Search of human proteins with 22035694

Search of human proteins with 22035694

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo
sapiens]
         (400 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo sap...   848   0.0  
gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo sap...   204   1e-52
gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein ...   192   6e-49
gi|224282178 GDNF family receptor alpha 1 isoform b preproprotei...   191   1e-48
gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein...   191   1e-48
gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Ho...   151   9e-37
gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Ho...   105   7e-23
gi|148231468 GDNF family receptor alpha like [Homo sapiens]            67   3e-11
gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2 ...    64   2e-10
gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2 ...    56   5e-08
gi|54873613 agrin [Homo sapiens]                                       38   0.014
gi|169212906 PREDICTED: NPIP-like protein ENSP00000283050 isofor...    33   0.35 
gi|4759336 Fanconi anemia, complementation group G [Homo sapiens]      33   0.35 
gi|33598912 activin A receptor, type IB isoform c precursor [Hom...    33   0.46 
gi|33598910 activin A receptor, type IB isoform b precursor [Hom...    33   0.46 
gi|4757720 activin A receptor, type IB isoform a precursor [Homo...    33   0.46 
gi|209862789 microtubule associated monoxygenase, calponin and L...    33   0.46 
gi|239745496 PREDICTED: hypothetical protein XP_002343477 [Homo ...    33   0.60 
gi|239745482 PREDICTED: hypothetical protein [Homo sapiens]            33   0.60 
gi|239745475 PREDICTED: similar to NPIP-like protein ENSP0000028...    33   0.60 
gi|239745469 PREDICTED: nuclear pore complex interacting protein...    33   0.60 
gi|63053517 keratin associated protein 10-5 [Homo sapiens]             33   0.60 
gi|11386139 phospholipase C beta 3 [Homo sapiens]                      32   0.78 
gi|54607018 RYK receptor-like tyrosine kinase isoform 2 [Homo sa...    32   1.0  
gi|54607020 RYK receptor-like tyrosine kinase isoform 1 [Homo sa...    32   1.0  
gi|194097442 protein tyrosine phosphatase, receptor type, N poly...    32   1.3  
gi|194097440 protein tyrosine phosphatase, receptor type, N poly...    32   1.3  
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 31   1.7  
gi|187607437 hypothetical protein LOC27013 [Homo sapiens]              31   1.7  
gi|13376335 hypothetical protein LOC79946 [Homo sapiens]               31   1.7  

>gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo
           sapiens]
          Length = 400

 Score =  848 bits (2190), Expect = 0.0
 Identities = 400/400 (100%), Positives = 400/400 (100%)

Query: 1   MVRPLNPRPLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMNSCLQARRKCQADPTCSAA 60
           MVRPLNPRPLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMNSCLQARRKCQADPTCSAA
Sbjct: 1   MVRPLNPRPLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMNSCLQARRKCQADPTCSAA 60

Query: 61  YHHLDSCTSSISTPLPSEEPSVPADCLEAAQQLRNSSLIGCMCHRRMKNQVACLDIYWTV 120
           YHHLDSCTSSISTPLPSEEPSVPADCLEAAQQLRNSSLIGCMCHRRMKNQVACLDIYWTV
Sbjct: 61  YHHLDSCTSSISTPLPSEEPSVPADCLEAAQQLRNSSLIGCMCHRRMKNQVACLDIYWTV 120

Query: 121 HRARSLGNYELDVSPYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTLNDKCDRLRK 180
           HRARSLGNYELDVSPYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTLNDKCDRLRK
Sbjct: 121 HRARSLGNYELDVSPYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTLNDKCDRLRK 180

Query: 181 AYGEACSGPHCQRHVCLRQLLTFFEKAAEPHAQGLLLCPCAPNDRGCGERRRNTIAPNCA 240
           AYGEACSGPHCQRHVCLRQLLTFFEKAAEPHAQGLLLCPCAPNDRGCGERRRNTIAPNCA
Sbjct: 181 AYGEACSGPHCQRHVCLRQLLTFFEKAAEPHAQGLLLCPCAPNDRGCGERRRNTIAPNCA 240

