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Search of human proteins with 223029500
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo
sapiens]
(856 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo sa... 1712 0.0
gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo sap... 1601 0.0
gi|221219020 NYD-SP11 protein [Homo sapiens] 51 4e-06
gi|56676335 RAP1 interacting factor 1 [Homo sapiens] 49 2e-05
gi|71061468 centromere protein E [Homo sapiens] 49 3e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 49 3e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 49 3e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 49 3e-05
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 49 3e-05
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 49 3e-05
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 49 3e-05
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 49 3e-05
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 49 3e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 4e-05
gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sap... 47 6e-05
gi|55770834 centromere protein F [Homo sapiens] 47 8e-05
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 46 1e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 46 1e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 46 1e-04
gi|148664240 hypothetical protein LOC146556 isoform 1 [Homo sapi... 46 1e-04
gi|7706635 cornulin [Homo sapiens] 45 3e-04
gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens] 45 4e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 45 4e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 44 5e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 44 5e-04
gi|21328446 hormone-sensitive lipase [Homo sapiens] 44 6e-04
gi|148746195 trichohyalin [Homo sapiens] 43 0.001
gi|168693643 decay accelerating factor for complement isoform 2 ... 43 0.001
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 43 0.001
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 42 0.002
>gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo
sapiens]
Length = 856
Score = 1712 bits (4434), Expect = 0.0
Identities = 856/856 (100%), Positives = 856/856 (100%)
Query: 1 MDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKK 60
MDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKK
Sbjct: 1 MDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKK 60
Query: 61 NLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLD 120
NLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLD
Sbjct: 61 NLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLD 120
Query: 121 KLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQR 180
KLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQR
Sbjct: 121 KLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQR 180
Query: 181 LMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIKVKVANTRKQALQEQFDEW 240
LMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIKVKVANTRKQALQEQFDEW
Sbjct: 181 LMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIKVKVANTRKQALQEQFDEW 240
Query: 241 ILDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKD 300
ILDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKD
Sbjct: 241 ILDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKD 300
Query: 301 LKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELF 360
LKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELF
Sbjct: 301 LKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELF 360
Query: 361 YDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANH 420
YDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANH
Sbjct: 361 YDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANH 420
Query: 421 ASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQ 480
ASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQ
Sbjct: 421 ASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQ 480
Query: 481 ELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQ 540
ELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQ
Sbjct: 481 ELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQ 540
Query: 541 GSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPY 600
GSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPY
Sbjct: 541 GSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPY 600
Query: 601 GEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSE 660
GEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSE
Sbjct: 601 GEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSE 660
Query: 661 LQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGKSWSGEFFTCNWKMKYVTFEDEE 720
LQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGKSWSGEFFTCNWKMKYVTFEDEE
Sbjct: 661 LQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGKSWSGEFFTCNWKMKYVTFEDEE 720
Query: 721 QANLIYGNSRFTDLHSIIRNIQSCKEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVS 780
QANLIYGNSRFTDLHSIIRNIQSCKEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVS
Sbjct: 721 QANLIYGNSRFTDLHSIIRNIQSCKEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVS 780
Query: 781 ETLTSFFKEGYVETEQEKMNALEQVSLCRQAGVQWRNCSSLQPPTPGLKRSSHHRLLSNW 840
ETLTSFFKEGYVETEQEKMNALEQVSLCRQAGVQWRNCSSLQPPTPGLKRSSHHRLLSNW
Sbjct: 781 ETLTSFFKEGYVETEQEKMNALEQVSLCRQAGVQWRNCSSLQPPTPGLKRSSHHRLLSNW 840
Query: 841 DYRERRKFFPLETKFP 856
DYRERRKFFPLETKFP
Sbjct: 841 DYRERRKFFPLETKFP 856
>gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo
sapiens]
Length = 1503
Score = 1601 bits (4146), Expect = 0.0
Identities = 805/806 (99%), Positives = 805/806 (99%)
Query: 1 MDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKK 60
MDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKK
Sbjct: 57 MDEIKSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKK 116
Query: 61 NLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLD 120
NLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLD
Sbjct: 117 NLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYLLD 176
Query: 121 KLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQR 180
KLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQR
Sbjct: 177 KLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSGYQR 236
Query: 181 LMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIKVKVANTRKQALQEQFDEW 240
LMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIKVKVANTRKQALQEQFDEW
Sbjct: 237 LMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIKVKVANTRKQALQEQFDEW 296
Query: 241 ILDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKD 300
ILDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKD
Sbjct: 297 ILDPKGMIPKSVIQNVLQEFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKD 356
Query: 301 LKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELF 360
LKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELF
Sbjct: 357 LKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELF 416
Query: 361 YDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANH 420
YDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANH
Sbjct: 417 YDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANH 476
Query: 421 ASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQ 480
ASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQ
Sbjct: 477 ASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQ 536
Query: 481 ELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQ 540
ELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQ
Sbjct: 537 ELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQ 596
Query: 541 GSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPY 600
GSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPY
Sbjct: 597 GSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPY 656
Query: 601 GEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSE 660
GEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSE
Sbjct: 657 GEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSE 716
Query: 661 LQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGKSWSGEFFTCNWKMKYVTFEDEE 720
LQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGKSWSGEFFTCNWKMKYVTFEDEE
Sbjct: 717 LQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGKSWSGEFFTCNWKMKYVTFEDEE 776
Query: 721 QANLIYGNSRFTDLHSIIRNIQSCKEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVS 780
QANLIYGNSRFTDLHSIIRNIQSCKEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVS
Sbjct: 777 QANLIYGNSRFTDLHSIIRNIQSCKEVKGRTAFNGVSFNLLQFVQLLETFVGEDAPLSVS 836
Query: 781 ETLTSFFKEGYVETEQEKMNALEQVS 806
ETLTSFFKEGYVETEQEKMNALEQ S
Sbjct: 837 ETLTSFFKEGYVETEQEKMNALEQFS 862
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 51.2 bits (121), Expect = 4e-06
Identities = 136/700 (19%), Positives = 280/700 (40%), Gaps = 92/700 (13%)
Query: 1 MDEI--KSQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTW 58
M+E+ K +ELN E + + K E +A ++ L E E K E
Sbjct: 1725 MEELSWKEEELNQEEGKLVEE---KKKLAEEEEALAWQREK-----LSEEETKLAQE--- 1773
Query: 59 KKNLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWFNTDSMTLNNTAYL 118
++ L + E AQ ++ ++E L ++ E+ EKK+ + W N+ N L
Sbjct: 1774 EELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMIL 1833
Query: 119 LDKLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLGEYLIRNNPNYIKDPGMSG- 177
K L Q +K + + + + Y E L + ++ G
Sbjct: 1834 YQK----------KNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGM 1883
Query: 178 YQRLMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIKVKVANTR-KQALQEQ 236
+ +++ +V E L +T+ + K+ E K+ + +S+ K + K+A + K AL++
Sbjct: 1884 FNKILAQVEEKL-TQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKA 1942
Query: 237 FDEWILDPKGMIPKSVIQNVLQ-EFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYIS 295
+ +G + + + L E + + K+ + ++ P ++ +
Sbjct: 1943 MVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVE 2002
Query: 296 SHIKDLKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLA 355
+ + K + E++L H + I A M A+ L G+ F+ QR LA
Sbjct: 2003 QELFERKLSLEEKILLH--------EDRILA-MEESEIAKGKLEFTRGQRIFVQGQRKLA 2053
Query: 356 LL--ELFYDHSS---------QMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEG 404
+L S ++L++L + R + EEI +T++ ++ ++
Sbjct: 2054 KASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKM------KRALFVK 2107
Query: 405 FDKVLLEMNTL-LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQ 463
++ +E + L + S+ +S+L + D+ KL ++ + + +R + E +
Sbjct: 2108 ERRLSIEQSKLDIKEWDFSEKRSEL--TKDEKKLARKQRKLAN----KMRRMINKE---E 2158
Query: 464 RISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQH 523
+++ EE + +K E+ ++ E G E + L + R+ +
Sbjct: 2159 KMTEEESKLARK---HSEVILDDEEEGGIEEEEVIP------FLKRRWRKRKEAKRGDKP 2209
Query: 524 KGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSL 583
K Q S ES+ ++ ++ES++ ++ + E+ E+ +
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE-------REEEEV 2262
Query: 584 RESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQE 643
RE EE ++ E+G ++ EE+E + +K+ + + E + E E+ + E
Sbjct: 2263 REE--EEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK----EEVFEEKEEI-MSE 2315
Query: 644 KRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQ 683
+ + + EEE S L+EEV D E KKE Q
Sbjct: 2316 EETESLSDEEEEEESCSLEEEV------DREKEILKKEKQ 2349
>gi|56676335 RAP1 interacting factor 1 [Homo sapiens]
Length = 2472
Score = 49.3 bits (116), Expect = 2e-05
Identities = 65/288 (22%), Positives = 125/288 (43%), Gaps = 33/288 (11%)
Query: 415 LLSANHASKTQSKLLESPDQPKL--NEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQ 472
++SA+ S++ +P+Q L + +R S + E Q + Q +R EE+
Sbjct: 1392 VISADQMVNEDSQVQITPNQKTLRRSSRRRSEVVESTTESQDKENSHQKKERRKEEEKPL 1451
