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Search of human proteins with 222352173
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222352173 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 1 [Homo sapiens]
(381 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222352173 nuclear factor of kappa light polypeptide gene enha... 787 0.0
gi|222352175 nuclear factor of kappa light polypeptide gene enha... 745 0.0
gi|222352177 nuclear factor of kappa light polypeptide gene enha... 741 0.0
gi|222352179 nuclear factor of kappa light polypeptide gene enha... 699 0.0
gi|148746195 trichohyalin [Homo sapiens] 54 2e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 53 5e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 53 5e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 53 5e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 53 5e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 50 3e-06
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 50 4e-06
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 50 4e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 6e-06
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 49 8e-06
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 49 1e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 48 2e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 48 2e-05
gi|117320531 nuclear factor of kappa light polypeptide gene enha... 47 2e-05
gi|117320540 nuclear factor of kappa light polypeptide gene enha... 47 2e-05
gi|117320527 nuclear factor of kappa light polypeptide gene enha... 47 2e-05
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 47 3e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 5e-05
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 45 8e-05
gi|32484977 angiomotin like 2 [Homo sapiens] 45 8e-05
gi|119220598 apolipoprotein B48 receptor [Homo sapiens] 45 1e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 45 1e-04
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 45 1e-04
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 45 1e-04
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 45 1e-04
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 45 1e-04
>gi|222352173 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 1 [Homo
sapiens]
Length = 381
Score = 787 bits (2033), Expect = 0.0
Identities = 381/381 (100%), Positives = 381/381 (100%)
Query: 1 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD 60
MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
Sbjct: 1 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD 60
Query: 61 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL 120
VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
Sbjct: 61 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL 120
Query: 121 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV 180
LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV
Sbjct: 121 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV 180
Query: 181 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE 240
MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE
Sbjct: 181 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE 240
Query: 241 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV 300
EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
Sbjct: 241 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV 300
Query: 301 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG 360
PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
Sbjct: 301 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG 360
Query: 361 RVMGAVTALSQALNRHAEALK 381
RVMGAVTALSQALNRHAEALK
Sbjct: 361 RVMGAVTALSQALNRHAEALK 381
>gi|222352175 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 2 [Homo
sapiens]
Length = 366
Score = 745 bits (1924), Expect = 0.0
Identities = 366/381 (96%), Positives = 366/381 (96%), Gaps = 15/381 (3%)
Query: 1 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD 60
MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD
Sbjct: 1 MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLD 60
Query: 61 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL 120
VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL
Sbjct: 61 VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPL 120
Query: 121 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEV 180
LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQG
Sbjct: 121 LSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQG--------- 171
Query: 181 MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE 240
DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE
Sbjct: 172 ------DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE 225
Query: 241 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV 300
EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV
Sbjct: 226 EEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDV 285
Query: 301 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG 360
PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG
Sbjct: 286 PWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELG 345
Query: 361 RVMGAVTALSQALNRHAEALK 381
RVMGAVTALSQALNRHAEALK
Sbjct: 346 RVMGAVTALSQALNRHAEALK 366
>gi|222352177 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 3 [Homo
sapiens]
Length = 358
Score = 741 bits (1914), Expect = 0.0
Identities = 358/358 (100%), Positives = 358/358 (100%)
Query: 24 MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL 83
MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL
Sbjct: 1 MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL 60
Query: 84 LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG 143
LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG
Sbjct: 61 LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG 120
Query: 144 WGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSD 203
WGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSD
Sbjct: 121 WGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSD 180
Query: 204 RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR 263
RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR
Sbjct: 181 RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR 240
Query: 264 RAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPP 323
RAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPP
Sbjct: 241 RAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPP 300
Query: 324 LEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK 381
LEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK
Sbjct: 301 LEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK 358
>gi|222352179 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 4 [Homo
sapiens]
Length = 343
Score = 699 bits (1805), Expect = 0.0
Identities = 343/358 (95%), Positives = 343/358 (95%), Gaps = 15/358 (4%)
Query: 24 MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL 83
MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL
Sbjct: 1 MASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCL 60
Query: 84 LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG 143
LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG
Sbjct: 61 LLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILG 120
Query: 144 WGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSD 203
WGPPWDSAEEEEEDDASKEREWRQKLQG DASHETQEPESFSAWSD
Sbjct: 121 WGPPWDSAEEEEEDDASKEREWRQKLQG---------------DASHETQEPESFSAWSD 165
Query: 204 RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR 263
RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR
Sbjct: 166 RLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR 225
Query: 264 RAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPP 323
RAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPP
Sbjct: 226 RAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPP 285
Query: 324 LEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK 381
LEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK
Sbjct: 286 LEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK 343
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 54.3 bits (129), Expect = 2e-07
Identities = 40/127 (31%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
D + EEE + ++ +Q+L+ + E+E +E + E + E QE +L RE
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE-----QQLRRE 510
Query: 209 HAQKCQQQ-QREAEGSRRPPRAEGSSQSWRQQEE--EQRLFRERARAKEEELRESRARRA 265
++ +Q+ +R+ E R R Q R+QEE EQ L RE + E+E RE R +R
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 266 QEALGDR 272
QE D+
Sbjct: 571 QEERRDQ 577
Score = 53.9 bits (128), Expect = 2e-07
Identities = 39/141 (27%), Positives = 70/141 (49%), Gaps = 3/141 (2%)
Query: 147 PWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLA 206
P E +EE++ ++ E RQ+L+ E ++E Q+ QE E +R
Sbjct: 265 PQRQRELQEEEEQLRKLE-RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER-- 321
Query: 207 REHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQ 266
RE ++ +QQ+ E R + E Q R+++EE+R ++ R +EEE RE + RR Q
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 267 EALGDREPKPTRAGPREEHPR 287
+ +++ + + RE+ R
Sbjct: 382 QLRREQQLRREQQLRREQQLR 402
Score = 48.1 bits (113), Expect = 1e-05
Identities = 33/117 (28%), Positives = 61/117 (52%), Gaps = 4/117 (3%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
+ EEE +ER Q+L+ E E+ +++ R E + + + E RL RE +
Sbjct: 551 KREEEKRLEQERR-EQRLKREQEERRDQLLKR-EEERRQQRLKREQEERLEQRLKREEVE 608
Query: 212 KCQQQQR-EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 267
+ +Q++R E R P E Q + +E+E+R +++ R +++E RE R +R +E
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERR-QQQLRREQQERREQRLKREEE 664
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 12/128 (9%)
Query: 148 WDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAR 207
W E + K +E + Q EL++E +++ + E QE E RL R
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQ---QQQRLRR 302
Query: 208 EHA--------QKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRE 259
E ++ QQ++R + RR + E Q R+++EE+R + R R +EEE RE
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR-REQEEERRE 361
Query: 260 SRARRAQE 267
+ RR QE
Sbjct: 362 QQLRREQE 369
Score = 47.0 bits (110), Expect = 3e-05
Identities = 44/152 (28%), Positives = 73/152 (48%), Gaps = 21/152 (13%)
Query: 152 EEEEEDDASKEREWR-QKLQGELEDEWQEVMGRFEGDASHE----------TQEPESFSA 200
+EEE + E+E R Q+L+ E ++E ++ + R E HE QE E
Sbjct: 429 QEEERHEQKHEQERREQRLKRE-QEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 201 WSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRL-----FRERARAKEE 255
W L E ++ +QQ+R + RR + E Q ++QEEE+RL ++ R ++E
Sbjct: 488 W---LKLEEEERREQQERREQQLRR-EQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 256 ELRESRARRAQEALGDREPKPTRAGPREEHPR 287
E RE +R +E ++E + R +E R
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERR 575
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/141 (26%), Positives = 73/141 (51%), Gaps = 12/141 (8%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
EE+++ +E++ R+K + E ++ +E R E E QE +L RE +
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEE---RREQQERREQQEERR----EQQLRREQEE 345
Query: 212 KCQQQ-QREAEGSRRPPRAEGSSQSWRQQEE---EQRLFRERARAKEEEL-RESRARRAQ 266
+ +QQ +RE E RR + + R++++ EQ+L RE+ +E++L RE + RR Q
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 267 EALGDREPKPTRAGPREEHPR 287
+ +++ + + RE+ R
Sbjct: 406 QLRREQQLRREQQLRREQQLR 426
Score = 46.2 bits (108), Expect = 5e-05
Identities = 44/148 (29%), Positives = 70/148 (47%), Gaps = 23/148 (15%)
Query: 149 DSAEEEEEDDASKEREW-----RQKL-------QGELEDEWQEVMGRFEGDASHETQEPE 196
D +EEE+ ++RE +KL Q EL++E +++ + E QE E
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Query: 197 SFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE 256
RL RE QQ +R+ E RR + E Q R++++E+R ++ R ++EE
Sbjct: 295 Q---QQQRLRRE-----QQLRRKQEEERREQQEERREQQERREQQEERR-EQQLRREQEE 345
Query: 257 LRESRARRAQEALGDREPKPTRAGPREE 284
RE + RR QE +R + R EE
Sbjct: 346 RREQQLRREQEE--ERREQQLRREQEEE 371
Score = 45.8 bits (107), Expect = 6e-05
Identities = 40/132 (30%), Positives = 61/132 (46%), Gaps = 13/132 (9%)
