Guide to the Human Genome
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Search of human proteins with 223278381

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223278381 ribosomal RNA processing 12 homolog isoform 2
[Homo sapiens]
         (1236 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo...  2437   0.0  
gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo...  2141   0.0  
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    57   1e-07
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]            49   4e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       48   5e-05
gi|221219020 NYD-SP11 protein [Homo sapiens]                           48   7e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    48   7e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    48   7e-05
gi|17975763 myelin transcription factor 1 [Homo sapiens]               47   9e-05
gi|148746195 trichohyalin [Homo sapiens]                               47   9e-05
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap...    47   1e-04
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    47   1e-04
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    46   2e-04
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            46   2e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    46   3e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    46   3e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    46   3e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    46   3e-04
gi|21361639 DIPB protein [Homo sapiens]                                45   3e-04
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               45   4e-04
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [...    45   6e-04
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                44   7e-04
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    44   7e-04
gi|5453567 craniofacial development protein 1 [Homo sapiens]           44   7e-04
gi|28274705 family with sequence similarity 9, member A [Homo sa...    44   7e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    44   0.001
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    44   0.001
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    44   0.001
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    44   0.001
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]                  44   0.001

>gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo
            sapiens]
          Length = 1236

 Score = 2437 bits (6316), Expect = 0.0
 Identities = 1236/1236 (100%), Positives = 1236/1236 (100%)

Query: 1    MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN 60
            MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN
Sbjct: 1    MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN 60

Query: 61   ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA 120
            ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA
Sbjct: 61   ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA 120

Query: 121  HKEICAVLAAVTEVIRSQGGKETETEYFAALVLSCLATLLRKQDLEAWGYPVTLQVYHGL 180
            HKEICAVLAAVTEVIRSQGGKETETEYFAALVLSCLATLLRKQDLEAWGYPVTLQVYHGL
Sbjct: 121  HKEICAVLAAVTEVIRSQGGKETETEYFAALVLSCLATLLRKQDLEAWGYPVTLQVYHGL 180

Query: 181  LSFTVHPKPKIRKAAQHGVCSVLKGSEFMFEKAPAHHPAAISTAKFCIQEIEKSGGSKEA 240
            LSFTVHPKPKIRKAAQHGVCSVLKGSEFMFEKAPAHHPAAISTAKFCIQEIEKSGGSKEA
Sbjct: 181  LSFTVHPKPKIRKAAQHGVCSVLKGSEFMFEKAPAHHPAAISTAKFCIQEIEKSGGSKEA 240

Query: 241  TTTLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLSHVLVTACAMQAFHSLFHARPGLST 300
            TTTLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLSHVLVTACAMQAFHSLFHARPGLST
Sbjct: 241  TTTLHMLTLLKDLLPCFPEGLVKSCSETLLRVMTLSHVLVTACAMQAFHSLFHARPGLST 300

Query: 301  LSAELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQWDLGLGHLPRFFGTAV 360
            LSAELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQWDLGLGHLPRFFGTAV
Sbjct: 301  LSAELNAQIITALYDYVPSENDLQPLLAWLKVMEKAHINLVRLQWDLGLGHLPRFFGTAV 360

Query: 361  TCLLSPHSQVLTAATQSLKEILKECVAPHMADIGSVTSSASGPAQSVAKMFRAVEEGLTY 420
            TCLLSPHSQVLTAATQSLKEILKECVAPHMADIGSVTSSASGPAQSVAKMFRAVEEGLTY
Sbjct: 361  TCLLSPHSQVLTAATQSLKEILKECVAPHMADIGSVTSSASGPAQSVAKMFRAVEEGLTY 420

Query: 421  KFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTS 480
            KFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTS
Sbjct: 421  KFHAAWSSVLQLLCVFFEACGRQAHPVMRKCLQSLCDLRLSPHFPHTAALDQAVGAAVTS 480

Query: 481  MGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAM 540
            MGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAM
Sbjct: 481  MGPEVVLQAVPLEIDGSEETLDFPRSWLLPVIRDHVQETRLGFFTTYFLPLANTLKSKAM 540

Query: 541  DLAQAGSTVESKIYDTLQWQMWTLLPGFCTRPTDVAISFKGLARTLGMAISERPDLRVTV 600
            DLAQAGSTVESKIYDTLQWQMWTLLPGFCTRPTDVAISFKGLARTLGMAISERPDLRVTV
Sbjct: 541  DLAQAGSTVESKIYDTLQWQMWTLLPGFCTRPTDVAISFKGLARTLGMAISERPDLRVTV 600

Query: 601  CQALRTLITKGCQAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIRTYL 660
            CQALRTLITKGCQAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIRTYL
Sbjct: 601  CQALRTLITKGCQAEADRAEVSRFAKNFLPILFNLYGQPVAAGDTPAPRRAVLETIRTYL 660

Query: 661  TITDTQLVNSLLEKASEKVLDPASSDFTRLSVLDLVVALAPCADEAAISKLYSTIRPYLE 720
            TITDTQLVNSLLEKASEKVLDPASSDFTRLSVLDLVVALAPCADEAAISKLYSTIRPYLE
Sbjct: 661  TITDTQLVNSLLEKASEKVLDPASSDFTRLSVLDLVVALAPCADEAAISKLYSTIRPYLE 720

Query: 721  SKAHGVQKKAYRVLEEVCASPQGPGALFVQSHLEDLKKTLLDSLRSTSSPAKRPRLKCLL 780
            SKAHGVQKKAYRVLEEVCASPQGPGALFVQSHLEDLKKTLLDSLRSTSSPAKRPRLKCLL
Sbjct: 721  SKAHGVQKKAYRVLEEVCASPQGPGALFVQSHLEDLKKTLLDSLRSTSSPAKRPRLKCLL 780

Query: 781  HIVRKLSAEHKEFITALIPEVILCTKEVSVGARKNAFALLVEMGHAFLRFGSNQEEALQC 840
            HIVRKLSAEHKEFITALIPEVILCTKEVSVGARKNAFALLVEMGHAFLRFGSNQEEALQC
Sbjct: 781  HIVRKLSAEHKEFITALIPEVILCTKEVSVGARKNAFALLVEMGHAFLRFGSNQEEALQC 840

Query: 841  YLVLIYPGLVGAVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKS 900
            YLVLIYPGLVGAVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKS
Sbjct: 841  YLVLIYPGLVGAVTMVSCSILALTHLLFEFKGLMGTSTVEQLLENVCLLLASRTRDVVKS 900

Query: 901  ALGFIKVAVTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVK 960
            ALGFIKVAVTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVK
Sbjct: 901  ALGFIKVAVTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVK 960

Query: 961  RLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSE 1020
            RLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSE
Sbjct: 961  RLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSE 1020

Query: 1021 DEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK 1080
            DEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK
Sbjct: 1021 DEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK 1080

Query: 1081 KDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEA 1140
            KDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEA
Sbjct: 1081 KDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEA 1140

Query: 1141 EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKL 1200
            EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKL
Sbjct: 1141 EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKL 1200

Query: 1201 NRRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRRP 1236
            NRRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRRP
Sbjct: 1201 NRRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRRP 1236


>gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo
            sapiens]
          Length = 1297

 Score = 2141 bits (5548), Expect = 0.0
 Identities = 1085/1085 (100%), Positives = 1085/1085 (100%)

Query: 152  VLSCLATLLRKQDLEAWGYPVTLQVYHGLLSFTVHPKPKIRKAAQHGVCSVLKGSEFMFE 211
            VLSCLATLLRKQDLEAWGYPVTLQVYHGLLSFTVHPKPKIRKAAQHGVCSVLKGSEFMFE
Sbjct: 213  VLSCLATLLRKQDLEAWGYPVTLQVYHGLLSFTVHPKPKIRKAAQHGVCSVLKGSEFMFE 272

Query: 212  KAPAHHPAAISTAKFCIQEIEKSGGSKEATTTLHMLTLLKDLLPCFPEGLVKSCSETLLR 271
            KAPAHHPAAISTAKFCIQEIEKSGGSKEATTTLHMLTLLKDLLPCFPEGLVKSCSETLLR
Sbjct: 273  KAPAHHPAAISTAKFCIQEIEKSGGSKEATTTLHMLTLLKDLLPCFPEGLVKSCSETLLR 332

Query: 272  VMTLSHVLVTACAMQAFHSLFHARPGLSTLSAELNAQIITALYDYVPSENDLQPLLAWLK 331
            VMTLSHVLVTACAMQAFHSLFHARPGLSTLSAELNAQIITALYDYVPSENDLQPLLAWLK
Sbjct: 333  VMTLSHVLVTACAMQAFHSLFHARPGLSTLSAELNAQIITALYDYVPSENDLQPLLAWLK 392

Query: 332  VMEKAHINLVRLQWDLGLGHLPRFFGTAVTCLLSPHSQVLTAATQSLKEILKECVAPHMA 391
            VMEKAHINLVRLQWDLGLGHLPRFFGTAVTCLLSPHSQVLTAATQSLKEILKECVAPHMA
Sbjct: 393  VMEKAHINLVRLQWDLGLGHLPRFFGTAVTCLLSPHSQVLTAATQSLKEILKECVAPHMA 452

Query: 392  DIGSVTSSASGPAQSVAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKC 451
            DIGSVTSSASGPAQSVAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKC
Sbjct: 453  DIGSVTSSASGPAQSVAKMFRAVEEGLTYKFHAAWSSVLQLLCVFFEACGRQAHPVMRKC 512

Query: 452  LQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPV 511
            LQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPV
Sbjct: 513  LQSLCDLRLSPHFPHTAALDQAVGAAVTSMGPEVVLQAVPLEIDGSEETLDFPRSWLLPV 572

Query: 512  IRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFCTR 571
            IRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFCTR
Sbjct: 573  IRDHVQETRLGFFTTYFLPLANTLKSKAMDLAQAGSTVESKIYDTLQWQMWTLLPGFCTR 632

Query: 572  PTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITKGCQAEADRAEVSRFAKNFLPI 631
            PTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITKGCQAEADRAEVSRFAKNFLPI
Sbjct: 633  PTDVAISFKGLARTLGMAISERPDLRVTVCQALRTLITKGCQAEADRAEVSRFAKNFLPI 692

Query: 632  LFNLYGQPVAAGDTPAPRRAVLETIRTYLTITDTQLVNSLLEKASEKVLDPASSDFTRLS 691
            LFNLYGQPVAAGDTPAPRRAVLETIRTYLTITDTQLVNSLLEKASEKVLDPASSDFTRLS
Sbjct: 693  LFNLYGQPVAAGDTPAPRRAVLETIRTYLTITDTQLVNSLLEKASEKVLDPASSDFTRLS 752

Query: 692  VLDLVVALAPCADEAAISKLYSTIRPYLESKAHGVQKKAYRVLEEVCASPQGPGALFVQS 751
            VLDLVVALAPCADEAAISKLYSTIRPYLESKAHGVQKKAYRVLEEVCASPQGPGALFVQS
Sbjct: 753  VLDLVVALAPCADEAAISKLYSTIRPYLESKAHGVQKKAYRVLEEVCASPQGPGALFVQS 812

Query: 752  HLEDLKKTLLDSLRSTSSPAKRPRLKCLLHIVRKLSAEHKEFITALIPEVILCTKEVSVG 811
            HLEDLKKTLLDSLRSTSSPAKRPRLKCLLHIVRKLSAEHKEFITALIPEVILCTKEVSVG
Sbjct: 813  HLEDLKKTLLDSLRSTSSPAKRPRLKCLLHIVRKLSAEHKEFITALIPEVILCTKEVSVG 872

Query: 812  ARKNAFALLVEMGHAFLRFGSNQEEALQCYLVLIYPGLVGAVTMVSCSILALTHLLFEFK 871
            ARKNAFALLVEMGHAFLRFGSNQEEALQCYLVLIYPGLVGAVTMVSCSILALTHLLFEFK
Sbjct: 873  ARKNAFALLVEMGHAFLRFGSNQEEALQCYLVLIYPGLVGAVTMVSCSILALTHLLFEFK 932

Query: 872  GLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQLVMEAIGKL 931
            GLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQLVMEAIGKL
Sbjct: 933  GLMGTSTVEQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQLVMEAIGKL 992

Query: 932  SDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAA 991
            SDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAA
Sbjct: 993  SDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAA 1052

Query: 992  VEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG 1051
            VEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG
Sbjct: 1053 VEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG 1112

Query: 1052 GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK 1111
            GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK
Sbjct: 1113 GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK 1172

Query: 1112 GEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAE 1171
            GEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAE
Sbjct: 1173 GEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAE 1232

Query: 1172 YKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARRGSQVGHKNRR 1231
            YKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARRGSQVGHKNRR
Sbjct: 1233 YKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARRGSQVGHKNRR 1292

Query: 1232 KDRRP 1236
            KDRRP
Sbjct: 1293 KDRRP 1297



 Score =  301 bits (770), Expect = 3e-81
 Identities = 155/174 (89%), Positives = 161/174 (92%), Gaps = 1/174 (0%)

Query: 1   MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN 60
           MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN
Sbjct: 1   MGRSGKLPSGVSAKLKRWKKGHSSDSNPAICRHRQAARSRFFSRPSGRSDLTVDAVKLHN 60

Query: 61  ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA 120
           ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA
Sbjct: 61  ELQSGSLRLGKSEAPETPMEEEAELVLTEKSSGTFLSGLSDCTNVTFSKVQRFWESNSAA 120

Query: 121 HKEICAVLAAVTEVIRSQGGKETETEYFAALVLSCLATLLRKQDLEAWGYPVTL 174
           HKEICAVLAAVTEVIRSQGGKETETEYFAAL ++ +  +   + L A  Y + L
Sbjct: 121 HKEICAVLAAVTEVIRSQGGKETETEYFAAL-MTTMEAVESPESLAAVAYLLNL 173


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 66/243 (27%), Positives = 103/243 (42%), Gaps = 20/243 (8%)

Query: 993  EEEEEEEEEEEPAQGKGDSI-EEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG 1051
            EEE E E EEE  +GKG+   EE   + E+EE   E E   G+ + +           EG
Sbjct: 905  EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG 964

Query: 1052 GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGA- 1110
             G+E     + +  +     + G G G +++   +   +G     EE +G   EEEEG  
Sbjct: 965  EGEEEGEG-EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEG--EEEGEGEGEEEEEGEV 1021