Query: 473 GKKPT--AEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQ 530
K P + L + +I T E+ +E+GS+ T ET + TEQ + K E
Sbjct: 1452 QKSPLHIKDDVLPKQKLIAEQTLQENLIEKGSNLHEKTLGETSANAETEQNKKKADPE-- 1509
Query: 531 GPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEE 590
++ +G + + ++ S + + + R++ A QG +S+ E S +E
Sbjct: 1510 -----NIKSEGDGTQDIVDKSSEK-LVRGRTRYQTRRASQG--LLSSIENSESDSSEAKE 1561
Query: 591 PYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQT 650
+ ++ + S E DI Q +++ ++K E I +E + ++ T
Sbjct: 1562 EGSRKKRSGKWKNKSNESVDI----QDQEEKVVKQ----ECIKAE------NQSHDYKAT 1607
Query: 651 YEEEIFLSS---ELQEEVPTLSRKDHFPETTKKEVQKDKP--CEPKSQ 693
EE++ + S E Q+E T+ +D + +V D P CE K++
Sbjct: 1608 SEEDVSIKSPICEKQDESNTVICQDSTVTSDLLQVPDDLPNVCEEKNE 1655
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 48.5 bits (114), Expect = 3e-05
Identities = 106/528 (20%), Positives = 216/528 (40%), Gaps = 47/528 (8%)
Query: 199 NRVSKMKENVKQNRKQRESIDKIKVKVANTRKQALQEQFDEWILDPKGMIPKSVIQNVLQ 258
N + ++KE ++ +++++ K + +Q L+E + + K + + +Q LQ
Sbjct: 887 NEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEV--KTLTQEKDDLKQ--LQESLQ 942
Query: 259 EFFQNPDFKLGSHCKQLDITDSTEPRLNKMEFTEYISSHIKDLKSEMFEELLKHL----- 313
+ K H D+ E N +E + I LKS++ EE+ ++L
Sbjct: 943 --IERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEEN 1000
Query: 314 -CHSADEFRE-VIKADMRRQMFAE--LFLHCDHGKVGFLDRQRTLALLELFYDHSSQMLR 369
+ DEF++ ++ D ++ + A+ L D +++QR + L + QML
Sbjct: 1001 TGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLE 1060
Query: 370 SLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLL-SANHASKTQSKL 428
S++ Q E I +T ++NQ+ + D++ + + NHA K + +L
Sbjct: 1061 SVIAEKEQLKTDLKENIEMT-----IENQEELRLLGDELKKQQEIVAQEKNHAIKKEGEL 1115
Query: 429 LESPDQPKLNEQRTSTPSPNPPEQQR---GVTAEQGPQRISIEEQQQGKKPTAEQELYIE 485
+ D+ E++ S E+Q+ V E + I E + K +EL +E
Sbjct: 1116 SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175
Query: 486 SV----IEPGTHTESTLEQGSS----RRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSV 537
+ +E E+ S R++L +E + TE+ +G I R +
Sbjct: 1176 HMETERLELAQKLNENYEEVKSITKERKVL--KELQKSFETERDHLRGYI-----REIEA 1228
Query: 538 SEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEE---PYQK 594
+ + E +E D + SV+E+ ++ ++ + + EE +++
Sbjct: 1229 TGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEE 1288
Query: 595 SEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQ----T 650
E P + +SE QE + + S K + I E + + + + S E+ T
Sbjct: 1289 QELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLT 1348
Query: 651 YEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEGK 698
E + + + EV K+H ET K +Q+ + + +S ++ K
Sbjct: 1349 KERDNLKTIKEALEVKHDQLKEHIRETLAK-IQESQSKQEQSLNMKEK 1395
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 32/245 (13%)
Query: 453 QRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEP----------------GTHTES 496
Q+ + AE+ ++++++Q + T +QE +SV++ ++
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQE---QSVLDQLRGEAEAARRAAEEAEEARVQA 2100
Query: 497 TLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRE- 555
E SRR + E E ++S EQ Q + + + +EQ ++R + AEQ + R+
Sbjct: 2101 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160
Query: 556 --SIAEQDRHKGSVAEQGSRRMSAAEQ--GSLRESVIEEPYQKS-EQGPYGEIISEEQED 610
+ AE ++HK AEQ R+ + EQ +LR + E +QK+ + +E E
Sbjct: 2161 QAADAEMEKHK-KFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2219
Query: 611 IGSTSQSRKD------SILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
SQ ++ + + +K I +E + L++K + ++ +EE ++ EE
Sbjct: 2220 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2279
Query: 665 VPTLS 669
LS
Sbjct: 2280 AARLS 2284
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/294 (20%), Positives = 116/294 (39%), Gaps = 53/294 (18%)
Query: 413 NTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPE--QQRGVTAEQGPQRISIEEQ 470
N L TQ L E ++ K + + S E + R + E Q+ ++ E+
Sbjct: 2251 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2310
Query: 471 QQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQ-HKGSIEG 529
+K A QE + L Q +RRL ++E + E+ Q + ++E
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 530 QGPRRVSVSEQGSSRESVAEQGSRRESIAEQDR--------------HKGSVAEQGS--- 572
+ R++ +S + + + SR ++ AE+D H+ +A Q
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2430
Query: 573 -------RRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQ--------- 616
R+ S + LRE++ E +K + +++ + E++ + Q
Sbjct: 2431 VQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA 2490
Query: 617 ------SRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
S KDS+L+ ++ E QEK EQ +++E+ + +L+EE
Sbjct: 2491 LQQSFLSEKDSLLQRERFIE-----------QEKAKLEQLFQDEVAKAQQLREE 2533
Score = 39.7 bits (91), Expect = 0.012
Identities = 56/273 (20%), Positives = 108/273 (39%), Gaps = 49/273 (17%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
L AN A + + + E Q L + E+Q+ + +R EEQ ++
Sbjct: 1636 LKANEALRLRLQAEEVAQQKSLAQAEA--------EKQKEEAEREARRRGKAEEQAVRQR 1687
Query: 476 PTAEQELYIESVIEPGT------------HTESTLEQGSSRRLLTEQETHR--ESTTEQG 521
AEQEL + + GT + EQG +R L E+E R
Sbjct: 1688 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1747
Query: 522 QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKG------SVAEQGSRRM 575
Q + +E + + + E + ++ AE+ SR S + R + +AE+ +R
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807
Query: 576 SAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSE 635
+ AE+ + + EE + ++ +++E+ IG ++ + ++
Sbjct: 1808 ALAEEAKRQRQLAEEDAAR-QRAEAERVLAEKLAAIGEATRLKTEA-------------- 1852
Query: 636 YIEVPLQEKRSWEQTY----EEEIFLSSELQEE 664
E+ L+EK + + E+E F L+E+
Sbjct: 1853 --EIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1883
Score = 33.5 bits (75), Expect = 0.86
Identities = 52/296 (17%), Positives = 130/296 (43%), Gaps = 20/296 (6%)
Query: 406 DKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRI 465
++VL E + KT++++ + + + +R + + Q+R + + +
Sbjct: 1832 ERVLAEKLAAIGEATRLKTEAEI--ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA 1889
Query: 466 SIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQH-K 524
IEE+ + ++ EL + + E TL Q RR + E+ +++ E+ K
Sbjct: 1890 DIEERLAQLRKASDSELERQKGL-----VEDTLRQ---RRQVEEEILALKASFEKAAAGK 1941
Query: 525 GSIEGQ-GPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSL 583
+E + G R + + S+E + +R+ +A ++ + AE+ ++ AAE+ +
Sbjct: 1942 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2001
Query: 584 RE--SVIEEPYQ-KSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVP 640
R+ + +EE + K++ + +++ Q +++ K + E + ++
Sbjct: 2002 RQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ-- 2059
Query: 641 LQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
Q+++ +QT ++E + +L+ E R E + VQ ++ +++E
Sbjct: 2060 -QKEQELQQTLQQEQSVLDQLRGEAEAARRAAE--EAEEARVQAEREAAQSRRQVE 2112
Score = 32.7 bits (73), Expect = 1.5
Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 14/191 (7%)
Query: 452 QQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLE--QGSSRRLLTE 509
QQ AE+ + I+ E+++ K + L ++S E L+ Q + L+E
Sbjct: 2439 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2498
Query: 510 QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHK-GSVA 568
+++ + Q K +E V+ ++Q + E+ R++ EQ+R + +
Sbjct: 2499 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ------LREEQQRQQQQMEQERQRLVASM 2552
Query: 569 EQGSRRMSAAEQGSLRESVIEEPYQKSEQ--GPYGEIISEEQEDIGSTSQSRKDSILKST 626
E+ RR AE+G R+ +E Q+ EQ E+++EE + + Q ++ +
Sbjct: 2553 EEARRRQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2609
Query: 627 KYGEPITSEYI 637
+ E +T+ +
Sbjct: 2610 AHSEEVTASQV 2620
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 32/245 (13%)
Query: 453 QRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEP----------------GTHTES 496
Q+ + AE+ ++++++Q + T +QE +SV++ ++
Sbjct: 2048 QKRLQAEEKAHAFAVQQKEQELQQTLQQE---QSVLDQLRGEAEAARRAAEEAEEARVQA 2104
Query: 497 TLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRE- 555
E SRR + E E ++S EQ Q + + + +EQ ++R + AEQ + R+
Sbjct: 2105 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2164
Query: 556 --SIAEQDRHKGSVAEQGSRRMSAAEQ--GSLRESVIEEPYQKS-EQGPYGEIISEEQED 610
+ AE ++HK AEQ R+ + EQ +LR + E +QK+ + +E E
Sbjct: 2165 QAADAEMEKHK-KFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2223
Query: 611 IGSTSQSRKD------SILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
SQ ++ + + +K I +E + L++K + ++ +EE ++ EE
Sbjct: 2224 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2283
Query: 665 VPTLS 669
LS
Sbjct: 2284 AARLS 2288
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/294 (20%), Positives = 116/294 (39%), Gaps = 53/294 (18%)
Query: 413 NTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPE--QQRGVTAEQGPQRISIEEQ 470
N L TQ L E ++ K + + S E + R + E Q+ ++ E+
Sbjct: 2255 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2314
Query: 471 QQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQ-HKGSIEG 529
+K A QE + L Q +RRL ++E + E+ Q + ++E
Sbjct: 2315 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2374
Query: 530 QGPRRVSVSEQGSSRESVAEQGSRRESIAEQDR--------------HKGSVAEQGS--- 572
+ R++ +S + + + SR ++ AE+D H+ +A Q
Sbjct: 2375 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2434
Query: 573 -------RRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQ--------- 616
R+ S + LRE++ E +K + +++ + E++ + Q
Sbjct: 2435 VQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA 2494
Query: 617 ------SRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
S KDS+L+ ++ E QEK EQ +++E+ + +L+EE
Sbjct: 2495 LQQSFLSEKDSLLQRERFIE-----------QEKAKLEQLFQDEVAKAQQLREE 2537
Score = 39.7 bits (91), Expect = 0.012
Identities = 56/273 (20%), Positives = 108/273 (39%), Gaps = 49/273 (17%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
L AN A + + + E Q L + E+Q+ + +R EEQ ++
Sbjct: 1640 LKANEALRLRLQAEEVAQQKSLAQAEA--------EKQKEEAEREARRRGKAEEQAVRQR 1691
Query: 476 PTAEQELYIESVIEPGT------------HTESTLEQGSSRRLLTEQETHR--ESTTEQG 521
AEQEL + + GT + EQG +R L E+E R
Sbjct: 1692 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1751
Query: 522 QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKG------SVAEQGSRRM 575
Q + +E + + + E + ++ AE+ SR S + R + +AE+ +R
Sbjct: 1752 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1811
Query: 576 SAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSE 635
+ AE+ + + EE + ++ +++E+ IG ++ + ++
Sbjct: 1812 ALAEEAKRQRQLAEEDAAR-QRAEAERVLAEKLAAIGEATRLKTEA-------------- 1856
Query: 636 YIEVPLQEKRSWEQTY----EEEIFLSSELQEE 664
E+ L+EK + + E+E F L+E+
Sbjct: 1857 --EIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1887
Score = 33.5 bits (75), Expect = 0.86
Identities = 52/296 (17%), Positives = 130/296 (43%), Gaps = 20/296 (6%)
Query: 406 DKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRI 465
++VL E + KT++++ + + + +R + + Q+R + + +
Sbjct: 1836 ERVLAEKLAAIGEATRLKTEAEI--ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA 1893
Query: 466 SIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQH-K 524
IEE+ + ++ EL + + E TL Q RR + E+ +++ E+ K
Sbjct: 1894 DIEERLAQLRKASDSELERQKGL-----VEDTLRQ---RRQVEEEILALKASFEKAAAGK 1945
Query: 525 GSIEGQ-GPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSL 583
+E + G R + + S+E + +R+ +A ++ + AE+ ++ AAE+ +
Sbjct: 1946 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2005
Query: 584 RE--SVIEEPYQ-KSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVP 640
R+ + +EE + K++ + +++ Q +++ K + E + ++
Sbjct: 2006 RQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ-- 2063
Query: 641 LQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