Query: 149 DSAEEEEEDDASKEREWR--QKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLA 206
+ EE E +E+E R Q+L+ E E+E +E R E + Q+ +L
Sbjct: 329 EQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR----EQQLR 384
Query: 207 REHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQE--EEQRLFRERARAK-----EEELRE 259
RE + +QQ R + RR + Q R+Q+ EQ+L RE+ + E+E RE
Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
Query: 260 SRARRAQEALGD 271
R +R QE D
Sbjct: 445 QRLKREQEERRD 456
Score = 45.4 bits (106), Expect = 8e-05
Identities = 43/157 (27%), Positives = 71/157 (45%), Gaps = 27/157 (17%)
Query: 149 DSAEEEEEDDASKEREWRQ--------KLQGELEDEWQEVMG-----RFEGDASHETQEP 195
D ++EEE +ERE R+ + + EL+ E ++++G R + + ++
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Query: 196 ESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEE 255
E ++L RE +K ++Q+RE R R E QQEEEQ L ER + + +
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERE-----RQCREEEE----LQQEEEQLLREEREKRRRQ 1134
Query: 256 EL-----RESRARRAQEALGDREPKPTRAGPREEHPR 287
EL E ++ +E L EP+ R E R
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171
Score = 45.4 bits (106), Expect = 8e-05
Identities = 32/121 (26%), Positives = 62/121 (51%), Gaps = 6/121 (4%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMG-----RFEGDASHETQEPESFSAWSDRLAR 207
EE E +ERE + + + EL+ E ++++ R + + +E E ++L R
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 208 EHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL-RESRARRAQ 266
E +K ++Q+ E + + Q R+++E++R RER +EEEL R+ R +R +
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 267 E 267
+
Sbjct: 1216 D 1216
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/138 (29%), Positives = 58/138 (42%), Gaps = 16/138 (11%)
Query: 152 EEEEEDDASKEREWR---QKLQGELEDEWQEVMGRFEGDASHETQ-------EPESFSAW 201
EE E +E+E Q+L+ E E+E +E R E E Q E
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR 403
Query: 202 SDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRER------ARAKEE 255
+L RE + +QQ R + RR E Q Q+ EQRL RE+ + +EE
Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEE 463
Query: 256 ELRESRARRAQEALGDRE 273
R + RR Q+ D+E
Sbjct: 464 TERHEQERRKQQLKRDQE 481
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/135 (27%), Positives = 66/135 (48%), Gaps = 7/135 (5%)
Query: 154 EEEDDASKEREWRQKLQGELEDEWQ--EVMGRFEGDA--SHETQEPESFSAWSDRLAREH 209
EE+ +ER+ R Q E E EW+ E + R E + E Q ++L +
Sbjct: 224 EEKQQQRRERQDRV-FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 210 AQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEAL 269
Q+ +++++E E ++ R E Q R+QEEE+R +E R ++E + RR Q+
Sbjct: 283 RQELRRERQEEEQQQQRLRRE--QQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Query: 270 GDREPKPTRAGPREE 284
++E + + RE+
Sbjct: 341 REQEERREQQLRREQ 355
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 10/144 (6%)
Query: 148 WDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDA-------SHETQEPESFSA 200
W EEEE + + RE Q+L+ E E+ ++ + R E + S + E
Sbjct: 488 WLKLEEEERREQQERRE--QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545
Query: 201 WSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRES 260
L RE ++ +Q++RE R ++ +QRL RE+ E+ L+
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605
Query: 261 RARRAQEALGDREPKPTRAGPREE 284
R ++ RE + R P EE
Sbjct: 606 EVERLEQE-ERREQRLKREEPEEE 628
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 21/139 (15%)
Query: 152 EEEEEDDASKEREWR--QKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREH 209
+EE D K E R Q+L+ E E+ ++ + R E + + + E RL RE
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQ------RLKREE 624
Query: 210 AQ--------KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERAR-----AKEEE 256
+ K ++Q+ + R + E Q +++EEE+RL + R +E+E
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 257 LRESRARRAQEALGDREPK 275
L E +A+E + R PK
Sbjct: 685 LAEEEQEQARERIKSRIPK 703
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 6/138 (4%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMG-----RFEGDASHETQEPESFSAWSDRLAR 207
EE E +ERE + + + EL+ E ++++G R + + ++ E ++L R
Sbjct: 1036 EEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR 1095
Query: 208 EHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFR-ERARAKEEELRESRARRAQ 266
E +K ++Q+RE + + Q R++ E++R ER +EEE+++ + +
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 267 EALGDREPKPTRAGPREE 284
E R + REE
Sbjct: 1156 EEPEKRRRQELERQYREE 1173
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/145 (27%), Positives = 66/145 (45%), Gaps = 19/145 (13%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMG-----RFEGDASHETQEPESFSAWSDRLAR 207
EE E +ERE + + + EL+ E ++++ R + + ++ + ++L R
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035
Query: 208 EHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL-----RESRA 262
E +K + Q+RE R R E QQEEEQ L ER + +EL +E
Sbjct: 1036 EEREKRRLQERE-----RQYREEEE----LQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Query: 263 RRAQEALGDREPKPTRAGPREEHPR 287
++ +E L EP+ R RE R
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCR 1111
Score = 42.7 bits (99), Expect = 5e-04
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 4/120 (3%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
EEE + + RE +++ + + E Q++ E + + + +L RE +
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 212 KCQQQQ-REAEGSRRPPRAEGSSQSWRQQE--EEQRLFRERARAKEEEL-RESRARRAQE 267
+ ++QQ R + RR + Q R+Q+ EQ+L RE+ +E++L RE + RR QE
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Score = 42.7 bits (99), Expect = 5e-04
Identities = 35/144 (24%), Positives = 68/144 (47%), Gaps = 11/144 (7%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
D +E++E S+E+ QK + +LE+E + + + Q + +L +E
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE-----QQLLQE 908
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL-----RESRAR 263
++ Q+++RE R+ + + QQEEEQ L ER + + +E ++ + +
Sbjct: 909 EEEELQREEREKR-RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Query: 264 RAQEALGDREPKPTRAGPREEHPR 287
+ +E L EP+ R RE+ R
Sbjct: 968 QKEEQLLGEEPEKRRRQEREKKYR 991
Score = 42.7 bits (99), Expect = 5e-04
Identities = 30/121 (24%), Positives = 62/121 (51%), Gaps = 11/121 (9%)
Query: 156 EDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQ 215
++ KE++ Q+ + EL+ E +E R E + + +E E ++L RE +K ++
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY--REEEQLQQEEEQLLREEREKRRR 953
Query: 216 QQREAEGSR------RPPRAEGSSQSWRQQEEEQRLFRERARAKEEE---LRESRARRAQ 266
Q+RE + + + + G R+++E ++ +RE ++EE LRE R +R +
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 267 E 267
+
Sbjct: 1014 Q 1014
Score = 42.4 bits (98), Expect = 7e-04
Identities = 39/136 (28%), Positives = 56/136 (41%), Gaps = 15/136 (11%)
Query: 152 EEEEEDDASKEREWRQKLQGEL---EDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
EE+ E E+ RQ+ EL EWQE E E + E
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQE--------REERRAEEEQLQSCKGHETEE 203
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEA 268
+ Q ++RE RR R E Q ++E + R+F+E KE RE+ R+ +E
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQ---RRERQDRVFQEE-EEKEWRKRETVLRKEEEK 259
Query: 269 LGDREPKPTRAGPREE 284
L + EP+ R EE
Sbjct: 260 LQEEEPQRQRELQEEE 275
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/142 (25%), Positives = 68/142 (47%), Gaps = 23/142 (16%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGE--------LEDEWQEVMG-----RFEGDASHETQEP 195
+ ++EEE +ERE R++ + E L+ + ++++G R + + +E
Sbjct: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE 993
Query: 196 ESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRL-FRERARAKE 254
E ++L RE +K ++Q+ E + ++ + Q R++ E++RL RER +E
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 255 EELR---------ESRARRAQE 267
EEL+ E RR QE
Sbjct: 1054 EELQQEEEQLLGEERETRRRQE 1075
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 9/118 (7%)
Query: 156 EDDASKEREWR--QKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKC 213
E +E++ R Q+L+ E E+E E E +E E W L RE +
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW---LKREEETER 466
Query: 214 QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRER----ARAKEEELRESRARRAQE 267
+Q+R + +R E + + +EEE+R +ER R ++EE RE R +R +E
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/139 (30%), Positives = 65/139 (46%), Gaps = 14/139 (10%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQ---EVMGRFEGDASHETQEPESFSAWSDRLARE 208
+EE + K +E ++LQ L E Q E R E E ++ RL RE
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEE--EQRLFRERA-RAKEEELRESRARRA 265
++ + Q + E RR R + R+QEE EQRL RE R ++EE RE R +R
Sbjct: 571 QEER-RDQLLKREEERRQQRLK------REQEERLEQRLKREEVERLEQEERREQRLKR- 622
Query: 266 QEALGDREPKPTRAGPREE 284
+E +R + ++ +EE
Sbjct: 623 EEPEEERRQQLLKSEEQEE 641
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/144 (28%), Positives = 64/144 (44%), Gaps = 34/144 (23%)
Query: 154 EEEDDASKER------EWRQKLQGELEDEWQEVMGR---FEGDASHETQEP-----ESFS 199
EEE + ++ER +W+ +L+ E + +V R EG + QE ES
Sbjct: 687 EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Query: 200 AWSDRLAREHAQKCQQQQR-------EAEG---------SRRPPRAEGSSQSWRQQEEEQ 243
W + R H Q+ +++QR +AE S RPP E + R +E +Q
Sbjct: 747 QWQEE-ERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ 805
Query: 244 RLFRERARAKEEELRESRARRAQE 267
RE+ EEE +E R R+ +E
Sbjct: 806 ---REQRFLPEEEEKEQRRRQRRE 826
Score = 40.0 bits (92), Expect = 0.003
Identities = 29/129 (22%), Positives = 60/129 (46%), Gaps = 5/129 (3%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
+ ++EEE +ERE R++ + E + ++ + + E E +E +R RE
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE-RERQYRE 1052
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQ----QEEEQRLFRERARAKEEELRESRARR 264
+ Q++++ R R + + +R+ Q+EE++L RE + + RE + R
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
Query: 265 AQEALGDRE 273
+E + E
Sbjct: 1113 EEELQQEEE 1121
Score = 39.3 bits (90), Expect = 0.006
Identities = 33/140 (23%), Positives = 67/140 (47%), Gaps = 18/140 (12%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
+EEED +++E R+ + + +W+ + E ++ + ++ +E +K
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQL--------EEERKRRRHTLYAKPALQEQLRK 901
Query: 213 CQQQ-QREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE---LRESRARRAQEA 268
QQ Q E E +R R + R+++E++R +RE + ++EE LRE R +R ++
Sbjct: 902 EQQLLQEEEEELQREEREK------RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Query: 269 LGDREPKPTRAGPREEHPRG 288
+ K + +EE G
Sbjct: 956 RERQYRKDKKLQQKEEQLLG 975
Score = 38.5 bits (88), Expect = 0.010
Identities = 64/229 (27%), Positives = 81/229 (35%), Gaps = 70/229 (30%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
+ EEE K E ++ Q +L E QE R E E +E RL RE
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQE---RREQRLKREEEEERL----EQRLKRE 675
Query: 209 H---------AQKCQQQQREAEGSR---------------------RPPRAEGSSQSWRQ 238
H A++ Q+Q RE SR RP + EG Q RQ
Sbjct: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG--QRRRQ 733
Query: 239 QEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFG 298
++EE+R RE +EE RA R Q+ EE R
Sbjct: 734 EQEEKRRRRESELQWQEE---ERAHRQQQ--------------EEEQRR----------- 765
Query: 299 DVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFL 347
D W E L AR PPL EQ R LR ++ + RFL
Sbjct: 766 DFTWQWQAEEKSERGRQRLSAR-PPLREQ--RERQLRAEERQQREQRFL 811
Score = 38.5 bits (88), Expect = 0.010
Identities = 37/146 (25%), Positives = 63/146 (43%), Gaps = 30/146 (20%)
Query: 152 EEEEEDDASKEREWRQK-----LQGELEDEWQEVMGRFEGDASHETQ------EPESFSA 200
E++E D + R W+Q+ + +LE E Q+ R + + E Q E +
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 201 WSDRLAREHAQKCQQQQ------REAEGSRRPPRAEGSSQSWRQQEEEQRLFRE------ 248
+DR RE Q Q+++ +E + R Q + EEEQRL R+
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF 1392
Query: 249 -------RARAKEEELRESRARRAQE 267
R + +E++LR+ R R+ +E
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRKFRE 1418
Score = 38.5 bits (88), Expect = 0.010
Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 14/130 (10%)
Query: 153 EEEEDDASKEREWR-----QKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAR 207
EEE+ +ERE + Q+L+ E +++E E E +E + DR
