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Search of human proteins with 221139693
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221139693 hypothetical protein LOC199870 isoform 5 [Homo
sapiens]
(227 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221139693 hypothetical protein LOC199870 isoform 5 [Homo sapi... 460 e-130
gi|219881540 hypothetical protein LOC199870 isoform 4 [Homo sapi... 436 e-123
gi|22749341 hypothetical protein LOC199870 isoform 3 [Homo sapiens] 421 e-118
gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo sapi... 417 e-117
gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo sapi... 402 e-112
gi|134288896 hypothetical protein LOC143684 [Homo sapiens] 284 5e-77
gi|15208660 tripartite motif protein 21 [Homo sapiens] 47 1e-05
gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens] 42 4e-04
gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens] 42 4e-04
gi|22749269 ring finger protein 129 [Homo sapiens] 42 6e-04
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 40 0.001
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 40 0.001
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 40 0.001
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 40 0.001
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 40 0.001
gi|45446749 kinesin family member 5A [Homo sapiens] 39 0.003
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 39 0.003
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens] 39 0.003
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 39 0.004
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 39 0.005
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 39 0.005
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 38 0.006
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 38 0.006
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 38 0.006
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 38 0.006
gi|14195599 protein phosphatase 1, regulatory (inhibitor) subuni... 38 0.006
gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens] 38 0.006
gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens] 38 0.006
gi|27436948 lamin A/C isoform 3 [Homo sapiens] 37 0.011
gi|5031875 lamin A/C isoform 2 [Homo sapiens] 37 0.011
>gi|221139693 hypothetical protein LOC199870 isoform 5 [Homo
sapiens]
Length = 227
Score = 460 bits (1184), Expect = e-130
Identities = 227/227 (100%), Positives = 227/227 (100%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
Query: 61 NVQLYGTVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS 120
NVQLYGTVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS
Sbjct: 61 NVQLYGTVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS 120
Query: 121 FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM 180
FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM
Sbjct: 121 FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM 180
Query: 181 RAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 227
RAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP
Sbjct: 181 RAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 227
>gi|219881540 hypothetical protein LOC199870 isoform 4 [Homo
sapiens]
Length = 278
Score = 436 bits (1122), Expect = e-123
Identities = 227/278 (81%), Positives = 227/278 (81%), Gaps = 51/278 (18%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
Query: 61 NVQLYGT---------------------------------------------------VD 69
NVQLYGT VD
Sbjct: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
Query: 70 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDS 129
GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDS
Sbjct: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDS 180
Query: 130 PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEK 189
PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEK
Sbjct: 181 PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEK 240
Query: 190 THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 227
THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP
Sbjct: 241 THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 278
>gi|22749341 hypothetical protein LOC199870 isoform 3 [Homo sapiens]
Length = 307
