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Search of human proteins with 221139728
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221139728 pleckstrin homology domain containing, family M
(with RUN domain) member 2 [Homo sapiens]
(1019 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221139728 pleckstrin homology domain containing, family M (wi... 2077 0.0
gi|40538728 pleckstrin homology domain containing, family M (wit... 69 2e-11
gi|116292170 RUN domain containing 2A [Homo sapiens] 63 1e-09
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 51 6e-06
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 50 8e-06
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 50 8e-06
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 50 8e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 50 1e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 50 1e-05
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 48 5e-05
gi|221307580 RUN domain containing 3A isoform 3 [Homo sapiens] 47 1e-04
gi|197304746 RUN domain containing 3B isoform c [Homo sapiens] 47 1e-04
gi|197304744 RUN domain containing 3B isoform b [Homo sapiens] 47 1e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 45 3e-04
gi|221307578 RUN domain containing 3A isoform 1 [Homo sapiens] 45 3e-04
gi|5730015 RUN domain containing 3A isoform 2 [Homo sapiens] 45 3e-04
gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo ... 45 3e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 44 6e-04
gi|21328446 hormone-sensitive lipase [Homo sapiens] 42 0.002
gi|7662352 RUN and FYVE domain containing 3 isoform 2 [Homo sapi... 42 0.002
gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo sap... 42 0.002
gi|195220720 RUN and FYVE domain containing 3 isoform 3 [Homo sa... 42 0.002
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 42 0.002
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 42 0.003
gi|66932943 variable charge, X chromosome [Homo sapiens] 42 0.004
gi|19923090 RUN domain containing 3B isoform a [Homo sapiens] 41 0.005
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens] 41 0.007
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 41 0.007
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 40 0.009
gi|48762947 variable charge, X-linked 3A [Homo sapiens] 40 0.011
>gi|221139728 pleckstrin homology domain containing, family M (with
RUN domain) member 2 [Homo sapiens]
Length = 1019
Score = 2077 bits (5382), Expect = 0.0
Identities = 1019/1019 (100%), Positives = 1019/1019 (100%)
Query: 1 MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDL 60
MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDL
Sbjct: 1 MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDL 60
Query: 61 SSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLL 120
SSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLL
Sbjct: 61 SSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLL 120
Query: 121 HKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFED 180
HKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFED
Sbjct: 121 HKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFED 180
Query: 181 RLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGD 240
RLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGD
Sbjct: 181 RLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGD 240
Query: 241 LTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQA 300
LTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQA
Sbjct: 241 LTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQA 300
Query: 301 LDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSL 360
LDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSL
Sbjct: 301 LDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSL 360
Query: 361 GRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQ 420
GRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQ
Sbjct: 361 GRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQ 420
Query: 421 LDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGG 480
LDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGG
Sbjct: 421 LDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGG 480
Query: 481 HHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVS 540
HHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVS
Sbjct: 481 HHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVS 540
Query: 541 EPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHV 600
EPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHV
Sbjct: 541 EPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHLLLLMIHV 600
Query: 601 FRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDY 660
FRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDY
Sbjct: 601 FRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDY 660
Query: 661 VSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATM 720
VSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATM
Sbjct: 661 VSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATM 720
Query: 721 EKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHY 780
EKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHY
Sbjct: 721 EKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHY 780
Query: 781 KAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHA 840
KAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHA
Sbjct: 781 KAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHA 840
Query: 841 FQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFT 900
FQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFT
Sbjct: 841 FQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFT 900
Query: 901 CHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDR 960
CHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDR
Sbjct: 901 CHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDR 960
Query: 961 LLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC 1019
LLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC
Sbjct: 961 LLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC 1019
>gi|40538728 pleckstrin homology domain containing, family M (with
RUN domain) member 1 [Homo sapiens]
Length = 1056
Score = 69.3 bits (168), Expect = 2e-11
Identities = 56/211 (26%), Positives = 92/211 (43%), Gaps = 31/211 (14%)
Query: 17 SVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQD----LSSG--------- 63
SVK LQ + + + + + D +C L+ ++GL +G
Sbjct: 25 SVKALQKQYVSLDT---VVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKSAHQ 81
Query: 64 -------YWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQEN 116
+W L+ T + I ++E L V T++GR RAWL LALN+ +E YL+L +
Sbjct: 82 KPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQE 141
Query: 117 LGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLD---LAPYMPDYYKPQ 173
LH+YY AL+ + L+ + GL + FEL + L+ L P P
Sbjct: 142 QARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLALSGLCPL 201
Query: 174 YLLDFEDRLPSSVHGSDSLSLNSFNSVTSTN 204
LD P S G++ S +S++ ++
Sbjct: 202 SELD-----PLSTSGAELQRKESLDSISHSS 227
>gi|116292170 RUN domain containing 2A [Homo sapiens]
Length = 375
Score = 63.2 bits (152), Expect = 1e-09
Identities = 41/145 (28%), Positives = 72/145 (49%), Gaps = 9/145 (6%)
Query: 64 YWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKY 123
+W V + +++ L+H+A+++GR RAWL ALNE+SLE YL + + L +