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFRE-----EEQLLQEREEQQLHRQERDRKFL 1488
Query: 208 EHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAK--EEELRESRARRA 265
E Q+ ++Q+R+ + + R++ + + EEEQ+L R++ + K +EE + R R
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKF--LEEEQQLHRQQRQRKFLQEEQQLRRQERG 1546
Query: 266 QEALGDREPK 275
Q+ DR+ K
Sbjct: 1547 QQRRQDRDRK 1556
Score = 37.4 bits (85), Expect = 0.023
Identities = 43/142 (30%), Positives = 60/142 (42%), Gaps = 31/142 (21%)
Query: 162 EREWRQKLQGE---LEDEWQEV-MGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQ 217
+ E R + G+ L+D QE RFE +EP + QK Q+Q+
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEP----------GQRRRQKRQEQE 145
Query: 218 RE-AEGSRRPPRAEGSSQS---------WRQQEEEQRLFRERARAKEEELRESRARRA-- 265
RE AEG + + E Q WRQ++E Q RE RA+EE+L+ +
Sbjct: 146 RELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQE--REERRAEEEQLQSCKGHETEE 203
Query: 266 ---QEALGDREPKPTRAGPREE 284
+E L RE R REE
Sbjct: 204 FPDEEQLRRRELLELRRKGREE 225
Score = 37.4 bits (85), Expect = 0.023
Identities = 52/221 (23%), Positives = 89/221 (40%), Gaps = 15/221 (6%)
Query: 154 EEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPE--------SFSAWSDRL 205
+E D +E E R + QG E ++ + R E + +E + DR
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 206 AREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRA 265
RE Q+ +Q+R+ + + + + EEEQ+L +ER R EE + + R
Sbjct: 1416 FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREE 1475
Query: 266 QEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGG--DPEAMAAALVARGPP 323
Q+ R+ + + E+ R R +R ++ P + E +
Sbjct: 1476 QQL--HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Query: 324 LEEQGALRRYLRVQQVRWHPDRFL---QRFRSQIETWELGR 361
L+E+ LRR R QQ R DR ++ R + E +L R
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR 1574
Score = 37.0 bits (84), Expect = 0.030
Identities = 28/131 (21%), Positives = 62/131 (47%), Gaps = 9/131 (6%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEW---QEVMGRFEGDASHETQEPESFSAWSDRLARE 208
E E+ +ER++R++ Q + E+E +E R + + ++ + ++L E
Sbjct: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE 976
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEE------QRLFRERARAKEEELRESRA 262
+K ++Q+RE + + Q R++ E+ +R +R++ ++EE + R
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 263 RRAQEALGDRE 273
R + L +RE
Sbjct: 1037 EREKRRLQERE 1047
Score = 37.0 bits (84), Expect = 0.030
Identities = 48/207 (23%), Positives = 83/207 (40%), Gaps = 46/207 (22%)
Query: 154 EEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKC 213
EEE +++ R+ LQ E + QE + D + +E E R RE Q+
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQL-----RQEREE-QQL 1572
Query: 214 QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDRE 273
+Q+R+ + + Q + E+EQ+L R+ + + + R+ + R ++ L +RE
Sbjct: 1573 SRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQERE 1632
Query: 274 PKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRY 333
+ R+E R +F LEE+ LRR
Sbjct: 1633 EQQLH---RQERDR--------KF--------------------------LEEEPQLRRQ 1655
Query: 334 LRVQQVRWHPDRFLQRFRSQIETWELG 360
R QQ+R DR +FR + + + G
Sbjct: 1656 EREQQLRHDRDR---KFREEEQLLQEG 1679
Score = 36.6 bits (83), Expect = 0.039
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
+ ++EEE +E E R++ + E + +E + + E E +E L R+
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR----RQELERQ 1139
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE--LRESRARRAQ 266
+ ++ + QQ E + R P R+QE E++ E +EEE LRE + +R Q
Sbjct: 1140 YREEEEVQQEEEQLLREEPEKR------RRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 267 E 267
E
Sbjct: 1194 E 1194
Score = 36.6 bits (83), Expect = 0.039
Identities = 32/145 (22%), Positives = 61/145 (42%), Gaps = 17/145 (11%)
Query: 144 WGPPWDSAEEEEED--DASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAW 201
W P ++A + + + ++RQ +L D + + D H E +
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR------QSQQDLQHLLGEQQ----- 1275
Query: 202 SDRLAREHAQKCQQQQR---EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELR 258
+R + ++ QQ+ R E E R + E + + QEE+Q L ER + +
Sbjct: 1276 -ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 259 ESRARRAQEALGDREPKPTRAGPRE 283
+ + R ++ L +RE +P R R+
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERD 1359
Score = 36.6 bits (83), Expect = 0.039
Identities = 40/146 (27%), Positives = 66/146 (45%), Gaps = 18/146 (12%)
Query: 155 EEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSD---RLAREHAQ 211
EE+ +ERE +Q E + +++E E E +E + D R E Q
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFRE-----EEQLRQEREEQQLRPQQRDGKYRWEEEQLQ 1829
Query: 212 KCQQQQREAEGSRRPPRAEGS-SQSWRQQEEEQRLFRE----RARAKEEELRESRARRAQ 266
+Q+QR + R RAE + + + EEQ L++E R + +E +LRE RR Q
Sbjct: 1830 LEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889
Query: 267 EALGDREPKPTRAGP-REEHPRGAGR 291
+ E + + G + + +G GR
Sbjct: 1890 K----EEQRHRQVGEIKSQEGKGHGR 1911
Score = 36.2 bits (82), Expect = 0.050
Identities = 34/147 (23%), Positives = 67/147 (45%), Gaps = 12/147 (8%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGR-FEGDASHETQEPES-FSAWSDRLAREHA 210
+EE+ + E R+K + E + + +E R F+ + E ++ E+ ++L E
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 211 QKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRE----------RARAKEEELRES 260
Q+ ++ Q E E R+ R E + +++++QRL RE R +EE +
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 261 RARRAQEALGDREPKPTRAGPREEHPR 287
R QE +++ + + RE+ R
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLR 352
Score = 36.2 bits (82), Expect = 0.050
Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 29/161 (18%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQ-------EVMGRFEGDASHETQEPESFSAW 201
+ EE E +E++ R++ Q E + + E R E E Q
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 202 SDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEE-QRLFRER----------- 249
++ H QK +Q++RE +R R + + W ++EEE +R +ER
Sbjct: 427 REQEEERHEQKHEQERRE----QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482
Query: 250 ------ARAKEEELRESRARRAQEALGDREPKPTRAGPREE 284
+ +EEE RE + RR Q+ ++E + + R+E
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523
Score = 36.2 bits (82), Expect = 0.050
Identities = 40/135 (29%), Positives = 57/135 (42%), Gaps = 16/135 (11%)
Query: 146 PPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDAS--------HETQEPES 197
P + E EE+ +A + Q+ + L +E +E R E D E +E
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353
Query: 198 FSAWSDRLAREHAQKCQQQQR----EAEGSRRPPRAEG---SSQSWRQQEEEQRLFRERA 250
DR RE + Q+Q R E + RR R Q R QE EQ+L ++R
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRD 1413
Query: 251 RA-KEEELRESRARR 264
R +EEE + SR R
Sbjct: 1414 RKFREEEQQLSRQER 1428
Score = 35.8 bits (81), Expect = 0.066
Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 7/94 (7%)
Query: 210 AQKCQQQQREAEGSRRPPRAEGSSQSW----RQQEEEQRLFRERARAKEEELRESRARRA 265
AQ C +A G RA + R+QEE+QR F R R EEE + R ++
Sbjct: 82 AQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKR 141
Query: 266 QE---ALGDREPKPTRAGPREEHPRGAGRGSLWR 296
QE L + E + + E+ R LWR
Sbjct: 142 QEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
Score = 35.0 bits (79), Expect = 0.11
Identities = 35/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWS----DRLARE 208
+EEE+ + Q+L+ E E+ ++++ R E + + + D+L +
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEE--EQRLFRERARAKEEELR-------E 259
++ QQ+ + + R R + +QEE EQRL RE EEE R E
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEP---EEERRQQLLKSEE 638
Query: 260 SRARRAQEALGDREPKPTRAGPREE 284
RR Q+ +++ + + REE
Sbjct: 639 QEERRQQQLRREQQERREQRLKREE 663
Score = 35.0 bits (79), Expect = 0.11
Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 12/129 (9%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
EEE +E E R+ + + E + GR A +E +L E Q
Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE-----RQLRAEERQ 804
Query: 212 KCQQQ---QREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE----LRESRARR 264
+ +Q+ + E + RR R E + +EEEQ RERA+ +EE + RR
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 265 AQEALGDRE 273
+QE D++
Sbjct: 865 SQEQRRDQK 873
Score = 35.0 bits (79), Expect = 0.11
Identities = 32/134 (23%), Positives = 61/134 (45%), Gaps = 9/134 (6%)
Query: 155 EEDDASKEREWRQKLQGE-----LEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREH 209
EE+ +ERE +Q + E LE+E Q + R E D QE S +R E
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQ--LRRQERDRKFREQELRSQEP--ERKFLEE 1520
Query: 210 AQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEAL 269
Q+ +QQR+ + + + + +++++ R FRE + ++E + +R+ ++
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 270 GDREPKPTRAGPRE 283
E + R +E
Sbjct: 1581 FRLEEQKVRRQEQE 1594
Score = 34.3 bits (77), Expect = 0.19
Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 20/148 (13%)
Query: 155 EEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQ 214
EE+ + +E Q+L+ + + +++E E E +E + DR RE Q+ +
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFRE-----EEQLLQEGEEQQLRRQERDRKFREEEQQLR 1701
Query: 215 QQQREA-----------EGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELR----E 259
+Q+RE + R R E + +QE+ +R R R +EE+LR E
Sbjct: 1702 RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE 1761
Query: 260 SRARRAQEALGDREPKPTRAGPREEHPR 287
+ RR + RE + R E+ R
Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQQLR 1789
Score = 33.9 bits (76), Expect = 0.25
Identities = 26/110 (23%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
+ ++EEE +ERE R++ ELE +++E + + +EPE
Sbjct: 1114 EELQQEEEQLLREEREKRRRQ--ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELR 258
++ QQ++ + + R + + +R++EE QR R++ R ++E+ R
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQ-RYRDEDQR 1220
Score = 33.9 bits (76), Expect = 0.25
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 6/139 (4%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
++ + +E++ R++ +G+ + ++ R E E +E + DR R Q
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 212 KCQQQQREA---EGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEA 268
K ++Q++E E ++ R EG Q ++E R FRE + +E + R+ ++
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQEGQQQL---RQERDRKFREDEQLLQEREEQQLHRQERDR 1643
Query: 269 LGDREPKPTRAGPREEHPR 287
E R RE+ R
Sbjct: 1644 KFLEEEPQLRRQEREQQLR 1662
Score = 33.9 bits (76), Expect = 0.25
Identities = 29/143 (20%), Positives = 57/143 (39%), Gaps = 13/143 (9%)
Query: 152 EEEEEDDASKEREWRQKLQGE-----------LEDEWQEVMGRFEGDASHETQEPESFSA 200
E EE+ + +ER+ + +L+ + +EDE Q + R EG + F
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ--LRRQEGQQQLRQERDRKFRE 1623
Query: 201 WSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRES 260
L Q+ +Q+R+ + P+ + + + + R FRE + +E +
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Query: 261 RARRAQEALGDREPKPTRAGPRE 283
R+ ++ E + R RE
Sbjct: 1684 LRRQERDRKFREEEQQLRRQERE 1706
Score = 33.9 bits (76), Expect = 0.25
Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 6/114 (5%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
EEE+ +ERE R+ LQ E + QE+ +F + + + +R + ++
Sbjct: 1695 EEEQQLRRQERE-RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753
Query: 213 CQQQQREAEGSRRPPRAE--GSSQSWRQQEEEQRLFRERARAK---EEELRESR 261
+ +RE + RR R + RQ+ EEQ+L + + K EE+LR+ R
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807
Score = 33.9 bits (76), Expect = 0.25
Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 22/144 (15%)
Query: 152 EEEEEDDASKEREWRQK--LQGELEDEWQEVMGRFEGDASHETQEPESFSAW-----SDR 204
EE++ ER++R++ L+ E E E R+ E PE DR
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 205 LAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAK----------- 253
RE Q Q+++ + S+ R + RQ+ EEQ+L ++ K
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 254 --EEELRESRAR--RAQEALGDRE 273
E+ LR+ R R RA+E +E
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQE 1855
Score = 33.5 bits (75), Expect = 0.33
Identities = 34/140 (24%), Positives = 62/140 (44%), Gaps = 8/140 (5%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLA----R 207
