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Search of human proteins with 223278368
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223278368 neuralized-like [Homo sapiens]
(574 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223278368 neuralized-like [Homo sapiens] 1185 0.0
gi|217416388 neuralized homolog 1B [Homo sapiens] 427 e-119
gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens] 60 4e-09
gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens] 60 4e-09
gi|18152787 neuralized-like protein 2 [Homo sapiens] 57 6e-08
gi|53729363 leucine rich repeat and sterile alpha motif containi... 54 5e-07
gi|53729361 leucine rich repeat and sterile alpha motif containi... 54 5e-07
gi|53729359 leucine rich repeat and sterile alpha motif containi... 54 5e-07
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens] 51 3e-06
gi|214010238 mahogunin, ring finger 1 isoform 4 [Homo sapiens] 49 2e-05
gi|214010236 mahogunin, ring finger 1 isoform 3 [Homo sapiens] 49 2e-05
gi|214010234 mahogunin, ring finger 1 isoform 2 [Homo sapiens] 49 2e-05
gi|44917608 mahogunin, ring finger 1 isoform 1 [Homo sapiens] 49 2e-05
gi|62865649 rififylin [Homo sapiens] 48 3e-05
gi|17432433 rififylin [Homo sapiens] 48 3e-05
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens] 48 3e-05
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa... 47 4e-05
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap... 47 4e-05
gi|58743365 ring finger protein 157 [Homo sapiens] 47 4e-05
gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens] 47 5e-05
gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens] 47 5e-05
gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo sap... 46 8e-05
gi|47716512 mex-3 homolog B [Homo sapiens] 46 8e-05
gi|147902746 MEX3A protein [Homo sapiens] 46 1e-04
gi|14042925 ring finger protein 26 [Homo sapiens] 45 1e-04
gi|11545910 livin inhibitor of apoptosis isoform beta [Homo sapi... 43 7e-04
gi|21536421 livin inhibitor of apoptosis isoform alpha [Homo sap... 43 7e-04
gi|45387949 ring finger and SPRY domain containing 1 [Homo sapiens] 42 0.001
gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo s... 42 0.002
gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo s... 42 0.002
>gi|223278368 neuralized-like [Homo sapiens]
Length = 574
Score = 1185 bits (3066), Expect = 0.0
Identities = 574/574 (100%), Positives = 574/574 (100%)
Query: 1 MGNNFSSIPSLPRGNPSRAPRGHPQNLKDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPA 60
MGNNFSSIPSLPRGNPSRAPRGHPQNLKDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPA
Sbjct: 1 MGNNFSSIPSLPRGNPSRAPRGHPQNLKDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPA 60
Query: 61 TPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGA 120
TPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGA
Sbjct: 61 TPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGA 120
Query: 121 LRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFH 180
LRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFH
Sbjct: 121 LRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFH 180
Query: 181 RINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLR 240
RINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLR
Sbjct: 181 RINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLR 240
Query: 241 READDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALR 300
READDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALR
Sbjct: 241 READDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALR 300
Query: 301 AGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTC 360
AGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTC
Sbjct: 301 AGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTC 360
Query: 361 DPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGM 420
DPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGM
Sbjct: 361 DPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGM 420
Query: 421 QLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDP 480
QLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDP
Sbjct: 421 QLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDP 480
Query: 481 LLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMC 540
LLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMC
Sbjct: 481 LLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMC 540
Query: 541 LCYACGLRLKKALHACCPICRRPIKDIIKTYRSS 574
LCYACGLRLKKALHACCPICRRPIKDIIKTYRSS
Sbjct: 541 LCYACGLRLKKALHACCPICRRPIKDIIKTYRSS 574
>gi|217416388 neuralized homolog 1B [Homo sapiens]
Length = 555
Score = 427 bits (1099), Expect = e-119
Identities = 237/526 (45%), Positives = 312/526 (59%), Gaps = 30/526 (5%)
Query: 65 FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLG 124
