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Search of human proteins with 22212918
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22212918 ciliary neurotrophic factor receptor preproprotein
[Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22212918 ciliary neurotrophic factor receptor preproprotein [... 780 0.0
gi|4502931 ciliary neurotrophic factor receptor preproprotein [H... 780 0.0
gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor ... 140 1e-33
gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor [... 140 1e-33
gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [H... 140 1e-33
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi... 107 2e-23
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap... 105 7e-23
gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens] 102 6e-22
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 75 9e-14
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 67 2e-11
gi|24497438 interleukin 12B precursor [Homo sapiens] 67 3e-11
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 65 1e-10
gi|4506107 prolactin receptor [Homo sapiens] 63 5e-10
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 55 1e-07
gi|27437045 colony stimulating factor 3 receptor isoform d precu... 51 2e-06
gi|24496783 colony stimulating factor 3 receptor isoform c precu... 51 2e-06
gi|27437042 colony stimulating factor 3 receptor isoform b precu... 51 2e-06
gi|4503081 colony stimulating factor 3 receptor isoform a precur... 51 2e-06
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens] 50 2e-06
gi|169214048 PREDICTED: hypothetical protein [Homo sapiens] 40 0.003
gi|89057602 PREDICTED: hypothetical protein [Homo sapiens] 40 0.003
gi|37551995 PREDICTED: hypothetical protein [Homo sapiens] 40 0.003
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 39 0.006
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 39 0.006
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 39 0.006
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H... 39 0.006
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [... 39 0.006
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 37 0.022
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 37 0.022
gi|40254464 leptin receptor isoform 1 [Homo sapiens] 37 0.022
>gi|22212918 ciliary neurotrophic factor receptor preproprotein
[Homo sapiens]
Length = 372
Score = 780 bits (2014), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVN 60
MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVN
Sbjct: 1 MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVN 60
Query: 61 GTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNT 120
GTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNT
Sbjct: 61 GTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNT 120
Query: 121 YPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVS 180
YPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVS
Sbjct: 121 YPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVS 180
Query: 181 ISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPL 240
ISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPL
Sbjct: 181 ISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPL 240
Query: 241 KFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHAT 300
KFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHAT
Sbjct: 241 KFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHAT 300
Query: 301 PWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLAL 360
PWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLAL
Sbjct: 301 PWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLAL 360
Query: 361 AAAAATASSLLI 372
AAAAATASSLLI
Sbjct: 361 AAAAATASSLLI 372
>gi|4502931 ciliary neurotrophic factor receptor preproprotein [Homo
sapiens]
Length = 372
Score = 780 bits (2014), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVN 60
MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVN
Sbjct: 1 MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVN 60
Query: 61 GTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNT 120
GTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNT
Sbjct: 61 GTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNT 120
Query: 121 YPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVS 180
YPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVS
Sbjct: 121 YPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVS 180
Query: 181 ISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPL 240
ISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPL
Sbjct: 181 ISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPL 240
Query: 241 KFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHAT 300
KFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHAT
Sbjct: 241 KFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHAT 300
Query: 301 PWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLAL 360
PWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLAL
Sbjct: 301 PWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLAL 360
Query: 361 AAAAATASSLLI 372
AAAAATASSLLI
Sbjct: 361 AAAAATASSLLI 372
>gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor
[Homo sapiens]
Length = 422
Score = 140 bits (354), Expect = 1e-33
Identities = 105/312 (33%), Positives = 148/312 (47%), Gaps = 26/312 (8%)
Query: 12 VLAAAAAVVYAQRHSPQE--APHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDL---AP 66
++A A A+V A PQ P VQY + G V L C V+W +G P
Sbjct: 12 LVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGP 71
Query: 67 DLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFY 126
D G +LVL + G Y C D L V L +G PP PV+SC++ Y + F
Sbjct: 72 DSGLGHELVLAQADSTDEGTYICQTLDG-ALGGTVTLQLGYPPARPVVSCQAADY-ENFS 129
Query: 127 CSWH------LPTPTYIPNTFNVTVLHGSKIM--------VCEKDPALKNRCHIRYMHLF 172
C+W LPT Y+ + TVL C +DP RC + +
Sbjct: 130 CTWSPSQISGLPT-RYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFW 188
Query: 173 STIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTW 232
S +Y+++++ N LG + + +I++PDPP+ + VP PRRL +W P++W
Sbjct: 189 S--QYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASW 246
Query: 233 PDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKD-NEIGTWS 291
P F LKF L+YRP W VE + G ITDA AG + ++V+A+D + GTWS
Sbjct: 247 PCQPHFLLKFRLQYRPAQHPAWSTVEPA-GLEEVITDAVAGLPHAVRVSARDFLDAGTWS 305
Query: 292 DWSVAAHATPWT 303
WS A TP T
Sbjct: 306 TWSPEAWGTPST 317
>gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor
[Homo sapiens]
Length = 390
Score = 140 bits (354), Expect = 1e-33
Identities = 105/312 (33%), Positives = 148/312 (47%), Gaps = 26/312 (8%)
Query: 12 VLAAAAAVVYAQRHSPQE--APHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDL---AP 66
++A A A+V A PQ P VQY + G V L C V+W +G P
Sbjct: 12 LVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGP 71
Query: 67 DLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFY 126
D G +LVL + G Y C D L V L +G PP PV+SC++ Y + F
Sbjct: 72 DSGLGHELVLAQADSTDEGTYICQTLDG-ALGGTVTLQLGYPPARPVVSCQAADY-ENFS 129
Query: 127 CSWH------LPTPTYIPNTFNVTVLHGSKIM--------VCEKDPALKNRCHIRYMHLF 172
C+W LPT Y+ + TVL C +DP RC + +
Sbjct: 130 CTWSPSQISGLPT-RYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFW 188
Query: 173 STIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTW 232
S +Y+++++ N LG + + +I++PDPP+ + VP PRRL +W P++W
Sbjct: 189 S--QYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASW 246
Query: 233 PDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKD-NEIGTWS 291
P F LKF L+YRP W VE + G ITDA AG + ++V+A+D + GTWS
Sbjct: 247 PCQPHFLLKFRLQYRPAQHPAWSTVEPA-GLEEVITDAVAGLPHAVRVSARDFLDAGTWS 305
Query: 292 DWSVAAHATPWT 303
WS A TP T
Sbjct: 306 TWSPEAWGTPST 317
>gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 422
Score = 140 bits (354), Expect = 1e-33
Identities = 105/312 (33%), Positives = 148/312 (47%), Gaps = 26/312 (8%)
Query: 12 VLAAAAAVVYAQRHSPQE--APHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDL---AP 66
++A A A+V A PQ P VQY + G V L C V+W +G P
Sbjct: 12 LVAVATALVSASSPCPQAWGPPGVQYGQPGRSVKLCCPGVTAGDPVSWFRDGEPKLLQGP 71
Query: 67 DLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFY 126
D G +LVL + G Y C D L V L +G PP PV+SC++ Y + F
Sbjct: 72 DSGLGHELVLAQADSTDEGTYICQTLDG-ALGGTVTLQLGYPPARPVVSCQAADY-ENFS 129