Sbjct: 86 FWYYVKEVLNKHELQRFYSLRHIASDVGRGRAWLRCALNEHSLERYLHMLLADRCRLSTF 145
Query: 124 YVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLD----LAPYMPDYYKPQYLLDFE 179
Y + V + ++ T+ +GL I F +++D L+ AP + D K + +
Sbjct: 146 YEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLK-ESTQNVT 204
Query: 180 DRLPSSVHGSDSLSLNSFNSVTSTN 204
L S G SL F +T+++
Sbjct: 205 SLLKESTQGVSSL----FREITASS 225
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 50.8 bits (120), Expect = 6e-06
Identities = 66/326 (20%), Positives = 116/326 (35%), Gaps = 20/326 (6%)
Query: 227 AVPSVPSTDWEDGDLTDTVSGPRSTASDLT--SSKASTRSPTQ--RQNPFNEEPAETVSS 282
A P + D D + P++ +T + KA T++P + R P SS
Sbjct: 159 APPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSS 218
Query: 283 SDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQ 342
S ++ ++ +EE A P + +V+ K + S E S Q
Sbjct: 219 SSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQ 278
Query: 343 KKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTS 402
KK K G + P ++ P ++ ESSE S E +S
Sbjct: 279 KKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSS-----DESDSSS 333
Query: 403 MERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPM 462
E P V+ + + P+ + + + +AP +P + +
Sbjct: 334 EEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAV 393
Query: 463 DFYRFTVESPSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTR 522
T +SP+ V P G GQ L + +++ EEE E + + + TT+
Sbjct: 394 -----TTKSPA-VKPAAAPKQPVGGGQKL-LTRKADSSSSEEESSSSEEEKTKKMVATTK 446
Query: 523 EAQELEAQLSLVREGPVSEPEPGTQE 548
+A LSL P + G+++
Sbjct: 447 PKATAKAALSL----PAKQAPQGSRD 468
Score = 32.3 bits (72), Expect = 2.3
Identities = 33/138 (23%), Positives = 54/138 (39%), Gaps = 17/138 (12%)
Query: 255 LTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIR 314
L S+K R Q P ++ + SSSD+ +S+E+EE Q A + +
Sbjct: 58 LKSAKVPERK-LQANGPVAKKAKKKASSSDS---EDSSEEEEEVQGPPAKKAAVPAKRVG 113
Query: 315 VTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLA-SPQ 373
+ K K +S S EE+S D + + P P A +P
Sbjct: 114 LPPGKAAAKASESSSSEESS------------DDDDEEDQKKQPVQKGVKPQAKAAKAPP 161
Query: 374 EEGEGPSSTTESSERSEP 391
++ + S ++SS EP
Sbjct: 162 KKAKSSDSDSDSSSEDEP 179
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 50.4 bits (119), Expect = 8e-06
Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 83 LQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTL 142
L + T +GR RAWLYLAL + L YL++ +N LL ++Y AL+ + + + + L
Sbjct: 89 LPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVI-VGL 147
Query: 143 VSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTS 202
+ GL + L L LD + D+ YL D +D H + L+ N V
Sbjct: 148 LVGLNVLDANLCLKGEDLDSQVGVIDF--SLYLKDVQDLDGGKEHERITDVLDQKNYVEE 205
Query: 203 TN 204
N
Sbjct: 206 LN 207
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 50.4 bits (119), Expect = 8e-06
Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 83 LQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTL 142
L + T +GR RAWLYLAL + L YL++ +N LL ++Y AL+ + + + + L
Sbjct: 89 LPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVI-VGL 147
Query: 143 VSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTS 202
+ GL + L L LD + D+ YL D +D H + L+ N V
Sbjct: 148 LVGLNVLDANLCLKGEDLDSQVGVIDF--SLYLKDVQDLDGGKEHERITDVLDQKNYVEE 205
Query: 203 TN 204
N
Sbjct: 206 LN 207
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 50.4 bits (119), Expect = 8e-06
Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 83 LQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTL 142
L + T +GR RAWLYLAL + L YL++ +N LL ++Y AL+ + + + + L
Sbjct: 197 LPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVI-VGL 255
Query: 143 VSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFEDRLPSSVHGSDSLSLNSFNSVTS 202
+ GL + L L LD + D+ YL D +D H + L+ N V
Sbjct: 256 LVGLNVLDANLCLKGEDLDSQVGVIDF--SLYLKDVQDLDGGKEHERITDVLDQKNYVEE 313
Query: 203 TN 204
N
Sbjct: 314 LN 315
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 50.1 bits (118), Expect = 1e-05
Identities = 95/403 (23%), Positives = 141/403 (34%), Gaps = 58/403 (14%)
Query: 208 DDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDTVSGPRSTASDLTSS---KASTRS 264
++S ++P E+ + P S P + E+ L+ P S A + S +AS S
Sbjct: 490 EESPLSPPPEE---SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS 546
Query: 265 PTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKK 324
P ++P + P E + +S S EE+ PP+ +
Sbjct: 547 PPFEESPLSPPPEE-LPTSPPPEASRLSPPPEESPMSPPPE------------------E 587
Query: 325 KKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSP---DTMLASPQEEGEGPSS 381
EAS L P + + + + P R SP D+ ++ P EE P S
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES--PMS 645
Query: 382 TTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGS 441
R P +P + S PLS ++ P SR PP + T
Sbjct: 646 PPPEVSRLSP---LPVVSRLSPPPEESPLSPPPEE--SPTSPPPEASRLSPPPEDSPTSP 700
Query: 442 PG-DAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAGLGQPLHV---PSSP 497
P D+P PP D L E P G H +P H+ P P
Sbjct: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEP-HLSPRPEEP 759
Query: 498 EAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQ 557
+ Q EE +P+P E E E LS EGP P+P +E+ + ++
Sbjct: 760 HLSPQAEE----PHLSPQPEEPCLCAVPE-EPHLSPQAEGPHLSPQP--EELHLSPQTEE 812
Query: 558 P-------SPCLSSAEDSGVDEGQGSPSEMVHSSEFRVDNNHL 593
P PCLS +E SP R + +HL
Sbjct: 813 PHLSPVPEEPCLSPQP----EESHLSPQSEEPCLSPRPEESHL 851
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 49.7 bits (117), Expect = 1e-05
Identities = 50/216 (23%), Positives = 90/216 (41%), Gaps = 8/216 (3%)
Query: 177 DFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSA-IAPSSEDYDFGDVFPAVPSVPSTD 235
D D SS + S S NS +S S + + DS+ + SS+ D D + S S+D
Sbjct: 946 DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005
Query: 236 WEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEK 295
D + S S +SD ++S S+ S + + + +++ SSD++ +S
Sbjct: 1006 SSDS----SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1061
Query: 296 EEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGD-GDSR 354
+ + + D D+ + ++ S ++S + + D DS
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 355 NGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSE 390
N S S DS D+ +S S ++ESS+ S+
Sbjct: 1122 NSSDS--SDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155
Score = 48.5 bits (114), Expect = 3e-05
Identities = 48/208 (23%), Positives = 92/208 (44%), Gaps = 6/208 (2%)
Query: 185 SVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDT 244
S + SDS S +S +S +S + + D S + SS D D + S S+D DG +D+
Sbjct: 797 SSNSSDS-SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDG--SDS 853
Query: 245 VSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTT--SQEKEEAQALD 302
S RS +S+ + S S+ S + + + E+ +SSD++ + S + + + D
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Query: 303 PPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGD-GDSRNGSPSLG 361
D+ + + S + ++S + + + D +S + S S
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 362 RDSPDTMLASPQEEGEGPSSTTESSERS 389
DS D+ +S + S +++SS+ S
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSS 1001
Score = 46.2 bits (108), Expect = 2e-04
Identities = 49/208 (23%), Positives = 86/208 (41%), Gaps = 18/208 (8%)
Query: 185 SVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDG-DLTD 243
