Guide to the Human Genome
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Search of human proteins with 222352175

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222352175 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 2 [Homo sapiens]
         (366 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222352175 nuclear factor of kappa light polypeptide gene enha...   755   0.0  
gi|222352173 nuclear factor of kappa light polypeptide gene enha...   745   0.0  
gi|222352179 nuclear factor of kappa light polypeptide gene enha...   709   0.0  
gi|222352177 nuclear factor of kappa light polypeptide gene enha...   699   0.0  
gi|148746195 trichohyalin [Homo sapiens]                               49   7e-06
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             49   7e-06
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...    48   1e-05
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa...    48   1e-05
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa...    48   1e-05
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa...    48   1e-05
gi|117320531 nuclear factor of kappa light polypeptide gene enha...    47   2e-05
gi|117320540 nuclear factor of kappa light polypeptide gene enha...    47   2e-05
gi|117320527 nuclear factor of kappa light polypeptide gene enha...    47   2e-05
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...    47   2e-05
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...    47   2e-05
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...    47   2e-05
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap...    47   2e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             47   3e-05
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti...    47   4e-05
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    46   6e-05
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    45   1e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       45   1e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    45   1e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    45   1e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    45   1e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    45   1e-04
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni...    44   2e-04
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit...    44   2e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04

>gi|222352175 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells inhibitor-like 1 isoform 2 [Homo
           sapiens]
          Length = 366

 Score =  755 bits (1950), Expect = 0.0
 Identities = 366/366 (100%), Positives = 366/366 (100%)

Query: 1   MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD 60
           MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
Sbjct: 1   MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD 60

Query: 61  VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL 120
           VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
Sbjct: 61  VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL 120

Query: 121 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGDASHETQEP 180
           LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGDASHETQEP
Sbjct: 121 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGDASHETQEP 180

Query: 181 ESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEE 240
           ESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEE
Sbjct: 181 ESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEE 240

Query: 241 ELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAA 300
           ELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAA
Sbjct: 241 ELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAA 300

Query: 301 ALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNR 360
           ALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNR
Sbjct: 301 ALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNR 360

Query: 361 HAEALK 366
           HAEALK
Sbjct: 361 HAEALK 366


>gi|222352173 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells inhibitor-like 1 isoform 1 [Homo
           sapiens]
          Length = 381

 Score =  745 bits (1924), Expect = 0.0
 Identities = 366/381 (96%), Positives = 366/381 (96%), Gaps = 15/381 (3%)

Query: 1   MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD 60
           MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
Sbjct: 1   MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD 60

Query: 61  VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL 120
           VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
Sbjct: 61  VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL 120

Query: 121 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQG--------- 171
           LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQG         
Sbjct: 121 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV 180

Query: 172 ------DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE 225
                 DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE
Sbjct: 181 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE 240

Query: 226 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV 285
           EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
Sbjct: 241 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV 300

Query: 286 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG 345
           PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
Sbjct: 301 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG 360

Query: 346 RVMGAVTALSQALNRHAEALK 366
           RVMGAVTALSQALNRHAEALK
Sbjct: 361 RVMGAVTALSQALNRHAEALK 381


>gi|222352179 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells inhibitor-like 1 isoform 4 [Homo
           sapiens]
          Length = 343

 Score =  709 bits (1831), Expect = 0.0
 Identities = 343/343 (100%), Positives = 343/343 (100%)

Query: 24  MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL 83
           MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL
Sbjct: 1   MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL 60

Query: 84  LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG 143
           LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG
Sbjct: 61  LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG 120

Query: 144 WGPPWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQR 203
           WGPPWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQR
Sbjct: 121 WGPPWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQR 180

Query: 204 EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTR 263
           EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTR
Sbjct: 181 EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTR 240

Query: 264 AGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQ 323
           AGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQ
Sbjct: 241 AGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQ 300

Query: 324 VRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK 366
           VRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK
Sbjct: 301 VRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK 343


>gi|222352177 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells inhibitor-like 1 isoform 3 [Homo
           sapiens]
          Length = 358

 Score =  699 bits (1805), Expect = 0.0
 Identities = 343/358 (95%), Positives = 343/358 (95%), Gaps = 15/358 (4%)

Query: 24  MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL 83
           MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL
Sbjct: 1   MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL 60

Query: 84  LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG 143
           LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG
Sbjct: 61  LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG 120

Query: 144 WGPPWDSAEEEEEDDASKEREWRQKLQG---------------DASHETQEPESFSAWSD 188
           WGPPWDSAEEEEEDDASKEREWRQKLQG               DASHETQEPESFSAWSD
Sbjct: 121 WGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSD 180

Query: 189 RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR 248
           RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR
Sbjct: 181 RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR 240

Query: 249 RAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPP 308
           RAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPP
Sbjct: 241 RAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPP 300

Query: 309 LEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK 366
           LEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK
Sbjct: 301 LEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK 358


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 33/107 (30%), Positives = 58/107 (54%), Gaps = 3/107 (2%)

Query: 147 PWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSD-RLAREHAQKCQQQQREA 205
           P    E +EE++  ++ E RQ+L+ +   E Q+ +        R  +E  ++ QQ++R  
Sbjct: 265 PQRQRELQEEEEQLRKLE-RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323

Query: 206 EGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 252
           +  RR  + E   Q  R+++EE+R  ++  R +EEE RE + RR QE
Sbjct: 324 QQERREQQEERREQQLRREQEERR-EQQLRREQEEERREQQLRREQE 369



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 30/121 (24%), Positives = 61/121 (50%), Gaps = 11/121 (9%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           EE+++    +E++ R+K + +   + +E            RE  ++ +QQ+   E   R 
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEE-----------RREQQERREQQEERREQQLRR 341

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHP 271
            + E   Q  R+++EE+R  ++  R +EEE RE + RR Q+   +++ +  +   RE+  
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401

Query: 272 R 272
           R
Sbjct: 402 R 402



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 38/126 (30%), Positives = 64/126 (50%), Gaps = 12/126 (9%)

Query: 152 EEEEEDDASKE---REWRQKLQGDA---SHETQEPESFSAWSDR--LAREHAQKCQQQQR 203
           EEEE++   +E   R+  +KLQ +      E QE E      +R  L RE  ++ QQQQR
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR 299

Query: 204 EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTR 263
                RR  +     +  R++++E+R  ++  R ++EE RE + RR QE   +++ +  +
Sbjct: 300 ----LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQ 355

Query: 264 AGPREE 269
              R E
Sbjct: 356 EEERRE 361



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 5/123 (4%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQ--REAEGSR 209
           E  E+ +  +E++ R++ Q +   +    E       +L RE  ++ ++QQ  RE E  R
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372

Query: 210 RPPRAEGSSQSWRQQE--EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPR 267
           R  +     Q  R+Q+   EQ+L RE+   +E++LR  +  R ++ L  RE +  R    
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL-RREQQLRREQEE 431

Query: 268 EEH 270
           E H
Sbjct: 432 ERH 434



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 38/128 (29%), Positives = 61/128 (47%), Gaps = 12/128 (9%)

Query: 149 DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
           D  + EEE +  ++   +Q+L+ D     QE E    W   L  E  ++ +QQ+R  +  
Sbjct: 456 DWLKREEETERHEQERRKQQLKRD-----QEEERRERW---LKLEEEERREQQERREQQL 507

Query: 209 RRPPRAEGSSQSWRQQEEE---QRLFRE-RARAKEEELRESRARRAQEALGDREPKPTRA 264
           RR        +  RQ+EEE   QRL  E + R ++EE RE   +R +E   ++E +  R 
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567

Query: 265 GPREEHPR 272
              +E  R
Sbjct: 568 KREQEERR 575



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 48/193 (24%), Positives = 75/193 (38%), Gaps = 28/193 (14%)

Query: 151 AEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQ-REAEGSR 209
           +EE+EE    ++++ R++ Q       +  E       RL REH ++ ++Q+  E E  +
Sbjct: 636 SEEQEE---RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692

Query: 210 RPPRAEGSSQSWRQQEEEQ----------RLFRERARAKEEELRESRARRAQEALGDREP 259
              R +     W+ Q E +          R  ++  + + +E  E R RR  E     E 
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE 752

Query: 260 KPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYL 319
           +  R    EE  R           D  W        E     L AR PPL EQ    R L
Sbjct: 753 RAHRQQQEEEQRR-----------DFTWQWQAEEKSERGRQRLSAR-PPLREQ--RERQL 798

Query: 320 RVQQVRWHPDRFL 332
           R ++ +    RFL
Sbjct: 799 RAEERQQREQRFL 811



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/110 (26%), Positives = 59/110 (53%), Gaps = 11/110 (10%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSR-- 209
            +EEEE+   +ERE R++ + +  +  +E E      ++L RE  +K ++Q+RE +  +  
Sbjct: 907  QEEEEELQREEREKRRRQEQERQY--REEEQLQQEEEQLLREEREKRRRQERERQYRKDK 964

Query: 210  ----RPPRAEGSSQSWRQQEEEQRLFRERARAKEEE---LRESRARRAQE 252
                +  +  G     R+++E ++ +RE    ++EE   LRE R +R ++
Sbjct: 965  KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/105 (27%), Positives = 57/105 (54%), Gaps = 3/105 (2%)

Query: 149  DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
            +  ++EEE    +ERE R++ + +  +  +E E      ++L RE  +K ++Q+ E +  
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQY--REEEEVQQEEEQLLREEPEKRRRQELERQYR 1171

Query: 209  RRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL-RESRARRAQE 252
                  +   Q  R+++E++R  RER   +EEEL R+ R +R ++
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD 1216



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 3/125 (2%)

Query: 148 WDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG 207
           W   EEEE  +  + RE  Q+L+ +     ++        +RL ++  +  QQ +RE E 
Sbjct: 488 WLKLEEEERREQQERRE--QQLRREQEERREQRLKRQEEEERL-QQRLRSEQQLRREQEE 544

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPR 267
            R         +   Q+  EQRL RE+   +++ L+    RR Q    ++E +  +   R
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604

Query: 268 EEHPR 272
           EE  R
Sbjct: 605 EEVER 609



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 6/138 (4%)