Query: 127 CSWH------LPTPTYIPNTFNVTVLHGSKIM--------VCEKDPALKNRCHIRYMHLF 172
C+W LPT Y+ + TVL C +DP RC + +
Sbjct: 130 CTWSPSQISGLPT-RYLTSYRKKTVLGADSQRRSPSTGPWPCPQDPLGAARCVVHGAEFW 188
Query: 173 STIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTW 232
S +Y+++++ N LG + + +I++PDPP+ + VP PRRL +W P++W
Sbjct: 189 S--QYRINVTEVNPLGASTRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASW 246
Query: 233 PDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKD-NEIGTWS 291
P F LKF L+YRP W VE + G ITDA AG + ++V+A+D + GTWS
Sbjct: 247 PCQPHFLLKFRLQYRPAQHPAWSTVEPA-GLEEVITDAVAGLPHAVRVSARDFLDAGTWS 305
Query: 292 DWSVAAHATPWT 303
WS A TP T
Sbjct: 306 TWSPEAWGTPST 317
>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
sapiens]
Length = 468
Score = 107 bits (266), Expect = 2e-23
Identities = 111/383 (28%), Positives = 167/383 (43%), Gaps = 42/383 (10%)
Query: 11 AVLAAAAAVVYAQRHSPQEAPHVQYERL-GSDVTLPC-GTANWD-AAVTWRVN----GTD 63
A+LAA A + +R QE L G VTL C G D A V W + G+
Sbjct: 11 ALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSH 70
Query: 64 LAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPK 123
+ G +L+L ++L SG Y+C+ + V L V +PP EP LSC +
Sbjct: 71 PSRWAGMGRRLLLRSVQLHDSGNYSCYR--AGRPAGTVHLLVDVPPEEPQLSCFRKSPLS 128
Query: 124 GFYCSWHLPTPTYIPNTFNVTVLHGSKIM---------VCE-KDPALKNRCHIRYMHLFS 173
C W P P+ VL K C+ + K C + S
Sbjct: 129 NVVCEWG---PRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDS 185
Query: 174 TIKYKVSISVSNALGHNATAI-TFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTW 232
+ Y VS+ V++++G + TF I++PDPP N+ V NPR L VTWQ P +W
Sbjct: 186 SF-YIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSW 244
Query: 233 PDPESFPLKFFLRYRPLILDQWQHVELSDGTAH-TITDAYAGKEYIIQVAAKDN-EIGTW 290
+ + L+F LRYR + + D H I DA++G +++Q+ A++ G W
Sbjct: 245 -NSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEW 303
Query: 291 SDWSVAAHATPWTEE-----PRHLTTEAQAAETT----------TSTTSSLAPPPTTKIC 335
S+WS A TPWTE ++T QA T ++ +SL ++ +
Sbjct: 304 SEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSSSVP 363
Query: 336 DPGELGSGGGPSAPFLVSVPITL 358
P L +GG + L+ + I L
Sbjct: 364 LPTFLVAGGSLAFGTLLCIAIVL 386
>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
sapiens]
Length = 365
Score = 105 bits (262), Expect = 7e-23
Identities = 106/358 (29%), Positives = 153/358 (42%), Gaps = 32/358 (8%)
Query: 11 AVLAAAAAVVYAQRHSPQEAPHVQYERL-GSDVTLPC-GTANWD-AAVTWRVN----GTD 63
A+LAA A + +R QE L G VTL C G D A V W + G+
Sbjct: 11 ALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSH 70
Query: 64 LAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPK 123
+ G +L+L ++L SG Y+C+ + V L V +PP EP LSC +
Sbjct: 71 PSRWAGMGRRLLLRSVQLHDSGNYSCYR--AGRPAGTVHLLVDVPPEEPQLSCFRKSPLS 128
Query: 124 GFYCSWHLPTPTYIPNTFNVTVLHGSKIM---------VCE-KDPALKNRCHIRYMHLFS 173
C W P P+ VL K C+ + K C + S
Sbjct: 129 NVVCEWG---PRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDS 185
Query: 174 TIKYKVSISVSNALGHNATAI-TFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTW 232
+ Y VS+ V++++G + TF I++PDPP N+ V NPR L VTWQ P +W
Sbjct: 186 SF-YIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSW 244
Query: 233 PDPESFPLKFFLRYRPLILDQWQHVELSDGTAH-TITDAYAGKEYIIQVAAKDN-EIGTW 290
+ + L+F LRYR + + D H I DA++G +++Q+ A++ G W
Sbjct: 245 -NSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEW 303
Query: 291 SDWSVAAHATPWTEE-----PRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSG 343
S+WS A TPWTE ++T QA T + L PG G
Sbjct: 304 SEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPGSRRRG 361
>gi|14577917 Epstein-Barr virus induced 3 precursor [Homo sapiens]
Length = 229
Score = 102 bits (254), Expect = 6e-22
Identities = 60/196 (30%), Positives = 97/196 (49%), Gaps = 9/196 (4%)
Query: 112 PVLSCRSNTYPKGFYCSWHLP------TPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCH 165
P + CR++ YP CSW LP +P T+ + + C + C
Sbjct: 31 PRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCT 90
Query: 166 IRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVT 225
I + LFS Y ++++ + G +++ + F I+KPDPPE V P+ R+L+V
Sbjct: 91 ITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAE--RQLQVQ 148