FH KG + +D + R+ SFCN +TF+ RP+ +YEQVRL++ + WSGALR G
Sbjct: 41 FHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFG 100
Query: 125 FTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRIND 184
FT+ DPS + +PKYACPDLV++ G+WAKALPE A ++A+W D+ GRVF+ +ND
Sbjct: 101 FTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVND 160
Query: 185 SAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDS---ELVLPDCLRPRSFTALRRPSL-- 239
+LF GV PLWAL+DVYG+T VQLL+S + + P L F+A PS
Sbjct: 161 GEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHD 220
Query: 240 -----RREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDL 294
E ++ ++ L L + A G A AA IP + PA L+ DL
Sbjct: 221 AANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADL 280
Query: 295 RFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALS 354
RFHA R G V + ++ VA R LVF+ RP+R E++FV+V R G A PGAL+
Sbjct: 281 RFHATR-GPDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALA 339
Query: 355 FGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHS-GDILGLVVNADGELHLSH 413
FG+T+CDPG LRP +LP P+AL+DRKE+W V R GP+ S GD L + G++ L
Sbjct: 340 FGITSCDPGVLRPNELPADPDALLDRKEYWVVARA-GPVPSGGDALSFTLRPGGDVLLGI 398
Query: 414 NGAAAGMQLCVDASQPLWMLFGLHGTIT-QIRILGSTILAERGIPSLPCSPASTPTSPSA 472
NG G LCVD +Q LW F + G + Q+R+LG +L SPA+T S S
Sbjct: 399 NGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLG----------TLQSSPATTTPSGSL 448
Query: 473 LGSR---LSDPLLSTCSSGPLGSSAGGTAPNSPVSLPESPV---TPGLGQWSDECTICYE 526
GS+ SD S S S+ TAP+SP+S P SPV G + ECT+C++
Sbjct: 449 SGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFD 508
Query: 527 HAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYR 572
VDTVIYTCGHMCLC++CGLRLK+ ACCPICRRPIKD+IK YR
Sbjct: 509 GEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYR 554
>gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens]
Length = 1562
Score = 60.5 bits (145), Expect = 4e-09
Identities = 97/443 (21%), Positives = 167/443 (37%), Gaps = 83/443 (18%)
Query: 63 LLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKITKKQCCWSG 119
LLFH G+ I + ++K +R+ F N + +NRP+ E ++I K WSG
Sbjct: 318 LLFHEKC-GTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSG 376
Query: 120 ALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVF 179
++ +G T+ +P+ + + + SG L F +D+
Sbjct: 377 SIEIGVTTHNPNSLEYPATMTNLQSGTIMMSG--CGILTNGKGTRREYCEFSLDELQEGD 434
Query: 180 H----RINDSAVMLFFSGV--RTADPL-----WALVDVYGLTRGVQLLDSELVLPDCLRP 228
H R ++SA+ F +G+ A PL + +VD+YG+ V ++ +
Sbjct: 435 HIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHN---------- 484
Query: 229 RSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPA 288
+D R + ++ P AAPAA +A P
Sbjct: 485 -----------NNHSDRLRRNNAILRALSPEGALRRAAPAA--------------QAEPE 519
Query: 289 QLDGDLRFHALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAETIFVKVTRSG 346
+ L FH G I E A H D+ +V +SR +R E V++ +
Sbjct: 520 R----LLFHP-NCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMV 574
Query: 347 GARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLH------------ 394
G++ GVTT +P L+ P + + + + G +H
Sbjct: 575 DKWAGSIEIGVTTHNPAYLQ------LPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHN 628
Query: 395 -----SGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRILGST 449
+GD +G+V DG LH NG G + ++ + L+G Q I+
Sbjct: 629 LDRLKAGDTVGVVRREDGTLHFFVNGMTQG-PAAWNVPPGVYAVVDLYGQAAQATIVDDV 687
Query: 450 ILAERGIPSLPCSPASTPTSPSA 472
+A P + +P+SPS+
Sbjct: 688 EVAPVPEPLPEGNNQVSPSSPSS 710
Score = 55.5 bits (132), Expect = 1e-07
Identities = 89/423 (21%), Positives = 157/423 (37%), Gaps = 87/423 (20%)
Query: 65 FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLG 124
FH T G + ++ R A + + + FS + + E +K+ + W+G+LRLG
Sbjct: 916 FHS-TCGKNVTLEEDGTRAVRAAGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRLG 974
Query: 125 FTSKDPSRIHPDS------LPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV 178
T+ P + P + LP + P+L +++ + + E +G + GR
Sbjct: 975 LTTLAPGEMGPGAGGGGPGLPP-SLPELRTKTTWMVSSC--EVRRDGQLQRM---NYGRN 1028
Query: 179 FHRIN-----------DSAVMLFFSG-------VRTADPLWALVDVYGLTRGVQLLDSEL 220
R+ D + + G A +WA++D+YG RGV ++ S
Sbjct: 1029 LERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTR 1088
Query: 221 VLPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNS 280
+ E++ + D G + DE ++ L
Sbjct: 1089 L-------------------EESEGTQPPSPSSDTGSEGEEDDEGE--------EHGLGG 1121
Query: 281 QHSRALPAQLDGDLRFHALRAGAHVRILD-EQTVARVEHGRDERALVFTSRPVRVAETIF 339
Q+ + L H G ++ + + +T RV + +V ++P+ +
Sbjct: 1122 QNEVGIIPTTLEFLENH----GKNILLSNGNRTATRV--ASYNQGIVVINQPLVPQLLVQ 1175
Query: 340 VKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWA------------VC 387
V++ +L GV TC P L F A ++ W +C
Sbjct: 1176 VRIDFLNRQWTSSLVLGVITCAPERLN-----FPASACALKRAAWLLRGRGVFHNGLKIC 1230