Query: 120 LLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQ----KLQGDASH 175
           L  R  S   ++ +  E   Q+L         +E  E    +E+E R+    K + +   
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587

Query: 176 ETQEPESFSAWSDRLAREHAQKCQQQQR-EAEGSRRPPRAEGSSQSWRQQEEEQRLFRER 234
           +  + E       RL RE  ++ +Q++R E    R  P  E   Q  + +E+E+R  +++
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR-QQQ 646

Query: 235 ARAKEEELRESRARRAQE 252
            R +++E RE R +R +E
Sbjct: 647 LRREQQERREQRLKREEE 664



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 16/129 (12%)

Query: 149  DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
            +  ++EEE    +ERE R++ + +  +  +E        ++L RE  +K ++Q+RE    
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEE--ELQQEEEQLLREEPEKRRRQERE---- 1107

Query: 209  RRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL-----RESRARRAQEALGDREPKPTR 263
             R  R E       QQEEEQ L  ER + + +EL      E   ++ +E L   EP+  R
Sbjct: 1108 -RQCREEEE----LQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162

Query: 264  AGPREEHPR 272
                E   R
Sbjct: 1163 RQELERQYR 1171



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 7/116 (6%)

Query: 149 DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
           +  EE  E    +E++ R++ Q     + +  +       +L RE   + +QQ R  +  
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR-EQQLRREQQLRREQQLRREQQL 425

Query: 209 RRPPRAEGSSQSWRQQEEEQRLFRER------ARAKEEELRESRARRAQEALGDRE 258
           RR    E   Q   Q+  EQRL RE+       + +EE  R  + RR Q+   D+E
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 16/129 (12%)

Query: 149  DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
            +  ++EEE    +ERE R++ + +  +  ++ +      ++L RE  +K + Q+RE    
Sbjct: 994  EELQQEEEQLLREEREKRRRQEWERQY--RKKDELQQEEEQLLREEREKRRLQERE---- 1047

Query: 209  RRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL-----RESRARRAQEALGDREPKPTR 263
             R  R E       QQEEEQ L  ER   + +EL     +E   ++ +E L   EP+  R
Sbjct: 1048 -RQYREEEE----LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102

Query: 264  AGPREEHPR 272
               RE   R
Sbjct: 1103 RQERERQCR 1111



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 5/128 (3%)

Query: 149 DSAEEEEEDDASKEREWR--QKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAE 206
           +  EE  E    +E+E R  Q+L+ +   E +E +      +   RE   + +QQ R  +
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERRE-QQLRREQEEERREQQLRREQQLRREQ 387

Query: 207 GSRRPPRAEGSSQSWRQQE--EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRA 264
             RR  +     Q  R+Q+   EQ+L RE+   +E++LR  +     E   ++E +  R 
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447

Query: 265 GPREEHPR 272
              +E  R
Sbjct: 448 KREQEERR 455



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 6/118 (5%)

Query: 154 EEEDDASKERE-WRQKLQGDASHETQ-EPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E+ D   ++ E WRQ+ +     E + E E   +       E   + Q ++RE    RR 
Sbjct: 162 EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRK 221

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREE 269
            R E   Q   ++E + R+F+E    KE   RE+  R+ +E L + EP+  R    EE
Sbjct: 222 GREEKQQQ---RRERQDRVFQEEEE-KEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 32/138 (23%), Positives = 63/138 (45%), Gaps = 14/138 (10%)

Query: 149 DSAEEEEEDDASKER----EWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQRE 204
           D  +E++E   S+E+    +WR +L+ +         +  A  ++L +E     ++++  
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913

Query: 205 AEGSRRPPRAEGSSQSWR-----QQEEEQRLFRERARAKEEEL-----RESRARRAQEAL 254
               R   R +   + +R     QQEEEQ L  ER + + +E      ++ + ++ +E L
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973

Query: 255 GDREPKPTRAGPREEHPR 272
              EP+  R   RE+  R
Sbjct: 974 LGEEPEKRRRQEREKKYR 991



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 30/108 (27%), Positives = 46/108 (42%), Gaps = 5/108 (4%)

Query: 149 DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
           +  EE  E    +E+E  ++ Q     +    E       +L RE   + +QQ R  +  
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 413

Query: 209 RRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGD 256
           RR  +     Q  R+QEEE+       +  E+E RE R +R QE   D
Sbjct: 414 RREQQLRREQQLRREQEEER-----HEQKHEQERREQRLKREQEERRD 456



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 7/121 (5%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E+  + +  + R+W ++ +    HE +  +       +L R+  ++ +++  + E   R 
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQ------QLKRDQEEERRERWLKLEEEERR 497

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHP 271
            + E   Q  R+++EE+R  R + R +EEE  + R R  Q+   ++E +  +   REE  
Sbjct: 498 EQQERREQQLRREQEERREQRLK-RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556

Query: 272 R 272
           R
Sbjct: 557 R 557



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 2/119 (1%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQ-EPESFSAWSDRLAREHAQKCQQQQREAEGSRR 210
           +EE  +   K +E  ++LQ     E Q   E        L RE  ++ +Q++RE    R 
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREE 269
                       ++  +QRL RE+    E+ L+     R ++    RE +  R  P EE
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE-ERREQRLKREEPEEE 628



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           + EE +   +E    Q+L+ +   E +  +   +      R+   + +QQ+R  +  +R 
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPK 260
              E   Q  +++ EE+R        +E+EL E    +A+E +  R PK
Sbjct: 663 EEEERLEQRLKREHEEER--------REQELAEEEQEQARERIKSRIPK 703



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 29/109 (26%), Positives = 54/109 (49%), Gaps = 4/109 (3%)

Query: 154  EEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPR 213
            EEE    +ER  + + +     E +E +      DR   E  Q+ ++Q+R+ +   +  R
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509

Query: 214  AEGSSQSWRQQEEEQRLFRERARAK--EEELRESRARRAQEALGDREPK 260
            ++   + +   EEEQ+L R++ + K  +EE +  R  R Q+   DR+ K
Sbjct: 1510 SQEPERKF--LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK 1556



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 12/111 (10%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
            +++EE    +E E R++ + +  +  +E E      ++L RE  +K ++Q+ E +  ++ 
Sbjct: 967  QQKEEQLLGEEPEKRRRQEREKKY--REEEELQQEEEQLLREEREKRRRQEWERQYRKKD 1024

Query: 212  PRAEGSSQSWRQQEEEQRLF-RERARAKEEELR---------ESRARRAQE 252
               +   Q  R++ E++RL  RER   +EEEL+         E   RR QE
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 31/122 (25%), Positives = 59/122 (48%), Gaps = 3/122 (2%)

Query: 149  DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
            D  ++EEE    +ERE +++LQ +   + +E E      ++L  E  +  ++Q+ E +  
Sbjct: 1024 DELQQEEEQLLREERE-KRRLQ-ERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081

Query: 209  RRPPRAEGSSQSWRQQ-EEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPR 267
            +     +   Q  R++ E+ +R  RER   +EEEL++   +  +E    R  +      R
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141

Query: 268  EE 269
            EE
Sbjct: 1142 EE 1143



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 30/116 (25%), Positives = 53/116 (45%), Gaps = 13/116 (11%)

Query: 156  EDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQR---EAEGSRRPP 212
            ED   ++R+ +Q LQ    H   E +      +R   +  ++ QQ+ R   E E   R  
Sbjct: 1254 EDSQLRDRQSQQDLQ----HLLGEQQ------ERDREQERRRWQQRDRHFPEEEQLEREE 1303

Query: 213  RAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
            + E   +  + QEE+Q L  ER   +  +  + + R  ++ L +RE +P R   R+
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 10/111 (9%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
            E EE+  + +ER+ + +L+       ++   F     +L R+  Q+  +Q+R+       
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD------- 1618

Query: 212  PRAEGSSQSWRQQEEEQRLFRERARAK--EEELRESRARRAQEALGDREPK 260
             R     +   Q+ EEQ+L R+    K  EEE +  R  R Q+   DR+ K
Sbjct: 1619 -RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 28/113 (24%), Positives = 55/113 (48%), Gaps = 11/113 (9%)

Query: 149  DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
            +  ++EEE    +E E R++ + +   + +E E      ++L RE  +K ++Q+ E +  
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERE--RQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141

Query: 209  RRPPRAEGSSQSWRQQEEE------QRLFRERARAKEEE---LRESRARRAQE 252
                  +   Q  R++ E+      +R +RE    ++EE   LRE + +R QE
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 4/102 (3%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHE--TQEPESFSAWSDRLAREHAQKCQQQQREAEGSR 209
            E++E D   + R W+Q+ +     E   +E +  +   DR ++E  Q  ++++ E    +
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332

Query: 210  RPPRAEGSSQSWRQQEEEQRLFRER--ARAKEEELRESRARR 249
               R     +   Q+ EEQ L R+    + +EEELR     R
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR 1374



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 52/200 (26%), Positives = 85/200 (42%), Gaps = 9/200 (4%)

Query: 153  EEEEDDASKEREWRQKLQGDASHETQEPES-FSAWSDRLAREHAQKCQQQQREAEGSRRP 211
            EEE+    +ERE R+ L+ +     QE E       DR  RE  Q+  +Q+R+ +     
Sbjct: 1378 EEEQRLRRQERE-RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436

Query: 212  PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHP 271
             +     +  +  EEEQ+L +ER R   EE +  + R  Q+    R+ +  +    E+  
Sbjct: 1437 QQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL--HRQERDRKFLEEEQQL 1494

Query: 272  RGAGRGSLWRFGDVPWPCPGGG--DPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPD 329
            R   R   +R  ++    P     + E        +   L+E+  LRR  R QQ R   D
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554

Query: 330  RFL---QRFRSQIETWELGR 346
            R     ++ R + E  +L R
Sbjct: 1555 RKFREEEQLRQEREEQQLSR 1574



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 28/129 (21%)

Query: 155  EEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRA 214
            EE+   +ERE              E +  S  SDR  RE  Q  Q+++   E   RP + 
Sbjct: 1775 EEEQLRQERE--------------EQQLRSQESDRKFREEEQLRQERE---EQQLRPQQR 1817

