVIIRNKKHQKLK 1135 + D EE + K E EEE + E+ + + E+ +R + Q+L+ Sbjct: 229 QR-RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR 287 Query: 1136 HQKEAEEEE 1144 +++ EE++ Sbjct: 288 RERQEEEQQ 296 Score = 37.0 bits (84), Expect = 0.12 Identities = 38/178 (21%), Positives = 76/178 (42%), Gaps = 21/178 (11%) Query: 976 KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILAD-SEDEEDNEEEERSRGK 1034 + E + +R + L + EE E++ E+E + + +E D + EE+ E E+ R K Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473 Query: 1035 EQ--RKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092 +Q R +R WLK L + + Q Q + +++ K + Sbjct: 474 QQLKRDQEEERRERWLK-------LEEEERREQQERREQQLRREQEERREQRLKRQEE-- 524 Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPM-----EDVIIRNKKHQKLKHQKEAEEEEL 1145 EE ++ E+ + E EE + + E + + ++ Q+LK ++E ++L Sbjct: 525 ----EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578 Score = 35.8 bits (81), Expect = 0.26 Identities = 43/199 (21%), Positives = 87/199 (43%), Gaps = 13/199 (6%) Query: 957 ELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEIL 1016 E +++L +E R + + R +R + L + EE E++EE Q + + EE Sbjct: 276 EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335 Query: 1017 ADS---EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQP 1073 E EE E++ R +E+R+ Q+ R +E ++ L ++ L + Sbjct: 336 EQQLRREQEERREQQLRREQEEERR--EQQLRREQEEERREQQLRREQQLRREQQLRREQ 393 Query: 1074 GPGRGRKKDHGFKVSADGRL----IIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNK 1129 R ++ ++ + +L +R E + +EEE + E + + E + R + Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE--RHEQKHEQERREQRLKREQ 451 Query: 1130 KHQK--LKHQKEAEEEELE 1146 + ++ LK ++E E E E Sbjct: 452 EERRDWLKREEETERHEQE 470 Score = 35.4 bits (80), Expect = 0.34 Identities = 39/179 (21%), Positives = 74/179 (41%), Gaps = 24/179 (13%) Query: 969 RVLVNIRKA---EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDN 1025 R L+ +R+ E + +R + EEEE+E + E K + + E Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272 Query: 1026 EEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGF 1085 EEEE+ R E+++L R+R + + QR+ Q RK++ Sbjct: 273 EEEEQLRKLERQELRRERQE---------------EEQQQQRLRREQQ---LRRKQEEER 314 Query: 1086 KVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144 + + R RE+ + + +EE + E + E + R ++ ++ + Q E+EE Sbjct: 315 REQQEER---REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370 Score = 35.4 bits (80), Expect = 0.34 Identities = 37/192 (19%), Positives = 87/192 (45%), Gaps = 11/192 (5%) Query: 974 IRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGD------SIEEILADSEDEE-DNE 1026 +++ E + + + +EEE + +E Q + D E++L + E+++ + Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ 1687 Query: 1027 EEERSRGKEQRKLARQ-RSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGF 1085 E +R +E+++L RQ R R +L+E + L + + R+++ Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR 1747 Query: 1086 KVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKE---AEE 1142 K+ + +L E + +E + E+E++ E+ +R+++ + ++E E Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807 Query: 1143 EELEIPPQYQAG 1154 EE ++ PQ + G Sbjct: 1808 EEQQLRPQQRDG 1819 Score = 35.0 bits (79), Expect = 0.44 Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 12/97 (12%) Query: 965 EEYHRVLVNIRKAEARAKRHRALSQAAVEEEEE------------EEEEEEPAQGKGDSI 1012 +E+ + +RK E + + Q ++EEEE E +EEE Q + Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303 Query: 1013 EEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLK 1049 +++ E+E ++EER +E+R+ +R L+ Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340 Score = 34.7 bits (78), Expect = 0.58 Identities = 45/226 (19%), Positives = 89/226 (39%), Gaps = 23/226 (10%) Query: 925 MEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRH 984 +E +L + R FR + + L + ++ + R EE ++ R + R + Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508 Query: 985 RALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRS 1044 R+ EEE++ + Q K E+ L E + ++ + +E+ +L ++R Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568 Query: 1045 RAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKM 1104 L D + KV R+++ K D + + R+E Sbjct: 1569 EQQLSRQERDRKFRLEEQKV--------------RRQEQERKFMEDEQQLRRQEGQQQLR 1614 Query: 1105 EEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQ 1150 +E + EDE++ E+ Q+L H++E + + LE PQ Sbjct: 1615 QERDRKFREDEQLLQEREE--------QQL-HRQERDRKFLEEEPQ 1651 Score = 34.7 bits (78), Expect = 0.58 Identities = 38/175 (21%), Positives = 77/175 (44%), Gaps = 16/175 (9%) Query: 978 EARAKRHRALSQAA-VEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQ 1036 E + HR Q ++EE++ +E Q + D + + + ++ EE++ SR + Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578 Query: 1037 RK--LARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLI 1094 RK L Q+ R +E E L + Q+ L + R ++D + + + Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE--RDRKFREDEQLLQEREEQQL 1636 Query: 1095 IREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQ----KEAEEEEL 1145 R+E D +EEE + ++ E +R+ + +K + + +E EE++L Sbjct: 1637 HRQERDRKFLEEEPQLRRQEREQQ-------LRHDRDRKFREEEQLLQEGEEQQL 1684 Score = 34.3 bits (77), Expect = 0.76 Identities = 45/211 (21%), Positives = 87/211 (41%), Gaps = 23/211 (10%) Query: 978 EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037 E + R + L + EEE+ +E E+ + + +IL + + + EE++ R + R Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771 Query: 1038 K------LARQRSRAWLKEGGGDEPL---NFLDPKVAQRVLATQPGPGRGRKKDHGFKVS 1088 K L ++R L+ D L + ++ L Q G+ R ++ ++ Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831 Query: 1089 ADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIP 1148 + +R+E D EE+ A E E+ + ++ QK + ++E + E I Sbjct: 1832 EQEQR-LRQERDRQYRAEEQFATQEKSR----REEQELWQEEEQKRRQERERKLREEHIR 1886 Query: 1149 PQYQAGGSGIHRPVAKKAMPGAEYKAKKAKG 1179 Q + HR V E K+++ KG Sbjct: 1887 RQQKE--EQRHRQV-------GEIKSQEGKG 1908 Score = 33.5 bits (75), Expect = 1.3 Identities = 46/215 (21%), Positives = 94/215 (43%), Gaps = 13/215 (6%) Query: 940 RMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEE 999 R++ R + +R+ E ++LL E + L R+ E R KR + + + + EEE Sbjct: 527 RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR-EQRLKREQEERRDQLLKREEER 585 Query: 1000 EEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNF 1059 ++ + + + +E+ L E E +EE R + ++ + +R + LK +E Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE---- 641 Query: 1060 LDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMAD 1119 + Q++ Q R K + + RL E + E+E A+ E E+ + Sbjct: 642 ---RRQQQLRREQQERREQRLKREEEEERLEQRLKREHE---EERREQELAEEEQEQARE 695 Query: 1120 PMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAG 1154 ++ I K +L+ + +A + ++ P+ Q G Sbjct: 696 RIKSRI--PKWQWQLESEADARQSKVYSRPRKQEG 728 Score = 32.7 bits (73), Expect = 2.2 Identities = 56/278 (20%), Positives = 108/278 (38%), Gaps = 51/278 (18%) Query: 976 KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG-- 1033 ++EA A++ + S+ +E + +E+E + + +S + + +EEE+ R Sbjct: 709 ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFT 768 Query: 1034 -------KEQR---------KLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGR 1077 K +R L QR R E FL + + Q R Sbjct: 769 WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ---RR 825 Query: 1078 GRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQ 1137 R+K+ F + + +L RE A +++EEE ED+E E ++ QK + Q Sbjct: 826 EREKELQF-LEEEEQLQRRERA--QQLQEEEDGLQEDQERRRSQE-----QRRDQKWRWQ 877 Query: 1138 KEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNR 1197 E E + H AK A+ K ++ + +++ L R Sbjct: 878 LEEERKRRR------------HTLYAKPALQEQLRKEQQLLQEEEEE----------LQR 915 Query: 1198 SKLNRRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRR 1235 + +R++ + + Q++ + + Q+ + R K RR Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953 >gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens] Length = 2211 Score = 46.6 bits (109), Expect = 1e-04 Identities = 38/108 (35%), Positives = 49/108 (45%), Gaps = 17/108 (15%) Query: 974 IRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG 1033 ++K +AK R + +EE+E EEEE + + S EE E EE+ EEEE G Sbjct: 927 LKKERLKAKLQRKKKKRKGSDEEDEGEEEESSSSEESSSEE----EEMEEEEEEEEFGPG 982 Query: 1034 K----EQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGR 1077 EQ K R WL G D L V + V A +PGP R Sbjct: 983 MQEVIEQHKFEAHR---WLARGKEDNEL------VVELVPAGKPGPER 1021 Score = 32.3 bits (72), Expect = 2.9 Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 15/112 (13%) Query: 1077 RGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADP-MEDVIIRNK--KHQK 1133 R +KK G +G ++ + EEEE + E+EE P M++VI ++K H+ Sbjct: 938 RKKKKRKGSDEEDEGEEEESSSSEESSSEEEEMEEEEEEEEFGPGMQEVIEQHKFEAHRW 997 Query: 1134 LKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKG 1185 L KE E +E+ P AG G R Y+ + G+V K G Sbjct: 998 LARGKEDNELVVELVP---AGKPGPERNT---------YEVQVVTGNVPKAG 1037 >gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa [Homo sapiens] Length = 517 Score = 46.6 bits (109), Expect = 1e-04 Identities = 64/282 (22%), Positives = 120/282 (42%), Gaps = 31/282 (10%) Query: 964 PEEYHRVLVNIRKAEARAKRHRALSQAAV-------EEEEEEEEEEEPAQGKGDSIEEIL 1016 P HR L E +R++ L+ ++ +++++E+EEE+ +G+ + E + Sbjct: 148 PLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRI 207 Query: 1017 ADSEDE-EDNEEEERSRGKEQRKLARQRSRAWLKEGG-------GDEPLNFLDPK----V 1064 D ED+ E + + + G+E ++ + + +A L +GG G + F D Sbjct: 208 HDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFE 267 Query: 1065 AQRVLATQPGPGRGRKKDHGFKVSA----DGRLIIREEADGNKMEEEEGAKGEDEEMADP 1120 Q V G +++ K A +G + E++D ++ EEE ED+E + Sbjct: 268 GQEVDYMSDGSSSSQEEPES-KAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEE 326 Query: 1121 MEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGD 1180 + + KK +K ++ EE +I + S + +AKK P + + K + G Sbjct: 327 KKAPTPQEKKRRKDSSEESDSSEESDIDSE---ASSALF--MAKKKTP-PKRERKPSGGS 380 Query: 1181 VKKKGRP-DPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARR 1221 + RP P A S L QG+ + AA+R Sbjct: 381 SRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKR 422 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 46.2 bits (108), Expect = 2e-04 Identities = 52/195 (26%), Positives = 81/195 (41%), Gaps = 20/195 (10%) Query: 975 RKAEARAKRHRALSQAAVEE----EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEER 1030 RK E R+ R R A + E EEEE++E P++ + L E+EE+ EEEE Sbjct: 222 RKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEE 281 Query: 1031 SRGKEQRKLARQRSR-----AWLKEGGGD----EPLNFLD--PKV-AQRVLATQPGPGRG 1078 +E+ Q+SR KE G + +P +D PK +Q + G Sbjct: 282 DDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFT 341 Query: 1079 RKKDHGFKVSADGRLIIREEADGNKMEEEE----GAKGEDEEMADPMEDVIIRNKKHQKL 1134 R ++ K + +E + +EEEE ++G E+ P + ++K L Sbjct: 342 RSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASL 401 Query: 1135 KHQKEAEEEELEIPP 1149 E E E PP Sbjct: 402 VALPEQTASEEETPP 416 Score = 39.3 bits (90), Expect = 0.023 Identities = 46/160 (28%), Positives = 61/160 (38%), Gaps = 35/160 (21%) Query: 989 QAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWL 1048 Q+++E E E P K SI E DS+DE+ + E RS RQ A L Sbjct: 188 QSSLERPELELSRHSPR--KSSSISEEKGDSDDEKPRKGERRS------SRVRQARAAKL 239 Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE 1108 EG P + Q P R +R AD N EEE Sbjct: 240 SEGS--------QPAEEEE---DQETPSRN----------------LRVRADRNLKTEEE 272 Query: 1109 GAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIP 1148 + E+EE D E+ +K ++ KE +EE EIP Sbjct: 273 EEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIP 312 Score = 36.2 bits (82), Expect = 0.20 Identities = 44/207 (21%), Positives = 87/207 (42%), Gaps = 25/207 (12%) Query: 957 ELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS----- 1011 E V LLP ++ ++ + E RH +++ EE+ + ++E+P +G+ S Sbjct: 177 EGVASLLPPDFQS---SLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQ 233 Query: 1012 -----IEEILADSEDEEDNEEEERS-RGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVA 1065 + E +E+EED E R+ R + R L + +E D+ D + Sbjct: 234 ARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQ 293 Query: 1066 QRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE-----GAKGEDEEMADP 1120 + ++ P K+ G ++ + +E + +E+E G +E A Sbjct: 294 K----SREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEA-- 347 Query: 1121 MEDVIIRNKKHQKLKHQKEAEEEELEI 1147 + + R ++ +++K EEEE EI Sbjct: 348 RKSHLARQQQEKEMKTTSPLEEEEREI 374 Score = 34.7 bits (78), Expect = 0.58 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%) Query: 974 IRKAEARAKRHRALSQAAVEEEEEE--EEEEEPAQGKGDSIEEIL----ADSEDEEDNEE 1027 ++K RA+R + + E+EEEE E E+E + + +E + D E E Sbjct: 1235 VQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERE 1294 Query: 1028 EERSRGKEQRKLARQRSR 1045 ER RG R R R R Sbjct: 1295 RERDRGDRDRDRERDRER 1312 Score = 31.6 bits (70), Expect = 4.9 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 10/83 (12%) Query: 975 RKAEARAKRHRALSQAAVEE---EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031 R+ EA +R+R L + E E + E E E + +GD D + E D E Sbjct: 1263 REKEAERERNRQLEREKRREHSRERDRERERERERDRGD------RDRDRERDRERGRER 1316 Query: 1032 RGKEQRKLARQRSRAW-LKEGGG 1053 ++ ++ +R RSR+ +++ GG Sbjct: 1317 DRRDTKRHSRSRSRSTPVRDRGG 1339 Score = 30.8 bits (68), Expect = 8.4 Identities = 29/155 (18%), Positives = 67/155 (43%), Gaps = 24/155 (15%) Query: 976 KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEI----------LADSE-DEED 1024 ++ R ++ RA S+ E++E+ +EE PA+ D + L DS+ +++ Sbjct: 1179 RSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKE 1238 Query: 1025 NEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHG 1084 E ER++ +E+R+ ++ +E + N + +R + + R R+++ Sbjct: 1239 AERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERE-- 1296 Query: 1085 FKVSADGRLIIREEADGNKMEEEEGAKGEDEEMAD 1119 R+ D ++ E + +G + + D Sbjct: 1297 -----------RDRGDRDRDRERDRERGRERDRRD 1320 >gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] Length = 185 Score = 46.2 bits (108), Expect = 2e-04 Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 1/66 (1%) Query: 978 EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK-EQ 1036 E A++ + + VEEEEEE EEEE + K + EE + E EED EEEE+ K E+ Sbjct: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168 Query: 1037 RKLARQ 1042 K+ + Sbjct: 169 EKVEEE 174 Score = 42.4 bits (98), Expect = 0.003 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 1/70 (1%) Query: 975 RKAEARAKRHRALSQAAVEEEE-EEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG 1033 R A A+ A VEEEE EEEEEE + K + EE + E EE+ EE+E Sbjct: 101 RTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEE 160 Query: 1034 KEQRKLARQR 1043 KE +K+ ++ Sbjct: 161 KEGKKMEEEK 170 Score = 39.7 bits (91), Expect = 0.018 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 972 VNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031 +++ + A + Q EEEE EEEEE +EE + E EED EEEE+ Sbjct: 97 LSVARTAALVAEECSAQQGLPVEEEEVEEEEE-------EVEEEEKEEEKEEDEEEEEKE 149 Query: 1032 RGKEQRKLARQRSRAWLKEGGGDEPLN 1058 KE+ + ++ ++E +E ++ Sbjct: 150 EEKEEDEEEEEKEGKKMEEEKVEEEID 176 Score = 31.2 bits (69), Expect = 6.4 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 4/62 (6%) Query: 965 EEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEED 1024 EE + + E ++ + EEE+EE+EEEE +GK E++ E+E D Sbjct: 121 EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV----EEEID 176 Query: 1025 NE 1026 E Sbjct: 177 TE 178 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 45.8 bits (107), Expect = 3e-04 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 25/189 (13%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEE--DNEEEERSR 1032 R+AE RAKR EEEE + +EE Q EEIL ++EE EEEE +R Sbjct: 736 REAEMRAKR---------EEEERKRQEELRRQQ-----EEILRRQQEEERKRREEEELAR 781 Query: 1033 GKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092 K++ L RQR + +E + +R+ R+++ + + Sbjct: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEEL 833 Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE-EEELEIPPQY 1151 L +EE EEE A+ EE ME+ R + ++ + +KE E + + E+ Q Sbjct: 834 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 893 Query: 1152 QAGGSGIHR 1160 Q + R Sbjct: 894 QQQQEALRR 902 Score = 30.8 bits (68), Expect = 8.4 Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 18/172 (10%) Query: 994 EEEEEEEEEEPAQGKGDSIE-EILADSEDEEDNEEEERSRGKEQ---RKLARQRSRAWLK 1049 E+ ++ E+ + A+ + + E E+ A E+EE +EE R +E+ R+ +R R + Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777 Query: 1050 EGGGDEPLNFLDPKVAQRV-LATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKME--- 1105 E + L + Q + L Q ++++ + + R REE + K E Sbjct: 778 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---REEEERRKQEELL 834 Query: 1106 ---EEEGAK--GEDEEMADPMEDVIIR-NKKHQKLKH-QKEAEEEELEIPPQ 1150 EEE AK E+EE +E+ +R ++ +L+H ++E + +ELE+ Q Sbjct: 835 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 886 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 45.8 bits (107), Expect = 3e-04 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 25/189 (13%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEE--DNEEEERSR 1032 R+AE RAKR EEEE + +EE Q EEIL ++EE EEEE +R Sbjct: 763 REAEMRAKR---------EEEERKRQEELRRQQ-----EEILRRQQEEERKRREEEELAR 808 Query: 1033 GKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092 K++ L RQR + +E + +R+ R+++ + + Sbjct: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEEL 860 Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE-EEELEIPPQY 1151 L +EE EEE A+ EE ME+ R + ++ + +KE E + + E+ Q Sbjct: 861 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 920 Query: 1152 QAGGSGIHR 1160 Q + R Sbjct: 921 QQQQEALRR 929 Score = 30.8 bits (68), Expect = 8.4 Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 18/172 (10%) Query: 994 EEEEEEEEEEPAQGKGDSIE-EILADSEDEEDNEEEERSRGKEQ---RKLARQRSRAWLK 1049 E+ ++ E+ + A+ + + E E+ A E+EE +EE R +E+ R+ +R R + Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804 Query: 1050 EGGGDEPLNFLDPKVAQRV-LATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKME--- 1105 E + L + Q + L Q ++++ + + R REE + K E Sbjct: 805 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---REEEERRKQEELL 861 Query: 1106 ---EEEGAK--GEDEEMADPMEDVIIR-NKKHQKLKH-QKEAEEEELEIPPQ 1150 EEE AK E+EE +E+ +R ++ +L+H ++E + +ELE+ Q Sbjct: 862 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 45.8 bits (107), Expect = 3e-04 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 25/189 (13%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEE--DNEEEERSR 1032 R+AE RAKR EEEE + +EE Q EEIL ++EE EEEE +R Sbjct: 742 REAEMRAKR---------EEEERKRQEELRRQQ-----EEILRRQQEEERKRREEEELAR 787 Query: 1033 GKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092 K++ L RQR + +E + +R+ R+++ + + Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEEL 839 Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE-EEELEIPPQY 1151 L +EE EEE A+ EE ME+ R + ++ + +KE E + + E+ Q Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899 Query: 1152 QAGGSGIHR 1160 Q + R Sbjct: 900 QQQQEALRR 908 Score = 30.8 bits (68), Expect = 8.4 Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 18/172 (10%) Query: 994 EEEEEEEEEEPAQGKGDSIE-EILADSEDEEDNEEEERSRGKEQ---RKLARQRSRAWLK 1049 E+ ++ E+ + A+ + + E E+ A E+EE +EE R +E+ R+ +R R + Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783 Query: 1050 EGGGDEPLNFLDPKVAQRV-LATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKME--- 1105 E + L + Q + L Q ++++ + + R REE + K E Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---REEEERRKQEELL 840 Query: 1106 ---EEEGAK--GEDEEMADPMEDVIIR-NKKHQKLKH-QKEAEEEELEIPPQ 1150 EEE AK E+EE +E+ +R ++ +L+H ++E + +ELE+ Q Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892 >gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 45.8 bits (107), Expect = 3e-04 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 25/189 (13%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEE--DNEEEERSR 1032 R+AE RAKR EEEE + +EE Q EEIL ++EE EEEE +R Sbjct: 742 REAEMRAKR---------EEEERKRQEELRRQQ-----EEILRRQQEEERKRREEEELAR 787 Query: 1033 GKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092 K++ L RQR + +E + +R+ R+++ + + Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEEL 839 Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE-EEELEIPPQY 1151 L +EE EEE A+ EE ME+ R + ++ + +KE E + + E+ Q Sbjct: 840 LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899 Query: 1152 QAGGSGIHR 1160 Q + R Sbjct: 900 QQQQEALRR 908 Score = 30.8 bits (68), Expect = 8.4 Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 18/172 (10%) Query: 994 EEEEEEEEEEPAQGKGDSIE-EILADSEDEEDNEEEERSRGKEQ---RKLARQRSRAWLK 1049 E+ ++ E+ + A+ + + E E+ A E+EE +EE R +E+ R+ +R R + Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783 Query: 1050 EGGGDEPLNFLDPKVAQRV-LATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKME--- 1105 E + L + Q + L Q ++++ + + R REE + K E Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---REEEERRKQEELL 840 Query: 1106 ---EEEGAK--GEDEEMADPMEDVIIR-NKKHQKLKH-QKEAEEEELEIPPQ 1150 EEE AK E+EE +E+ +R ++ +L+H ++E + +ELE+ Q Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892 >gi|21361639 DIPB protein [Homo sapiens] Length = 344 Score = 45.4 bits (106), Expect = 3e-04 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 11/116 (9%) Query: 976 KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035 +AE + ++ R + A EE E EEE E + + + E +D E EED+EEE + Sbjct: 80 EAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQES 139 Query: 1036 QRKLARQRSRAWLKEGGGDEPLNFLDPKV---AQRVLATQPGPGRGRKKDHGFKVS 1088 + + Q EG + F DP++ A+RV + + DHG +S Sbjct: 140 EAEEDNQEEGESEAEGETEAESEF-DPEIEMEAERV-------AKRKCPDHGLDLS 187 Score = 35.0 bits (79), Expect = 0.44 Identities = 18/55 (32%), Positives = 29/55 (52%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEE 1029 R+ E+ A + + EEE E EEE + +S E+ + EDE+++E EE Sbjct: 89 REIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEE 143 Score = 34.3 bits (77), Expect = 0.76 Identities = 34/146 (23%), Positives = 57/146 (39%), Gaps = 9/146 (6%) Query: 1005 AQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKV 1064 A G G + EE+ D +E +E + G E+ + R+ + + FL + Sbjct: 2 ASGVGAAFEELPHDGTCDECEPDE--APGAEE--VCRECGFCYCRRHAEAHRQKFLSHHL 57 Query: 1065 AQRVLATQ----PGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADP 1120 A+ V +Q P G G K+ +V + I EA EEE E+ E + Sbjct: 58 AEYVHGSQAWTPPADGEGAGKEEA-EVKVEQEREIESEAGEESESEEESESEEESETEEE 116 Query: 1121 MEDVIIRNKKHQKLKHQKEAEEEELE 1146 ED + + ++ +E E E Sbjct: 117 SEDESDEESEEDSEEEMEDEQESEAE 142 >gi|13540523 nucleosomal binding protein 1 [Homo sapiens] Length = 282 Score = 45.1 bits (105), Expect = 4e-04 Identities = 39/165 (23%), Positives = 77/165 (46%), Gaps = 9/165 (5%) Query: 982 KRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEE--RSRGKEQRKL 1039 K+ ++ EEE+++E+EE+ + KG++ +E D + EED +E++ +G++ ++ Sbjct: 115 KKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED-KDEKGEEDGKEDKNGNEKGEDAKEK 173 Query: 1040 ARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEA 1099 + K G D D K + T G K+ G K + +E Sbjct: 174 EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK 233 Query: 1100 DGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144 + +E+EG G +EE ED+ K+ ++ K + E +E++ Sbjct: 234 EREDGKEDEG--GNEEEAGKEKEDL----KEEEEGKEEDEIKEDD 272 Score = 42.4 bits (98), Expect = 0.003 Identities = 49/205 (23%), Positives = 91/205 (44%), Gaps = 31/205 (15%) Query: 962 LLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSED 1021 ++ E+Y+ N + EA+ A + VE +EE E+ + G+ E + A+ ++ Sbjct: 71 VVEEDYNE---NAKNGEAKITEAPASEKEIVEVKEENIEDA--TEKGGEKKEAVAAEVKN 125 Query: 1022 EEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLN----FLDPKVAQRVLATQPGPGR 1077 EE++++E+ E++ A + + E G E N D K + + G G Sbjct: 126 EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGN 185 Query: 1078 G---------RKKDHGFKVSADGRLIIREEADG-NKMEEEEG----AKGEDEEMADPMED 1123 G K++ K + DG +E DG K +++EG K +++E D ED Sbjct: 186 GEDGKEKGEDEKEEEDRKETGDG----KENEDGKEKGDKKEGKDVKVKEDEKEREDGKED 241 Query: 1124 ----VIIRNKKHQKLKHQKEAEEEE 1144 K+ + LK ++E +EE+ Sbjct: 242 EGGNEEEAGKEKEDLKEEEEGKEED 266 >gi|42476169 Paf1, RNA polymerase II associated factor, homolog [Homo sapiens] Length = 531 Score = 44.7 bits (104), Expect = 6e-04 Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 19/162 (11%) Query: 972 VNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031 +N ++ EA+ R L EEEEEEE E E + G E+ S ++E +E+E Sbjct: 356 MNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH-- 413 Query: 1032 RGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADG 1091 G E + R A K G G++ + + + A R K+ F AD Sbjct: 414 SGSESEREEGDRDEASDKSGSGEDESSEDEARAA-------------RDKEEIFGSDADS 460 Query: 1092 RLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQK 1133 ++AD + + + G D + R++ H + Sbjct: 461 ----EDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSR 498 Score = 36.6 bits (83), Expect = 0.15 Identities = 36/185 (19%), Positives = 78/185 (42%), Gaps = 12/185 (6%) Query: 937 RHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAK---RHRALSQAAVE 993 R + ++N +K + F + + Y+ + +R ++ RAK + + V+ Sbjct: 293 REYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVK 352 Query: 994 EEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGG 1053 + E+E E + + +E + E+EE+ E EE+ G + +++ + KEG Sbjct: 353 HRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEE--QEKGSSSEKEGSE 410 Query: 1054 DEPLNFLDPKVA--QRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK 1111 DE + + + + G G + + + D +EE G+ + E+ A Sbjct: 411 DEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARD-----KEEIFGSDADSEDDAD 465 Query: 1112 GEDEE 1116 +DE+ Sbjct: 466 SDDED 470 Score = 31.6 bits (70), Expect = 4.9 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 13/82 (15%) Query: 983 RHRALSQAAVEEEEEEEEEEEPAQGK-----GDSIEEILADSEDEE--------DNEEEE 1029 R A ++ E+E E+E A+ K D+ E ADS+DE+ DN+ + Sbjct: 425 RDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDS 484 Query: 1030 RSRGKEQRKLARQRSRAWLKEG 1051 S G QR + RS + G Sbjct: 485 GSNGGGQRSRSHSRSASPFPSG 506 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 44.3 bits (103), Expect = 7e-04 Identities = 49/195 (25%), Positives = 89/195 (45%), Gaps = 41/195 (21%) Query: 936 RRHFRMKLRNLFTKFIRKF-GFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAA--V 992 RR KLR + + +E+ +R EY + +AE +R R +++ A + Sbjct: 443 RRKLERKLREKEAAYQERLKNWEIRERKKTREYEK------EAEREEERRREMAKEAKRL 496 Query: 993 EE--EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKE 1050 +E E+ +++ ++P +G ++++ L D E E + +E +R R KE+ + RQR L E Sbjct: 497 KEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQR---LLAE 553 Query: 1051 G--GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE 1108 G D L ++ + +R QP I++E + + EEE+ Sbjct: 554 GHPDPDAELQRMEQEAERR---RQPQ--------------------IKQEPESEEEEEEK 590 Query: 1109 GAKGEDEEMADPMED 1123 K E E +PME+ Sbjct: 591 QEKEEKRE--EPMEE 603 Score = 38.5 bits (88), Expect = 0.040 Identities = 44/194 (22%), Positives = 77/194 (39%), Gaps = 13/194 (6%) Query: 965 EEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEED 1024 EE R L++ ++ R + + +E+E +E E+E + + + E + E Sbjct: 270 EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329 Query: 1025 