Query: 388 RVPGP----LHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQI 443
GP G ILGL +++ G LHL NG G+ + D QP L L+G Q+
Sbjct: 1231 EKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQGVAV-PDVPQPCHALVDLYGQCEQV 1289
Query: 444 RIL 446
I+
Sbjct: 1290 TIV 1292
Score = 52.8 bits (125), Expect = 9e-07
Identities = 103/458 (22%), Positives = 164/458 (35%), Gaps = 102/458 (22%)
Query: 54 PSGGLPATPLLFHPHTKGSQILMDLSHKAVKR--QASFCNAITFSNRPVLIYEQVRLKIT 111
PS G + L FH + ++ + A++ ++ F +AI SNR + E + I
Sbjct: 708 PSSGAGGSDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQ 767
Query: 112 KKQCCWSGALRLGFTSKDPSRIH-PDSLPKY------ACPDLVSQSGFWAK---ALPEEF 161
K WSG++ G T+ P + P+++ + Q G + +
Sbjct: 768 KMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDA 827
Query: 162 ANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYG------LTRGVQL 215
G I KG + + IN SG+ ++A+VD+YG +T
Sbjct: 828 LGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGP 887
Query: 216 LDSELVLPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQ 275
+D+ L + +SF P A A S C NV
Sbjct: 888 MDNSLATSNTATEKSF-----PLHSPVAGVAHRFHSTCGKNV------------------ 924
Query: 276 NSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVA 335
+L +RA+ A A HG LVF+++ +R
Sbjct: 925 -TLEEDGTRAVRA-------------------------AGYAHG-----LVFSTKELRAE 953
Query: 336 ETIFVKVTRSGGARPGALSFGVTTCDPGTLRP---ADLPFSPEALVD--RKEFWAV--CR 388
E VKV G+L G+TT PG + P P P +L + K W V C
Sbjct: 954 EVFEVKVEELDEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCE 1013
Query: 389 V--PGPLHS------------GDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLF 434
V G L G +G+ AD +H+ +G G ++ +W +
Sbjct: 1014 VRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMG-PAATGIAKNVWAVL 1072
Query: 435 GLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSA 472
L+G + + I+ ST L E S + P SPS+
Sbjct: 1073 DLYGPVRGVSIVSSTRLEE--------SEGTQPPSPSS 1102
Score = 50.4 bits (119), Expect = 4e-06
Identities = 91/430 (21%), Positives = 159/430 (36%), Gaps = 108/430 (25%)
Query: 63 LLFHPHTKGSQILMDLSHKAVKRQAS--FCNAITFSNRPVLIYEQVRLKITKKQCCWSGA 120
LLFHP+ + A++ A+ F + + S+R + E +++I K W+G+
Sbjct: 521 LLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGS 580
Query: 121 LRLGFTSKDPSRIH-PDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVF 179
+ +G T+ +P+ + P ++ +SG W N I+ D+ G
Sbjct: 581 IEIGVTTHNPAYLQLPSTMTNL-------RSGTWMMTGNGVMHNGTTIL----DEYGHNL 629
Query: 180 HRIN-----------DSAVMLFFSGVRTADPLW-------ALVDVYGLTRGVQLLDSELV 221
R+ D + F +G+ W A+VD+YG ++D V
Sbjct: 630 DRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVDDVEV 689
Query: 222 LPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQ 281
P VP P+P+ N+Q
Sbjct: 690 AP---------------------------------VPE------------PLPEG--NNQ 702
Query: 282 HSRALPAQLDG--DLRFHALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAET 337
S + P+ G DLRFH L G++ I + A + R E A+V ++R +R E
Sbjct: 703 VSPSSPSSGAGGSDLRFHQLH-GSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGEL 761
Query: 338 IFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRK-EFWAVCRVP------ 390
+ + + G++ GVT +RP DL F P + D + W +
Sbjct: 762 FEIVIQKMVDRWSGSIEAGVTA-----IRPEDLEF-PNTMTDIDYDTWMLSGTAIMQDGN 815
Query: 391 ----------GPLHSGDILGLVVNADGELHLSHNGAAAGMQLC-VDASQPLWMLFGLHGT 439
L +G +G++ A G+LH NG G + + ++ + L+G
Sbjct: 816 TMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQ 875
Query: 440 ITQIRILGST 449
Q+ I +T
Sbjct: 876 CVQVSITNAT 885
Score = 47.4 bits (111), Expect = 4e-05
Identities = 49/183 (26%), Positives = 71/183 (38%), Gaps = 22/183 (12%)
Query: 311 QTVARVEHGRD-ERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPAD 369
+T R + G++ LV + P+R V++ R + G++ GVT DP L D
Sbjct: 59 RTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVL---D 115
Query: 370 LPFSPEALVDRKEFWAVCRV--------------PGPLHSGDILGLVVNADGELHLSHNG 415
P S L + C V L GD +G+ GEL L NG
Sbjct: 116 FPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNG 175
Query: 416 AAAGMQLCVDASQPLWMLFGLHGTITQIRILGST--ILAERGIPSLPCSPASTPTSPSAL 473
G+ +W + L+G TQI +L IP+ P P + PT SAL
Sbjct: 176 RDCGV-AATGLPPRVWAVVDLYGKCTQITVLPPEPGFSPPTPIPTPPLEPLA-PTEDSAL 233
Query: 474 GSR 476
+
Sbjct: 234 AEQ 236
Score = 47.0 bits (110), Expect = 5e-05
Identities = 91/440 (20%), Positives = 156/440 (35%), Gaps = 91/440 (20%)
Query: 55 SGGLPATPLLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKIT 111
+GGL + L HP T G + + + +RQ F + + S P+ ++I
Sbjct: 35 NGGLGSGGEL-HPRT-GRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRID 92
Query: 112 KKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWA----------KALPEEF 161
+K WSG++ +G T+ DPS + P A + G W +++ EE+
Sbjct: 93 RKVNSWSGSIEIGVTALDPSVL---DFPSSATG---LKGGSWVVSGCSVLRDGRSVLEEY 146
Query: 162 AN------EGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQL 215