Score = 421 bits (1082), Expect = e-118
Identities = 227/307 (73%), Positives = 227/307 (73%), Gaps = 80/307 (26%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
Query: 61 NVQLYGT---------------------------------------------------VD 69
NVQLYGT VD
Sbjct: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
Query: 70 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS--------- 120
GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS
Sbjct: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI 180
Query: 121 --------------------FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 160
FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL
Sbjct: 181 QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 240
Query: 161 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 220
EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK
Sbjct: 241 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 300
Query: 221 SGAITSP 227
SGAITSP
Sbjct: 301 SGAITSP 307
>gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo
sapiens]
Length = 312
Score = 417 bits (1072), Expect = e-117
Identities = 226/312 (72%), Positives = 226/312 (72%), Gaps = 85/312 (27%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQES----------- 49
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQE
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQERLECNGTISAHC 60
Query: 50 -----------------------KTNTICKKCAQNVQLYGT------------------- 67
KTNTICKKCAQNVQLYGT
Sbjct: 61 NLHLPGSSDSPASSSRVAGITGIKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 120
Query: 68 --------------------------------VDGKLLCWLCTLSYKRVLQKTKEQRKHL 95
VDGKLLCWLCTLSYKRVLQKTKEQRKHL
Sbjct: 121 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 180
Query: 96 SSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQK 155
SSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQK
Sbjct: 181 SSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQK 240
Query: 156 DQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKS 215
DQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKS
Sbjct: 241 DQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKS 300
Query: 216 KKSEKSGAITSP 227
KKSEKSGAITSP
Sbjct: 301 KKSEKSGAITSP 312
>gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo
sapiens]
Length = 341
Score = 402 bits (1032), Expect = e-112
Identities = 226/341 (66%), Positives = 226/341 (66%), Gaps = 114/341 (33%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQES----------- 49
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQE
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQERLECNGTISAHC 60
Query: 50 -----------------------KTNTICKKCAQNVQLYGT------------------- 67
KTNTICKKCAQNVQLYGT
Sbjct: 61 NLHLPGSSDSPASSSRVAGITGIKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 120
Query: 68 --------------------------------VDGKLLCWLCTLSYKRVLQKTKEQRKHL 95
VDGKLLCWLCTLSYKRVLQKTKEQRKHL
Sbjct: 121 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 180
Query: 96 SSSSRAGHQEKEQYSRLSGGGHYNS-----------------------------FSPDLA 126
SSSSRAGHQEKEQYSRLSGGGHYNS FSPDLA
Sbjct: 181 SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLA 240
Query: 127 LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ 186
LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ
Sbjct: 241 LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ 300
Query: 187 MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 227
MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP
Sbjct: 301 MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 341
>gi|134288896 hypothetical protein LOC143684 [Homo sapiens]
Length = 339
Score = 284 bits (726), Expect = 5e-77
Identities = 169/336 (50%), Positives = 195/336 (58%), Gaps = 110/336 (32%)
Query: 2 AALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQN 61
+ALYACTKC QR+PFE LSQGQQLCKECRIAHP+VKCTYCR+E+QQESKTNTICKKCAQN
Sbjct: 4 SALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQN 63
Query: 62 VQLYGT----------------------------------------------------VD 69
V+ +GT VD
Sbjct: 64 VKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVD 123
Query: 70 GKLLCWLCTLSYKRVLQKTKEQRKHL----SSSSRAGHQEKEQ------------YSRLS 113
GKLLCWLCTLSYKRVLQKTKEQRK L S+SS + EK+Q + R S