EE+E+ +ER++R++ + + + Q + EPE +A D R
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR 1245
Query: 208 EHAQKCQ---QQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARR 264
E+ Q Q Q R+ + + G Q R +E+E+R +++R R EE + R +
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE-RDREQERRRWQQRDRHFPEEEQLEREEQ 1304
Query: 265 AQEALGDREPKPTRAGPREE 284
+ DR+ + + REE
Sbjct: 1305 KEAKRRDRKSQEEKQLLREE 1324
Score = 32.0 bits (71), Expect = 0.95
Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 6/122 (4%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
+E EE ++ R+ L+ E + QE + D + +E E L Q
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL------LQEGEEQ 1682
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGD 271
+ ++Q+R+ + + + + +EEQ+L R+ K E + R QE L
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR 1742
Query: 272 RE 273
+E
Sbjct: 1743 QE 1744
Score = 30.4 bits (67), Expect = 2.8
Identities = 28/121 (23%), Positives = 58/121 (47%), Gaps = 7/121 (5%)
Query: 155 EEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQ 214
E++ + +E +Q+L+ E + +++E + E +E + DR E + +
Sbjct: 1599 EDEQQLRRQEGQQQLRQERDRKFRE-----DEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 215 QQQREAEGSR-RPPRAEGSSQSWRQQEEEQRLFRERARA-KEEELRESRARRAQEALGDR 272
+Q+RE + R + Q ++ EE+Q +ER R +EEE + R R ++ L +
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 273 E 273
+
Sbjct: 1714 Q 1714
Score = 29.3 bits (64), Expect = 6.2
Identities = 31/151 (20%), Positives = 60/151 (39%), Gaps = 14/151 (9%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDR--LAREH 209
+EE+ E +W+++ + + + +E F E + S R L +
Sbjct: 735 QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR 794
Query: 210 AQKCQQQQREAEGSRRPPRAEGSSQSWRQQ---EEEQRLFRERARAKEEELRESRARRAQ 266
++ + ++R+ R P E Q RQ+ E+E + E +E+ R RA++ Q
Sbjct: 795 ERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEE----EEQLQRRERAQQLQ 850
Query: 267 EALGDREPKPTRAGPREEHPRGAGRGSLWRF 297
E + R +E+ R WR+
Sbjct: 851 EEEDGLQEDQERRRSQEQR-----RDQKWRW 876
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 52.8 bits (125), Expect = 5e-07
Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Query: 134 DGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQ 193
D TPG L + A+ + + +E E R K + E E + QE + R + + Q
Sbjct: 709 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEE-ERKRQEELRRQQEEILRRQQ 767
Query: 194 EPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERA-RA 252
E E + LAR ++ ++QRE E + R RQ+EEE+R +E A R
Sbjct: 768 EEERKRREEEELARRKQEEALRRQREQEIALR-----------RQREEEERQQQEEALRR 816
Query: 253 KEEELRESRARRAQEALGDREPKPTRAGPREE 284
EE RE RR QE L ++ + REE
Sbjct: 817 LEERRREEEERRKQEELLRKQEEEAAKWAREE 848
Score = 39.3 bits (90), Expect = 0.006
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 16/143 (11%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPE-SFSAWSDRLAREHA 210
E E + +K E +K Q EL + +E++ R + + +E E + + L R+
Sbjct: 734 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 793
Query: 211 QKC--------QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERAR--AKEEE---- 256
Q+ +++Q++ E RR + R+QEE R E A A+EEE
Sbjct: 794 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQR 853
Query: 257 -LRESRARRAQEALGDREPKPTR 278
L E+R R +EA R + R
Sbjct: 854 RLEENRLRMEEEAARLRHEEEER 876
Score = 35.0 bits (79), Expect = 0.11
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
Query: 152 EEEEEDDASKEREWRQKLQGEL--EDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREH 209
++EEE +E E ++ Q E QE+ R + + Q+ E+ +R RE
Sbjct: 766 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER-RREE 824
Query: 210 AQKCQQQQ---REAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQ 266
++ +Q++ ++ E + + R E +Q R +E R+ E AR + EE E R R+
Sbjct: 825 EERRKQEELLRKQEEEAAKWAREEEEAQR-RLEENRLRMEEEAARLRHEE--EERKRKEL 881
Query: 267 EALGDRE 273
E +E
Sbjct: 882 EVQRQKE 888
Score = 32.3 bits (72), Expect = 0.73
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 10/108 (9%)
Query: 187 DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSW---------- 236
D +T P +L + A K +Q++REAE + E Q
Sbjct: 705 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 764
Query: 237 RQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREE 284
RQQEEE++ E A+ ++ R +R QE R+ + +EE
Sbjct: 765 RQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
Score = 31.6 bits (70), Expect = 1.2
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 151 AEEEEEDDASKEREWRQKLQGELEDE----WQEVMGRFEGDASHETQEPESFSAWSDRLA 206
A ++E+ ++RE L+ + E+E +E + R E E + + R
Sbjct: 780 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL--RKQ 837
Query: 207 REHAQKCQQQQREAEGSRRPPRAEGSSQSWR-QQEEEQRLFRERARAKEEELRESRARRA 265
E A K +++ EA+ R ++ R + EEE+R +E +++EL R ++
Sbjct: 838 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR-QQQ 896
Query: 266 QEAL 269
QEAL
Sbjct: 897 QEAL 900
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 52.8 bits (125), Expect = 5e-07
Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Query: 134 DGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQ 193
D TPG L + A+ + + +E E R K + E E + QE + R + + Q
Sbjct: 736 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEE-ERKRQEELRRQQEEILRRQQ 794
Query: 194 EPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERA-RA 252
E E + LAR ++ ++QRE E + R RQ+EEE+R +E A R
Sbjct: 795 EEERKRREEEELARRKQEEALRRQREQEIALR-----------RQREEEERQQQEEALRR 843
Query: 253 KEEELRESRARRAQEALGDREPKPTRAGPREE 284
EE RE RR QE L ++ + REE
Sbjct: 844 LEERRREEEERRKQEELLRKQEEEAAKWAREE 875
Score = 39.3 bits (90), Expect = 0.006
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 16/143 (11%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPE-SFSAWSDRLAREHA 210
E E + +K E +K Q EL + +E++ R + + +E E + + L R+
Sbjct: 761 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 820
Query: 211 QKC--------QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERAR--AKEEE---- 256
Q+ +++Q++ E RR + R+QEE R E A A+EEE
Sbjct: 821 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQR 880
Query: 257 -LRESRARRAQEALGDREPKPTR 278
L E+R R +EA R + R
Sbjct: 881 RLEENRLRMEEEAARLRHEEEER 903
Score = 35.0 bits (79), Expect = 0.11
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
Query: 152 EEEEEDDASKEREWRQKLQGEL--EDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREH 209
++EEE +E E ++ Q E QE+ R + + Q+ E+ +R RE
Sbjct: 793 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER-RREE 851
Query: 210 AQKCQQQQ---REAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQ 266
++ +Q++ ++ E + + R E +Q R +E R+ E AR + EE E R R+
Sbjct: 852 EERRKQEELLRKQEEEAAKWAREEEEAQR-RLEENRLRMEEEAARLRHEE--EERKRKEL 908
Query: 267 EALGDRE 273
E +E
Sbjct: 909 EVQRQKE 915
Score = 32.3 bits (72), Expect = 0.73
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 10/108 (9%)
Query: 187 DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSW---------- 236
D +T P +L + A K +Q++REAE + E Q
Sbjct: 732 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 791
Query: 237 RQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREE 284
RQQEEE++ E A+ ++ R +R QE R+ + +EE
Sbjct: 792 RQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
Score = 31.6 bits (70), Expect = 1.2
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 151 AEEEEEDDASKEREWRQKLQGELEDE----WQEVMGRFEGDASHETQEPESFSAWSDRLA 206
A ++E+ ++RE L+ + E+E +E + R E E + + R
Sbjct: 807 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL--RKQ 864
Query: 207 REHAQKCQQQQREAEGSRRPPRAEGSSQSWR-QQEEEQRLFRERARAKEEELRESRARRA 265
E A K +++ EA+ R ++ R + EEE+R +E +++EL R ++
Sbjct: 865 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR-QQQ 923
Query: 266 QEAL 269
QEAL
Sbjct: 924 QEAL 927
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 52.8 bits (125), Expect = 5e-07
Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Query: 134 DGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQ 193
D TPG L + A+ + + +E E R K + E E + QE + R + + Q
Sbjct: 715 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEE-ERKRQEELRRQQEEILRRQQ 773
Query: 194 EPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERA-RA 252
E E + LAR ++ ++QRE E + R RQ+EEE+R +E A R
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQEIALR-----------RQREEEERQQQEEALRR 822
Query: 253 KEEELRESRARRAQEALGDREPKPTRAGPREE 284
EE RE RR QE L ++ + REE
Sbjct: 823 LEERRREEEERRKQEELLRKQEEEAAKWAREE 854
Score = 39.3 bits (90), Expect = 0.006
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 16/143 (11%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPE-SFSAWSDRLAREHA 210
E E + +K E +K Q EL + +E++ R + + +E E + + L R+
Sbjct: 740 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 799
Query: 211 QKC--------QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERAR--AKEEE---- 256
Q+ +++Q++ E RR + R+QEE R E A A+EEE
Sbjct: 800 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQR 859
Query: 257 -LRESRARRAQEALGDREPKPTR 278
L E+R R +EA R + R
Sbjct: 860 RLEENRLRMEEEAARLRHEEEER 882
Score = 35.0 bits (79), Expect = 0.11
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
Query: 152 EEEEEDDASKEREWRQKLQGEL--EDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREH 209
++EEE +E E ++ Q E QE+ R + + Q+ E+ +R RE
Sbjct: 772 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER-RREE 830
Query: 210 AQKCQQQQ---REAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQ 266
++ +Q++ ++ E + + R E +Q R +E R+ E AR + EE E R R+
Sbjct: 831 EERRKQEELLRKQEEEAAKWAREEEEAQR-RLEENRLRMEEEAARLRHEE--EERKRKEL 887
Query: 267 EALGDRE 273
E +E
Sbjct: 888 EVQRQKE 894
Score = 32.3 bits (72), Expect = 0.73
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 10/108 (9%)
Query: 187 DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSW---------- 236
D +T P +L + A K +Q++REAE + E Q
Sbjct: 711 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 770
Query: 237 RQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREE 284
RQQEEE++ E A+ ++ R +R QE R+ + +EE
Sbjct: 771 RQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Score = 31.6 bits (70), Expect = 1.2
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 151 AEEEEEDDASKEREWRQKLQGELEDE----WQEVMGRFEGDASHETQEPESFSAWSDRLA 206
A ++E+ ++RE L+ + E+E +E + R E E + + R
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL--RKQ 843
Query: 207 REHAQKCQQQQREAEGSRRPPRAEGSSQSWR-QQEEEQRLFRERARAKEEELRESRARRA 265
E A K +++ EA+ R ++ R + EEE+R +E +++EL R ++
Sbjct: 844 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR-QQQ 902
Query: 266 QEAL 269
QEAL
Sbjct: 903 QEAL 906
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 52.8 bits (125), Expect = 5e-07
Identities = 47/152 (30%), Positives = 69/152 (45%), Gaps = 13/152 (8%)
Query: 134 DGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQ 193
D TPG L + A+ + + +E E R K + E E + QE + R + + Q
Sbjct: 715 DTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEE-ERKRQEELRRQQEEILRRQQ 773
Query: 194 EPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERA-RA 252
E E + LAR ++ ++QRE E + R RQ+EEE+R +E A R
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQEIALR-----------RQREEEERQQQEEALRR 822
Query: 253 KEEELRESRARRAQEALGDREPKPTRAGPREE 284
EE RE RR QE L ++ + REE
Sbjct: 823 LEERRREEEERRKQEELLRKQEEEAAKWAREE 854
Score = 39.3 bits (90), Expect = 0.006
Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 16/143 (11%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPE-SFSAWSDRLAREHA 210
E E + +K E +K Q EL + +E++ R + + +E E + + L R+
Sbjct: 740 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 799
Query: 211 QKC--------QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERAR--AKEEE---- 256
Q+ +++Q++ E RR + R+QEE R E A A+EEE
Sbjct: 800 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQR 859
Query: 257 -LRESRARRAQEALGDREPKPTR 278
L E+R R +EA R + R
Sbjct: 860 RLEENRLRMEEEAARLRHEEEER 882
Score = 35.0 bits (79), Expect = 0.11
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
Query: 152 EEEEEDDASKEREWRQKLQGEL--EDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREH 209
++EEE +E E ++ Q E QE+ R + + Q+ E+ +R RE
Sbjct: 772 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEER-RREE 830