Query: 1111 -------KGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVA 1163
                   +GE E   +  E+     +K  + +  +   EEE E   +YQ  G        
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE-----EE 1076

Query: 1164 KKAMPGAEY-KAKKAKGDVKKKGRPDPYAYIPLNRSKLN-RRKKMKLQGQFKGLVKAARR 1221
             +   G EY K  K KG V K G+   Y    +  ++ N + ++ K+  Q K L+K    
Sbjct: 1077 NERQDGEEYKKVSKIKGSV-KYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKNGPS 1135

Query: 1222 GSQ 1224
            GS+
Sbjct: 1136 GSK 1138



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 50/172 (29%), Positives = 82/172 (47%), Gaps = 18/172 (10%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034
            R+   + +R++ + +   EE  E EEEE      GD  EE   + E +E+ E EE    +
Sbjct: 715  REQGHQKERNQEMEEGGEEEHGEGEEEE------GDREEEEEKEGEGKEEGEGEEVEGER 768

Query: 1035 EQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLI 1094
            E+ +  R++     KE  G+E       +  Q     +   GRG +K+ G +V   G + 
Sbjct: 769  EKEEGERKKEERAGKEEKGEE-------EGDQGEGEEEETEGRGEEKEEGGEVEG-GEV- 819

Query: 1095 IREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELE 1146
              EE  G + EEEE  +GE+EE  +  E+     ++  + K ++E EE E E
Sbjct: 820  --EEGKGEREEEEEEGEGEEEE-GEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 17/122 (13%)

Query: 994  EEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGG 1053
            EE + E EEE  +G+G+  EE   + E+ E  EEE   +G+E+ +           EG G
Sbjct: 820  EEGKGEREEEEEEGEGEE-EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG 878

Query: 1054 DEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGE 1113
            +E                + G G G ++  G     +G     EE +G   EEE   KGE
Sbjct: 879  EE----------------EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE 922

Query: 1114 DE 1115
            +E
Sbjct: 923  EE 924



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 48/167 (28%), Positives = 68/167 (40%), Gaps = 19/167 (11%)

Query: 993  EEEEEEEE-EEEPAQGKGDSIEEILADSEDEEDNEEE-ERSRGKEQRKLARQRSRAWLKE 1050
            E EEEEEE E E  +G+G+  E    + E E   EEE E   G+E+ +           E
Sbjct: 825  EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884

Query: 1051 GGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGA 1110
            G G+E       +        + G G G +++   K   +G     EE +G   EEE   
Sbjct: 885  GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG-----EEGEGEGEEEEGEG 939

Query: 1111 KGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSG 1157
            +GED E     E+             + E EEEE E   + +  G G
Sbjct: 940  EGEDGEGEGEEEE------------GEWEGEEEEGEGEGEEEGEGEG 974



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 47/177 (26%), Positives = 81/177 (45%), Gaps = 23/177 (12%)

Query: 988  SQAAVEEEEEEEEEEEPAQGKGD-----SIEEILADSED--EEDNEEEERSRGKEQRKLA 1040
            S  A   ++EE E+ E  +G+G+       E+ LA+ E+  + D EE+E    +++R+  
Sbjct: 663  SSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQE----QKEREQG 718

Query: 1041 RQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSA-----DGRLII 1095
             Q+ R    E GG+E     + +   R    +   G G+++  G +V       +G    
Sbjct: 719  HQKERNQEMEEGGEEEHGEGEEEEGDRE-EEEEKEGEGKEEGEGEEVEGEREKEEGERKK 777

Query: 1096 REEADGNKMEEEEGAKGEDEEM------ADPMEDVIIRNKKHQKLKHQKEAEEEELE 1146
             E A   +  EEEG +GE EE        +  E   +   + ++ K ++E EEEE E
Sbjct: 778  EERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGE 834



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 37/162 (22%), Positives = 72/162 (44%), Gaps = 8/162 (4%)

Query: 993  EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGG 1052
            E+++   E E P +G+ +  E+      D E+ E++ER +G ++ +          + G 
Sbjct: 678  EKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGE 737

Query: 1053 GDEPLNFLDPKVAQRVLATQPGPGR----GRKKDHGFKVSAD--GRLIIREEA--DGNKM 1104
            G+E     + +  +     + G G      R+K+ G +   +  G+    EE    G   
Sbjct: 738  GEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE 797

Query: 1105 EEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELE 1146
            EEE   +GE++E    +E   +   K ++ + ++E E EE E
Sbjct: 798  EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 57/227 (25%), Positives = 92/227 (40%), Gaps = 61/227 (26%)

Query: 993  EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG--KEQRKLARQ--RSRAWL 1048
            EE E  EE+E     KG+ IEE     ++ E NEE  +  G  KE+ ++       +A +
Sbjct: 582  EEVEIPEEKEGAEDSKGNGIEE-----QEVEANEENVKVHGGRKEKTEILSDDLTDKAEV 636

Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGP-GRG----------------RKKDHGFKVSADG 1091
             EG             A+ V   + GP GRG                 +++ G K    G
Sbjct: 637  SEG------------KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRG 684

Query: 1092 RLIIREEADGNKMEEEEGAK--GEDEEMADPMEDVIIRNKKHQKLKHQK----------E 1139
             +    E +    E+EE  K  GE++E  +       R + HQK ++Q+          E
Sbjct: 685  EMERPGEGEKELAEKEEWKKRDGEEQEQKE-------REQGHQKERNQEMEEGGEEEHGE 737

Query: 1140 AEEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGR 1186
             EEEE +   + +  G G      ++     E + +K +G+ KK+ R
Sbjct: 738  GEEEEGDREEEEEKEGEGKEEGEGEE----VEGEREKEEGERKKEER 780


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 44/205 (21%), Positives = 96/205 (46%), Gaps = 9/205 (4%)

Query: 966  EYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDN 1025
            E  R+    +K     +  R   +   E+EE+  E+EE    + + ++E      ++E+ 
Sbjct: 3    EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62

Query: 1026 EEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGF 1085
              E+  +  EQ++L  Q+ + W +    DE L   + ++ ++ +  Q    R +KK    
Sbjct: 63   MWEQEEKMWEQQRLPEQKEKMWEQ----DERLREKEERMREQKMWQQVEKMREKKKTQEE 118

Query: 1086 KVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEEL 1145
            K+      +  +E +    E+EE  + ++E+M +  E +  + +K ++ + + + +EE++
Sbjct: 119  KMQEQEEKM--QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176

Query: 1146 E--IPPQYQAG-GSGIHRPVAKKAM 1167
                P   +AG GS    P A++ M
Sbjct: 177  RDVEPAGGEAGEGSPQDNPTAQEIM 201


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 55/248 (22%), Positives = 103/248 (41%), Gaps = 13/248 (5%)

Query: 993  EEEEEEEEEEEPAQGK-GDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEG 1051
            ++E+EEEEEE+P +G  G++  E++ + +  E  EE      K  +  + +  +   +E 
Sbjct: 187  DKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQ 246

Query: 1052 GGD-----EPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEE 1106
            G D     E +   D + A+   A      R R K    K  AD R  I  E      E 
Sbjct: 247  GSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQER 306

Query: 1107 EEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKA 1166
            E     E E M +  E+     ++ +  + +K A EE   I  + +       R   K+ 
Sbjct: 307  ERREAEERERMRE--EEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE--ERQRIKEE 362

Query: 1167 MPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARRGSQVG 1226
               A  + ++A+ + ++K + +          K +  ++ K++G+    V+    G  V 
Sbjct: 363  EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGE---KVEQKIEGKWVN 419

Query: 1227 HKNRRKDR 1234
             K  ++D+
Sbjct: 420  EKKAQEDK 427



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 45/181 (24%), Positives = 84/181 (46%), Gaps = 24/181 (13%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034
            R+AE R +R R   + A EE +  +EEE+ A  +   I+E    + +E    +EE  R  
Sbjct: 309  REAEER-ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA 367

Query: 1035 EQRKLAR--QRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092
            E+R+ AR  +  +A ++E   ++ L        ++  A Q    +G K +       +G+
Sbjct: 368  EERQRARAEEEEKAKVEEQKRNKQLE-------EKKHAMQETKIKGEKVEQ----KIEGK 416

Query: 1093 LIIREEADGNKME--------EEEGAK--GEDEEMADPMEDVIIRNKKHQKLKHQKEAEE 1142
             +  ++A  +K++        EE+G K   + E++ +          K +K+K  KE +E
Sbjct: 417  WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE 476

Query: 1143 E 1143
            E
Sbjct: 477  E 477


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 63/248 (25%), Positives = 102/248 (41%), Gaps = 41/248 (16%)

Query: 924  VMEAIGKLSDDMRRHFRMKL------RNLFTKFIRKFGFELVKRLLPE----EYHRVLVN 973
            +++A+ KL+ D R+  + ++      R LF K  R+   E  K  + E    E    L  
Sbjct: 2076 ILKALQKLTRDERKLTQEEIKMTKMKRALFVKE-RRLSIEQSKLDIKEWDFSEKRSELTK 2134

Query: 974  IRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEE---- 1029
              K  AR +R  A     +  +EE+  EEE    +  S  E++ D E+E   EEEE    
Sbjct: 2135 DEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHS--EVILDDEEEGGIEEEEVIPF 2192

Query: 1030 ----------RSRG-KEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRG 1078
                        RG K + K + Q      +E   +E  + LD    Q  L+++    R 
Sbjct: 2193 LKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEERE 2252

Query: 1079 RKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQK 1138
             +++             REE +  + EEE   + E EE     E+   + KK +K K + 
Sbjct: 2253 EEEE-------------REEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEV 2299

Query: 1139 EAEEEELE 1146
            + +EE  E
Sbjct: 2300 QEKEEVFE 2307



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 45/187 (24%), Positives = 86/187 (45%), Gaps = 25/187 (13%)

Query: 960  KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS--IEEILA 1017
            K+L  EE+ +V  N+  ++++ ++++   +  +EEE   E EE+  Q   +   I+E   
Sbjct: 1514 KKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHK 1573

Query: 1018 DSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGR 1077
             +         E+ R +E+RKLA++  +   +E      L   + K+AQ  +        
Sbjct: 1574 WARIHRKRARAEKKRAQEERKLAQEEEKLAQEE----RQLAQEERKLAQAYV-------- 1621

Query: 1078 GRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQ 1137
                    K++ D R +   +A+G   ++EE      E+++   E +  + KK  K K +
Sbjct: 1622 --------KITQDDREM--AQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAK-KWE 1670

Query: 1138 KEAEEEE 1144
            K A EEE
Sbjct: 1671 KVAREEE 1677



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 38/169 (22%), Positives = 75/169 (44%), Gaps = 13/169 (7%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034
            RK   R  + +    + V+E E EE   E  +   D +E+  + S +EE+  EEE  R +
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREE 2259

Query: 1035 EQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLI 1094
            E+    R+      +E  G+E          ++V   +    + +K+    +V     + 
Sbjct: 2260 EE---VREEEEERKEEEEGEE----------KQVEKEEEEKKKKKKEKKKEEVQEKEEVF 2306

Query: 1095 IREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEE 1143
              +E   ++ E E  +  E+EE +  +E+ + R K+  K + Q + +E+
Sbjct: 2307 EEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ 2355



 Score = 38.9 bits (89), Expect = 0.031
 Identities = 50/214 (23%), Positives = 95/214 (44%), Gaps = 26/214 (12%)

Query: 960  KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019
            +R + EE+    ++ ++A A  KR +   + A EEE+  +EE + AQ +    +  +  +
Sbjct: 1565 QRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKIT 1624

Query: 1020 EDEED----------NEEEERSRG----KEQRKLARQR---SRAWLKEGGGDEPLNFLDP 1062
            +D+ +           EE    RG    +E  KLA++R   ++ W K    +E L     
Sbjct: 1625 QDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGG 1684

Query: 1063 KVAQ--RVLA--TQPGPGRGRKKDHGFKVSADGRLIIREEAD-----GNKMEEEEGAKGE 1113
            K+A+   +LA   +  P R +  D   K  A     +  + +       ++ +EEG   E
Sbjct: 1685 KLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVE 1744

Query: 1114 DEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEI 1147
            +++     E+ +   ++    +  K A+EEEL I
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEEELLI 1778



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 28/83 (33%), Positives = 40/83 (48%), Gaps = 11/83 (13%)

Query: 965  EEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEE------EEEEEPAQGKGDSI---EEI 1015
            EE  R    +R+ E   K      +  VE+EEEE      E+++E  Q K +     EEI
Sbjct: 2253 EEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEI 2312

Query: 1016 LADSEDE--EDNEEEERSRGKEQ 1036
            +++ E E   D EEEE S   E+
Sbjct: 2313 MSEEETESLSDEEEEEESCSLEE 2335



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 22/72 (30%), Positives = 37/72 (51%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034
            +K +   K+     +  V EE+EE   EE  +   D  EE  + S +EE + E+E  + +
Sbjct: 2288 KKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKE 2347

Query: 1035 EQRKLARQRSRA 1046
            +Q KL  QR ++
Sbjct: 2348 KQFKLQEQRRKS 2359



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 38/179 (21%), Positives = 78/179 (43%), Gaps = 9/179 (5%)

Query: 993  EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGG 1052
            ++EE++  ++ P QG+  ++++     + + +  +EER   +E  ++A    +   +EG 
Sbjct: 1389 KKEEKKTFQKSPKQGR-KAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGK 1447

Query: 1053 G---DEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEA---DGNKMEE 1106
                +   ++ D K A      +   G  RK    +K   + RL+  EE     G K+  
Sbjct: 1448 LVMIERTPSWQDWKKAWD--EWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSP 1505

Query: 1107 EEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKK 1165
            EE    ED+++       +  N    K K Q+  +EEE+ +  +    G    + V ++
Sbjct: 1506 EEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEE 1564


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
            sapiens]
          Length = 916

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 59/253 (23%), Positives = 113/253 (44%), Gaps = 46/253 (18%)

Query: 989  QAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWL 1048
            +AA E+EEE E EEE    K   ++    + ++EE  +EEE   G+E+ +   + +++  
Sbjct: 490  EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEE--EGQEEEEEEDEGAKSDQ 547

Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE 1108
             E GG E     + +              G +++   +  A+G     EEA+    +EE+
Sbjct: 548  AEEGGSEKEGSSEKE-------------EGEQEEGETEAEAEG-----EEAEA---KEEK 586

