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Search of human proteins with 221316765
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
(380 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 765 0.0
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 724 0.0
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 721 0.0
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 720 0.0
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 719 0.0
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 645 0.0
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 582 e-166
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 579 e-165
gi|38201714 ELAV-like 1 [Homo sapiens] 481 e-136
gi|4506447 RNA binding motif, single stranded interacting protei... 116 4e-26
gi|8400718 RNA binding motif, single stranded interacting protei... 116 4e-26
gi|51317355 RNA binding motif, single stranded interacting prote... 113 2e-25
gi|51317353 RNA binding motif, single stranded interacting prote... 113 2e-25
gi|51317351 RNA binding motif, single stranded interacting prote... 113 2e-25
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 108 6e-24
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 108 6e-24
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 108 6e-24
gi|4506449 RNA binding motif, single stranded interacting protei... 107 2e-23
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 105 5e-23
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 104 2e-22
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 101 1e-21
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 100 2e-21
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 97 2e-20
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 96 4e-20
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 91 2e-18
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 91 2e-18
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 88 1e-17
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 87 3e-17
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 86 7e-17
gi|4505255 musashi 1 [Homo sapiens] 83 4e-16
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 765 bits (1975), Expect = 0.0
Identities = 380/380 (100%), Positives = 380/380 (100%)
Query: 1 MVMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE 60
MVMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE
Sbjct: 1 MVMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE 60
Query: 61 EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS 120
EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS
Sbjct: 61 EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS 120
Query: 121 YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF 180
YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF
Sbjct: 121 YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF 180
Query: 181 DKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQ 240
DKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQ
Sbjct: 181 DKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQ 240
Query: 241 AQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIF 300
AQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIF
Sbjct: 241 AQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIF 300
Query: 301 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 360
VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG
Sbjct: 301 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 360
Query: 361 YRLGDRVLQVSFKTNKAHKS 380
YRLGDRVLQVSFKTNKAHKS
Sbjct: 361 YRLGDRVLQVSFKTNKAHKS 380
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 724 bits (1870), Expect = 0.0
Identities = 366/380 (96%), Positives = 366/380 (96%), Gaps = 14/380 (3%)
Query: 1 MVMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE 60
MVMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE
Sbjct: 1 MVMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE 60
Query: 61 EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS 120
EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS
Sbjct: 61 EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS 120
Query: 121 YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF 180
YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF
Sbjct: 121 YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF 180
Query: 181 DKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQ 240
DKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQ
Sbjct: 181 DKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQ 240
Query: 241 AQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIF 300
AQRFRLDNLLNMAYGVK RFSPITIDGMTSLVGMNIPGHTGTGWCIF
Sbjct: 241 AQRFRLDNLLNMAYGVK--------------RFSPITIDGMTSLVGMNIPGHTGTGWCIF 286
Query: 301 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 360
VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG
Sbjct: 287 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 346
Query: 361 YRLGDRVLQVSFKTNKAHKS 380
YRLGDRVLQVSFKTNKAHKS
Sbjct: 347 YRLGDRVLQVSFKTNKAHKS 366
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 721 bits (1861), Expect = 0.0
Identities = 364/378 (96%), Positives = 364/378 (96%), Gaps = 14/378 (3%)
Query: 3 MIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF 62
MIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF
Sbjct: 20 MIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEF 79
Query: 63 RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 122
RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA
Sbjct: 80 RSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYA 139
Query: 123 RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 182
RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK
Sbjct: 140 RPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 199
Query: 183 RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ 242
RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ
Sbjct: 200 RIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQ 259
Query: 243 RFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 302
RFRLDNLLNMAYGVK RFSPITIDGMTSLVGMNIPGHTGTGWCIFVY
Sbjct: 260 RFRLDNLLNMAYGVK--------------RFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 305
Query: 303 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 362
NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR
Sbjct: 306 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 365
Query: 363 LGDRVLQVSFKTNKAHKS 380
LGDRVLQVSFKTNKAHKS
Sbjct: 366 LGDRVLQVSFKTNKAHKS 383
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 720 bits (1859), Expect = 0.0
Identities = 364/380 (95%), Positives = 364/380 (95%), Gaps = 14/380 (3%)
Query: 1 MVMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE 60
M IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE
Sbjct: 1 MEQIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQE 60
Query: 61 EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS 120
EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS
Sbjct: 61 EFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVS 120
Query: 121 YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF 180
YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF
Sbjct: 121 YARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRF 180
Query: 181 DKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQ 240
DKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQ
Sbjct: 181 DKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQ 240
Query: 241 AQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIF 300
AQRFRLDNLLNMAYGVK RFSPITIDGMTSLVGMNIPGHTGTGWCIF
Sbjct: 241 AQRFRLDNLLNMAYGVK--------------RFSPITIDGMTSLVGMNIPGHTGTGWCIF 286
Query: 301 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 360
VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG
Sbjct: 287 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 346
Query: 361 YRLGDRVLQVSFKTNKAHKS 380
YRLGDRVLQVSFKTNKAHKS
Sbjct: 347 YRLGDRVLQVSFKTNKAHKS 366
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 719 bits (1856), Expect = 0.0
Identities = 363/377 (96%), Positives = 363/377 (96%), Gaps = 14/377 (3%)
Query: 4 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR 63
IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR
Sbjct: 7 IISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFR 66
Query: 64 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR 123
SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR
Sbjct: 67 SLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR 126
Query: 124 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 183
PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR
Sbjct: 127 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 186
Query: 184 IEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQR 243
IEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQR
Sbjct: 187 IEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQR 246
Query: 244 FRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYN 303
FRLDNLLNMAYGVK RFSPITIDGMTSLVGMNIPGHTGTGWCIFVYN
Sbjct: 247 FRLDNLLNMAYGVK--------------RFSPITIDGMTSLVGMNIPGHTGTGWCIFVYN 292
Query: 304 LSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRL 363
LSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRL
Sbjct: 293 LSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRL 352
Query: 364 GDRVLQVSFKTNKAHKS 380
GDRVLQVSFKTNKAHKS
Sbjct: 353 GDRVLQVSFKTNKAHKS 369
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 645 bits (1664), Expect = 0.0
Identities = 324/374 (86%), Positives = 344/374 (91%), Gaps = 16/374 (4%)
Query: 8 MEPQVSNGPT-SNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLF 66
ME Q+SNGPT +NT+NGP++ N NC SP+ +G T+DSKTNLIVNYLPQNMTQEE +SLF
Sbjct: 1 METQLSNGPTCNNTANGPTTINNNCSSPVDSG-NTEDSKTNLIVNYLPQNMTQEELKSLF 59
Query: 67 GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 126
GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS
Sbjct: 60 GSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSS 119
Query: 127 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEA 186
ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTG+SRGVGFIRFDKRIEA
Sbjct: 120 ASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEA 179
Query: 187 EEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRL 246
EEAIKGLNGQKP GATEPITVKFANNPSQK++QA+LSQLYQSPNRRYPGPL QAQRFRL
Sbjct: 180 EEAIKGLNGQKPPGATEPITVKFANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRFRL 239
Query: 247 DNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSP 306
DNLLNMAYGVK RFSP+TIDGMTSL G+NIPGH GTGWCIFVYNL+P
Sbjct: 240 DNLLNMAYGVK--------------RFSPMTIDGMTSLAGINIPGHPGTGWCIFVYNLAP 285
Query: 307 DSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDR 366
D+DES+LWQ+FGPFGAV NVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDR
Sbjct: 286 DADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDR 345
Query: 367 VLQVSFKTNKAHKS 380
VLQVSFKTNK HK+
Sbjct: 346 VLQVSFKTNKTHKA 359
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 582 bits (1500), Expect = e-166
Identities = 300/382 (78%), Positives = 321/382 (84%), Gaps = 18/382 (4%)
Query: 1 MVMIISTMEPQVSNGPTSNT-SNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQ 59
+ I+ ME QV GP NGP + T TDDSKTNLIVNYLPQNMTQ
Sbjct: 2 VTQILGAMESQVGGGPAGPALPNGPL---------LGTNGATDDSKTNLIVNYLPQNMTQ 52
Query: 60 EEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKV 119
+EF+SLFGSIG+IESCKLVRDKITGQSLGYGFVNY DP DA+KAINTLNGL+LQTKTIKV
Sbjct: 53 DEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKV 112
Query: 120 SYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIR 179
SYARPSSASIRDANLYVSGLPKTM+QKE+EQLFSQYGRIITSRILVDQVTGVSRGVGFIR
Sbjct: 113 SYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIR 172
Query: 180 FDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHH 239
FDKRIEAEEAIKGLNGQKP GA EPITVKFANNPSQK+ QALL+ LYQS RRY GPLHH
Sbjct: 173 FDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHH 232
Query: 240 QAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIP-GHTGTGWC 298
Q QRFRLDNLLNMAYGVK P + RFSPI IDGM+ L G+ + G G GWC
Sbjct: 233 QTQRFRLDNLLNMAYGVK-------SPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWC 285
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
IFVYNLSP++DESVLWQLFGPFGAV NVKVIRDF TNKCKGFGFVTMTNYDEAAMAIASL
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 359 NGYRLGDRVLQVSFKTNKAHKS 380
NGYRLG+RVLQVSFKT+K HK+
Sbjct: 346 NGYRLGERVLQVSFKTSKQHKA 367
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 579 bits (1493), Expect = e-165
Identities = 299/382 (78%), Positives = 319/382 (83%), Gaps = 25/382 (6%)
Query: 1 MVMIISTMEPQVSNGPTSNT-SNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQ 59
+ I+ ME QV GP NGP + T TDDSKTNLIVNYLPQNMTQ
Sbjct: 2 VTQILGAMESQVGGGPAGPALPNGPL---------LGTNGATDDSKTNLIVNYLPQNMTQ 52
Query: 60 EEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKV 119
+EF+SLFGSIG+IESCKLVRDKITGQSLGYGFVNY DP DA+KAINTLNGL+LQTKTIKV
Sbjct: 53 DEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKV 112
Query: 120 SYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIR 179
SYARPSSASIRDANLYVSGLPKTM+QKE+EQLFSQYGRIITSRILVDQVTGVSRGVGFIR
Sbjct: 113 SYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIR 172
Query: 180 FDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHH 239
FDKRIEAEEAIKGLNGQKP GA EPITVKFANNPSQK+ QALL+ LYQS RRY GPLHH
Sbjct: 173 FDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHH 232
Query: 240 QAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIP-GHTGTGWC 298
Q QRFRLDNLLNMAYGVK RFSPI IDGM+ L G+ + G G GWC
Sbjct: 233 QTQRFRLDNLLNMAYGVK--------------RFSPIAIDGMSGLAGVGLSGGAAGAGWC 278
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
IFVYNLSP++DESVLWQLFGPFGAV NVKVIRDF TNKCKGFGFVTMTNYDEAAMAIASL
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 359 NGYRLGDRVLQVSFKTNKAHKS 380
NGYRLG+RVLQVSFKT+K HK+
Sbjct: 339 NGYRLGERVLQVSFKTSKQHKA 360
>gi|38201714 ELAV-like 1 [Homo sapiens]
Length = 326
Score = 481 bits (1239), Expect = e-136
Identities = 234/338 (69%), Positives = 273/338 (80%), Gaps = 27/338 (7%)
Query: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
D +TNLIVNYLPQNMTQ+E RSLF SIGE+ES KL+RDK+ G SLGYGFVNY+ KDAE
Sbjct: 16 DIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75
Query: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITS 161
+AINTLNGLRLQ+KTIKVSYARPSS I+DANLY+SGLP+TMTQK++E +FS++GRII S
Sbjct: 76 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 135
Query: 162 RILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQAL 221
R+LVDQ TG+SRGV FIRFDKR EAEEAI NG KP G++EPITVKFA NP+Q + AL