Query: 210 AQKCQQQQ---REAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQ 266
++ +Q++ ++ E + + R E +Q R +E R+ E AR + EE E R R+
Sbjct: 831 EERRKQEELLRKQEEEAAKWAREEEEAQR-RLEENRLRMEEEAARLRHEE--EERKRKEL 887
Query: 267 EALGDRE 273
E +E
Sbjct: 888 EVQRQKE 894
Score = 32.3 bits (72), Expect = 0.73
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 10/108 (9%)
Query: 187 DASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSW---------- 236
D +T P +L + A K +Q++REAE + E Q
Sbjct: 711 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR 770
Query: 237 RQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREE 284
RQQEEE++ E A+ ++ R +R QE R+ + +EE
Sbjct: 771 RQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Score = 31.6 bits (70), Expect = 1.2
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 8/124 (6%)
Query: 151 AEEEEEDDASKEREWRQKLQGELEDE----WQEVMGRFEGDASHETQEPESFSAWSDRLA 206
A ++E+ ++RE L+ + E+E +E + R E E + + R
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL--RKQ 843
Query: 207 REHAQKCQQQQREAEGSRRPPRAEGSSQSWR-QQEEEQRLFRERARAKEEELRESRARRA 265
E A K +++ EA+ R ++ R + EEE+R +E +++EL R ++
Sbjct: 844 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQR-QQQ 902
Query: 266 QEAL 269
QEAL
Sbjct: 903 QEAL 906
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 50.4 bits (119), Expect = 3e-06
Identities = 39/133 (29%), Positives = 64/133 (48%), Gaps = 13/133 (9%)
Query: 149 DSAEEEEEDDASKER-----EWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWS- 202
+ EEE+++ A ER E R++++ E + + + R E + QE E A
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Query: 203 DRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRA 262
+R+ E + +++QR E +R + + R +EEE+R ER R KEEE R +
Sbjct: 315 ERMREEEKRAAEERQRIKEEEKR-----AAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 369
Query: 263 RRAQEALGDREPK 275
R Q A + E K
Sbjct: 370 R--QRARAEEEEK 380
Score = 47.8 bits (112), Expect = 2e-05
Identities = 40/140 (28%), Positives = 61/140 (43%), Gaps = 7/140 (5%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRL---ARE 208
+EEE + S E +K++ E ++ + R E + + + +R A E
Sbjct: 240 QEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEE 299
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQ--EEEQRLFRERARAKEEELR--ESRARR 264
A ++++REAE R E + RQ+ EEE+R ER R KEEE R E R R
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359
Query: 265 AQEALGDREPKPTRAGPREE 284
+E E + EE
Sbjct: 360 KEEEKRAAEERQRARAEEEE 379
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/157 (24%), Positives = 69/157 (43%), Gaps = 26/157 (16%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHE-------------TQEP 195
D+ E ++ED +E E + +G + + EVM + S E ++EP
Sbjct: 179 DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEP 238
Query: 196 ---ESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARA 252
E SD ++ H +K +++ +E + R R E + + E+++++ ERAR
Sbjct: 239 KQEEEREQGSDEIS--HHEKMEEEDKERAEAER-ARLEAEERERIKAEQDKKIADERARI 295
Query: 253 KEEELRESRARRAQEALGDREPKPTRAGPREEHPRGA 289
+ EE ++ R +EA R REE R A
Sbjct: 296 EAEEKAAAQERERREA-------EERERMREEEKRAA 325
Score = 36.2 bits (82), Expect = 0.050
Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 16/126 (12%)
Query: 151 AEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHA 210
AE + +A K E ++ +GE E E E + + + +A+ E +E + R R
Sbjct: 524 AEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKK-----KREERRKV 578
Query: 211 QKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALG 270
+ ++Q+R+ E + R R +EEE+R +E + E E R + ++ L
Sbjct: 579 LEEEEQRRKQEEADRKLR----------EEEEKRRLKEEIERRRAEAAEKRQKMPEDGLS 628
Query: 271 DREPKP 276
D + KP
Sbjct: 629 D-DKKP 633
Score = 29.6 bits (65), Expect = 4.7
Identities = 26/136 (19%), Positives = 58/136 (42%), Gaps = 19/136 (13%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
+EEE A++ER+ ++ + +E Q E A E Q+ +E K
Sbjct: 346 KEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIK 405
Query: 213 CQQQQREAEG-------------SRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRE 259
++ +++ EG + +G + + Q + ++L ++ K+EE+++
Sbjct: 406 GEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKD 465
Query: 260 SRARRAQEALGDREPK 275
+ ++ D+EPK
Sbjct: 466 EKIKK------DKEPK 475
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 49.7 bits (117), Expect = 4e-06
Identities = 57/240 (23%), Positives = 93/240 (38%), Gaps = 29/240 (12%)
Query: 69 LHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAM 128
LH A A+ + L LL++ G + QD G T LHAAA G +L+ M
Sbjct: 221 LHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACS----ILAEALCDM 276
Query: 129 GIKNKDGETPGQILGWG--------PPWDSAEEEEEDDASK--EREWRQKLQGELEDEWQ 178
I+NK G+TP + G + E++ +K E + K+Q +
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKE 336
Query: 179 EVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQ 238
+++ E S E +E S+ S E + + + E E ++P S S
Sbjct: 337 KMLYEEETPKSQEMEEENKESSSSSSEEEEGEDEASESETEKEADKKPEAFVNHSNS--- 393
Query: 239 QEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFG 298
E + + + + S ARR L ++ + P++E P S WR G
Sbjct: 394 -ESKSSITEQIPAPAQNTFSASSARRFSSGLFNKPEE-----PKDESP------SSWRLG 441
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 22/157 (14%)
Query: 42 SAGRLVRAQALLQRHPGLD-VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDT 100
S+G + LL R ++ V+ LH+AC + + L+ A+ QD G T
Sbjct: 67 SSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWT 126
Query: 101 ALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPG--------------QILGWGP 146
LHAAA G ++F+ +++GI N +GE P Q+ G
Sbjct: 127 PLHAAASCGYLNIAEYFI----NHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGI 182
Query: 147 PWDSAEEEEEDDASKE-REWRQKLQGELEDEWQEVMG 182
+ + +EEE ++ R+W G++ED Q G
Sbjct: 183 DLEQSRKEEEQQMLQDARQWLN--SGKIEDVRQARSG 217
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform a [Homo sapiens]
Length = 982
Score = 49.7 bits (117), Expect = 4e-06
Identities = 57/240 (23%), Positives = 93/240 (38%), Gaps = 29/240 (12%)
Query: 69 LHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAM 128
LH A A+ + L LL++ G + QD G T LHAAA G +L+ M
Sbjct: 221 LHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACS----ILAEALCDM 276
Query: 129 GIKNKDGETPGQILGWG--------PPWDSAEEEEEDDASK--EREWRQKLQGELEDEWQ 178
I+NK G+TP + G + E++ +K E + K+Q +
Sbjct: 277 DIRNKLGQTPFDVADEGLVEHLELLQKKQNVLRSEKETRNKLIESDLNSKIQSGFFKNKE 336
Query: 179 EVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQ 238
+++ E S E +E S+ S E + + + E E ++P S S
Sbjct: 337 KMLYEEETPKSQEMEEENKESSSSSSEEEEGEDEASESETEKEADKKPEAFVNHSNS--- 393
Query: 239 QEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFG 298
E + + + + S ARR L ++ + P++E P S WR G
Sbjct: 394 -ESKSSITEQIPAPAQNTFSASSARRFSSGLFNKPEE-----PKDESP------SSWRLG 441
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 22/157 (14%)
Query: 42 SAGRLVRAQALLQRHPGLD-VDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDT 100
S+G + LL R ++ V+ LH+AC + + L+ A+ QD G T
Sbjct: 67 SSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWT 126
Query: 101 ALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPG--------------QILGWGP 146
LHAAA G ++F+ +++GI N +GE P Q+ G
Sbjct: 127 PLHAAASCGYLNIAEYFI----NHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGI 182
Query: 147 PWDSAEEEEEDDASKE-REWRQKLQGELEDEWQEVMG 182
+ + +EEE ++ R+W G++ED Q G
Sbjct: 183 DLEQSRKEEEQQMLQDARQWLN--SGKIEDVRQARSG 217
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 49.3 bits (116), Expect = 6e-06
Identities = 33/142 (23%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
++E E + KER R+K + E E E + G+ E + +E E ++ +E +
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRE--SRARRAQEAL 269
K +++++E + R + + +++ E+R RER + + E+ RE R +R ++ +
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171
Query: 270 GDREPKPTRAGPREEHPRGAGR 291
G++E + +E R R
Sbjct: 172 GEKEEERKEKERKERKKRERNR 193
Score = 45.4 bits (106), Expect = 8e-05
Identities = 38/146 (26%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
++EE + K R ++ +GE +++ ++ + G S E +E E +E +K
Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
Query: 213 CQQQQREAEGSRRPPRAE---GSSQSWRQQEE-EQRLFRERAR--AKEEELRESRARRAQ 266
+++++E E R R G + R+++E ++R RER R K+E R+ R R +
Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
Query: 267 EALGDREPKPTRAGPREEHPRGAGRG 292
E E K R R+ + R RG
Sbjct: 211 ERKKKEERKKERQKDRQTNWREKERG 236
Score = 37.0 bits (84), Expect = 0.030
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 9/139 (6%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
+E + + KE++ +K + + + EG+ + ++ E R ++E +
Sbjct: 75 KERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE--RGRTSKEGKE 132
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRE-------SRARR 264
+ ++++R+ E + R + + R+++E ++ R++ KEEE +E R R
Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
Query: 265 AQEALGDREPKPTRAGPRE 283
+E +RE K R +E
Sbjct: 193 RKERKKERERKERRERKKE 211
Score = 37.0 bits (84), Expect = 0.030
Identities = 31/141 (21%), Positives = 61/141 (43%), Gaps = 7/141 (4%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
+ E+E+ K+ R +G+ + +E + + +E E +R RE
Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE 167
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEA 268
Q ++++ E R+ + ++ R++E E++ RER K+E R+ + R +E
Sbjct: 168 RKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER---KKE--RKKKEERKKER 222
Query: 269 LGDREP--KPTRAGPREEHPR 287
DR+ + G RE R
Sbjct: 223 QKDRQTNWREKERGKRERKER 243
Score = 35.4 bits (80), Expect = 0.086
Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 13/119 (10%)
Query: 170 QGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRA 229
Q E+ + +E+ R EG E S+R ++ ++++RE E R+ R
Sbjct: 35 QSEIREREREIETRKEGKKERE----------SERKKERREREKRKREREKE--RKRERG 82
Query: 230 EGSSQSWRQQEEEQRLFRERARA-KEEELRESRARRAQEALGDREPKPTRAGPREEHPR 287
+ + R++EE +R R R + KE E +E R ++ ++ G + +EE R
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141
Score = 35.4 bits (80), Expect = 0.086
Identities = 25/101 (24%), Positives = 53/101 (52%), Gaps = 8/101 (7%)
Query: 152 EEEEEDDASKEREWRQKLQ-GELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHA 210
EE E++ KER+ R++ Q GE E+E +E + +E + +R +E
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK-----KERERKERR 206
Query: 211 QKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERAR 251
++ ++++++ E R+ R + +WR++E +R +ER +
Sbjct: 207 ERKKERKKKEE--RKKERQKDRQTNWREKERGKRERKERKK 245
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 48.9 bits (115), Expect = 8e-06
Identities = 40/108 (37%), Positives = 57/108 (52%), Gaps = 12/108 (11%)
Query: 192 TQEPESFS---AWSDRLAREHAQKCQQQQREAEGSRRPPRAE-----GSSQSWRQQEEEQ 243
T +PE + A RLARE +K ++++RE E R R E ++ R++EE +
Sbjct: 473 TTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESR 532
Query: 244 RLFRERARAKEEELR---ESRA-RRAQEALGDREPKPTRAGPREEHPR 287
RL E+AR KEE+L+ E RA R +EA + K A REE R
Sbjct: 533 RLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAER 580
Score = 40.8 bits (94), Expect = 0.002
Identities = 49/176 (27%), Positives = 79/176 (44%), Gaps = 27/176 (15%)
Query: 151 AEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHA 210
A E+ E + + RE Q ELE + +E + + + +E ES RL E A
Sbjct: 490 AREQREKEERERRE-----QEELERQKREELAQRVAEERTTRREEES-----RRLEAEQA 539
Query: 211 QKCQQQ-QREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARA---------KEEELRES 260
++ ++Q QR+AE R E + ++ RQ+EEE R+ E R +EE+ R
Sbjct: 540 REKEEQLQRQAE-ERALREREEAERAQRQKEEEARVREEAERVRQEREKHFQREEQERLE 598
Query: 261 RARRAQEAL-GDREPKPTRAGPREEHPRGAGRGSLWRFGDV-PWPC----PGGGDP 310
R +R +E + R + T ++ +G+L +V PC PG G P
Sbjct: 599 RKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTEVSALPCTTNAPGNGKP 654
Score = 31.2 bits (69), Expect = 1.6
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 14/102 (13%)
Query: 204 RLAREHAQKCQQQ--QREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELR--- 258
RLARE ++ ++Q RE R RA Q + + EE++ E R KEE R
Sbjct: 68 RLARERREEREKQLAAREIVWLEREERAR---QHYEKHLEERKKRLEEQRQKEERRRAAV 124
Query: 259 -ESRARRAQEALGDREPKPTRA-----GPREEHPRGAGRGSL 294