NEEEERSRGKE-QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDH 1083 E ER + KE +R+ R R R KE D + +R R R+K Sbjct: 330 EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389 Query: 1084 GFKVSADGRLIIRE-----------EADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQ 1132 + + R RE E + + E E K + + + ED R K + Sbjct: 390 DRERERE-REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448 Query: 1133 KLKHQKEAEEEELE 1146 KL+ ++ A +E L+ Sbjct: 449 KLREKEAAYQERLK 462 Score = 38.5 bits (88), Expect = 0.040 Identities = 64/298 (21%), Positives = 123/298 (41%), Gaps = 32/298 (10%) Query: 942 KLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEA-RAKRHRALSQAAVEEEEEEEE 1000 K R+ K + G + +R E+ R R+ E R +R R + E+E+E E Sbjct: 283 KFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERE 342 Query: 1001 EEEPAQGKGDSIEEILADSEDEEDNEEE---------ERSRGKEQ---RKLARQRSRAWL 1048 E D +E D + E D + + +RSR +E+ R+ R+R R Sbjct: 343 RERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERE 402 Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHG---FKVSADGRLIIREEADGNKM- 1104 +E + + +R + R R++D + + +L +E A ++ Sbjct: 403 REREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLK 462 Query: 1105 --EEEEGAKGEDEEMADPMEDVIIRN--KKHQKLKHQKEAEEEELEIPPQYQAGGSGIHR 1160 E E K + E E+ R K+ ++LK E +++ + P Y+ GS + + Sbjct: 463 NWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR--GSALQK 520 Query: 1161 PV--AKKAMPGAEYKAKKAKGDVKK-------KGRPDPYAYIPLNRSKLNRRKKMKLQ 1209 + +K M E K+ K ++++ +G PDP A + + RR++ +++ Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIK 578 Score = 37.4 bits (85), Expect = 0.089 Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 34/204 (16%) Query: 976 KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035 K+ R + + E E E E E E + + E D E++EE+ R K Sbjct: 387 KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKL 446 Query: 1036 QRKL-----------------ARQRSRAWLKEGGGDEPLNFLDPKVAQRVL--------- 1069 +RKL R+++R + KE +E K A+R+ Sbjct: 447 ERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDD 506 Query: 1070 ATQPGPGRG-----RKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMAD--PME 1122 P RG R +D ++ AD R RE+ + ++ + A+G + A+ ME Sbjct: 507 RDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRME 566 Query: 1123 DVIIRNKKHQKLKHQKEAEEEELE 1146 R ++ Q +K + E+EEEE E Sbjct: 567 QEAERRRQPQ-IKQEPESEEEEEE 589 Score = 32.0 bits (71), Expect = 3.7 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%) Query: 957 ELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEIL 1016 E+ +RLL E + +++ E A+R R E EEEEEE+ Q K + EE + Sbjct: 545 EIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEK---QEKEEKREEPM 601 Query: 1017 ADSEDEE 1023 + E+ E Sbjct: 602 EEEEEPE 608 Score = 30.8 bits (68), Expect = 8.4 Identities = 36/173 (20%), Positives = 63/173 (36%), Gaps = 19/173 (10%) Query: 991 AVEEEEEE------------------EEEEEPAQGKGDSIEEILADSEDEEDNEEEERSR 1032 A+E EE++ EEE+ + + IE+ + E E + E E R R Sbjct: 266 AIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRER 325 Query: 1033 GKE-QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADG 1091 +E +R+ R++ + +E D + + R R R D S Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385 Query: 1092 RLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144 E + + E E + + E E R ++ +K K + E+EE Sbjct: 386 EKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 44.3 bits (103), Expect = 7e-04 Identities = 52/262 (19%), Positives = 102/262 (38%), Gaps = 34/262 (12%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034 R++ +R+ ++ + E E E+E + + + E+ S + E RSR + Sbjct: 274 RRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSR 333 Query: 1035 EQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGF-KVSADGRL 1093 E R RSR+ ++ GD R + RGR++D + K + R Sbjct: 334 E-----RHRSRSRSRDRKGDR---------RDRDREREKENERGRRRDRDYDKERGNERE 379 Query: 1094 IIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQA 1153 RE + E+ + E+++ + +D R+ K K +K + E + ++ Sbjct: 380 KERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRS 439 Query: 1154 GGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFK 1213 R K++ ++ K+ K K + K+K N+R + QG+ Sbjct: 440 RS----RNAGKRSRSRSKEKSSKHKNESKEKS---------------NKRSRSGSQGRTD 480 Query: 1214 GLVKAARRGSQVGHKNRRKDRR 1235 + K+ +R + RK R Sbjct: 481 SVEKSKKREHSPSKEKSRKRSR 502 Score = 34.3 bits (77), Expect = 0.76 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 6/80 (7%) Query: 966 EYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDN 1025 +Y + N R+ E R R+ Q + E EE++ +E+ + D D + Sbjct: 369 DYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRD------DKRDSKKE 422 Query: 1026 EEEERSRGKEQRKLARQRSR 1045 ++ RSR +E++ +R RSR Sbjct: 423 KKHSRSRSRERKHRSRSRSR 442 Score = 32.3 bits (72), Expect = 2.9 Identities = 34/176 (19%), Positives = 65/176 (36%), Gaps = 7/176 (3%) Query: 975 RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034 R E R R+ + + + E E+E +G+ + + E E R R K Sbjct: 331 RSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSK 390 Query: 1035 EQRKLARQRSRAWLKEGGGDEPL--NFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092 EQR + KE D + D K ++ ++ + R + R Sbjct: 391 EQRSRGEVEEKKH-KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR 449 Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQ----KLKHQKEAEEEE 1144 +E++ +K E +E + + D + ++KK + K K +K + +E Sbjct: 450 SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKE 505 >gi|5453567 craniofacial development protein 1 [Homo sapiens] Length = 299 Score = 44.3 bits (103), Expect = 7e-04 Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 45/227 (19%) Query: 975 RKAE---ARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031 RKA+ AR +R LS EEEEEE+ ++ +G S SE+E+D E+E+ Sbjct: 53 RKAQSIPARKRRQGGLSL------EEEEEEDANSESEGSS-------SEEEDDAAEQEKG 99 Query: 1032 RGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADG 1091 G E + ++ W LN + PK ++ P KK + ++ Sbjct: 100 IGSEDAR-KKKEDELWASF------LNDVGPK-------SKVPPSTQVKKGEETEETSSS 145 Query: 1092 RLIIREEADGNKMEEEEGAK--------GEDEEMADPMEDVIIRNKKHQKLKHQKEAEEE 1143 +L+++ E + K +E E K GE+ + ++V +K+ + Q E E+ Sbjct: 146 KLLVKAE-ELEKPKETEKVKITKVFDFAGEEVRVT---KEVDATSKEAKSFFKQNEKEKP 201 Query: 1144 ELEIPPQYQA--GGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPD 1188 + +P + GSG+ R ++ G + AKK K +K + D Sbjct: 202 QANVPSALPSLPAGSGLKRSSGMSSLLG-KIGAKKQKMSTLEKSKLD 247 >gi|28274705 family with sequence similarity 9, member A [Homo sapiens] Length = 332 Score = 44.3 bits (103), Expect = 7e-04 Identities = 40/132 (30%), Positives = 57/132 (43%), Gaps = 24/132 (18%) Query: 937 RHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAV---- 992 RH R KL N+ ++I ++ +E AEA A A + A V Sbjct: 169 RHTR-KLLNVLKEYI-------AEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVE 220 Query: 993 ---------EEEEEEEEEEEPAQGKGDSIEEILA---DSEDEEDNEEEERSRGKEQRKLA 1040 EEE+EEEEEE +G G+ EE E EE+ EEEE +EQ K Sbjct: 221 DEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAF 280 Query: 1041 RQRSRAWLKEGG 1052 +++ + W + G Sbjct: 281 QEKQKRWQQPTG 292 Score = 33.1 bits (74), Expect = 1.7 Identities = 46/236 (19%), Positives = 95/236 (40%), Gaps = 57/236 (24%) Query: 909 VTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYH 968 + M + H+A ++ + A ++ + +R K +N + ++K + KR + Sbjct: 115 IHTMKLEHIAADIKKGLAAKREMIKIDKAAYR-KTKNTIERALKKKQLKRQKR--DYRHT 171 Query: 969 RVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIE---------EILADS 1019 R L+N+ K A +++++E EE E A ++ E++ Sbjct: 172 RKLLNVLK-----------EYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVE 220 Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGR 1079 ++EE+ +EEE + +E+ + +EGGG+E + G G G Sbjct: 221 DEEEEEKEEEEEKEEEEEE--------GEEEGGGEE---------------GEEGGGGG- 256 Query: 1080 KKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLK 1135 +G EE + + EEEE K E+ + +R+ + +++K Sbjct: 257 ----------EGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMK 302 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 43.9 bits (102), Expect = 0.001 Identities = 39/189 (20%), Positives = 88/189 (46%), Gaps = 15/189 (7%) Query: 960 KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019 ++ + EE + K + + ++ R + E+EE+ +E+EE K EE + + Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE----KMWEQEEKMWEQ 621 Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGR 1079 E+E+ +E+E +++ K+ Q + W +E E + + K+ ++ Q + R Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE----EKMREQEEKMREQEEKMQGQEEKMR 677 Query: 1080 KKDHGFKVSADGRLIIREEADGNKME---EEEGAKGEDEEMADPMEDVIIRNKKHQKLKH 1136 +++ + + E+ G + + +EE G++E+M E +K ++++ Sbjct: 678 EQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE----MREKEERIRD 733 Query: 1137 QKEAEEEEL 1145 QKE +E L Sbjct: 734 QKEKMQERL 742 Score = 43.5 bits (101), Expect = 0.001 Identities = 43/177 (24%), Positives = 85/177 (48%), Gaps = 15/177 (8%) Query: 978 EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037 E K R + +E+E E+E+E + K +E ++E+ E+EE+ R +E+ Sbjct: 273 EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE- 331 Query: 1038 KLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIRE 1097 K+ RQ R W +E + + + K+ + R R+K+ ++ ++ +E Sbjct: 332 KMWRQEERLWEQE----KQMREQEQKMRDQEERMWEQDERLREKEE--RMREQEKMWEQE 385 Query: 1098 EADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQK----LKHQKEAEEEELEIPPQ 1150 E KM+EEE + +++M + E + + +K QK + Q+E E ++ +P Q Sbjct: 386 E----KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 438 Score = 38.9 bits (89), Expect = 0.031 Identities = 35/178 (19%), Positives = 84/178 (47%), Gaps = 18/178 (10%) Query: 974 IRKAEARAKRHRAL--SQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031 +R+ E R + + + ++EEE E E+ + + +++ E + +E+N E+ Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 427 Query: 1032 RGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADG 1091 + +Q++L Q+ + W +E ++ + + +++ + G+ +K K Sbjct: 428 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE--EKIRDQEEMWGQEKKMWRQEK----- 480 Query: 1092 RLIIREEADGNKMEEEEGAKGEDEEMADPME-----DVIIRNKKHQKLKHQKEAEEEE 1144 +RE+ D E+EE + ++++M D E D +R K+ + + +K ++EE Sbjct: 481 ---MREQED-QMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534 Score = 37.0 bits (84), Expect = 0.12 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 14/165 (8%) Query: 980 RAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKL 1039 R K R Q + ++EE+ EE+ Q + E+ D E++ EE R R K+ R+ Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQ----EKKTWDQEEKMREEERMREREKKMREE 572 Query: 1040 ARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEA 1099 K +E + + K+ ++ Q + +++ + E+ Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK----------MWEQE 622 Query: 1100 DGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144 + +KM+E+E E EE E+ + ++ + + +K E+EE Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667 Score = 34.7 bits (78), Expect = 0.58 Identities = 46/206 (22%), Positives = 88/206 (42%), Gaps = 28/206 (13%) Query: 956 FELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEI 1015 +E +++ EE R + E R + EE E+EE+E Q + +E Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441 Query: 1016 LADSEDEEDNEE-----EERSRGKE-----------QRKLARQRSRAWLKEGGGDEPLNF 1059 L + E ++ EE EE+ R +E Q K+ Q + W +E E + Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE----EKMRD 497 Query: 1060 LDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMAD 1119 + K+ + R R+K+ ++ ++ +EE KM EE+ + ++++ D Sbjct: 498 QEQKMWDQEERMWEQDERLREKEE--RMREQKKMWQQEE----KMREEKKTQEQEKKTWD 551 Query: 1120 PMEDVIIRNKKHQKLKHQKEAEEEEL 1145 E +R ++ + + +K EEEE+ Sbjct: 552 QEEK--MREEERMREREKKMREEEEM 575 Score = 34.3 bits (77), Expect = 0.76 Identities = 45/201 (22%), Positives = 91/201 (45%), Gaps = 30/201 (14%) Query: 974 IRKAEARAKRHRALSQAAVEEEEEEE---EEEEPAQGKGDSI---EEILADSE------- 1020 +R+ E + + L + + +E+EE E+EE + + + + EE L + E Sbjct: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351 Query: 1021 ----DEEDN--EEEERSRGKEQRKLARQRSRAWLKEGG--GDEPLNFLDPKVAQRVLATQ 1072 D+E+ E++ER R KE+R R++ + W +E +E + + K+ + + Sbjct: 352 QKMRDQEERMWEQDERLREKEERM--REQEKMWEQEEKMQEEERIREREKKMREEEETMR 409 Query: 1073 PGPGRGRKKDHGF-----KVSADGRLIIREEA--DGNKMEEEEGAKGEDEEMADPMEDVI 1125 + +K++ K RL ++E + KM+E+E E EE E++ Sbjct: 410 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469 Query: 1126 IRNKKHQKLKHQKEAEEEELE 1146 + KK + + +E E++ E Sbjct: 470 GQEKKMWRQEKMREQEDQMWE 490 Score = 33.1 bits (74), Expect = 1.7 Identities = 44/177 (24%), Positives = 82/177 (46%), Gaps = 29/177 (16%) Query: 993 EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGG 1052 +EE+ ++EE Q K +E + + ED+ E+EE+ R +EQ K+ Q R W + Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW-EQEEKMRDQEQ-KMWDQEERMWEQ--- 512 Query: 1053 GDEPLNFLDPKVA-QRVLATQPGPGRGRKK---------DHGFKVSADGRLIIRE----- 1097 DE L + ++ Q+ + Q R KK D K+ + R+ RE Sbjct: 513 -DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571 Query: 1098 ------EADGNKMEEEEGAKGEDEEMADPMEDVIIRNKK--HQKLKHQKEAEEEELE 1146 E + E+EE + ++E+M + E + + +K Q+ K ++ EE++++ Sbjct: 572 EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628 Score = 32.3 bits (72), Expect = 2.9 Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 12/170 (7%) Query: 980 RAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKL 1039 R ++ R E+EE+ ++E+ + + + E +DE E+EER R EQ+K+ Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE-----QDERLREKEERMR--EQKKM 529 Query: 1040 ARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEA 1099 +Q + ++ ++ D + R + +++ + ++ +EE Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589 Query: 1100 ---DGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEA--EEEE 