Query: 1109 GAKGEDEEMADPME---DVIIRNKKHQKLKHQKEAEEEELEIP----PQYQAGGSGIHR- 1160
              + + EE+A   E   D  +   +  K    K   EE+ + P    P  + G S + + 
Sbjct: 587  KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 646

Query: 1161 PVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAAR 1220
            PV +K       K+   K  V++KG+       P+++S +  + K  +    K  V+ A+
Sbjct: 647  PVEEKG------KSPVPKSPVEEKGKS------PVSKSPVEEKAKSPVP---KSPVEEAK 691

Query: 1221 RGSQVGHKNRRKD 1233
              ++VG   ++++
Sbjct: 692  SKAEVGKGEQKEE 704



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 70/284 (24%), Positives = 115/284 (40%), Gaps = 57/284 (20%)

Query: 993  EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG-------------KEQRKL 1039
            EEE +EEEEEE    K D  EE  ++ E   + EE E+  G             KE++K+
Sbjct: 529  EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 588

Query: 1040 ARQRSRAWLKEG-GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREE 1098
              +      KE    D  +    P+ A+  +   P   +G+       V   G+  + + 
Sbjct: 589  EEKSEEVATKEELVADAKVE--KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 646

Query: 1099 ADGNKME--------EEEG----AKGEDEEMA------DPMEDVIIRNKKHQKLKHQKEA 1140
                K +        EE+G    +K   EE A       P+E+   ++K       QKE 
Sbjct: 647  PVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEA--KSKAEVGKGEQKEE 704

Query: 1141 EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRS-K 1199
            EE+E++  P+ +       +   K+  P    + KKA+  VK++   +    + + +S K
Sbjct: 705  EEKEVKEAPKEE-------KVEKKEEKPKDVPEKKKAESPVKEEAVAE---VVTITKSVK 754

Query: 1200 LNRRKKMKLQG----QFKGLVKAA------RRGSQVGHKNRRKD 1233
            ++  K+ K +G    Q K   KA         GS  G K  RK+
Sbjct: 755  VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKE 798



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 51/215 (23%), Positives = 90/215 (41%), Gaps = 23/215 (10%)

Query: 978  EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037
            E  AK+    + A   +EEE E+EEE  Q + +  +E     + EE   E+E S  KE+ 
Sbjct: 505  EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG 564

Query: 1038 KLARQRSRAWLKEGGGDEPLNFLDPKVAQR--VLATQPGPGRGRKKDHGFKVSADGRLII 1095
            +     + A   E  G+E     + KV ++   +AT+             ++ AD ++  
Sbjct: 565  EQEEGETEA---EAEGEEAEAKEEKKVEEKSEEVATKE------------ELVADAKVEK 609

Query: 1096 REEADGNKMEEEEGAKGEDEEMADPMED----VIIRNKKHQKLKH--QKEAEEEELEIPP 1149
             E+A     +     KG+      P+E+     + ++   +K K    K   EE+ + P 
Sbjct: 610  PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 669

Query: 1150 QYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKK 1184
                       PV K  +  A+ KA+  KG+ K++
Sbjct: 670  SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 704



 Score = 33.9 bits (76), Expect = 0.99
 Identities = 36/190 (18%), Positives = 82/190 (43%), Gaps = 33/190 (17%)

Query: 964  PEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEE---EEPAQGKGDS------IEE 1014
            P E  +    + K E + +  + + +A  EE+ E++EE   + P + K +S      + E
Sbjct: 686  PVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAE 745

Query: 1015 ILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPG 1074
            ++  ++  + + E+E     +  +  +++ +A   EGG +E               +  G
Sbjct: 746  VVTITKSVKVHLEKETKEEGKPLQQEKEKEKAG-GEGGSEEE-------------GSDKG 791

Query: 1075 PGRGRKKDHGFKVSADGRLIIREEA--DGNKMEEEEG--------AKGEDEEMADPMEDV 1124
                RK+D       +G+  + +E    G+  EEE+G        +  ++++  D  E+ 
Sbjct: 792  AKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEK 851

Query: 1125 IIRNKKHQKL 1134
            ++  K  +K+
Sbjct: 852  VVVTKTVEKI 861



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 28/185 (15%)

Query: 974  IRKAEARAKRHRALSQAAVEEEEE--------EEEEEEPAQGKGDSIEEILADSEDEEDN 1025
            + K+    K    +S++ VEE+ +        EE + +   GKG+  EE   + E +E  
Sbjct: 656  VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE--EEKEVKEAP 713

Query: 1026 EEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK--KDH 1083
            +EE+  + +E+ K   ++ +A       + P+   +  VA+ V  T+       K  K+ 
Sbjct: 714  KEEKVEKKEEKPKDVPEKKKA-------ESPVK--EEAVAEVVTITKSVKVHLEKETKEE 764

Query: 1084 GFKVSADGRLIIREEADGNKMEEEEG----AKGEDEEMADPMEDVIIRNKKHQKLKHQKE 1139
            G  +  +     +E+A G    EEEG    AKG  +E      +V  + +  Q+ K +  
Sbjct: 765  GKPLQQEKE---KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS 821

Query: 1140 AEEEE 1144
              EEE
Sbjct: 822  GREEE 826


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
            sapiens]
          Length = 540

 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 59/253 (23%), Positives = 113/253 (44%), Gaps = 46/253 (18%)

Query: 989  QAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWL 1048
            +AA E+EEE E EEE    K   ++    + ++EE  +EEE   G+E+ +   + +++  
Sbjct: 114  EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEE--EGQEEEEEEDEGAKSDQ 171

Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE 1108
             E GG E     + +              G +++   +  A+G     EEA+    +EE+
Sbjct: 172  AEEGGSEKEGSSEKE-------------EGEQEEGETEAEAEG-----EEAEA---KEEK 210

Query: 1109 GAKGEDEEMADPME---DVIIRNKKHQKLKHQKEAEEEELEIP----PQYQAGGSGIHR- 1160
              + + EE+A   E   D  +   +  K    K   EE+ + P    P  + G S + + 
Sbjct: 211  KVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 270

Query: 1161 PVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAAR 1220
            PV +K       K+   K  V++KG+       P+++S +  + K  +    K  V+ A+
Sbjct: 271  PVEEKG------KSPVPKSPVEEKGKS------PVSKSPVEEKAKSPVP---KSPVEEAK 315

Query: 1221 RGSQVGHKNRRKD 1233
              ++VG   ++++
Sbjct: 316  SKAEVGKGEQKEE 328



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 70/284 (24%), Positives = 115/284 (40%), Gaps = 57/284 (20%)

Query: 993  EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG-------------KEQRKL 1039
            EEE +EEEEEE    K D  EE  ++ E   + EE E+  G             KE++K+
Sbjct: 153  EEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKV 212

Query: 1040 ARQRSRAWLKEG-GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREE 1098
              +      KE    D  +    P+ A+  +   P   +G+       V   G+  + + 
Sbjct: 213  EEKSEEVATKEELVADAKVE--KPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 270

Query: 1099 ADGNKME--------EEEG----AKGEDEEMA------DPMEDVIIRNKKHQKLKHQKEA 1140
                K +        EE+G    +K   EE A       P+E+   ++K       QKE 
Sbjct: 271  PVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEA--KSKAEVGKGEQKEE 328

Query: 1141 EEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRS-K 1199
            EE+E++  P+ +       +   K+  P    + KKA+  VK++   +    + + +S K
Sbjct: 329  EEKEVKEAPKEE-------KVEKKEEKPKDVPEKKKAESPVKEEAVAE---VVTITKSVK 378

Query: 1200 LNRRKKMKLQG----QFKGLVKAA------RRGSQVGHKNRRKD 1233
            ++  K+ K +G    Q K   KA         GS  G K  RK+
Sbjct: 379  VHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKE 422



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 51/215 (23%), Positives = 90/215 (41%), Gaps = 23/215 (10%)

Query: 978  EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037
            E  AK+    + A   +EEE E+EEE  Q + +  +E     + EE   E+E S  KE+ 
Sbjct: 129  EVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG 188

Query: 1038 KLARQRSRAWLKEGGGDEPLNFLDPKVAQR--VLATQPGPGRGRKKDHGFKVSADGRLII 1095
            +     + A   E  G+E     + KV ++   +AT+             ++ AD ++  
Sbjct: 189  EQEEGETEA---EAEGEEAEAKEEKKVEEKSEEVATKE------------ELVADAKVEK 233

Query: 1096 REEADGNKMEEEEGAKGEDEEMADPMED----VIIRNKKHQKLKH--QKEAEEEELEIPP 1149
             E+A     +     KG+      P+E+     + ++   +K K    K   EE+ + P 
Sbjct: 234  PEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 293

Query: 1150 QYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKK 1184
                       PV K  +  A+ KA+  KG+ K++
Sbjct: 294  SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE 328



 Score = 33.9 bits (76), Expect = 0.99
 Identities = 36/190 (18%), Positives = 82/190 (43%), Gaps = 33/190 (17%)

Query: 964  PEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEE---EEPAQGKGDS------IEE 1014
            P E  +    + K E + +  + + +A  EE+ E++EE   + P + K +S      + E
Sbjct: 310  PVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAE 369

Query: 1015 ILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPG 1074
            ++  ++  + + E+E     +  +  +++ +A   EGG +E               +  G
Sbjct: 370  VVTITKSVKVHLEKETKEEGKPLQQEKEKEKAG-GEGGSEEE-------------GSDKG 415

Query: 1075 PGRGRKKDHGFKVSADGRLIIREEA--DGNKMEEEEG--------AKGEDEEMADPMEDV 1124
                RK+D       +G+  + +E    G+  EEE+G        +  ++++  D  E+ 
Sbjct: 416  AKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEK 475

Query: 1125 IIRNKKHQKL 1134
            ++  K  +K+
Sbjct: 476  VVVTKTVEKI 485



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 45/185 (24%), Positives = 81/185 (43%), Gaps = 28/185 (15%)

Query: 974  IRKAEARAKRHRALSQAAVEEEEE--------EEEEEEPAQGKGDSIEEILADSEDEEDN 1025
            + K+    K    +S++ VEE+ +        EE + +   GKG+  EE   + E +E  
Sbjct: 280  VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEE--EEKEVKEAP 337

Query: 1026 EEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK--KDH 1083
            +EE+  + +E+ K   ++ +A       + P+   +  VA+ V  T+       K  K+ 
Sbjct: 338  KEEKVEKKEEKPKDVPEKKKA-------ESPVK--EEAVAEVVTITKSVKVHLEKETKEE 388

Query: 1084 GFKVSADGRLIIREEADGNKMEEEEG----AKGEDEEMADPMEDVIIRNKKHQKLKHQKE 1139
            G  +  +     +E+A G    EEEG    AKG  +E      +V  + +  Q+ K +  
Sbjct: 389  GKPLQQEKE---KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS 445

Query: 1140 AEEEE 1144
              EEE
Sbjct: 446  GREEE 450


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 25/64 (39%), Positives = 37/64 (57%)

Query: 977  AEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQ 1036
            +E  +K+   LS    +EEEEEEEEEE    + +  EE   + E+EE+ EEEE    +E+
Sbjct: 245  SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304

Query: 1037 RKLA 1040
             + A
Sbjct: 305  EEAA 308



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 22/64 (34%), Positives = 36/64 (56%)

Query: 977  AEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQ 1036
            A   + + + +     E+EEEEEEEEE  + + +  EE   + E+EE+ EEEE    +E+
Sbjct: 244  ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303

Query: 1037 RKLA 1040
             + A
Sbjct: 304  EEEA 307



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 20/61 (32%), Positives = 33/61 (54%)

Query: 978  EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037
            E  A    +  +  +  EEE+EEEEE  + + +  EE   + E+EE+ EEEE    +E+ 
Sbjct: 241  EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300

Query: 1038 K 1038
            +
Sbjct: 301  E 301



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 36/167 (21%), Positives = 67/167 (40%), Gaps = 30/167 (17%)

Query: 987  LSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRA 1046
            L+   + EE   EE+   A   G  I  +L ++ +   +EE E+                
Sbjct: 169  LNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGL-------------- 214

Query: 1047 WLKEGGGDEPLNFLDPKVAQRVLATQPGPGRG----RKKDHGFKVSADGRLIIREEADGN 1102
                        F+ P+ A+ V+       +       +D   + S+  + I+  E +  
Sbjct: 215  ------------FIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262

Query: 1103 KMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPP 1149
            + EEEE  + EDEE  +  E+     ++ ++ + ++E EEEE E  P
Sbjct: 263  EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309



 Score = 33.9 bits (76), Expect = 0.99
 Identities = 18/45 (40%), Positives = 23/45 (51%)

Query: 993  EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037
            EEEEEEEEEEE  + + +  EE   D   +ED       +  E R
Sbjct: 285  EEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELR 329


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 49/272 (18%), Positives = 122/272 (44%), Gaps = 33/272 (12%)

Query: 978  EARAKRHRALSQAAVEE----------EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEE 1027
            E + +RH   ++ A++E          EEEEE + E  + +    +E     E++   EE
Sbjct: 881  ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940

Query: 1028 EERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFK- 1086
            E+  R + +++  ++R R + K    D+ L     +  +++L  +P   R ++++  ++ 
Sbjct: 941  EQLLREEREKRRRQERERQYRK----DKKLQ----QKEEQLLGEEPEKRRRQEREKKYRE 992

Query: 1087 ---VSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEE 1143
               +  +   ++REE +  + +E E    + +E+    E ++   ++ ++L+ ++    E
Sbjct: 993  EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052

Query: 1144 ELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRR 1203
            E E+  Q +    G  R   ++     +Y+ ++     +++          L R +  +R
Sbjct: 1053 EEEL-QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ----------LLREEPEKR 1101

Query: 1204 KKMKLQGQFKGLVKAARRGSQVGHKNRRKDRR 1235
            ++ + + Q +   +  +   Q+  + R K RR
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREKRRR 1133



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 59/266 (22%), Positives = 116/266 (43%), Gaps = 41/266 (15%)

Query: 976  KAEARAKRHRALSQAAVEEEEE--EEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG 1033
            + E   KR R  +     EEE+  +E EE+P + +    E      E+E  ++E+ R   
Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ----ERDRKFREEELRHQEQGRKFL 1377