E R +R +E E R P+++H R + GSL
Sbjct: 125 EEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNRWSWGGSL 166
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 48.5 bits (114), Expect = 1e-05
Identities = 41/162 (25%), Positives = 66/162 (40%), Gaps = 17/162 (10%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRF---EGDASHETQEPESFSAWSDRLARE 208
+ E E D KERE ++K Q E++ E GR + + E + + +R RE
Sbjct: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389
Query: 209 H-------------AQKCQQQQREAEGSR-RPPRAEGSSQSWRQQEEEQRLFRERARAKE 254
+K + QRE E R R E R +E E++ RER R ++
Sbjct: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
Query: 255 EELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWR 296
+ + R R+ + P+ R+G + P RG W+
Sbjct: 450 TDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWK 491
Score = 43.1 bits (100), Expect = 4e-04
Identities = 39/153 (25%), Positives = 66/153 (43%), Gaps = 16/153 (10%)
Query: 129 GIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDA 188
G + +D +T GQ E E + DA KERE + + + + E R
Sbjct: 135 GERGRDRQTDGQ----------RERERQRDAEKERERQTDRERQRQTERNRQKEREREKN 184
Query: 189 SHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS-----RRPPRAEGSSQSWRQQEEEQ 243
E +E E ++ H+++ ++++RE E +R E Q ++E E+
Sbjct: 185 RQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREK 244
Query: 244 RLFRERARAKEEELRESRAR-RAQEALGDREPK 275
+ RERA +E E + R R R ++ DR K
Sbjct: 245 QAERERASERETERDKERERERDRDRDRDRRQK 277
Score = 42.7 bits (99), Expect = 5e-04
Identities = 33/132 (25%), Positives = 65/132 (49%), Gaps = 5/132 (3%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E E+ +ERE +++ + + ED E GR E + ET+ +DR +
Sbjct: 180 EREKNRQERRERERQREKENKTEDRHSE-RGR-ERERERETETETERKRQTDRERDRQRK 237
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGD 271
++++++AE R +E ++ +++E E+ R+R R ++E R++ +R + D
Sbjct: 238 TEREREKQAERER---ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Query: 272 REPKPTRAGPRE 283
RE + R RE
Sbjct: 295 RETERKRERQRE 306
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/152 (23%), Positives = 64/152 (42%), Gaps = 12/152 (7%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E++ E + + ERE + + E E + R + + +T DR +
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 212 KCQQQQREAEGSRRPPRA-EGSSQSWRQQEEEQRLFRERARAKEEEL-----------RE 259
+ ++++RE E +R+ R E + RQ+E E+ +ER R ++ + RE
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362
Query: 260 SRARRAQEALGDREPKPTRAGPREEHPRGAGR 291
R + +E +RE A REE R R
Sbjct: 363 GRRQAERERERERERDRQSAREREERERDRDR 394
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 12/135 (8%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
++ E+ + +ERE ++ + E E + Q R D +T+ A +R +
Sbjct: 198 ENKTEDRHSERGRERERERETETETERKRQTDRER---DRQRKTEREREKQAERERASER 254
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEA 268
++ ++++RE + R R RQ+E E++ R+R R E + RE+ +R ++
Sbjct: 255 ETERDKERERERDRDRDRDR--------RQKERERQTDRKRQRRTERD-RETERKRERQR 305
Query: 269 LGDREPKPTRAGPRE 283
+RE + R RE
Sbjct: 306 ERERERERNRKRERE 320
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/142 (28%), Positives = 65/142 (45%), Gaps = 15/142 (10%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E E E + +++RE ++ + E E + + E D E + DR + Q
Sbjct: 306 ERERERERNRKRERERERERERERQRET-----ERDREKERERKRKRQTEMDR--ERNRQ 358
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGD 271
++ +R+AE R R E QS R++EE +R R+R R KE E + + R G
Sbjct: 359 TGREGRRQAERERERER-ERDRQSAREREERER-DRDRDRQKERERQTEKDRD-----GQ 411
Query: 272 REPKPTRAGPRE-EHPRGAGRG 292
RE + R ++ E RG RG
Sbjct: 412 RETEKQREREKDRESERGRERG 433
Score = 36.6 bits (83), Expect = 0.039
Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
+ + E D +E+E ++ + E E E + GR +T D Q
Sbjct: 108 QTDRERDRQREKERNRQKERERETEREGERGR-----DRQTDGQRERERQRDAEKERERQ 162
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGD 271
+++QR+ E +R+ R + RQ+ E RER R KE + + + R +E +
Sbjct: 163 TDRERQRQTERNRQKEREREKN---RQERRE----RERQREKENKTEDRHSERGRERERE 215
Query: 272 RE 273
RE
Sbjct: 216 RE 217
Score = 35.0 bits (79), Expect = 0.11
Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 12/140 (8%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQ-----EPESFSAWSDRLA 206
E E D ++R+ ++ Q + E E + R E D E + E E +
Sbjct: 80 ERRREKDRHRKRDRHRERQRDREKERERQTDR-ERDRQREKERNRQKERERETEREGERG 138
Query: 207 REH---AQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR 263
R+ Q+ +++QR+AE R + + RQ E ++ RER + ++E R R
Sbjct: 139 RDRQTDGQRERERQRDAEKERE---RQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
Query: 264 RAQEALGDREPKPTRAGPRE 283
+ DR + R RE
Sbjct: 196 EKENKTEDRHSERGRERERE 215
Score = 33.9 bits (76), Expect = 0.25
Identities = 37/144 (25%), Positives = 60/144 (41%), Gaps = 10/144 (6%)
Query: 149 DSAEEEEEDDASKEREWR-QKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAR 207
D+ ++ E + KERE R +K Q E E + + R E D + ++
Sbjct: 48 DADGDDRERNRQKERERRREKRQTERETDRKRERRR-EKDRHRKRDRHRERQRDREKERE 106
Query: 208 EHAQKCQQQQREAEGSRRPPRA-----EGSSQSWRQQEEEQRLFRERARAKEEELRESRA 262
+ + +QRE E +R+ R EG RQ + ++ R+R KE E + R
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166
Query: 263 RRAQEALG---DREPKPTRAGPRE 283
R+ Q +RE + R RE
Sbjct: 167 RQRQTERNRQKEREREKNRQERRE 190
Score = 30.8 bits (68), Expect = 2.1
Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 211 QKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRA-QEAL 269
++ +Q++RE +R E + R++E+++ R+R R ++ + + R R+ +E
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 270 GDREPKPTRAGPREEHPRGAG 290
RE + R RE G
Sbjct: 115 RQREKERNRQKERERETEREG 135
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 47.8 bits (112), Expect = 2e-05
Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 4/142 (2%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
D EE +E R+ LQ E + + + + + ++ A +RLA E
Sbjct: 562 DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE 621
Query: 209 HAQK-CQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 267
A+K ++ E +RR E W QQEEE+R +E + K+EE +E R R+A E
Sbjct: 622 KAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE-RLRKAAE 680
Query: 268 A--LGDREPKPTRAGPREEHPR 287
A L ++ + R R E R
Sbjct: 681 AKRLAEQREQERREQERREQER 702
Score = 43.9 bits (102), Expect = 2e-04
Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 151 AEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHA 210
A ++E++A + R W Q Q E E QE++ + E QE +A + RLA +
Sbjct: 637 ARRKQEEEARRLR-WLQ--QEEEERRHQELLQK----KKEEEQERLRKAAEAKRLAEQRE 689
Query: 211 QKCQQQQREAEGSRRPPRAEGSSQSWRQQ--EEEQRLFRERARAKEEELRESRARRAQEA 268
Q+ ++Q+R + R R E + +Q E+E+R +ER +A+ E +A R Q+
Sbjct: 690 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 749
Query: 269 LGDREPKPTRAGPREEHPRGAGR 291
RE + + +EE R A R
Sbjct: 750 QLQRELEEKK--KKEEQQRLAER 770
Score = 34.7 bits (78), Expect = 0.15
Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 14/126 (11%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
++EEE + ++ ++L + E E +E R + E +E E R +E
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE-------RREQERQL 719
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEE-------ELRESRARR 264
Q+++RE E + + ++ R Q+E+ + E + KEE +L+E + ++
Sbjct: 720 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 779
Query: 265 AQEALG 270
A+EA G
Sbjct: 780 AKEAAG 785
Score = 34.7 bits (78), Expect = 0.15
Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 4/122 (3%)
Query: 152 EEEEE---DDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
EEE+E A +R Q+ Q E E +E R + E +E E A +R +
Sbjct: 669 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 728
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQ-SWRQQEEEQRLFRERARAKEEELRESRARRAQE 267
+ +++ +E E + R + + + ++++EEQ+ ER +E+E + A A +
Sbjct: 729 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 788
Query: 268 AL 269
AL
Sbjct: 789 AL 790
Score = 34.3 bits (77), Expect = 0.19
Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
+E+ + A +ER +K + + + E E +A + +E W + E +
Sbjct: 607 DEKTEKAKEERLAEEKAKKKAAAKKME-----EVEARRKQEEEARRLRWLQQEEEERRHQ 661
Query: 213 CQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 267
Q+++ E R +A + + Q+E+E+R R + + E+ R + RR QE
Sbjct: 662 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 716
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 47.8 bits (112), Expect = 2e-05
Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 4/142 (2%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
D EE +E R+ LQ E + + + + + ++ A +RLA E
Sbjct: 558 DKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE 617
Query: 209 HAQK-CQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 267
A+K ++ E +RR E W QQEEE+R +E + K+EE +E R R+A E
Sbjct: 618 KAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE-RLRKAAE 676
Query: 268 A--LGDREPKPTRAGPREEHPR 287
A L ++ + R R E R
Sbjct: 677 AKRLAEQREQERREQERREQER 698
Score = 43.9 bits (102), Expect = 2e-04
Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 151 AEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHA 210
A ++E++A + R W Q Q E E QE++ + E QE +A + RLA +
Sbjct: 633 ARRKQEEEARRLR-WLQ--QEEEERRHQELLQK----KKEEEQERLRKAAEAKRLAEQRE 685
Query: 211 QKCQQQQREAEGSRRPPRAEGSSQSWRQQ--EEEQRLFRERARAKEEELRESRARRAQEA 268
Q+ ++Q+R + R R E + +Q E+E+R +ER +A+ E +A R Q+
Sbjct: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 745
Query: 269 LGDREPKPTRAGPREEHPRGAGR 291
RE + + +EE R A R
Sbjct: 746 QLQRELEEKK--KKEEQQRLAER 766
Score = 34.7 bits (78), Expect = 0.15
Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 14/126 (11%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
++EEE + ++ ++L + E E +E R + E +E E R +E
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE-------RREQERQL 715
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEE-------ELRESRARR 264
Q+++RE E + + ++ R Q+E+ + E + KEE +L+E + ++
Sbjct: 716 AEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 775
Query: 265 AQEALG 270
A+EA G
Sbjct: 776 AKEAAG 781
Score = 34.7 bits (78), Expect = 0.15
Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 4/122 (3%)
Query: 152 EEEEE---DDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
EEE+E A +R Q+ Q E E +E R + E +E E A +R +
Sbjct: 665 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724
Query: 209 HAQKCQQQQREAEGSRRPPRAEGSSQ-SWRQQEEEQRLFRERARAKEEELRESRARRAQE 267
+ +++ +E E + R + + + ++++EEQ+ ER +E+E + A A +
Sbjct: 725 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASK 784
Query: 268 AL 269
AL
Sbjct: 785 AL 786
Score = 34.3 bits (77), Expect = 0.19
Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 5/115 (4%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
+E+ + A +ER +K + + + E E +A + +E W + E +
Sbjct: 603 DEKTEKAKEERLAEEKAKKKAAAKKME-----EVEARRKQEEEARRLRWLQQEEEERRHQ 657
Query: 213 CQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 267
Q+++ E R +A + + Q+E+E+R R + + E+ R + RR QE
Sbjct: 658 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQE 712
>gi|117320531 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform a [Homo sapiens]
Length = 900
Score = 47.4 bits (111), Expect = 2e-05
Identities = 23/45 (51%), Positives = 27/45 (60%)
Query: 68 PLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDA 112
PLH A + LLR+GADPA DRHGD+A+H A R G A
Sbjct: 530 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGA 574
>gi|117320540 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform b [Homo sapiens]
Length = 899
Score = 47.4 bits (111), Expect = 2e-05
Identities = 23/45 (51%), Positives = 27/45 (60%)
Query: 68 PLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDA 112
PLH A + LLR+GADPA DRHGD+A+H A R G A
Sbjct: 530 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGA 574
>gi|117320527 nuclear factor of kappa light polypeptide gene
enhancer in B-cells 2 isoform b [Homo sapiens]
Length = 899
Score = 47.4 bits (111), Expect = 2e-05
Identities = 23/45 (51%), Positives = 27/45 (60%)
Query: 68 PLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDA 112
PLH A + LLR+GADPA DRHGD+A+H A R G A
Sbjct: 530 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGA 574