EG+ + G + +N + +G+ +WA+VD+YG + +
Sbjct: 147 GQDLDQLGEGDRVGVERTVAGELRLWVNGRDCGVAATGLPPR--VWAVVDLYGKCTQITV 204
Query: 216 LDSE------------------------------------LVLPDCLRPRSFTALRRPSL 239
L E +V P RP +F SL
Sbjct: 205 LPPEPGFSPPTPIPTPPLEPLAPTEDSALAEQGTSADEAFMVSPAQARPETFPN----SL 260
Query: 240 RREADDARLSVSLCDLN--VPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFH 297
D A + +S N + +G P L S + P D
Sbjct: 261 ESHNDFANMELSEVVSNTILSAYNGGLLNVNLSSPPAGEGLGSSGAATSPILTSNDALLF 320
Query: 298 ALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAETIFVKVTRSGGARPGALSF 355
+ G +++ + A DE +V T+RP+R E +++ + G++
Sbjct: 321 HEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEI 380
Query: 356 GVTTCDPGTLR-PADLPFSPEALV-------------DRKEFWAVCRVP-GPLHSGDILG 400
GVTT +P +L PA + + R+E+ C L GD +G
Sbjct: 381 GVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREY---CEFSLDELQEGDHIG 437
Query: 401 LVVNADGELHLSHNGAAAGM 420
L ++ LH NG G+
Sbjct: 438 LTRKSNSALHFFINGIDQGV 457
Score = 41.2 bits (95), Expect = 0.003
Identities = 49/182 (26%), Positives = 76/182 (41%), Gaps = 30/182 (16%)
Query: 56 GGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVL--IYEQVRLKITKK 113
G +P T H G IL+ ++ R AS+ I N+P++ + QVR+ +
Sbjct: 1126 GIIPTTLEFLENH--GKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNR 1183
Query: 114 QCCWSGALRLGFTSKDPSRIHPDSLPKYAC-----PDLVSQSGFWAKALP--EEF----- 161
Q W+ +L LG + P R+ + P AC L+ G + L E+F
Sbjct: 1184 Q--WTSSLVLGVITCAPERL---NFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLD 1238
Query: 162 -ANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTAD---PLWALVDVYGLTRGVQLLD 217
EG I+ +D G + +N GV D P ALVD+YG V +++
Sbjct: 1239 TCPEGTILGLRLDSSGGLHLHVNG-----VDQGVAVPDVPQPCHALVDLYGQCEQVTIVN 1293
Query: 218 SE 219
E
Sbjct: 1294 PE 1295
Score = 29.6 bits (65), Expect = 7.9
Identities = 13/26 (50%), Positives = 16/26 (61%)
Query: 482 LSTCSSGPLGSSAGGTAPNSPVSLPE 507
L+T + G +G AGG P P SLPE
Sbjct: 975 LTTLAPGEMGPGAGGGGPGLPPSLPE 1000
>gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens]
Length = 1560
Score = 60.5 bits (145), Expect = 4e-09
Identities = 97/443 (21%), Positives = 167/443 (37%), Gaps = 83/443 (18%)
Query: 63 LLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKITKKQCCWSG 119
LLFH G+ I + ++K +R+ F N + +NRP+ E ++I K WSG
Sbjct: 318 LLFHEKC-GTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSG 376
Query: 120 ALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVF 179
++ +G T+ +P+ + + + SG L F +D+
Sbjct: 377 SIEIGVTTHNPNSLEYPATMTNLQSGTIMMSG--CGILTNGKGTRREYCEFSLDELQEGD 434
Query: 180 H----RINDSAVMLFFSGV--RTADPL-----WALVDVYGLTRGVQLLDSELVLPDCLRP 228
H R ++SA+ F +G+ A PL + +VD+YG+ V ++ +
Sbjct: 435 HIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHN---------- 484
Query: 229 RSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPA 288
+D R + ++ P AAPAA +A P
Sbjct: 485 -----------NNHSDRLRRNNAILRALSPEGALRRAAPAA--------------QAEPE 519
Query: 289 QLDGDLRFHALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAETIFVKVTRSG 346
+ L FH G I E A H D+ +V +SR +R E V++ +
Sbjct: 520 R----LLFHP-NCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMV 574
Query: 347 GARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLH------------ 394
G++ GVTT +P L+ P + + + + G +H
Sbjct: 575 DKWAGSIEIGVTTHNPAYLQ------LPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHN 628
Query: 395 -----SGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRILGST 449
+GD +G+V DG LH NG G + ++ + L+G Q I+
Sbjct: 629 LDRLKAGDTVGVVRREDGTLHFFVNGMTQG-PAAWNVPPGVYAVVDLYGQAAQATIVDDV 687
Query: 450 ILAERGIPSLPCSPASTPTSPSA 472
+A P + +P+SPS+
Sbjct: 688 EVAPVPEPLPEGNNQVSPSSPSS 710
Score = 55.5 bits (132), Expect = 1e-07
Identities = 89/423 (21%), Positives = 157/423 (37%), Gaps = 87/423 (20%)
Query: 65 FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLG 124
FH T G + ++ R A + + + FS + + E +K+ + W+G+LRLG
Sbjct: 914 FHS-TCGKNVTLEEDGTRAVRAAGYAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRLG 972
Query: 125 FTSKDPSRIHPDS------LPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRV 178
T+ P + P + LP + P+L +++ + + E +G + GR
Sbjct: 973 LTTLAPGEMGPGAGGGGPGLPP-SLPELRTKTTWMVSSC--EVRRDGQLQRM---NYGRN 1026
Query: 179 FHRIN-----------DSAVMLFFSG-------VRTADPLWALVDVYGLTRGVQLLDSEL 220
R+ D + + G A +WA++D+YG RGV ++ S
Sbjct: 1027 LERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTR 1086
Query: 221 VLPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNS 280
+ E++ + D G + DE ++ L
Sbjct: 1087 L-------------------EESEGTQPPSPSSDTGSEGEEDDEGE--------EHGLGG 1119
Query: 281 QHSRALPAQLDGDLRFHALRAGAHVRILD-EQTVARVEHGRDERALVFTSRPVRVAETIF 339
Q+ + L H G ++ + + +T RV + +V ++P+ +
Sbjct: 1120 QNEVGIIPTTLEFLENH----GKNILLSNGNRTATRV--ASYNQGIVVINQPLVPQLLVQ 1173