Query: 241 LPPVAPNCLELRRLCFSDPLCRSRLVDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAM 300
           LPPVAPNCLELRRLCFSDPLCRSRLVDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAM
Sbjct: 241 LPPVAPNCLELRRLCFSDPLCRSRLVDFQTHCHPMDILGTCATEQSRCLRAYLGLIGTAM 300

Query: 301 TPNFVSNVNTSVALSCTCRGSGNLQEECEMLEGFFSHNPCLTEAIAAKMRFHSQLFSQDW 360
           TPNFVSNVNTSVALSCTCRGSGNLQEECEMLEGFFSHNPCLTEAIAAKMRFHSQLFSQDW
Sbjct: 301 TPNFVSNVNTSVALSCTCRGSGNLQEECEMLEGFFSHNPCLTEAIAAKMRFHSQLFSQDW 360

Query: 361 PHPTFAVMAHQNENPAVRPQPWVPSLFSCTLPLILLLSLW 400
           PHPTFAVMAHQNENPAVRPQPWVPSLFSCTLPLILLLSLW
Sbjct: 361 PHPTFAVMAHQNENPAVRPQPWVPSLFSCTLPLILLLSLW 400


>gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo
           sapiens]
          Length = 464

 Score =  204 bits (518), Expect = 1e-52
 Identities = 116/323 (35%), Positives = 164/323 (50%), Gaps = 27/323 (8%)

Query: 44  CLQARRKCQADPTCSAAYHHLDSCTSSI--STPLPSEEPSVPADCLEAAQQLRNSSLIGC 101
           C++A   C A+  CS+ Y  L  C +    +T L ++E      C  A + L+ S L  C
Sbjct: 40  CVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKE------CQAALEVLQESPLYDC 93

Query: 102 MCHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYEDTVTSKPWKMNLSKL-------NM 154
            C R MK ++ CL IYW++H   + G    + SPYE   +       L+ +        +
Sbjct: 94  RCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADPV 153

Query: 155 LKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACS-----GPHCQRHVCLRQLLTFFEKAAE 209
           +   S+ CL  A  C LND C +LR +Y   C+        C R  C + L  FF++   
Sbjct: 154 VSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPS 213

Query: 210 PHAQGLLLCPCAPNDRGCGERRRNTIAPNCAL-PPVAPNCLELRRLCFSDPLCRSRLVDF 268
            +   +L C C   D+ C ERRR TI P+C+      PNCL+LR +C +D LCRSRL DF
Sbjct: 214 EYTYRMLFCSC--QDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADF 271

Query: 269 QTHCHP--MDILGTCATEQSRCLRAYLGLIGTAMTPNFVSNVNTSVALS--CTCRGSGNL 324
             +C      +    A     CL +Y G+IG  MTPN+V +  T + +S  C+CRGSGN+
Sbjct: 272 HANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNM 331

Query: 325 QEECEMLEGFFSHNPCLTEAIAA 347
           +EECE     F+ NPCL  AI A
Sbjct: 332 EEECEKFLRDFTENPCLRNAIQA 354


>gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein
           [Homo sapiens]
          Length = 465

 Score =  192 bits (487), Expect = 6e-49
 Identities = 119/319 (37%), Positives = 158/319 (49%), Gaps = 18/319 (5%)

Query: 44  CLQARRKCQADPTCSAAYHHLDSCTSSISTPLPSEEPSVPAD-CLEAAQQLRNSSLIGCM 102
           C++A  +C  + +CS  Y  L  C +   T           D C  A + L+  SL  C 
Sbjct: 29  CVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYNCR 88