Query: 215  EG----SSQSWRQQEEEQRLFRER---ARAKEEELRESRARRAQEALGDREPKPTRAGP- 266
            +G      +  + +E+EQRL +ER    RA+E+   + ++RR ++ L   E +  R    
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1877

Query: 267  ---REEHPR 272
               REEH R
Sbjct: 1878 RKLREEHIR 1886



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 20/99 (20%), Positives = 50/99 (50%), Gaps = 2/99 (2%)

Query: 154 EEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPR 213
           E+E++  +++  +++ +     E +E   +    +   R   ++ +QQ +  +   R  R
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487

Query: 214 AEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 252
                +  R++++E+R   ++ R ++EE RE R +R +E
Sbjct: 488 WLKLEEEERREQQERR--EQQLRREQEERREQRLKRQEE 524



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 19/125 (15%)

Query: 147  PWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQ---- 202
            P +   E EE   +K R+ + + +     E +E +     +DR  RE  Q  Q+++    
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353

Query: 203  REAEGSRRPPRAE-----------GSSQSWRQQEEEQRLFRE----RARAKEEELRESRA 247
            R  E  R+    E              Q  R+QE E++  +E    R + +E++LR+ R 
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413

Query: 248  RRAQE 252
            R+ +E
Sbjct: 1414 RKFRE 1418



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 5/120 (4%)

Query: 153 EEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPP 212
           EEE+    + RE R K + +   +            RL RE  ++ +Q+ +  E  R   
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612

Query: 213 RAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPR 272
                 +  R++ EE+R  +     ++EE R+ + RR Q+     E +  R    EE  R
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ-----ERREQRLKREEEEER 667



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 26/101 (25%), Positives = 48/101 (47%), Gaps = 9/101 (8%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           +EE+      E +W+++ +     + +E      W  + A E +++ +Q+      S RP
Sbjct: 735 QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ-AEEKSERGRQRL-----SARP 788

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 252
           P  E   +  R +E +Q   RE+    EEE +E R R+ +E
Sbjct: 789 PLREQRERQLRAEERQQ---REQRFLPEEEEKEQRRRQRRE 826



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 25/116 (21%), Positives = 57/116 (49%), Gaps = 8/116 (6%)

Query: 149  DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
            +  ++EEE    +ERE R++ + +  +  ++ +      ++L  E  +K ++Q+RE +  
Sbjct: 934  EQLQQEEEQLLREEREKRRRQERERQY--RKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991

Query: 209  RRPPRAEGSSQSWRQQEEE------QRLFRERARAKEEELRESRARRAQEALGDRE 258
                  +   Q  R++ E+      +R +R++   ++EE +  R  R +  L +RE
Sbjct: 992  EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047



 Score = 36.2 bits (82), Expect = 0.048
 Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 17/89 (19%)

Query: 196 QKCQQQQRE-AEGSRRPPRAEGSSQS---------WRQQEEEQRLFRERARAKEEELRES 245
           QK Q+Q+RE AEG  +  + E   Q          WRQ++E Q   RE  RA+EE+L+  
Sbjct: 139 QKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQE--REERRAEEEQLQSC 196

Query: 246 RARRA-----QEALGDREPKPTRAGPREE 269
           +         +E L  RE    R   REE
Sbjct: 197 KGHETEEFPDEEQLRRRELLELRRKGREE 225



 Score = 35.8 bits (81), Expect = 0.062
 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 7/94 (7%)

Query: 195 AQKCQQQQREAEGSRRPPRAEGSSQSW----RQQEEEQRLFRERARAKEEELRESRARRA 250
           AQ C     +A G     RA    +      R+QEE+QR F  R R  EEE  + R ++ 
Sbjct: 82  AQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKR 141

Query: 251 QE---ALGDREPKPTRAGPREEHPRGAGRGSLWR 281
           QE    L + E +  +    E+  R      LWR
Sbjct: 142 QEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175



 Score = 35.4 bits (80), Expect = 0.081
 Identities = 36/134 (26%), Positives = 61/134 (45%), Gaps = 13/134 (9%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSD---RLAREHAQKCQQQQREAEGS 208
            E EE+   S+E + + + +     E +E +      D   R   E  Q  +Q+QR  +  
Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER 1841

Query: 209  RRPPRAEGS-SQSWRQQEEEQRLFRE----RARAKEEELRESRARRAQEALGDREPKPTR 263
             R  RAE   +   + + EEQ L++E    R + +E +LRE   RR Q+     E +  +
Sbjct: 1842 DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK----EEQRHRQ 1897

Query: 264  AGP-REEHPRGAGR 276
             G  + +  +G GR
Sbjct: 1898 VGEIKSQEGKGHGR 1911



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 16/123 (13%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWS-DRLAREHAQKCQQQQREAEGSRR 210
            +E E++   ++  +R+ L+ +     +E +       DR  RE  Q  Q+++ +   S+ 
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQE 1792

Query: 211  PPRAEGSSQSWRQQEEEQRLFRERARAK-------------EEELRESRAR--RAQEALG 255
              R     +  RQ+ EEQ+L  ++   K             E+ LR+ R R  RA+E   
Sbjct: 1793 SDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFA 1852

Query: 256  DRE 258
             +E
Sbjct: 1853 TQE 1855



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 7/114 (6%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQ---QREAEGS 208
           EEE+  D + + +  +K +      +  P        +L  E  Q+ +Q+   + E +  
Sbjct: 760 EEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQ 819

Query: 209 RRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE----LRESRARRAQEALGDRE 258
           RR  R E   +    +EEEQ   RERA+  +EE      +   RR+QE   D++
Sbjct: 820 RRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 12/114 (10%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
            E E++    ++R++R++ Q     E +E +      DR  RE  Q+ ++Q+RE +  +  
Sbjct: 1656 EREQQLRHDRDRKFREEEQ--LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ-- 1711

Query: 212  PRAEGSSQSWRQQEEEQRLFRERARAKEEELRES--RARRAQEALGDREPKPTR 263
                   Q  R+QE E R FRE  + ++E  +E   R  R ++ L + + +P R
Sbjct: 1712 -----EEQQLRRQELE-RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPER 1759



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 31/136 (22%), Positives = 59/136 (43%), Gaps = 22/136 (16%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E++   +    RE + + +     E Q         ++    H QK +Q++RE    +R 
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE----QRL 447

Query: 212 PRAEGSSQSWRQQEEE----------QRLFRER--------ARAKEEELRESRARRAQEA 253
            R +   + W ++EEE          Q+L R++         + +EEE RE + RR Q+ 
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507

Query: 254 LGDREPKPTRAGPREE 269
             ++E +  +   R+E
Sbjct: 508 RREQEERREQRLKRQE 523



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 10/131 (7%)

Query: 155 EEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQ---QREAEGSRRP 211
           EE+   + R+ RQ    +   E  E E  S   +RL +   Q+  ++   QR+    R  
Sbjct: 130 EEEPGQRRRQKRQ----EQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREE 185

Query: 212 PRAEGSS-QSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEH 270
            RAE    QS +  E E+  F +  + +  EL E R +  +E    R  +  R    EE 
Sbjct: 186 RRAEEEQLQSCKGHETEE--FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE 243

Query: 271 PRGAGRGSLWR 281
                R ++ R
Sbjct: 244 KEWRKRETVLR 254



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 21/124 (16%)

Query: 162 EREWRQKLQGDAS-----HETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEG 216
           + E R +  G  S      + ++   F     +L  E  Q+ +Q+++E E       AEG
Sbjct: 96  DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL----AEG 151

Query: 217 SSQSWRQQEEEQR--------LFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
             QS +Q+  EQR        L+R+R   +E E R +   + Q   G      T   P E
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHE----TEEFPDE 207

Query: 269 EHPR 272
           E  R
Sbjct: 208 EQLR 211



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 8/96 (8%)

Query: 155  EEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRA 214
            EE+   +ERE +   + +   + +E E       R   E  Q+ ++Q+RE +  +     
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK----- 1394

Query: 215  EGSSQSWRQQEEEQRLFRERARA-KEEELRESRARR 249
                Q  R QE EQ+L ++R R  +EEE + SR  R
Sbjct: 1395 --EEQQLRCQEREQQLRQDRDRKFREEEQQLSRQER 1428



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 9/112 (8%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E+EE  +   +RE  ++L+ +   +  + E        L RE  ++ Q+ +RE E  R  
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE-ERLE 599

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTR 263
            R +        +EE +RL +E  R +  +  E    R Q+ L   E +  R
Sbjct: 600 QRLK--------REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR 643



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 8/125 (6%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLA----REHAQKCQ---QQQRE 204
            EEEE     +++ +R + Q        EPE  +A  D       RE+ Q  Q    Q R+
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260

Query: 205  AEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRA 264
             +  +      G  Q  R +E+E+R +++R R   EE +  R  + +    DR+ +  + 
Sbjct: 1261 RQSQQDLQHLLGEQQE-RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQ 1319

Query: 265  GPREE 269
              REE
Sbjct: 1320 LLREE 1324



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 22/113 (19%), Positives = 50/113 (44%), Gaps = 7/113 (6%)

Query: 156  EDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAE 215
            E++    R+ R +   +    +QEPE       R   E  Q+  +QQR+ +  +   +  
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPE-------RKFLEEEQQLHRQQRQRKFLQEEQQLR 1541

Query: 216  GSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
               +  +++++  R FRE  + ++E   +  +R+ ++     E +  R   +E
Sbjct: 1542 RQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 30/133 (22%), Positives = 55/133 (41%), Gaps = 12/133 (9%)

Query: 152  EEEEE---DDASKEREWRQKLQGDASHETQEPESFSAWSDR-------LAREHAQKCQQQ 201
            +EEE+   ++  K R   ++ Q     E Q+ E      +R       L R++ ++ + Q
Sbjct: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147

Query: 202  QREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARA--KEEELRESRARRAQEALGDREP 259
            Q E +  R  P      +  RQ  EE+ L +E  +   +E+E R     R      + + 
Sbjct: 1148 QEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR 1207

Query: 260  KPTRAGPREEHPR 272
            +  +   R+E  R
Sbjct: 1208 QKRKQRYRDEDQR 1220