Sbjct: 136 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVAL 195
Query: 222 LSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGM 281
LSQLY SP RR+ GP+HHQAQRF RFSP+ +D M
Sbjct: 196 LSQLYHSPARRFGGPVHHQAQRF---------------------------RFSPMGVDHM 228
Query: 282 TSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 341
+ L G+N+PG+ +GWCIF+YNL D+DE +LWQ+FGPFGAV NVKVIRDFNTNKCKGFG
Sbjct: 229 SGLSGVNVPGNASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFG 288
Query: 342 FVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHK 379
FVTMTNY+EAAMAIASLNGYRLGD++LQVSFKTNK+HK
Sbjct: 289 FVTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNKSHK 326
>gi|4506447 RNA binding motif, single stranded interacting protein 1
isoform c [Homo sapiens]
Length = 403
Score = 116 bits (290), Expect = 4e-26
Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 32/241 (13%)
Query: 10 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 69
P P++ +SN SS++ N SKTNL + LP + T ++ L
Sbjct: 33 PMAPPSPSTTSSNNNSSSSSN-------SGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPY 85
Query: 70 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 129
G+I S K + DK T + GYGFV++ P A+KA++ L +Q + K P+
Sbjct: 86 GKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT---- 141
Query: 130 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 189
NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R + + E
Sbjct: 142 ---NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAV 197
Query: 190 IKGLNG---QKPSGA---TEPITVKFANNPSQKSSQALLSQLYQSPNRRYPG--PLHHQA 241
I NG + P G TEP+ KFA+ +K Q+PN+ P P H +
Sbjct: 198 IGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKR---------QNPNKYIPNGRPWHREG 248
Query: 242 Q 242
+
Sbjct: 249 E 249
Score = 45.4 bits (106), Expect = 8e-05
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 288 NIPGHTGTGWC------IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 341
N + +GW +++ L P + + L +L P+G + + K I D TNKCKG+G
Sbjct: 47 NSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYG 106
Query: 342 FVTMTNYDEAAMAIASL 358
FV + A A+++L
Sbjct: 107 FVDFDSPAAAQKAVSAL 123
Score = 37.0 bits (84), Expect = 0.029
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
Query: 359 NG 360
NG
Sbjct: 202 NG 203
>gi|8400718 RNA binding motif, single stranded interacting protein 1
isoform a [Homo sapiens]
Length = 406
Score = 116 bits (290), Expect = 4e-26
Identities = 79/241 (32%), Positives = 120/241 (49%), Gaps = 32/241 (13%)
Query: 10 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 69
P P++ +SN SS++ N SKTNL + LP + T ++ L
Sbjct: 33 PMAPPSPSTTSSNNNSSSSSN-------SGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPY 85
Query: 70 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 129
G+I S K + DK T + GYGFV++ P A+KA++ L +Q + K P+
Sbjct: 86 GKIVSTKAILDKTTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPT---- 141
Query: 130 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 189
NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R + + E
Sbjct: 142 ---NLYISNLPLSMDEQELENMLKPFGQVISTRILRDS-SGTSRGVGFARMESTEKCEAV 197
Query: 190 IKGLNG---QKPSGA---TEPITVKFANNPSQKSSQALLSQLYQSPNRRYPG--PLHHQA 241
I NG + P G TEP+ KFA+ +K Q+PN+ P P H +
Sbjct: 198 IGHFNGKFIKTPPGVSAPTEPLLCKFADGGQKKR---------QNPNKYIPNGRPWHREG 248
Query: 242 Q 242
+
Sbjct: 249 E 249
Score = 45.4 bits (106), Expect = 8e-05
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 6/77 (7%)
Query: 288 NIPGHTGTGWC------IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFG 341
N + +GW +++ L P + + L +L P+G + + K I D TNKCKG+G
Sbjct: 47 NSSSSSNSGWDQLSKTNLYIRGLPPHTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYG 106
Query: 342 FVTMTNYDEAAMAIASL 358
FV + A A+++L
Sbjct: 107 FVDFDSPAAAQKAVSAL 123
Score = 37.0 bits (84), Expect = 0.029
Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+++ NL DE L + PFG V + +++RD ++ +G GF M + ++ I
Sbjct: 143 LYISNLPLSMDEQELENMLKPFGQVISTRILRD-SSGTSRGVGFARMESTEKCEAVIGHF 201
Query: 359 NG 360
NG
Sbjct: 202 NG 203
>gi|51317355 RNA binding motif, single stranded interacting protein
3 isoform 1 [Homo sapiens]
Length = 437
Score = 113 bits (283), Expect = 2e-25
Identities = 75/213 (35%), Positives = 110/213 (51%), Gaps = 23/213 (10%)
Query: 10 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 69
P P++N+S+ SSNN + SKTNL + LP T ++ L
Sbjct: 34 PMAPPSPSTNSSSNNSSNN---------SSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPY 84
Query: 70 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 129
G+I S K + DK T Q GYGFV++ P A+KA+ +L +Q + K P+
Sbjct: 85 GKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT---- 140
Query: 130 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 189
NLY+S LP +M ++ELE + +G +I++RIL D GVSRGVGF R + + E
Sbjct: 141 ---NLYISNLPISMDEQELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVV 196
Query: 190 IKGLNG---QKPSG---ATEPITVKFANNPSQK 216
I+ NG + P G +EP+ KFA+ +K
Sbjct: 197 IQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKK 229
Score = 50.4 bits (119), Expect = 3e-06
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 263 PVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGA 322
P P PP SP T + ++ N G + +++ L P + + L +L P+G
Sbjct: 30 PAPHPMAPP--SPST-NSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGK 86
Query: 323 VNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+ + K I D NTN+CKG+GFV + A A+ASL
Sbjct: 87 IVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASL 122
Score = 37.4 bits (85), Expect = 0.023
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+++ NL DE L + PFG V + +++RD N +G GF M + ++ + I
Sbjct: 142 LYISNLPISMDEQELENMLKPFGHVISTRILRDAN-GVSRGVGFARMESTEKCEVVIQHF 200
Query: 359 NG 360
NG
Sbjct: 201 NG 202
>gi|51317353 RNA binding motif, single stranded interacting protein
3 isoform 3 [Homo sapiens]
Length = 419
Score = 113 bits (283), Expect = 2e-25
Identities = 75/213 (35%), Positives = 110/213 (51%), Gaps = 23/213 (10%)
Query: 10 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 69
P P++N+S+ SSNN + SKTNL + LP T ++ L
Sbjct: 33 PMAPPSPSTNSSSNNSSNN---------SSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPY 83
Query: 70 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 129
G+I S K + DK T Q GYGFV++ P A+KA+ +L +Q + K P+
Sbjct: 84 GKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT---- 139
Query: 130 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 189
NLY+S LP +M ++ELE + +G +I++RIL D GVSRGVGF R + + E
Sbjct: 140 ---NLYISNLPISMDEQELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVV 195
Query: 190 IKGLNG---QKPSG---ATEPITVKFANNPSQK 216
I+ NG + P G +EP+ KFA+ +K
Sbjct: 196 IQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKK 228
Score = 50.4 bits (119), Expect = 3e-06
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 263 PVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGA 322
P P PP SP T + ++ N G + +++ L P + + L +L P+G
Sbjct: 29 PAPHPMAPP--SPST-NSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGK 85
Query: 323 VNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+ + K I D NTN+CKG+GFV + A A+ASL
Sbjct: 86 IVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASL 121
Score = 37.4 bits (85), Expect = 0.023
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+++ NL DE L + PFG V + +++RD N +G GF M + ++ + I