Query: 1034 KEQRKLARQ-RSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092
            +E+++L RQ R R +LKE               ++ L  Q    + R+ D   K   + +
Sbjct: 1378 EEEQRLRRQERERKFLKE---------------EQQLRCQEREQQLRQ-DRDRKFREEEQ 1421

Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQ 1152
             + R+E D    EEE+  + ++ E     E+  +R ++H+K + +++  +E  E      
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE------ 1475

Query: 1153 AGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGR----PDPYAYIPLNRSKLNRRKKMKL 1208
                 +HR    +     E + ++ + D K + +     +P         +L+R+++ + 
Sbjct: 1476 ---QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532

Query: 1209 QGQFKGLVKAARRGSQVGHKNRRKDR 1234
              Q +  ++   RG Q     RR+DR
Sbjct: 1533 FLQEEQQLRRQERGQQ-----RRQDR 1553



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 43/187 (22%), Positives = 85/187 (45%), Gaps = 15/187 (8%)

Query: 960  KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019
            ++LL EE  +     R+ + R K++R   +   EEE+   EE E  + +     E     
Sbjct: 971  EQLLGEEPEK-----RRRQEREKKYREEEELQQEEEQLLREEREKRRRQE---WERQYRK 1022

Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGR 1079
            +DE   EEE+  R + +++  ++R R + +E    E L   + ++      T+      R
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREE----EELQQEEEQLLGEERETRRRQELER 1078

Query: 1080 KKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVI---IRNKKHQKLKH 1136
            +     ++  +   ++REE +  + +E E    E+EE+    E ++      ++ Q+L+ 
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELER 1138

Query: 1137 QKEAEEE 1143
            Q   EEE
Sbjct: 1139 QYREEEE 1145



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 39/182 (21%), Positives = 80/182 (43%), Gaps = 30/182 (16%)

Query: 960  KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019
            +R LPEE         K + R +R     +    EEEE+ +  E AQ             
Sbjct: 808  QRFLPEEEE-------KEQRRRQRREREKELQFLEEEEQLQRRERAQ-----------QL 849

Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGR 1079
            ++EED  +E++ R + Q +   Q+ R  L+E          + K  +  L  +P      
Sbjct: 850  QEEEDGLQEDQERRRSQEQRRDQKWRWQLEE----------ERKRRRHTLYAKPALQEQL 899

Query: 1080 KKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKE 1139
            +K+    +  +   + REE +  + +E+E    E+E++    E+ ++R ++ ++ + ++E
Sbjct: 900  RKEQQL-LQEEEEELQREEREKRRRQEQERQYREEEQLQQE-EEQLLREEREKRRRQERE 957

Query: 1140 AE 1141
             +
Sbjct: 958  RQ 959



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 44/190 (23%), Positives = 86/190 (45%), Gaps = 13/190 (6%)

Query: 960  KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019
            ++LL EE   +    R+   R ++ R   +    ++EEE+   E  + K    E      
Sbjct: 903  QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE-KRRRQERERQYR 961

Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKV---AQRVLATQPGPG 1076
            +D++  ++EE+  G+E  K  RQ      +E   +E L   + ++    +     Q    
Sbjct: 962  KDKKLQQKEEQLLGEEPEKRRRQEREKKYRE---EEELQQEEEQLLREEREKRRRQEWER 1018

Query: 1077 RGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVI---IRNKKHQK 1133
            + RKKD   ++  +   ++REE +  +++E E    E+EE+    E ++      ++ Q+
Sbjct: 1019 QYRKKD---ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075

Query: 1134 LKHQKEAEEE 1143
            L+ Q   EEE
Sbjct: 1076 LERQYRKEEE 1085



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 36/172 (20%), Positives = 80/172 (46%), Gaps = 13/172 (7%)

Query: 978  EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037
            + R ++ R   Q    +E+E +  E+  Q +    ++ L    D +  E+E+  + +E++
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634

Query: 1038 KLARQ-RSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRK--KDHGFKVSADGRLI 1094
            +L RQ R R +L+E          +P++ ++    Q    R RK  ++       + + +
Sbjct: 1635 QLHRQERDRKFLEE----------EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQL 1684

Query: 1095 IREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELE 1146
             R+E D    EEE+  + ++ E     E+  +R ++ ++   ++E   +E E
Sbjct: 1685 RRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 41/188 (21%), Positives = 90/188 (47%), Gaps = 10/188 (5%)

Query: 963  LPEEYHRVLVNIRKAEARAKRHRALSQ-AAVEEEEEEEEEEEPAQGKGDSIEEILADSED 1021
            L +E  ++L   R+   R +R R   +   ++++EE+   EEP + +    E+     E+
Sbjct: 936  LQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK--KYREE 993

Query: 1022 EEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKK 1081
            EE  +EEE+   +E+ K  RQ    W ++    + L   + ++ +     +    R R+ 
Sbjct: 994  EELQQEEEQLLREEREKRRRQE---WERQYRKKDELQQEEEQLLREEREKRRLQERERQY 1050

Query: 1082 DHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKE-- 1139
                ++  +   ++ EE +  + +E E    ++EE+    E+ ++R +  ++ + ++E  
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE-EEQLLREEPEKRRRQERERQ 1109

Query: 1140 -AEEEELE 1146
              EEEEL+
Sbjct: 1110 CREEEELQ 1117



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 51/274 (18%), Positives = 110/274 (40%), Gaps = 29/274 (10%)

Query: 963  LPEEYHRVLVNIRKAEARAKRHRAL-SQAAVEEEEEEEEEEEPAQGKGDSIEEILADSED 1021
            L +E  ++L   R+   R +  R    +  V++EEE+   EEP + +   +E      E+
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER--QYREE 1173

Query: 1022 EEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKK 1081
            EE  +EEE+   +EQ K  ++R R + +E                  L  Q    R R +
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREE----------------EELQRQKRKQRYRDE 1217

Query: 1082 DHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE 1141
            D      +D +     E +    + +   KG + E    +ED  +R+++ Q+       E
Sbjct: 1218 DQ----RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273

Query: 1142 EEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLN 1201
            ++E +   + +            +  P  E   ++ + + K++ R        L   +  
Sbjct: 1274 QQERDREQERRRWQQ------RDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327

Query: 1202 RRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRR 1235
            +R++ +   +F+   +  +   +   + + +DR+
Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 62/265 (23%), Positives = 114/265 (43%), Gaps = 32/265 (12%)

Query: 916  HLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIR 975
            H  KH Q   E   K   + RR + +K      +  ++   + +KR   EE     + + 
Sbjct: 434  HEQKHEQERREQRLKREQEERRDW-LKREEETERHEQERRKQQLKRDQEEERRERWLKLE 492

Query: 976  KAEARAKRHRALSQAAVEEEEEEE------EEEEPAQGKGDSIEEILADSEDEEDNEEEE 1029
            + E R ++ R   Q   E+EE  E      EEEE  Q +  S +++      E++   E+
Sbjct: 493  EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL----RREQEERREQ 548

Query: 1030 RSRGKEQRKLARQRSRAWLK---EGGGDEPLNFLDPKVAQRVLATQPGPGRGR-KKDHGF 1085
              + +E+++L ++R    LK   E   D+ L   + +  QR+   Q      R K++   
Sbjct: 549  LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608

Query: 1086 KVSADGR---LIIREEADGN------KMEEEEGAKGED--EEMADPMEDVIIRNKKHQKL 1134
            ++  + R    + REE +        K EE+E  + +    E  +  E  + R ++ ++L
Sbjct: 609  RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL 668

Query: 1135 ------KHQKEAEEEELEIPPQYQA 1153
                  +H++E  E+EL    Q QA
Sbjct: 669  EQRLKREHEEERREQELAEEEQEQA 693



 Score = 38.1 bits (87), Expect = 0.052
 Identities = 37/186 (19%), Positives = 81/186 (43%), Gaps = 14/186 (7%)

Query: 963  LPEEYHRVLVNIRKAEARAKRHRAL-SQAAVEEEEEEEEEEEPAQGKGDSIEEILADSED 1021
            L +E  ++L   R+   R +  R    +  +++EEE+   EEP + +    E    + E+
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE-EE 1114

Query: 1022 EEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKK 1081
            E   EEE+  R + +++  ++  R + +E    +          +++L  +P   R ++ 
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQE--------EEQLLREEPEKRRRQEL 1166

Query: 1082 DHGFK----VSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQ 1137
            +  ++    +  +   ++REE +  + E E   + E+E      +       +   LK Q
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQ 1226

Query: 1138 KEAEEE 1143
             E E+E
Sbjct: 1227 WEPEKE 1232



 Score = 37.7 bits (86), Expect = 0.068
 Identities = 44/189 (23%), Positives = 83/189 (43%), Gaps = 16/189 (8%)

Query: 971  LVNIRKAEARAKRHRALSQAAVEE------EEEEEEEEEPAQGKGDSIEEILADSEDEED 1024
            L+  R+ E   +R     +   EE      ++ +E+E E A+G+  S ++   +  D + 
Sbjct: 109  LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168

Query: 1025 NEEE-ERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLD-PKVAQRVLATQPGPGRGRKKD 1082
             +EE  R R + Q +  R+     L+   G E   F D  ++ +R L      GR  K+ 
Sbjct: 169  RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ 228

Query: 1083 HGFKVSADGRLIIREEADGNKME-----EEEGAKGEDEEMADPM--EDVIIRNKKHQKLK 1135
               +   D      EE +  K E     EEE  + E+ +    +  E+  +R  + Q+L+
Sbjct: 229  QR-RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR 287

Query: 1136 HQKEAEEEE 1144
             +++ EE++
Sbjct: 288  RERQEEEQQ 296



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 38/178 (21%), Positives = 76/178 (42%), Gaps = 21/178 (11%)

Query: 976  KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILAD-SEDEEDNEEEERSRGK 1034
            + E + +R + L +   EE  E++ E+E  + +    +E   D  + EE+ E  E+ R K
Sbjct: 414  RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473

Query: 1035 EQ--RKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092
            +Q  R    +R   WLK       L   + +  Q     Q    +  +++   K   +  
Sbjct: 474  QQLKRDQEEERRERWLK-------LEEEERREQQERREQQLRREQEERREQRLKRQEE-- 524

Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPM-----EDVIIRNKKHQKLKHQKEAEEEEL 1145
                EE    ++  E+  + E EE  + +     E  + + ++ Q+LK ++E   ++L
Sbjct: 525  ----EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 43/199 (21%), Positives = 87/199 (43%), Gaps = 13/199 (6%)

Query: 957  ELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEIL 1016
            E +++L  +E  R      + + R +R + L +   EE  E++EE    Q + +  EE  
Sbjct: 276  EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR 335

Query: 1017 ADS---EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQP 1073
                  E EE  E++ R   +E+R+   Q+ R   +E   ++ L        ++ L  + 
Sbjct: 336  EQQLRREQEERREQQLRREQEEERR--EQQLRREQEEERREQQLRREQQLRREQQLRREQ 393

Query: 1074 GPGRGRKKDHGFKVSADGRL----IIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNK 1129
               R ++     ++  + +L     +R E    + +EEE  + E +   +  E  + R +
Sbjct: 394  QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE--RHEQKHEQERREQRLKREQ 451

Query: 1130 KHQK--LKHQKEAEEEELE 1146
            + ++  LK ++E E  E E
Sbjct: 452  EERRDWLKREEETERHEQE 470



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 39/179 (21%), Positives = 74/179 (41%), Gaps = 24/179 (13%)

Query: 969  RVLVNIRKA---EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDN 1025
            R L+ +R+    E + +R     +   EEEE+E  + E    K +   +        E  
Sbjct: 213  RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272

Query: 1026 EEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGF 1085
            EEEE+ R  E+++L R+R                 + +  QR+   Q      RK++   
Sbjct: 273  EEEEQLRKLERQELRRERQE---------------EEQQQQRLRREQQ---LRRKQEEER 314

Query: 1086 KVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144
            +   + R   RE+ +  + +EE   +    E  +  E  + R ++ ++ + Q   E+EE
Sbjct: 315  REQQEER---REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 37/192 (19%), Positives = 87/192 (45%), Gaps = 11/192 (5%)

Query: 974  IRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGD------SIEEILADSEDEE-DNE 1026
            +++ E +    +   +  +EEE +   +E   Q + D        E++L + E+++   +
Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ 1687

Query: 1027 EEERSRGKEQRKLARQ-RSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGF 1085
            E +R   +E+++L RQ R R +L+E               +  L  +    + R+++   
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR 1747

Query: 1086 KVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKE---AEE 1142
            K+  + +L    E    + +E +    E+E++    E+  +R+++  +   ++E    E 
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807

Query: 1143 EELEIPPQYQAG 1154
            EE ++ PQ + G
Sbjct: 1808 EEQQLRPQQRDG 1819



 Score = 35.0 bits (79), Expect = 0.44
 Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 12/97 (12%)

Query: 965  EEYHRVLVNIRKAEARAKRHRALSQAAVEEEEE------------EEEEEEPAQGKGDSI 1012
            +E+ +    +RK E + +      Q  ++EEEE            E +EEE  Q +    
Sbjct: 244  KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303

Query: 1013 EEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLK 1049
            +++    E+E   ++EER   +E+R+   +R    L+
Sbjct: 304  QQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 45/226 (19%), Positives = 89/226 (39%), Gaps = 23/226 (10%)

Query: 925  MEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRH 984
            +E   +L  +  R FR + + L  +  ++   +   R   EE  ++    R  + R +  
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508

Query: 985  RALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRS 1044
            R+        EEE++   +  Q K    E+ L   E  +   ++   + +E+ +L ++R 
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568

Query: 1045 RAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKM 1104
               L     D      + KV              R+++   K   D + + R+E      
Sbjct: 1569 EQQLSRQERDRKFRLEEQKV--------------RRQEQERKFMEDEQQLRRQEGQQQLR 1614

Query: 1105 EEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQ 1150
            +E +    EDE++    E+        Q+L H++E + + LE  PQ
Sbjct: 1615 QERDRKFREDEQLLQEREE--------QQL-HRQERDRKFLEEEPQ 1651



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 38/175 (21%), Positives = 77/175 (44%), Gaps = 16/175 (9%)

Query: 978  EARAKRHRALSQAA-VEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQ 1036
            E   + HR   Q   ++EE++   +E   Q + D   +   + +  ++ EE++ SR +  
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578