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 8/124 (6%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREA---EGS 208
            E  ++    ++R++R++ Q     E +E +      DR  R   QK ++Q++E    E  
Sbjct: 1544 ERGQQRRQDRDRKFREEEQ--LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE 1601

Query: 209  RRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
            ++  R EG  Q    ++E  R FRE  +  +E   +   R+ ++     E    R   RE
Sbjct: 1602 QQLRRQEGQQQL---RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE 1658

Query: 269  EHPR 272
            +  R
Sbjct: 1659 QQLR 1662



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 21/114 (18%), Positives = 48/114 (42%), Gaps = 6/114 (5%)

Query: 155  EEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRA 214
            E++   + +E +Q+L+ +   + +E E        L     Q+  +Q+R+ +     P+ 
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFREDEQL------LQEREEQQLHRQERDRKFLEEEPQL 1652

Query: 215  EGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
                +  + + +  R FRE  +  +E   +   R+ ++     E +  R   RE
Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 23/101 (22%), Positives = 44/101 (43%), Gaps = 4/101 (3%)

Query: 153  EEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPP 212
            +E +    +ER+ + +       E +E +      DR   E   + ++Q+RE +      
Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD 1666

Query: 213  RAEGSSQSWRQQEEEQRLFRE----RARAKEEELRESRARR 249
            R     +   Q+ EEQ+L R+    + R +E++LR     R
Sbjct: 1667 RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 21/114 (18%)

Query: 153  EEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQRE-----AEG 207
            EEE+    +ERE R+ LQ +     QE E      ++L +E  Q+  ++Q        E 
Sbjct: 1695 EEEQQLRRQERE-RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753

Query: 208  SRRPPRAEGS------------SQSWRQQEEEQRLFRERARAK---EEELRESR 246
              RP R E               +  RQ+ EEQ+L  + +  K   EE+LR+ R
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807



 Score = 29.3 bits (64), Expect = 5.8
 Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 15/146 (10%)

Query: 152  EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQK------CQQQQREA 205
            E EE+    +ER+ + + +       +    F     +L R+  ++        +Q+ E 
Sbjct: 1678 EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQ 1737

Query: 206  EGSRRPPR-----AEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR---RAQEA-LGD 256
            E  RR  R      E   +  R++++ +R  R+R   +EE+LR+ R     R+QE+    
Sbjct: 1738 EQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797

Query: 257  REPKPTRAGPREEHPRGAGRGSLWRF 282
            RE +  R    E+  R   R   +R+
Sbjct: 1798 REEEQLRQEREEQQLRPQQRDGKYRW 1823


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 40/108 (37%), Positives = 57/108 (52%), Gaps = 12/108 (11%)

Query: 177 TQEPESFS---AWSDRLAREHAQKCQQQQREAEGSRRPPRAE-----GSSQSWRQQEEEQ 228
           T +PE  +   A   RLARE  +K ++++RE E   R  R E        ++ R++EE +
Sbjct: 473 TTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESR 532

Query: 229 RLFRERARAKEEELR---ESRA-RRAQEALGDREPKPTRAGPREEHPR 272
           RL  E+AR KEE+L+   E RA R  +EA   +  K   A  REE  R
Sbjct: 533 RLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAER 580



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/160 (25%), Positives = 67/160 (41%), Gaps = 13/160 (8%)

Query: 149 DSAEEEEEDDASKEREWRQKLQGDASHE--TQEPESFSAWSDRLAREHAQKCQQQQ---- 202
           +  E E  +    ER+ R++L    + E  T+  E         ARE  ++ Q+Q     
Sbjct: 495 EKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEAEQAREKEEQLQRQAEERA 554

Query: 203 -REAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEAL-GDREPK 260
            RE E + R  R +      R++ E  R  RE+   +EE+ R  R +R +E +   R  +
Sbjct: 555 LREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLERKKRLEEIMKRTRRTE 614

Query: 261 PTRAGPREEHPRGAGRGSLWRFGDV-PWPC----PGGGDP 295
            T     ++      +G+L    +V   PC    PG G P
Sbjct: 615 ATDKKTSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKP 654



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 159 ASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSS 218
           A K R  R++ + +     ++ E      + LA+  A++ +  +RE E  R         
Sbjct: 484 AEKRRLAREQREKEERERREQEELERQKREELAQRVAEE-RTTRREEESRRLEAEQAREK 542

Query: 219 QSWRQQEEEQRLFRER---ARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPR 272
           +   Q++ E+R  RER    RA+ ++  E+R R   E +     K  +   REE  R
Sbjct: 543 EEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQ---REEQER 596



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 14/102 (13%)

Query: 189 RLAREHAQKCQQQ--QREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELR--- 243
           RLARE  ++ ++Q   RE     R  RA    Q + +  EE++   E  R KEE  R   
Sbjct: 68  RLARERREEREKQLAAREIVWLEREERAR---QHYEKHLEERKKRLEEQRQKEERRRAAV 124

Query: 244 -ESRARRAQEALGDREPKPTRA-----GPREEHPRGAGRGSL 279
            E R +R +E     E    R       P+++H R +  GSL
Sbjct: 125 EEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSL 166


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 1/126 (0%)

Query: 148 WDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG 207
           +  +EEEEE++ S E      L G+++          A  +R      Q+ +QQQRE E 
Sbjct: 323 YSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEE 382

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKE-EELRESRARRAQEALGDREPKPTRAGP 266
            +R   AE   +   Q+E+ +RL  ++ R KE  + +E   RR  E    RE +  RA  
Sbjct: 383 HKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEH 442

Query: 267 REEHPR 272
            +E+ R
Sbjct: 443 EQEYKR 448



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 29/123 (23%), Positives = 50/123 (40%), Gaps = 16/123 (13%)

Query: 151 AEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRR 210
           AE ++  +  KE+  R + Q     E ++ +          RE  +  ++Q R  E  RR
Sbjct: 389 AERQKRIEEQKEQRRRLEEQQRREKELRKQQE---------REQRRHYEEQMRREEERRR 439

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEH 270
              AE   +  R+Q EEQR    +A   + +L++ R          +E +P    P   +
Sbjct: 440 ---AEHEQEYKRKQLEEQR----QAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHY 492

Query: 271 PRG 273
             G
Sbjct: 493 KEG 495


>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
           sapiens]
          Length = 1276

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 1/126 (0%)

Query: 148 WDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG 207
           +  +EEEEE++ S E      L G+++          A  +R      Q+ +QQQRE E 
Sbjct: 323 YSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEE 382

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKE-EELRESRARRAQEALGDREPKPTRAGP 266
            +R   AE   +   Q+E+ +RL  ++ R KE  + +E   RR  E    RE +  RA  
Sbjct: 383 HKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEH 442

Query: 267 REEHPR 272
            +E+ R
Sbjct: 443 EQEYKR 448



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 29/123 (23%), Positives = 50/123 (40%), Gaps = 16/123 (13%)

Query: 151 AEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRR 210
           AE ++  +  KE+  R + Q     E ++ +          RE  +  ++Q R  E  RR
Sbjct: 389 AERQKRIEEQKEQRRRLEEQQRREKELRKQQE---------REQRRHYEEQMRREEERRR 439

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEH 270
              AE   +  R+Q EEQR    +A   + +L++ R          +E +P    P   +
Sbjct: 440 ---AEHEQEYKRKQLEEQR----QAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHY 492

Query: 271 PRG 273
             G
Sbjct: 493 KEG 495


>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
           sapiens]
          Length = 1323

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 1/126 (0%)

Query: 148 WDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG 207
           +  +EEEEE++ S E      L G+++          A  +R      Q+ +QQQRE E 
Sbjct: 323 YSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEE 382

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKE-EELRESRARRAQEALGDREPKPTRAGP 266
            +R   AE   +   Q+E+ +RL  ++ R KE  + +E   RR  E    RE +  RA  
Sbjct: 383 HKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEH 442

Query: 267 REEHPR 272
            +E+ R
Sbjct: 443 EQEYKR 448



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 29/123 (23%), Positives = 50/123 (40%), Gaps = 16/123 (13%)

Query: 151 AEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRR 210
           AE ++  +  KE+  R + Q     E ++ +          RE  +  ++Q R  E  RR
Sbjct: 389 AERQKRIEEQKEQRRRLEEQQRREKELRKQQE---------REQRRHYEEQMRREEERRR 439

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEH 270
              AE   +  R+Q EEQR    +A   + +L++ R          +E +P    P   +
Sbjct: 440 ---AEHEQEYKRKQLEEQR----QAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHY 492

Query: 271 PRG 273
             G
Sbjct: 493 KEG 495


>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
           sapiens]
          Length = 1331

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 1/126 (0%)

Query: 148 WDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG 207
           +  +EEEEE++ S E      L G+++          A  +R      Q+ +QQQRE E 
Sbjct: 323 YSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEE 382

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKE-EELRESRARRAQEALGDREPKPTRAGP 266
            +R   AE   +   Q+E+ +RL  ++ R KE  + +E   RR  E    RE +  RA  
Sbjct: 383 HKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEH 442

Query: 267 REEHPR 272
            +E+ R
Sbjct: 443 EQEYKR 448



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 29/123 (23%), Positives = 50/123 (40%), Gaps = 16/123 (13%)

Query: 151 AEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRR 210
           AE ++  +  KE+  R + Q     E ++ +          RE  +  ++Q R  E  RR
Sbjct: 389 AERQKRIEEQKEQRRRLEEQQRREKELRKQQE---------REQRRHYEEQMRREEERRR 439

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEH 270
              AE   +  R+Q EEQR    +A   + +L++ R          +E +P    P   +
Sbjct: 440 ---AEHEQEYKRKQLEEQR----QAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHY 492

Query: 271 PRG 273
             G
Sbjct: 493 KEG 495


>gi|117320531 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells 2 isoform a [Homo sapiens]
          Length = 900

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 23/45 (51%), Positives = 27/45 (60%)

Query: 68  PLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDA 112
           PLH A        +  LLR+GADPA  DRHGD+A+H A R G  A
Sbjct: 530 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGA 574


>gi|117320540 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells 2 isoform b [Homo sapiens]
          Length = 899

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 23/45 (51%), Positives = 27/45 (60%)

Query: 68  PLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDA 112
           PLH A        +  LLR+GADPA  DRHGD+A+H A R G  A
Sbjct: 530 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGA 574