Query: 103 CHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYE-------DTVTSKPWKMNLSKLNML 155
           C R MK +  CL IYW+++++   GN  L+ SPYE       D     P+  ++ +    
Sbjct: 89  CKRGMKKEKNCLRIYWSMYQSLQ-GNDLLEDSPYEPVNSRLSDIFRVVPFISDVFQQVEH 147

Query: 156 KPDSDLCLKFAMLCTLNDKCDRLRKAYGEAC----SGPHCQRHVCLRQLLTFFEKAAEPH 211
            P  + CL  A  C L+D C + R AY   C    S   C R  C + L  FF+K    H
Sbjct: 148 IPKGNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAKH 207

Query: 212 AQGLLLCPCAPNDRGCGERRRNTIAPNCALPP-VAPNCLELRRLCFSDPLCRSRLVDFQT 270
           + G+L C C   D  C ERRR TI P C+      PNCL L+  C ++ +CRSRL DF T
Sbjct: 208 SYGMLFCSC--RDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFFT 265

Query: 271 HCHPMD-ILGTCATEQ-SRCLRAYLGLIGTAMTPNFVSNVNTSVALSCTCRGSGNLQEEC 328
           +C P    + +C  E  + CL AY GLIGT MTPN++ + + SVA  C C  SGN  EEC
Sbjct: 266 NCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEEC 325

Query: 329 EMLEGFFSHNPCLTEAIAA 347
                FF  N CL  AI A
Sbjct: 326 LKFLNFFKDNTCLKNAIQA 344


>gi|224282178 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score =  191 bits (485), Expect = 1e-48
 Identities = 120/320 (37%), Positives = 157/320 (49%), Gaps = 25/320 (7%)

Query: 44  CLQARRKCQADPTCSAAYHHLDSCTSSISTPLPSEEPSVPAD-CLEAAQQLRNSSLIGCM 102
           C++A  +C  + +CS  Y  L  C +   T           D C  A + L+  SL  C 
Sbjct: 29  CVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYNCR 88

Query: 103 CHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYEDTVTSKPWKMNLSKLNMLKP----- 157
           C R MK +  CL IYW+++++   GN  L+ SPYE      P    LS +  + P     
Sbjct: 89  CKRGMKKEKNCLRIYWSMYQSLQ-GNDLLEDSPYE------PVNSRLSDIFRVVPFISVE 141

Query: 158 ---DSDLCLKFAMLCTLNDKCDRLRKAYGEAC----SGPHCQRHVCLRQLLTFFEKAAEP 210
                + CL  A  C L+D C + R AY   C    S   C R  C + L  FF+K    
Sbjct: 142 HIPKGNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAK 201

Query: 211 HAQGLLLCPCAPNDRGCGERRRNTIAPNCALPP-VAPNCLELRRLCFSDPLCRSRLVDFQ 269
           H+ G+L C C   D  C ERRR TI P C+      PNCL L+  C ++ +CRSRL DF 
Sbjct: 202 HSYGMLFCSC--RDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFF 259

Query: 270 THCHPMD-ILGTCATEQ-SRCLRAYLGLIGTAMTPNFVSNVNTSVALSCTCRGSGNLQEE 327
           T+C P    + +C  E  + CL AY GLIGT MTPN++ + + SVA  C C  SGN  EE
Sbjct: 260 TNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEE 319

Query: 328 CEMLEGFFSHNPCLTEAIAA 347
           C     FF  N CL  AI A
Sbjct: 320 CLKFLNFFKDNTCLKNAIQA 339


>gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score =  191 bits (485), Expect = 1e-48
 Identities = 120/320 (37%), Positives = 157/320 (49%), Gaps = 25/320 (7%)

Query: 44  CLQARRKCQADPTCSAAYHHLDSCTSSISTPLPSEEPSVPAD-CLEAAQQLRNSSLIGCM 102
           C++A  +C  + +CS  Y  L  C +   T           D C  A + L+  SL  C 
Sbjct: 29  CVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYNCR 88