Sbjct: 124 GKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHHRHS 183
Query: 114 GGGHY-----------------------------------------NSFSPDLALDSPGT 132
H +S S + + DS GT
Sbjct: 184 SSHHKISNLSPEEEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSSINQSADSGGT 243
Query: 133 DHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHK 192
D+FV+I+QLKEEV +LK++L Q+DQ ILEK+KK+TELKADFQYQES +R KMN MEK HK
Sbjct: 244 DNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHK 303
Query: 193 EVTEQLQAKNRELLKQAAALSKSKKSEKSGAI-TSP 227
E EQLQAKNRELLKQ AALSK KK +KSG+I TSP
Sbjct: 304 ETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP 339
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 47.4 bits (111), Expect = 1e-05
Identities = 53/238 (22%), Positives = 103/238 (43%), Gaps = 38/238 (15%)
Query: 7 CTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCA---QNVQ 63
C C QRF + L +QL E QE++ T ++CA + +
Sbjct: 51 CPVCRQRFLLKNLRPNRQLANMVNNLK----------EISQEAREGTQGERCAVHGERLH 100
Query: 64 LYGTVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSP 123
L+ DGK LCW+C ++++ R H QE ++ +++ G
Sbjct: 101 LFCEKDGKALCWVCA--------QSRKHRDHAMVPLEEAAQEYQEKLQVALGELRR--KQ 150
Query: 124 DLALDSPGTDHFVIIAQLKEEVATLKKMLH-----QKDQMILEKEKKITELKADFQYQ-- 176
+LA + + + A K+ V T K +H QK+ ++ E+++++ EL+ D + Q
Sbjct: 151 ELA-EKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLR 209
Query: 177 -----ESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKS--EKSGAITSP 227
E+++ + +++ E+ + + ELL++ + + +S K ITSP
Sbjct: 210 ILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLERSESWNLKDLDITSP 267
>gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens]
Length = 1019
Score = 42.0 bits (97), Expect = 4e-04
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 8/87 (9%)
Query: 141 LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQA 200
+KEE+A LK L+ +LEKEKK ELK +E+Q +A + +E EV EQ +
Sbjct: 815 MKEEMAELKAQLY-----LLEKEKKALELK--LSTREAQEQAYLVHIEHLKSEVEEQKEQ 867
Query: 201 KNRELLKQAAALSKSKKSEKSGAITSP 227
+ R L ++ SK K ++ SP
Sbjct: 868 RMRSLSSTSSG-SKDKPGKECADAASP 893
>gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens]
Length = 829
Score = 42.0 bits (97), Expect = 4e-04
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 8/87 (9%)
Query: 141 LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQA 200
+KEE+A LK L+ +LEKEKK ELK +E+Q +A + +E EV EQ +
Sbjct: 625 MKEEMAELKAQLY-----LLEKEKKALELK--LSTREAQEQAYLVHIEHLKSEVEEQKEQ 677
Query: 201 KNRELLKQAAALSKSKKSEKSGAITSP 227
+ R L ++ SK K ++ SP
Sbjct: 678 RMRSLSSTSSG-SKDKPGKECADAASP 703
>gi|22749269 ring finger protein 129 [Homo sapiens]
Length = 471
Score = 41.6 bits (96), Expect = 6e-04
Identities = 52/228 (22%), Positives = 97/228 (42%), Gaps = 43/228 (18%)
Query: 5 YACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQL 64
+ C C FP+++ + QL IA K R ++ K N +C+K Q + L
Sbjct: 51 FPCPVCRFCFPYKSFRRNPQLRNLTEIA----KQLQIRRSKRKRQKENAMCEKHNQFLTL 106
Query: 65 YGTVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPD 124
+ D ++LC C+ S TK Q+ ++ +A +E L G S +
Sbjct: 107 FCVKDLEILCTQCSFS-------TKHQKHYICPIKKAASYHRE---ILEG-------SLE 149
Query: 125 LALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQ---------MILEKEKKITELKADFQY 175
++ VII Q + V KK+ +++++ + L+ E+++ + Q
Sbjct: 150 PLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEFEQIRLFLQNEQEM--ILRQIQD 207
Query: 176 QESQMRAKMNQ-------MEKTHKEVTEQLQAK----NRELLKQAAAL 212
+E + AK+N+ T K + +++ K N ELL QA ++
Sbjct: 208 EEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSNLELLTQAKSM 255
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 40.4 bits (93), Expect = 0.001
Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 85 LQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---IAQL 141
L+K KE+ K + A +++E+ R +S S D+ +F++ IA L
Sbjct: 386 LKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAM-YGNFMLKKDIAML 444
Query: 142 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 201
KEE+ +K +K++ +++ K ITE+ A+F E +R + KT ++QL
Sbjct: 445 KEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEKMITKTVARYSQQLNDL 501
Query: 202 NRELLKQAAALSKSKKSEK 220
E + + L K K +++
Sbjct: 502 KAENARLNSELEKEKHNKE 520
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 40.4 bits (93), Expect = 0.001
Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 85 LQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---IAQL 141
L+K KE+ K + A +++E+ R +S S D+ +F++ IA L
Sbjct: 279 LKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAM-YGNFMLKKDIAML 337
Query: 142 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 201
KEE+ +K +K++ +++ K ITE+ A+F E +R + KT ++QL
Sbjct: 338 KEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEKMITKTVARYSQQLNDL 394
Query: 202 NRELLKQAAALSKSKKSEK 220
E + + L K K +++
Sbjct: 395 KAENARLNSELEKEKHNKE 413
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 40.4 bits (93), Expect = 0.001
Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 85 LQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---IAQL 141
L+K KE+ K + A +++E+ R +S S D+ +F++ IA L
Sbjct: 386 LKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAM-YGNFMLKKDIAML 444
Query: 142 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 201
KEE+ +K +K++ +++ K ITE+ A+F E +R + KT ++QL
Sbjct: 445 KEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEKMITKTVARYSQQLNDL 501
Query: 202 NRELLKQAAALSKSKKSEK 220
E + + L K K +++
Sbjct: 502 KAENARLNSELEKEKHNKE 520
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 40.4 bits (93), Expect = 0.001
Identities = 17/84 (20%), Positives = 48/84 (57%)
Query: 136 VIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVT 195
V + ++++ +TL + H K +++ E ++ E+K F+ +E +++A+ ++ + K
Sbjct: 798 VELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAM 857
Query: 196 EQLQAKNRELLKQAAALSKSKKSE 219
E+L + + +Q A+ ++ ++E
Sbjct: 858 EKLHSMDDAFKRQVDAIVEAHQAE 881
Score = 33.9 bits (76), Expect = 0.12
Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 9/74 (12%)
Query: 137 IIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTE 196
II E + LK L +KD+ I ++KITE++ + + Q+ K +Q++ EV E
Sbjct: 725 IIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIE---KCTQEQLDEKSSQLD----EVLE 777
Query: 197 QLQAKN--RELLKQ 208
+L+ N +E LKQ
Sbjct: 778 KLERHNERKEKLKQ 791
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 40.4 bits (93), Expect = 0.001
Identities = 17/84 (20%), Positives = 48/84 (57%)
Query: 136 VIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVT 195
V + ++++ +TL + H K +++ E ++ E+K F+ +E +++A+ ++ + K
Sbjct: 891 VELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAM 950
Query: 196 EQLQAKNRELLKQAAALSKSKKSE 219
E+L + + +Q A+ ++ ++E
Sbjct: 951 EKLHSMDDAFKRQVDAIVEAHQAE 974
Score = 33.9 bits (76), Expect = 0.12
Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 9/74 (12%)
Query: 137 IIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTE 196
II E + LK L +KD+ I ++KITE++ + + Q+ K +Q++ EV E
Sbjct: 818 IIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIE---KCTQEQLDEKSSQLD----EVLE 870
Query: 197 QLQAKN--RELLKQ 208
+L+ N +E LKQ
Sbjct: 871 KLERHNERKEKLKQ 884
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 39.3 bits (90), Expect = 0.003
Identities = 40/169 (23%), Positives = 79/169 (46%), Gaps = 18/169 (10%)
Query: 48 ESKTNTICKKCAQNVQLYGTVDGKLLCWLCTLSYKRVLQKTKEQRKHLS------SSSRA 101
E+K+ + + A+ ++ +V+ +L Y++ +KTK Q++ ++ S R
Sbjct: 313 ETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRN 372
Query: 102 GHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQL--------KEEVATLKKMLH 153
G E RL+G + +L ++P D+ I+ ++ +EE+ L K L
Sbjct: 373 GENVPET-ERLAG--EEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLD 429
Query: 154 QKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKN 202
KD I ++ + I +LK QE + + EK +E++ LQ++N
Sbjct: 430 DKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELS-HLQSEN 477
Score = 28.9 bits (63), Expect = 3.8
Identities = 16/100 (16%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 124 DLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAK 183
+L ++S H +A+L++E+ +K + + + + + ++ +L+AD++ +S+ K
Sbjct: 700 ELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEK 759
Query: 184 MNQME------KTHKEVTEQLQAKNRELLKQAAALSKSKK 217
+++ + H++ + L+ + ++ L +K
Sbjct: 760 STKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRK 799
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 39.3 bits (90), Expect = 0.003
Identities = 25/94 (26%), Positives = 50/94 (53%), Gaps = 10/94 (10%)