>gi|117320527 nuclear factor of kappa light polypeptide gene
           enhancer in B-cells 2 isoform b [Homo sapiens]
          Length = 899

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 23/45 (51%), Positives = 27/45 (60%)

Query: 68  PLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDA 112
           PLH A        +  LLR+GADPA  DRHGD+A+H A R G  A
Sbjct: 530 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGA 574


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 1/126 (0%)

Query: 148 WDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG 207
           +  +EEEEE++ S E      L G+++          A  +R      Q+ +QQQRE E 
Sbjct: 323 YSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEE 382

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKE-EELRESRARRAQEALGDREPKPTRAGP 266
            +R   AE   +   Q+E+ +RL  ++ R KE  + +E   RR  E    RE +  RA  
Sbjct: 383 HKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEH 442

Query: 267 REEHPR 272
            +E+ R
Sbjct: 443 EQEYIR 448


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 1/126 (0%)

Query: 148 WDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG 207
           +  +EEEEE++ S E      L G+++          A  +R      Q+ +QQQRE E 
Sbjct: 323 YSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEE 382

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKE-EELRESRARRAQEALGDREPKPTRAGP 266
            +R   AE   +   Q+E+ +RL  ++ R KE  + +E   RR  E    RE +  RA  
Sbjct: 383 HKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEH 442

Query: 267 REEHPR 272
            +E+ R
Sbjct: 443 EQEYIR 448


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 1/126 (0%)

Query: 148 WDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG 207
           +  +EEEEE++ S E      L G+++          A  +R      Q+ +QQQRE E 
Sbjct: 323 YSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEE 382

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKE-EELRESRARRAQEALGDREPKPTRAGP 266
            +R   AE   +   Q+E+ +RL  ++ R KE  + +E   RR  E    RE +  RA  
Sbjct: 383 HKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEH 442

Query: 267 REEHPR 272
            +E+ R
Sbjct: 443 EQEYIR 448


>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
           sapiens]
          Length = 1360

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 1/126 (0%)

Query: 148 WDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG 207
           +  +EEEEE++ S E      L G+++          A  +R      Q+ +QQQRE E 
Sbjct: 323 YSGSEEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEE 382

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKE-EELRESRARRAQEALGDREPKPTRAGP 266
            +R   AE   +   Q+E+ +RL  ++ R KE  + +E   RR  E    RE +  RA  
Sbjct: 383 HKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEH 442

Query: 267 REEHPR 272
            +E+ R
Sbjct: 443 EQEYIR 448


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 4/110 (3%)

Query: 150 SAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSR 209
           S EE  E +  KERE  ++L+ +   E ++         +   +  +K Q++QRE E  R
Sbjct: 500 SPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKER 559

Query: 210 RPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREP 259
           +    E   +  RQ+E+E+ L + + + KE EL + R  + +E +  REP
Sbjct: 560 KQ---EKEKELERQKEKEKELQKMKEQEKECELEKER-EKLEEKIEPREP 605



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 14/116 (12%)

Query: 147 PWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAE 206
           P+ S ++  ++D   ++  RQ+ +  A+ E            R  RE  ++  ++QR+A 
Sbjct: 431 PFPSKQQVADEDEIWKQRRRQQSEISAAVERA----------RKRREEEERRMEEQRKAA 480

Query: 207 GSRRPPRAE---GSSQSWRQQEEEQRLFRERARAKEEEL-RESRARRAQEALGDRE 258
            + +  R +   G  +     EE +   RE+ R +E+EL +E    R +E   DRE
Sbjct: 481 CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRE 536



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 21/103 (20%), Positives = 42/103 (40%), Gaps = 4/103 (3%)

Query: 153 EEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPP 212
           EE+   A  E+  R   +     +   PE          RE  ++ +++Q +     R  
Sbjct: 474 EEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREK 533

Query: 213 RAEGSSQSWRQQEEEQ----RLFRERARAKEEELRESRARRAQ 251
             E   +  ++ E+EQ     + +ER + KE+EL   + +  +
Sbjct: 534 DRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKE 576



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 12/72 (16%)

Query: 199 QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALG--D 256
           Q++++++E S    RA       R++EEE+R+  +R  A  E+L     +R  E LG  +
Sbjct: 447 QRRRQQSEISAAVERARK-----RREEEERRMEEQRKAACAEKL-----KRLDEKLGILE 496

Query: 257 REPKPTRAGPRE 268
           ++P P     RE
Sbjct: 497 KQPSPEEIRERE 508


>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
           [Homo sapiens]
          Length = 213

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 1/121 (0%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E E++ D   ER+  ++   D   ET+        +DR      ++ +Q++RE E  R  
Sbjct: 63  EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHP 271
            R E   +  R+++ ++   RER R  E E    R R+ ++   +RE +  R   R+   
Sbjct: 123 ER-EKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRET 181

Query: 272 R 272
           +
Sbjct: 182 K 182



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 10/127 (7%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDR-------LAREHA---QKCQQQ 201
           + E E +  KERE  +  + D   + Q+        DR       + RE     +  +++
Sbjct: 85  QRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRER 144

Query: 202 QREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKP 261
           +R+AE  R   R   +    R++E E++  RER R  +E  R +   R ++   DR+   
Sbjct: 145 ERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDR 204

Query: 262 TRAGPRE 268
            R   RE
Sbjct: 205 QRESERE 211



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 26/122 (21%), Positives = 53/122 (43%), Gaps = 2/122 (1%)

Query: 149 DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
           +S  E+   +  ++R+  +  + D   E ++         R       + ++ +RE +  
Sbjct: 36  ESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKE 95

Query: 209 RRPPR-AEGSSQSWRQQEEEQRLFRERARAKEEEL-RESRARRAQEALGDREPKPTRAGP 266
           R   R  E   +  +Q+E E    R+R R K++E+ RE +  R  +   +R+ +  R   
Sbjct: 96  RETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETG 155

Query: 267 RE 268
           RE
Sbjct: 156 RE 157



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 5/118 (4%)

Query: 153 EEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPP 212
           E E  D  +ER      + D + E++  +  S   +R  +   ++ +++ R+ E  ++  
Sbjct: 13  ETETMDRQRERRRETDRERDRAKESKTEDRHS---ERDRQRDRERNRERDRDREREKQTD 69

Query: 213 RAEGSSQSWRQQEEEQRLFRERARAKEEEL-RESRARRAQEALGDREPKPTRAGPREE 269
           R EG  Q  R+++ +++   ER R KE E  R +   R ++   +RE +  R   RE+
Sbjct: 70  R-EGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREK 126



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 149 DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
           ++  E + +D  +ERE  +K + +   ET+E E  +       RE  +K + +QRE+E  
Sbjct: 153 ETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRK-RDRQRESERE 211

Query: 209 R 209
           R
Sbjct: 212 R 212


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
            theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 45/165 (27%), Positives = 67/165 (40%), Gaps = 19/165 (11%)

Query: 107  RQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWR 166
            R+G D+    + PL+   P     K K  E       WGPP        E   S+EREW 
Sbjct: 1159 RRGDDSRPGPWRPLVK--PGGWREKEKAREE-----SWGPP-------RESRPSEEREWD 1204

Query: 167  QKLQGDASHETQEPESFSAWSDRLAREHAQKCQQ--QQREAEGSRRPPRAEGSSQSWRQQ 224
            ++ + D  ++ +E        +R       +  +  + R+  G RR P  E SS  WR  
Sbjct: 1205 REKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSS--WRDS 1262

Query: 225  EEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREE 269
                   R+  R + ++ R+ R RR      DR   P R+  REE
Sbjct: 1263 SRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRS-EREE 1306



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 38/134 (28%), Positives = 55/134 (41%), Gaps = 13/134 (9%)

Query: 155 EEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRA 214
           EE    ++ E R     +   E Q         +R  RE A++ ++++   E   R  + 
Sbjct: 792 EERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKL 851

Query: 215 EGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPT-----------R 263
           E   +  RQ+E E    RER R +E  L +S   R     GDR+ + T           R
Sbjct: 852 EEVERKKRQRELEIEE-RERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWR 910

Query: 264 AGPRE-EHPRGAGR 276
            GP E E  RG GR
Sbjct: 911 RGPPEKEWRRGEGR 924



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 37/197 (18%)

Query: 148 WDSAEEE-------EEDDASKEREWRQKLQGD---------ASHETQEPESFSAWSDRLA 191
           W+  EEE       E + A + +    ++  D         A+ ++   E    + +RLA
Sbjct: 725 WEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLA 784

Query: 192 REHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRL----FRERA-RAK-EEELRE- 244
            E   + ++++R+ +  RR        +  +++ EEQ L     RERA RAK EEELRE 
Sbjct: 785 EERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREY 844

Query: 245 -SRARRAQEALGDREPKPTRAGPRE---EHPRGAGRGSLWRFGDVPWPCPGGGDPEAM-- 298
             R ++ +E    +  +      RE   E  R  G  SL R  D  W   G  D E    
Sbjct: 845 QERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSR-KDSRW---GDRDSEGTWR 900

Query: 299 ----AAALVARGPPLEE 311
               A +   RGPP +E
Sbjct: 901 KGPEADSEWRRGPPEKE 917



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 32/130 (24%), Positives = 52/130 (40%), Gaps = 25/130 (19%)

Query: 143  GW--GPPWDSA--------EEEEEDDASKERE------WRQKLQGDASHE----TQEPES 182
            GW  GP  +S+        ++ + DD  +ER+       R+ L+ D          E E 
Sbjct: 1247 GWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREE 1306

Query: 183  FSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL 242
             S+W     R    +   +  E +  RR P    S    R ++ E+   +E+A  + E+ 
Sbjct: 1307 VSSW-----RRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKD 1361

Query: 243  RESRARRAQE 252
            RES  R   E
Sbjct: 1362 RESLRRTKNE 1371


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 33/117 (28%), Positives = 58/117 (49%), Gaps = 11/117 (9%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E E E +  +ERE  ++ + +   ET+         DR      ++ +Q + + E +R+ 
Sbjct: 308 ERERERNRKRERERERERERERQRETER--------DREKERERKRKRQTEMDRERNRQT 359