S GSDS S N +S S+ D S + SS D D + S S+D D + +D
Sbjct: 847 SSDGSDSDSSNRSDSSNSS----DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD 902
Query: 244 TVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDP 303
+ S S +SD + S S+ S + N +++ +SSD++ +S + + + D
Sbjct: 903 SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962
Query: 304 PDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSL-GR 362
++ + S S + ++ + S DS N S S
Sbjct: 963 SNSSDSSD------------SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010
Query: 363 DSPDTMLASPQEEGEGPSSTTESSERSE 390
DS D+ +S S++++SS+ S+
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSD 1038
Score = 45.1 bits (105), Expect = 3e-04
Identities = 65/308 (21%), Positives = 117/308 (37%), Gaps = 17/308 (5%)
Query: 177 DFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDW 236
D D SS + S S +S +S S+N D S + SS D D + S S+D
Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSS-DSSNSSDSSNSSDSSDSSDSSDSSDSSDS 1048
Query: 237 EDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKE 296
D S S +SD + S S+ S + + + +E+ SSD++ +S +
Sbjct: 1049 SD-------SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Query: 297 EAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGD-GDSRN 355
+ + D D+ + + S ++S + + + D DS +
Sbjct: 1102 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Query: 356 GSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVID 415
S S DS D+ +S S +++SS+ S+ + D+S S D
Sbjct: 1162 SSDS--SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS----DSSDSSDSSDSSDSSDSSD 1215
Query: 416 QLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTV 475
+ S+ S + ++S + D+ + D S+ + ES S
Sbjct: 1216 --SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273
Query: 476 TSGGGHHD 483
SG G+++
Sbjct: 1274 KSGNGNNN 1281
Score = 44.7 bits (104), Expect = 5e-04
Identities = 41/210 (19%), Positives = 86/210 (40%), Gaps = 10/210 (4%)
Query: 185 SVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDT 244
S + SDS + +S S + DS+ + SS+ D D + S S+D D +
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSD-SDSSDSSNSSDSSDSSDSSDSSD 615
Query: 245 VSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPP 304
S + SD + S++ + + + + +++ +SD++ +S + + + D
Sbjct: 616 SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675
Query: 305 DACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPA----CSQKKCAKQGDGDSRNGSPSL 360
D+ + + + S ++S + S + D DS N S
Sbjct: 676 DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS--- 732
Query: 361 GRDSPDTMLASPQEEGEGPSSTTESSERSE 390
DS D+ +S + S++++SS+ S+
Sbjct: 733 --DSSDSSNSSDSSDSSDSSNSSDSSDSSD 760
Score = 44.3 bits (103), Expect = 6e-04
Identities = 46/209 (22%), Positives = 89/209 (42%), Gaps = 12/209 (5%)
Query: 189 SDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWED-GDLTDTVSG 247
SDS NS + S++ + DS+ + SS+ + D + S S+D D D +D+ S
Sbjct: 569 SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD---SSDSSDSSDSSDSSDSSDSKSD 625
Query: 248 PR-----STASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALD 302
S+ SD S + + S N + + + + +SSD++ +S + + +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 303 PPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGD-GDSRNGSPSLG 361
D+ + ++ S S + + + S + D DS N S S
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS-- 743
Query: 362 RDSPDTMLASPQEEGEGPSSTTESSERSE 390
DS D+ +S + S++++SS+ S+
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772
Score = 44.3 bits (103), Expect = 6e-04
Identities = 49/223 (21%), Positives = 88/223 (39%), Gaps = 17/223 (7%)
Query: 177 DFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDW 236
D D SS S S S NS +S S+ D S + SS+ D D S S+D
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSS----DSSNSSESSDSSDSSDS----DSSDSSDS 718
Query: 237 EDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKE 296
+ + +D+ S S +SD ++S S+ S + + + +++ +SSD++ +S +
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778
Query: 297 EAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNG 356
+ + D D+ + + S ++S + S DS N
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838
Query: 357 SPSLGR---------DSPDTMLASPQEEGEGPSSTTESSERSE 390
S S DS + +S + S ++ SS+ S+
Sbjct: 839 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSD 881
Score = 43.5 bits (101), Expect = 0.001
Identities = 47/207 (22%), Positives = 80/207 (38%), Gaps = 18/207 (8%)
Query: 185 SVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDT 244
S SDS S +S +S S + + D S + SS+ + D + S S+D D
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD------ 757
Query: 245 VSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPP 304
S S +SD + S S+ S + + + + + SSD++ +S + + + D
Sbjct: 758 -SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 305 DACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGR-D 363
D+ S ++S + + D DS N S S D
Sbjct: 817 DS----------DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 364 SPDTMLASPQEEGEGPSSTTESSERSE 390
S D+ +S + S + ESS S+
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSD 893
Score = 43.1 bits (100), Expect = 0.001
Identities = 48/221 (21%), Positives = 86/221 (38%), Gaps = 15/221 (6%)
Query: 177 DFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDW 236
D D SS S S ++ NS S+N D S + SS D + + S S+D
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSS-DSSDSSDSSNSSDSSNSSDSSNSSDSSDS 971
Query: 237 EDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKE 296
D +D+ S +SD + S S+ S + + + +++ SSD++ +S +
Sbjct: 972 NSSDSSDS-----SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026
Query: 297 EAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGD------ 350
+ + D D+ + + S ++S + + D
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSD 1086
Query: 351 -GDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSE 390
DS N S S DS D+ +S + S +++SS S+
Sbjct: 1087 SSDSSNSSDS--SDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1125
Score = 42.4 bits (98), Expect = 0.002
Identities = 47/208 (22%), Positives = 85/208 (40%), Gaps = 12/208 (5%)
Query: 185 SVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGD-LTD 243
S SDS S +S NS S+ DS+ + S D + S +D D D +D
Sbjct: 587 SSDSSDSDSSDSSNSSDSS-----DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641
Query: 244 TVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDP 303
+ S +SD + S S+ S + + + +++ SSSD++ +S + + + +
Sbjct: 642 SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSES 701
Query: 304 PDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGD-GDSRNGSPSLGR 362
D+ + + SD ++S + + D DS N S S
Sbjct: 702 SDSSDSSD---SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS--S 756
Query: 363 DSPDTMLASPQEEGEGPSSTTESSERSE 390
DS D+ +S + S +++SS S+
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Score = 42.0 bits (97), Expect = 0.003
Identities = 42/210 (20%), Positives = 82/210 (39%), Gaps = 2/210 (0%)
Query: 180 DRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDG 239
D SS S S NS S S++ DS+ + S + + D + S S
Sbjct: 682 DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741
Query: 240 DLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQ 299
D +D S S +SD + S S+ S + + + +++ +SSD+ +S + +
Sbjct: 742 DSSD--SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799
Query: 300 ALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPS 359