Query: 140 QLKEEVATLKKMLHQKDQMILE------KEKKITEL----KADFQYQESQMRAKMNQMEK 189
+++ V L+K+ +K+ ++ E K K+++ K++F+ + + +A + +EK
Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEK 892
Query: 190 THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGA 223
T KE+ QLQ + LK+ L KS + EK +
Sbjct: 893 TCKELKHQLQVQMENTLKEQKELKKSLEKEKEAS 926
Score = 34.7 bits (78), Expect = 0.069
Identities = 30/144 (20%), Positives = 66/144 (45%), Gaps = 6/144 (4%)
Query: 81 YKRVLQKTKEQRKH---LSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI 137
+K++ Q+ +E+ +H L S H + + R G H D
Sbjct: 395 FKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQ 454
Query: 138 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMR---AKMNQMEKTHKEV 194
+A L+ +++ L++ L +K E + ++ + K Q Q++ + AK+ + + ++V
Sbjct: 455 VADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQV 514
Query: 195 TEQLQAKNRELLKQAAALSKSKKS 218
Q+ K++++ A L KSK++
Sbjct: 515 LRQIGDKDQKIQNLEALLQKSKEN 538
Score = 33.1 bits (74), Expect = 0.20
Identities = 22/91 (24%), Positives = 52/91 (57%), Gaps = 10/91 (10%)
Query: 137 IIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM---RAKMNQME----K 189
+I +LK ATL++ +K+Q + E+ K + +++ + +E ++ ++K+ ++E +
Sbjct: 1076 LIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCR 1135
Query: 190 THKEVT---EQLQAKNRELLKQAAALSKSKK 217
KE+T E+L++ E +K+ L +K+
Sbjct: 1136 QEKEITKLNEELKSHKLESIKEITNLKDAKQ 1166
Score = 31.6 bits (70), Expect = 0.58
Identities = 41/186 (22%), Positives = 76/186 (40%), Gaps = 21/186 (11%)
Query: 46 QQESKTNTICKKCAQNVQLYGTVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQE 105
Q +S+ N + K + + G G+L LS ++++ K ++ SR Q
Sbjct: 411 QLQSEINQLHSKLLETERQLGEAHGRLKEQR-QLSSEKLMDKEQQVADLQLKLSRLEEQL 469
Query: 106 KEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILE---K 162
KE+ + NS LD H A + A L++ + +Q++ + K
Sbjct: 470 KEKVT--------NSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDK 521
Query: 163 EKKITELKADFQYQESQMRAKMNQMEKTHKE---------VTEQLQAKNRELLKQAAALS 213
++KI L+A Q + + + E + + V QLQ KN L +Q L+
Sbjct: 522 DQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLT 581
Query: 214 KSKKSE 219
+ K++
Sbjct: 582 EKLKNQ 587
Score = 30.8 bits (68), Expect = 0.99
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 143 EEVATLKKMLHQ----KDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 198
E+VA LKK L Q D M LE+E++ +LK + + +SQ + E T ++ +L
Sbjct: 221 EDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASS----EATISQLRSEL 276
Query: 199 QAKNRELLKQAAALSKSKKS 218
+E+ L K K S
Sbjct: 277 AKGPQEVAVYVQELQKLKSS 296
Score = 30.0 bits (66), Expect = 1.7
Identities = 19/81 (23%), Positives = 43/81 (53%), Gaps = 13/81 (16%)
Query: 140 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ 199
QLK E+ ++++ L Q + + EK +E Q++ +N+++++ ++ +Q++
Sbjct: 928 QLKLELNSMQEQLIQAQNTLKQNEK-----------EEQQLQGNINELKQSSEQKKKQIE 976
Query: 200 AKNRELLKQAAALSKSKKSEK 220
A EL + A L K++ K
Sbjct: 977 ALQGEL--KIAVLQKTELENK 995
Score = 29.6 bits (65), Expect = 2.2
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 8/78 (10%)
Query: 138 IAQLKEEVATLKKMLHQKDQMILEKEK-------KITELKADFQYQESQMRAKMNQMEKT 190
I L E + T+KK + + E EK +I L+A Q + + RA + + K
Sbjct: 1243 ITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKG 1302
Query: 191 HKEVTEQLQAKNRELLKQ 208
E+ E+LQ K EL ++
Sbjct: 1303 EGEI-EKLQTKVLELQRK 1319
Score = 28.9 bits (63), Expect = 3.8
Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 81 YKRVLQKTKE---QRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI 137
Y + QKT+E Q K L + S KEQ L + DL L + T+
Sbjct: 718 YLSLEQKTEELEGQIKKLEADSLEVKASKEQ--ALQDLQQQRQLNTDLELRA--TELSKQ 773
Query: 138 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 197
+ KE V++ + L +K + + ++K+T+ + + Q + + + H+E+ +
Sbjct: 774 LEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNR 833
Query: 198 LQAKNRELLK 207
+Q EL K
Sbjct: 834 IQTTVTELQK 843
Score = 27.7 bits (60), Expect = 8.4
Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Query: 142 KEEVATLKKMLHQKDQMILEKEKKITELKADFQ-YQESQMRAKMNQMEKTHKEVT--EQL 198
KE+V+ L + K +++L E T +AD Q + ++ A ++ ++ +K T +Q+
Sbjct: 634 KEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQV 693
Query: 199 QAKNRELLKQAAALSKSKKSEK 220