Query: 103 CHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYEDTVTSKPWKMNLSKLNMLKP----- 157
           C R MK +  CL IYW+++++   GN  L+ SPYE      P    LS +  + P     
Sbjct: 89  CKRGMKKEKNCLRIYWSMYQSLQ-GNDLLEDSPYE------PVNSRLSDIFRVVPFISVE 141

Query: 158 ---DSDLCLKFAMLCTLNDKCDRLRKAYGEAC----SGPHCQRHVCLRQLLTFFEKAAEP 210
                + CL  A  C L+D C + R AY   C    S   C R  C + L  FF+K    
Sbjct: 142 HIPKGNNCLDAAKACNLDDICKKYRSAYITPCTTSVSNDVCNRRKCHKALRQFFDKVPAK 201

Query: 211 HAQGLLLCPCAPNDRGCGERRRNTIAPNCALPP-VAPNCLELRRLCFSDPLCRSRLVDFQ 269
           H+ G+L C C   D  C ERRR TI P C+      PNCL L+  C ++ +CRSRL DF 
Sbjct: 202 HSYGMLFCSC--RDIACTERRRQTIVPVCSYEEREKPNCLNLQDSCKTNYICRSRLADFF 259

Query: 270 THCHPMD-ILGTCATEQ-SRCLRAYLGLIGTAMTPNFVSNVNTSVALSCTCRGSGNLQEE 327
           T+C P    + +C  E  + CL AY GLIGT MTPN++ + + SVA  C C  SGN  EE
Sbjct: 260 TNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPNYIDSSSLSVAPWCDCSNSGNDLEE 319

Query: 328 CEMLEGFFSHNPCLTEAIAA 347
           C     FF  N CL  AI A
Sbjct: 320 CLKFLNFFKDNTCLKNAIQA 339


>gi|11545875 GDNF family receptor alpha 4 isoform a precursor [Homo
           sapiens]
          Length = 269

 Score =  151 bits (382), Expect = 9e-37
 Identities = 86/209 (41%), Positives = 104/209 (49%), Gaps = 19/209 (9%)

Query: 162 CLKFAMLCTLNDKCDRLRKAYGEACSGPH----CQRHVCLRQLLTFFEKAAEPHAQGLLL 217
           C+  A  CT + +C RLR  Y   C G      C R  C R L  FF +        LL 
Sbjct: 26  CVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHALLF 85

Query: 218 CPCAPNDRGCGERRRNTIAPNCALP---PVAPNCLELRRLCFSDPLCRSRLVDFQTHCHP 274
           CPCA     C ERRR T  P+CA     P  P+CLE    C    +CR RL+ FQ  C P
Sbjct: 86  CPCA--GPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRPRLLAFQVSCTP 143

Query: 275 MDIL--GTCATEQSRCLRAYLGLIGTAMTPNFVSNVNTSVALSCTCRGSGNLQEECEMLE 332
                 G    + +RCLRAY GL+GTA+TPN+V NV+  VA  C C  SGN +E+CE   
Sbjct: 144 APSAPDGCLLDQGARCLRAYAGLVGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFR 203

Query: 333 GFFSHNPCLTEAIAAKMRFHSQLFSQDWP 361
           G F+ N CL  AI        Q F+  WP
Sbjct: 204 GLFTRNRCLDGAI--------QAFASGWP 224


>gi|22091448 GDNF family receptor alpha 4 isoform b precursor [Homo
           sapiens]
          Length = 299

 Score =  105 bits (262), Expect = 7e-23
 Identities = 76/239 (31%), Positives = 91/239 (38%), Gaps = 49/239 (20%)

Query: 162 CLKFAMLCTLNDKCDRLRKAYGEACSGPH----CQRHVCLRQLLTFFEKAAEPHAQGLLL 217
           C+  A  CT + +C RLR  Y   C G      C R  C R L  FF +        LL 
Sbjct: 26  CVDAAEACTADARCQRLRSEYVAQCLGRAAQGGCPRARCRRALRRFFARGPPALTHALLF 85