Sbjct: 141 LYISNLPISMDEQELENMLKPFGHVISTRILRDAN-GVSRGVGFARMESTEKCEVVIQHF 199
Query: 359 NG 360
NG
Sbjct: 200 NG 201
>gi|51317351 RNA binding motif, single stranded interacting protein
3 isoform 2 [Homo sapiens]
Length = 420
Score = 113 bits (283), Expect = 2e-25
Identities = 75/213 (35%), Positives = 110/213 (51%), Gaps = 23/213 (10%)
Query: 10 PQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSI 69
P P++N+S+ SSNN + SKTNL + LP T ++ L
Sbjct: 34 PMAPPSPSTNSSSNNSSNN---------SSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPY 84
Query: 70 GEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASI 129
G+I S K + DK T Q GYGFV++ P A+KA+ +L +Q + K P+
Sbjct: 85 GKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPT---- 140
Query: 130 RDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEA 189
NLY+S LP +M ++ELE + +G +I++RIL D GVSRGVGF R + + E
Sbjct: 141 ---NLYISNLPISMDEQELENMLKPFGHVISTRILRD-ANGVSRGVGFARMESTEKCEVV 196
Query: 190 IKGLNG---QKPSG---ATEPITVKFANNPSQK 216
I+ NG + P G +EP+ KFA+ +K
Sbjct: 197 IQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKK 229
Score = 50.4 bits (119), Expect = 3e-06
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Query: 263 PVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGA 322
P P PP SP T + ++ N G + +++ L P + + L +L P+G
Sbjct: 30 PAPHPMAPP--SPST-NSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGK 86
Query: 323 VNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+ + K I D NTN+CKG+GFV + A A+ASL
Sbjct: 87 IVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASL 122
Score = 37.4 bits (85), Expect = 0.023
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+++ NL DE L + PFG V + +++RD N +G GF M + ++ + I
Sbjct: 142 LYISNLPISMDEQELENMLKPFGHVISTRILRDAN-GVSRGVGFARMESTEKCEVVIQHF 200
Query: 359 NG 360
NG
Sbjct: 201 NG 202
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 108 bits (271), Expect = 6e-24
Identities = 89/377 (23%), Positives = 163/377 (43%), Gaps = 58/377 (15%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 200
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
Query: 201 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQA----Q 242
T F +S + L SQ + + PN + G H A +
Sbjct: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
Query: 243 RFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 302
+ V R + +F + + ++ G+N +++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN----------LYIK 299
Query: 303 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 362
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
Query: 363 LGDRVLQVSFKTNKAHK 379
+G + L V+ K +
Sbjct: 358 VGSKPLYVALAQRKEER 374
Score = 80.1 bits (196), Expect = 3e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
Query: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
Query: 208 KFANNPSQKSS 218
A ++ +
Sbjct: 366 ALAQRKEERKA 376
Score = 46.2 bits (108), Expect = 5e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
Query: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
NG L DR + V FK+ K ++
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 108 bits (271), Expect = 6e-24
Identities = 89/377 (23%), Positives = 163/377 (43%), Gaps = 58/377 (15%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 200
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
Query: 201 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQA----Q 242
T F +S + L SQ + + PN + G H A +
Sbjct: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
Query: 243 RFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 302
+ V R + +F + + ++ G+N +++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN----------LYIK 299
Query: 303 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 362
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
Query: 363 LGDRVLQVSFKTNKAHK 379
+G + L V+ K +
Sbjct: 358 VGSKPLYVALAQRKEER 374
Score = 80.1 bits (196), Expect = 3e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
Query: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
Query: 208 KFANNPSQKSS 218
A ++ +
Sbjct: 366 ALAQRKEERKA 376
Score = 46.2 bits (108), Expect = 5e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
Query: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
NG L DR + V FK+ K ++
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 108 bits (271), Expect = 6e-24
Identities = 89/377 (23%), Positives = 163/377 (43%), Gaps = 58/377 (15%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
+L V L ++T+ F G + S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 12 SLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
+N ++ K I++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 72 MNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ------------------------KPSG 200
D+ S+G F+ F+ + A++AI+ +NG K
Sbjct: 132 CDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
Query: 201 ATEPITVKFANNPSQKSSQALLSQ--------LYQSPNRRYPG------PLHHQA----Q 242
T F +S + L SQ + + PN + G H A +
Sbjct: 190 FTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVE 249
Query: 243 RFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 302
+ V R + +F + + ++ G+N +++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVN----------LYIK 299
Query: 303 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 362
NL D+ L + F PFG++ + KV+ + KGFGFV ++ +EA A+ +NG
Sbjct: 300 NLDDTIDDEKLRKEFSPFGSITSAKVM--LEDGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
Query: 363 LGDRVLQVSFKTNKAHK 379
+G + L V+ K +
Sbjct: 358 VGSKPLYVALAQRKEER 374
Score = 80.1 bits (196), Expect = 3e-15
Identities = 51/191 (26%), Positives = 94/191 (49%), Gaps = 23/191 (12%)
Query: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
TN+ + + + E + LF G+ S K++RD G+S G+GFV+Y +DA KA+
Sbjct: 191 TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVE 249
Query: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
+NG + K I V A+ + + NLY+ L T+ ++
Sbjct: 250 EMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEK 309
Query: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ ++P+ V
Sbjct: 310 LRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEMNGR--IVGSKPLYV 365
Query: 208 KFANNPSQKSS 218
A ++ +
Sbjct: 366 ALAQRKEERKA 376
Score = 46.2 bits (108), Expect = 5e-05
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+F+ NL D L+ F FG + + KV+ D N KG+ FV + A AI +
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYAFVHFETQEAADKAIEKM 158
Query: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
NG L DR + V FK+ K ++
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181
>gi|4506449 RNA binding motif, single stranded interacting protein 2
[Homo sapiens]
Length = 407
Score = 107 bits (266), Expect = 2e-23
Identities = 73/230 (31%), Positives = 114/230 (49%), Gaps = 28/230 (12%)
Query: 2 VMIISTMEPQVSNGPTSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEE 61
V + M P + T N+S+G + N++ SKTNL + L T ++
Sbjct: 25 VSLAQQMAPPSPSNSTPNSSSGSNGNDQL-------------SKTNLYIRGLQPGTTDQD 71
Query: 62 FRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSY 121
L G+I S K + DK T + GYGFV++ P A+KA+ L +Q + K
Sbjct: 72 LVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQMAKQQE 131
Query: 122 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 181
P+ NLY+S LP +M ++ELE + +G++I++RIL D +G SRGVGF R +
Sbjct: 132 QDPT-------NLYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARME 183