AK ++ + + L K K
Sbjct: 694 TAKLQDKQEHCSQLESHLKEYK 715
>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
Length = 500
Score = 39.3 bits (90), Expect = 0.003
Identities = 42/217 (19%), Positives = 87/217 (40%), Gaps = 46/217 (21%)
Query: 7 CTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTI--------CKKC 58
C C Q F L + C EC++ CT+ + K + C +
Sbjct: 61 CEACIQ--DFWRLQAKETFCPECKMLCQYNNCTFNPVLDKLVEKIKKLPLLKGHPQCPEH 118
Query: 59 AQNVQLYGTVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHY 118
+N++L+ DGKL+C+ C +R + +++ ++S H+
Sbjct: 119 GENLKLFSKPDGKLICFQC-------------------KDARLSVGQSKEFLQISDAVHF 159
Query: 119 NSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKI-------TELKA 171
F+ +LA+ + + +E+ TL+ M QK+ + KE K+ E
Sbjct: 160 --FTEELAIQQGQLETTL------KELQTLRNM--QKEAIAAHKENKLHLQQHVSMEFLK 209
Query: 172 DFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQ 208
Q+ S+ + + ++ + K + E+++ +L +Q
Sbjct: 210 LHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQ 246
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 38.9 bits (89), Expect = 0.004
Identities = 41/137 (29%), Positives = 58/137 (42%), Gaps = 12/137 (8%)
Query: 81 YKRVLQKT-KEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPD-LALDSPGTDHFVII 138
Y +VL +T E+ ++S G K + SG +S D LA D +
Sbjct: 313 YSKVLCQTLSERNSEITSLKNEGENLKRDNAITSG--MVSSLQKDILAKDEQ-------V 363
Query: 139 AQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 198
QLKEEV+ LK KD + + + LK + + QE R EK K Q+
Sbjct: 364 QQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEELK-QEDAHRELREAQEKELKLCKTQI 422
Query: 199 QAKNRELLKQAAALSKS 215
Q +E+ K A L KS
Sbjct: 423 QDMEKEMKKLRAELRKS 439
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 38.5 bits (88), Expect = 0.005
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 11/82 (13%)
Query: 142 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 201
KEE+ + ++ + + I+E+EKK ELK K+ +K E+ EQ+ K
Sbjct: 321 KEEIQEKETIIEELNTKIIEEEKKTLELKD-----------KLTTADKLLGELQEQIVQK 369
Query: 202 NRELLKQAAALSKSKKSEKSGA 223
N+E+ L+ SK+ E+ +
Sbjct: 370 NQEIKNMKLELTNSKQKERQSS 391
Score = 31.2 bits (69), Expect = 0.76
Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 140 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ 199
+LK+++ T K+L + + I++K ++I +K + + + R ++++ V E+LQ
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTV-EELQ 405
Query: 200 AKNRE 204
+N +
Sbjct: 406 KRNHK 410
Score = 31.2 bits (69), Expect = 0.76
Identities = 41/176 (23%), Positives = 78/176 (44%), Gaps = 31/176 (17%)
Query: 53 TICKKCAQNVQLYGTVDGKLLCWLCTLSYKRV--LQKTKEQRKHLSSSSRAGHQEKEQYS 110
T C K +++Q G + ++L K++ LQK E++ + S+ + ++Y+
Sbjct: 2516 TQCYKQIKDMQEQGQFETEML-------QKKIVNLQKIVEEKVAAALVSQIQLEAVQEYA 2568
Query: 111 RLSGGGHYNSFSPD---------LALDSPGTDHFVI---IAQLKEEVATLK-KMLHQKDQ 157
+ S P+ L D G+D + I++L+ +V + ++ +K+Q
Sbjct: 2569 KFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQ 2628
Query: 158 M------ILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEV---TEQLQAKNRE 204
+ +LEKEKK+ EL+ + E + R K + EV T +L N E
Sbjct: 2629 VEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEE 2684
Score = 30.8 bits (68), Expect = 0.99
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 142 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 201
K E TL+ QK+ IL +E+K K + + +++ K +EK KE LQ K
Sbjct: 713 KSEEMTLQINELQKEIEILRQEEKE---KGTLEQEVQELQLKTELLEKQMKEKENDLQEK 769
Query: 202 NRELLKQAAALSKSKKS 218
+L + + L KK+
Sbjct: 770 FAQLEAENSILKDEKKT 786
Score = 29.3 bits (64), Expect = 2.9
Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
Query: 138 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 197
I + K+ V T+ + + KD+ + ++ E+ Q+ Q+E +E+ Q
Sbjct: 1538 IPESKDCVLTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQ 1597
Query: 198 LQAKNR--ELLKQAAALSKSKKSE 219
Q + ELL+QA ++ E
Sbjct: 1598 YQEHQQATELLRQAHMRQMERQRE 1621
Score = 28.5 bits (62), Expect = 4.9
Identities = 21/95 (22%), Positives = 51/95 (53%), Gaps = 10/95 (10%)
Query: 135 FVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM------RAKMNQME 188
F++ + +E++ + M + M+ E++ + + QYQE Q +A M QME
Sbjct: 1559 FIVRQSIHDEIS-VSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQME 1617
Query: 189 KTHKE---VTEQLQAKNRELLKQAAALSKSKKSEK 220