Query: 218 CPCAPNDRGCGERRRNTIAPNCALP---PVAPNCLELRRLCFSDPLCRSRLVDF------ 268
           CPCA     C ERRR T  P+CA     P  P+CLE    C    +CR            
Sbjct: 86  CPCA--GPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRCARAAAGPWRGW 143

Query: 269 -----------QTHCHPMDILGTCATEQSRCLRAYLG---------------LIGTAMTP 302
                           P  + G       R  R   G                 GTA+TP
Sbjct: 144 GRGLSPAHRPPAAQASPPGLSGLVHPSAQRPRRLPAGPGRPLPARLRGPRGVPAGTAVTP 203

Query: 303 NFVSNVNTSVALSCTCRGSGNLQEECEMLEGFFSHNPCLTEAIAAKMRFHSQLFSQDWP 361
           N+V NV+  VA  C C  SGN +E+CE   G F+ N CL  AI        Q F+  WP
Sbjct: 204 NYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAI--------QAFASGWP 254


>gi|148231468 GDNF family receptor alpha like [Homo sapiens]
          Length = 394

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 84/342 (24%), Positives = 133/342 (38%), Gaps = 61/342 (17%)

Query: 28  LAAGDPLPTE-SRLMNSCLQARRKCQADPT-CSAAYHHL-DSCTSSISTPLPSEEPSVPA 84
           LA G  L  E +   N+C   R +C  D   C  A+  + D+C  S        +P  P 
Sbjct: 7   LAMGLSLENEYTSQTNNCTYLREQCLRDANGCKHAWRVMEDACNDS--------DPGDPC 58

Query: 85  DCLEAAQQLRNSSLIGCMCHRRMKNQVA---CL---DIYWTVHRARSLGNYELDVSPYED 138
                  ++RNSS         +++      CL   D Y TV++   LG   ++ S   D
Sbjct: 59  -------KMRNSSYCNLSIQYLVESNFQFKECLCTDDFYCTVNKL--LGKKCINKS---D 106

Query: 139 TVTSKPWKMNLS-KLNMLKPDSDLCLKFAMLCTLNDKCDRLRKAYGEACS--GPHCQRHV 195
            V    +K NL+ + +        CL+ A  C  +  C+    +Y +ACS  G  C    
Sbjct: 107 NVKEDKFKWNLTTRSHHGFKGMWSCLEVAEACVGDVVCNAQLASYLKACSANGNPCDLKQ 166

Query: 196 CLRQLLTFFEKAAEPHAQGLLLCPCAPNDRGCGERRRNTIAPNCALPPV-APNCLELRRL 254
           C   +  F++      AQ L  C CA +D  C + +    +  CA+  V  P CL + R 
Sbjct: 167 CQAAIRFFYQNIPFNIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPPTCLSVIRS 226

Query: 255 CFSDPLCRSRLVDFQTHC---------HPMDILGTCATE------QSRCLRAYLGLIGTA 299
           C +D LCR     FQ+ C            + + T + +         C  AY+ ++GT 
Sbjct: 227 CQNDELCRRHYRTFQSKCWQRVTRKCHEDENCISTLSKQDLTCSGSDDCKAAYIDILGTV 286

Query: 300 MTPNFVSNVNTSVALSCTCRGSGNLQEE-CEMLEGFFSHNPC 340
           +             + CTCR     +E  C++ +       C
Sbjct: 287 L------------QVQCTCRTITQSEESLCKIFQHMLHRKSC 316


>gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2
           [Homo sapiens]
          Length = 364

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 36/102 (35%), Positives = 53/102 (51%), Gaps = 9/102 (8%)

Query: 44  CLQARRKCQADPTCSAAYHHLDSCTSSI--STPLPSEEPSVPADCLEAAQQLRNSSLIGC 101
           C++A   C A+  CS+ Y  L  C +    +T L ++E      C  A + L+ S L  C
Sbjct: 40  CVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKE------CQAALEVLQESPLYDC 93