Q+++ +QT ++E + +L+ E R E + VQ ++ +++E
Sbjct: 2064 -QKEQELQQTLQQEQSVLDQLRGEAEAARRAAE--EAEEARVQAEREAAQSRRQVE 2116
Score = 32.7 bits (73), Expect = 1.5
Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 14/191 (7%)
Query: 452 QQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLE--QGSSRRLLTE 509
QQ AE+ + I+ E+++ K + L ++S E L+ Q + L+E
Sbjct: 2443 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2502
Query: 510 QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHK-GSVA 568
+++ + Q K +E V+ ++Q + E+ R++ EQ+R + +
Sbjct: 2503 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ------LREEQQRQQQQMEQERQRLVASM 2556
Query: 569 EQGSRRMSAAEQGSLRESVIEEPYQKSEQ--GPYGEIISEEQEDIGSTSQSRKDSILKST 626
E+ RR AE+G R+ +E Q+ EQ E+++EE + + Q ++ +
Sbjct: 2557 EEARRRQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2613
Query: 627 KYGEPITSEYI 637
+ E +T+ +
Sbjct: 2614 AHSEEVTASQV 2624
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 32/245 (13%)
Query: 453 QRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEP----------------GTHTES 496
Q+ + AE+ ++++++Q + T +QE +SV++ ++
Sbjct: 2044 QKRLQAEEKAHAFAVQQKEQELQQTLQQE---QSVLDQLRGEAEAARRAAEEAEEARVQA 2100
Query: 497 TLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRE- 555
E SRR + E E ++S EQ Q + + + +EQ ++R + AEQ + R+
Sbjct: 2101 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2160
Query: 556 --SIAEQDRHKGSVAEQGSRRMSAAEQ--GSLRESVIEEPYQKS-EQGPYGEIISEEQED 610
+ AE ++HK AEQ R+ + EQ +LR + E +QK+ + +E E
Sbjct: 2161 QAADAEMEKHK-KFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2219
Query: 611 IGSTSQSRKD------SILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
SQ ++ + + +K I +E + L++K + ++ +EE ++ EE
Sbjct: 2220 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2279
Query: 665 VPTLS 669
LS
Sbjct: 2280 AARLS 2284
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/294 (20%), Positives = 116/294 (39%), Gaps = 53/294 (18%)
Query: 413 NTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPE--QQRGVTAEQGPQRISIEEQ 470
N L TQ L E ++ K + + S E + R + E Q+ ++ E+
Sbjct: 2251 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2310
Query: 471 QQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQ-HKGSIEG 529
+K A QE + L Q +RRL ++E + E+ Q + ++E
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 530 QGPRRVSVSEQGSSRESVAEQGSRRESIAEQDR--------------HKGSVAEQGS--- 572
+ R++ +S + + + SR ++ AE+D H+ +A Q
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2430
Query: 573 -------RRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQ--------- 616
R+ S + LRE++ E +K + +++ + E++ + Q
Sbjct: 2431 VQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA 2490
Query: 617 ------SRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
S KDS+L+ ++ E QEK EQ +++E+ + +L+EE
Sbjct: 2491 LQQSFLSEKDSLLQRERFIE-----------QEKAKLEQLFQDEVAKAQQLREE 2533
Score = 39.7 bits (91), Expect = 0.012
Identities = 56/273 (20%), Positives = 108/273 (39%), Gaps = 49/273 (17%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
L AN A + + + E Q L + E+Q+ + +R EEQ ++
Sbjct: 1636 LKANEALRLRLQAEEVAQQKSLAQAEA--------EKQKEEAEREARRRGKAEEQAVRQR 1687
Query: 476 PTAEQELYIESVIEPGT------------HTESTLEQGSSRRLLTEQETHR--ESTTEQG 521
AEQEL + + GT + EQG +R L E+E R
Sbjct: 1688 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1747
Query: 522 QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKG------SVAEQGSRRM 575
Q + +E + + + E + ++ AE+ SR S + R + +AE+ +R
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807
Query: 576 SAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSE 635
+ AE+ + + EE + ++ +++E+ IG ++ + ++
Sbjct: 1808 ALAEEAKRQRQLAEEDAAR-QRAEAERVLAEKLAAIGEATRLKTEA-------------- 1852
Query: 636 YIEVPLQEKRSWEQTY----EEEIFLSSELQEE 664
E+ L+EK + + E+E F L+E+
Sbjct: 1853 --EIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1883
Score = 33.5 bits (75), Expect = 0.86
Identities = 52/296 (17%), Positives = 130/296 (43%), Gaps = 20/296 (6%)
Query: 406 DKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRI 465
++VL E + KT++++ + + + +R + + Q+R + + +
Sbjct: 1832 ERVLAEKLAAIGEATRLKTEAEI--ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA 1889
Query: 466 SIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQH-K 524
IEE+ + ++ EL + + E TL Q RR + E+ +++ E+ K
Sbjct: 1890 DIEERLAQLRKASDSELERQKGL-----VEDTLRQ---RRQVEEEILALKASFEKAAAGK 1941
Query: 525 GSIEGQ-GPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSL 583
+E + G R + + S+E + +R+ +A ++ + AE+ ++ AAE+ +
Sbjct: 1942 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2001
Query: 584 RE--SVIEEPYQ-KSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVP 640
R+ + +EE + K++ + +++ Q +++ K + E + ++
Sbjct: 2002 RQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ-- 2059
Query: 641 LQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
Q+++ +QT ++E + +L+ E R E + VQ ++ +++E
Sbjct: 2060 -QKEQELQQTLQQEQSVLDQLRGEAEAARRAAE--EAEEARVQAEREAAQSRRQVE 2112
Score = 32.7 bits (73), Expect = 1.5
Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 14/191 (7%)
Query: 452 QQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLE--QGSSRRLLTE 509
QQ AE+ + I+ E+++ K + L ++S E L+ Q + L+E
Sbjct: 2439 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2498
Query: 510 QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHK-GSVA 568
+++ + Q K +E V+ ++Q + E+ R++ EQ+R + +
Sbjct: 2499 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ------LREEQQRQQQQMEQERQRLVASM 2552
Query: 569 EQGSRRMSAAEQGSLRESVIEEPYQKSEQ--GPYGEIISEEQEDIGSTSQSRKDSILKST 626
E+ RR AE+G R+ +E Q+ EQ E+++EE + + Q ++ +
Sbjct: 2553 EEARRRQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2609
Query: 627 KYGEPITSEYI 637
+ E +T+ +
Sbjct: 2610 AHSEEVTASQV 2620
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 32/245 (13%)
Query: 453 QRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEP----------------GTHTES 496
Q+ + AE+ ++++++Q + T +QE +SV++ ++
Sbjct: 2012 QKRLQAEEKAHAFAVQQKEQELQQTLQQE---QSVLDQLRGEAEAARRAAEEAEEARVQA 2068
Query: 497 TLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRE- 555
E SRR + E E ++S EQ Q + + + +EQ ++R + AEQ + R+
Sbjct: 2069 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2128
Query: 556 --SIAEQDRHKGSVAEQGSRRMSAAEQ--GSLRESVIEEPYQKS-EQGPYGEIISEEQED 610
+ AE ++HK AEQ R+ + EQ +LR + E +QK+ + +E E
Sbjct: 2129 QAADAEMEKHK-KFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2187
Query: 611 IGSTSQSRKD------SILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
SQ ++ + + +K I +E + L++K + ++ +EE ++ EE
Sbjct: 2188 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2247
Query: 665 VPTLS 669
LS
Sbjct: 2248 AARLS 2252
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/294 (20%), Positives = 116/294 (39%), Gaps = 53/294 (18%)
Query: 413 NTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPE--QQRGVTAEQGPQRISIEEQ 470
N L TQ L E ++ K + + S E + R + E Q+ ++ E+
Sbjct: 2219 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2278
Query: 471 QQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQ-HKGSIEG 529
+K A QE + L Q +RRL ++E + E+ Q + ++E
Sbjct: 2279 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2338
Query: 530 QGPRRVSVSEQGSSRESVAEQGSRRESIAEQDR--------------HKGSVAEQGS--- 572
+ R++ +S + + + SR ++ AE+D H+ +A Q
Sbjct: 2339 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2398
Query: 573 -------RRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQ--------- 616
R+ S + LRE++ E +K + +++ + E++ + Q
Sbjct: 2399 VQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA 2458
Query: 617 ------SRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
S KDS+L+ ++ E QEK EQ +++E+ + +L+EE
Sbjct: 2459 LQQSFLSEKDSLLQRERFIE-----------QEKAKLEQLFQDEVAKAQQLREE 2501
Score = 39.7 bits (91), Expect = 0.012
Identities = 56/273 (20%), Positives = 108/273 (39%), Gaps = 49/273 (17%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
L AN A + + + E Q L + E+Q+ + +R EEQ ++
Sbjct: 1604 LKANEALRLRLQAEEVAQQKSLAQAEA--------EKQKEEAEREARRRGKAEEQAVRQR 1655
Query: 476 PTAEQELYIESVIEPGT------------HTESTLEQGSSRRLLTEQETHR--ESTTEQG 521
AEQEL + + GT + EQG +R L E+E R
Sbjct: 1656 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1715
Query: 522 QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKG------SVAEQGSRRM 575
Q + +E + + + E + ++ AE+ SR S + R + +AE+ +R
Sbjct: 1716 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1775
Query: 576 SAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSE 635
+ AE+ + + EE + ++ +++E+ IG ++ + ++
Sbjct: 1776 ALAEEAKRQRQLAEEDAAR-QRAEAERVLAEKLAAIGEATRLKTEA-------------- 1820
Query: 636 YIEVPLQEKRSWEQTY----EEEIFLSSELQEE 664
E+ L+EK + + E+E F L+E+
Sbjct: 1821 --EIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1851
Score = 33.5 bits (75), Expect = 0.86
Identities = 52/296 (17%), Positives = 130/296 (43%), Gaps = 20/296 (6%)
Query: 406 DKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRI 465
++VL E + KT++++ + + + +R + + Q+R + + +
Sbjct: 1800 ERVLAEKLAAIGEATRLKTEAEI--ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA 1857
Query: 466 SIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQH-K 524
IEE+ + ++ EL + + E TL Q RR + E+ +++ E+ K
Sbjct: 1858 DIEERLAQLRKASDSELERQKGL-----VEDTLRQ---RRQVEEEILALKASFEKAAAGK 1909
Query: 525 GSIEGQ-GPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSL 583
+E + G R + + S+E + +R+ +A ++ + AE+ ++ AAE+ +
Sbjct: 1910 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAA 1969
Query: 584 RE--SVIEEPYQ-KSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVP 640
R+ + +EE + K++ + +++ Q +++ K + E + ++
Sbjct: 1970 RQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ-- 2027
Query: 641 LQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
Q+++ +QT ++E + +L+ E R E + VQ ++ +++E
Sbjct: 2028 -QKEQELQQTLQQEQSVLDQLRGEAEAARRAAE--EAEEARVQAEREAAQSRRQVE 2080
Score = 32.7 bits (73), Expect = 1.5
Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 14/191 (7%)
Query: 452 QQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLE--QGSSRRLLTE 509
QQ AE+ + I+ E+++ K + L ++S E L+ Q + L+E
Sbjct: 2407 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2466
Query: 510 QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHK-GSVA 568
+++ + Q K +E V+ ++Q + E+ R++ EQ+R + +
Sbjct: 2467 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ------LREEQQRQQQQMEQERQRLVASM 2520
Query: 569 EQGSRRMSAAEQGSLRESVIEEPYQKSEQ--GPYGEIISEEQEDIGSTSQSRKDSILKST 626
E+ RR AE+G R+ +E Q+ EQ E+++EE + + Q ++ +
Sbjct: 2521 EEARRRQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2577
Query: 627 KYGEPITSEYI 637
+ E +T+ +
Sbjct: 2578 AHSEEVTASQV 2588
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 32/245 (13%)
Query: 453 QRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEP----------------GTHTES 496
Q+ + AE+ ++++++Q + T +QE +SV++ ++
Sbjct: 2181 QKRLQAEEKAHAFAVQQKEQELQQTLQQE---QSVLDQLRGEAEAARRAAEEAEEARVQA 2237
Query: 497 TLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRE- 555
E SRR + E E ++S EQ Q + + + +EQ ++R + AEQ + R+
Sbjct: 2238 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2297
Query: 556 --SIAEQDRHKGSVAEQGSRRMSAAEQ--GSLRESVIEEPYQKS-EQGPYGEIISEEQED 610
+ AE ++HK AEQ R+ + EQ +LR + E +QK+ + +E E
Sbjct: 2298 QAADAEMEKHK-KFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2356
Query: 611 IGSTSQSRKD------SILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
SQ ++ + + +K I +E + L++K + ++ +EE ++ EE
Sbjct: 2357 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2416
Query: 665 VPTLS 669
LS
Sbjct: 2417 AARLS 2421