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 47.0 bits (110), Expect = 3e-05
Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 6/136 (4%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E E D +ERE + +GE + E + + D ET+ +DR +
Sbjct: 53 ERNRERDRDREREKQTDREGERQRERER-----DRDRQRETERERDKERETDRHTETDRE 107
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGD 271
+ +Q++RE E R R E + R+++ ++ RER R E E R R+ ++ +
Sbjct: 108 RQKQKEREMERVRDRER-EKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRE 166
Query: 272 REPKPTRAGPREEHPR 287
RE + R R+ +
Sbjct: 167 RERERKRERERKRETK 182
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E E E D +E + + E + + + M R D E Q+ +DR +
Sbjct: 87 ETERERDKERETDRHTETDRERQKQKEREMERVR-DREREKQKEMGRERQTDR------E 139
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGD 271
++++R+AE R R + R++E E++ RER R +E R + R ++ D
Sbjct: 140 TDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETD 199
Query: 272 REPKPTRAGPRE 283
R+ R RE
Sbjct: 200 RKRDRQRESERE 211
Score = 34.3 bits (77), Expect = 0.19
Identities = 28/143 (19%), Positives = 59/143 (41%), Gaps = 8/143 (5%)
Query: 149 DSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLARE 208
++ + + E +RE + + + ED E + + + + E +DR
Sbjct: 15 ETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGER 74
Query: 209 HAQKCQQQQREAEGSRRPPR-------AEGSSQSWRQQEEEQRLFRERARAKEEEL-RES 260
++ + + R+ E R + E + +Q+E E R+R R K++E+ RE
Sbjct: 75 QRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRER 134
Query: 261 RARRAQEALGDREPKPTRAGPRE 283
+ R + +R+ + R RE
Sbjct: 135 QTDRETDRERERQAERERETGRE 157
Score = 32.7 bits (73), Expect = 0.56
Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Query: 193 QEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARA 252
+E ++ S+R + ++ +++ R+ E ++ R EG Q R+++ +++ ER R
Sbjct: 35 KESKTEDRHSERDRQRDRERNRERDRDREREKQTDR-EGERQRERERDRDRQRETERERD 93
Query: 253 KEEEL-RESRARRAQEALGDREPKPTRAGPREE 284
KE E R + R ++ +RE + R RE+
Sbjct: 94 KERETDRHTETDRERQKQKEREMERVRDREREK 126
Score = 30.0 bits (66), Expect = 3.6
Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 207 REHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEEL-----RESR 261
R+ A++ + + R +E R+ R E + + R +E E++ RE R +E E RE+
Sbjct: 31 RDRAKESKTEDRHSERDRQRDR-ERNRERDRDREREKQTDREGERQRERERDRDRQRETE 89
Query: 262 ARRAQEALGDREPKPTRAGPREE 284
R +E DR + R +++
Sbjct: 90 RERDKERETDRHTETDRERQKQK 112
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 46.2 bits (108), Expect = 5e-05
Identities = 31/143 (21%), Positives = 64/143 (44%), Gaps = 9/143 (6%)
Query: 148 WDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAR 207
WD E+ E++ +ERE + + + E+ E +E M E ++ E +++
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE---EKMREQEEKMWEQEEKMQE 606
Query: 208 EHAQKCQQQQREAEGSRRPPRAEGSSQSWRQ----QEEEQRLF--RERARAKEEELRESR 261
+ + +Q+++ E E W Q QE+E++++ E+ R +EE++RE
Sbjct: 607 QEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666
Query: 262 ARRAQEALGDREPKPTRAGPREE 284
+ + RE + G E+
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEK 689
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/162 (22%), Positives = 67/162 (41%), Gaps = 29/162 (17%)
Query: 152 EEEEEDDASKEREWRQ--KLQGELEDEWQEVMGRFEGDASHETQEPESF----------- 198
E+EE+ +E+ W Q K+Q + E W++ +E + + QE E
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQ 644
Query: 199 --SAWS-DRLAREHAQKCQQQQREAEGSRRPPRAE-----GSSQSWRQQEEEQRLFRERA 250
W + RE +K ++Q+ + +G R + G + R+QEE+ R E+
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704
Query: 251 RAKEEEL--------RESRARRAQEALGDREPKPTRAGPREE 284
+EE++ + R +E + D++ K P E
Sbjct: 705 WGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHE 746
Score = 42.7 bits (99), Expect = 5e-04
Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Query: 148 WDSAE---EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDR 204
W+ E ++EE +++ WRQ+ E ED+ E + + E +R
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Query: 205 LAREHAQKCQQQ----QREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRES 260
L RE ++ ++Q Q+E + E ++W Q+E+ + R R R K+ E
Sbjct: 516 L-REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574
Query: 261 RARRAQEALGDREPK 275
R +E + ++E K
Sbjct: 575 MMREQEEKMQEQEEK 589
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/140 (17%), Positives = 67/140 (47%), Gaps = 19/140 (13%)
Query: 148 WDSAE---EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDR 204
W+ E E+EE +E+ W Q+ + + E+ +E + +E E+ ++
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR-------EEEETMREQEEK 414
Query: 205 LAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE-------- 256
+ ++ +Q+++E + R P + E + + QE+E++++ + + +++E
Sbjct: 415 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKK 474
Query: 257 -LRESRARRAQEALGDREPK 275
R+ + R ++ + ++E K
Sbjct: 475 MWRQEKMREQEDQMWEQEEK 494
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/157 (21%), Positives = 74/157 (47%), Gaps = 15/157 (9%)
Query: 148 WDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAR 207
W+ E+ +E++ +ERE + + + E E +E M + E + E +E E W +
Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE-ENMWEQEEKE----WQQQRLP 436
Query: 208 EHAQKCQQQQREAEGSRR----PPRAEGSSQSWRQQEEEQRLFRERARAKEEEL--RESR 261
E +K +Q++ E + + + W Q+++ R +E+ R +E+++ +E +
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR--QEKMREQEDQMWEQEEK 494
Query: 262 ARRAQEALGDREPKPTRAGP--REEHPRGAGRGSLWR 296
R ++ + D+E + RE+ R + +W+
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQ 531
Score = 38.9 bits (89), Expect = 0.008
Identities = 37/152 (24%), Positives = 69/152 (45%), Gaps = 21/152 (13%)
Query: 144 WGPPWDSAEEEEEDDASKEREWRQK-----LQGELEDEWQEVMGRFEG---DASHETQEP 195
W + E+E++ +E+ WRQ+ +G++ ++ +E M R E + E +E
Sbjct: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ-EEKMRRQEKRLREQEKELREQ 295
Query: 196 ESFSAWSDRLAREHAQKCQQQQR-----------EAEGSRRPPRAEGSSQSWRQQEEEQR 244
E +L + Q +Q+++ E + R+ R + R+QE++ R
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 245 LFRERARAKEEELRESRAR-RAQEALGDREPK 275
ER ++E LRE R R QE + ++E K
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEK 387
Score = 38.9 bits (89), Expect = 0.008
Identities = 29/128 (22%), Positives = 61/128 (47%), Gaps = 5/128 (3%)
Query: 153 EEEEDDASKEREWR-QKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E+E++ +E+E R QK E E++ QE + ++ E +RL + Q
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 346
Query: 212 KCQQQQREAEGSRRP-PRAEGSSQSWRQQEEEQRLFRERARAKEEEL---RESRARRAQE 267
+Q+Q+ + R + E + + E+++++ + + +EEE RE + R +E
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406
Query: 268 ALGDREPK 275
+ ++E K
Sbjct: 407 TMREQEEK 414
Score = 38.5 bits (88), Expect = 0.010
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 5/110 (4%)
Query: 148 WDSAEEE-EEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLA 206
WD E E+D+ +E+E R + Q ++ WQ+ E + E QE +++
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKM---WQQEEKMREEKKTQE-QEKKTWDQEEKMRE 558
Query: 207 REHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEE 256
E ++ +++ RE E R + Q + +E+E++++ + + +E+E
Sbjct: 559 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608
Score = 38.1 bits (87), Expect = 0.013
Identities = 27/128 (21%), Positives = 57/128 (44%), Gaps = 6/128 (4%)
Query: 154 EEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKC 213
E+ED ++ E + + ++ D+ + + + E E + E W +K
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 214 QQQQR----EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRAR--RAQE 267
Q+Q++ + E R R + R++EE R E+ + +EE++RE + +E
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602
Query: 268 ALGDREPK 275
+ ++E K
Sbjct: 603 KMQEQEEK 610
Score = 36.6 bits (83), Expect = 0.039
Identities = 26/119 (21%), Positives = 52/119 (43%), Gaps = 5/119 (4%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
EE+ + K RE +K+ + E W++ E + QE + D RE +
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE--QDERLREKEE 373
Query: 212 KCQQQQR---EAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQE 267
+ ++Q++ + E + R + R++EE R E+ + +EE + E + Q+
Sbjct: 374 RMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 432
Score = 33.9 bits (76), Expect = 0.25
Identities = 28/131 (21%), Positives = 60/131 (45%), Gaps = 15/131 (11%)
Query: 152 EEEEEDDASKEREWRQ--KLQGELEDEWQEVMGRFEGDASHETQEP----ESFSAWS-DR 204
E+EE+ +E+ W Q K++ + E W++ +E + QE + W D
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 366
Query: 205 LAREHAQKCQQQQR---EAEGSRRPPRAEGSSQSWRQQEE-----EQRLFRERARAKEEE 256
RE ++ ++Q++ + E + R + R++EE E+++ ++ E+E
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426
Query: 257 LRESRARRAQE 267
+E + +R E
Sbjct: 427 EKEWQQQRLPE 437
Score = 33.5 bits (75), Expect = 0.33
Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 14/129 (10%)
Query: 148 WDSAEEEEEDDA---SKEREWRQ-KLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSD 203
W+ E+E + KE+ W Q K+Q + E W++ E E + W
Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE----EKIRDQEEMWGQEKKMWRQ 478
Query: 204 RLAREHAQKCQQQQ---REAEGSRRPPRAEGSSQSWRQQEEEQRLFRERAR--AKEEELR 258
RE + +Q+ R+ E Q R +E+E+R+ RE+ + +EE++R
Sbjct: 479 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM-REQKKMWQQEEKMR 537
Query: 259 ESRARRAQE 267
E + + QE
Sbjct: 538 EEKKTQEQE 546
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 45.4 bits (106), Expect = 8e-05
Identities = 37/140 (26%), Positives = 63/140 (45%), Gaps = 10/140 (7%)
Query: 155 EEDDASKEREWRQKLQGEL----EDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHA 210
E+++ +E+E R + Q E E+ +E R ++ E +RL +
Sbjct: 203 EQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEE 262
Query: 211 QKCQQQQREAEGSRRPPRAEG--SSQSWRQQEEEQRLFRERARAKEEELR----ESRARR 264
+ C+Q++R E R E Q R +E+E+RL + R +E+E R E R R
Sbjct: 263 RLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLRE 322
Query: 265 AQEALGDREPKPTRAGPREE 284
+E L ++E P + EE
Sbjct: 323 QEERLCEQEKLPGQERLLEE 342
Score = 38.1 bits (87), Expect = 0.013
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%)
Query: 155 EEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQ----EPESFSAWSDRLAREHA 210
E+++ +E+E R + Q E E +E + E + + + E +RL +
Sbjct: 224 EQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEE 283
Query: 211 QKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALG 270
+ C+Q++R E R E + R+QEE ER R +EE L E QE L
Sbjct: 284 RLCEQEERLREQEERLCEQE---ERLREQEERLCEQEERLREQEERLCEQEKLPGQERLL 340
Query: 271 DREPKPTRAGPREE 284
+ K R+E
Sbjct: 341 EEVEKLLEQERRQE 354
Score = 36.6 bits (83), Expect = 0.039
Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 11/127 (8%)
Query: 155 EEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKCQ 214
E+++ +E+E R Q E E +E R ++ E +RL + + +
Sbjct: 266 EQEERLREQEERLHEQEERLCEQEE---RLREQEERLCEQEERLREQEERLCEQEERLRE 322
Query: 215 QQQREAEGSRRP------PRAEGSSQSWRQQEEEQRLF-RERARAKEEELRE-SRARRAQ 266
Q++R E + P E + R+QEE++RL RER + EEL E R R+
Sbjct: 323 QEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQD 382
Query: 267 EALGDRE 273
E L +E
Sbjct: 383 ERLWQQE 389
Score = 32.7 bits (73), Expect = 0.56
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 21/144 (14%)
Query: 126 SAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREW-RQKLQGELED-EWQEVMGR 183
S +KN+ E GP ++E + KE E ++LQ E+E+ + ++ R
Sbjct: 136 SLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNR 195
Query: 184 FEGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQ 243
+ + E +E +RL + + C+Q++R R+QEE
Sbjct: 196 RQEERLREQEE--RLREQEERLREQEERLCEQEER-----------------LREQEERL 236
Query: 244 RLFRERARAKEEELRESRARRAQE 267
R ER +EE LRE R ++
Sbjct: 237 REQEERLCEQEERLREHEERLCEQ 260
Score = 30.8 bits (68), Expect = 2.1
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 10/84 (11%)
Query: 202 SDRLAREHAQKCQQQQREAEGS--------RRPPRAEGSSQSWRQQEEEQRLFRERARAK 253
++ L +E +Q Q E E + R+ R + R+QEE R ER +
Sbjct: 166 TNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQ 225
Query: 254 EEELR--ESRARRAQEALGDREPK 275
EE LR E R R +E L ++E +
Sbjct: 226 EERLREQEERLREQEERLCEQEER 249
>gi|32484977 angiomotin like 2 [Homo sapiens]
Length = 780
Score = 45.4 bits (106), Expect = 8e-05