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
            R EG  Q+ R++E E+   R+ AR +EE  R+    R +E   +R+ +  R G RE
Sbjct: 360 GR-EGRRQAERERERERERDRQSAREREERERDRDRDRQKER--ERQTEKDRDGQRE 413



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/130 (22%), Positives = 58/130 (44%), Gaps = 12/130 (9%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E E +  +++ERE R++   D   + Q+        DR  +   +K ++++++ E  R  
Sbjct: 374 ERERDRQSAREREERER---DRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHP 271
            R          +E E++  RER R ++ + +  R R+      +  P+  R+G  +  P
Sbjct: 431 ERG---------REREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDP 481

Query: 272 RGAGRGSLWR 281
               RG  W+
Sbjct: 482 NRPTRGIRWK 491



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 15/141 (10%)

Query: 129 GIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSD 188
           G + +D +T GQ           E E + DA KERE     Q D   + Q   +     +
Sbjct: 135 GERGRDRQTDGQ----------RERERQRDAEKERE----RQTDRERQRQTERNRQKERE 180

Query: 189 RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR 248
           R      ++ +++QRE E       +E   +  R++E E    R+R   +E + R+ +  
Sbjct: 181 REKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD-RQRKTE 239

Query: 249 RAQEALGDREPKPTRAGPREE 269
           R +E   +RE    R   R++
Sbjct: 240 REREKQAERERASERETERDK 260



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 39/131 (29%), Positives = 58/131 (44%), Gaps = 14/131 (10%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E E E  A +ER   ++ + D   E +         DR  R+  QK +++Q + +  RR 
Sbjct: 239 EREREKQAERERASERETERDKERERERDR------DR-DRDRRQKERERQTDRKRQRRT 291

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR-RAQEALGDREPKPTRAGPRE-- 268
            R   + +   +Q E +R  RER R +E E    R R R +E   DRE +  R   R+  
Sbjct: 292 ERDRETERKRERQRERERE-RERNRKRERERERERERERQRETERDREKERERKRKRQTE 350

Query: 269 ---EHPRGAGR 276
              E  R  GR
Sbjct: 351 MDRERNRQTGR 361



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 29/117 (24%), Positives = 55/117 (47%), Gaps = 9/117 (7%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E E E +   ER+ +   + D   +T+      A  +R +    ++ ++++RE +  R  
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
            R        RQ+E E++  R+R R  E + RE+  +R ++   +RE +  R   RE
Sbjct: 273 DR--------RQKERERQTDRKRQRRTERD-RETERKRERQRERERERERNRKRERE 320



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 9/120 (7%)

Query: 149 DSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
           D+  ++ E +  KERE R++ +     ET          DR  +    + +Q+ RE E  
Sbjct: 48  DADGDDRERNRQKERE-RRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERE 106

Query: 209 RRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
           R+  R        RQ+E+E+   +ER R  E E    R R+     G RE +  R   +E
Sbjct: 107 RQTDRERD-----RQREKERNRQKERERETEREGERGRDRQTD---GQRERERQRDAEKE 158



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 27/109 (24%), Positives = 52/109 (47%), Gaps = 9/109 (8%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKC--QQQQREAEGSR 209
           + E+E +  KERE   + +G+   + Q          R A +  ++   +++QR+ E +R
Sbjct: 116 QREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR 175

Query: 210 RPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDRE 258
           +  R        R++  ++R  RER R KE +  +  + R +E   +RE
Sbjct: 176 QKERE-------REKNRQERRERERQREKENKTEDRHSERGRERERERE 217



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 27/117 (23%), Positives = 51/117 (43%), Gaps = 3/117 (2%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E+E E    +ER+ +++ + +   E +          R  +   Q+ +++QR+AE  R  
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERE- 160

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
              +   +  RQ E  ++  RER + ++E     R R  +    DR  +  R   RE
Sbjct: 161 --RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE 215



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 7/117 (5%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           +E + +D   ER   ++ + +   ET+         DR  +   ++ +Q +RE    R  
Sbjct: 197 KENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERET 256

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE 268
            R        +++E E+   R+R R ++E  R++  +R +    DRE +  R   RE
Sbjct: 257 ERD-------KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRE 306



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 14/129 (10%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQK--CQQQQREAEGSR 209
           + E E +  +ERE +++ + D   E +         DR       +   +Q +RE E  R
Sbjct: 316 KRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERER 375

Query: 210 RPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPRE- 268
                E   QS R++EE +R  R+R R KE E +  + R      G RE +  R   ++ 
Sbjct: 376 -----ERDRQSAREREERER-DRDRDRQKERERQTEKDRD-----GQRETEKQREREKDR 424

Query: 269 EHPRGAGRG 277
           E  RG  RG
Sbjct: 425 ESERGRERG 433



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 9/112 (8%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           + E + +  +ERE  +K + +   E +         DR      ++ +Q + + E +R+ 
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTR 263
            R EG  Q+ R+        RER R ++ +    R  R ++   DR+ +  R
Sbjct: 360 GR-EGRRQAERE--------RERERERDRQSAREREERERDRDRDRQKERER 402



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 12/120 (10%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E   E D  ++R+  ++ Q D   E +          R    + QK ++++ E EG R  
Sbjct: 80  ERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALG---DREPKPTRAGPRE 268
            R     Q+  Q+E E    R+R   KE E +  R R+ Q       +RE +  R   RE
Sbjct: 140 DR-----QTDGQRERE----RQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRE 190



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 15/137 (10%)

Query: 152 EEEEEDDASKEREWRQK-----------LQGDASHETQEPESFSAWSDRLAREHAQKCQQ 200
           E E E D  ++R+ RQK            + +   ET+         +R  RE  +K ++
Sbjct: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER-ERERNRK-RE 318

Query: 201 QQREAEGSR-RPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREP 259
           ++RE E  R R    E   +  R+++ +++   +R R ++   RE R +  +E   +RE 
Sbjct: 319 RERERERERERQRETERDREKERERKRKRQTEMDRERNRQTG-REGRRQAERERERERER 377

Query: 260 KPTRAGPREEHPRGAGR 276
               A  REE  R   R
Sbjct: 378 DRQSAREREERERDRDR 394



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 1/81 (1%)

Query: 196 QKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRA-QEAL 254
           ++ +Q++RE    +R    E   +  R++E+++   R+R R ++ +  + R R+  +E  
Sbjct: 55  ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114

Query: 255 GDREPKPTRAGPREEHPRGAG 275
             RE +  R   RE      G
Sbjct: 115 RQREKERNRQKERERETEREG 135


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 47/160 (29%), Positives = 68/160 (42%), Gaps = 24/160 (15%)

Query: 128 MGIKNKDGETPGQILGWGPPWDSAEEEEEDDASK----EREWRQKLQGDASH-ETQEPES 182
           M +KN      GQI    P  +   E+  D+ S     E E +++ + + +  E +E E 
Sbjct: 226 MSLKN------GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERER 279

Query: 183 FSAWSDRL---------AREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQ--EEEQRLF 231
             A  D+          A E A   ++++REAE   R    E  +   RQ+  EEE+R  
Sbjct: 280 IKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAA 339

Query: 232 RERARAKEEELR--ESRARRAQEALGDREPKPTRAGPREE 269
            ER R KEEE R  E R R  +E     E +       EE
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEE 379



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 18/128 (14%)

Query: 149 DSAEEEEEDDASKER-----EWRQKLQGD---------ASHETQEPESFSAWSDRLAREH 194
           +  EEE+++ A  ER     E R++++ +         A  E +E  +      R A E 
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314

Query: 195 AQKCQQQQREAEGSRRPPRAEGSSQSWRQQ--EEEQRLFRERARAKEEELRESRARRAQE 252
            +  ++++R AE  +R    E  +   RQ+  EEE+R   ER R KEEE R +  R  Q 
Sbjct: 315 ERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER--QR 372

Query: 253 ALGDREPK 260
           A  + E K
Sbjct: 373 ARAEEEEK 380



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 34/110 (30%), Positives = 55/110 (50%), Gaps = 13/110 (11%)

Query: 153 EEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPP 212
           E EE  A++ERE R         E +E E       R A E  +  ++++R AE  +R  
Sbjct: 296 EAEEKAAAQERERR---------EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIK 346

Query: 213 RAEGSSQSWRQQ--EEEQRLF--RERARAKEEELRESRARRAQEALGDRE 258
             E  +   RQ+  EEE+R    R+RARA+EEE  +   ++  + L +++
Sbjct: 347 EEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKK 396



 Score = 35.8 bits (81), Expect = 0.062
 Identities = 25/111 (22%), Positives = 48/111 (43%), Gaps = 1/111 (0%)

Query: 151 AEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRR 210
           AE   + +A K  E  ++ +G+   E  E          L  E  +K ++++R+      
Sbjct: 524 AEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE 583

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKP 261
             R +  +    ++EEE+R  +E    +  E  E R +  ++ L D + KP
Sbjct: 584 QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSD-DKKP 633



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 34/130 (26%), Positives = 53/130 (40%), Gaps = 23/130 (17%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           +EEE +  S E    +K+      E ++ E   A   RL  E  ++ + +Q +     R 
Sbjct: 240 QEEEREQGSDEISHHEKM------EEEDKERAEAERARLEAEERERIKAEQDKKIADERA 293

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEE---LRESRARRAQEALGDREPKPTRAGPR- 267
                     R + EE+   +ER R + EE   +RE   R A+E    +E +   A  R 
Sbjct: 294 ----------RIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQ 343

Query: 268 ---EEHPRGA 274
              EE  R A
Sbjct: 344 RIKEEEKRAA 353


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/124 (31%), Positives = 60/124 (48%), Gaps = 10/124 (8%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHA-QKCQQQQREAEGSRR 210
           E  E+    K+++  QK       +T++     A  +RLA E A +K   ++ E   +RR
Sbjct: 586 ERVEQMKEEKKKQIEQKF-AQIDEKTEK-----AKEERLAEEKAKKKAAAKKMEEVEARR 639

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEA--LGDREPKPTRAGPRE 268
               E     W QQEEE+R  +E  + K+EE +E R R+A EA  L ++  +  R   R 
Sbjct: 640 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE-RLRKAAEAKRLAEQREQERREQERR 698