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/294 (20%), Positives = 116/294 (39%), Gaps = 53/294 (18%)
Query: 413 NTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPE--QQRGVTAEQGPQRISIEEQ 470
N L TQ L E ++ K + + S E + R + E Q+ ++ E+
Sbjct: 2388 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2447
Query: 471 QQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQ-HKGSIEG 529
+K A QE + L Q +RRL ++E + E+ Q + ++E
Sbjct: 2448 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2507
Query: 530 QGPRRVSVSEQGSSRESVAEQGSRRESIAEQDR--------------HKGSVAEQGS--- 572
+ R++ +S + + + SR ++ AE+D H+ +A Q
Sbjct: 2508 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2567
Query: 573 -------RRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQ--------- 616
R+ S + LRE++ E +K + +++ + E++ + Q
Sbjct: 2568 VQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA 2627
Query: 617 ------SRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
S KDS+L+ ++ E QEK EQ +++E+ + +L+EE
Sbjct: 2628 LQQSFLSEKDSLLQRERFIE-----------QEKAKLEQLFQDEVAKAQQLREE 2670
Score = 39.7 bits (91), Expect = 0.012
Identities = 56/273 (20%), Positives = 108/273 (39%), Gaps = 49/273 (17%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
L AN A + + + E Q L + E+Q+ + +R EEQ ++
Sbjct: 1773 LKANEALRLRLQAEEVAQQKSLAQAEA--------EKQKEEAEREARRRGKAEEQAVRQR 1824
Query: 476 PTAEQELYIESVIEPGT------------HTESTLEQGSSRRLLTEQETHR--ESTTEQG 521
AEQEL + + GT + EQG +R L E+E R
Sbjct: 1825 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1884
Query: 522 QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKG------SVAEQGSRRM 575
Q + +E + + + E + ++ AE+ SR S + R + +AE+ +R
Sbjct: 1885 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1944
Query: 576 SAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSE 635
+ AE+ + + EE + ++ +++E+ IG ++ + ++
Sbjct: 1945 ALAEEAKRQRQLAEEDAAR-QRAEAERVLAEKLAAIGEATRLKTEA-------------- 1989
Query: 636 YIEVPLQEKRSWEQTY----EEEIFLSSELQEE 664
E+ L+EK + + E+E F L+E+
Sbjct: 1990 --EIALKEKEAENERLRRLAEDEAFQRRRLEEQ 2020
Score = 33.5 bits (75), Expect = 0.86
Identities = 52/296 (17%), Positives = 130/296 (43%), Gaps = 20/296 (6%)
Query: 406 DKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRI 465
++VL E + KT++++ + + + +R + + Q+R + + +
Sbjct: 1969 ERVLAEKLAAIGEATRLKTEAEI--ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA 2026
Query: 466 SIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQH-K 524
IEE+ + ++ EL + + E TL Q RR + E+ +++ E+ K
Sbjct: 2027 DIEERLAQLRKASDSELERQKGL-----VEDTLRQ---RRQVEEEILALKASFEKAAAGK 2078
Query: 525 GSIEGQ-GPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSL 583
+E + G R + + S+E + +R+ +A ++ + AE+ ++ AAE+ +
Sbjct: 2079 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2138
Query: 584 RE--SVIEEPYQ-KSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVP 640
R+ + +EE + K++ + +++ Q +++ K + E + ++
Sbjct: 2139 RQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ-- 2196
Query: 641 LQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
Q+++ +QT ++E + +L+ E R E + VQ ++ +++E
Sbjct: 2197 -QKEQELQQTLQQEQSVLDQLRGEAEAARRAAE--EAEEARVQAEREAAQSRRQVE 2249
Score = 32.7 bits (73), Expect = 1.5
Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 14/191 (7%)
Query: 452 QQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLE--QGSSRRLLTE 509
QQ AE+ + I+ E+++ K + L ++S E L+ Q + L+E
Sbjct: 2576 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2635
Query: 510 QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHK-GSVA 568
+++ + Q K +E V+ ++Q + E+ R++ EQ+R + +
Sbjct: 2636 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ------LREEQQRQQQQMEQERQRLVASM 2689
Query: 569 EQGSRRMSAAEQGSLRESVIEEPYQKSEQ--GPYGEIISEEQEDIGSTSQSRKDSILKST 626
E+ RR AE+G R+ +E Q+ EQ E+++EE + + Q ++ +
Sbjct: 2690 EEARRRQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2746
Query: 627 KYGEPITSEYI 637
+ E +T+ +
Sbjct: 2747 AHSEEVTASQV 2757
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 32/245 (13%)
Query: 453 QRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEP----------------GTHTES 496
Q+ + AE+ ++++++Q + T +QE +SV++ ++
Sbjct: 2022 QKRLQAEEKAHAFAVQQKEQELQQTLQQE---QSVLDQLRGEAEAARRAAEEAEEARVQA 2078
Query: 497 TLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRE- 555
E SRR + E E ++S EQ Q + + + +EQ ++R + AEQ + R+
Sbjct: 2079 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2138
Query: 556 --SIAEQDRHKGSVAEQGSRRMSAAEQ--GSLRESVIEEPYQKS-EQGPYGEIISEEQED 610
+ AE ++HK AEQ R+ + EQ +LR + E +QK+ + +E E
Sbjct: 2139 QAADAEMEKHK-KFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2197
Query: 611 IGSTSQSRKD------SILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
SQ ++ + + +K I +E + L++K + ++ +EE ++ EE
Sbjct: 2198 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2257
Query: 665 VPTLS 669
LS
Sbjct: 2258 AARLS 2262
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/294 (20%), Positives = 116/294 (39%), Gaps = 53/294 (18%)
Query: 413 NTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPE--QQRGVTAEQGPQRISIEEQ 470
N L TQ L E ++ K + + S E + R + E Q+ ++ E+
Sbjct: 2229 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2288
Query: 471 QQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQ-HKGSIEG 529
+K A QE + L Q +RRL ++E + E+ Q + ++E
Sbjct: 2289 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2348
Query: 530 QGPRRVSVSEQGSSRESVAEQGSRRESIAEQDR--------------HKGSVAEQGS--- 572
+ R++ +S + + + SR ++ AE+D H+ +A Q
Sbjct: 2349 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2408
Query: 573 -------RRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQ--------- 616
R+ S + LRE++ E +K + +++ + E++ + Q
Sbjct: 2409 VQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA 2468
Query: 617 ------SRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
S KDS+L+ ++ E QEK EQ +++E+ + +L+EE
Sbjct: 2469 LQQSFLSEKDSLLQRERFIE-----------QEKAKLEQLFQDEVAKAQQLREE 2511
Score = 39.7 bits (91), Expect = 0.012
Identities = 56/273 (20%), Positives = 108/273 (39%), Gaps = 49/273 (17%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
L AN A + + + E Q L + E+Q+ + +R EEQ ++
Sbjct: 1614 LKANEALRLRLQAEEVAQQKSLAQAEA--------EKQKEEAEREARRRGKAEEQAVRQR 1665
Query: 476 PTAEQELYIESVIEPGT------------HTESTLEQGSSRRLLTEQETHR--ESTTEQG 521
AEQEL + + GT + EQG +R L E+E R
Sbjct: 1666 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1725
Query: 522 QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKG------SVAEQGSRRM 575
Q + +E + + + E + ++ AE+ SR S + R + +AE+ +R
Sbjct: 1726 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1785
Query: 576 SAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSE 635
+ AE+ + + EE + ++ +++E+ IG ++ + ++
Sbjct: 1786 ALAEEAKRQRQLAEEDAAR-QRAEAERVLAEKLAAIGEATRLKTEA-------------- 1830
Query: 636 YIEVPLQEKRSWEQTY----EEEIFLSSELQEE 664
E+ L+EK + + E+E F L+E+
Sbjct: 1831 --EIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1861
Score = 33.5 bits (75), Expect = 0.86
Identities = 52/296 (17%), Positives = 130/296 (43%), Gaps = 20/296 (6%)
Query: 406 DKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRI 465
++VL E + KT++++ + + + +R + + Q+R + + +
Sbjct: 1810 ERVLAEKLAAIGEATRLKTEAEI--ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA 1867
Query: 466 SIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQH-K 524
IEE+ + ++ EL + + E TL Q RR + E+ +++ E+ K
Sbjct: 1868 DIEERLAQLRKASDSELERQKGL-----VEDTLRQ---RRQVEEEILALKASFEKAAAGK 1919
Query: 525 GSIEGQ-GPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSL 583
+E + G R + + S+E + +R+ +A ++ + AE+ ++ AAE+ +
Sbjct: 1920 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAA 1979
Query: 584 RE--SVIEEPYQ-KSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVP 640
R+ + +EE + K++ + +++ Q +++ K + E + ++
Sbjct: 1980 RQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ-- 2037
Query: 641 LQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
Q+++ +QT ++E + +L+ E R E + VQ ++ +++E
Sbjct: 2038 -QKEQELQQTLQQEQSVLDQLRGEAEAARRAAE--EAEEARVQAEREAAQSRRQVE 2090
Score = 32.7 bits (73), Expect = 1.5
Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 14/191 (7%)
Query: 452 QQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLE--QGSSRRLLTE 509
QQ AE+ + I+ E+++ K + L ++S E L+ Q + L+E
Sbjct: 2417 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2476
Query: 510 QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHK-GSVA 568
+++ + Q K +E V+ ++Q + E+ R++ EQ+R + +
Sbjct: 2477 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ------LREEQQRQQQQMEQERQRLVASM 2530
Query: 569 EQGSRRMSAAEQGSLRESVIEEPYQKSEQ--GPYGEIISEEQEDIGSTSQSRKDSILKST 626
E+ RR AE+G R+ +E Q+ EQ E+++EE + + Q ++ +
Sbjct: 2531 EEARRRQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2587
Query: 627 KYGEPITSEYI 637
+ E +T+ +
Sbjct: 2588 AHSEEVTASQV 2598
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 32/245 (13%)
Query: 453 QRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEP----------------GTHTES 496
Q+ + AE+ ++++++Q + T +QE +SV++ ++
Sbjct: 2030 QKRLQAEEKAHAFAVQQKEQELQQTLQQE---QSVLDQLRGEAEAARRAAEEAEEARVQA 2086
Query: 497 TLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRE- 555
E SRR + E E ++S EQ Q + + + +EQ ++R + AEQ + R+
Sbjct: 2087 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2146
Query: 556 --SIAEQDRHKGSVAEQGSRRMSAAEQ--GSLRESVIEEPYQKS-EQGPYGEIISEEQED 610
+ AE ++HK AEQ R+ + EQ +LR + E +QK+ + +E E
Sbjct: 2147 QAADAEMEKHK-KFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2205
Query: 611 IGSTSQSRKD------SILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
SQ ++ + + +K I +E + L++K + ++ +EE ++ EE
Sbjct: 2206 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2265
Query: 665 VPTLS 669
LS
Sbjct: 2266 AARLS 2270
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/294 (20%), Positives = 116/294 (39%), Gaps = 53/294 (18%)
Query: 413 NTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPE--QQRGVTAEQGPQRISIEEQ 470
N L TQ L E ++ K + + S E + R + E Q+ ++ E+
Sbjct: 2237 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2296
Query: 471 QQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQ-HKGSIEG 529
+K A QE + L Q +RRL ++E + E+ Q + ++E
Sbjct: 2297 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2356
Query: 530 QGPRRVSVSEQGSSRESVAEQGSRRESIAEQDR--------------HKGSVAEQGS--- 572
+ R++ +S + + + SR ++ AE+D H+ +A Q
Sbjct: 2357 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2416
Query: 573 -------RRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQ--------- 616
R+ S + LRE++ E +K + +++ + E++ + Q
Sbjct: 2417 VQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA 2476
Query: 617 ------SRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
S KDS+L+ ++ E QEK EQ +++E+ + +L+EE
Sbjct: 2477 LQQSFLSEKDSLLQRERFIE-----------QEKAKLEQLFQDEVAKAQQLREE 2519
Score = 39.7 bits (91), Expect = 0.012
Identities = 56/273 (20%), Positives = 108/273 (39%), Gaps = 49/273 (17%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
L AN A + + + E Q L + E+Q+ + +R EEQ ++
Sbjct: 1622 LKANEALRLRLQAEEVAQQKSLAQAEA--------EKQKEEAEREARRRGKAEEQAVRQR 1673
Query: 476 PTAEQELYIESVIEPGT------------HTESTLEQGSSRRLLTEQETHR--ESTTEQG 521
AEQEL + + GT + EQG +R L E+E R
Sbjct: 1674 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1733
Query: 522 QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKG------SVAEQGSRRM 575
Q + +E + + + E + ++ AE+ SR S + R + +AE+ +R
Sbjct: 1734 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1793
Query: 576 SAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSE 635