Query: 182 KRIEAEEAIKGLNG---QKPSGA---TEPITVKFAN-NPSQKSSQALLSQ 224
+ E I NG + P G ++P+ KFA+ P ++ +Q Q
Sbjct: 184 STEKCEAIITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQ 233
Score = 45.8 bits (107), Expect = 6e-05
Identities = 21/60 (35%), Positives = 34/60 (56%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+++ L P + + L +L P+G + + K I D TNKCKG+GFV + A A+ +L
Sbjct: 58 LYIRGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTAL 117
Score = 35.4 bits (80), Expect = 0.086
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+++ NL DE L + PFG V + +++RD + +G GF M + ++ I
Sbjct: 137 LYISNLPLSMDEQELEGMLKPFGQVISTRILRD-TSGTSRGVGFARMESTEKCEAIITHF 195
Query: 359 NG 360
NG
Sbjct: 196 NG 197
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 105 bits (263), Expect = 5e-23
Identities = 86/341 (25%), Positives = 155/341 (45%), Gaps = 74/341 (21%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
N+ + L ++ + F + G I SCK+ D+ S G+GFV++ + A++AINT
Sbjct: 100 NIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDE--HGSRGFGFVHFETHEAAQQAINT 157
Query: 107 LNGLRLQTKTIKVSY--------ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 158
+NG+ L + + V + A + ++ N+YV LP + ++ L+ LFSQ+G++
Sbjct: 158 MNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKM 217
Query: 159 ITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSS 218
++ +++ D +G SR GF+ F+K EA++A+ +NG ++ S
Sbjct: 218 LSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHMNG-------------------KEVS 257
Query: 219 QALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPITI 278
LL Y G + +R +KR RF +
Sbjct: 258 GRLL----------YAGRAQKRVERQN---------ELKR-------------RFEQMKQ 285
Query: 279 DGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCK 338
D + G+N+ +V NL D+ L + F P+G + + KV+ + +K
Sbjct: 286 DRLRRYQGVNL----------YVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGGHSK-- 333
Query: 339 GFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTNKAHK 379
GFGFV ++ +EA A+ +NG +G + L V+ K +
Sbjct: 334 GFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEER 374
Score = 82.4 bits (202), Expect = 6e-16
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
+L V L ++T+ F G I S ++ RD T +SLGY ++N+ P DAE+A++T
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDT 71
Query: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
+N L+ + I++ +++ P N+++ L ++ K L FS +G I++ ++
Sbjct: 72 MNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVA 131
Query: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
D+ SRG GF+ F+ A++AI +NG
Sbjct: 132 CDE--HGSRGFGFVHFETHEAAQQAINTMNG 160
Score = 77.0 bits (188), Expect = 3e-14
Identities = 65/253 (25%), Positives = 116/253 (45%), Gaps = 31/253 (12%)
Query: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
TN+ V LP ++ ++ + LF G++ S K++RD +G S +GFVN+ ++A+KA+
Sbjct: 191 TNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVV 249
Query: 106 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 147
+NG + + + A + + NLYV L ++ +
Sbjct: 250 HMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDK 309
Query: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
L + FS YG I +++++ + G S+G GF+ F EA +A+ +NG+ T+P+ V
Sbjct: 310 LRKEFSPYGVITSAKVMTE--GGHSKGFGFVCFSSPEEATKAVTEMNGR--IVGTKPLYV 365
Query: 208 KFANNPSQKSSQALLSQLYQ---SPNRRYPGPL---HHQAQRFRLDNLLNMAYGVKRLMS 261
A ++ +A+L+ Y S R PL Q + L +
Sbjct: 366 ALAQRKEER--KAILTNQYMQRLSTMRTLSNPLLGSFQQPSSYFLPAMPQPPAQAAYYGC 423
Query: 262 GPVPPSACPPRFS 274
GPV P+ PR++
Sbjct: 424 GPVTPTQPAPRWT 436
Score = 46.2 bits (108), Expect = 5e-05
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
IF+ NL D L+ F FG + + KV D + ++ GFGFV ++ A AI ++
Sbjct: 101 IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHGSR--GFGFVHFETHEAAQQAINTM 158
Query: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
NG L DR + V FK+ + ++
Sbjct: 159 NGMLLNDRKVFVGHFKSRREREA 181
Score = 42.0 bits (97), Expect = 0.001
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
Query: 293 TGTGW---CIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 349
+G+G+ ++V +L PD E++L++ F P G + +++V RD T + G+ ++
Sbjct: 4 SGSGYPLASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPA 63
Query: 350 EAAMAIASLN 359
+A A+ ++N
Sbjct: 64 DAERALDTMN 73
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 104 bits (259), Expect = 2e-22
Identities = 89/377 (23%), Positives = 162/377 (42%), Gaps = 58/377 (15%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
+L V L ++T+ F G I S ++ RD IT +SLGY +VN+ P DAE+A++T
Sbjct: 12 SLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDT 71
Query: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
+N ++ K +++ +++ PS N+++ L K++ K L FS +G I++ +++
Sbjct: 72 MNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKG-----LNGQKP---------------SGATEP 204
D+ S+G GF+ F+ + AE AI+ LN +K +
Sbjct: 132 CDE--NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKE 189
Query: 205 ITVKFANNPSQKSSQALLSQLY-----------------QSPNRRYPGPLHHQAQRFRLD 247
T + N + L L+ +S + H+ + +D
Sbjct: 190 FTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVD 249
Query: 248 NLLNMAYGVKRLMSGPVPPSA-----CPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVY 302
+ K++ G +F + D +T G+N+ +V
Sbjct: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNL----------YVK 299
Query: 303 NLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYR 362
NL D+ L + F PFG + + KV+ + + KGFGFV ++ +EA A+ +NG
Sbjct: 300 NLDDGIDDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRI 357
Query: 363 LGDRVLQVSFKTNKAHK 379
+ + L V+ K +
Sbjct: 358 VATKPLYVALAQRKEER 374
Score = 83.2 bits (204), Expect = 4e-16
Identities = 61/213 (28%), Positives = 105/213 (49%), Gaps = 28/213 (13%)
Query: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
TN+ + ++M E + LFG G S K++ D+ +G+S G+GFV++ +DA+KA++
Sbjct: 191 TNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVD 249
Query: 106 TLNGLRLQTKTIKVSYARPS------------------SASIRDANLYVSGLPKTMTQKE 147
+NG L K I V A+ + NLYV L + +
Sbjct: 250 EMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDER 309
Query: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITV 207
L + FS +G I +++++++ G S+G GF+ F EA +A+ +NG+ AT+P+ V
Sbjct: 310 LRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGR--IVATKPLYV 365
Query: 208 KFANNPSQKSSQALLSQLY---QSPNRRYPGPL 237
A ++ QA L+ Y + R P P+
Sbjct: 366 ALAQRKEER--QAHLTNQYMQRMASVRAVPNPV 396
Score = 49.3 bits (116), Expect = 6e-06
Identities = 30/83 (36%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
IF+ NL D L+ F FG + + KV+ D N KG+GFV + A AI +
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCD--ENGSKGYGFVHFETQEAAERAIEKM 158
Query: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
NG L DR + V FK+ K ++
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA 181
Score = 45.4 bits (106), Expect = 8e-05
Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 124 PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKR 183
PS+ S A+LYV L +T+ L + FS G I++ R+ D +T S G ++ F +
Sbjct: 3 PSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQP 62
Query: 184 IEAEEAIKGLNGQKPSGATEPITVKFA-NNPSQKSS 218
+AE A+ +N G +P+ + ++ +PS + S
Sbjct: 63 ADAERALDTMNFDVIKG--KPVRIMWSQRDPSLRKS 96
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 101 bits (252), Expect = 1e-21