+ D ++ + + S S + + + + S DS + + S
Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRS 859
Query: 360 LGRDSPDTMLASPQEEGEGPSSTTESSERS 389
+S D+ +S S +++S+E S
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889
Score = 42.0 bits (97), Expect = 0.003
Identities = 49/224 (21%), Positives = 88/224 (39%), Gaps = 21/224 (9%)
Query: 185 SVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDG----- 239
S + SDS NS +S S+N D S + SS+ D D + S S+D D
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSS-DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 240 -----------DLTDTV-SGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTP 287
D +D+ S S +SD + S S+ S + + + +++ SSD++
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Query: 288 VHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAK 347
+S + + + D D+ + + S + ++S + +
Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140
Query: 348 QGD-GDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSE 390
D DS S S DS D+ +S + S +++SS S+
Sbjct: 1141 SSDSSDSSESSDS--SDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182
Score = 42.0 bits (97), Expect = 0.003
Identities = 46/217 (21%), Positives = 80/217 (36%), Gaps = 9/217 (4%)
Query: 177 DFEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDW 236
D D SS S S NS +S S++ D S + SS+ D D + S S+D
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSS-DSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 237 EDG-------DLTDTV-SGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPV 288
D D +D+ S S +SD + S S+ S + + +++ SSD++
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 289 HTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQ 348
+S + + + D D+ + + S ++S + +
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS 1252
Query: 349 GDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTES 385
D + S S D D+ S G S ++S
Sbjct: 1253 SDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDS 1289
Score = 41.2 bits (95), Expect = 0.005
Identities = 42/202 (20%), Positives = 82/202 (40%), Gaps = 11/202 (5%)
Query: 189 SDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLTDTVSGP 248
SD+ + +S + + N + D S D D + S S+D D D +D+ S
Sbjct: 519 SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578
Query: 249 RSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALDPPDACT 308
S +SD SS +S + N + + +++ SSD++ +S K ++ + + +
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSN--SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636
Query: 309 ELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTM 368
+ K S S + + + S DS + S S DS ++
Sbjct: 637 D-------SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS--SDSSNSS 687
Query: 369 LASPQEEGEGPSSTTESSERSE 390
+S + S +++SS+ S+
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSD 709
Score = 30.8 bits (68), Expect = 6.8
Identities = 37/186 (19%), Positives = 64/186 (34%), Gaps = 16/186 (8%)
Query: 217 EDYDFGDVFPAVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEP 276
+ YDF D S+D +G+ D S + +S + ++ N + +
Sbjct: 451 DSYDFDDKSMQGDDPNSSDESNGN-DDANSESDNNSSSRGDASYNSDESKDNGNGSDSKG 509
Query: 277 AETVSSSDTTPVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPL 336
AE S T+ + + D D K GK K SD ++S
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDDND------------KSDSGKGKSDSSDSDSSD- 556
Query: 337 HPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIP 396
+ + + D DS + + S DS D+ + + SS + S S
Sbjct: 557 --SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS 614
Query: 397 EMKDTS 402
+ D+S
Sbjct: 615 DSSDSS 620
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 47.8 bits (112), Expect = 5e-05
Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 20/179 (11%)
Query: 235 DWEDGDL----TDTVSGPRSTASDLTSSKASTRSPTQRQNP--FNEEPAETVSSSDTTPV 288
D +DGD D +S S++ + SKA ++P Q + P +E+ + S + P
Sbjct: 260 DSDDGDFEGQEVDYMSDGSSSSQEEPESKA--KAPQQEEGPKGVDEQSDSSEESEEEKPP 317
Query: 289 HTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQ 348
+E+EE +A P + KK++ ++S S EE+ A S AK+
Sbjct: 318 EEDKEEEEEKKAPTPQE-----------KKRRKDSSEESDSSEESDIDSEASSALFMAKK 366
Query: 349 GDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTE-SSERSEPGLLIPEMKDTSMERL 406
R PS G ++ +P EG SST ++ + E G + EM RL
Sbjct: 367 KTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRL 425
>gi|221307580 RUN domain containing 3A isoform 3 [Homo sapiens]
Length = 400
Score = 46.6 bits (109), Expect = 1e-04
Identities = 42/179 (23%), Positives = 73/179 (40%), Gaps = 15/179 (8%)
Query: 17 SVKKLQSYFAA--CEDEIPAIRNHDKVLQRLCEH-LDHALLYGLQDLSSGYWV---LVVH 70
SVK L + A +D N +L+++ H + + D G+W L
Sbjct: 38 SVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKGPVSWFSSDGQRGFWDYIRLACS 97
Query: 71 FTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALV 130
+ IE +++++T + RAW+ +AL E + Y+ + ++Y A++
Sbjct: 98 KVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIM 157
Query: 131 CSHDHLTLFLTLVSGLEFIRFE-------LDLDAP-YLDLAPYMPDYYKPQYLLDFEDR 181
D T+ ++ GL I F LD P +D PY+ YL D E+R
Sbjct: 158 L-RDEATILTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEER 215
>gi|197304746 RUN domain containing 3B isoform c [Homo sapiens]
Length = 407
Score = 46.6 bits (109), Expect = 1e-04
Identities = 45/196 (22%), Positives = 82/196 (41%), Gaps = 8/196 (4%)
Query: 17 SVKKL--QSYFAACEDEIPAIRNHDKVLQRLCEH-LDHALLYGLQDLSSGYWVLVVHFTR 73
SVK L +S F +D P N +L+++ H L + + + +W + R
Sbjct: 43 SVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACR 102
Query: 74 R---EAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALV 130
+ I IE +++V+++ + RAW+ +AL E L Y+ + ++Y A+V
Sbjct: 103 KVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIV 162
Query: 131 CSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLA-PYMPDYYKPQYLLDFEDRLPSSVHGS 189
+ + ++ GL I F L LD + P + DY + D + S
Sbjct: 163 LG-EEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEEL 221
Query: 190 DSLSLNSFNSVTSTNL 205
+L + S T N+
Sbjct: 222 RTLGSSGSESSTPENV 237
>gi|197304744 RUN domain containing 3B isoform b [Homo sapiens]
Length = 456
Score = 46.6 bits (109), Expect = 1e-04
Identities = 45/196 (22%), Positives = 82/196 (41%), Gaps = 8/196 (4%)
Query: 17 SVKKL--QSYFAACEDEIPAIRNHDKVLQRLCEH-LDHALLYGLQDLSSGYWVLVVHFTR 73
SVK L +S F +D P N +L+++ H L + + + +W + R
Sbjct: 43 SVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKGQVTWFGYESPRSFWDYIRVACR 102
Query: 74 R---EAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALV 130
+ I IE +++V+++ + RAW+ +AL E L Y+ + ++Y A+V
Sbjct: 103 KVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIV 162
Query: 131 CSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLA-PYMPDYYKPQYLLDFEDRLPSSVHGS 189
+ + ++ GL I F L LD + P + DY + D + S
Sbjct: 163 LG-EEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEEL 221
Query: 190 DSLSLNSFNSVTSTNL 205
+L + S T N+
Sbjct: 222 RTLGSSGSESSTPENV 237
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 45.4 bits (106), Expect = 3e-04
Identities = 88/460 (19%), Positives = 149/460 (32%), Gaps = 59/460 (12%)
Query: 186 VHGSDSLSLNSFNSVTSTNLEWDDSAIA--PSSEDYDFGDVFPAVPSVPSTDWEDGDLTD 243
VH S + + ST + + + P+S+D P+ P+T +L+
Sbjct: 4446 VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD--------TTPAPPTTTSAFVELST 4497
Query: 244 TVSG-PRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALD 302
T G P ST + S+ ++T ++ + P T ++ TTS EE+