1144 KM E+E E EE E+ + ++ K++ Q+E E+EE Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639 >gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 43.9 bits (102), Expect = 0.001 Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 33/190 (17%) Query: 989 QAAVEEEEEEEEE-----EEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQR 1043 QA EE EE EEE E PA DS ++++ E EEEE+ R E+++ + + Sbjct: 1230 QAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEE 1289 Query: 1044 SRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNK 1103 + +EP +P+ + A + DH DG L E+ K Sbjct: 1290 QQEL------EEP----EPEEEEDAAAE-----TAQNDDHDADDEDDGHL----ESTKKK 1330 Query: 1104 MEEEEGAKGEDEEMADPMEDVIIRN--KKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRP 1161 EE+ + + +E E + N K +K+K ++E E + E P + Sbjct: 1331 ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTS------- 1383 Query: 1162 VAKKAMPGAE 1171 V + M G+E Sbjct: 1384 VVSEQMAGSE 1393 Score = 39.7 bits (91), Expect = 0.018 Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 26/176 (14%) Query: 976 KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035 + E ++ R + EEE++E EE + + D+ E + + + D+E++ + Sbjct: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328 Query: 1036 QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLII 1095 +++L Q +R +KE G + +FLD + +K K + L Sbjct: 1329 KKELEEQPTREDVKEEPGVQE-SFLDANM--------------QKSREKIKDKEETELDS 1373 Query: 1096 REEADGNK----MEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEI 1147 EE + E+ G++ + EE + E++I +LK ++E EL++ Sbjct: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI-------ELKEEEEIPHSELDL 1422 Score = 37.4 bits (85), Expect = 0.089 Identities = 40/199 (20%), Positives = 85/199 (42%), Gaps = 27/199 (13%) Query: 952 RKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS 1011 RK GF+L + ++P ++ + +A R + ++ EE E +E+ P + Sbjct: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES---EETVEPKEDMPLPEERKE 1225 Query: 1012 IEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLAT 1071 EE+ A++E+ E+ EEE+ + + + A + +P+V + Sbjct: 1226 EEEMQAEAEEAEEGEEEDAA--------SSEVPAASPADSSNSPETETKEPEVEEEEEKP 1277 Query: 1072 QPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGE----DEEMADPMEDVIIR 1127 + + + ++ ++E + + EEEE A E D+ AD +D + Sbjct: 1278 RVSEEQRQSEEE------------QQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE 1325 Query: 1128 NKKHQKLKHQKEAEEEELE 1146 + K ++L+ Q E+ + E Sbjct: 1326 STKKKELEEQPTREDVKEE 1344 Score = 32.7 bits (73), Expect = 2.2 Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 9/125 (7%) Query: 922 QLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKR--LLPEEYHRVLVNIRKAEA 979 Q+ ++ + KL+ + L +L R F +++R L+ + ++ +N+R + Sbjct: 710 QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDV 769 Query: 980 RAKRHR----ALSQAAVEEEEEEEEEE---EPAQGKGDSIEEILADSEDEEDNEEEERSR 1032 + R +S + V EEEEEE EE E Q + +E + S E+ E++ S Sbjct: 770 DPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSV 829 Query: 1033 GKEQR 1037 E++ Sbjct: 830 ESEKK 834 Score = 32.7 bits (73), Expect = 2.2 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%) Query: 992 VEEEEEEEEEEE--PAQ-----GKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRS 1044 ++EEEEEE+E E P + D + + +D EE+E S + + + S Sbjct: 1067 IDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVS 1126 Query: 1045 RAWLKEGGGDEPLNFLDPKVAQRVLATQPGP-GRGRKKDH---------GFKVSAD---- 1090 + D + L+P + + + P G+ RK H GFK+S + Sbjct: 1127 LLRKR----DVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPV 1182 Query: 1091 -GRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144 + + E + E EE +P ED+ + ++ ++ + Q EAEE E Sbjct: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE 1237 >gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 43.9 bits (102), Expect = 0.001 Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 33/190 (17%) Query: 989 QAAVEEEEEEEEE-----EEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQR 1043 QA EE EE EEE E PA DS ++++ E EEEE+ R E+++ + + Sbjct: 1230 QAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEE 1289 Query: 1044 SRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNK 1103 + +EP +P+ + A + DH DG L E+ K Sbjct: 1290 QQEL------EEP----EPEEEEDAAAE-----TAQNDDHDADDEDDGHL----ESTKKK 1330 Query: 1104 MEEEEGAKGEDEEMADPMEDVIIRN--KKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRP 1161 EE+ + + +E E + N K +K+K ++E E + E P + Sbjct: 1331 ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTS------- 1383 Query: 1162 VAKKAMPGAE 1171 V + M G+E Sbjct: 1384 VVSEQMAGSE 1393 Score = 39.7 bits (91), Expect = 0.018 Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 26/176 (14%) Query: 976 KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035 + E ++ R + EEE++E EE + + D+ E + + + D+E++ + Sbjct: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328 Query: 1036 QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLII 1095 +++L Q +R +KE G + +FLD + +K K + L Sbjct: 1329 KKELEEQPTREDVKEEPGVQE-SFLDANM--------------QKSREKIKDKEETELDS 1373 Query: 1096 REEADGNK----MEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEI 1147 EE + E+ G++ + EE + E++I +LK ++E EL++ Sbjct: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI-------ELKEEEEIPHSELDL 1422 Score = 37.4 bits (85), Expect = 0.089 Identities = 40/199 (20%), Positives = 85/199 (42%), Gaps = 27/199 (13%) Query: 952 RKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS 1011 RK GF+L + ++P ++ + +A R + ++ EE E +E+ P + Sbjct: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES---EETVEPKEDMPLPEERKE 1225 Query: 1012 IEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLAT 1071 EE+ A++E+ E+ EEE+ + + + A + +P+V + Sbjct: 1226 EEEMQAEAEEAEEGEEEDAA--------SSEVPAASPADSSNSPETETKEPEVEEEEEKP 1277 Query: 1072 QPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGE----DEEMADPMEDVIIR 1127 + + + ++ ++E + + EEEE A E D+ AD +D + Sbjct: 1278 RVSEEQRQSEEE------------QQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE 1325 Query: 1128 NKKHQKLKHQKEAEEEELE 1146 + K ++L+ Q E+ + E Sbjct: 1326 STKKKELEEQPTREDVKEE 1344 Score = 32.7 bits (73), Expect = 2.2 Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 9/125 (7%) Query: 922 QLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKR--LLPEEYHRVLVNIRKAEA 979 Q+ ++ + KL+ + L +L R F +++R L+ + ++ +N+R + Sbjct: 710 QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDV 769 Query: 980 RAKRHR----ALSQAAVEEEEEEEEEE---EPAQGKGDSIEEILADSEDEEDNEEEERSR 1032 + R +S + V EEEEEE EE E Q + +E + S E+ E++ S Sbjct: 770 DPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSV 829 Query: 1033 GKEQR 1037 E++ Sbjct: 830 ESEKK 834 Score = 32.7 bits (73), Expect = 2.2 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%) Query: 992 