Query: 1037 RK--LARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLI 1094
            RK  L  Q+ R   +E    E    L  +  Q+ L  +    R  ++D       + + +
Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE--RDRKFREDEQLLQEREEQQL 1636

Query: 1095 IREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQ----KEAEEEEL 1145
             R+E D   +EEE   + ++ E         +R+ + +K + +    +E EE++L
Sbjct: 1637 HRQERDRKFLEEEPQLRRQEREQQ-------LRHDRDRKFREEEQLLQEGEEQQL 1684



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 45/211 (21%), Positives = 87/211 (41%), Gaps = 23/211 (10%)

Query: 978  EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037
            E +  R + L +   EEE+  +E E+    + +   +IL + +   + EE++  R +  R
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771

Query: 1038 K------LARQRSRAWLKEGGGDEPL---NFLDPKVAQRVLATQPGPGRGRKKDHGFKVS 1088
            K      L ++R    L+    D        L  +  ++ L  Q   G+ R ++   ++ 
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831

Query: 1089 ADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIP 1148
               +  +R+E D     EE+ A  E        E+  +  ++ QK + ++E +  E  I 
Sbjct: 1832 EQEQR-LRQERDRQYRAEEQFATQEKSR----REEQELWQEEEQKRRQERERKLREEHIR 1886

Query: 1149 PQYQAGGSGIHRPVAKKAMPGAEYKAKKAKG 1179
             Q +      HR V        E K+++ KG
Sbjct: 1887 RQQKE--EQRHRQV-------GEIKSQEGKG 1908



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 46/215 (21%), Positives = 94/215 (43%), Gaps = 13/215 (6%)

Query: 940  RMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEE 999
            R++ R    + +R+   E  ++LL  E  + L   R+ E R KR +   +  + + EEE 
Sbjct: 527  RLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR-EQRLKREQEERRDQLLKREEER 585

Query: 1000 EEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNF 1059
             ++   + + + +E+ L   E E   +EE R +  ++ +   +R +  LK    +E    
Sbjct: 586  RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE---- 641

Query: 1060 LDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMAD 1119
               +  Q++   Q      R K    +   + RL    E    +  E+E A+ E E+  +
Sbjct: 642  ---RRQQQLRREQQERREQRLKREEEEERLEQRLKREHE---EERREQELAEEEQEQARE 695

Query: 1120 PMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAG 1154
             ++  I   K   +L+ + +A + ++   P+ Q G
Sbjct: 696  RIKSRI--PKWQWQLESEADARQSKVYSRPRKQEG 728



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 56/278 (20%), Positives = 108/278 (38%), Gaps = 51/278 (18%)

Query: 976  KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG-- 1033
            ++EA A++ +  S+   +E +   +E+E  + + +S  +   +       +EEE+ R   
Sbjct: 709  ESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFT 768

Query: 1034 -------KEQR---------KLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGR 1077
                   K +R          L  QR R    E        FL  +  +     Q    R
Sbjct: 769  WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ---RR 825

Query: 1078 GRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQ 1137
             R+K+  F +  + +L  RE A   +++EEE    ED+E     E      ++ QK + Q
Sbjct: 826  EREKELQF-LEEEEQLQRRERA--QQLQEEEDGLQEDQERRRSQE-----QRRDQKWRWQ 877

Query: 1138 KEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNR 1197
             E E +               H   AK A+     K ++   + +++          L R
Sbjct: 878  LEEERKRRR------------HTLYAKPALQEQLRKEQQLLQEEEEE----------LQR 915

Query: 1198 SKLNRRKKMKLQGQFKGLVKAARRGSQVGHKNRRKDRR 1235
             +  +R++ + + Q++   +  +   Q+  + R K RR
Sbjct: 916  EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR 953


>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
          Length = 2211

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 38/108 (35%), Positives = 49/108 (45%), Gaps = 17/108 (15%)

Query: 974  IRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG 1033
            ++K   +AK  R   +    +EE+E EEEE +  +  S EE     E EE+ EEEE   G
Sbjct: 927  LKKERLKAKLQRKKKKRKGSDEEDEGEEEESSSSEESSSEE----EEMEEEEEEEEFGPG 982

Query: 1034 K----EQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGR 1077
                 EQ K    R   WL  G  D  L      V + V A +PGP R
Sbjct: 983  MQEVIEQHKFEAHR---WLARGKEDNEL------VVELVPAGKPGPER 1021



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 15/112 (13%)

Query: 1077 RGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADP-MEDVIIRNK--KHQK 1133
            R +KK  G     +G       ++ +  EEEE  + E+EE   P M++VI ++K   H+ 
Sbjct: 938  RKKKKRKGSDEEDEGEEEESSSSEESSSEEEEMEEEEEEEEFGPGMQEVIEQHKFEAHRW 997

Query: 1134 LKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKG 1185
            L   KE  E  +E+ P   AG  G  R           Y+ +   G+V K G
Sbjct: 998  LARGKEDNELVVELVP---AGKPGPERNT---------YEVQVVTGNVPKAG 1037


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
            [Homo sapiens]
          Length = 517

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 64/282 (22%), Positives = 120/282 (42%), Gaps = 31/282 (10%)

Query: 964  PEEYHRVLVNIRKAEARAKRHRALSQAAV-------EEEEEEEEEEEPAQGKGDSIEEIL 1016
            P   HR L      E   +R++ L+  ++       +++++E+EEE+  +G+  + E  +
Sbjct: 148  PLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRI 207

Query: 1017 ADSEDE-EDNEEEERSRGKEQRKLARQRSRAWLKEGG-------GDEPLNFLDPK----V 1064
             D ED+ E + +   + G+E  ++ + + +A L +GG       G +   F D       
Sbjct: 208  HDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFE 267

Query: 1065 AQRVLATQPGPGRGRKKDHGFKVSA----DGRLIIREEADGNKMEEEEGAKGEDEEMADP 1120
             Q V     G    +++    K  A    +G   + E++D ++  EEE    ED+E  + 
Sbjct: 268  GQEVDYMSDGSSSSQEEPES-KAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEE 326

Query: 1121 MEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVAKKAMPGAEYKAKKAKGD 1180
             +    + KK +K   ++    EE +I  +     S +   +AKK  P  + + K + G 
Sbjct: 327  KKAPTPQEKKRRKDSSEESDSSEESDIDSE---ASSALF--MAKKKTP-PKRERKPSGGS 380

Query: 1181 VKKKGRP-DPYAYIPLNRSKLNRRKKMKLQGQFKGLVKAARR 1221
             +   RP  P A      S L        QG+    + AA+R
Sbjct: 381  SRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKR 422


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
          Length = 1341

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 52/195 (26%), Positives = 81/195 (41%), Gaps = 20/195 (10%)

Query: 975  RKAEARAKRHRALSQAAVEE----EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEER 1030
            RK E R+ R R    A + E     EEEE++E P++      +  L   E+EE+ EEEE 
Sbjct: 222  RKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEE 281

Query: 1031 SRGKEQRKLARQRSR-----AWLKEGGGD----EPLNFLD--PKV-AQRVLATQPGPGRG 1078
               +E+     Q+SR        KE G +    +P   +D  PK  +Q     + G    
Sbjct: 282  DDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFT 341

Query: 1079 RKKDHGFKVSADGRLIIREEADGNKMEEEE----GAKGEDEEMADPMEDVIIRNKKHQKL 1134
            R ++   K     +   +E    + +EEEE     ++G  E+   P    +  ++K   L
Sbjct: 342  RSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASL 401

Query: 1135 KHQKEAEEEELEIPP 1149
                E    E E PP
Sbjct: 402  VALPEQTASEEETPP 416



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 46/160 (28%), Positives = 61/160 (38%), Gaps = 35/160 (21%)

Query: 989  QAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWL 1048
            Q+++E  E E     P   K  SI E   DS+DE+  + E RS         RQ   A L
Sbjct: 188  QSSLERPELELSRHSPR--KSSSISEEKGDSDDEKPRKGERRS------SRVRQARAAKL 239

Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE 1108
             EG          P   +     Q  P R                 +R  AD N   EEE
Sbjct: 240  SEGS--------QPAEEEE---DQETPSRN----------------LRVRADRNLKTEEE 272

Query: 1109 GAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIP 1148
              + E+EE  D  E+     +K ++    KE +EE  EIP
Sbjct: 273  EEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIP 312



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 44/207 (21%), Positives = 87/207 (42%), Gaps = 25/207 (12%)

Query: 957  ELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS----- 1011
            E V  LLP ++     ++ + E    RH     +++ EE+ + ++E+P +G+  S     
Sbjct: 177  EGVASLLPPDFQS---SLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQ 233

Query: 1012 -----IEEILADSEDEEDNEEEERS-RGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVA 1065
                 + E    +E+EED E   R+ R +  R L  +      +E   D+     D +  
Sbjct: 234  ARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQ 293

Query: 1066 QRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE-----GAKGEDEEMADP 1120
            +    ++  P     K+ G ++       + +E    + +E+E     G     +E A  
Sbjct: 294  K----SREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEA-- 347

Query: 1121 MEDVIIRNKKHQKLKHQKEAEEEELEI 1147
             +  + R ++ +++K     EEEE EI
Sbjct: 348  RKSHLARQQQEKEMKTTSPLEEEEREI 374



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 6/78 (7%)

Query: 974  IRKAEARAKRHRALSQAAVEEEEEE--EEEEEPAQGKGDSIEEIL----ADSEDEEDNEE 1027
            ++K   RA+R +   +   E+EEEE  E E+E  + +   +E       +   D E   E
Sbjct: 1235 VQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERE 1294

Query: 1028 EERSRGKEQRKLARQRSR 1045
             ER RG   R   R R R
Sbjct: 1295 RERDRGDRDRDRERDRER 1312



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 10/83 (12%)

Query: 975  RKAEARAKRHRALSQAAVEE---EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031
            R+ EA  +R+R L +    E   E + E E E  + +GD       D + E D E     
Sbjct: 1263 REKEAERERNRQLEREKRREHSRERDRERERERERDRGD------RDRDRERDRERGRER 1316

Query: 1032 RGKEQRKLARQRSRAW-LKEGGG 1053
              ++ ++ +R RSR+  +++ GG
Sbjct: 1317 DRRDTKRHSRSRSRSTPVRDRGG 1339



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 29/155 (18%), Positives = 67/155 (43%), Gaps = 24/155 (15%)

Query: 976  KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEI----------LADSE-DEED 1024
            ++  R ++ RA S+    E++E+ +EE PA+   D   +           L DS+  +++
Sbjct: 1179 RSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKE 1238

Query: 1025 NEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHG 1084
             E  ER++ +E+R+  ++      +E   +   N    +  +R  + +    R R+++  
Sbjct: 1239 AERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERE-- 1296

Query: 1085 FKVSADGRLIIREEADGNKMEEEEGAKGEDEEMAD 1119
                       R+  D ++  E +  +G + +  D
Sbjct: 1297 -----------RDRGDRDRDRERDRERGRERDRRD 1320


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 1/66 (1%)

Query: 978  EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK-EQ 1036
            E  A++   + +  VEEEEEE EEEE  + K +  EE   + E EED EEEE+   K E+
Sbjct: 109  ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168

Query: 1037 RKLARQ 1042
             K+  +
Sbjct: 169  EKVEEE 174



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 1/70 (1%)

Query: 975  RKAEARAKRHRALSQAAVEEEE-EEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRG 1033
            R A   A+   A     VEEEE EEEEEE   + K +  EE   + E EE+ EE+E    
Sbjct: 101  RTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEE 160

Query: 1034 KEQRKLARQR 1043
            KE +K+  ++
Sbjct: 161  KEGKKMEEEK 170



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 972  VNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031
            +++ +  A      +  Q    EEEE EEEEE        +EE   + E EED EEEE+ 
Sbjct: 97   LSVARTAALVAEECSAQQGLPVEEEEVEEEEE-------EVEEEEKEEEKEEDEEEEEKE 149

Query: 1032 RGKEQRKLARQRSRAWLKEGGGDEPLN 1058
              KE+ +   ++    ++E   +E ++
Sbjct: 150  EEKEEDEEEEEKEGKKMEEEKVEEEID 176



 Score = 31.2 bits (69), Expect = 6.4
 Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 4/62 (6%)

Query: 965  EEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEED 1024
            EE       + + E   ++     +   EEE+EE+EEEE  +GK    E++    E+E D
Sbjct: 121  EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV----EEEID 176

Query: 1025 NE 1026
             E
Sbjct: 177  TE 178


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
          Length = 1293

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 25/189 (13%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEE--DNEEEERSR 1032
            R+AE RAKR         EEEE + +EE   Q      EEIL   ++EE    EEEE +R
Sbjct: 736  REAEMRAKR---------EEEERKRQEELRRQQ-----EEILRRQQEEERKRREEEELAR 781

Query: 1033 GKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092
             K++  L RQR +        +E       +  +R+          R+++   +   +  
Sbjct: 782  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEEL 833

Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE-EEELEIPPQY 1151
            L  +EE       EEE A+   EE    ME+   R +  ++ + +KE E + + E+  Q 
Sbjct: 834  LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 893

Query: 1152 QAGGSGIHR 1160
            Q     + R
Sbjct: 894  QQQQEALRR 902



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 18/172 (10%)

Query: 994  EEEEEEEEEEPAQGKGDSIE-EILADSEDEEDNEEEERSRGKEQ---RKLARQRSRAWLK 1049
            E+ ++ E+ + A+ + +  E E+ A  E+EE   +EE  R +E+   R+   +R R   +
Sbjct: 718  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777

Query: 1050 EGGGDEPLNFLDPKVAQRV-LATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKME--- 1105
            E    +    L  +  Q + L  Q      ++++   +   + R   REE +  K E   
Sbjct: 778  ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---REEEERRKQEELL 834

Query: 1106 ---EEEGAK--GEDEEMADPMEDVIIR-NKKHQKLKH-QKEAEEEELEIPPQ 1150
               EEE AK   E+EE    +E+  +R  ++  +L+H ++E + +ELE+  Q
Sbjct: 835  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 886


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
          Length = 1320

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 25/189 (13%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEE--DNEEEERSR 1032
            R+AE RAKR         EEEE + +EE   Q      EEIL   ++EE    EEEE +R
Sbjct: 763  REAEMRAKR---------EEEERKRQEELRRQQ-----EEILRRQQEEERKRREEEELAR 808