Sbjct: 4498 TSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPAR-STTSGLVEESTTYH 4556
Query: 303 PPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPSLGR 362
T+ + + + + + +S H S + + S G
Sbjct: 4557 SSPGSTQ--TMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 4614
Query: 363 DSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLD 422
+ S G ST S + G ++ + T+ LG+ + I +G ++
Sbjct: 4615 TATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPIS--SGSME 4672
Query: 423 PSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGL-------------SAPMDFYRFTV 469
+ P S ++ + +P P FS S+P+ T
Sbjct: 4673 TTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA--TATT 4730
Query: 470 ESPSTVTSGG------GHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTRE 523
SP+ T+ G +H G Q +H P S A+G+ EE T +
Sbjct: 4731 PSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST 4790
Query: 524 AQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHS 583
+LV E PG S + +S G+ S HS
Sbjct: 4791 TS------ALVEEPTSYHSSPG-------------SIATTHFPESSTTSGRSEESTASHS 4831
Query: 584 SEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNL 623
S D N + L H +S G ME L
Sbjct: 4832 SP---DTNGITPLPAHFTTSGRIAESTTFYISPGSMETTL 4868
Score = 40.8 bits (94), Expect = 0.007
Identities = 83/362 (22%), Positives = 120/362 (33%), Gaps = 48/362 (13%)
Query: 178 FEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIA-----PSSEDYDFGDV-FPAVPSV 231
F D +S H +S +S T T L SA + P + + A+P
Sbjct: 211 FLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGS 270
Query: 232 PSTDWEDGDLTDTVSGPRSTASDL-----TSSKASTRSPTQRQNPFNEEPAETVSSSDTT 286
+T T S PRS L TSS S +S T P P T++ D+T
Sbjct: 271 TTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRP---GPTHTIAFPDST 327
Query: 287 PVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCA 346
+ SQE + ++ P T L G S E++ H + K
Sbjct: 328 TMPGVSQESTASHSI-PGSTDTTLSP---------GTTTPSSLGPESTTFHSSPGYTKTT 377
Query: 347 KQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERL 406
+ D + +G L +P PSS+T P KDTS
Sbjct: 378 RLPDNTTTSGL--LEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPS 435
Query: 407 GQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSP--GDAPERPPLCDFSEGLSAPMDF 464
G + V +L + S + P F S G + E P+ S+P+
Sbjct: 436 GTTSAFV------KLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVH------SSPVA- 482
Query: 465 YRFTVESPSTVTSGG------GHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLE 518
T P+ + G +H G Q +H P S +G EE G T
Sbjct: 483 -TATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS 541
Query: 519 DT 520
T
Sbjct: 542 ST 543
Score = 37.4 bits (85), Expect = 0.073
Identities = 93/420 (22%), Positives = 136/420 (32%), Gaps = 53/420 (12%)
Query: 183 PSSVHGSD-SLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVP------STD 235
P+S H S S + F ++T+ ++S + SS+D V PA + +T
Sbjct: 3522 PTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 3581
Query: 236 WEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEK 295
+T + P ST + S K++T + R PA T SS + T+
Sbjct: 3582 PISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRP 3641
Query: 296 EEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRN 355
PD+ T + R + + AS SQ+ S +
Sbjct: 3642 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTD 3701
Query: 356 GSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVID 415
+ S G T L+ QE S+T SS S L P+ +S
Sbjct: 3702 TALSPG---STTALSFGQE-----STTFHSSPGSTHTTLFPDSTTSS------------- 3740
Query: 416 QLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTV 475
G ++ ST R S RT + P L S T PST
Sbjct: 3741 ---GIVEAST---RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 3794
Query: 476 TS----GGGHHDPAGLGQPLHVPSSPEAAGQEEE------GGGGEGQTPRPLEDTTREAQ 525
T+ +H G H P+S +G E+ G TP TT +
Sbjct: 3795 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT--SG 3852
Query: 526 ELEAQLSLVREG-------PVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPS 578
E+ S + G P S PG E SP + + S G G S
Sbjct: 3853 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 3912
Score = 35.8 bits (81), Expect = 0.21
Identities = 93/420 (22%), Positives = 136/420 (32%), Gaps = 53/420 (12%)
Query: 183 PSSVHGSD-SLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVP------STD 235
P+S H S S + F ++T+ ++S + SS+D V PA + +T
Sbjct: 1965 PTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 2024
Query: 236 WEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEK 295
+T + P ST + S K++T + R PA T SS + T+
Sbjct: 2025 PISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRP 2084
Query: 296 EEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRN 355
PD+ T + R + + AS SQ+ S +
Sbjct: 2085 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD 2144
Query: 356 GSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVID 415
+ S G T L+ QE S+T SS S L P+ +S
Sbjct: 2145 TALSPG---STTALSFGQE-----STTFHSSPGSTHTTLFPDSTTSS------------- 2183
Query: 416 QLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTV 475
G ++ ST R S RT + P L S T PST
Sbjct: 2184 ---GIVEAST---RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 2237
Query: 476 TS----GGGHHDPAGLGQPLHVPSSPEAAGQEEE------GGGGEGQTPRPLEDTTREAQ 525
T+ +H G H P+S +G E+ G TP TT +
Sbjct: 2238 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT--SG 2295
Query: 526 ELEAQLSLVREG-------PVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPS 578
E+ S + G P S PG E SP + + S G G S
Sbjct: 2296 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 2355
Score = 34.7 bits (78), Expect = 0.47
Identities = 70/316 (22%), Positives = 105/316 (33%), Gaps = 31/316 (9%)
Query: 227 AVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEP--AETVSSSD 284
A P +T T + S P ST + L + +T P+Q + P +T S
Sbjct: 2091 AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPG 2150
Query: 285 TTPVHTTSQEKEEAQALDP-------PDACTELEVIRVTKKKKIGKKKKSRSDEEASPLH 337
+T + QE + PD+ T ++ + + + AS
Sbjct: 2151 STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS 2210
Query: 338 PACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPE 397
P + A Q S + +P SP + +P EE S+T S S P P
Sbjct: 2211 PGLQGESTAFQTHPASTHTTP-----SPPSTATAPVEE----STTYHRSPGSTPTTHFPA 2261
Query: 398 MKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAP-ERPPLCDFSE 456
TS + +G S + + + + SPG P +
Sbjct: 2262 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP 2321
Query: 457 GLS-APMDFYR-----FTVESPSTVTS-GGGHHDPAGLGQPLHV-----PSSPEAAGQEE 504
GLS A FY T SP+++TS G G QP P+S G E
Sbjct: 2322 GLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 2381
Query: 505 EGGGGEGQTPRPLEDT 520
E +P E T
Sbjct: 2382 ESTTVYSSSPGSTETT 2397
Score = 34.3 bits (77), Expect = 0.61
Identities = 91/420 (21%), Positives = 136/420 (32%), Gaps = 53/420 (12%)
Query: 183 PSSVHGSD-SLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVP------STD 235
P+S H S S + F ++T+ ++S + SS+D V PA + +T
Sbjct: 882 PTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS 941
Query: 236 WEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEK 295
+T + P ST + S +++T + R PA T SS + T+
Sbjct: 942 PISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRP 1001
Query: 296 EEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRN 355
PD+ T + R + + AS SQ+ S +
Sbjct: 1002 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTD 1061