+ ++ + E+++ NR+L ++++ +++ SE+
Sbjct: 1618 RQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSER 1652
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 38.5 bits (88), Expect = 0.005
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 11/82 (13%)
Query: 142 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 201
KEE+ + ++ + + I+E+EKK ELK K+ +K E+ EQ+ K
Sbjct: 321 KEEIQEKETIIEELNTKIIEEEKKTLELKD-----------KLTTADKLLGELQEQIVQK 369
Query: 202 NRELLKQAAALSKSKKSEKSGA 223
N+E+ L+ SK+ E+ +
Sbjct: 370 NQEIKNMKLELTNSKQKERQSS 391
Score = 31.2 bits (69), Expect = 0.76
Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 140 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ 199
+LK+++ T K+L + + I++K ++I +K + + + R ++++ V E+LQ
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTV-EELQ 405
Query: 200 AKNRE 204
+N +
Sbjct: 406 KRNHK 410
Score = 31.2 bits (69), Expect = 0.76
Identities = 41/176 (23%), Positives = 78/176 (44%), Gaps = 31/176 (17%)
Query: 53 TICKKCAQNVQLYGTVDGKLLCWLCTLSYKRV--LQKTKEQRKHLSSSSRAGHQEKEQYS 110
T C K +++Q G + ++L K++ LQK E++ + S+ + ++Y+
Sbjct: 2508 TQCYKQIKDMQEQGQFETEML-------QKKIVNLQKIVEEKVAAALVSQIQLEAVQEYA 2560
Query: 111 RLSGGGHYNSFSPD---------LALDSPGTDHFVI---IAQLKEEVATLK-KMLHQKDQ 157
+ S P+ L D G+D + I++L+ +V + ++ +K+Q
Sbjct: 2561 KFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLRISELESQVVEMHTSLILEKEQ 2620
Query: 158 M------ILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEV---TEQLQAKNRE 204
+ +LEKEKK+ EL+ + E + R K + EV T +L N E
Sbjct: 2621 VEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEE 2676
Score = 30.8 bits (68), Expect = 0.99
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 142 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 201
K E TL+ QK+ IL +E+K K + + +++ K +EK KE LQ K
Sbjct: 713 KSEEMTLQINELQKEIEILRQEEKE---KGTLEQEVQELQLKTELLEKQMKEKENDLQEK 769
Query: 202 NRELLKQAAALSKSKKS 218
+L + + L KK+
Sbjct: 770 FAQLEAENSILKDEKKT 786
Score = 29.3 bits (64), Expect = 2.9
Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
Query: 138 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 197
I + K+ V T+ + + KD+ + ++ E+ Q+ Q+E +E+ Q
Sbjct: 1538 IPESKDCVLTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQ 1597
Query: 198 LQAKNR--ELLKQAAALSKSKKSE 219
Q + ELL+QA ++ E
Sbjct: 1598 YQEHQQATELLRQAHMRQMERQRE 1621
Score = 28.5 bits (62), Expect = 4.9
Identities = 21/95 (22%), Positives = 51/95 (53%), Gaps = 10/95 (10%)
Query: 135 FVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM------RAKMNQME 188
F++ + +E++ + M + M+ E++ + + QYQE Q +A M QME
Sbjct: 1559 FIVRQSIHDEIS-VSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQME 1617
Query: 189 KTHKE---VTEQLQAKNRELLKQAAALSKSKKSEK 220
+ ++ + E+++ NR+L ++++ +++ SE+
Sbjct: 1618 RQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSER 1652
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 38.1 bits (87), Expect = 0.006
Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Query: 82 KRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---I 138
++ L+K KE K + A +++E+ R +S S D +F++ I
Sbjct: 384 RKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEM-FGNFMLKRDI 442
Query: 139 AQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 198
A LKEE+ +K +K++ +++ K ITE+ A+F E +R + K + ++QL
Sbjct: 443 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEEMITKKVAQYSQQL 499
Query: 199 QAKNRELLKQAAALSKSKKSEK 220
E + + L K K +++
Sbjct: 500 NDLKAENARLNSKLEKEKHNKE 521
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 38.1 bits (87), Expect = 0.006
Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Query: 82 KRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---I 138
++ L+K KE K + A +++E+ R +S S D +F++ I
Sbjct: 413 RKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEM-FGNFMLKRDI 471
Query: 139 AQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 198
A LKEE+ +K +K++ +++ K ITE+ A+F E +R + K + ++QL
Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEEMITKKVAQYSQQL 528
Query: 199 QAKNRELLKQAAALSKSKKSEK 220
E + + L K K +++
Sbjct: 529 NDLKAENARLNSKLEKEKHNKE 550
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 38.1 bits (87), Expect = 0.006
Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Query: 82 KRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---I 138
++ L+K KE K + A +++E+ R +S S D +F++ I
Sbjct: 413 RKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEM-FGNFMLKRDI 471
Query: 139 AQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 198
A LKEE+ +K +K++ +++ K ITE+ A+F E +R + K + ++QL
Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEEMITKKVAQYSQQL 528
Query: 199 QAKNRELLKQAAALSKSKKSEK 220
E + + L K K +++
Sbjct: 529 NDLKAENARLNSKLEKEKHNKE 550
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 38.1 bits (87), Expect = 0.006
Identities = 28/106 (26%), Positives = 58/106 (54%), Gaps = 15/106 (14%)
Query: 128 DSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRA---KM 184
+S T++ + +L+E L + + +++ +K++K ++ + + ++ + RA KM
Sbjct: 887 ESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKM 946
Query: 185 NQMEK------------THKEVTEQLQAKNRELLKQAAALSKSKKS 218
++ME+ T K++ EQLQA+NR L + A LS+S +S
Sbjct: 947 SEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIES 992
>gi|14195599 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform d [Homo sapiens]
Length = 224
Score = 38.1 bits (87), Expect = 0.006
Identities = 28/106 (26%), Positives = 58/106 (54%), Gaps = 15/106 (14%)
Query: 128 DSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRA---KM 184
+S T++ + +L+E L + + +++ +K++K ++ + + ++ + RA KM
Sbjct: 113 ESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKM 172
Query: 185 NQMEK------------THKEVTEQLQAKNRELLKQAAALSKSKKS 218
++ME+ T K++ EQLQA+NR L + A LS+S +S
Sbjct: 173 SEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIES 218
>gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens]
Length = 348
Score = 38.1 bits (87), Expect = 0.006
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 17/90 (18%)
Query: 141 LKEEVATLKKMLHQKDQMILEKEKKITELK-------------ADFQYQESQMRAKMNQM 187
L+E++ +LK++L K+Q I E+EKKI EL+ Q Q ++A+++Q
Sbjct: 214 LEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQ- 272
Query: 188 EKTHKEVTEQLQAKNRELLKQAAALSKSKK 217
+ VT QL +N L + ++ KK
Sbjct: 273 ---NTVVTRQLSEENANLQEYVEKETQEKK 299
>gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens]
Length = 1379
Score = 38.1 bits (87), Expect = 0.006
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 17/90 (18%)
Query: 141 LKEEVATLKKMLHQKDQMILEKEKKITELK-------------ADFQYQESQMRAKMNQM 187
L+E++ +LK++L K+Q I E+EKKI EL+ Q Q ++A+++Q
Sbjct: 1245 LEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQ- 1303
Query: 188 EKTHKEVTEQLQAKNRELLKQAAALSKSKK 217
+ VT QL +N L + ++ KK
Sbjct: 1304 ---NTVVTRQLSEENANLQEYVEKETQEKK 1330
>gi|27436948 lamin A/C isoform 3 [Homo sapiens]
Length = 634
Score = 37.4 bits (85), Expect = 0.011
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 4/123 (3%)
Query: 83 RVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLK 142
+V Q KE K S+ Q E+ S L G H + +DS ++QL+
Sbjct: 255 QVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQ----LSQLQ 310
Query: 143 EEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKN 202
+++A + L + + + L A+ + + ++MRA+M Q ++E+ + A +
Sbjct: 311 KQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALD 370
Query: 203 REL 205
E+
Sbjct: 371 MEI 373
>gi|5031875 lamin A/C isoform 2 [Homo sapiens]
Length = 572
Score = 37.4 bits (85), Expect = 0.011
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 4/123 (3%)
Query: 83 RVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLK 142
+V Q KE K S+ Q E+ S L G H + +DS ++QL+
Sbjct: 255 QVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQ----LSQLQ 310
Query: 143 EEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKN 202
+++A + L + + + L A+ + + ++MRA+M Q ++E+ + A +
Sbjct: 311 KQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALD 370
Query: 203 REL 205
E+
Sbjct: 371 MEI 373
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.126 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,347,795
Number of Sequences: 37866
Number of extensions: 360300
Number of successful extensions: 4088
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 358
Number of HSP's that attempted gapping in prelim test: 2869
Number of HSP's gapped (non-prelim): 1555
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.