Query: 340 VKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWA------------VC 387
V++ +L GV TC P L F A ++ W +C
Sbjct: 1174 VRIDFLNRQWTSSLVLGVITCAPERLN-----FPASACALKRAAWLLRGRGVFHNGLKIC 1228
Query: 388 RVPGP----LHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQI 443
GP G ILGL +++ G LHL NG G+ + D QP L L+G Q+
Sbjct: 1229 EKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQGVAV-PDVPQPCHALVDLYGQCEQV 1287
Query: 444 RIL 446
I+
Sbjct: 1288 TIV 1290
Score = 52.4 bits (124), Expect = 1e-06
Identities = 92/429 (21%), Positives = 158/429 (36%), Gaps = 108/429 (25%)
Query: 63 LLFHPHTKGSQILMDLSHKAVKRQAS--FCNAITFSNRPVLIYEQVRLKITKKQCCWSGA 120
LLFHP+ + A++ A+ F + + S+R + E +++I K W+G+
Sbjct: 521 LLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGS 580
Query: 121 LRLGFTSKDPSRIH-PDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVF 179
+ +G T+ +P+ + P ++ +SG W N I+ D+ G
Sbjct: 581 IEIGVTTHNPAYLQLPSTMTNL-------RSGTWMMTGNGVMHNGTTIL----DEYGHNL 629
Query: 180 HRIN-----------DSAVMLFFSGVRTADPLW-------ALVDVYGLTRGVQLLDSELV 221
R+ D + F +G+ W A+VD+YG ++D V
Sbjct: 630 DRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVDDVEV 689
Query: 222 LPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQ 281
P VP P+P+ N+Q
Sbjct: 690 AP---------------------------------VPE------------PLPEG--NNQ 702
Query: 282 HSRALPAQLDG--DLRFHALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAET 337
S + P+ G DLRFH L G++ I + A + R E A+V ++R +R E
Sbjct: 703 VSPSSPSSGAGGSDLRFHQLH-GSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGEL 761
Query: 338 IFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRK-EFWAVCRVP------ 390
+ + + G++ GVT +RP DL F P + D + W +
Sbjct: 762 FEIVIQKMVDRWSGSIEAGVTA-----IRPEDLEF-PNTMTDIDYDTWMLSGTAIMQDGN 815
Query: 391 ----------GPLHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTI 440
L +G +G++ A G+LH NG G C ++ + L+G
Sbjct: 816 TMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQG-AACSGLPPEVYAVVDLYGQC 874
Query: 441 TQIRILGST 449
Q+ I +T
Sbjct: 875 VQVSITNAT 883
Score = 49.7 bits (117), Expect = 7e-06
Identities = 104/459 (22%), Positives = 162/459 (35%), Gaps = 106/459 (23%)
Query: 54 PSGGLPATPLLFHPHTKGSQILMDLSHKAVKR--QASFCNAITFSNRPVLIYEQVRLKIT 111
PS G + L FH + ++ + A++ ++ F +AI SNR + E + I
Sbjct: 708 PSSGAGGSDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQ 767
Query: 112 KKQCCWSGALRLGFTSKDPSRIH-PDSLPK------YACPDLVSQSGFWAK---ALPEEF 161
K WSG++ G T+ P + P+++ + Q G + +
Sbjct: 768 KMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDA 827
Query: 162 ANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYG------LTRGVQL 215
G I KG + + IN SG+ ++A+VD+YG +T
Sbjct: 828 LGTGARIGMMRTAKGDLHYFINGQDQGAACSGL--PPEVYAVVDLYGQCVQVSITNATGP 885
Query: 216 LDSELVLPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNVP-GADGDEAAPAAGCPIP 274
+D+ L + +SF P A A S C NV DG A AAG
Sbjct: 886 MDNSLATSNTATEKSF-----PLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRAAG---- 936
Query: 275 QNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRV 334
HG LVF+++ +R
Sbjct: 937 -----------------------------------------YAHG-----LVFSTKELRA 950
Query: 335 AETIFVKVTRSGGARPGALSFGVTTCDPGTLRP---ADLPFSPEALVD--RKEFWAV--C 387
E VKV G+L G+TT PG + P P P +L + K W V C
Sbjct: 951 EEVFEVKVEELDEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSC 1010
Query: 388 RV--PGPLHS------------GDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWML 433
V G L G +G+ AD +H+ +G G ++ +W +
Sbjct: 1011 EVRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMG-PAATGIAKNVWAV 1069
Query: 434 FGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSA 472
L+G + + I+ ST L E S + P SPS+
Sbjct: 1070 LDLYGPVRGVSIVSSTRLEE--------SEGTQPPSPSS 1100
Score = 47.4 bits (111), Expect = 4e-05
Identities = 49/183 (26%), Positives = 71/183 (38%), Gaps = 22/183 (12%)
Query: 311 QTVARVEHGRD-ERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPAD 369
+T R + G++ LV + P+R V++ R + G++ GVT DP L D
Sbjct: 59 RTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVL---D 115
Query: 370 LPFSPEALVDRKEFWAVCRV--------------PGPLHSGDILGLVVNADGELHLSHNG 415
P S L + C V L GD +G+ GEL L NG
Sbjct: 116 FPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNG 175
Query: 416 AAAGMQLCVDASQPLWMLFGLHGTITQIRILGST--ILAERGIPSLPCSPASTPTSPSAL 473
G+ +W + L+G TQI +L IP+ P P + PT SAL
Sbjct: 176 RDCGV-AATGLPPRVWAVVDLYGKCTQITVLPPEPGFSPPTPIPTPPLEPLA-PTEDSAL 233
Query: 474 GSR 476
+
Sbjct: 234 AEQ 236
Score = 47.0 bits (110), Expect = 5e-05
Identities = 91/440 (20%), Positives = 156/440 (35%), Gaps = 91/440 (20%)
Query: 55 SGGLPATPLLFHPHTKGSQILMDLSHKAVKRQA---SFCNAITFSNRPVLIYEQVRLKIT 111
+GGL + L HP T G + + + +RQ F + + S P+ ++I
Sbjct: 35 NGGLGSGGEL-HPRT-GRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRID 92