Query: 226 WQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKD- 284
W+ P +WP PE F LK+++RY+ ++ V + T+ + Y +QVAA+D
Sbjct: 149 WEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDL 208
Query: 285 NEIGTWSDWSVAAHAT 300
+ G SDWS+ A AT
Sbjct: 209 TDYGELSDWSLPATAT 224
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 75.1 bits (183), Expect = 9e-14
Identities = 81/281 (28%), Positives = 118/281 (41%), Gaps = 43/281 (15%)
Query: 57 WRVNGTDLAPDL---LNGSQLVL-----HGLELGHSGLYACFHRDSWHLRHQVLLHVGLP 108
W +NG L P+L LN S L L +G C RD L L +VGLP
Sbjct: 76 WTLNGRRLPPELSRVLNASTLALALANLNGSRQRSGDNLVCHARDGSILAGSCL-YVGLP 134
Query: 109 PREPV-LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIM-----------VCEK 156
P +PV +SC S K C W P T LH + + CE+
Sbjct: 135 PEKPVNISCWSKNM-KDLTCRW-------TPGAHGETFLHTNYSLKYKLRWYGQDNTCEE 186
Query: 157 DPAL-KNRCHI-RYMHLFSTIKYKVSISVSNALGH-NATAITFDEFTIVKPDPPENVVAR 213
+ + CHI + + LF+ Y++ + +N LG + +T D +V DPP +V
Sbjct: 187 YHTVGPHSCHIPKDLALFTP--YEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVS 244
Query: 214 PVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHV-ELSDGTAHTITDAYA 272
V +L V W +P D F K+ +RYR W+ V ++S+ T+ +
Sbjct: 245 RVGGLEDQLSVRWVSPPALKD-FLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKP 303
Query: 273 GKEYIIQVAAK------DNEIGTWSDWS-VAAHATPWTEEP 306
G Y +QV + G WS+WS A +TP +E P
Sbjct: 304 GTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERP 344
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 67.4 bits (163), Expect = 2e-11
Identities = 56/209 (26%), Positives = 87/209 (41%), Gaps = 13/209 (6%)
Query: 106 GLPPREPV-LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGS-KIMVCEKDPALKNR 163
GLPP +P LSC N K C W T++ F + + K C+
Sbjct: 123 GLPPEKPKNLSCIVNEGKK-MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
Query: 164 CHIRYMHLFSTIKYKVSISVSNALGH-NATAITFDEFTIVKPDPPENVVARPVPSNPRRL 222
C + Y ++ + +V + NALG + I FD VKP+PP N+ L
Sbjct: 182 CTVDYSTVYF-VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
Query: 223 EVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDG----TAHTITDAYAGKEYII 278
++TW PS LK+ ++YR W + D ++ T+ D EY+
Sbjct: 241 KLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
Query: 279 QVAA-KDNEIGTWSDWSVAAHATPWTEEP 306
++ K++ G WSDWS A + + P
Sbjct: 298 RIRCMKEDGKGYWSDWSEEASGITYEDRP 326
>gi|24497438 interleukin 12B precursor [Homo sapiens]
Length = 328
Score = 67.0 bits (162), Expect = 3e-11
Identities = 74/300 (24%), Positives = 120/300 (40%), Gaps = 63/300 (21%)
Query: 39 GSDVTLPCGTANWDAAVTWRVNGTDLAPDLL-NGSQLVLHGLELGHSGLYACFHRDSWHL 97
G V L C T D +TW + D + ++L +G L + E G +G Y C H+ L
Sbjct: 43 GEMVVLTCDTPEEDG-ITWTL---DQSSEVLGSGKTLTIQVKEFGDAGQYTC-HKGGEVL 97
Query: 98 RHQVLL----HVGL-----------PPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFN 142
H +LL G+ P + L C + Y F C W T + TF+
Sbjct: 98 SHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL--TFS 155
Query: 143 VTVLHGSK--------------------------IMVCEKDPALKNRCHIRYMHLFSTIK 176
V GS + C++D A ++
Sbjct: 156 VKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAA--------EESLP 207
Query: 177 YKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPE 236
+V + + L + +F I+KPDPP+N+ +P+ N R++EV+W+ P TW P
Sbjct: 208 IEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWSTPH 266
Query: 237 S-FPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEI-GTWSDWS 294
S F L F ++ + + + +D T+ T+ K I V A+D +WS+W+
Sbjct: 267 SYFSLTFCVQVQGKSKREKKDRVFTDKTSATV---ICRKNASISVRAQDRYYSSSWSEWA 323
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 64.7 bits (156), Expect = 1e-10
Identities = 55/200 (27%), Positives = 84/200 (42%), Gaps = 13/200 (6%)
Query: 106 GLPPREPV-LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGS-KIMVCEKDPALKNR 163
GLPP +P LSC N K C W T++ F + + K C+
Sbjct: 123 GLPPEKPKNLSCIVNEGKK-MRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTS 181
Query: 164 CHIRYMHLFSTIKYKVSISVSNALGH-NATAITFDEFTIVKPDPPENVVARPVPSNPRRL 222
C + Y ++ + +V + NALG + I FD VKP+PP N+ L
Sbjct: 182 CTVDYSTVYF-VNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL 240