Identities = 82/332 (24%), Positives = 146/332 (43%), Gaps = 69/332 (20%)
Query: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
Query: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 157
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +GR
Sbjct: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGR 120
Query: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
I +R++ D TG S+G GF+ F + +AE AI+ + GQ G P+ KS
Sbjct: 121 ISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKS 180
Query: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPIT 277
+ Y+S ++ D ++N + PS C +T
Sbjct: 181 T-------YES-----------NTKQLSYDEVVNQS-----------SPSNCTVYCGGVT 211
Query: 278 IDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKC 337
G+T E ++ Q F PFG + ++V D
Sbjct: 212 -SGLT---------------------------EQLMRQTFSPFGQIMEIRVFPD------ 237
Query: 338 KGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 369
KG+ FV +++ AA AI S+NG + V++
Sbjct: 238 KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269
Score = 58.9 bits (141), Expect = 7e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 293 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 352
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 91 TSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAE 150
Query: 353 MAIASLNGYRLGDRVLQVSFKTNK 376
AI + G LG R ++ ++ T K
Sbjct: 151 NAIQQMGGQWLGGRQIRTNWATRK 174
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
++V NLS D E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
Query: 359 NGYRLGDRVLQVSFKT 374
NG ++ + ++V++ T
Sbjct: 67 NGRKIMGKEVKVNWAT 82
Score = 32.0 bits (71), Expect = 0.95
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 57 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 116
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 214 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 267
Query: 117 IKVSYAR 123
+K + +
Sbjct: 268 VKCYWGK 274
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 100 bits (250), Expect = 2e-21
Identities = 74/332 (22%), Positives = 144/332 (43%), Gaps = 69/332 (20%)
Query: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
D L V L +++T+ LF IG +SCK++ + + Y FV + + +DA
Sbjct: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEHRDAA 62
Query: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKTMTQKELEQLFSQYGR 157
A+ +NG ++ K +KV++A S+ +D +++V L +T ++++ F+ +G+
Sbjct: 63 AALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGK 122
Query: 158 IITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKS 217
I +R++ D TG S+G GF+ F +++AE AI + GQ G P+ KS
Sbjct: 123 ISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKS 182
Query: 218 SQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSPIT 277
+Q + ++ R ++++N + P C
Sbjct: 183 TQ------------------ENNTKQLRFEDVVNQS-----------SPKNC-------- 205
Query: 278 IDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKC 337
++ ++ + ++ Q F PFG + ++V +
Sbjct: 206 --------------------TVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPE------ 239
Query: 338 KGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 369
KG+ FV + ++ AA AI S+NG + V++
Sbjct: 240 KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 271
Score = 59.3 bits (142), Expect = 6e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 293 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 352
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 93 TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 152
Query: 353 MAIASLNGYRLGDRVLQVSFKTNK 376
AI + G LG R ++ ++ T K
Sbjct: 153 NAIVHMGGQWLGGRQIRTNWATRK 176
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/76 (30%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
++V NLS D E ++ QLF G + K+I + +N + FV + +AA A+A++
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSN--DPYCFVEFYEHRDAAAALAAM 68
Query: 359 NGYRLGDRVLQVSFKT 374
NG ++ + ++V++ T
Sbjct: 69 NGRKILGKEVKVNWAT 84
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 53 LPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 112
+ +T + R F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 212 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 265
Query: 113 QTKTIKVSYARPS 125
+ +K + + S
Sbjct: 266 EGHVVKCYWGKES 278
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 97.4 bits (241), Expect = 2e-20
Identities = 82/343 (23%), Positives = 146/343 (42%), Gaps = 80/343 (23%)
Query: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAE 101
D+ L V L +++T+ LF IG ++CK++ D T + Y FV + + + A
Sbjct: 3 DEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAA 60
Query: 102 KAINTLNGLRLQTKTIKVSYARPSSASIRDA---------------NLYVSGLPKTMTQK 146
A+ +NG ++ K +KV++A S+ +D +++V L +T +
Sbjct: 61 AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTE 120
Query: 147 ELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPIT 206
+++ F+ +GRI +R++ D TG S+G GF+ F + +AE AI+ + GQ G
Sbjct: 121 DIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTN 180
Query: 207 VKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPP 266
P+ KS+ Y+S ++ D ++N + P
Sbjct: 181 WATRKPPAPKST-------YES-----------NTKQLSYDEVVNQS-----------SP 211
Query: 267 SACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNV 326
S C +T G+T E ++ Q F PFG + +
Sbjct: 212 SNCTVYCGGVT-SGLT---------------------------EQLMRQTFSPFGQIMEI 243
Query: 327 KVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 369
+V D KG+ FV +++ AA AI S+NG + V++
Sbjct: 244 RVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
Score = 82.8 bits (203), Expect = 5e-16
Identities = 54/204 (26%), Positives = 92/204 (45%), Gaps = 28/204 (13%)
Query: 19 NTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLV 78
N + PSS ++ S ++ V L +T E+ ++ F G I ++V
Sbjct: 79 NWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 138
Query: 79 RDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYAR---PSSASIRDAN-- 133
+D TG+S GYGFV++ + DAE AI + G L + I+ ++A P+ S ++N
Sbjct: 139 KDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198
Query: 134 -----------------LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVG 176
+Y G+ +T++ + Q FS +G+I+ R+ D +G
Sbjct: 199 QLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYS 252
Query: 177 FIRFDKRIEAEEAIKGLNGQKPSG 200
F+RF+ A AI +NG G
Sbjct: 253 FVRFNSHESAAHAIVSVNGTTIEG 276
Score = 58.5 bits (140), Expect = 9e-09
Identities = 28/78 (35%), Positives = 46/78 (58%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A AI +
Sbjct: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
Query: 359 NGYRLGDRVLQVSFKTNK 376
G LG R ++ ++ T K
Sbjct: 168 GGQWLGGRQIRTNWATRK 185
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
++V NLS D E+++ QLF G N K+I D N + FV + AA A+A++
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGN--DPYCFVEFHEHRHAAAALAAM 66
Query: 359 NGYRLGDRVLQVSFKT 374
NG ++ + ++V++ T
Sbjct: 67 NGRKIMGKEVKVNWAT 82
Score = 32.0 bits (71), Expect = 0.95
Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 57 MTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKT 116
+T++ R F G+I ++ DK GY FV + + A AI ++NG ++
Sbjct: 225 LTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSVNGTTIEGHV 278
Query: 117 IKVSYAR 123
+K + +
Sbjct: 279 VKCYWGK 285
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 96.3 bits (238), Expect = 4e-20