Identities = 90/359 (25%), Positives = 132/359 (36%), Gaps = 44/359 (12%)
Query: 4 PSPQVPE----EEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGL 59
P PQ P E +T+V P+ + Q E R + ++ Q Q++ L
Sbjct: 209 PPPQYPHVVLAHETTTAVTDPRYRARGSPHFQHAEVRILQAQVPPVFLQQQ---QQYQYL 265
Query: 60 DVDAGQPPPLHRACARH------DAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAY 113
PPP H A H PA+ + A A + A R+
Sbjct: 266 QQSQEHPPPPHPAALGHGPLSSLSPPAVEGPVSAQASSATSGSAHLAQMEAVLRENARLQ 325
Query: 114 TD---FFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQ 170
D L S A I+ + E I +S + E+ R K+
Sbjct: 326 RDNERLQRELESSAEKAGRIEKLESE----IQRLSEAHESLTRASSKREALEKTMRNKMD 381
Query: 171 GE---LEDEWQEVMGRFEGD---ASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGSR 224
E L+D +++ R E + +TQE ++ S D +A+ AQ +QQQ + + R
Sbjct: 382 SEMRRLQDFNRDLRERLESANRRLASKTQEAQAGS--QDMVAKLLAQSYEQQQEQEKLER 439
Query: 225 RPPRAEGSSQSWRQQEE--EQRLFRERARAK--EEELRESRA-----RRAQEALGD---- 271
G+ + R++ E EQ L + RA EEELR+ +A R Q+ALG
Sbjct: 440 EMALLRGAIEDQRRRAELLEQALGNAQGRAARAEEELRKKQAYVEKVERLQQALGQLQAA 499
Query: 272 ---REPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQ 327
RE R R E A R + G GG PE A L + EEQ
Sbjct: 500 CEKREQLELRLRTRLEQELKALRAQQRQAGAPGGSSGSGGSPELSALRLSEQLREKEEQ 558
>gi|119220598 apolipoprotein B48 receptor [Homo sapiens]
Length = 1088
Score = 45.1 bits (105), Expect = 1e-04
Identities = 56/238 (23%), Positives = 85/238 (35%), Gaps = 17/238 (7%)
Query: 102 LHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDAS- 160
LH A R D+ F LL + + + E G ++ G EEE ++D
Sbjct: 11 LHQALRGALDSLGTFVSYLLGDAVPTVEREAQAAEELG-VVAVGKTGKIVEEEAQEDLEG 69
Query: 161 ---KEREWRQKLQGELEDEWQEVMGRFE------GDASHETQEPESFSAWSDRLAREHAQ 211
+ E +L+G +D EV GD S + E + + A+ A
Sbjct: 70 LRGSQNEGAGRLRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAK--AA 127
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGD 271
+CQ+ E ++ G+ Q Q +E++ E+ +EE LR +E +
Sbjct: 128 RCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNREERLRSWEQEEEEEEVRA 187
Query: 272 REPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGA 329
REP R E G G G P G + E A EE GA
Sbjct: 188 REPGMARGAESEWTWHGETEGKAGAVG----PKAAGDNREMEQGVREADAGETEEPGA 241
Score = 39.3 bits (90), Expect = 0.006
Identities = 46/167 (27%), Positives = 64/167 (38%), Gaps = 23/167 (13%)
Query: 135 GETPGQILGWGPPWDSAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQE 194
GE +LG G WDS E+EE L+G E+E V GR + E++E
Sbjct: 770 GEALEGVLGQG--WDSKEKEEAAAGEHAGGQEFGLEGSAEEE---VTGRGSQVEAFESRE 824
Query: 195 PESFSAWSDRLAREHAQKCQQ---------QQREAEGSRRPPRAEGSSQSWRQQEEEQRL 245
W R+ E + + Q AEG A G + W EEE
Sbjct: 825 G---GPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVG 881
Query: 246 FRERARAKEEELR------ESRARRAQEALGDREPKPTRAGPREEHP 286
++ER + ++ E R E A R +A G RA +E P
Sbjct: 882 WQEREQREDSEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEP 928
Score = 30.4 bits (67), Expect = 2.8
Identities = 43/173 (24%), Positives = 62/173 (35%), Gaps = 39/173 (22%)
Query: 134 DGETPGQILGWGPPWDSAEEE---EEDDASKER------EWRQKLQGELEDEWQEVMGRF 184
DGE G P EEE EE +A++ EW + + E+MG
Sbjct: 502 DGEAEGTADLEATPEARPEEELTGEESEAAQTSCGLLGVEWGGLTHSVTKGQGPELMG-- 559
Query: 185 EGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAE------GSRRPPRAEGSSQSWR- 237
A T++PE A L A ++Q+R E GS +P +E +W
Sbjct: 560 --GAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAFPGAWEN 617
Query: 238 -------------------QQEEEQRLFRERARAKEEELRESRARRAQEALGD 271
Q+EEE+ + A+ E RES EA G+
Sbjct: 618 RTRKDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGE 670
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 45.1 bits (105), Expect = 1e-04
Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 19/125 (15%)
Query: 150 SAEEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREH 209
S EE E + KERE ++L+ E E E ++ E + E Q+ + +
Sbjct: 500 SPEEIREREREKEREREKELEKEQEQEREK-----EREKDRERQQEKE----------KE 544
Query: 210 AQKCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEAL 269
+K Q++QRE E R+ E + RQ+E+E+ L + + + KE EL + R + +E +
Sbjct: 545 LEKEQEKQREMEKERKQ---EKEKELERQKEKEKELQKMKEQEKECELEKER-EKLEEKI 600
Query: 270 GDREP 274
REP
Sbjct: 601 EPREP 605
Score = 30.0 bits (66), Expect = 3.6
Identities = 32/170 (18%), Positives = 67/170 (39%), Gaps = 3/170 (1%)
Query: 159 ASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAR--EHAQKCQQQ 216
A ++ W+Q+ + + E R + E + +A +++L R E ++Q
Sbjct: 439 ADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQ 498
Query: 217 QREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKE-EELRESRARRAQEALGDREPK 275
E R E + ++E+EQ +ER + +E ++ +E + QE + E +
Sbjct: 499 PSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKE 558
Query: 276 PTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLE 325
+ +E + L + + C + E + + R P LE
Sbjct: 559 RKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLE 608
Score = 29.3 bits (64), Expect = 6.2
Identities = 23/135 (17%), Positives = 52/135 (38%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E+E+E + KERE ++ E + ++ + E + S +E F+ + + A
Sbjct: 582 EQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEAT 641
Query: 212 KCQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGD 271
+ GS+ P Q+ R R++ + K+++ ++ + +
Sbjct: 642 PVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVP 701
Query: 272 REPKPTRAGPREEHP 286
+P + P P
Sbjct: 702 SQPSSSTVPPPPHRP 716
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 167 QKLQGELEDEWQEVMGRFEGDASH-ETQEPESFS--AWSDRLARE----------HAQKC 213
+K +GE E+ E G E D SH E EP S L RE +++
Sbjct: 310 RKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEAL 369
Query: 214 QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDRE 273
+QQQ+ + +R P A ++Q + ER R +E++ RE R+ QE R
Sbjct: 370 KQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRR 429
Query: 274 PKPTRAGPREEHPRGAGR 291
+ +A REE R A R
Sbjct: 430 LEDMQALRREEERRQAER 447
Score = 30.8 bits (68), Expect = 2.1
Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 11/134 (8%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
EEE A +E+E+++K +LE++ Q E QE + + ++ QK
Sbjct: 439 EEERRQAEREQEYKRK---QLEEQRQS-----ERLQRQLQQEHAYLKSLQQQQQQQQLQK 490
Query: 213 CQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDR 272
QQQQ+ G R+P G + + R ER R +++ S +++
Sbjct: 491 -QQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQ--NSPLAKSKPGSTGP 547
Query: 273 EPKPTRAGPREEHP 286
EP +A P P
Sbjct: 548 EPPIPQASPGPPGP 561
Score = 30.0 bits (66), Expect = 3.6
Identities = 25/99 (25%), Positives = 58/99 (58%), Gaps = 7/99 (7%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E++EE +E++ R++ Q +L+++ Q+ R D +E E A ++ E+ +
Sbjct: 400 EQKEERRRVEEQQRREREQRKLQEKEQQ---RRLEDMQALRREEERRQAEREQ---EYKR 453
Query: 212 KCQQQQREAEGSRRPPRAEGS-SQSWRQQEEEQRLFRER 249
K ++QR++E +R + E + +S +QQ+++Q+L +++
Sbjct: 454 KQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQ 492
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 167 QKLQGELEDEWQEVMGRFEGDASH-ETQEPESFS--AWSDRLARE----------HAQKC 213
+K +GE E+ E G E D SH E EP S L RE +++
Sbjct: 310 RKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEAL 369
Query: 214 QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDRE 273
+QQQ+ + +R P A ++Q + ER R +E++ RE R+ QE R
Sbjct: 370 KQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRR 429
Query: 274 PKPTRAGPREEHPRGAGR 291
+ +A REE R A R
Sbjct: 430 LEDMQALRREEERRQAER 447
Score = 30.8 bits (68), Expect = 2.1
Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 11/134 (8%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
EEE A +E+E+++K +LE++ Q E QE + + ++ QK
Sbjct: 439 EEERRQAEREQEYKRK---QLEEQRQS-----ERLQRQLQQEHAYLKSLQQQQQQQQLQK 490
Query: 213 CQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDR 272
QQQQ+ G R+P G + + R ER R +++ S +++
Sbjct: 491 -QQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQ--NSPLAKSKPGSTGP 547
Query: 273 EPKPTRAGPREEHP 286
EP +A P P
Sbjct: 548 EPPIPQASPGPPGP 561
Score = 30.0 bits (66), Expect = 3.6
Identities = 25/99 (25%), Positives = 58/99 (58%), Gaps = 7/99 (7%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E++EE +E++ R++ Q +L+++ Q+ R D +E E A ++ E+ +
Sbjct: 400 EQKEERRRVEEQQRREREQRKLQEKEQQ---RRLEDMQALRREEERRQAEREQ---EYKR 453
Query: 212 KCQQQQREAEGSRRPPRAEGS-SQSWRQQEEEQRLFRER 249
K ++QR++E +R + E + +S +QQ+++Q+L +++
Sbjct: 454 KQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQ 492
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 167 QKLQGELEDEWQEVMGRFEGDASH-ETQEPESFS--AWSDRLARE----------HAQKC 213
+K +GE E+ E G E D SH E EP S L RE +++
Sbjct: 310 RKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEAL 369
Query: 214 QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDRE 273
+QQQ+ + +R P A ++Q + ER R +E++ RE R+ QE R
Sbjct: 370 KQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRR 429
Query: 274 PKPTRAGPREEHPRGAGR 291
+ +A REE R A R
Sbjct: 430 LEDMQALRREEERRQAER 447
Score = 30.8 bits (68), Expect = 2.1
Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 11/134 (8%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
EEE A +E+E+++K +LE++ Q E QE + + ++ QK
Sbjct: 439 EEERRQAEREQEYKRK---QLEEQRQS-----ERLQRQLQQEHAYLKSLQQQQQQQQLQK 490
Query: 213 CQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDR 272
QQQQ+ G R+P G + + R ER R +++ S +++
Sbjct: 491 -QQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQ--NSPLAKSKPGSTGP 547
Query: 273 EPKPTRAGPREEHP 286
EP +A P P
Sbjct: 548 EPPIPQASPGPPGP 561
Score = 30.0 bits (66), Expect = 3.6
Identities = 25/99 (25%), Positives = 58/99 (58%), Gaps = 7/99 (7%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E++EE +E++ R++ Q +L+++ Q+ R D +E E A ++ E+ +
Sbjct: 400 EQKEERRRVEEQQRREREQRKLQEKEQQ---RRLEDMQALRREEERRQAEREQ---EYKR 453
Query: 212 KCQQQQREAEGSRRPPRAEGS-SQSWRQQEEEQRLFRER 249
K ++QR++E +R + E + +S +QQ+++Q+L +++
Sbjct: 454 KQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQ 492
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 167 QKLQGELEDEWQEVMGRFEGDASH-ETQEPESFS--AWSDRLARE----------HAQKC 213
+K +GE E+ E G E D SH E EP S L RE +++
Sbjct: 310 RKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSNSEAL 369
Query: 214 QQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDRE 273
+QQQ+ + +R P A ++Q + ER R +E++ RE R+ QE R
Sbjct: 370 KQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRR 429
Query: 274 PKPTRAGPREEHPRGAGR 291
+ +A REE R A R
Sbjct: 430 LEDMQALRREEERRQAER 447
Score = 30.8 bits (68), Expect = 2.1
Identities = 33/134 (24%), Positives = 56/134 (41%), Gaps = 11/134 (8%)
Query: 153 EEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQK 212
EEE A +E+E+++K +LE++ Q E QE + + ++ QK
Sbjct: 439 EEERRQAEREQEYKRK---QLEEQRQS-----ERLQRQLQQEHAYLKSLQQQQQQQQLQK 490
Query: 213 CQQQQREAEGSRRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDR 272
QQQQ+ G R+P G + + R ER R +++ S +++
Sbjct: 491 -QQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQ--NSPLAKSKPGSTGP 547
Query: 273 EPKPTRAGPREEHP 286
EP +A P P
Sbjct: 548 EPPIPQASPGPPGP 561
Score = 30.0 bits (66), Expect = 3.6
Identities = 25/99 (25%), Positives = 58/99 (58%), Gaps = 7/99 (7%)
Query: 152 EEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQ 211
E++EE +E++ R++ Q +L+++ Q+ R D +E E A ++ E+ +
Sbjct: 400 EQKEERRRVEEQQRREREQRKLQEKEQQ---RRLEDMQALRREEERRQAEREQ---EYKR 453
Query: 212 KCQQQQREAEGSRRPPRAEGS-SQSWRQQEEEQRLFRER 249
K ++QR++E +R + E + +S +QQ+++Q+L +++
Sbjct: 454 KQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQ 492
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,630,973
Number of Sequences: 37866
Number of extensions: 1050375
Number of successful extensions: 13147
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 346
Number of HSP's successfully gapped in prelim test: 569
Number of HSP's that attempted gapping in prelim test: 7302
Number of HSP's gapped (non-prelim): 3819
length of query: 381
length of database: 18,247,518
effective HSP length: 104
effective length of query: 277
effective length of database: 14,309,454
effective search space: 3963718758
effective search space used: 3963718758
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.