Query: 102 MCHRRMKNQVACLDIYWTVHRARSLGNYELDVSPYEDTVTSK 143
            C R MK ++ CL IYW++H   + G    + SPYE  VTS+
Sbjct: 94  RCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYE-PVTSR 134


>gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2
           [Homo sapiens]
          Length = 140

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 8/90 (8%)

Query: 44  CLQARRKCQADPTCSAAYHHLDSCTSSI--STPLPSEEPSVPADCLEAAQQLRNSSLIGC 101
           C++A   C A+  CS+ Y  L  C +    +T L ++E      C  A + L+ S L  C
Sbjct: 40  CVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKE------CQAALEVLQESPLYDC 93

Query: 102 MCHRRMKNQVACLDIYWTVHRARSLGNYEL 131
            C R MK ++ CL IYW++H   +   + L
Sbjct: 94  RCKRGMKKELQCLQIYWSIHLGLTEAEFSL 123


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 38/126 (30%), Positives = 50/126 (39%), Gaps = 17/126 (13%)

Query: 228 GERRRNTIAPNCALPPVAP-NCLELRRLCFSDPLCRSRLVDFQ-----THCHPMDILG-T 280
           G  R  T AP   LPPVAP +C +    C  D +  +R V          C+P    G T
Sbjct: 748 GACRGPTFAP---LPPVAPLHCAQTPYGCCQDNITAARGVGLAGCPSACQCNPHGSYGGT 804

Query: 281 C--ATEQSRCLRAYLGLIGTAMTPNF-----VSNVNTSVALSCTCRGSGNLQEECEMLEG 333
           C  AT Q  C     GL      P F     +     S    C+C   G ++++CE + G
Sbjct: 805 CDPATGQCSCRPGVGGLRCDRCEPGFWNFRGIVTDGRSGCTPCSCDPQGAVRDDCEQMTG 864

Query: 334 FFSHNP 339
             S  P
Sbjct: 865 LCSCKP 870


>gi|169212906 PREDICTED: NPIP-like protein ENSP00000283050 isoform 3
           [Homo sapiens]
          Length = 363

 Score = 33.5 bits (75), Expect = 0.35
 Identities = 20/38 (52%), Positives = 21/38 (55%), Gaps = 5/38 (13%)

Query: 4   PLNPRPLPPVV-----LMLLLLLPPSPLPLAAGDPLPT 36
           PL P PLPP V       LL  LPPSPLP +  D L T
Sbjct: 288 PLPPSPLPPSVDDNLKECLLAPLPPSPLPPSVDDNLKT 325


>gi|4759336 Fanconi anemia, complementation group G [Homo sapiens]
          Length = 622

 Score = 33.5 bits (75), Expect = 0.35
 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 10/81 (12%)

Query: 11  PPVVLMLLLLLPPSPL--PLAAGDPLPTESRLMNSCLQARRKCQADPTCSAAYHHLD--S 66
           P  ++ + LLLPP  L  PL  G    T+  L + CLQ  R         AA H+LD  +
Sbjct: 319 PQFLIEVELLLPPPDLASPLHCGTQSQTKHILASRCLQTGR------AGDAAEHYLDLLA 372

Query: 67  CTSSISTPLPSEEPSVPADCL 87
                S P  S  PS P  C+
Sbjct: 373 LLLDSSEPRFSPPPSPPGPCM 393


>gi|33598912 activin A receptor, type IB isoform c precursor [Homo
          sapiens]
          Length = 487

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 43 SCLQARRKCQADPTCSAAYHHLDSCTSSISTPLPSEE---PSVPADCLEAAQQLRNS 96
          SCLQA   C+ D  C  +  +LD     + T +P  E      P  CL +++ LRN+
Sbjct: 38 SCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVELVPAGKPFYCL-SSEDLRNT 93