VEEEEEEEEEEE--PAQ-----GKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRS 1044 ++EEEEEE+E E P + D + + +D EE+E S + + + S Sbjct: 1067 IDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVS 1126 Query: 1045 RAWLKEGGGDEPLNFLDPKVAQRVLATQPGP-GRGRKKDH---------GFKVSAD---- 1090 + D + L+P + + + P G+ RK H GFK+S + Sbjct: 1127 LLRKR----DVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPV 1182 Query: 1091 -GRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144 + + E + E EE +P ED+ + ++ ++ + Q EAEE E Sbjct: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE 1237 >gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3 [Homo sapiens] Length = 2004 Score = 43.9 bits (102), Expect = 0.001 Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 33/190 (17%) Query: 989 QAAVEEEEEEEEE-----EEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQR 1043 QA EE EE EEE E PA DS ++++ E EEEE+ R E+++ + + Sbjct: 1230 QAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEE 1289 Query: 1044 SRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNK 1103 + +EP +P+ + A + DH DG L E+ K Sbjct: 1290 QQEL------EEP----EPEEEEDAAAE-----TAQNDDHDADDEDDGHL----ESTKKK 1330 Query: 1104 MEEEEGAKGEDEEMADPMEDVIIRN--KKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRP 1161 EE+ + + +E E + N K +K+K ++E E + E P + Sbjct: 1331 ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTS------- 1383 Query: 1162 VAKKAMPGAE 1171 V + M G+E Sbjct: 1384 VVSEQMAGSE 1393 Score = 39.7 bits (91), Expect = 0.018 Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 26/176 (14%) Query: 976 KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035 + E ++ R + EEE++E EE + + D+ E + + + D+E++ + Sbjct: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328 Query: 1036 QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLII 1095 +++L Q +R +KE G + +FLD + +K K + L Sbjct: 1329 KKELEEQPTREDVKEEPGVQE-SFLDANM--------------QKSREKIKDKEETELDS 1373 Query: 1096 REEADGNK----MEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEI 1147 EE + E+ G++ + EE + E++I +LK ++E EL++ Sbjct: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI-------ELKEEEEIPHSELDL 1422 Score = 37.4 bits (85), Expect = 0.089 Identities = 40/199 (20%), Positives = 85/199 (42%), Gaps = 27/199 (13%) Query: 952 RKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS 1011 RK GF+L + ++P ++ + +A R + ++ EE E +E+ P + Sbjct: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES---EETVEPKEDMPLPEERKE 1225 Query: 1012 IEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLAT 1071 EE+ A++E+ E+ EEE+ + + + A + +P+V + Sbjct: 1226 EEEMQAEAEEAEEGEEEDAA--------SSEVPAASPADSSNSPETETKEPEVEEEEEKP 1277 Query: 1072 QPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGE----DEEMADPMEDVIIR 1127 + + + ++ ++E + + EEEE A E D+ AD +D + Sbjct: 1278 RVSEEQRQSEEE------------QQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE 1325 Query: 1128 NKKHQKLKHQKEAEEEELE 1146 + K ++L+ Q E+ + E Sbjct: 1326 STKKKELEEQPTREDVKEE 1344 Score = 32.7 bits (73), Expect = 2.2 Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 9/125 (7%) Query: 922 QLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKR--LLPEEYHRVLVNIRKAEA 979 Q+ ++ + KL+ + L +L R F +++R L+ + ++ +N+R + Sbjct: 710 QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDV 769 Query: 980 RAKRHR----ALSQAAVEEEEEEEEEE---EPAQGKGDSIEEILADSEDEEDNEEEERSR 1032 + R +S + V EEEEEE EE E Q + +E + S E+ E++ S Sbjct: 770 DPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSV 829 Query: 1033 GKEQR 1037 E++ Sbjct: 830 ESEKK 834 Score = 32.7 bits (73), Expect = 2.2 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%) Query: 992 VEEEEEEEEEEE--PAQ-----GKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRS 1044 ++EEEEEE+E E P + D + + +D EE+E S + + + S Sbjct: 1067 IDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVS 1126 Query: 1045 RAWLKEGGGDEPLNFLDPKVAQRVLATQPGP-GRGRKKDH---------GFKVSAD---- 1090 + D + L+P + + + P G+ RK H GFK+S + Sbjct: 1127 LLRKR----DVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPV 1182 Query: 1091 -GRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144 + + E + E EE +P ED+ + ++ ++ + Q EAEE E Sbjct: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE 1237 >gi|27597090 suppressor of Ty 6 homolog [Homo sapiens] Length = 1726 Score = 43.9 bits (102), Expect = 0.001 Identities = 45/184 (24%), Positives = 81/184 (44%), Gaps = 16/184 (8%) Query: 992 VEEEEEEEEEEEPA---QGKGDSIEEILADSEDEEDNEEEERSRG--KEQRKLARQRSRA 1046 VEEE+++EEEEE Q + +++ + D +DE++ EE+E S E ++R R Sbjct: 31 VEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRT 90 Query: 1047 WLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEE 1106 + D+ + ++ + +V + G R K D +EE + + E Sbjct: 91 SFDDRLEDDDFDLIEENLGVKV---KRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAE 147 Query: 1107 EEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPP-QYQAGGSGIHRPVAKK 1165 E GE EE + ME + ++E ++EE +I G + +P +K Sbjct: 148 EIFQDGEGEEGQEAMEAPMAP-------PEEEEEDDEESDIDDFIVDDDGQPLKKPKWRK 200 Query: 1166 AMPG 1169 +PG Sbjct: 201 KLPG 204 Score = 40.4 bits (93), Expect = 0.011 Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 27/179 (15%) Query: 995 EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGD 1054 E E EE EE +G+ + + +EED++EEE E+ L Q + LK D Sbjct: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEE-----EEENLDDQDEQGNLKGFIND 60 Query: 1055 EPLNFLDPKVAQRVLATQPGPGR---GRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK 1111 + D + + G G KK + S D RL E+ D + +EE G K Sbjct: 61 DD----DEDEGEEDEGSDSGDSEDDVGHKKRK--RTSFDDRL---EDDDFDLIEENLGVK 111 Query: 1112 GED-------EEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVA 1163 + ++M+D +D +++ K +H+KEA EE+ + + G + P+A Sbjct: 112 VKRGQKYRRVKKMSDDEDD---DEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMA 167 Score = 34.7 bits (78), Expect = 0.58 Identities = 19/69 (27%), Positives = 35/69 (50%) Query: 961 RLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSE 1020 RL +++ + N+ R +++R + + + +E+++EEE + K EEI D E Sbjct: 95 RLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGE 154 Query: 1021 DEEDNEEEE 1029 EE E E Sbjct: 155 GEEGQEAME 163 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 47,268,773 Number of Sequences: 37866 Number of extensions: 2196148 Number of successful extensions: 30178 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 310 Number of HSP's successfully gapped in prelim test: 385 Number of HSP's that attempted gapping in prelim test: 15969 Number of HSP's gapped (non-prelim): 6846 length of query: 1236 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1122 effective length of database: 13,930,794 effective search space: 15630350868 effective search space used: 15630350868 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.