Query: 112 KKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWA----------KALPEEF 161
+K WSG++ +G T+ DPS + P A + G W +++ EE+
Sbjct: 93 RKVNSWSGSIEIGVTALDPSVL---DFPSSATG---LKGGSWVVSGCSVLRDGRSVLEEY 146
Query: 162 AN------EGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQL 215
EG+ + G + +N + +G+ +WA+VD+YG + +
Sbjct: 147 GQDLDQLGEGDRVGVERTVAGELRLWVNGRDCGVAATGLPPR--VWAVVDLYGKCTQITV 204
Query: 216 LDSE------------------------------------LVLPDCLRPRSFTALRRPSL 239
L E +V P RP +F SL
Sbjct: 205 LPPEPGFSPPTPIPTPPLEPLAPTEDSALAEQGTSADEAFMVSPAQARPETFPN----SL 260
Query: 240 RREADDARLSVSLCDLN--VPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFH 297
D A + +S N + +G P L S + P D
Sbjct: 261 ESHNDFANMELSEVVSNTILSAYNGGLLNVNLSSPPAGEGLGSSGAATSPILTSNDALLF 320
Query: 298 ALRAGAHVRILDEQTVARVEHGRDE--RALVFTSRPVRVAETIFVKVTRSGGARPGALSF 355
+ G +++ + A DE +V T+RP+R E +++ + G++
Sbjct: 321 HEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEI 380
Query: 356 GVTTCDPGTLR-PADLPFSPEALV-------------DRKEFWAVCRVP-GPLHSGDILG 400
GVTT +P +L PA + + R+E+ C L GD +G
Sbjct: 381 GVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREY---CEFSLDELQEGDHIG 437
Query: 401 LVVNADGELHLSHNGAAAGM 420
L ++ LH NG G+
Sbjct: 438 LTRKSNSALHFFINGIDQGV 457
Score = 41.2 bits (95), Expect = 0.003
Identities = 49/182 (26%), Positives = 76/182 (41%), Gaps = 30/182 (16%)
Query: 56 GGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVL--IYEQVRLKITKK 113
G +P T H G IL+ ++ R AS+ I N+P++ + QVR+ +
Sbjct: 1124 GIIPTTLEFLENH--GKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNR 1181
Query: 114 QCCWSGALRLGFTSKDPSRIHPDSLPKYAC-----PDLVSQSGFWAKALP--EEF----- 161
Q W+ +L LG + P R+ + P AC L+ G + L E+F
Sbjct: 1182 Q--WTSSLVLGVITCAPERL---NFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLD 1236
Query: 162 -ANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTAD---PLWALVDVYGLTRGVQLLD 217
EG I+ +D G + +N GV D P ALVD+YG V +++
Sbjct: 1237 TCPEGTILGLRLDSSGGLHLHVNG-----VDQGVAVPDVPQPCHALVDLYGQCEQVTIVN 1291
Query: 218 SE 219
E
Sbjct: 1292 PE 1293
Score = 29.6 bits (65), Expect = 7.9
Identities = 13/26 (50%), Positives = 16/26 (61%)
Query: 482 LSTCSSGPLGSSAGGTAPNSPVSLPE 507
L+T + G +G AGG P P SLPE
Sbjct: 973 LTTLAPGEMGPGAGGGGPGLPPSLPE 998
>gi|18152787 neuralized-like protein 2 [Homo sapiens]
Length = 285
Score = 56.6 bits (135), Expect = 6e-08
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 62 PLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGAL 121
P FH G+ I +D S R SF + + FS P+ + ++I +K+ W G L
Sbjct: 23 PTRFH-RVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHL 81
Query: 122 RLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKAL 157
RLG T+ DP+ + P +P+++ PDLV+ W A+
Sbjct: 82 RLGLTALDPASLAP--VPEFSLPDLVNLGHTWVFAI 115
Score = 31.6 bits (70), Expect = 2.1
Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 193 GVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRREADD 245
G+ A PL+A+VDV+ T+ V+L+ E LP L+ ++R + R A D
Sbjct: 219 GLPAAQPLYAVVDVFASTKSVRLVQLEYGLPS-LQTLCRLVIQRSMVHRLAID 270
Score = 30.8 bits (68), Expect = 3.5
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 11/94 (11%)
Query: 295 RFHALRAGAHVRILDEQTVA-RVE---HGRDERALVFTSRPVRVAETIFVKVTRSGGARP 350
RFH + GA++R+ T A RVE HG + F+ P+ + V++
Sbjct: 25 RFHRVH-GANIRVDPSGTRATRVESFAHG-----VCFSREPLAPGQVFLVEIEEKELGWC 78
Query: 351 GALSFGVTTCDPGTLRPADLPFSPEALVDRKEFW 384
G L G+T DP +L P FS LV+ W
Sbjct: 79 GHLRLGLTALDPASLAPVP-EFSLPDLVNLGHTW 111
>gi|53729363 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 53.5 bits (127), Expect = 5e-07
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 6/87 (6%)
Query: 489 PLGSSAGGTAPNSPVSLPESPVTPG-LGQWSDECTICYEHAVDTVIYTCGHMCLCYACGL 547
P+G TAP P P L + EC +C E + CGH+C C C
Sbjct: 642 PMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQ 701
Query: 548 RLKKALHACCPICRRPIKDIIKTYRSS 574
L+ CP+CR+ I ++ Y SS
Sbjct: 702 PLR-----TCPLCRQDIAQRLRIYHSS 723
>gi|53729361 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 53.5 bits (127), Expect = 5e-07
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 6/87 (6%)
Query: 489 PLGSSAGGTAPNSPVSLPESPVTPG-LGQWSDECTICYEHAVDTVIYTCGHMCLCYACGL 547
P+G TAP P P L + EC +C E + CGH+C C C
Sbjct: 642 PMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQ 701
Query: 548 RLKKALHACCPICRRPIKDIIKTYRSS 574
L+ CP+CR+ I ++ Y SS
Sbjct: 702 PLR-----TCPLCRQDIAQRLRIYHSS 723
>gi|53729359 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 53.5 bits (127), Expect = 5e-07
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 6/87 (6%)
Query: 489 PLGSSAGGTAPNSPVSLPESPVTPG-LGQWSDECTICYEHAVDTVIYTCGHMCLCYACGL 547
P+G TAP P P L + EC +C E + CGH+C C C
Sbjct: 642 PMGEVVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQ 701
Query: 548 RLKKALHACCPICRRPIKDIIKTYRSS 574
L+ CP+CR+ I ++ Y SS