Query: 356 GSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLSKVID 415
+ S G T L+ QE S+T S+ S L P+ +S
Sbjct: 1062 TALSPG---STTALSFGQE-----STTFHSNPGSTHTTLFPDSTTSS------------- 1100
Query: 416 QLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTV 475
G ++ ST R S RT + P L S T PST
Sbjct: 1101 ---GIVEAST---RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 1154
Query: 476 TS----GGGHHDPAGLGQPLHVPSSPEAAGQEEE------GGGGEGQTPRPLEDTTREAQ 525
T+ +H G H P+S +G E+ G TP TT +
Sbjct: 1155 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT--SG 1212
Query: 526 ELEAQLSLVREG-------PVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPS 578
E+ S + G P S PG E SP + + S G G S
Sbjct: 1213 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES 1272
Score = 33.1 bits (74), Expect = 1.4
Identities = 95/437 (21%), Positives = 144/437 (32%), Gaps = 79/437 (18%)
Query: 184 SSVHGSDSLSLNSFNSVTSTNL-EWDDSAIAPSSEDYDFGDVFPAVPSV------PSTDW 236
++ H S + + S +ST L ++S SS +FP + P+T
Sbjct: 1608 TTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSP 1667
Query: 237 EDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKE 296
T+T + P ST + S K++T + R PA T SS + T+
Sbjct: 1668 ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 1727
Query: 297 EAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNG 356
P + T + V+++ +D SP S
Sbjct: 1728 STHTTAFPGSTT---MPGVSQESTASHSSPGSTDTTLSPGSTTAS--------------- 1769
Query: 357 SPSLGRDSPDTMLASP--QEEGEGPSSTTESS--ERSEPGLLIPEMKDTSMERLGQPLSK 412
SLG +S T +SP E P +TT S E S P T++ G ++
Sbjct: 1770 --SLGPEST-TFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGST-TR 1825
Query: 413 VIDQLNGQLDPSTWCSRAEPPDQS-----FRTGSPGDAPERPPLCDFSEGL--------- 458
+ Q PS+ + PP + T S G +P P FS
Sbjct: 1826 QGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHG-SPSSTPTTHFSASSTTLGRSEES 1884
Query: 459 ----SAPMDFYRFTVESPSTVTSGG------GHHDPAGLGQPLHVPSSPEAAGQEEEGGG 508
S+P+ T SP+ T+ G +H G Q +H P S A+G+ EE
Sbjct: 1885 TTVHSSPVA--TATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1942
Query: 509 GEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDS 568
T + +LV E PG S + DS
Sbjct: 1943 SHSSTTHTISSPPSTTS------ALVEEPTSYHSSPG-------------STATTHFPDS 1983
Query: 569 GVDEGQGSPSEMVHSSE 585
G+ S HSS+
Sbjct: 1984 STTSGRSEESTASHSSQ 2000
Score = 33.1 bits (74), Expect = 1.4
Identities = 69/316 (21%), Positives = 104/316 (32%), Gaps = 31/316 (9%)
Query: 227 AVPSVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEP--AETVSSSD 284
A P +T T + S P ST + L + +T P+Q + P +T S
Sbjct: 2565 AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPG 2624
Query: 285 TTPVHTTSQEKEEAQALDP-------PDACTELEVIRVTKKKKIGKKKKSRSDEEASPLH 337
+T + QE + PD+ T ++ + + + AS
Sbjct: 2625 STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS 2684
Query: 338 PACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPE 397
P + Q S + +P SP + +P EE S+T S S P P
Sbjct: 2685 PGLQGESTTFQTHPASTHTTP-----SPPSTATAPVEE----STTYHRSPGSTPTTHFPA 2735
Query: 398 MKDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAP-ERPPLCDFSE 456
TS + +G S + + + + SPG P +
Sbjct: 2736 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP 2795
Query: 457 GLS-APMDFYR-----FTVESPSTVTS-GGGHHDPAGLGQPLHV-----PSSPEAAGQEE 504
GLS A FY T SP+++TS G G QP P+S G E
Sbjct: 2796 GLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 2855
Query: 505 EGGGGEGQTPRPLEDT 520
E +P E T
Sbjct: 2856 ESTTVYSSSPGSTETT 2871
Score = 30.4 bits (67), Expect = 8.9
Identities = 29/119 (24%), Positives = 50/119 (42%), Gaps = 9/119 (7%)
Query: 178 FEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPA-----VPSVP 232
F +SVHG + + +S + T T L +DS + +E+ PA +P+
Sbjct: 1316 FPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 1375
Query: 233 STDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAE----TVSSSDTTP 287
+T + T S ST + L+ ++++T P P+ T+ S TTP
Sbjct: 1376 TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTP 1434
>gi|221307578 RUN domain containing 3A isoform 1 [Homo sapiens]
Length = 446
Score = 45.4 bits (106), Expect = 3e-04
Identities = 43/184 (23%), Positives = 74/184 (40%), Gaps = 20/184 (10%)
Query: 17 SVKKLQSYFAA--CEDEIPAIRNHDKVLQRLCEHLDHA------LLYGLQDLSSGYWV-- 66
SVK L + A +D N +L+++ H A + + D G+W
Sbjct: 38 SVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYI 97
Query: 67 -LVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYV 125
L + IE +++++T + RAW+ +AL E + Y+ + ++Y
Sbjct: 98 RLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYD 157
Query: 126 KNALVCSHDHLTLFLTLVSGLEFIRFE-------LDLDAP-YLDLAPYMPDYYKPQYLLD 177
A++ D T+ ++ GL I F LD P +D PY+ YL D
Sbjct: 158 SGAIML-RDEATILTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTD 216
Query: 178 FEDR 181
E+R
Sbjct: 217 EEER 220
>gi|5730015 RUN domain containing 3A isoform 2 [Homo sapiens]
Length = 405
Score = 45.4 bits (106), Expect = 3e-04
Identities = 43/184 (23%), Positives = 74/184 (40%), Gaps = 20/184 (10%)
Query: 17 SVKKLQSYFAA--CEDEIPAIRNHDKVLQRLCEHLDHA------LLYGLQDLSSGYWV-- 66
SVK L + A +D N +L+++ H A + + D G+W
Sbjct: 38 SVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYI 97
Query: 67 -LVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYV 125
L + IE +++++T + RAW+ +AL E + Y+ + ++Y
Sbjct: 98 RLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYD 157
Query: 126 KNALVCSHDHLTLFLTLVSGLEFIRFE-------LDLDAP-YLDLAPYMPDYYKPQYLLD 177
A++ D T+ ++ GL I F LD P +D PY+ YL D
Sbjct: 158 SGAIML-RDEATILTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTD 216
Query: 178 FEDR 181
E+R
Sbjct: 217 EEER 220
>gi|239747798 PREDICTED: hypothetical protein XP_002348316 [Homo
sapiens]
Length = 399
Score = 45.1 bits (105), Expect = 3e-04
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 8/171 (4%)
Query: 230 SVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVH 289
S+ +T+ +DG+ + TVS + A TS + + S R+ + E + TV+S +
Sbjct: 231 SIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKK-DGEISRTVTSEKPAGLK 289
Query: 290 TTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQG 349
TS E++ + E + RV+ +KK K+ SDE+ S +KK +
Sbjct: 290 ATSDEEDSVLNIARGKEDGE-KTRRVSSRKK--PALKATSDEKDS-FSNITREKKDGETS 345
Query: 350 DGDSRNGSPSLGR--DSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEM 398
S P+L D D++L+ +EE +G S T SSE+ PGL + ++
Sbjct: 346 RTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQ-PPGLKVMKL 395
Score = 41.6 bits (96), Expect = 0.004
Identities = 56/203 (27%), Positives = 92/203 (45%), Gaps = 16/203 (7%)
Query: 233 STDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTS 292
+T+ +DG+ ++TVS + A T+ + + S + + E + TVSS + TS
Sbjct: 200 ATEIKDGEKSETVSSQKQPALKATTDEEDSVSIIATEIK-DGEKSGTVSSRKKPALKATS 258
Query: 293 QEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGD 352
EK+ + E+ VT +K G K+ SDEE S L+ A ++ K
Sbjct: 259 DEKDSFSNITREKKDGEIS-RTVTSEKPAG--LKATSDEEDSVLNIARGKEDGEKTRRVS 315
Query: 353 SRNGSPSL--GRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPL 410
SR P+L D D+ +E+ +G +S T SS++ P +K TS E L
Sbjct: 316 SRK-KPALKATSDEKDSFSNITREKKDGETSRTVSSQKP------PALKATSDEE-DSVL 367
Query: 411 SKVIDQLNGQLDPSTWCSRAEPP 433
S ++ +G + S S +PP
Sbjct: 368 SIAREEKDG--EKSRTVSSEQPP 388
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 44.3 bits (103), Expect = 6e-04
Identities = 46/219 (21%), Positives = 89/219 (40%), Gaps = 27/219 (12%)
Query: 259 KASTRSPTQRQNPFNEE---PAETVSSSDTTPVHTTSQEK-EEAQALDPPDACTELEVIR 314