Query: 269 EHPR 272
           E  R
Sbjct: 699 EQER 702



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 38/137 (27%), Positives = 66/137 (48%), Gaps = 14/137 (10%)

Query: 151 AEEEEEDDASKEREWRQKLQGDASH---------ETQEPESFSAWSDRLAREHAQKCQQQ 201
           A  ++E++A + R W Q+ + +  H         E QE    +A + RLA +  Q+ ++Q
Sbjct: 637 ARRKQEEEARRLR-WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 695

Query: 202 QREAEGSRRPPRAEGSSQSWRQQ--EEEQRLFRERARAKEEELRESRARRAQEALGDREP 259
           +R  +  R   R E   +   +Q  E+E+R  +ER +A+ E     +A R Q+    RE 
Sbjct: 696 ERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREL 755

Query: 260 KPTRAGPREEHPRGAGR 276
           +  +   +EE  R A R
Sbjct: 756 EEKK--KKEEQQRLAER 770



 Score = 36.2 bits (82), Expect = 0.048
 Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 2/106 (1%)

Query: 149 DSAEEEE--EDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAE 206
           + A+EE   E+ A K+   ++  + +A  + +E      W  +   E   +   Q+++ E
Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 670

Query: 207 GSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 252
              R  +A  + +   Q+E+E+R    R + + E+ R  + RR QE
Sbjct: 671 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 716



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 26/106 (24%), Positives = 53/106 (50%), Gaps = 2/106 (1%)

Query: 151 AEEEEEDDASKER-EWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSR 209
           AE+ E++   +ER E  ++ Q     E +E E   A  +R   +   + +++ +E E + 
Sbjct: 685 AEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 744

Query: 210 RPPRAEGSSQ-SWRQQEEEQRLFRERARAKEEELRESRARRAQEAL 254
           R  + +   +   ++++EEQ+   ER   +E+E +   A  A +AL
Sbjct: 745 RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 790



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 19/121 (15%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           ++EEE +  ++    ++L      E +E E          R   ++ +Q+++ AE  RR 
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR- 725

Query: 212 PRAEGSSQSWRQQEEEQRLFR----------ERARAKEE-------ELRESRARRAQEAL 254
            R +   Q+ R+ +E ++  R          E  + KEE       +L+E + ++A+EA 
Sbjct: 726 -REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 784

Query: 255 G 255
           G
Sbjct: 785 G 785


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/124 (31%), Positives = 60/124 (48%), Gaps = 10/124 (8%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHA-QKCQQQQREAEGSRR 210
           E  E+    K+++  QK       +T++     A  +RLA E A +K   ++ E   +RR
Sbjct: 582 ERVEQMKEEKKKQIEQKF-AQIDEKTEK-----AKEERLAEEKAKKKAAAKKMEEVEARR 635

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEA--LGDREPKPTRAGPRE 268
               E     W QQEEE+R  +E  + K+EE +E R R+A EA  L ++  +  R   R 
Sbjct: 636 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE-RLRKAAEAKRLAEQREQERREQERR 694

Query: 269 EHPR 272
           E  R
Sbjct: 695 EQER 698



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 38/137 (27%), Positives = 66/137 (48%), Gaps = 14/137 (10%)

Query: 151 AEEEEEDDASKEREWRQKLQGDASH---------ETQEPESFSAWSDRLAREHAQKCQQQ 201
           A  ++E++A + R W Q+ + +  H         E QE    +A + RLA +  Q+ ++Q
Sbjct: 633 ARRKQEEEARRLR-WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ 691

Query: 202 QREAEGSRRPPRAEGSSQSWRQQ--EEEQRLFRERARAKEEELRESRARRAQEALGDREP 259
           +R  +  R   R E   +   +Q  E+E+R  +ER +A+ E     +A R Q+    RE 
Sbjct: 692 ERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREL 751

Query: 260 KPTRAGPREEHPRGAGR 276
           +  +   +EE  R A R
Sbjct: 752 EEKK--KKEEQQRLAER 766



 Score = 36.2 bits (82), Expect = 0.048
 Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 2/106 (1%)

Query: 149 DSAEEEE--EDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAE 206
           + A+EE   E+ A K+   ++  + +A  + +E      W  +   E   +   Q+++ E
Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 666

Query: 207 GSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 252
              R  +A  + +   Q+E+E+R    R + + E+ R  + RR QE
Sbjct: 667 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 712



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 26/106 (24%), Positives = 53/106 (50%), Gaps = 2/106 (1%)

Query: 151 AEEEEEDDASKER-EWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSR 209
           AE+ E++   +ER E  ++ Q     E +E E   A  +R   +   + +++ +E E + 
Sbjct: 681 AEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 740

Query: 210 RPPRAEGSSQ-SWRQQEEEQRLFRERARAKEEELRESRARRAQEAL 254
           R  + +   +   ++++EEQ+   ER   +E+E +   A  A +AL
Sbjct: 741 RLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKAL 786



 Score = 32.7 bits (73), Expect = 0.53
 Identities = 28/121 (23%), Positives = 55/121 (45%), Gaps = 19/121 (15%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           ++EEE +  ++    ++L      E +E E          R   ++ +Q+++ AE  RR 
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR- 721

Query: 212 PRAEGSSQSWRQQEEEQRLFR----------ERARAKEE-------ELRESRARRAQEAL 254
            R +   Q+ R+ +E ++  R          E  + KEE       +L+E + ++A+EA 
Sbjct: 722 -REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 780

Query: 255 G 255
           G
Sbjct: 781 G 781


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 7/115 (6%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAW-SDRLAREHAQKCQQQQRE---AEG 207
           E+EE+    +++ WRQ+ +     E    +    W  +   RE  +K Q+Q+ E    E 
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL--RESRARRAQEALGDREPK 260
             R    +   + WR QE++ R   E+ R +EEE+  +E + R  +E + D+E K
Sbjct: 396 KIREQEEKRQEKMWR-QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK 449



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 6/111 (5%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E+EE+    +E+ WRQ+ +     E  + +    W     +E   + Q+++R+ +  R+ 
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR----QEEKIREQEEKRQEKMWRQE 412

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEEL--RESRARRAQEALGDREPK 260
            +     +  R+QEEE     E+ R  EE +  +E + R  +E + + E K
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 23/120 (19%), Positives = 56/120 (46%), Gaps = 7/120 (5%)

Query: 148 WDSAEE-EEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAE 206
           W   E+  E+++  +E+ WRQ+ +     E    +    W      E  ++ ++  ++ E
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ---EEKIRELEEMMQDQE 447

Query: 207 GSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE---LRESRARRAQEALGDREPKPTR 263
              R    +   +  + QE+E+++ R+  + +E+E    R+ +  + +E + ++E K  R
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 31/136 (22%), Positives = 65/136 (47%), Gaps = 20/136 (14%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQR-------- 203
           EE+ +++  K +E  +K+Q     + QE E  +   ++L ++  +  +Q+++        
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQ-EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512

Query: 204 -EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPT 262
            E E   +    +   Q  + +E+E RL+++  + +E+E+   R +  +E LG       
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV---RLQELEERLG------- 562

Query: 263 RAGPREEHPRGAGRGS 278
           + G + E   GAGR S
Sbjct: 563 KLGQKAELLGGAGRES 578



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 28/130 (21%), Positives = 60/130 (46%), Gaps = 13/130 (10%)

Query: 148 WDSAEEEEEDDASKEREWRQ--KLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQ--R 203
           W+   +++E     E+ WRQ  K+Q       ++        +++ R+  +  +Q++  R
Sbjct: 288 WNLLNQQQE-----EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342

Query: 204 EAEGS--RRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR--RAQEALGDREP 259
           E E    R+  +     +  R+QEE+     E+ R ++E+++E      R +E + ++E 
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402

Query: 260 KPTRAGPREE 269
           K      R+E
Sbjct: 403 KRQEKMWRQE 412


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 7/115 (6%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAW-SDRLAREHAQKCQQQQRE---AEG 207
           E+EE+    +++ WRQ+ +     E    +    W  +   RE  +K Q+Q+ E    E 
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEE 395

Query: 208 SRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL--RESRARRAQEALGDREPK 260
             R    +   + WR QE++ R   E+ R +EEE+  +E + R  +E + D+E K
Sbjct: 396 KIREQEEKRQEKMWR-QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEK 449



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 6/111 (5%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E+EE+    +E+ WRQ+ +     E  + +    W     +E   + Q+++R+ +  R+ 
Sbjct: 357 EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR----QEEKIREQEEKRQEKMWRQE 412

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEEL--RESRARRAQEALGDREPK 260
            +     +  R+QEEE     E+ R  EE +  +E + R  +E + + E K
Sbjct: 413 KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEK 463



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 23/120 (19%), Positives = 56/120 (46%), Gaps = 7/120 (5%)

Query: 148 WDSAEE-EEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAE 206
           W   E+  E+++  +E+ WRQ+ +     E    +    W      E  ++ ++  ++ E
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ---EEKIRELEEMMQDQE 447

Query: 207 GSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE---LRESRARRAQEALGDREPKPTR 263
              R    +   +  + QE+E+++ R+  + +E+E    R+ +  + +E + ++E K  R
Sbjct: 448 EKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWR 507



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 31/136 (22%), Positives = 65/136 (47%), Gaps = 20/136 (14%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQR-------- 203
           EE+ +++  K +E  +K+Q     + QE E  +   ++L ++  +  +Q+++        
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQ-EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKM 512

Query: 204 -EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPT 262
            E E   +    +   Q  + +E+E RL+++  + +E+E+   R +  +E LG       
Sbjct: 513 WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV---RLQELEERLG------- 562

Query: 263 RAGPREEHPRGAGRGS 278
           + G + E   GAGR S
Sbjct: 563 KLGQKAELLGGAGRES 578



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 28/130 (21%), Positives = 60/130 (46%), Gaps = 13/130 (10%)

Query: 148 WDSAEEEEEDDASKEREWRQ--KLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQ--R 203
           W+   +++E     E+ WRQ  K+Q       ++        +++ R+  +  +Q++  R
Sbjct: 288 WNLLNQQQE-----EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342