Query: 223 EVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSD----GTAHTITDAYAGKEYII 278
++TW PS LK+ ++YR W + D ++ T+ D EY+
Sbjct: 241 KLTWTNPSI---KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVF 297
Query: 279 QV-AAKDNEIGTWSDWSVAA 297
++ K++ G WSDWS A
Sbjct: 298 RIRCMKEDGKGYWSDWSEEA 317
>gi|4506107 prolactin receptor [Homo sapiens]
Length = 622
Score = 62.8 bits (151), Expect = 5e-10
Identities = 53/204 (25%), Positives = 93/204 (45%), Gaps = 12/204 (5%)
Query: 102 LLHVGLPPREP-VLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPAL 160
LL+ LPP +P + CRS + F C W T +P +++T + ++ E +
Sbjct: 21 LLNGQLPPGKPEIFKCRSPN-KETFTCWWRPGTDGGLPTNYSLTYHREGETLMHECPDYI 79
Query: 161 K---NRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFT-IVKPDPPENVVARPVP 216
N CH + Y + ++ +N +G + + + + T IV+PDPP +
Sbjct: 80 TGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQ 139
Query: 217 SNPRR--LEVTWQTPSTWPDPES--FPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYA 272
R+ L + W +P T D ++ F L + +R +P +W+ T I +
Sbjct: 140 PEDRKPYLWIKW-SPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIHFAGQQTEFKILSLHP 198
Query: 273 GKEYIIQVAAKDNEIGTWSDWSVA 296
G++Y++QV K + G WS WS A
Sbjct: 199 GQKYLVQVRCKPDH-GYWSAWSPA 221
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 54.7 bits (130), Expect = 1e-07
Identities = 51/198 (25%), Positives = 77/198 (38%), Gaps = 13/198 (6%)
Query: 107 LPPREPVLSCRSNTYPKGFYCSWHLPTPT-YIPNTFNVTVLHGSKIMVCEKDPAL-KNRC 164
LP + +SC Y K C+W T Y T T G K C + + +NR
Sbjct: 53 LPAKPENISC-VYYYRKNLTCTWSPGKETSYTQYTVKRTYAFGEKHDNCTTNSSTSENRA 111
Query: 165 HIRYMHLFSTI--KYKVSISVSNALGHNATAITFDEF-TIVKPDPPENVVARPVPSNPRR 221
+ TI Y + + N G + +T+ I K +PP+ +PV R
Sbjct: 112 SCSFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIAKTEPPKIFRVKPVLGIKRM 171
Query: 222 LEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELS-----DGTAHTITDAYAGKEY 276
+++ W P P S LK+ LR+R + W V + + +T EY
Sbjct: 172 IQIEWIKPEL--APVSSDLKYTLRFRTVNSTSWMEVNFAKNRKDKNQTYNLTGLQPFTEY 229
Query: 277 IIQVAAKDNEIGTWSDWS 294
+I + E WSDWS
Sbjct: 230 VIALRCAVKESKFWSDWS 247
>gi|27437045 colony stimulating factor 3 receptor isoform d
precursor [Homo sapiens]
Length = 783
Score = 50.8 bits (120), Expect = 2e-06
Identities = 77/326 (23%), Positives = 119/326 (36%), Gaps = 56/326 (17%)
Query: 13 LAAAAAVVYAQRHSPQEAPHVQYE----RLGSDVTLPC------GTANWDAAVTWRVNGT 62
L AA ++ S +E H+ LG +T C + + + WR+ G
Sbjct: 9 LTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRL-GA 67
Query: 63 DLAPD-----LLNGSQ---LVLHGLELGHSGLYACFH-RDSWHLRHQVLLHVGLPPREPV 113
+L P L +G+Q + L L + L C + +S + QV L G PP P
Sbjct: 68 ELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPH 127
Query: 114 -LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVL--------HGSKIMVC-EKDPALKNR 163
LSC N C W T++P +F + G I+ C KD ++
Sbjct: 128 NLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDG--QSH 185
Query: 164 CHIRYMHLFSTIKYKVSISVSNALGHN-ATAITFDEFTIVKPDPPENVVARP----VPSN 218
C I HL + + NALG + + + D +VK +PP P P
Sbjct: 186 CCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQ 245
Query: 219 PRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELS---------DGTAHTITD 269
L++ W+ W K LR++P Q E S + + +
Sbjct: 246 AGCLQLCWE---PWQPGLHINQKCELRHKP------QRGEASWALVGPLPLEALQYELCG 296
Query: 270 AYAGKEYIIQVAAKDNEI-GTWSDWS 294
Y +Q+ + G WSDWS
Sbjct: 297 LLPATAYTLQIRCIRWPLPGHWSDWS 322
>gi|24496783 colony stimulating factor 3 receptor isoform c
precursor [Homo sapiens]
Length = 863
Score = 50.8 bits (120), Expect = 2e-06
Identities = 77/326 (23%), Positives = 119/326 (36%), Gaps = 56/326 (17%)
Query: 13 LAAAAAVVYAQRHSPQEAPHVQYE----RLGSDVTLPC------GTANWDAAVTWRVNGT 62
L AA ++ S +E H+ LG +T C + + + WR+ G
Sbjct: 9 LTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRL-GA 67
Query: 63 DLAPD-----LLNGSQ---LVLHGLELGHSGLYACFH-RDSWHLRHQVLLHVGLPPREPV 113
+L P L +G+Q + L L + L C + +S + QV L G PP P
Sbjct: 68 ELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPH 127
Query: 114 -LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVL--------HGSKIMVC-EKDPALKNR 163
LSC N C W T++P +F + G I+ C KD ++
Sbjct: 128 NLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDG--QSH 185