Query: 1033 GKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092
             K++  L RQR +        +E       +  +R+          R+++   +   +  
Sbjct: 809  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEEL 860

Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE-EEELEIPPQY 1151
            L  +EE       EEE A+   EE    ME+   R +  ++ + +KE E + + E+  Q 
Sbjct: 861  LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 920

Query: 1152 QAGGSGIHR 1160
            Q     + R
Sbjct: 921  QQQQEALRR 929



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 18/172 (10%)

Query: 994  EEEEEEEEEEPAQGKGDSIE-EILADSEDEEDNEEEERSRGKEQ---RKLARQRSRAWLK 1049
            E+ ++ E+ + A+ + +  E E+ A  E+EE   +EE  R +E+   R+   +R R   +
Sbjct: 745  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804

Query: 1050 EGGGDEPLNFLDPKVAQRV-LATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKME--- 1105
            E    +    L  +  Q + L  Q      ++++   +   + R   REE +  K E   
Sbjct: 805  ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---REEEERRKQEELL 861

Query: 1106 ---EEEGAK--GEDEEMADPMEDVIIR-NKKHQKLKH-QKEAEEEELEIPPQ 1150
               EEE AK   E+EE    +E+  +R  ++  +L+H ++E + +ELE+  Q
Sbjct: 862  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 25/189 (13%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEE--DNEEEERSR 1032
            R+AE RAKR         EEEE + +EE   Q      EEIL   ++EE    EEEE +R
Sbjct: 742  REAEMRAKR---------EEEERKRQEELRRQQ-----EEILRRQQEEERKRREEEELAR 787

Query: 1033 GKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092
             K++  L RQR +        +E       +  +R+          R+++   +   +  
Sbjct: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEEL 839

Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE-EEELEIPPQY 1151
            L  +EE       EEE A+   EE    ME+   R +  ++ + +KE E + + E+  Q 
Sbjct: 840  LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899

Query: 1152 QAGGSGIHR 1160
            Q     + R
Sbjct: 900  QQQQEALRR 908



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 18/172 (10%)

Query: 994  EEEEEEEEEEPAQGKGDSIE-EILADSEDEEDNEEEERSRGKEQ---RKLARQRSRAWLK 1049
            E+ ++ E+ + A+ + +  E E+ A  E+EE   +EE  R +E+   R+   +R R   +
Sbjct: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783

Query: 1050 EGGGDEPLNFLDPKVAQRV-LATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKME--- 1105
            E    +    L  +  Q + L  Q      ++++   +   + R   REE +  K E   
Sbjct: 784  ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---REEEERRKQEELL 840

Query: 1106 ---EEEGAK--GEDEEMADPMEDVIIR-NKKHQKLKH-QKEAEEEELEIPPQ 1150
               EEE AK   E+EE    +E+  +R  ++  +L+H ++E + +ELE+  Q
Sbjct: 841  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
          Length = 1299

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 25/189 (13%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEE--DNEEEERSR 1032
            R+AE RAKR         EEEE + +EE   Q      EEIL   ++EE    EEEE +R
Sbjct: 742  REAEMRAKR---------EEEERKRQEELRRQQ-----EEILRRQQEEERKRREEEELAR 787

Query: 1033 GKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092
             K++  L RQR +        +E       +  +R+          R+++   +   +  
Sbjct: 788  RKQEEALRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEEL 839

Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAE-EEELEIPPQY 1151
            L  +EE       EEE A+   EE    ME+   R +  ++ + +KE E + + E+  Q 
Sbjct: 840  LRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR 899

Query: 1152 QAGGSGIHR 1160
            Q     + R
Sbjct: 900  QQQQEALRR 908



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 18/172 (10%)

Query: 994  EEEEEEEEEEPAQGKGDSIE-EILADSEDEEDNEEEERSRGKEQ---RKLARQRSRAWLK 1049
            E+ ++ E+ + A+ + +  E E+ A  E+EE   +EE  R +E+   R+   +R R   +
Sbjct: 724  EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783

Query: 1050 EGGGDEPLNFLDPKVAQRV-LATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKME--- 1105
            E    +    L  +  Q + L  Q      ++++   +   + R   REE +  K E   
Sbjct: 784  ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR---REEEERRKQEELL 840

Query: 1106 ---EEEGAK--GEDEEMADPMEDVIIR-NKKHQKLKH-QKEAEEEELEIPPQ 1150
               EEE AK   E+EE    +E+  +R  ++  +L+H ++E + +ELE+  Q
Sbjct: 841  RKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 11/116 (9%)

Query: 976  KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035
            +AE + ++ R +   A EE E EEE E   + + +   E  +D E EED+EEE     + 
Sbjct: 80   EAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQES 139

Query: 1036 QRKLARQRSRAWLKEGGGDEPLNFLDPKV---AQRVLATQPGPGRGRKKDHGFKVS 1088
            + +   Q       EG  +    F DP++   A+RV        + +  DHG  +S
Sbjct: 140  EAEEDNQEEGESEAEGETEAESEF-DPEIEMEAERV-------AKRKCPDHGLDLS 187



 Score = 35.0 bits (79), Expect = 0.44
 Identities = 18/55 (32%), Positives = 29/55 (52%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEE 1029
            R+ E+ A       + +  EEE E EEE   +   +S E+   + EDE+++E EE
Sbjct: 89   REIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEE 143



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 34/146 (23%), Positives = 57/146 (39%), Gaps = 9/146 (6%)

Query: 1005 AQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKV 1064
            A G G + EE+  D   +E   +E  + G E+  + R+    + +         FL   +
Sbjct: 2    ASGVGAAFEELPHDGTCDECEPDE--APGAEE--VCRECGFCYCRRHAEAHRQKFLSHHL 57

Query: 1065 AQRVLATQ----PGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADP 1120
            A+ V  +Q    P  G G  K+   +V  +    I  EA      EEE    E+ E  + 
Sbjct: 58   AEYVHGSQAWTPPADGEGAGKEEA-EVKVEQEREIESEAGEESESEEESESEEESETEEE 116

Query: 1121 MEDVIIRNKKHQKLKHQKEAEEEELE 1146
             ED      +    +  ++ +E E E
Sbjct: 117  SEDESDEESEEDSEEEMEDEQESEAE 142


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 39/165 (23%), Positives = 77/165 (46%), Gaps = 9/165 (5%)

Query: 982  KRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEE--RSRGKEQRKL 1039
            K+    ++   EEE+++E+EE+  + KG++ +E   D + EED +E++    +G++ ++ 
Sbjct: 115  KKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED-KDEKGEEDGKEDKNGNEKGEDAKEK 173

Query: 1040 ARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEA 1099
               +     K  G D      D K  +    T  G      K+ G K       +  +E 
Sbjct: 174  EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK 233

Query: 1100 DGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144
            +    +E+EG  G +EE     ED+    K+ ++ K + E +E++
Sbjct: 234  EREDGKEDEG--GNEEEAGKEKEDL----KEEEEGKEEDEIKEDD 272



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 49/205 (23%), Positives = 91/205 (44%), Gaps = 31/205 (15%)

Query: 962  LLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSED 1021
            ++ E+Y+    N +  EA+     A  +  VE +EE  E+    +  G+  E + A+ ++
Sbjct: 71   VVEEDYNE---NAKNGEAKITEAPASEKEIVEVKEENIEDA--TEKGGEKKEAVAAEVKN 125

Query: 1022 EEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLN----FLDPKVAQRVLATQPGPGR 1077
            EE++++E+     E++  A +  +    E  G E  N      D K  +     + G G 
Sbjct: 126  EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGN 185

Query: 1078 G---------RKKDHGFKVSADGRLIIREEADG-NKMEEEEG----AKGEDEEMADPMED 1123
            G          K++   K + DG    +E  DG  K +++EG     K +++E  D  ED
Sbjct: 186  GEDGKEKGEDEKEEEDRKETGDG----KENEDGKEKGDKKEGKDVKVKEDEKEREDGKED 241

Query: 1124 ----VIIRNKKHQKLKHQKEAEEEE 1144
                     K+ + LK ++E +EE+
Sbjct: 242  EGGNEEEAGKEKEDLKEEEEGKEED 266


>gi|42476169 Paf1, RNA polymerase II associated factor, homolog [Homo
            sapiens]
          Length = 531

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 19/162 (11%)

Query: 972  VNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031
            +N ++ EA+  R   L     EEEEEEE E E  +  G   E+    S ++E +E+E   
Sbjct: 356  MNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH-- 413

Query: 1032 RGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADG 1091
             G E  +    R  A  K G G++  +  + + A             R K+  F   AD 
Sbjct: 414  SGSESEREEGDRDEASDKSGSGEDESSEDEARAA-------------RDKEEIFGSDADS 460

Query: 1092 RLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQK 1133
                 ++AD +  +  +   G D +          R++ H +
Sbjct: 461  ----EDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSR 498



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 36/185 (19%), Positives = 78/185 (42%), Gaps = 12/185 (6%)

Query: 937  RHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAK---RHRALSQAAVE 993
            R +   ++N  +K   +  F + +      Y+ +   +R ++ RAK   +    +   V+
Sbjct: 293  REYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVK 352

Query: 994  EEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGG 1053
              +  E+E E  + +   +E    + E+EE+ E EE+  G    +  +++  +  KEG  
Sbjct: 353  HRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEE--QEKGSSSEKEGSE 410

Query: 1054 DEPLNFLDPKVA--QRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK 1111
            DE       +    +   + + G G     +   + + D     +EE  G+  + E+ A 
Sbjct: 411  DEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARD-----KEEIFGSDADSEDDAD 465

Query: 1112 GEDEE 1116
             +DE+
Sbjct: 466  SDDED 470



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 13/82 (15%)

Query: 983  RHRALSQAAVEEEEEEEEEEEPAQGK-----GDSIEEILADSEDEE--------DNEEEE 1029
            R  A  ++   E+E  E+E   A+ K      D+  E  ADS+DE+        DN+ + 
Sbjct: 425  RDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDS 484

Query: 1030 RSRGKEQRKLARQRSRAWLKEG 1051
             S G  QR  +  RS +    G
Sbjct: 485  GSNGGGQRSRSHSRSASPFPSG 506


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 49/195 (25%), Positives = 89/195 (45%), Gaps = 41/195 (21%)

Query: 936  RRHFRMKLRNLFTKFIRKF-GFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAA--V 992
            RR    KLR     +  +   +E+ +R    EY +      +AE   +R R +++ A  +
Sbjct: 443  RRKLERKLREKEAAYQERLKNWEIRERKKTREYEK------EAEREEERRREMAKEAKRL 496

Query: 993  EE--EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKE 1050
            +E  E+ +++ ++P   +G ++++ L D E E + +E +R R KE+ +  RQR    L E
Sbjct: 497  KEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQR---LLAE 553

Query: 1051 G--GGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEE 1108
            G    D  L  ++ +  +R    QP                     I++E +  + EEE+
Sbjct: 554  GHPDPDAELQRMEQEAERR---RQPQ--------------------IKQEPESEEEEEEK 590

Query: 1109 GAKGEDEEMADPMED 1123
              K E  E  +PME+
Sbjct: 591  QEKEEKRE--EPMEE 603



 Score = 38.5 bits (88), Expect = 0.040
 Identities = 44/194 (22%), Positives = 77/194 (39%), Gaps = 13/194 (6%)

Query: 965  EEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEED 1024
            EE  R L++   ++ R    +   +   +E+E +E E+E  + + +   E      + E 
Sbjct: 270  EEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERER 329

Query: 1025 NEEEERSRGKE-QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDH 1083
              E ER + KE +R+  R R R   KE   D        +  +R         R R+K  
Sbjct: 330  EREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSR 389

Query: 1084 GFKVSADGRLIIRE-----------EADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQ 1132
              +   + R   RE           E +  +  E E  K +  +  +  ED   R K  +
Sbjct: 390  DRERERE-REREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448

Query: 1133 KLKHQKEAEEEELE 1146
            KL+ ++ A +E L+
Sbjct: 449  KLREKEAAYQERLK 462



 Score = 38.5 bits (88), Expect = 0.040
 Identities = 64/298 (21%), Positives = 123/298 (41%), Gaps = 32/298 (10%)

Query: 942  KLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEA-RAKRHRALSQAAVEEEEEEEE 1000
            K R+   K   + G +  +R   E+  R     R+ E  R +R R   +    E+E+E E
Sbjct: 283  KFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERE 342

Query: 1001 EEEPAQGKGDSIEEILADSEDEEDNEEE---------ERSRGKEQ---RKLARQRSRAWL 1048
             E       D  +E   D + E D + +         +RSR +E+   R+  R+R R   
Sbjct: 343  RERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERE 402

Query: 1049 KEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHG---FKVSADGRLIIREEADGNKM- 1104
            +E   +        +  +R    +    R R++D      +   + +L  +E A   ++ 
Sbjct: 403  REREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLK 462

Query: 1105 --EEEEGAKGEDEEMADPMEDVIIRN--KKHQKLKHQKEAEEEELEIPPQYQAGGSGIHR 1160
              E  E  K  + E     E+   R   K+ ++LK   E  +++ + P  Y+  GS + +
Sbjct: 463  NWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR--GSALQK 520

Query: 1161 PV--AKKAMPGAEYKAKKAKGDVKK-------KGRPDPYAYIPLNRSKLNRRKKMKLQ 1209
             +   +K M   E   K+ K ++++       +G PDP A +     +  RR++ +++
Sbjct: 521  RLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIK 578



 Score = 37.4 bits (85), Expect = 0.089
 Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 34/204 (16%)

Query: 976  KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035
            K+  R +      +   E E E E E E  + +    E       D E++EE+   R K 
Sbjct: 387  KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKL 446

Query: 1036 QRKL-----------------ARQRSRAWLKEGGGDEPLNFLDPKVAQRVL--------- 1069
            +RKL                  R+++R + KE   +E       K A+R+          
Sbjct: 447  ERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDD 506

Query: 1070 ATQPGPGRG-----RKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMAD--PME 1122
               P   RG     R +D   ++ AD R   RE+ +  ++ +   A+G  +  A+   ME
Sbjct: 507  RDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRME 566

Query: 1123 DVIIRNKKHQKLKHQKEAEEEELE 1146
                R ++ Q +K + E+EEEE E
Sbjct: 567  QEAERRRQPQ-IKQEPESEEEEEE 589



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 957  ELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEIL 1016
            E+ +RLL E +      +++ E  A+R R        E EEEEEE+   Q K +  EE +
Sbjct: 545  EIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEK---QEKEEKREEPM 601