K +SP + ++P E+ P + + + +EK +E + +PP E +
Sbjct: 790 KEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA 849
Query: 315 V--TKKKKIGKKKKSRSDEEASPL-----HPACSQKKC----AKQGDGDSRNGSPSLGRD 363
T++KK KK+++ E P PA + K AK+ + + + P+ ++
Sbjct: 850 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE 909
Query: 364 SPDTML----ASPQEEGEGPSSTTESSERSEPGL------LIPEMKDTSMERLGQPLSKV 413
+P + A P+E+ E + ++ EP PE KDT E+ +P K
Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP 969
Query: 414 IDQLNGQLDPSTWCSRAEPP--DQSFRTGSPGDAPERPP 450
+ + D T P +++ ++ S +PP
Sbjct: 970 KTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPP 1008
Score = 30.4 bits (67), Expect = 8.9
Identities = 18/71 (25%), Positives = 30/71 (42%), Gaps = 1/71 (1%)
Query: 498 EAAGQEEEGGGGEGQTPR-PLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRD 556
E G+EEE GGE +T P E+ +E ++ + + P P +E +
Sbjct: 486 EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545
Query: 557 QPSPCLSSAED 567
P S A++
Sbjct: 546 SPEKAKSPAKE 556
>gi|21328446 hormone-sensitive lipase [Homo sapiens]
Length = 1076
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/180 (23%), Positives = 69/180 (38%), Gaps = 15/180 (8%)
Query: 226 PAVPSVPSTDWE----DGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFN-------E 274
P SV +DW+ +T GP T SK S TQ++ N E
Sbjct: 3 PGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQE 62
Query: 275 EPAETVSSSDTTP---VHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDE 331
PA+ + S P + SQE+ A P ++ + +T+++ ++ E
Sbjct: 63 TPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKE 122
Query: 332 EASPLHPACSQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEP 391
+ PA Q+ A+ G G +S A P + E PS+ TES+ + P
Sbjct: 123 SITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKRE-PSAPTESTSQETP 181
>gi|7662352 RUN and FYVE domain containing 3 isoform 2 [Homo
sapiens]
Length = 469
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 8/101 (7%)
Query: 75 EAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHD 134
E ++ L + T +GR RAWL LAL + L Y++ LL ++Y NAL+ +
Sbjct: 145 EITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEE 204
Query: 135 HLTLFLTLVSGLEFIRF-------ELDLDAPYLDLAPYMPD 168
+ L+ GL I +LD +D + Y+ D
Sbjct: 205 G-AIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKD 244
>gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 620
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 8/101 (7%)
Query: 75 EAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHD 134
E ++ L + T +GR RAWL LAL + L Y++ LL ++Y NAL+ +
Sbjct: 145 EITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEE 204
Query: 135 HLTLFLTLVSGLEFIRF-------ELDLDAPYLDLAPYMPD 168
+ L+ GL I +LD +D + Y+ D
Sbjct: 205 G-AIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKD 244
>gi|195220720 RUN and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/101 (28%), Positives = 46/101 (45%), Gaps = 8/101 (7%)
Query: 75 EAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHD 134
E ++ L + T +GR RAWL LAL + L Y++ LL ++Y NAL+ +
Sbjct: 205 EITASVKDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEE 264
Query: 135 HLTLFLTLVSGLEFIRF-------ELDLDAPYLDLAPYMPD 168
+ L+ GL I +LD +D + Y+ D
Sbjct: 265 G-AIIAGLLVGLNVIDANFCMKGEDLDSQVGVIDFSMYLKD 304
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 42.4 bits (98), Expect = 0.002
Identities = 95/424 (22%), Positives = 145/424 (34%), Gaps = 85/424 (20%)
Query: 183 PSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEDGDLT 242
PSS+ S + S NS + NL+ + SE + D+ P+
Sbjct: 1570 PSSLESSRNTSSNS----SPLNLKGSSEQLHGRSESFSSEDLIPS--------------R 1611
Query: 243 DTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQALD 302
D + PR ++ ++ P R P +E A+ T P + +
Sbjct: 1612 DLATLPREASTPGRNALGRHEYPLPRNGPLPQEGAQ---KRGTAPPYV---------GVR 1659
Query: 303 PPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLH--PACSQKKCA----KQGDGDSRNG 356
P A E+ VT ++ + + +S SP H P+C + K D + G
Sbjct: 1660 PCSASPSSEM--VTLEEFLEESNRS------SPTHDTPSCRDDLLSDYFRKASDPPAIGG 1711
Query: 357 SPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERLGQPLS----- 411
P P + EG T + P +K + G+PL
Sbjct: 1712 QPG------------PPAKKEGAKMPTN--------FVAPTVKMAAPTSEGRPLKPGQYV 1751
Query: 412 KVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVES 471
K +L P + R P QS G P AP PP SA + F++ S
Sbjct: 1752 KPNFRLTEAEAPPSVAPRQAQPPQSLSLGRPRQAPV-PPASHAPASRSASLS-RAFSLAS 1809
Query: 472 PSTVTSGGGHHDPAGLGQPLHVPSSPEAAGQEEEGGGG-EGQTPRPLEDTTREAQEL--E 528
+ + G Q L +PEA G E G + P RE L +
Sbjct: 1810 ADLLRASGPEACKQESPQKL---GAPEALGGRETGSHTLQSPAPPSSHSLARERTPLVGK 1866
Query: 529 AQLSLVREGPVSEP--------EPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEM 580
A S GP S P P +E L L + +P +++A G GS S++
Sbjct: 1867 AGSSCQGPGPRSRPLDTRRFSLAPPKEERLAPLHQSATAPAIATAGAGAAAAGSGSNSQL 1926
Query: 581 VHSS 584
+H S
Sbjct: 1927 LHFS 1930
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 42.0 bits (97), Expect = 0.003
Identities = 35/180 (19%), Positives = 75/180 (41%), Gaps = 10/180 (5%)
Query: 230 SVPSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVH 289
S+ +T+ +DG+ + TVS + A TS + + S R+ + E + TVSS +
Sbjct: 487 SIIATEIKDGEKSGTVSSRKKPALKATSDEKDSFSNITREKK-DGEISRTVSSQKPPALK 545
Query: 290 TTSQEKEEAQALDPPD---------ACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPAC 340
TS E++ ++ + + + ++ T+ +K +R +
Sbjct: 546 ATSDEEDSVLSIAREEKDGEKSRTVSSEQPPGLKATRDEKDSLLNIARGKKYGEKTRRVS 605
Query: 341 SQKKCAKQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKD 400
S K+ A + D N P++ ++ D ++ + P+ S ++ + E+KD
Sbjct: 606 SHKQPALKATSDKENSVPNMATETKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEIKD 665
Score = 37.0 bits (84), Expect = 0.095
Identities = 47/167 (28%), Positives = 73/167 (43%), Gaps = 16/167 (9%)
Query: 233 STDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNE----EPAETVSSSDTTPV 288
+T+ +DG+ + TVS + A KA+T N E E +ETVSS +
Sbjct: 422 ATEIKDGEKSGTVSSQKQPAL-----KATTDEEDSVLNIATEIKDGEKSETVSSQKQPAL 476
Query: 289 HTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQ 348
T+ E++ + E ++KK K+ SDE+ S +KK +
Sbjct: 477 KATTDEEDSVSIIATEIKDGEKSGTVSSRKKPA---LKATSDEKDS-FSNITREKKDGEI 532
Query: 349 GDGDSRNGSPSLGR--DSPDTMLASPQEEGEGPSSTTESSERSEPGL 393
S P+L D D++L+ +EE +G S T SSE+ PGL
Sbjct: 533 SRTVSSQKPPALKATSDEEDSVLSIAREEKDGEKSRTVSSEQ-PPGL 578
>gi|66932943 variable charge, X chromosome [Homo sapiens]
Length = 206
Score = 41.6 bits (96), Expect = 0.004
Identities = 57/223 (25%), Positives = 87/223 (39%), Gaps = 37/223 (16%)
Query: 371 SPQEEGEGP-SSTTESSER---SEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTW 426
SP+ GP + TE+ +R S+P P+ K T + + G+ + + G+ +T
Sbjct: 2 SPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRR---GRRGKKGAATK 58
Query: 427 CSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAG 486
+ P+ +PG S+ S + + E P S G HDP
Sbjct: 59 MAAVTAPEAESAPAAPGP----------SDQPSQELPQHELPPEEP---VSEGTQHDPLS 105
Query: 487 LGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEP---- 542
L P S E+ + EE E Q PL +QE E + L +E V EP
Sbjct: 106 QEAELEEPLSQES--EVEEPLSQESQVEEPL------SQESEVEEPLSQESQVEEPLSQE 157
Query: 543 ----EPGTQEVLCQLKRDQPSPCLSS-AEDSGVDEGQGSPSEM 580
EP +QE + Q S +++S V+E SEM
Sbjct: 158 SEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPPSQESEM 200
>gi|19923090 RUN domain containing 3B isoform a [Homo sapiens]