Query: 164 CHIRYMHLFSTIKYKVSISVSNALGHN-ATAITFDEFTIVKPDPPENVVARP----VPSN 218
C I HL + + NALG + + + D +VK +PP P P
Sbjct: 186 CCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQ 245
Query: 219 PRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELS---------DGTAHTITD 269
L++ W+ W K LR++P Q E S + + +
Sbjct: 246 AGCLQLCWE---PWQPGLHINQKCELRHKP------QRGEASWALVGPLPLEALQYELCG 296
Query: 270 AYAGKEYIIQVAAKDNEI-GTWSDWS 294
Y +Q+ + G WSDWS
Sbjct: 297 LLPATAYTLQIRCIRWPLPGHWSDWS 322
>gi|27437042 colony stimulating factor 3 receptor isoform b
precursor [Homo sapiens]
Length = 769
Score = 50.8 bits (120), Expect = 2e-06
Identities = 77/326 (23%), Positives = 119/326 (36%), Gaps = 56/326 (17%)
Query: 13 LAAAAAVVYAQRHSPQEAPHVQYE----RLGSDVTLPC------GTANWDAAVTWRVNGT 62
L AA ++ S +E H+ LG +T C + + + WR+ G
Sbjct: 9 LTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRL-GA 67
Query: 63 DLAPD-----LLNGSQ---LVLHGLELGHSGLYACFH-RDSWHLRHQVLLHVGLPPREPV 113
+L P L +G+Q + L L + L C + +S + QV L G PP P
Sbjct: 68 ELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPH 127
Query: 114 -LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVL--------HGSKIMVC-EKDPALKNR 163
LSC N C W T++P +F + G I+ C KD ++
Sbjct: 128 NLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDG--QSH 185
Query: 164 CHIRYMHLFSTIKYKVSISVSNALGHN-ATAITFDEFTIVKPDPPENVVARP----VPSN 218
C I HL + + NALG + + + D +VK +PP P P
Sbjct: 186 CCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQ 245
Query: 219 PRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELS---------DGTAHTITD 269
L++ W+ W K LR++P Q E S + + +
Sbjct: 246 AGCLQLCWE---PWQPGLHINQKCELRHKP------QRGEASWALVGPLPLEALQYELCG 296
Query: 270 AYAGKEYIIQVAAKDNEI-GTWSDWS 294
Y +Q+ + G WSDWS
Sbjct: 297 LLPATAYTLQIRCIRWPLPGHWSDWS 322
>gi|4503081 colony stimulating factor 3 receptor isoform a precursor
[Homo sapiens]
Length = 836
Score = 50.8 bits (120), Expect = 2e-06
Identities = 77/326 (23%), Positives = 119/326 (36%), Gaps = 56/326 (17%)
Query: 13 LAAAAAVVYAQRHSPQEAPHVQYE----RLGSDVTLPC------GTANWDAAVTWRVNGT 62
L AA ++ S +E H+ LG +T C + + + WR+ G
Sbjct: 9 LTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRL-GA 67
Query: 63 DLAPD-----LLNGSQ---LVLHGLELGHSGLYACFH-RDSWHLRHQVLLHVGLPPREPV 113
+L P L +G+Q + L L + L C + +S + QV L G PP P
Sbjct: 68 ELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPH 127
Query: 114 -LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVL--------HGSKIMVC-EKDPALKNR 163
LSC N C W T++P +F + G I+ C KD ++
Sbjct: 128 NLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDG--QSH 185
Query: 164 CHIRYMHLFSTIKYKVSISVSNALGHN-ATAITFDEFTIVKPDPPENVVARP----VPSN 218
C I HL + + NALG + + + D +VK +PP P P
Sbjct: 186 CCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQ 245
Query: 219 PRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELS---------DGTAHTITD 269
L++ W+ W K LR++P Q E S + + +
Sbjct: 246 AGCLQLCWE---PWQPGLHINQKCELRHKP------QRGEASWALVGPLPLEALQYELCG 296
Query: 270 AYAGKEYIIQVAAKDNEI-GTWSDWS 294
Y +Q+ + G WSDWS
Sbjct: 297 LLPATAYTLQIRCIRWPLPGHWSDWS 322
>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
Length = 862
Score = 50.4 bits (119), Expect = 2e-06
Identities = 52/215 (24%), Positives = 89/215 (41%), Gaps = 22/215 (10%)
Query: 103 LHVGLPPREPV-LSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALK 161
+ VG+ P +P LSC C+W T++ + + L G K + +K
Sbjct: 118 IFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQ-LSGPKNLTWQKQC--- 173
Query: 162 NRCHIRYMHLFSTI-------KYKVSISVSNALGHNATA-ITFDEFTIVKPDPPENVVAR 213
+ Y+ + + ++ N+LG +++ TF IV+P PP ++ +
Sbjct: 174 KDIYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWDIRIK 233
Query: 214 PVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTA-HTITDAYA 272
++ R + W+ E L LRYRP W V ++ H + D
Sbjct: 234 FQKASVSRCTLYWRD-------EGLVLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKP 286
Query: 273 GKEYIIQVAAKDNEI-GTWSDWSVAAHATPWTEEP 306
EY Q+++K + G+WSDWS + A EEP
Sbjct: 287 FTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEP 321
>gi|169214048 PREDICTED: hypothetical protein [Homo sapiens]
Length = 881