Query: 1017 ADSEDEE 1023
             + E+ E
Sbjct: 602  EEEEEPE 608



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 36/173 (20%), Positives = 63/173 (36%), Gaps = 19/173 (10%)

Query: 991  AVEEEEEE------------------EEEEEPAQGKGDSIEEILADSEDEEDNEEEERSR 1032
            A+E EE++                  EEE+   + +   IE+   + E E + E E R R
Sbjct: 266  AIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRER 325

Query: 1033 GKE-QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADG 1091
             +E +R+  R++ +   +E   D   +    +   R         R R  D     S   
Sbjct: 326  EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385

Query: 1092 RLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144
                  E +  +  E E  +  + E     E    R ++ +K K +   E+EE
Sbjct: 386  EKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE 438


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
            containing B [Homo sapiens]
          Length = 546

 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 52/262 (19%), Positives = 102/262 (38%), Gaps = 34/262 (12%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034
            R++ +R+        ++ + E E E+E +  + +    E+    S   +   E  RSR +
Sbjct: 274  RRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSR 333

Query: 1035 EQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGF-KVSADGRL 1093
            E     R RSR+  ++  GD            R    +    RGR++D  + K   + R 
Sbjct: 334  E-----RHRSRSRSRDRKGDR---------RDRDREREKENERGRRRDRDYDKERGNERE 379

Query: 1094 IIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQA 1153
              RE +     E+    + E+++  +  +D   R+ K    K +K +     E   + ++
Sbjct: 380  KERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRS 439

Query: 1154 GGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPDPYAYIPLNRSKLNRRKKMKLQGQFK 1213
                  R   K++   ++ K+ K K + K+K                N+R +   QG+  
Sbjct: 440  RS----RNAGKRSRSRSKEKSSKHKNESKEKS---------------NKRSRSGSQGRTD 480

Query: 1214 GLVKAARRGSQVGHKNRRKDRR 1235
             + K+ +R      +  RK  R
Sbjct: 481  SVEKSKKREHSPSKEKSRKRSR 502



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 6/80 (7%)

Query: 966  EYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDN 1025
            +Y +   N R+ E    R R+  Q +  E EE++ +E+    +         D  D +  
Sbjct: 369  DYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRD------DKRDSKKE 422

Query: 1026 EEEERSRGKEQRKLARQRSR 1045
            ++  RSR +E++  +R RSR
Sbjct: 423  KKHSRSRSRERKHRSRSRSR 442



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 34/176 (19%), Positives = 65/176 (36%), Gaps = 7/176 (3%)

Query: 975  RKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGK 1034
            R  E    R R+  +     + + E E+E  +G+    +       + E   E  R R K
Sbjct: 331  RSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSK 390

Query: 1035 EQRKLARQRSRAWLKEGGGDEPL--NFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGR 1092
            EQR       +   KE   D     +  D K  ++   ++    + R +          R
Sbjct: 391  EQRSRGEVEEKKH-KEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR 449

Query: 1093 LIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQ----KLKHQKEAEEEE 1144
               +E++  +K E +E +       +    D + ++KK +    K K +K +  +E
Sbjct: 450  SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKE 505


>gi|5453567 craniofacial development protein 1 [Homo sapiens]
          Length = 299

 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 57/227 (25%), Positives = 99/227 (43%), Gaps = 45/227 (19%)

Query: 975  RKAE---ARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031
            RKA+   AR +R   LS       EEEEEE+  ++ +G S       SE+E+D  E+E+ 
Sbjct: 53   RKAQSIPARKRRQGGLSL------EEEEEEDANSESEGSS-------SEEEDDAAEQEKG 99

Query: 1032 RGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADG 1091
             G E  +  ++    W         LN + PK       ++  P    KK    + ++  
Sbjct: 100  IGSEDAR-KKKEDELWASF------LNDVGPK-------SKVPPSTQVKKGEETEETSSS 145

Query: 1092 RLIIREEADGNKMEEEEGAK--------GEDEEMADPMEDVIIRNKKHQKLKHQKEAEEE 1143
            +L+++ E +  K +E E  K        GE+  +    ++V   +K+ +    Q E E+ 
Sbjct: 146  KLLVKAE-ELEKPKETEKVKITKVFDFAGEEVRVT---KEVDATSKEAKSFFKQNEKEKP 201

Query: 1144 ELEIPPQYQA--GGSGIHRPVAKKAMPGAEYKAKKAKGDVKKKGRPD 1188
            +  +P    +   GSG+ R     ++ G +  AKK K    +K + D
Sbjct: 202  QANVPSALPSLPAGSGLKRSSGMSSLLG-KIGAKKQKMSTLEKSKLD 247


>gi|28274705 family with sequence similarity 9, member A [Homo
            sapiens]
          Length = 332

 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 40/132 (30%), Positives = 57/132 (43%), Gaps = 24/132 (18%)

Query: 937  RHFRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAV---- 992
            RH R KL N+  ++I        ++   +E          AEA A    A + A V    
Sbjct: 169  RHTR-KLLNVLKEYI-------AEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVE 220

Query: 993  ---------EEEEEEEEEEEPAQGKGDSIEEILA---DSEDEEDNEEEERSRGKEQRKLA 1040
                     EEE+EEEEEE   +G G+  EE        E EE+ EEEE    +EQ K  
Sbjct: 221  DEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAF 280

Query: 1041 RQRSRAWLKEGG 1052
            +++ + W +  G
Sbjct: 281  QEKQKRWQQPTG 292



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 46/236 (19%), Positives = 95/236 (40%), Gaps = 57/236 (24%)

Query: 909  VTVMDVAHLAKHVQLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKRLLPEEYH 968
            +  M + H+A  ++  + A  ++    +  +R K +N   + ++K   +  KR     + 
Sbjct: 115  IHTMKLEHIAADIKKGLAAKREMIKIDKAAYR-KTKNTIERALKKKQLKRQKR--DYRHT 171

Query: 969  RVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIE---------EILADS 1019
            R L+N+ K              A +++++E EE E A    ++           E++   
Sbjct: 172  RKLLNVLK-----------EYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVE 220

Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGR 1079
            ++EE+ +EEE  + +E+ +          +EGGG+E                + G G G 
Sbjct: 221  DEEEEEKEEEEEKEEEEEE--------GEEEGGGEE---------------GEEGGGGG- 256

Query: 1080 KKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLK 1135
                      +G     EE +  + EEEE  K   E+     +   +R+ + +++K
Sbjct: 257  ----------EGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMK 302


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 828

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 39/189 (20%), Positives = 88/189 (46%), Gaps = 15/189 (7%)

Query: 960  KRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADS 1019
            ++ + EE   +     K + + ++ R   +   E+EE+ +E+EE    K    EE + + 
Sbjct: 566  EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE----KMWEQEEKMWEQ 621

Query: 1020 EDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGR 1079
            E+E+  +E+E    +++ K+  Q  + W +E    E +   + K+ ++    Q    + R
Sbjct: 622  EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE----EKMREQEEKMREQEEKMQGQEEKMR 677

Query: 1080 KKDHGFKVSADGRLIIREEADGNKME---EEEGAKGEDEEMADPMEDVIIRNKKHQKLKH 1136
            +++   +   +      E+  G + +   +EE   G++E+M    E      +K ++++ 
Sbjct: 678  EQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE----MREKEERIRD 733

Query: 1137 QKEAEEEEL 1145
            QKE  +E L
Sbjct: 734  QKEKMQERL 742



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 43/177 (24%), Positives = 85/177 (48%), Gaps = 15/177 (8%)

Query: 978  EARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQR 1037
            E   K  R   +   +E+E  E+E+E  + K    +E     ++E+  E+EE+ R +E+ 
Sbjct: 273  EQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE- 331

Query: 1038 KLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIRE 1097
            K+ RQ  R W +E    + +   + K+  +         R R+K+   ++    ++  +E
Sbjct: 332  KMWRQEERLWEQE----KQMREQEQKMRDQEERMWEQDERLREKEE--RMREQEKMWEQE 385

Query: 1098 EADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQK----LKHQKEAEEEELEIPPQ 1150
            E    KM+EEE  +  +++M +  E +  + +K QK    +  Q+E E ++  +P Q
Sbjct: 386  E----KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 438



 Score = 38.9 bits (89), Expect = 0.031
 Identities = 35/178 (19%), Positives = 84/178 (47%), Gaps = 18/178 (10%)

Query: 974  IRKAEARAKRHRAL--SQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERS 1031
            +R+ E R +    +   +  ++EEE   E E+  + + +++ E     + +E+N  E+  
Sbjct: 368  LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 427

Query: 1032 RGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADG 1091
            +  +Q++L  Q+ + W +E   ++     + +  +++   +   G+ +K     K     
Sbjct: 428  KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE--EKIRDQEEMWGQEKKMWRQEK----- 480

Query: 1092 RLIIREEADGNKMEEEEGAKGEDEEMADPME-----DVIIRNKKHQKLKHQKEAEEEE 1144
               +RE+ D    E+EE  + ++++M D  E     D  +R K+ +  + +K  ++EE
Sbjct: 481  ---MREQED-QMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE 534



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 14/165 (8%)

Query: 980  RAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKL 1039
            R K  R   Q  + ++EE+  EE+  Q +    E+   D E++   EE  R R K+ R+ 
Sbjct: 517  REKEERMREQKKMWQQEEKMREEKKTQEQ----EKKTWDQEEKMREEERMREREKKMREE 572

Query: 1040 ARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEA 1099
                     K    +E +   + K+ ++    Q    +  +++            + E+ 
Sbjct: 573  EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK----------MWEQE 622

Query: 1100 DGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144
            + +KM+E+E    E EE     E+ +   ++  + + +K  E+EE
Sbjct: 623  EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 46/206 (22%), Positives = 88/206 (42%), Gaps = 28/206 (13%)

Query: 956  FELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEI 1015
            +E  +++  EE  R      + E    R +       EE   E+EE+E  Q +    +E 
Sbjct: 382  WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 441

Query: 1016 LADSEDEEDNEE-----EERSRGKE-----------QRKLARQRSRAWLKEGGGDEPLNF 1059
            L + E  ++ EE     EE+ R +E           Q K+  Q  + W +E    E +  
Sbjct: 442  LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE----EKMRD 497

Query: 1060 LDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGEDEEMAD 1119
             + K+  +         R R+K+   ++    ++  +EE    KM EE+  + ++++  D
Sbjct: 498  QEQKMWDQEERMWEQDERLREKEE--RMREQKKMWQQEE----KMREEKKTQEQEKKTWD 551

Query: 1120 PMEDVIIRNKKHQKLKHQKEAEEEEL 1145
              E   +R ++  + + +K  EEEE+
Sbjct: 552  QEEK--MREEERMREREKKMREEEEM 575



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 45/201 (22%), Positives = 91/201 (45%), Gaps = 30/201 (14%)

Query: 974  IRKAEARAKRHRALSQAAVEEEEEEE---EEEEPAQGKGDSI---EEILADSE------- 1020
            +R+ E   +  + L +   + +E+EE   E+EE  + + + +   EE L + E       
Sbjct: 292  LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351

Query: 1021 ----DEEDN--EEEERSRGKEQRKLARQRSRAWLKEGG--GDEPLNFLDPKVAQRVLATQ 1072
                D+E+   E++ER R KE+R   R++ + W +E     +E +   + K+ +     +
Sbjct: 352  QKMRDQEERMWEQDERLREKEERM--REQEKMWEQEEKMQEEERIREREKKMREEEETMR 409

Query: 1073 PGPGRGRKKDHGF-----KVSADGRLIIREEA--DGNKMEEEEGAKGEDEEMADPMEDVI 1125
                + +K++        K     RL  ++E   +  KM+E+E    E EE     E++ 
Sbjct: 410  EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW 469

Query: 1126 IRNKKHQKLKHQKEAEEEELE 1146
             + KK  + +  +E E++  E
Sbjct: 470  GQEKKMWRQEKMREQEDQMWE 490



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 44/177 (24%), Positives = 82/177 (46%), Gaps = 29/177 (16%)

Query: 993  EEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGG 1052
            +EE+  ++EE   Q K    +E + + ED+   E+EE+ R +EQ K+  Q  R W +   
Sbjct: 458  QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW-EQEEKMRDQEQ-KMWDQEERMWEQ--- 512

Query: 1053 GDEPLNFLDPKVA-QRVLATQPGPGRGRKK---------DHGFKVSADGRLIIRE----- 1097
             DE L   + ++  Q+ +  Q    R  KK         D   K+  + R+  RE     
Sbjct: 513  -DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571

Query: 1098 ------EADGNKMEEEEGAKGEDEEMADPMEDVIIRNKK--HQKLKHQKEAEEEELE 1146
                  E +    E+EE  + ++E+M +  E +  + +K   Q+ K  ++ EE++++
Sbjct: 572  EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 12/170 (7%)

Query: 980  RAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKL 1039
            R ++ R       E+EE+  ++E+    + + + E     +DE   E+EER R  EQ+K+
Sbjct: 477  RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE-----QDERLREKEERMR--EQKKM 529

Query: 1040 ARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEA 1099
             +Q  +   ++   ++     D +   R         +  +++       + ++  +EE 
Sbjct: 530  WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589

Query: 1100 ---DGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEA--EEEE 1144
                  KM E+E    E EE     E+ +   ++  K++ Q+E   E+EE
Sbjct: 590  MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 33/190 (17%)

Query: 989  QAAVEEEEEEEEE-----EEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQR 1043
            QA  EE EE EEE     E PA    DS      ++++ E  EEEE+ R  E+++ + + 
Sbjct: 1230 QAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEE 1289

Query: 1044 SRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNK 1103
             +        +EP    +P+  +   A        +  DH      DG L    E+   K
Sbjct: 1290 QQEL------EEP----EPEEEEDAAAE-----TAQNDDHDADDEDDGHL----ESTKKK 1330

Query: 1104 MEEEEGAKGEDEEMADPMEDVIIRN--KKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRP 1161
              EE+  + + +E     E  +  N  K  +K+K ++E E +  E  P +          
Sbjct: 1331 ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTS------- 1383

Query: 1162 VAKKAMPGAE 1171
            V  + M G+E
Sbjct: 1384 VVSEQMAGSE 1393



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 26/176 (14%)