Identities = 76/347 (21%), Positives = 147/347 (42%), Gaps = 82/347 (23%)
Query: 42 DDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRD----KITGQSLG--------- 88
D L V L +++T+ LF IG +SCK++ + + S+G
Sbjct: 5 DGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSN 64
Query: 89 --YGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIRDA----NLYVSGLPKT 142
Y FV + + +DA A+ +NG ++ K +KV++A S+ +D +++V L
Sbjct: 65 DPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPE 124
Query: 143 MTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGAT 202
+T ++++ F+ +G+I +R++ D TG S+G GF+ F +++AE AI + GQ G
Sbjct: 125 ITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQ 184
Query: 203 EPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSG 262
P+ KS+Q + ++ R ++++N +
Sbjct: 185 IRTNWATRKPPAPKSTQ------------------ENNTKQLRFEDVVNQS--------- 217
Query: 263 PVPPSACPPRFSPITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGA 322
P C ++ ++ + ++ Q F PFG
Sbjct: 218 --SPKNC----------------------------TVYCGGIASGLTDQLMRQTFSPFGQ 247
Query: 323 VNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQ 369
+ ++V + KG+ FV + ++ AA AI S+NG + V++
Sbjct: 248 IMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 288
Score = 59.3 bits (142), Expect = 6e-09
Identities = 29/84 (34%), Positives = 48/84 (57%)
Query: 293 TGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAA 352
T + +FV +LSP+ + F PFG +++ +V++D T K KG+GFV+ N +A
Sbjct: 110 TSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAE 169
Query: 353 MAIASLNGYRLGDRVLQVSFKTNK 376
AI + G LG R ++ ++ T K
Sbjct: 170 NAIVHMGGQWLGGRQIRTNWATRK 193
Score = 35.0 bits (79), Expect = 0.11
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 15/91 (16%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRD----FNTNKCKGFG-----------FV 343
++V NLS D E ++ QLF G + K+I + N GF FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 344 TMTNYDEAAMAIASLNGYRLGDRVLQVSFKT 374
+ +AA A+A++NG ++ + ++V++ T
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVNWAT 101
Score = 31.2 bits (69), Expect = 1.6
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 53 LPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRL 112
+ +T + R F G+I ++ +K GY FV + + A AI ++NG +
Sbjct: 229 IASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSVNGTTI 282
Query: 113 QTKTIKVSYARPS 125
+ +K + + S
Sbjct: 283 EGHVVKCYWGKES 295
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 90.5 bits (223), Expect = 2e-18
Identities = 51/151 (33%), Positives = 85/151 (56%), Gaps = 4/151 (2%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
+L V L +T+ F G I S ++ RDKIT +SLGY +VNY P DA++A+ T
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
LN ++ + +++ +++ PS N+++ L KT+ K L +FS +G I++ ++
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
D+ +G GF+ F K+ AE AI +NG
Sbjct: 123 CDEKG--PKGYGFVHFQKQESAERAIDVMNG 151
Score = 43.1 bits (100), Expect = 4e-04
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 2/73 (2%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
N+ + L + + + ++F + G I SCK+ D+ + GYGFV++ + AE+AI+
Sbjct: 91 NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPK--GYGFVHFQKQESAERAIDV 148
Query: 107 LNGLRLQTKTIKV 119
+NG+ L + I V
Sbjct: 149 MNGMFLNYRKIFV 161
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+F+ NL D L+ +F FG + + KV D KG+GFV + A AI +
Sbjct: 92 VFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGPKGYGFVHFQKQESAERAIDVM 149
Query: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
NG L R + V FK++K ++
Sbjct: 150 NGMFLNYRKIFVGRFKSHKEREA 172
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 90.5 bits (223), Expect = 2e-18
Identities = 51/151 (33%), Positives = 85/151 (56%), Gaps = 4/151 (2%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
+L V L +T+ F G I S ++ RDKIT +SLGY +VNY P DA++A+ T
Sbjct: 3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALET 62
Query: 107 LNGLRLQTKTIKVSYAR--PSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
LN ++ + +++ +++ PS N+++ L KT+ K L +FS +G I++ ++
Sbjct: 63 LNFDVIKGRPVRIMWSQRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVA 122
Query: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNG 195
D+ +G GF+ F K+ AE AI +NG
Sbjct: 123 CDEKG--PKGYGFVHFQKQESAERAIDVMNG 151
Score = 43.1 bits (100), Expect = 4e-04
Identities = 23/73 (31%), Positives = 42/73 (57%), Gaps = 2/73 (2%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
N+ + L + + + ++F + G I SCK+ D+ + GYGFV++ + AE+AI+
Sbjct: 91 NVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKGPK--GYGFVHFQKQESAERAIDV 148
Query: 107 LNGLRLQTKTIKV 119
+NG+ L + I V
Sbjct: 149 MNGMFLNYRKIFV 161
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+F+ NL D L+ +F FG + + KV D KG+GFV + A AI +
Sbjct: 92 VFIKNLGKTIDNKALYNIFSAFGNILSCKVACD--EKGPKGYGFVHFQKQESAERAIDVM 149
Query: 359 NGYRLGDRVLQVS-FKTNKAHKS 380
NG L R + V FK++K ++
Sbjct: 150 NGMFLNYRKIFVGRFKSHKEREA 172
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 87.8 bits (216), Expect = 1e-17
Identities = 46/156 (29%), Positives = 95/156 (60%), Gaps = 4/156 (2%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
+L V L ++T++ F ++G + S ++ RD++T +SLGY +VN++ DA+KA++T
Sbjct: 11 SLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDT 70
Query: 107 LNGLRLQTKTIKVSYARPSSASIRD--ANLYVSGLPKTMTQKELEQLFSQYGRIITSRIL 164
+N ++ K+I++ +++ + R N+++ L K++ K L + FS +G+I++S+++
Sbjct: 71 MNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVM 130
Query: 165 VDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 200
D S+G F+ F + A+ AI+ +NG+ G
Sbjct: 131 SDDQG--SKGYAFVHFQNQSAADRAIEEMNGKLLKG 164
Score = 87.4 bits (215), Expect = 2e-17
Identities = 79/336 (23%), Positives = 147/336 (43%), Gaps = 80/336 (23%)
Query: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
N+ + L +++ + F + G+I S K++ D S GY FV++ + A++AI
Sbjct: 99 NVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEE 156
Query: 107 LNGLRLQTKTIKVSYARPSSASIRDA----------NLYVSGLPKTMTQKELEQLFSQYG 156
+NG L K KV R + R+A N+Y+ M + L+ +FS+YG
Sbjct: 157 MNGKLL--KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
Query: 157 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQK 216
+ ++ +++ D +G S+G GF+ FD A++A++ +NG+ +G + F +K
Sbjct: 215 KTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQ-----LIFVGRAQKK 268
Query: 217 -SSQALLSQLYQSPNRRYPGPLHHQAQRFRLDNLLNMAYGVKRLMSGPVPPSACPPRFSP 275
QA L Q+++ Q +R R+ GVK
Sbjct: 269 VERQAELKQMFE------------QLKRERIRG----CQGVK------------------ 294
Query: 276 ITIDGMTSLVGMNIPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTN 335
+++ NL D+ L F FG+++ VKV+++
Sbjct: 295 -----------------------LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQE--EG 329
Query: 336 KCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVS 371
+ KGFG + ++ ++A A+ +NG LG + L ++
Sbjct: 330 QSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIA 365
Score = 66.2 bits (160), Expect = 5e-11
Identities = 47/169 (27%), Positives = 79/169 (46%), Gaps = 21/169 (12%)
Query: 46 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 105
TN+ + +M E + +F G+ S K++ D +G+S G+GFV++ + A+KA+
Sbjct: 190 TNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVE 248
Query: 106 TLNGLRLQTKTIKVSYA------------------RPSSASIRDANLYVSGLPKTMTQKE 147
+NG + + I V A R + LY+ L T+ ++