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 26 SPQEAPHVQYERLGSDVTLPCGTANWDAA-VTWRVNGTDLAPDLLNGSQLVLHGLELGHS 84
S ++A ++ GS+VTL C A+ A +TW + A + GS+L+L + GH+
Sbjct: 408 SDRDAAPARFVTAGSNVTLRCAAASRPPADITWSLADPAEAA-VPAGSRLLLPAVGPGHA 466
Query: 85 GLYACFHRD-SWHLRHQVLLHV---GLPPREPVLSCRSNTYPKG--FYCSW 129
G YAC + R + LL++ LPP P S + F CSW
Sbjct: 467 GTYACLAANPRTGRRRRSLLNLTVADLPPGAPQCSVEGGPGDRSLRFRCSW 517
>gi|89057602 PREDICTED: hypothetical protein [Homo sapiens]
Length = 881
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 26 SPQEAPHVQYERLGSDVTLPCGTANWDAA-VTWRVNGTDLAPDLLNGSQLVLHGLELGHS 84
S ++A ++ GS+VTL C A+ A +TW + A + GS+L+L + GH+
Sbjct: 408 SDRDAAPARFVTAGSNVTLRCAAASRPPADITWSLADPAEAA-VPAGSRLLLPAVGPGHA 466
Query: 85 GLYACFHRD-SWHLRHQVLLHV---GLPPREPVLSCRSNTYPKG--FYCSW 129
G YAC + R + LL++ LPP P S + F CSW
Sbjct: 467 GTYACLAANPRTGRRRRSLLNLTVADLPPGAPQCSVEGGPGDRSLRFRCSW 517
>gi|37551995 PREDICTED: hypothetical protein [Homo sapiens]
Length = 867
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 26 SPQEAPHVQYERLGSDVTLPCGTANWDAA-VTWRVNGTDLAPDLLNGSQLVLHGLELGHS 84
S ++A ++ GS+VTL C A+ A +TW + A + GS+L+L + GH+
Sbjct: 408 SDRDAAPARFVTAGSNVTLRCAAASRPPADITWSLADPAEAA-VPAGSRLLLPAVGPGHA 466
Query: 85 GLYACFHRD-SWHLRHQVLLHV---GLPPREPVLSCRSNTYPKG--FYCSW 129
G YAC + R + LL++ LPP P S + F CSW
Sbjct: 467 GTYACLAANPRTGRRRRSLLNLTVADLPPGAPQCSVEGGPGDRSLRFRCSW 517
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 39.3 bits (90), Expect = 0.006
Identities = 86/398 (21%), Positives = 141/398 (35%), Gaps = 76/398 (19%)
Query: 29 EAPHVQYERLGSDVTLPCGTA---NWDAAVTWRVNGTDLAP------DLLNGSQLVLHGL 79
+ P E+ GS VT C + + ++TWR +G DL + +LV+H L
Sbjct: 517 QGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSL 576
Query: 80 ELGHSGLYACF---HRDSWHLRHQVLLHVGLPPREP--VLSCRSNTYPKGFYCSWHLPTP 134
+ G Y+C D R Q+L+ VG P P VLS SW P
Sbjct: 577 DYSDQGNYSCVASTELDVVESRAQLLV-VGSPGPVPRLVLSDLHLLTQSQVRVSWS-PAE 634
Query: 135 TYIPNTFNVTVLHGSKIMVCEKDPAL---KNRCHIRYMHLFSTIKYKVSISVSNALGHNA 191
+ + K M EK +L + L + Y ++ N G
Sbjct: 635 DHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGE 694
Query: 192 TAITFDEFTIVKPD--PPENVV-ARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRP 248
+ + T+V P+ P +N V + + + +TW+ P W D + +++ +++RP
Sbjct: 695 PSPVSE--TVVTPEAAPEKNPVDVKGEGNETTNMVITWK-PLRWMDWNAPQVQYRVQWRP 751
Query: 249 L-ILDQWQHVELSD--------------------------GTAHTITDAYAGKEYI---- 277
WQ +SD G +T Y+G++Y
Sbjct: 752 QGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIP 811
Query: 278 ----IQVAAKDNEIGTWSDWSVAA--------HATPWTE------EPRHLTTE--AQAAE 317
I++ + W +A + T W E RH+ + A
Sbjct: 812 ELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPAN 871
Query: 318 TTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVP 355
TT+ S L P + + G G GP++ F S P
Sbjct: 872 TTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTP 909
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 39.3 bits (90), Expect = 0.006
Identities = 86/398 (21%), Positives = 141/398 (35%), Gaps = 76/398 (19%)
Query: 29 EAPHVQYERLGSDVTLPCGTA---NWDAAVTWRVNGTDLAP------DLLNGSQLVLHGL 79
+ P E+ GS VT C + + ++TWR +G DL + +LV+H L
Sbjct: 522 QGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSL 581
Query: 80 ELGHSGLYACF---HRDSWHLRHQVLLHVGLPPREP--VLSCRSNTYPKGFYCSWHLPTP 134
+ G Y+C D R Q+L+ VG P P VLS SW P
Sbjct: 582 DYSDQGNYSCVASTELDVVESRAQLLV-VGSPGPVPRLVLSDLHLLTQSQVRVSWS-PAE 639
Query: 135 TYIPNTFNVTVLHGSKIMVCEKDPAL---KNRCHIRYMHLFSTIKYKVSISVSNALGHNA 191
+ + K M EK +L + L + Y ++ N G
Sbjct: 640 DHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGE 699
Query: 192 TAITFDEFTIVKPD--PPENVV-ARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRP 248
+ + T+V P+ P +N V + + + +TW+ P W D + +++ +++RP
Sbjct: 700 PSPVSE--TVVTPEAAPEKNPVDVKGEGNETTNMVITWK-PLRWMDWNAPQVQYRVQWRP 756
Query: 249 L-ILDQWQHVELSD--------------------------GTAHTITDAYAGKEYI---- 277
WQ +SD G +T Y+G++Y
Sbjct: 757 QGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIP 816
Query: 278 ----IQVAAKDNEIGTWSDWSVAA--------HATPWTE------EPRHLTTE--AQAAE 317
I++ + W +A + T W E RH+ + A
Sbjct: 817 ELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPAN 876