+ AE+ + + EE + ++ +++E+ IG ++ + ++
Sbjct: 1794 ALAEEAKRQRQLAEEDAAR-QRAEAERVLAEKLAAIGEATRLKTEA-------------- 1838
Query: 636 YIEVPLQEKRSWEQTY----EEEIFLSSELQEE 664
E+ L+EK + + E+E F L+E+
Sbjct: 1839 --EIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1869
Score = 33.5 bits (75), Expect = 0.86
Identities = 52/296 (17%), Positives = 130/296 (43%), Gaps = 20/296 (6%)
Query: 406 DKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRI 465
++VL E + KT++++ + + + +R + + Q+R + + +
Sbjct: 1818 ERVLAEKLAAIGEATRLKTEAEI--ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA 1875
Query: 466 SIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQH-K 524
IEE+ + ++ EL + + E TL Q RR + E+ +++ E+ K
Sbjct: 1876 DIEERLAQLRKASDSELERQKGL-----VEDTLRQ---RRQVEEEILALKASFEKAAAGK 1927
Query: 525 GSIEGQ-GPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSL 583
+E + G R + + S+E + +R+ +A ++ + AE+ ++ AAE+ +
Sbjct: 1928 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAA 1987
Query: 584 RE--SVIEEPYQ-KSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVP 640
R+ + +EE + K++ + +++ Q +++ K + E + ++
Sbjct: 1988 RQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ-- 2045
Query: 641 LQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
Q+++ +QT ++E + +L+ E R E + VQ ++ +++E
Sbjct: 2046 -QKEQELQQTLQQEQSVLDQLRGEAEAARRAAE--EAEEARVQAEREAAQSRRQVE 2098
Score = 32.7 bits (73), Expect = 1.5
Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 14/191 (7%)
Query: 452 QQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLE--QGSSRRLLTE 509
QQ AE+ + I+ E+++ K + L ++S E L+ Q + L+E
Sbjct: 2425 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2484
Query: 510 QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHK-GSVA 568
+++ + Q K +E V+ ++Q + E+ R++ EQ+R + +
Sbjct: 2485 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ------LREEQQRQQQQMEQERQRLVASM 2538
Query: 569 EQGSRRMSAAEQGSLRESVIEEPYQKSEQ--GPYGEIISEEQEDIGSTSQSRKDSILKST 626
E+ RR AE+G R+ +E Q+ EQ E+++EE + + Q ++ +
Sbjct: 2539 EEARRRQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2595
Query: 627 KYGEPITSEYI 637
+ E +T+ +
Sbjct: 2596 AHSEEVTASQV 2606
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/245 (22%), Positives = 110/245 (44%), Gaps = 32/245 (13%)
Query: 453 QRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEP----------------GTHTES 496
Q+ + AE+ ++++++Q + T +QE +SV++ ++
Sbjct: 2071 QKRLQAEEKAHAFAVQQKEQELQQTLQQE---QSVLDQLRGEAEAARRAAEEAEEARVQA 2127
Query: 497 TLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRE- 555
E SRR + E E ++S EQ Q + + + +EQ ++R + AEQ + R+
Sbjct: 2128 EREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQK 2187
Query: 556 --SIAEQDRHKGSVAEQGSRRMSAAEQ--GSLRESVIEEPYQKS-EQGPYGEIISEEQED 610
+ AE ++HK AEQ R+ + EQ +LR + E +QK+ + +E E
Sbjct: 2188 QAADAEMEKHK-KFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2246
Query: 611 IGSTSQSRKD------SILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
SQ ++ + + +K I +E + L++K + ++ +EE ++ EE
Sbjct: 2247 ARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2306
Query: 665 VPTLS 669
LS
Sbjct: 2307 AARLS 2311
Score = 43.1 bits (100), Expect = 0.001
Identities = 60/294 (20%), Positives = 116/294 (39%), Gaps = 53/294 (18%)
Query: 413 NTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPE--QQRGVTAEQGPQRISIEEQ 470
N L TQ L E ++ K + + S E + R + E Q+ ++ E+
Sbjct: 2278 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2337
Query: 471 QQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQ-HKGSIEG 529
+K A QE + L Q +RRL ++E + E+ Q + ++E
Sbjct: 2338 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2397
Query: 530 QGPRRVSVSEQGSSRESVAEQGSRRESIAEQDR--------------HKGSVAEQGS--- 572
+ R++ +S + + + SR ++ AE+D H+ +A Q
Sbjct: 2398 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2457
Query: 573 -------RRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQ--------- 616
R+ S + LRE++ E +K + +++ + E++ + Q
Sbjct: 2458 VQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQA 2517
Query: 617 ------SRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
S KDS+L+ ++ E QEK EQ +++E+ + +L+EE
Sbjct: 2518 LQQSFLSEKDSLLQRERFIE-----------QEKAKLEQLFQDEVAKAQQLREE 2560
Score = 39.7 bits (91), Expect = 0.012
Identities = 56/273 (20%), Positives = 108/273 (39%), Gaps = 49/273 (17%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
L AN A + + + E Q L + E+Q+ + +R EEQ ++
Sbjct: 1663 LKANEALRLRLQAEEVAQQKSLAQAEA--------EKQKEEAEREARRRGKAEEQAVRQR 1714
Query: 476 PTAEQELYIESVIEPGT------------HTESTLEQGSSRRLLTEQETHR--ESTTEQG 521
AEQEL + + GT + EQG +R L E+E R
Sbjct: 1715 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1774
Query: 522 QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKG------SVAEQGSRRM 575
Q + +E + + + E + ++ AE+ SR S + R + +AE+ +R
Sbjct: 1775 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1834
Query: 576 SAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSE 635
+ AE+ + + EE + ++ +++E+ IG ++ + ++
Sbjct: 1835 ALAEEAKRQRQLAEEDAAR-QRAEAERVLAEKLAAIGEATRLKTEA-------------- 1879
Query: 636 YIEVPLQEKRSWEQTY----EEEIFLSSELQEE 664
E+ L+EK + + E+E F L+E+
Sbjct: 1880 --EIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1910
Score = 33.5 bits (75), Expect = 0.86
Identities = 52/296 (17%), Positives = 130/296 (43%), Gaps = 20/296 (6%)
Query: 406 DKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRI 465
++VL E + KT++++ + + + +R + + Q+R + + +
Sbjct: 1859 ERVLAEKLAAIGEATRLKTEAEI--ALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKA 1916
Query: 466 SIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQH-K 524
IEE+ + ++ EL + + E TL Q RR + E+ +++ E+ K
Sbjct: 1917 DIEERLAQLRKASDSELERQKGL-----VEDTLRQ---RRQVEEEILALKASFEKAAAGK 1968
Query: 525 GSIEGQ-GPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSL 583
+E + G R + + S+E + +R+ +A ++ + AE+ ++ AAE+ +
Sbjct: 1969 AELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2028
Query: 584 RE--SVIEEPYQ-KSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVP 640
R+ + +EE + K++ + +++ Q +++ K + E + ++
Sbjct: 2029 RQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQ-- 2086
Query: 641 LQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
Q+++ +QT ++E + +L+ E R E + VQ ++ +++E
Sbjct: 2087 -QKEQELQQTLQQEQSVLDQLRGEAEAARRAAE--EAEEARVQAEREAAQSRRQVE 2139
Score = 32.7 bits (73), Expect = 1.5
Identities = 41/191 (21%), Positives = 85/191 (44%), Gaps = 14/191 (7%)
Query: 452 QQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLE--QGSSRRLLTE 509
QQ AE+ + I+ E+++ K + L ++S E L+ Q + L+E
Sbjct: 2466 QQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSE 2525
Query: 510 QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHK-GSVA 568
+++ + Q K +E V+ ++Q + E+ R++ EQ+R + +
Sbjct: 2526 KDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ------LREEQQRQQQQMEQERQRLVASM 2579
Query: 569 EQGSRRMSAAEQGSLRESVIEEPYQKSEQ--GPYGEIISEEQEDIGSTSQSRKDSILKST 626
E+ RR AE+G R+ +E Q+ EQ E+++EE + + Q ++ +
Sbjct: 2580 EEARRRQHEAEEGVRRK---QEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2636
Query: 627 KYGEPITSEYI 637
+ E +T+ +
Sbjct: 2637 AHSEEVTASQV 2647
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 47.8 bits (112), Expect = 4e-05
Identities = 65/325 (20%), Positives = 128/325 (39%), Gaps = 24/325 (7%)
Query: 385 EINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTST 444
++ ELW ++ Q+ E + + K+ E ++ + E++
Sbjct: 284 QVEENELWNRLNQQQ-----------EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 332
Query: 445 PSPNPPEQQRGVTAEQGPQRISIEEQ-QQGKKPTAEQELYIESVIEPGTHTESTLEQGSS 503
Q+ + ++ R E ++ +K ++E+ E + E E+
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Query: 504 RRLLTEQETHRESTTEQG---QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQ 560
R L E+ +E EQ Q + I Q R+ ++ E + EQ E I EQ
Sbjct: 393 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ---EEKIREQ 449
Query: 561 DRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKD 620
++ E+ + E+ +E EE +++ E+ E I ++E + + +
Sbjct: 450 EKKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK 507
Query: 621 SILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKK 680
K + E I + ++ QE++ W Q EE+I E+ E + ++ E K+
Sbjct: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQ--EEKIREQEEMWREEEKMHEQEKIWEEEKR 565
Query: 681 EVQKDKPC--EPKSQKIEGKSWSGE 703
+ Q+DK E K ++ E K W E
Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQE 590
Score = 33.9 bits (76), Expect = 0.66
Identities = 51/252 (20%), Positives = 104/252 (41%), Gaps = 16/252 (6%)
Query: 423 KTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQEL 482
+ + K+ E ++ + E++ EQ+ + EQ + EE+ + ++ +E
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR-EQEEKMWRQEEKIREQEEMWREE- 550
Query: 483 YIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQ-G 541
E + E E Q ++ ++E RE + + + I Q +R E+
Sbjct: 551 --EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608
Query: 542 SSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYG 601
E + EQ E I EQ+ + EQ + E +E + E Q+ +
Sbjct: 609 KQEEKIREQ---EEKIQEQEE---KIREQEEKIREQEEMTQEQEEKMGE--QEEKMCEQE 660
Query: 602 EIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSE- 660
E + E++E + + ++ K + E I + + QE++ WEQ EE++ E
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ--EEKMCEQEEK 718
Query: 661 LQEEVPTLSRKD 672
+QE+ + R++
Sbjct: 719 MQEQEEKMRRQE 730
>gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sapiens]
Length = 1079
Score = 47.4 bits (111), Expect = 6e-05
Identities = 20/34 (58%), Positives = 26/34 (76%)
Query: 810 QAGVQWRNCSSLQPPTPGLKRSSHHRLLSNWDYR 843
+AG+QW + SSLQPP PG KR SH L ++W+YR
Sbjct: 995 RAGMQWCDLSSLQPPPPGFKRFSHLSLPNSWNYR 1028
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 47.0 bits (110), Expect = 8e-05
Identities = 157/784 (20%), Positives = 290/784 (36%), Gaps = 124/784 (15%)
Query: 53 KPEHTWKKNLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRD---NLAK------E 103
K E++ E Q + Q++ E L +LE A+K D N+AK E
Sbjct: 1836 KKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKE 1895
Query: 104 WF----NTDSMTLNNTAYLLDKLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDPINYLG 159
F N S + A + + L +E L V+ +K+ E D +K I L
Sbjct: 1896 RFLDVENELSRIRSEKASIEHEALY-----LEADLEVVQTEKLCLEKDNENKQKVIVCLE 1950
Query: 160 EYL--IRNNPNYI---------KDPGMSGYQRLMKEVTEDLKIYVPDTI-CNRVSKMKEN 207
E L + + N + K + MKE T++L+ + + + C +V++ +
Sbjct: 1951 EELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVK 2010
Query: 208 VKQNRKQRESIDKIKVKVANTRKQALQEQFDEWILDPKGM-IPKSVIQNVLQEFFQNPDF 266
K Q S D ++ T LQE+ D + + + K ++N + + + +
Sbjct: 2011 EKTELLQTLSSDVSELLKDKTH---LQEKLQSLEKDSQALSLTKCELENQIAQLNKEKEL 2067
Query: 267 KLG-SHCKQLDITDSTEPRLNKMEFTE--YISSHIKDLKSEMFEELLKHLCHSADEFREV 323
+ S Q +++S +LN + E + L+ +E + L ++ R
Sbjct: 2068 LVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVR 2127
Query: 324 IKADMRRQMFA-----------------------ELFLHCDHGKVGFLDRQRTLALLELF 360
I+AD ++Q+ EL + ++ ++ LD + + A +E
Sbjct: 2128 IEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETL 2187
Query: 361 YDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANH 420
+M RSL + E+ NLT+ + Q DK+L +LL
Sbjct: 2188 KTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQ---LSELDKLLSSFKSLLEEKE 2244
Query: 421 ASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQ 480
++ Q K L Q E V A G Q I ++ +Q P E+
Sbjct: 2245 QAEIQIKEESKTAVEMLQNQLK--------ELNEAVAALCGDQEI-MKATEQSLDPPIEE 2295
Query: 481 ELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQ 540
E + + IE + LE ++L Q+ +ES KG +E R + ++