Sbjct: 249 EMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEK 308
Query: 148 LEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQ 196
L FS +G I SR+ V Q G S+G G I F +A +A+ +NG+
Sbjct: 309 LRNEFSSFGSI--SRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGR 355
Score = 48.1 bits (113), Expect = 1e-05
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 48 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 107
L + L + E+ R+ F S G I K+++++ GQS G+G + + P+DA KA+ +
Sbjct: 295 LYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTEM 352
Query: 108 NGLRLQTKTIKVSYAR 123
NG L +K + ++ A+
Sbjct: 353 NGRILGSKPLSIALAQ 368
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+++ N D D+ L +F +G +VKV+ D ++ K KGFGFV+ +++ A A+ +
Sbjct: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEM 250
Query: 359 NGYRLGDRVLQVSFKTNKAHK 379
NG + +++ V K +
Sbjct: 251 NGRDINGQLIFVGRAQKKVER 271
Score = 42.4 bits (98), Expect = 7e-04
Identities = 24/69 (34%), Positives = 40/69 (57%)
Query: 126 SASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIE 185
+A R A+LYV L +T+ L + FS G +++ RI DQVT S G ++ F + +
Sbjct: 4 AAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLAD 63
Query: 186 AEEAIKGLN 194
A++A+ +N
Sbjct: 64 AQKALDTMN 72
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 3/79 (3%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
+F+ NL D L++ F FG + + KV+ D KG+ FV N A AI +
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSD--DQGSKGYAFVHFQNQSAADRAIEEM 157
Query: 359 NGYRL-GDRVLQVSFKTNK 376
NG L G +V FK K
Sbjct: 158 NGKLLKGCKVFVGRFKNRK 176
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 86.7 bits (213), Expect = 3e-17
Identities = 54/172 (31%), Positives = 92/172 (53%), Gaps = 4/172 (2%)
Query: 50 VNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTLNG 109
V L + +++ LF G + + + +D++TGQ GYGFV ++ +DA+ AI +N
Sbjct: 17 VGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIMNM 76
Query: 110 LRLQTKTIKVSYARPSSASIR-DANLYVSGLPKTMTQKELEQLFSQYGRII-TSRILVDQ 167
++L K I+V+ A + ++ AN+++ L + +K L FS +G I+ T +I+ D
Sbjct: 77 IKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDP 136
Query: 168 VTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQ 219
TG S+G FI F ++ AI+ +NGQ PITV +A K +
Sbjct: 137 DTGNSKGYAFINFASFDASDAAIEAMNGQYL--CNRPITVSYAFKKDSKGER 186
Score = 58.9 bits (141), Expect = 7e-09
Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAV-NNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIAS 357
IF+ NL P+ DE +L+ F FG + K++RD +T KG+ F+ ++D + AI +
Sbjct: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEA 161
Query: 358 LNGYRLGDRVLQVSFKTNKAHK 379
+NG L +R + VS+ K K
Sbjct: 162 MNGQYLCNRPITVSYAFKKDSK 183
Score = 52.8 bits (125), Expect = 5e-07
Identities = 33/90 (36%), Positives = 52/90 (57%), Gaps = 2/90 (2%)
Query: 122 ARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 181
A P S +DA +YV GL + +++ L +LF Q G ++ + + D+VTG +G GF+ F
Sbjct: 3 AGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFL 62
Query: 182 KRIEAEEAIKGLNGQKPSGATEPITVKFAN 211
+A+ AIK +N K G +PI V A+
Sbjct: 63 SEEDADYAIKIMNMIKLYG--KPIRVNKAS 90
Score = 40.4 bits (93), Expect = 0.003
Identities = 22/73 (30%), Positives = 40/73 (54%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
++V L E +LW+LF G V N + +D T + +G+GFV + ++A AI +
Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
Query: 359 NGYRLGDRVLQVS 371
N +L + ++V+
Sbjct: 75 NMIKLYGKPIRVN 87
>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
sapiens]
Length = 448
Score = 85.5 bits (210), Expect = 7e-17
Identities = 93/421 (22%), Positives = 169/421 (40%), Gaps = 64/421 (15%)
Query: 17 TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 76
+S S G + + P T D L + +P+N+ +++ + LF G+I
Sbjct: 25 SSPGSAGHMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELT 84
Query: 77 LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIR--DANL 134
+++D+ TG G F+ Y + + A KA + L+ + + +P+ + R D L
Sbjct: 85 VLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKL 144
Query: 135 YVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLN 194
+V L K ++ ++ +LF +G I IL G S+G F+++ EA+ AI L+
Sbjct: 145 FVGMLNKQQSEDDVRRLFEAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALH 203
Query: 195 G-QKPSGATEPITVKFANNPSQKS---------------------------SQALLSQLY 226
G Q GA+ + VKFA+ +++ +QAL+ Q
Sbjct: 204 GSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQA 263
Query: 227 QSPNRRYPGPLHHQAQRFRLDNLLNM-AYGVKRLMSGPVPPS---ACPPRFSPITIDGMT 282
G + F + M A + L + P+ P+ + PP + + +
Sbjct: 264 ALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIP 323
Query: 283 SLVGMNIPGHTG---------TGWCIFVYNLSPDSDESV------------LWQLFGP-- 319
S +G+N G TG +F + P +S + Q GP
Sbjct: 324 SPIGVN--GFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAA 381
Query: 320 ----FGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVLQVSFKTN 375
+G ++ + + GFV+ N A AI ++NG+++G + L+V K
Sbjct: 382 YPAAYGQISQAFPQPPPMIPQQQREGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRP 441
Query: 376 K 376
K
Sbjct: 442 K 442
Score = 35.8 bits (81), Expect = 0.066
Identities = 15/39 (38%), Positives = 24/39 (61%)
Query: 90 GFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSAS 128
GFV++ +P A+ AI +NG ++ K +KV RP A+
Sbjct: 407 GFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDAN 445
>gi|4505255 musashi 1 [Homo sapiens]
Length = 362
Score = 83.2 bits (204), Expect = 4e-16
Identities = 45/156 (28%), Positives = 77/156 (49%), Gaps = 5/156 (3%)
Query: 30 NCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGY 89
+ P P + + + L TQE R FG GE++ C ++RD +T +S G+
Sbjct: 4 DAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGF 63
Query: 90 GFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSAS----IRDANLYVSGLPKTMTQ 145
GFV ++D +K + + L +KTI A P A R ++V GL T
Sbjct: 64 GFVTFMDQAGVDKVL-AQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTV 122
Query: 146 KELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFD 181
++++Q F Q+G++ + ++ D+ T RG GF+ F+
Sbjct: 123 EDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFE 158
Score = 37.4 bits (85), Expect = 0.023
Identities = 18/71 (25%), Positives = 35/71 (49%)
Query: 134 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 193
+++ GL TQ+ L + F Q+G + ++ D +T SRG GF+ F + ++ +
Sbjct: 22 MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQS 81
Query: 194 NGQKPSGATEP 204
+ S +P
Sbjct: 82 RHELDSKTIDP 92
Score = 37.4 bits (85), Expect = 0.023
Identities = 19/46 (41%), Positives = 27/46 (58%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVT 344
+F+ LS + + L + FG FG V V+RD T + +GFGFVT
Sbjct: 22 MFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVT 67
Score = 37.4 bits (85), Expect = 0.023
Identities = 20/51 (39%), Positives = 30/51 (58%)
Query: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYD 349
IFV LS ++ + Q F FG V++ ++ D TN+ +GFGFVT + D
Sbjct: 111 IFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESED 161
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,422,071
Number of Sequences: 37866
Number of extensions: 670318
Number of successful extensions: 3544
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 218
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 2139
Number of HSP's gapped (non-prelim): 1035
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.