Query: 318 TTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVP 355
TT+ S L P + + G G GP++ F S P
Sbjct: 877 TTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTP 914
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 39.3 bits (90), Expect = 0.006
Identities = 86/398 (21%), Positives = 141/398 (35%), Gaps = 76/398 (19%)
Query: 29 EAPHVQYERLGSDVTLPCGTA---NWDAAVTWRVNGTDLAP------DLLNGSQLVLHGL 79
+ P E+ GS VT C + + ++TWR +G DL + +LV+H L
Sbjct: 522 QGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSL 581
Query: 80 ELGHSGLYACF---HRDSWHLRHQVLLHVGLPPREP--VLSCRSNTYPKGFYCSWHLPTP 134
+ G Y+C D R Q+L+ VG P P VLS SW P
Sbjct: 582 DYSDQGNYSCVASTELDVVESRAQLLV-VGSPGPVPRLVLSDLHLLTQSQVRVSWS-PAE 639
Query: 135 TYIPNTFNVTVLHGSKIMVCEKDPAL---KNRCHIRYMHLFSTIKYKVSISVSNALGHNA 191
+ + K M EK +L + L + Y ++ N G
Sbjct: 640 DHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGE 699
Query: 192 TAITFDEFTIVKPD--PPENVV-ARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRP 248
+ + T+V P+ P +N V + + + +TW+ P W D + +++ +++RP
Sbjct: 700 PSPVSE--TVVTPEAAPEKNPVDVKGEGNETTNMVITWK-PLRWMDWNAPQVQYRVQWRP 756
Query: 249 L-ILDQWQHVELSD--------------------------GTAHTITDAYAGKEYI---- 277
WQ +SD G +T Y+G++Y
Sbjct: 757 QGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIP 816
Query: 278 ----IQVAAKDNEIGTWSDWSVAA--------HATPWTE------EPRHLTTE--AQAAE 317
I++ + W +A + T W E RH+ + A
Sbjct: 817 ELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPAN 876
Query: 318 TTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVP 355
TT+ S L P + + G G GP++ F S P
Sbjct: 877 TTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTP 914
>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
sapiens]
Length = 435
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 5/69 (7%)
Query: 27 PQEAPHVQYERLGSDVTLPC-GTANWDAAVTWRVNGTDLAPDLLNGSQLVLHGLELGHSG 85
P+ P Y R G ++ L C +N A +W +NG L+G +L + + HSG
Sbjct: 334 PRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQ----LSGQKLFIPQITTNHSG 389
Query: 86 LYACFHRDS 94
LYAC R+S
Sbjct: 390 LYACSVRNS 398
>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
[Homo sapiens]
Length = 424
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 5/69 (7%)
Query: 27 PQEAPHVQYERLGSDVTLPC-GTANWDAAVTWRVNGTDLAPDLLNGSQLVLHGLELGHSG 85
P+ P Y R G ++ L C +N A +W +NG L+G +L + + HSG
Sbjct: 334 PRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQ----LSGQKLFIPQITTNHSG 389
Query: 86 LYACFHRDS 94
LYAC R+S
Sbjct: 390 LYACSVRNS 398
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 37.4 bits (85), Expect = 0.022
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Query: 201 IVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELS 260
+VKPDPP + L+++W +P P P + +K+ +I + ++
Sbjct: 234 MVKPDPPLGLHMEITDDG--NLKISWSSPPLVPFPLQYQVKYSENSTTVIREA---DKIV 288
Query: 261 DGTAHTITDAYAGKEYIIQVAAKD-NEIGTWSDWS 294
T+ + G Y +QV K + G WSDWS
Sbjct: 289 SATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 37.4 bits (85), Expect = 0.022
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Query: 201 IVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELS 260
+VKPDPP + L+++W +P P P + +K+ +I + ++
Sbjct: 234 MVKPDPPLGLHMEITDDG--NLKISWSSPPLVPFPLQYQVKYSENSTTVIREA---DKIV 288
Query: 261 DGTAHTITDAYAGKEYIIQVAAKD-NEIGTWSDWS 294
T+ + G Y +QV K + G WSDWS
Sbjct: 289 SATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
Length = 1165
Score = 37.4 bits (85), Expect = 0.022
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Query: 201 IVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELS 260
+VKPDPP + L+++W +P P P + +K+ +I + ++
Sbjct: 234 MVKPDPPLGLHMEITDDG--NLKISWSSPPLVPFPLQYQVKYSENSTTVIREA---DKIV 288
Query: 261 DGTAHTITDAYAGKEYIIQVAAKD-NEIGTWSDWS 294
T+ + G Y +QV K + G WSDWS
Sbjct: 289 SATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,252,066
Number of Sequences: 37866
Number of extensions: 903178
Number of successful extensions: 3770
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 120
Number of HSP's that attempted gapping in prelim test: 3439
Number of HSP's gapped (non-prelim): 412
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.