Sbjct: 702 PLR-----TCPLCRQDIAQRLRIYHSS 723
>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
Length = 651
Score = 51.2 bits (121), Expect = 3e-06
Identities = 37/141 (26%), Positives = 48/141 (34%), Gaps = 31/141 (21%)
Query: 462 SPASTPTSPSALGSRLSDPLLSTCSSGPLG-----------SSAGGTAPNSPVSLPESPV 510
+P +PT P G RL PL + P+G S GG A ++ SLP SP
Sbjct: 510 TPRHSPTLPEPGGLRLELPLSRRGAPDPVGALSWRPPQGPVSFPGGAAFSTATSLPSSPA 569
Query: 511 TPGLGQWSD--------------------ECTICYEHAVDTVIYTCGHMCLCYACGLRLK 550
EC +C E V + CGH C C +R+
Sbjct: 570 AAACAPLDSGASENSRKPPSASSAPALARECVVCAEGEVMAALVPCGHNLFCMDCAVRIC 629
Query: 551 KALHACCPICRRPIKDIIKTY 571
CP CR P I +
Sbjct: 630 GKSEPECPACRTPATQAIHIF 650
>gi|214010238 mahogunin, ring finger 1 isoform 4 [Homo sapiens]
Length = 531
Score = 48.5 bits (114), Expect = 2e-05
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 518 SDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIK 569
S+EC +C DT+I C H+CLC +C L+ + CPICR P + +++
Sbjct: 276 SNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANN-CPICRLPFRALLQ 326
>gi|214010236 mahogunin, ring finger 1 isoform 3 [Homo sapiens]
Length = 552
Score = 48.5 bits (114), Expect = 2e-05
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 518 SDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIK 569
S+EC +C DT+I C H+CLC +C L+ + CPICR P + +++
Sbjct: 275 SNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANN-CPICRLPFRALLQ 325
>gi|214010234 mahogunin, ring finger 1 isoform 2 [Homo sapiens]
Length = 555
Score = 48.5 bits (114), Expect = 2e-05
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 518 SDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIK 569
S+EC +C DT+I C H+CLC +C L+ + CPICR P + +++
Sbjct: 276 SNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANN-CPICRLPFRALLQ 326
>gi|44917608 mahogunin, ring finger 1 isoform 1 [Homo sapiens]
Length = 576
Score = 48.5 bits (114), Expect = 2e-05
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 518 SDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIK 569
S+EC +C DT+I C H+CLC +C L+ + CPICR P + +++
Sbjct: 275 SNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANN-CPICRLPFRALLQ 325
>gi|62865649 rififylin [Homo sapiens]
Length = 363
Score = 47.8 bits (112), Expect = 3e-05
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 5/53 (9%)
Query: 521 CTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRS 573
C IC + +D V+ CGHM C CG R+ + CPICR+ + + +RS
Sbjct: 316 CKICMDSPIDCVLLECGHMVTCTKCGKRMNE-----CPICRQYVIRAVHVFRS 363
>gi|17432433 rififylin [Homo sapiens]
Length = 363
Score = 47.8 bits (112), Expect = 3e-05
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 5/53 (9%)
Query: 521 CTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRS 573
C IC + +D V+ CGHM C CG R+ + CPICR+ + + +RS
Sbjct: 316 CKICMDSPIDCVLLECGHMVTCTKCGKRMNE-----CPICRQYVIRAVHVFRS 363
>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
Length = 659
Score = 47.8 bits (112), Expect = 3e-05
Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 28/132 (21%)
Query: 458 SLPCSPASTPTSPSALGSRL-----SDP-----------LLSTCSSGP--LGSSAGGTAP 499
S P +P +PT P ++ L SDP + S+G SS GG+
Sbjct: 537 SQPSTPRLSPTFPESIEHPLARRVRSDPPSTGNHVGLPIYIPAFSNGTNSYSSSNGGSTS 596
Query: 500 NSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPI 559
+SP PES + +C IC+E+ V + CGH C C ++ + CP+
Sbjct: 597 SSP---PES-------RRKHDCVICFENEVIAALVPCGHNLFCMECANKICEKRTPSCPV 646
Query: 560 CRRPIKDIIKTY 571
C+ + I+ +
Sbjct: 647 CQTAVTQAIQIH 658
>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 47.4 bits (111), Expect = 4e-05
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 499 PNSPVSLPESPVTPGLGQWSDE--CTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHAC 556
P VS + PV L + +E C +C + V V CGH+ +C C L+K
Sbjct: 535 PTEDVS--DLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRK----- 587
Query: 557 CPICRRPIKDIIKTYRS 573
CPICR IK ++T+ S
Sbjct: 588 CPICRSTIKGTVRTFLS 604
>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 47.4 bits (111), Expect = 4e-05
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 499 PNSPVSLPESPVTPGLGQWSDE--CTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHAC 556
P VS + PV L + +E C +C + V V CGH+ +C C L+K
Sbjct: 535 PTEDVS--DLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRK----- 587
Query: 557 CPICRRPIKDIIKTYRS 573
CPICR IK ++T+ S
Sbjct: 588 CPICRSTIKGTVRTFLS 604
>gi|58743365 ring finger protein 157 [Homo sapiens]
Length = 679
Score = 47.4 bits (111), Expect = 4e-05
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Query: 518 SDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIK 569
S EC +C DT+I C H+CLC C L+ + CPICR P + +++
Sbjct: 274 SAECVVCLSDVRDTLILPCRHLCLCNTCADTLRYQANN-CPICRLPFRALLQ 324
>gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]