Sbjct: 2296 EHQLRNSIEK---LRARLEADEKKQLCVLQQL-KESEHHADLLKGRVENL-ERELEIART 2350
Query: 541 GSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPY 600
++ + S+ E + + +G + S +E++ E ++ E+
Sbjct: 2351 NQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISE 2410
Query: 601 GEIISEEQEDI--------------GSTSQSRKDSILK--------------STKYGEPI 632
EII+ E+I ST+ + LK + K E
Sbjct: 2411 LEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQN 2470
Query: 633 TSEYIEVPLQEKRSWEQTYEEE----IFLSS-------ELQEEVPTLSRKDHFPETTKKE 681
S +E EK Q +E I L S E+++ L +KD K +
Sbjct: 2471 LSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQ 2530
Query: 682 VQKDKPCEPKSQKIEGKS--WSGEFFTCNWKMKYVTFEDEEQANLIYGNSRFTDLHSIIR 739
+Q + K ++EG+ W + N +++ +T E E++ ++ S+ L +
Sbjct: 2531 IQDQEQLVSKLSQVEGEHQLWKEQ----NLELRNLTVELEQKIQVL--QSKNASLQDTLE 2584
Query: 740 NIQS 743
+QS
Sbjct: 2585 VLQS 2588
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 46.2 bits (108), Expect = 1e-04
Identities = 39/139 (28%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Query: 451 EQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTE- 509
E++RG E+ + + +E++ ++P A +E +E+ + G T ++G L TE
Sbjct: 472 EEKRGAEEEEVEEPLGVEKKGGEEEPEATKEP-LEAERKGGEETLEAEKRGGEESLETEK 530
Query: 510 -QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVA 568
Q T + EQG +GS E Q ++E G E+ E +E Q++ G++
Sbjct: 531 TQGTEGDLNLEQGSREGS-ESQAEE---MNEAGPPLEANTETRPEKEGPQPQEKPVGALE 586
Query: 569 EQGSRRMSAAE-QGSLRES 586
E+G + +AAE QG L ++
Sbjct: 587 EEGVKPQTAAEGQGPLGDA 605
Score = 33.5 bits (75), Expect = 0.86
Identities = 43/173 (24%), Positives = 68/173 (39%), Gaps = 27/173 (15%)
Query: 468 EEQQQGKKPTAEQELYIESVIEPGTHT--------------ESTLE---QGSSRRLLTEQ 510
EE + +K AE+ + I S +PGT E LE +GS+ +L TE+
Sbjct: 388 EETWEAEKRKAEESMGIGSEEKPGTGRDEAEMSPVVERKGGEKKLELESRGSAEKLGTER 447
Query: 511 ETHRE----STTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGS 566
E E +G + EG +R + E+ V ++G E E +
Sbjct: 448 EGGEEPLGIERKVEGHLRAEKEGDEEKRGAEEEEVEEPLGVEKKGGEEE--PEATKEPLE 505
Query: 567 VAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRK 619
+G AE+ ES+ E QG G++ E+ GS SQ+ +
Sbjct: 506 AERKGGEETLEAEKRGGEESLETE----KTQGTEGDLNLEQGSREGSESQAEE 554
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 46.2 bits (108), Expect = 1e-04
Identities = 70/292 (23%), Positives = 119/292 (40%), Gaps = 34/292 (11%)
Query: 407 KVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRIS 466
K+LLE + AN +S + P++ K + + +P E + V +E S
Sbjct: 1236 KMLLEE---IKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSE------S 1286
Query: 467 IEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGS 526
+ ++ KKP L + T S E G ++ T+ + H+E + S
Sbjct: 1287 DSDSEESKKPRYRHRLLRHKL------TVSDGESGEEKK--TKPKEHKEVKGRNRRKVSS 1338
Query: 527 IEGQGP--RRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLR 584
+ + + VSE+ S E +R AE + ++ S ++ RR ++ S
Sbjct: 1339 EDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSS 1398
Query: 585 ESVI---EEPYQKSEQGPYGEIISEEQEDIGSTSQS----RKD--SILKSTKYGEPITSE 635
E+ EE +K E+ E EE+ED S+S RK ILK K +
Sbjct: 1399 ENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNA 1458
Query: 636 YIEVPLQEKRSWEQTYE-EEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDK 686
E + KR E+ E E++ E+++ PT P TTK + +D+
Sbjct: 1459 LKEEEERRKRIAEREREREKLREVIEIEDASPT-----KCPITTKLVLDEDE 1505
Score = 39.7 bits (91), Expect = 0.012
Identities = 65/309 (21%), Positives = 123/309 (39%), Gaps = 37/309 (11%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
+ NH + K D K +R S+ S + + ++G +A+ SI ++ K+
Sbjct: 719 IHTNHKTLYDLKTQAGKDD-KGKRKRKSSTSGSDFDTKKGKSAKS-----SIISKK--KR 770
Query: 476 PTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRV 535
T + +S +E + S + + + +S+ ++ K ++ QG + +
Sbjct: 771 QTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNL 830
Query: 536 SVSEQGSS----RESVAEQGSRRESIAEQD------------RHKGSVAEQGSRRMSAAE 579
S++GSS R+ E S E ++D + + S + G ++S E
Sbjct: 831 KTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKE 890
Query: 580 QG--SLRESVIEEPYQKSE--QGPYGEIISEEQEDIGS--TSQSRKDSILKSTKYGEPIT 633
Q SL + E +KS+ + + + + DI + + D + K
Sbjct: 891 QSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKG 950
Query: 634 SEYIEVPLQEKR---SWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEP 690
+E + P K+ EQ YE SS+ E++P HFP+ K+ E
Sbjct: 951 TEEKKKPSDFKKKVIKMEQQYES----SSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK 1006
Query: 691 KSQKIEGKS 699
KS+KI K+
Sbjct: 1007 KSKKIRDKT 1015
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 46.2 bits (108), Expect = 1e-04
Identities = 70/292 (23%), Positives = 119/292 (40%), Gaps = 34/292 (11%)
Query: 407 KVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRIS 466
K+LLE + AN +S + P++ K + + +P E + V +E S
Sbjct: 1274 KMLLEE---IKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSE------S 1324
Query: 467 IEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGS 526
+ ++ KKP L + T S E G ++ T+ + H+E + S
Sbjct: 1325 DSDSEESKKPRYRHRLLRHKL------TVSDGESGEEKK--TKPKEHKEVKGRNRRKVSS 1376
Query: 527 IEGQGP--RRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLR 584
+ + + VSE+ S E +R AE + ++ S ++ RR ++ S
Sbjct: 1377 EDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSS 1436
Query: 585 ESVI---EEPYQKSEQGPYGEIISEEQEDIGSTSQS----RKD--SILKSTKYGEPITSE 635
E+ EE +K E+ E EE+ED S+S RK ILK K +
Sbjct: 1437 ENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNA 1496
Query: 636 YIEVPLQEKRSWEQTYE-EEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDK 686
E + KR E+ E E++ E+++ PT P TTK + +D+
Sbjct: 1497 LKEEEERRKRIAEREREREKLREVIEIEDASPT-----KCPITTKLVLDEDE 1543
Score = 39.7 bits (91), Expect = 0.012
Identities = 65/309 (21%), Positives = 123/309 (39%), Gaps = 37/309 (11%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKK 475
+ NH + K D K +R S+ S + + ++G +A+ SI ++ K+
Sbjct: 757 IHTNHKTLYDLKTQAGKDD-KGKRKRKSSTSGSDFDTKKGKSAKS-----SIISKK--KR 808
Query: 476 PTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRV 535
T + +S +E + S + + + +S+ ++ K ++ QG + +
Sbjct: 809 QTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNL 868
Query: 536 SVSEQGSS----RESVAEQGSRRESIAEQD------------RHKGSVAEQGSRRMSAAE 579
S++GSS R+ E S E ++D + + S + G ++S E
Sbjct: 869 KTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKE 928
Query: 580 QG--SLRESVIEEPYQKSE--QGPYGEIISEEQEDIGS--TSQSRKDSILKSTKYGEPIT 633
Q SL + E +KS+ + + + + DI + + D + K
Sbjct: 929 QSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKG 988
Query: 634 SEYIEVPLQEKR---SWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEP 690
+E + P K+ EQ YE SS+ E++P HFP+ K+ E
Sbjct: 989 TEEKKKPSDFKKKVIKMEQQYES----SSDGTEKLPEREEICHFPKGIKQIKNGTTDGEK 1044
Query: 691 KSQKIEGKS 699
KS+KI K+
Sbjct: 1045 KSKKIRDKT 1053
>gi|148664240 hypothetical protein LOC146556 isoform 1 [Homo
sapiens]
Length = 440
Score = 46.2 bits (108), Expect = 1e-04
Identities = 22/34 (64%), Positives = 24/34 (70%)
Query: 810 QAGVQWRNCSSLQPPTPGLKRSSHHRLLSNWDYR 843
QAGVQWRN SLQP PG K+ S L S+WDYR
Sbjct: 363 QAGVQWRNLGSLQPLPPGFKQFSCLILPSSWDYR 396
>gi|7706635 cornulin [Homo sapiens]
Length = 495
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/184 (27%), Positives = 89/184 (48%), Gaps = 19/184 (10%)
Query: 439 EQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTES-- 496
EQ +S + +Q + T +Q E QG+ T++ + I+ GTHT++
Sbjct: 243 EQDSSHQTGRTSKQTQEATNDQNR---GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPT 299
Query: 497 -TLEQGSSRRLLTEQETHRESTTEQGQHKGS-IEGQGPRRVSVSEQGSSRESVAEQGSRR 554
T+EQ SS + + +EST GQ++G+ I GQG + S + G + + GS
Sbjct: 300 QTVEQDSSHQTGSTSTQTQEST--NGQNRGTEIHGQGRSQTSQAVTGGHTQ--IQAGSHT 355
Query: 555 ESIAEQDRHKGSVAEQGSRRMSAAEQGSLR-ESVIEEPYQKSEQGPYGEIISEEQEDIGS 613
E++ EQDR + +V+ G+R EQG + + + + + GE + Q G+
Sbjct: 356 ETV-EQDRSQ-TVSHGGAR-----EQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
Query: 614 TSQS 617
+++S
Sbjct: 409 STES 412
Score = 30.0 bits (66), Expect = 9.5
Identities = 21/98 (21%), Positives = 38/98 (38%), Gaps = 3/98 (3%)
Query: 522 QHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQG 581
Q GS+ + + ++ + A +G E + + +GS +G R QG
Sbjct: 100 QESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGS---RGQNRPGVQTQG 156
Query: 582 SLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRK 619
S Y + + E IS + + G T Q++K
Sbjct: 157 QATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
>gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens]
Length = 825
Score = 44.7 bits (104), Expect = 4e-04
Identities = 27/59 (45%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Query: 791 YVETEQEKMNALEQVSLC-RQAGVQWRNCSSLQPPTPGLKRSSHHRLLSNWDYRERRKF 848
+ + E+EKMNA SL Q GVQW + SSLQP T ++ S L S WDYR + F
Sbjct: 763 FAKFEKEKMNAKWDTSLSVAQPGVQWCDISSLQPLTSRFQQFSCLSLPSTWDYRVKILF 821
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 44.7 bits (104), Expect = 4e-04
Identities = 61/315 (19%), Positives = 116/315 (36%), Gaps = 40/315 (12%)
Query: 425 QSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYI 484
+ K ES ++ + + S P+Q+ EE++QG + E
Sbjct: 213 EEKTTESQEETVVMSLKNGQISSEEPKQE--------------EEREQGSDEISHHEKME 258
Query: 485 ESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSR 544
E E + LE R+ EQ+ + + + Q R E+ R
Sbjct: 259 EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMR 318
Query: 545 ESVAEQGSRRESIAEQDRHKGSVAEQ-GSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEI 603
E R+ I E+++ ++ AAE+ R+ + EE + +E+
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE---RQRIKEEEKRAAEERQRARA 375
Query: 604 ISEEQEDIGSTSQSR----KDSILKSTKY-GEPITSEYIEVPLQEKRSWEQTYEEEIFLS 658
EE+ + +++ K ++ TK GE + + + EK++ E + +
Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435
Query: 659 -------------SELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIEG----KSWS 701
+LQE+ PT +++ E KK+ + + + + +G KS +
Sbjct: 436 QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQN 495
Query: 702 GEFFTCNWKMKYVTF 716
GEF T K TF
Sbjct: 496 GEFMTHKLKHTENTF 510
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 44.3 bits (103), Expect = 5e-04
Identities = 106/512 (20%), Positives = 191/512 (37%), Gaps = 83/512 (16%)
Query: 228 TRKQALQEQFDEWILDPKGMIPKSVIQNV------LQEFFQNP--DFKLGSHCKQLDITD 279
+R + EQ DE + + +S Q + ++ F++P + S K+ +
Sbjct: 37 SRTSSFTEQLDEGTPNRESGDTQSFAQKLQLRVPSVESLFRSPIKESLFRSSSKESLVRT 96
Query: 280 STEPRLNKMEFTEYISSHIKDLKSEMFEELLKHLCHSADEFREVIKADMRRQMFAELFLH 339
S+ LN+++ +S D S+M E + +S +E + +RR E L
Sbjct: 97 SSRESLNRLDLDSSTASF--DPPSDMDSEAEDLVGNSDSLNKEQLIQRLRRM---ERSLS 151
Query: 340 CDHGKVGFLDRQRTLALLELFYDHSSQMLRSLLRNPRQWPFIEFEEINLTELWGDMDNQK 399
GK L + L+ +L + E+ EL D +K
Sbjct: 152 SYRGKYS------ELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELR-EELQMDQQAKK 204
Query: 400 HIYEGFDKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAE 459
H+ E FD L E + +S +TQ LL+ + P P Q T E
Sbjct: 205 HLQEEFDASLEEKDQYIS---VLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKE 261
Query: 460 QGPQRISIEEQQQGKKPTAEQELYIESVIEPGT--HTESTLEQGSSR------RLLTEQE 511
+ P+ E V+E GT T TL+Q R R +
Sbjct: 262 ENPESDG------------------EPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQ 303
Query: 512 THRESTTEQGQHKGSIEGQGPRRVSVSEQ------GSSRESVAEQGSRRESIAEQDRHKG 565
+H+E T K +++ Q R+ E+ + + + + I + ++ KG
Sbjct: 304 SHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKG 363
Query: 566 SVAEQGSRRM---------------SAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQED 610
V + R+M S +Q + + + E +KSE+ + EE E
Sbjct: 364 MVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAF-----EELEK 418