Query: 204 EAEGS--RRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR--RAQEALGDREP 259
           E E    R+  +     +  R+QEE+     E+ R ++E+++E      R +E + ++E 
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402

Query: 260 KPTRAGPREE 269
           K      R+E
Sbjct: 403 KRQEKMWRQE 412


>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform b [Homo sapiens]
          Length = 998

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 54/207 (26%), Positives = 82/207 (39%), Gaps = 21/207 (10%)

Query: 69  LHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAM 128
           LH A A+  +  L LL++ G +   QD  G T LHAAA  G          +L+     M
Sbjct: 221 LHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACS----ILAEALCDM 276

Query: 129 GIKNKDGETPGQILGWG-PPWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWS 187
            I+NK G+TP  +   G        +++++    E+E R KL     +   +   F    
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKE 336

Query: 188 DRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRA 247
             L  E   K Q+ + E          E SS S  ++E E         A E E  E  A
Sbjct: 337 KMLYEEETPKSQEMEEE--------NKESSSSSSEEEEGED-------EASESE-TEKEA 380

Query: 248 RRAQEALGDREPKPTRAGPREEHPRGA 274
            +  EA  +     +++   E+ P  A
Sbjct: 381 DKKPEAFVNHSNSESKSSITEQIPAPA 407



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/141 (26%), Positives = 62/141 (43%), Gaps = 14/141 (9%)

Query: 42  SAGRLVRAQALLQRHPGLD-VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDT 100
           S+G     + LL R   ++ V+      LH+AC   +   +  L+   A+   QD  G T
Sbjct: 67  SSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWT 126

Query: 101 ALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDAS 160
            LHAAA  G     ++F+       +++GI N +GE P          D AEE    D  
Sbjct: 127 PLHAAASCGYLNIAEYFI----NHGASVGIVNSEGEVPS---------DLAEEPAMKDLL 173

Query: 161 KEREWRQKLQGDASHETQEPE 181
            E+  +Q +  + S + +E +
Sbjct: 174 LEQVKKQGIDLEQSRKEEEQQ 194


>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform a [Homo sapiens]
          Length = 982

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 54/207 (26%), Positives = 82/207 (39%), Gaps = 21/207 (10%)

Query: 69  LHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAM 128
           LH A A+  +  L LL++ G +   QD  G T LHAAA  G          +L+     M
Sbjct: 221 LHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACS----ILAEALCDM 276

Query: 129 GIKNKDGETPGQILGWG-PPWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWS 187
            I+NK G+TP  +   G        +++++    E+E R KL     +   +   F    
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKE 336

Query: 188 DRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRA 247
             L  E   K Q+ + E          E SS S  ++E E         A E E  E  A
Sbjct: 337 KMLYEEETPKSQEMEEE--------NKESSSSSSEEEEGED-------EASESE-TEKEA 380

Query: 248 RRAQEALGDREPKPTRAGPREEHPRGA 274
            +  EA  +     +++   E+ P  A
Sbjct: 381 DKKPEAFVNHSNSESKSSITEQIPAPA 407



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/141 (26%), Positives = 62/141 (43%), Gaps = 14/141 (9%)

Query: 42  SAGRLVRAQALLQRHPGLD-VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDT 100
           S+G     + LL R   ++ V+      LH+AC   +   +  L+   A+   QD  G T
Sbjct: 67  SSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWT 126

Query: 101 ALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDAS 160
            LHAAA  G     ++F+       +++GI N +GE P          D AEE    D  
Sbjct: 127 PLHAAASCGYLNIAEYFI----NHGASVGIVNSEGEVPS---------DLAEEPAMKDLL 173

Query: 161 KEREWRQKLQGDASHETQEPE 181
            E+  +Q +  + S + +E +
Sbjct: 174 LEQVKKQGIDLEQSRKEEEQQ 194


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 27/124 (21%), Positives = 58/124 (46%)

Query: 154 EEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPR 213
           + E +  KER  R+K + +   E +          R  RE  ++ +++++E E  R+  R
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90

Query: 214 AEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRG 273
            +   +  +++++ +R  R R   K+++ R+ R R  ++    +  K  +   R+E  R 
Sbjct: 91  EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150

Query: 274 AGRG 277
             RG
Sbjct: 151 KERG 154



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 27/119 (22%), Positives = 60/119 (50%), Gaps = 1/119 (0%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLARE-HAQKCQQQQREAEGSRR 210
           +E + +   KE++ R+K +     E +  E      +R  +E   +K ++++RE +   R
Sbjct: 52  KERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGR 111

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREE 269
             R +   +  R++E +QR  R+R + ++++ R+ R R  +    +R+ K  +   RE+
Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREK 170



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 32/131 (24%), Positives = 61/131 (46%), Gaps = 14/131 (10%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQ--------KCQQQQR 203
           ++ ++ +  KERE ++K +     E +E E      ++  RE  Q        K ++++R
Sbjct: 64  KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123

Query: 204 EAEGSRRPPRAEGSSQSWRQQEEEQR------LFRERARAKEEELRESRARRAQEALGDR 257
           E E  +R  R     +  ++++E +R        R+R + K+EE  + R R  +E   +R
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183

Query: 258 EPKPTRAGPRE 268
           E K  R   +E
Sbjct: 184 ERKERRERKKE 194



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 18/112 (16%), Positives = 51/112 (45%), Gaps = 6/112 (5%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E +E +  +K+R  R++ +       +E +       R  +   +K ++++++ E +R+ 
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE 178

Query: 212 PRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTR 263
            + E      R+++E +   +ER + + ++    + R+       +  +P R
Sbjct: 179 RKKE------RERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLR 224


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 6/132 (4%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRP 211
           E +E ++  K ++  +K +G  S E +E E          +E  +K +++++E E   R 
Sbjct: 105 ENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK 164

Query: 212 PRAE---GSSQSWRQQEE-EQRLFRERARA--KEEELRESRARRAQEALGDREPKPTRAG 265
            R     G  +  R+++E ++R  RER R   K+E  R+ R  R +E     E K  R  
Sbjct: 165 KRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224

Query: 266 PREEHPRGAGRG 277
            R+ + R   RG
Sbjct: 225 DRQTNWREKERG 236



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 32/139 (23%), Positives = 62/139 (44%), Gaps = 15/139 (10%)

Query: 146 PPWDSAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDR-LAREHAQKCQQQQRE 204
           P W S   E E +    +E +++ + +   E +E E      ++   RE  +K ++ +R+
Sbjct: 32  PGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERK 91

Query: 205 AEGSRRPPRA------EGSSQSWRQQEEEQRLFR--------ERARAKEEELRESRARRA 250
            E   R  R       EG  +  R+++E++   R        ER   ++ E R+ R R+ 
Sbjct: 92  KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151

Query: 251 QEALGDREPKPTRAGPREE 269
           +E   +RE K  +   R++
Sbjct: 152 EEREKERERKERKKRERKQ 170



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 28/125 (22%), Positives = 59/125 (47%), Gaps = 13/125 (10%)

Query: 153 EEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPP 212
           ++EE +  K R  ++  +G+   + ++ E       R ++E  ++ ++++R+ E   R  
Sbjct: 91  KKEERERKKRRREKENKEGEEKEKRKKKEKKER--GRTSKEGKERERKEERKRE--ERKE 146

Query: 213 RAEGSSQSWRQQEEEQRLFRER---------ARAKEEELRESRARRAQEALGDREPKPTR 263
           R     +  +++E ++R  RER          + KE + R+ R R  +E   +RE K  R
Sbjct: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR 206

Query: 264 AGPRE 268
              +E
Sbjct: 207 ERKKE 211



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 2/90 (2%)

Query: 153 EEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAE--GSRR 210
           ++EE +  +ER+ R+K +     E +E        +R  RE  +K ++++RE +    R+
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERK 209

Query: 211 PPRAEGSSQSWRQQEEEQRLFRERARAKEE 240
             R +   +   +Q++ Q  +RE+ R K E
Sbjct: 210 KERKKKEERKKERQKDRQTNWREKERGKRE 239



 Score = 36.2 bits (82), Expect = 0.048
 Identities = 30/125 (24%), Positives = 61/125 (48%), Gaps = 9/125 (7%)

Query: 150 SAEEEEEDDASKEREWRQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSR 209
           +++E +E +  +ER+  ++ + +   E +E E      +R  RE  Q  ++++   E  R
Sbjct: 126 TSKEGKERERKEERKREERKERERKKEEREKERER--KERKKRERKQVGEKEEERKEKER 183

Query: 210 RPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREP--KPTRAGPR 267
           +  +    ++  R++E E++  RER   K+E  R+ +  R +E   DR+   +    G R
Sbjct: 184 KERKKRERNRKERKKERERKERRER---KKE--RKKKEERKKERQKDRQTNWREKERGKR 238

Query: 268 EEHPR 272
           E   R
Sbjct: 239 ERKER 243



 Score = 35.4 bits (80), Expect = 0.081
 Identities = 27/125 (21%), Positives = 57/125 (45%), Gaps = 7/125 (5%)

Query: 152 EEEEEDDASKEREWRQKLQGDASHETQ-EPESFSAWSDRLAREHAQKCQQQQRE------ 204
           ++E E +  KER  R+K + +   E + E        +R   E  +K +++++E      
Sbjct: 52  KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111

Query: 205 AEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRA 264
            E  ++  + E    S   +E E++  R+R   KE E ++    + +E    ++ +  + 
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171

Query: 265 GPREE 269
           G +EE
Sbjct: 172 GEKEE 176



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 17/98 (17%)

Query: 152 EEEEEDDASKEREWRQKLQ-GDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEG--- 207
           EE E++   KER+ R++ Q G+   E +E E      +R  RE  +K ++++RE +    
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKER----KERKKRERNRKERKKERERKERRE 207

Query: 208 ---------SRRPPRAEGSSQSWRQQEEEQRLFRERAR 236
                     R+  R +    +WR++E  +R  +ER +
Sbjct: 208 RKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,908,519
Number of Sequences: 37866
Number of extensions: 1007649
Number of successful extensions: 12673
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 351
Number of HSP's successfully gapped in prelim test: 633
Number of HSP's that attempted gapping in prelim test: 6875
Number of HSP's gapped (non-prelim): 4039
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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