Length = 373
Score = 47.0 bits (110), Expect = 5e-05
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 5/53 (9%)
Query: 521 CTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRS 573
C IC + +D V+ CGHM C CG R+ + CPICR+ + + ++S
Sbjct: 326 CRICMDAVIDCVLLECGHMVTCTKCGKRMSE-----CPICRQYVVRAVHVFKS 373
>gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]
Length = 372
Score = 47.0 bits (110), Expect = 5e-05
Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 5/53 (9%)
Query: 521 CTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRS 573
C IC + +D V+ CGHM C CG R+ + CPICR+ + + ++S
Sbjct: 325 CRICMDAVIDCVLLECGHMVTCTKCGKRMSE-----CPICRQYVVRAVHVFKS 372
>gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
sapiens]
Length = 618
Score = 46.2 bits (108), Expect = 8e-05
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 5/53 (9%)
Query: 521 CTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRS 573
C +C + V V CGH+ +C C L+K CPICR IK ++T+ S
Sbjct: 571 CKVCMDKEVSVVFIPCGHLVVCQECAPSLRK-----CPICRGIIKGTVRTFLS 618
>gi|47716512 mex-3 homolog B [Homo sapiens]
Length = 569
Score = 46.2 bits (108), Expect = 8e-05
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 492 SSAGGTAPNSPVSLPESPVTPGLGQ-WSDECTICYEHAVDTVIYTCGHMCLCYACGLRLK 550
S G++ +S S S + GL + S +C++C+E V + CGH C C R+
Sbjct: 488 SDTSGSSSSSSSSSSSSSSSSGLRRKGSRDCSVCFESEVIAALVPCGHNLFCMECANRIC 547
Query: 551 KALHACCPICRRPIKDIIKTY 571
+ CP+C + I+ +
Sbjct: 548 EKSEPECPVCHTAVTQAIRIF 568
>gi|147902746 MEX3A protein [Homo sapiens]
Length = 520
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 21/139 (15%)
Query: 451 LAERGIPSLPCSPASTPTSPSALGSRLSDPLLSTCSSGPLGS------SAGGTAPNSPVS 504
+AE P +TPTS + S + +GP G+ SAG P
Sbjct: 384 VAETSPPLWAGQENATPTSVLFSSASSSSSSSAKARAGPPGAHRSPATSAGPELAGLPRR 443
Query: 505 LPESPV------------TPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKA 552
P P+ +PG G+ +C +C+E V + CGH C C +R+ +
Sbjct: 444 PPGEPLQGFSKLGGGGLRSPGGGR---DCMVCFESEVTAALVPCGHNLFCMECAVRICER 500
Query: 553 LHACCPICRRPIKDIIKTY 571
CP+C I+ +
Sbjct: 501 TDPECPVCHITATQAIRIF 519
>gi|14042925 ring finger protein 26 [Homo sapiens]
Length = 433
Score = 45.4 bits (106), Expect = 1e-04
Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Query: 520 ECTICYEHAVDTVIYTCGHMCLCYACG--LRLKKALHACCPICRRPIKDIIKTY 571
+C IC + + ++ C H+CLC AC L H CP+CRR I + Y
Sbjct: 379 KCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRRGILQTLNVY 432
>gi|11545910 livin inhibitor of apoptosis isoform beta [Homo
sapiens]
Length = 280
Score = 43.1 bits (100), Expect = 7e-04
Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 10/55 (18%)
Query: 521 CTICYEHAVDTVIYTCGHMCLCYAC--GLRLKKALHACCPICRRPIKDIIKTYRS 573
C +C + AV V CGH+ +C C GL+L CPICR P++ ++T+ S
Sbjct: 234 CKVCLDRAVSIVFVPCGHL-VCAECAPGLQL-------CPICRAPVRSRVRTFLS 280
>gi|21536421 livin inhibitor of apoptosis isoform alpha [Homo
sapiens]
Length = 298
Score = 43.1 bits (100), Expect = 7e-04
Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 10/55 (18%)
Query: 521 CTICYEHAVDTVIYTCGHMCLCYAC--GLRLKKALHACCPICRRPIKDIIKTYRS 573
C +C + AV V CGH+ +C C GL+L CPICR P++ ++T+ S
Sbjct: 252 CKVCLDRAVSIVFVPCGHL-VCAECAPGLQL-------CPICRAPVRSRVRTFLS 298
>gi|45387949 ring finger and SPRY domain containing 1 [Homo sapiens]
Length = 576
Score = 42.4 bits (98), Expect = 0.001
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 5/49 (10%)
Query: 521 CTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIK 569
C++C + DT + CGH LC C L+L+ CP+CR+ I I+
Sbjct: 527 CSLCCDEVADTQLKPCGHSDLCMDCALQLE-----TCPLCRKEIVSRIR 570
>gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo
sapiens]
Length = 295
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 504 SLPESPVTPGLGQWSDECTICYEHAVDTVIY--TCGHMCLCYACGLRLKKALHACCPICR 561
SLP + + P C IC + I GH+ C+ C +LKK + CP+CR
Sbjct: 233 SLPLNAIEP--------CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKR-NKPCPVCR 283
Query: 562 RPIKDIIKTY 571
+PI+ I+ TY
Sbjct: 284 QPIQMIVLTY 293
>gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo
sapiens]
Length = 442
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 504 SLPESPVTPGLGQWSDECTICYEHAVDTVIY--TCGHMCLCYACGLRLKKALHACCPICR 561
SLP + + P C IC + I GH+ C+ C +LKK + CP+CR
Sbjct: 380 SLPLNAIEP--------CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKR-NKPCPVCR 430
Query: 562 RPIKDIIKTY 571
+PI+ I+ TY
Sbjct: 431 QPIQMIVLTY 440
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,769,088
Number of Sequences: 37866
Number of extensions: 1364116
Number of successful extensions: 5444
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 159
Number of HSP's that attempted gapping in prelim test: 5117
Number of HSP's gapped (non-prelim): 435
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.