Query: 611 IGSTSQSRKDSILK-STKYGEPI-----TSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
ST+Q +++ K + E I TSE + LQ++ S + +E + + + EE
Sbjct: 419 ALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELS--RVKQEVVDVMKKSSEE 476
Query: 665 VPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
+K H E +KE + K + + ++ +
Sbjct: 477 QIAKLQKLHEKELARKEQELTKKLQTREREFQ 508
Score = 32.3 bits (72), Expect = 1.9
Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 9/101 (8%)
Query: 60 KNLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPR------DNLAKEWFNT---DSM 110
K E ++AR + M K+ D + +EL+KK ++KL + DN+ T
Sbjct: 2057 KRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKT 2116
Query: 111 TLNNTAYLLDKLLPTLVPGVENMLTQVEKKKVLTEADTPSK 151
TL + + L ++ + +E+ L + EK T TP K
Sbjct: 2117 TLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGTPYK 2157
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 44.3 bits (103), Expect = 5e-04
Identities = 62/294 (21%), Positives = 109/294 (37%), Gaps = 33/294 (11%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNP---------PEQQRGVT--------- 457
LSA+ AS+ K P P + R ++P P+P P RG T
Sbjct: 451 LSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRR 510
Query: 458 ---AEQGPQRISIEEQQQGKKPTA-EQELYIESVIEPGTHTESTLEQGSSRRLLTEQETH 513
A++ P E++ Q K+ + E+E + P T + E T
Sbjct: 511 KEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTD 570
Query: 514 RESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSR 573
T + P + + ++R +AE+ RR++ +++R E+ R
Sbjct: 571 AAVLTSPPAPAPPVTPSKPMAGTTDREEATR-LLAEK--RRQAREQRER------EEQER 621
Query: 574 RMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQE--DIGSTSQSRKDSILKSTKYGEP 631
R+ A +RE + + + EEQE + Q ++ + K + E
Sbjct: 622 RLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEA 681
Query: 632 ITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKD 685
+ E E E+ Q E+E + EE+ +RK ET +K+ K+
Sbjct: 682 RSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKE 735
Score = 40.0 bits (92), Expect = 0.009
Identities = 53/281 (18%), Positives = 105/281 (37%), Gaps = 32/281 (11%)
Query: 417 SANHASKTQSKLLESPDQPKL---NEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQG 473
+A K+QSK S ++ + + PSP P Q+ + P ++
Sbjct: 520 AAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPA 579
Query: 474 KKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPR 533
P + P T ++ + RLL E+ E+ + + ++ + +
Sbjct: 580 PAPP----------VTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDK 629
Query: 534 RVSVSEQGSSRESVAEQGSRRESIAEQD-RHKGSVAEQGSRRMSAAEQGSLRESVIEEPY 592
R+ + E+ AE+ + EQ+ R K ++ R+ ++ + S E
Sbjct: 630 RMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAER 689
Query: 593 QKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYE 652
Q+ E+ E ++QE + R + I+K T+ E + E + + + E
Sbjct: 690 QRLER----EKHFQQQEQERQERRKRLEEIMKRTRKSE----------VSETKQKQDSKE 735
Query: 653 EEIFLSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQ 693
SS P + + P K+ VQK++P + Q
Sbjct: 736 ANANGSS----PEPVKAVEARSPGLQKEAVQKEEPIPQEPQ 772
Score = 33.1 bits (74), Expect = 1.1
Identities = 35/169 (20%), Positives = 64/169 (37%), Gaps = 20/169 (11%)
Query: 431 SPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEP 490
SP P ++ TP PP + +++Q P Q G +P QE
Sbjct: 34 SPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQE--------- 84
Query: 491 GTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQ 550
ES + SR R++ + + S P V S+ +++ V +
Sbjct: 85 ----ESPSSEAKSRGPTPPAMGPRDARPPRRSSQPS-----PTAVPASDSPPTKQEVKKA 135
Query: 551 GSRRESIAE--QDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQ 597
G R + E ++R K A++ + +LRE ++E ++ E+
Sbjct: 136 GERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEE 184
>gi|21328446 hormone-sensitive lipase [Homo sapiens]
Length = 1076
Score = 43.9 bits (102), Expect = 6e-04
Identities = 58/210 (27%), Positives = 92/210 (43%), Gaps = 24/210 (11%)
Query: 422 SKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQE 481
S TQ K + +Q L +Q T P+ + E Q+ A+Q + S EE +KP +Q
Sbjct: 45 SNTQQK--PASNQRPLTQQET--PAQHDAESQKEPRAQQ--KSASQEEFLAPQKPAPQQS 98
Query: 482 LYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQG 541
YI+ V+ T E+ +QG L E T +E Q G G + E
Sbjct: 99 PYIQRVLL--TQQEAASQQGPG--LGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAE 154
Query: 542 SSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRM-----SAAEQGSLRE-----SVIEEP 591
S+ + A+ G++RE A + EQ ++ + ++QGSL E + E
Sbjct: 155 STPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQGAKSKQGSLTELGFLTKLQELS 214
Query: 592 YQKS--EQGPYGEII--SEEQEDIGSTSQS 617
Q+S E E + SE + D+GS+S +
Sbjct: 215 IQRSALEWKALSEWVTDSESESDVGSSSDT 244
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 43.1 bits (100), Expect = 0.001
Identities = 61/272 (22%), Positives = 109/272 (40%), Gaps = 18/272 (6%)
Query: 430 ESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIE 489
E PD+ +L + E+++ E+ + EE+++ +K E + E
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 490 PGTHTESTL-EQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVA 548
+ L E+ R L QE RE E+ Q + Q RR E+ +E
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 549 EQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQ 608
EQ RRE E+ R + EQ RR EQ RE +E ++ +Q + EQ
Sbjct: 323 EQQERREQ-QEERREQQLRREQEERR----EQQLRRE---QEEERREQQ------LRREQ 368
Query: 609 EDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTL 668
E+ Q R++ L+ + + + + Q +R + E+++ +L+ E L
Sbjct: 369 EEERREQQLRREQQLRREQ--QLRREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQL 425
Query: 669 SRKDHFPETTKKEVQKDKPCEPKSQKIEGKSW 700
R+ +K Q+ + K ++ E + W
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDW 457
Score = 39.7 bits (91), Expect = 0.012
Identities = 49/234 (20%), Positives = 99/234 (42%), Gaps = 16/234 (6%)
Query: 468 EEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSI 527
EE+ Q ++ E+E + + E E+ +RL EQ+ R+ E+ + +
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 528 EGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESV 587
Q RR E+ ++ EQ RRE +++ + E+ +++ ++ RE
Sbjct: 322 REQQERR-EQQEERREQQLRREQEERREQQLRREQEE----ERREQQLRREQEEERREQQ 376
Query: 588 IEEPYQ-KSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRS 646
+ Q + EQ E ++ + Q R++ L+ + + E QE+
Sbjct: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE---QQLRREQQLRREQEEER 433
Query: 647 WEQTYEE---EIFLSSELQEEVPTLSRKD----HFPETTKKEVQKDKPCEPKSQ 693
EQ +E+ E L E +E L R++ H E K+++++D+ E + +
Sbjct: 434 HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Score = 39.3 bits (90), Expect = 0.016
Identities = 68/338 (20%), Positives = 133/338 (39%), Gaps = 24/338 (7%)
Query: 363 HSSQMLRSLLRNPRQWPFIEFEEINLTELWGDM-DNQKHIYEGFDKVLLEMNTLLSANHA 421
++ L+ LR +Q E EE+ E Q+ Y +++ E LL
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 422 SKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQE 481
+ + + + K +Q+ PE++R E+ + +Q++ + E+E
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 482 LYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQG 541
E + L+Q + L E+E R E+ + Q ++ E+
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
Query: 542 SSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYG 601
+ R E+ R+E +Q+ + E RR E R+ EE Q+ E+
Sbjct: 1070 TRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE----RQCREEEELQQEEE---- 1121
Query: 602 EIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQE-----KRSWEQTYEEEIF 656
+++ EE+E + R+ + + + E + E ++ +E ++ E+ Y EE
Sbjct: 1122 QLLREERE------KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE-- 1173
Query: 657 LSSELQEEVPTLSRKDHFPETTKKEVQKDKPCEPKSQK 694
ELQ+E L R++ ++E Q + E + QK
Sbjct: 1174 --EELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Score = 38.9 bits (89), Expect = 0.021
Identities = 43/222 (19%), Positives = 91/222 (40%), Gaps = 18/222 (8%)
Query: 451 EQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQG--SSRRLLT 508
E++R E+ Q++ E++++ ++ QE E L+Q S ++L
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQE------------EEERLQQRLRSEQQLRR 540
Query: 509 EQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVA 568
EQE RE ++ + K + + +R+ ++ + + + RR+ ++++ +
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 569 EQGSRRMSAAEQGSLRESVI--EEPYQKSEQGPYGEIISEE--QEDIGSTSQSRKDSILK 624
+ EQ RE + EEP ++ Q EE Q+ + Q R++ LK
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 625 STKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVP 666
+ E + +E+R E EE+ ++ +P
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
Score = 38.5 bits (88), Expect = 0.027
Identities = 51/264 (19%), Positives = 106/264 (40%), Gaps = 17/264 (6%)
Query: 416 LSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQ-GK 474
LSA + Q + ++ + EQR P EQ+R E+ + +EE++Q +
Sbjct: 784 LSARPPLREQRERQLRAEERQQREQRF-LPEEEEKEQRRRQRREREKELQFLEEEEQLQR 842
Query: 475 KPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRR 534
+ A+Q E ++ + EQ ++ + E R+ K +++ Q +
Sbjct: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE 902
Query: 535 VSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQK 594
+ ++ E+ RR E+ + +Q ++ E+ R E Y+K
Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK 962
Query: 595 SEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKR------SWE 648
+ ++ +E++ +G + R+ + E + E L+E+R WE
Sbjct: 963 DK-----KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017
Query: 649 QTYEEEIFLSSELQEEVPTLSRKD 672
+ Y ++ ELQ+E L R++
Sbjct: 1018 RQYRKK----DELQQEEEQLLREE 1037
Score = 38.5 bits (88), Expect = 0.027
Identities = 109/593 (18%), Positives = 215/593 (36%), Gaps = 90/593 (15%)
Query: 46 DETELKSKPEHTWKKNLFERMEARAQAMQQKIIDKENLKKELEKKAEKKLPRDNLAKEWF 105
+E +L + T ++ ER + + +QQ+ +++ L++E EK+ ++ R +E
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQE--EEQLLREEPEKRRRQERERQCREEEEL 1116
Query: 106 NTDSMTLNNTAYLLDKLLPTLVPGVENMLTQVEKKKVLTEADTPSKFDP-INYLGEYLIR 164
+ E +L + +K+ E + + + + E L+R
Sbjct: 1117 QQEE---------------------EQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 165 NNPNYIKDPGMSGYQRLMKEVTEDLKIYVPDTICNRVSKMKENVKQNRKQRESIDKIKVK 224
P + Q L ++ E+ ++ + R + K ++ R+ RE + + K
Sbjct: 1156 EEPEKRRR------QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Query: 225 VANTRKQALQEQFDEWILDPKGMIPKSVIQNVL-------QEFFQNPDFKLGSHCKQLDI 277
+ Q +W +P+ +V N + ++F Q D +L Q D+
Sbjct: 1210 RKQRYRDEDQRSDLKWQWEPEK--ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDL 1267
Query: 278 T---------------------DSTEPRLNKMEFTEYISSHIKDLKSEMFEELLKHLCHS 316
D P ++E E + +D KS+ ++LL+
Sbjct: 1268 QHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE---E 1324
Query: 317 ADEFREVIKADMRRQMFAELFLHCDHGKVGFLDRQRTLALLELFYDHSSQML----RSLL 372
+E R + D + + +L + + +R R EL + + + L
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384
Query: 373 RNPRQWPFIEFEEINLTELWGDMDNQKHIYEGFDKVLLEMNTLLSANHASKTQSKLLESP 432
R R+ F++ E+ + + ++ + + D+ E LS + K E
Sbjct: 1385 RQERERKFLKEEQQLRCQ-----EREQQLRQDRDRKFREEEQQLSRQERDR---KFREEE 1436
Query: 433 DQPKLNE-QRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQ-------GKKPTAEQELYI 484
Q + E +R Q+R + Q + E+QQ K EQ+L
Sbjct: 1437 QQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRR 1496
Query: 485 ESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSR 544
+ E ++ + L EQ+ HR+ Q Q K E Q RR E+G R
Sbjct: 1497 QERDRKFREQELRSQEPERKFLEEEQQLHRQ----QRQRKFLQEEQQLRR---QERGQQR 1549
Query: 545 ESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQ 597
++ R E Q+R + ++ Q R E+ +R E + + EQ
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Score = 35.8 bits (81), Expect = 0.17
Identities = 51/273 (18%), Positives = 105/273 (38%), Gaps = 10/273 (3%)