Query: 976  KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035
            + E   ++ R   +    EEE++E EE   + + D+  E   + + + D+E++      +
Sbjct: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328

Query: 1036 QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLII 1095
            +++L  Q +R  +KE  G +  +FLD  +              +K     K   +  L  
Sbjct: 1329 KKELEEQPTREDVKEEPGVQE-SFLDANM--------------QKSREKIKDKEETELDS 1373

Query: 1096 REEADGNK----MEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEI 1147
             EE   +      E+  G++ + EE +   E++I       +LK ++E    EL++
Sbjct: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI-------ELKEEEEIPHSELDL 1422



 Score = 37.4 bits (85), Expect = 0.089
 Identities = 40/199 (20%), Positives = 85/199 (42%), Gaps = 27/199 (13%)

Query: 952  RKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS 1011
            RK GF+L + ++P      ++    +  +A R   + ++   EE  E +E+ P   +   
Sbjct: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES---EETVEPKEDMPLPEERKE 1225

Query: 1012 IEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLAT 1071
             EE+ A++E+ E+ EEE+ +        + +   A   +          +P+V +     
Sbjct: 1226 EEEMQAEAEEAEEGEEEDAA--------SSEVPAASPADSSNSPETETKEPEVEEEEEKP 1277

Query: 1072 QPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGE----DEEMADPMEDVIIR 1127
            +    + + ++             ++E +  + EEEE A  E    D+  AD  +D  + 
Sbjct: 1278 RVSEEQRQSEEE------------QQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE 1325

Query: 1128 NKKHQKLKHQKEAEEEELE 1146
            + K ++L+ Q   E+ + E
Sbjct: 1326 STKKKELEEQPTREDVKEE 1344



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 9/125 (7%)

Query: 922  QLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKR--LLPEEYHRVLVNIRKAEA 979
            Q+ ++ + KL+    +     L +L     R   F +++R  L+ +   ++ +N+R  + 
Sbjct: 710  QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDV 769

Query: 980  RAKRHR----ALSQAAVEEEEEEEEEE---EPAQGKGDSIEEILADSEDEEDNEEEERSR 1032
              +  R     +S + V EEEEEE EE   E  Q +   +E  +  S   E+ E++  S 
Sbjct: 770  DPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSV 829

Query: 1033 GKEQR 1037
              E++
Sbjct: 830  ESEKK 834



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%)

Query: 992  VEEEEEEEEEEE--PAQ-----GKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRS 1044
            ++EEEEEE+E E  P +        D +    +     +D EE+E S   +   + +  S
Sbjct: 1067 IDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVS 1126

Query: 1045 RAWLKEGGGDEPLNFLDPKVAQRVLATQPGP-GRGRKKDH---------GFKVSAD---- 1090
                +    D   + L+P  +  +   +  P G+ RK  H         GFK+S +    
Sbjct: 1127 LLRKR----DVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPV 1182

Query: 1091 -GRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144
              +  + E          +    E EE  +P ED+ +  ++ ++ + Q EAEE E
Sbjct: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE 1237


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 33/190 (17%)

Query: 989  QAAVEEEEEEEEE-----EEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQR 1043
            QA  EE EE EEE     E PA    DS      ++++ E  EEEE+ R  E+++ + + 
Sbjct: 1230 QAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEE 1289

Query: 1044 SRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNK 1103
             +        +EP    +P+  +   A        +  DH      DG L    E+   K
Sbjct: 1290 QQEL------EEP----EPEEEEDAAAE-----TAQNDDHDADDEDDGHL----ESTKKK 1330

Query: 1104 MEEEEGAKGEDEEMADPMEDVIIRN--KKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRP 1161
              EE+  + + +E     E  +  N  K  +K+K ++E E +  E  P +          
Sbjct: 1331 ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTS------- 1383

Query: 1162 VAKKAMPGAE 1171
            V  + M G+E
Sbjct: 1384 VVSEQMAGSE 1393



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 26/176 (14%)

Query: 976  KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035
            + E   ++ R   +    EEE++E EE   + + D+  E   + + + D+E++      +
Sbjct: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328

Query: 1036 QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLII 1095
            +++L  Q +R  +KE  G +  +FLD  +              +K     K   +  L  
Sbjct: 1329 KKELEEQPTREDVKEEPGVQE-SFLDANM--------------QKSREKIKDKEETELDS 1373

Query: 1096 REEADGNK----MEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEI 1147
             EE   +      E+  G++ + EE +   E++I       +LK ++E    EL++
Sbjct: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI-------ELKEEEEIPHSELDL 1422



 Score = 37.4 bits (85), Expect = 0.089
 Identities = 40/199 (20%), Positives = 85/199 (42%), Gaps = 27/199 (13%)

Query: 952  RKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS 1011
            RK GF+L + ++P      ++    +  +A R   + ++   EE  E +E+ P   +   
Sbjct: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES---EETVEPKEDMPLPEERKE 1225

Query: 1012 IEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLAT 1071
             EE+ A++E+ E+ EEE+ +        + +   A   +          +P+V +     
Sbjct: 1226 EEEMQAEAEEAEEGEEEDAA--------SSEVPAASPADSSNSPETETKEPEVEEEEEKP 1277

Query: 1072 QPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGE----DEEMADPMEDVIIR 1127
            +    + + ++             ++E +  + EEEE A  E    D+  AD  +D  + 
Sbjct: 1278 RVSEEQRQSEEE------------QQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE 1325

Query: 1128 NKKHQKLKHQKEAEEEELE 1146
            + K ++L+ Q   E+ + E
Sbjct: 1326 STKKKELEEQPTREDVKEE 1344



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 9/125 (7%)

Query: 922  QLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKR--LLPEEYHRVLVNIRKAEA 979
            Q+ ++ + KL+    +     L +L     R   F +++R  L+ +   ++ +N+R  + 
Sbjct: 710  QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDV 769

Query: 980  RAKRHR----ALSQAAVEEEEEEEEEE---EPAQGKGDSIEEILADSEDEEDNEEEERSR 1032
              +  R     +S + V EEEEEE EE   E  Q +   +E  +  S   E+ E++  S 
Sbjct: 770  DPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSV 829

Query: 1033 GKEQR 1037
              E++
Sbjct: 830  ESEKK 834



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%)

Query: 992  VEEEEEEEEEEE--PAQ-----GKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRS 1044
            ++EEEEEE+E E  P +        D +    +     +D EE+E S   +   + +  S
Sbjct: 1067 IDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVS 1126

Query: 1045 RAWLKEGGGDEPLNFLDPKVAQRVLATQPGP-GRGRKKDH---------GFKVSAD---- 1090
                +    D   + L+P  +  +   +  P G+ RK  H         GFK+S +    
Sbjct: 1127 LLRKR----DVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPV 1182

Query: 1091 -GRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144
              +  + E          +    E EE  +P ED+ +  ++ ++ + Q EAEE E
Sbjct: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE 1237


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 33/190 (17%)

Query: 989  QAAVEEEEEEEEE-----EEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQR 1043
            QA  EE EE EEE     E PA    DS      ++++ E  EEEE+ R  E+++ + + 
Sbjct: 1230 QAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEE 1289

Query: 1044 SRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNK 1103
             +        +EP    +P+  +   A        +  DH      DG L    E+   K
Sbjct: 1290 QQEL------EEP----EPEEEEDAAAE-----TAQNDDHDADDEDDGHL----ESTKKK 1330

Query: 1104 MEEEEGAKGEDEEMADPMEDVIIRN--KKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRP 1161
              EE+  + + +E     E  +  N  K  +K+K ++E E +  E  P +          
Sbjct: 1331 ELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTS------- 1383

Query: 1162 VAKKAMPGAE 1171
            V  + M G+E
Sbjct: 1384 VVSEQMAGSE 1393



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 26/176 (14%)

Query: 976  KAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKE 1035
            + E   ++ R   +    EEE++E EE   + + D+  E   + + + D+E++      +
Sbjct: 1269 EVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328

Query: 1036 QRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLII 1095
            +++L  Q +R  +KE  G +  +FLD  +              +K     K   +  L  
Sbjct: 1329 KKELEEQPTREDVKEEPGVQE-SFLDANM--------------QKSREKIKDKEETELDS 1373

Query: 1096 REEADGNK----MEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEI 1147
             EE   +      E+  G++ + EE +   E++I       +LK ++E    EL++
Sbjct: 1374 EEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELI-------ELKEEEEIPHSELDL 1422



 Score = 37.4 bits (85), Expect = 0.089
 Identities = 40/199 (20%), Positives = 85/199 (42%), Gaps = 27/199 (13%)

Query: 952  RKFGFELVKRLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDS 1011
            RK GF+L + ++P      ++    +  +A R   + ++   EE  E +E+ P   +   
Sbjct: 1169 RKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES---EETVEPKEDMPLPEERKE 1225

Query: 1012 IEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGDEPLNFLDPKVAQRVLAT 1071
             EE+ A++E+ E+ EEE+ +        + +   A   +          +P+V +     
Sbjct: 1226 EEEMQAEAEEAEEGEEEDAA--------SSEVPAASPADSSNSPETETKEPEVEEEEEKP 1277

Query: 1072 QPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEEEEGAKGE----DEEMADPMEDVIIR 1127
            +    + + ++             ++E +  + EEEE A  E    D+  AD  +D  + 
Sbjct: 1278 RVSEEQRQSEEE------------QQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLE 1325

Query: 1128 NKKHQKLKHQKEAEEEELE 1146
            + K ++L+ Q   E+ + E
Sbjct: 1326 STKKKELEEQPTREDVKEE 1344



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 9/125 (7%)

Query: 922  QLVMEAIGKLSDDMRRHFRMKLRNLFTKFIRKFGFELVKR--LLPEEYHRVLVNIRKAEA 979
            Q+ ++ + KL+    +     L +L     R   F +++R  L+ +   ++ +N+R  + 
Sbjct: 710  QISIKKLSKLTGICPQDITSTLHHLRMLDFRSDQFVIIRREKLIQDHMAKLQLNLRPVDV 769

Query: 980  RAKRHR----ALSQAAVEEEEEEEEEE---EPAQGKGDSIEEILADSEDEEDNEEEERSR 1032
              +  R     +S + V EEEEEE EE   E  Q +   +E  +  S   E+ E++  S 
Sbjct: 770  DPECLRWTPVIVSNSVVSEEEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSV 829

Query: 1033 GKEQR 1037
              E++
Sbjct: 830  ESEKK 834



 Score = 32.7 bits (73), Expect = 2.2
 Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 26/175 (14%)

Query: 992  VEEEEEEEEEEE--PAQ-----GKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRS 1044
            ++EEEEEE+E E  P +        D +    +     +D EE+E S   +   + +  S
Sbjct: 1067 IDEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVS 1126

Query: 1045 RAWLKEGGGDEPLNFLDPKVAQRVLATQPGP-GRGRKKDH---------GFKVSAD---- 1090
                +    D   + L+P  +  +   +  P G+ RK  H         GFK+S +    
Sbjct: 1127 LLRKR----DVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPV 1182

Query: 1091 -GRLIIREEADGNKMEEEEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEE 1144
              +  + E          +    E EE  +P ED+ +  ++ ++ + Q EAEE E
Sbjct: 1183 STQACVIEPIVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE 1237


>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
          Length = 1726

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 45/184 (24%), Positives = 81/184 (44%), Gaps = 16/184 (8%)

Query: 992  VEEEEEEEEEEEPA---QGKGDSIEEILADSEDEEDNEEEERSRG--KEQRKLARQRSRA 1046
            VEEE+++EEEEE     Q +  +++  + D +DE++ EE+E S     E     ++R R 
Sbjct: 31   VEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRT 90

Query: 1047 WLKEGGGDEPLNFLDPKVAQRVLATQPGPGRGRKKDHGFKVSADGRLIIREEADGNKMEE 1106
               +   D+  + ++  +  +V   + G    R K        D     +EE +   + E
Sbjct: 91   SFDDRLEDDDFDLIEENLGVKV---KRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAE 147

Query: 1107 EEGAKGEDEEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPP-QYQAGGSGIHRPVAKK 1165
            E    GE EE  + ME  +           ++E ++EE +I        G  + +P  +K
Sbjct: 148  EIFQDGEGEEGQEAMEAPMAP-------PEEEEEDDEESDIDDFIVDDDGQPLKKPKWRK 200

Query: 1166 AMPG 1169
             +PG
Sbjct: 201  KLPG 204



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 27/179 (15%)

Query: 995  EEEEEEEEEPAQGKGDSIEEILADSEDEEDNEEEERSRGKEQRKLARQRSRAWLKEGGGD 1054
            E E EE EE    +G+ +  +     +EED++EEE     E+  L  Q  +  LK    D
Sbjct: 6    ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEE-----EEENLDDQDEQGNLKGFIND 60

Query: 1055 EPLNFLDPKVAQRVLATQPGPGR---GRKKDHGFKVSADGRLIIREEADGNKMEEEEGAK 1111
            +     D    +    +  G      G KK    + S D RL   E+ D + +EE  G K
Sbjct: 61   DD----DEDEGEEDEGSDSGDSEDDVGHKKRK--RTSFDDRL---EDDDFDLIEENLGVK 111

Query: 1112 GED-------EEMADPMEDVIIRNKKHQKLKHQKEAEEEELEIPPQYQAGGSGIHRPVA 1163
             +        ++M+D  +D     +++ K +H+KEA  EE+    + + G   +  P+A
Sbjct: 112  VKRGQKYRRVKKMSDDEDD---DEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMA 167



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 19/69 (27%), Positives = 35/69 (50%)

Query: 961  RLLPEEYHRVLVNIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILADSE 1020
            RL  +++  +  N+     R +++R + + + +E+++EEE  +    K    EEI  D E
Sbjct: 95   RLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGE 154

Query: 1021 DEEDNEEEE 1029
             EE  E  E
Sbjct: 155  GEEGQEAME 163


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,268,773
Number of Sequences: 37866
Number of extensions: 2196148
Number of successful extensions: 30178
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 310
Number of HSP's successfully gapped in prelim test: 385
Number of HSP's that attempted gapping in prelim test: 15969
Number of HSP's gapped (non-prelim): 6846
length of query: 1236
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1122
effective length of database: 13,930,794
effective search space: 15630350868
effective search space used: 15630350868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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