Length = 473
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 27/214 (12%)
Query: 17 SVKKL--QSYFAACEDEIPAIRNHDKVLQRLCEH-----------LDHALL--------Y 55
SVK L +S F +D P N +L+++ H L H + +
Sbjct: 43 SVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWF 102
Query: 56 GLQDLSSGYWVLVVHFTRR---EAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRL 112
G + S +W + R+ I IE +++V+++ + RAW+ +AL E L Y+
Sbjct: 103 GYESPRS-FWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYIST 161
Query: 113 FQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLA-PYMPDYYK 171
+ ++Y A+V + + ++ GL I F L LD + P + DY
Sbjct: 162 ALRDFKTTRRFYEDGAIVLG-EEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTP 220
Query: 172 PQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNL 205
+ D + S +L + S T N+
Sbjct: 221 YLKYIQSSDSISSDEEELRTLGSSGSESSTPENV 254
>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
Length = 861
Score = 40.8 bits (94), Expect = 0.007
Identities = 83/362 (22%), Positives = 120/362 (33%), Gaps = 48/362 (13%)
Query: 178 FEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIA-----PSSEDYDFGDV-FPAVPSV 231
F D +S H +S +S T T L SA + P + + A+P
Sbjct: 67 FLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGS 126
Query: 232 PSTDWEDGDLTDTVSGPRSTASDL-----TSSKASTRSPTQRQNPFNEEPAETVSSSDTT 286
+T T S PRS L TSS S +S T P P T++ D+T
Sbjct: 127 TTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRP---GPTHTIAFPDST 183
Query: 287 PVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCA 346
+ SQE + ++ P T L G S E++ H + K
Sbjct: 184 TMPGVSQESTASHSI-PGSTDTTLSP---------GTTTPSSLGPESTTFHSSPGYTKTT 233
Query: 347 KQGDGDSRNGSPSLGRDSPDTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMERL 406
+ D + +G L +P PSS+T P KDTS
Sbjct: 234 RLPDNTTTSGL--LEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPS 291
Query: 407 GQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSP--GDAPERPPLCDFSEGLSAPMDF 464
G + V +L + S + P F S G + E P+ S+P+
Sbjct: 292 GTTSAFV------KLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVH------SSPVA- 338
Query: 465 YRFTVESPSTVTSGG------GHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLE 518
T P+ + G +H G Q +H P S +G EE G T
Sbjct: 339 -TATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKS 397
Query: 519 DT 520
T
Sbjct: 398 ST 399
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 40.8 bits (94), Expect = 0.007
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 83 LQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTL 142
L + T LGR+RAWL LAL + + YLR LL ++Y +AL+ + + + L
Sbjct: 130 LPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEYHALMMEEEG-AVIVGL 188
Query: 143 VSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFED 180
+ GL I L + LD + D+ YL + ED
Sbjct: 189 LVGLNVIDANLCVKGEDLDSQVGVIDF--SMYLKNEED 224
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 40.4 bits (93), Expect = 0.009
Identities = 86/363 (23%), Positives = 124/363 (34%), Gaps = 50/363 (13%)
Query: 178 FEDRLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIA-----PSSEDYDFGDV-FPAVPSV 231
F D +S H +S +S T T L SA + P + + A+P
Sbjct: 132 FLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGS 191
Query: 232 PSTDWEDGDLTDTVSGPRSTASDL-----TSSKASTRSPTQRQNPFNEEPAETVSSSDTT 286
+T T S PRS L TSS S +S T P P T++ D+T
Sbjct: 192 TTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRP---GPTHTIAFPDST 248
Query: 287 PVHTTSQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCA 346
+ SQE + ++ P T L G S E++ H + K
Sbjct: 249 TMPGVSQESTASHSI-PGSTDTTLSP---------GTTTPSSLGPESTTFHSSPGYTKTT 298
Query: 347 KQGDGDSRNGSPSLGRDSP-DTMLASPQEEGEGPSSTTESSERSEPGLLIPEMKDTSMER 405
+ D + +G L +P + SP SSTT E + P KDTS
Sbjct: 299 RLPDNTTTSGL--LEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSW-PSSKDTSPAP 355
Query: 406 LGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSP--GDAPERPPLCDFSEGLSAPMD 463
G + V +L + S + P F S G + E P+ S+P+
Sbjct: 356 SGTTSAFV------KLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVH------SSPVA 403
Query: 464 FYRFTVESPSTVTSGG------GHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQTPRPL 517
T P+ + G +H G Q +H P S +G EE G T
Sbjct: 404 --TATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTK 461
Query: 518 EDT 520
T
Sbjct: 462 SST 464
Score = 33.9 bits (76), Expect = 0.80
Identities = 85/411 (20%), Positives = 124/411 (30%), Gaps = 57/411 (13%)
Query: 232 PSTDWEDGDLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTT 291
P+T T+T + P ST + S K++T + R PA T SS + T+
Sbjct: 970 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 1029
Query: 292 SQEKEEAQALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACS----QKKCAK 347
P + T + V+++ +D SP S +
Sbjct: 1030 HSRPGSTHTTAFPGSTT---MPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFH 1086
Query: 348 QGDG--------DSRNGSPSLGRDSP-DTMLASPQEEGEGPSSTTESSERSEPGLLIPEM 398
G G D+ S L +P + SP+ STT E S P
Sbjct: 1087 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGE-STTFQSWPSS 1145
Query: 399 KDTSMERLGQPLSKVIDQLNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGL 458
KDT P +L ++ S + P F S S +
Sbjct: 1146 KDT------MPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPV 1199
Query: 459 SAPMDFYRFTVESPSTVTSGG------GHHDPAGLGQPLHVPSSPEAAGQEEEGGGGEGQ 512
+ T SP+ T+ G +H G Q +H P S A+G+ EE
Sbjct: 1200 APA------TTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSS 1253
Query: 513 TPRPLEDTTREAQELEAQLSLVREGPVSEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDE 572
T + +LV E PG S + +S
Sbjct: 1254 TTHTISSPPSTTS------ALVEEPTSYHSSPG-------------SIATTHFPESSTTS 1294
Query: 573 GQGSPSEMVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNL 623
G+ S HSS D N + L H +S G ME L
Sbjct: 1295 GRSEESTASHSSP---DTNGITPLPAHFTTSGRIAESTTFYISPGSMETTL 1342
>gi|48762947 variable charge, X-linked 3A [Homo sapiens]
Length = 186
Score = 40.0 bits (92), Expect = 0.011
Identities = 54/214 (25%), Positives = 84/214 (39%), Gaps = 39/214 (18%)
Query: 371 SPQEEGEGP-SSTTESSER---SEPGLLIPEMKDTSMERLGQPLSKVIDQLNGQLDPSTW 426
SP+ GP + TE+ +R S+P P+ K T + + G+ + + G+ +T
Sbjct: 2 SPKPRASGPPAKATEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRR---GRRGKKGAATK 58
Query: 427 CSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVTSGGGHHDPAG 486
+ P+ +PG S+ S + + E P S G HDP
Sbjct: 59 MAAVTAPEAESGPAAPGP----------SDQPSQELPQHELPPEEP---VSEGTQHDPLS 105
Query: 487 LGQPLHVPSSPEAAGQEEEGGGGEGQTPRPLEDTTREAQELEAQLSLVREGPVSEPEPGT 546
L P S E+ + EE E Q PL +QE E + L +E V EP
Sbjct: 106 QESELEEPLSQES--EVEEPLSQESQVEEPL------SQESEVEEPLSQESQVEEPLSQE 157
Query: 547 QEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEM 580
EV ++P +++S V+E SEM
Sbjct: 158 SEV------EEP-----LSQESQVEEPLSQESEM 180
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,061,024
Number of Sequences: 37866
Number of extensions: 2326449
Number of successful extensions: 8659
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 326
Number of HSP's that attempted gapping in prelim test: 7773
Number of HSP's gapped (non-prelim): 1107
length of query: 1019
length of database: 18,247,518
effective HSP length: 112
effective length of query: 907
effective length of database: 14,006,526
effective search space: 12703919082
effective search space used: 12703919082
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.