Query: 433 DQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGT 492
++ + + T P EQ R + ++ +++ K+ EQE +
Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ 938
Query: 493 HTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGS 552
E L + +R E+E + Q + + G+ P + E+ E
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 553 RRESIAEQDRHKGSVAE-----QGSRRMSAAEQGSLRESVIEEPYQKSEQ--GPYGEIIS 605
E + ++R K E + + E+ LRE + Q+ E+ E+
Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058
Query: 606 EEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQE--KRSWEQTYEEEIFLSSELQE 663
EE++ +G ++R+ L+ E + E L+E ++ Q E + ELQ+
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 664 EVPTLSRKDHFPETTKKEVQKDKPCEPKSQKIE 696
E L R++ + ++E+++ E + Q+ E
Sbjct: 1119 EEEQLLREER-EKRRRQELERQYREEEEVQQEE 1150
Score = 34.3 bits (77), Expect = 0.51
Identities = 47/240 (19%), Positives = 96/240 (40%), Gaps = 24/240 (10%)
Query: 425 QSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYI 484
+ +LL+ ++ +L ++R E++R Q + EE+++ ++ EQE +
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRD-------QLLKREEERRQQRLKREQEERL 598
Query: 485 ESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSR 544
E ++ LEQ R EQ RE E+ + Q + E+ +
Sbjct: 599 EQRLK--REEVERLEQEERR----EQRLKREEPEEERR-------QQLLKSEEQEERRQQ 645
Query: 545 ESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEII 604
+ EQ RRE +++ + E+ +R+ + RE + E Q+ + I
Sbjct: 646 QLRREQQERREQRLKREEEE----ERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 605 SEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEE 664
+ Q + S + +R+ + + E + + +R E ++EE + QEE
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Score = 34.3 bits (77), Expect = 0.51
Identities = 55/301 (18%), Positives = 120/301 (39%), Gaps = 24/301 (7%)
Query: 395 MDNQKHIYEGFDKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQR 454
+ ++ Y +++ E LL ++ + +L + + +Q PE++R
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 455 GVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHR 514
E+ + +Q++ + E+E +E E ++Q + L E E R
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Query: 515 ESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSR- 573
E+ Q++ E Q + E+ R E+ R E ++ + K ++ R
Sbjct: 1163 RQELER-QYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Query: 574 ----RMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYG 629
+ ++ ++R++ + +++EQ + ++ + D QS++D
Sbjct: 1222 DLKWQWEPEKENAVRDNKVYCKGRENEQ--FRQLEDSQLRD----RQSQQDL-------- 1267
Query: 630 EPITSEYIEVPL-QEKRSWEQT---YEEEIFLSSELQEEVPTLSRKDHFPETTKKEVQKD 685
+ + E E QE+R W+Q + EE L E Q+E RK + +E +++
Sbjct: 1268 QHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327
Query: 686 K 686
K
Sbjct: 1328 K 1328
Score = 32.3 bits (72), Expect = 1.9
Identities = 53/274 (19%), Positives = 105/274 (38%), Gaps = 24/274 (8%)
Query: 429 LESPDQPKLNEQRTSTPSPNPPEQQRGVTA-EQGPQRISIEEQQQGKKPTAEQELYIESV 487
L+ ++ L E+R + Q R +Q +++ EE ++ ++ E++
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC----- 1110
Query: 488 IEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESV 547
E L+Q + L E+E R E+ + Q ++ E R
Sbjct: 1111 -----REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 548 AEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEE 607
E+ R E +Q+ + EQ RR Q RE EE ++ + Y + ++
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQ--YREE--EELQRQKRKQRYRD--EDQ 1219
Query: 608 QEDIGSTSQSRKDSILKSTK-YGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVP 666
+ D+ + K++ ++ K Y + +E + Q+ ++ L E QE
Sbjct: 1220 RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR 1279
Query: 667 TLSRKD------HFPETTKKEVQKDKPCEPKSQK 694
R+ HFPE + E ++ K + + +K
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Score = 32.0 bits (71), Expect = 2.5
Identities = 50/244 (20%), Positives = 103/244 (42%), Gaps = 29/244 (11%)
Query: 451 EQQ--RGVTAEQGPQRISIEEQ-QQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLL 507
EQQ R E+ Q++ E+Q ++ ++ EQ+L E + + ++L
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 508 TEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSV 567
EQ+ RE E+ + K E + EQ R EQ RR+ + ++ +
Sbjct: 421 REQQLRREQEEERHEQKHEQERR--------EQRLKR----EQEERRDWLKREEETERHE 468
Query: 568 AEQGSRRMSAAEQGSLRES--VIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKS 625
E+ +++ ++ RE +EE ++ +Q + + EQE+ R++ LK
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE-------RREQRLKR 521
Query: 626 TKYGEPI-----TSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPETTKK 680
+ E + + + + +E+R EEE L E +E+ +++ + K+
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Query: 681 EVQK 684
E ++
Sbjct: 582 EEER 585
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/34 (58%), Positives = 24/34 (70%)
Query: 810 QAGVQWRNCSSLQPPTPGLKRSSHHRLLSNWDYR 843
QAG++W + SSLQ TPG KRS H L S+W YR
Sbjct: 367 QAGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYR 400
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/164 (23%), Positives = 64/164 (39%), Gaps = 8/164 (4%)
Query: 509 EQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVA 568
E+E E E+G+ +G EG+G E+G E+G + ++
Sbjct: 983 EEEGEGEGEEEEGEEEGEEEGEG------EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE 1036
Query: 569 EQGSRRMSAAE-QGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTK 627
E+G E +G E+ ++ E+G Y E EE E + I S K
Sbjct: 1037 EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVK 1096
Query: 628 YGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTLSRK 671
YG+ T + V + EQ + + S L + P+ S+K
Sbjct: 1097 YGKHKTYQKKSVTNTQGNGKEQRSKMPV-QSKRLLKNGPSGSKK 1139
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/170 (25%), Positives = 66/170 (38%), Gaps = 9/170 (5%)
Query: 451 EQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQ 510
E+ G E+G EE+ +GK +E E E G E E G E+
Sbjct: 898 EEGEGEGEEEGEGE-GEEEEGEGKGEEEGEEGEGEGEEEEG---EGEGEDGEGEG--EEE 951
Query: 511 ETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQ 570
E E E+G+ +G EG+G +G E E E E+ +G E+
Sbjct: 952 EGEWEGEEEEGEGEGEEEGEGEGEEG---EGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Query: 571 GSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKD 620
G E+G + V E + + GE EE+E G ++R++
Sbjct: 1009 GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRN 1058
Score = 37.4 bits (85), Expect = 0.060
Identities = 24/130 (18%), Positives = 55/130 (42%)
Query: 490 PGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAE 549
P + T E+GSS + E + ++G+ + G+G + ++ E+ R+ +
Sbjct: 651 PEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQ 710
Query: 550 QGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQE 609
+ RE +++R++ E+ RE E+ + E+G E+ E ++
Sbjct: 711 EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770
Query: 610 DIGSTSQSRK 619
+ G + +
Sbjct: 771 EEGERKKEER 780
Score = 37.4 bits (85), Expect = 0.060
Identities = 40/169 (23%), Positives = 60/169 (35%), Gaps = 8/169 (4%)
Query: 451 EQQRGVTAEQGPQRISIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQ 510
E +R G + EE QG+ E E E E G +E+G R E+
Sbjct: 772 EGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEE 831
Query: 511 ETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQ 570
E E +G+ + EG+ E+ E+G E E++ +G E+
Sbjct: 832 EGEGEEEEGEGEEEEG-EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEE 890
Query: 571 G-------SRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIG 612
G E+G E + E+G GE EE+E G
Sbjct: 891 GEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEG 939
Score = 36.6 bits (83), Expect = 0.10
Identities = 50/252 (19%), Positives = 94/252 (37%), Gaps = 33/252 (13%)
Query: 411 EMNTLLSANHASKTQSKLLESPDQPKLNEQRTST--PSPNPPEQQRGVTAEQGP---QRI 465
E N + KT+ + D+ +++E + + + + PE + T E+G +
Sbjct: 610 EENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHW 669
Query: 466 SIEEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKG 525
EE+++G+K E+ G + L E+E ++ E+ + K
Sbjct: 670 QDEEREKGEKDKGRGEME---------------RPGEGEKELAEKEEWKKRDGEEQEQKE 714
Query: 526 SIEGQGPRRVSVSEQGSSR---ESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGS 582
+G R E+G E E+G R E++ +G E+G E+
Sbjct: 715 REQGHQKERNQEMEEGGEEEHGEGEEEEGDRE----EEEEKEGEGKEEGEGEEVEGEREK 770
Query: 583 LRESVIEEPYQKSEQGPYGEIISEEQEDIGSTSQSRKDSILKSTKYGEPITSEYIEVPLQ 642
EE +K E+ E EE+ D G + + + + G + +E
Sbjct: 771 ------EEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKG 824
Query: 643 EKRSWEQTYEEE 654
E+ E+ E E
Sbjct: 825 EREEEEEEGEGE 836
Score = 34.3 bits (77), Expect = 0.51
Identities = 37/145 (25%), Positives = 53/145 (36%), Gaps = 7/145 (4%)
Query: 468 EEQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTEQETHRESTTEQGQHKGSI 527
EE+ +GK +E E E G E E+G E+E E E+G+ +G
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEGEEG-EGEGEEEEGEGEG---EEEGEGEGEEEEGEGEGEE 906
Query: 528 EGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAEQGSRRMSAAEQGSLRESV 587
EG+G E E +G E E+ +G E +G E
Sbjct: 907 EGEGEGEEEEGEGKGEEEGEEGEGEGEE---EEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963
Query: 588 IEEPYQKSEQGPYGEIISEEQEDIG 612
E + +G GE EE+E G
Sbjct: 964 GEGEEEGEGEGEEGEGEGEEEEGEG 988
Score = 31.6 bits (70), Expect = 3.3
Identities = 35/166 (21%), Positives = 62/166 (37%), Gaps = 4/166 (2%)
Query: 451 EQQRGVTAEQGPQRISIE-EQQQGKKPTAEQELYIESVIEPGTHTESTLEQGSSRRLLTE 509
+++R E+G + E E+++G + E++ G E E+ R E
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779
Query: 510 QETHRESTTEQGQHKGSIEGQGPRRVSVSEQGSSRESVAEQGSRRESIAEQDRHKGSVAE 569
+ E E+G E + R E+G E + + E E++ +G E
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Query: 570 ---QGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIG 612
+ E+G + E + E+G GE EE+E G
Sbjct: 840 GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG 885
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/325 (22%), Positives = 138/325 (42%), Gaps = 40/325 (12%)
Query: 403 EGFDKVLLEMNTLLSANHASKTQSKLLESPDQPKLNEQRTSTPSPNPPEQQRGVTAEQGP 462
EGFD++ LE++ L + + + L+ +Q +L + E++RG TA +
Sbjct: 230 EGFDEMRLELDQLEVREKQLRERMQQLDRENQ-ELRAAVSQQGEQLQTERERGRTAAEDN 288
Query: 463 QRISI---EEQQQGKKPTAEQELYIE------------SVIEPGTHTESTLEQGSSRRLL 507
R++ E Q+Q + A Q E + E HT + + L
Sbjct: 289 VRLTCLVAELQKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLA 348
Query: 508 TEQETHRESTTEQGQHKGSIEG---QGPRRVSVSEQGSSR---------ESVAEQGSRRE 555
E E R+S ++ QH S G ++ + R + + E G + +
Sbjct: 349 QELEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQ 408
Query: 556 SIAEQDRHKGSVAEQGSRRMSAAEQGSLRESVIEEPYQKSEQGPYGEIISEEQEDIGSTS 615
++ E++R K E+ +R+ SA + ++E ++E + S + E+ ++E G
Sbjct: 409 AL-ERERTK---VEEVNRQQSAQLEQLVKELQLKEDARASLERLVKEMAPLQEELSGKGQ 464
Query: 616 QSRKDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFP 675
++ D + + + TS + E + +R +Q EE+ L++EV +L+R+ F
Sbjct: 465 EA--DQLWRRLQELLAHTSSWEEELAELRREKKQQQEEK----ELLEQEVRSLTRQLQFL 518
Query: 676 ETTKKEVQKDKPC--EPKSQKIEGK 698
ET +V + E K Q I+ K
Sbjct: 519 ETQLAQVSQHVSDLEEQKKQLIQDK 543
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,824,820
Number of Sequences: 37866
Number of extensions: 1530815
Number of successful extensions: 7871
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 370
Number of HSP's that attempted gapping in prelim test: 6412
Number of HSP's gapped (non-prelim): 1435
length of query: 856
length of database: 18,247,518
effective HSP length: 111
effective length of query: 745
effective length of database: 14,044,392
effective search space: 10463072040
effective search space used: 10463072040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.