>gi|33598910 activin A receptor, type IB isoform b precursor [Homo
          sapiens]
          Length = 476

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 43 SCLQARRKCQADPTCSAAYHHLDSCTSSISTPLPSEE---PSVPADCLEAAQQLRNS 96
          SCLQA   C+ D  C  +  +LD     + T +P  E      P  CL +++ LRN+
Sbjct: 38 SCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVELVPAGKPFYCL-SSEDLRNT 93


>gi|4757720 activin A receptor, type IB isoform a precursor [Homo
          sapiens]
          Length = 505

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 43 SCLQARRKCQADPTCSAAYHHLDSCTSSISTPLPSEE---PSVPADCLEAAQQLRNS 96
          SCLQA   C+ D  C  +  +LD     + T +P  E      P  CL +++ LRN+
Sbjct: 38 SCLQANYTCETDGACMVSIFNLDGMEHHVRTCIPKVELVPAGKPFYCL-SSEDLRNT 93


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 66/256 (25%), Positives = 100/256 (39%), Gaps = 44/256 (17%)

Query: 2    VRPLNPRPLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMNSCLQARRKCQADPTCSAAY 61
            V P +P+P PPV        PPSPLP+ +  P P+    + S  Q+  + Q  P      
Sbjct: 1237 VSPGSPQPQPPVAASTP---PPSPLPICS-QPQPSTEATVPSPTQSPIRFQPAP------ 1286

Query: 62   HHLDSCTSSISTPLPSEEPSVPADCLEAA----QQLRNSSLIGCMCHRRMKNQVACLDIY 117
                + TS+   PLP +  S   D L +     + LR S L+               + +
Sbjct: 1287 ----AKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLV---------------EEF 1327

Query: 118  W--TVHRARSLGNYELDVS----PYEDTVTSKPWKMNLSKLNMLKPDSDLCLKFAMLCTL 171
            W  +    RSLG   +D S    P   T   +P  ++L   ++ K   D  L      ++
Sbjct: 1328 WMKSAEIRRSLGLTPVDRSKGPEPSFPTPAFRP--VSLKSYSVEKSPQDEGLHLLKPLSI 1385

Query: 172  NDKCDRLRKAYGEACSGPHCQRHVCLRQLLTFFEKAAE-PHAQGLLLCPCAPNDRGCGER 230
              +   L K  GE  S P   R    R+L +  E+  E   + GL L   + N +  G +
Sbjct: 1386 PKRLG-LPKPEGEPLSLP-TPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQ 1443

Query: 231  RRNTIAPNCALPPVAP 246
              NT       PP +P
Sbjct: 1444 SFNTSDSAMLTPPSSP 1459


>gi|239745496 PREDICTED: hypothetical protein XP_002343477 [Homo
           sapiens]
          Length = 218

 Score = 32.7 bits (73), Expect = 0.60
 Identities = 19/38 (50%), Positives = 21/38 (55%), Gaps = 5/38 (13%)

Query: 4   PLNPRPLPPVV-----LMLLLLLPPSPLPLAAGDPLPT 36
           PL P PLPP V       L + LPPSPLP +  D L T
Sbjct: 94  PLPPSPLPPSVDDNLKECLFVPLPPSPLPPSVDDNLKT 131



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 5/36 (13%)

Query: 4   PLNPRPLPPVV-----LMLLLLLPPSPLPLAAGDPL 34
           PL P PLPP V       L + LPPSPLP +  D L
Sbjct: 73  PLPPSPLPPSVDDNLKECLFVPLPPSPLPPSVDDNL 108


>gi|239745482 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 449

 Score = 32.7 bits (73), Expect = 0.60
 Identities = 19/38 (50%), Positives = 21/38 (55%), Gaps = 5/38 (13%)

Query: 4   PLNPRPLPPVV-----LMLLLLLPPSPLPLAAGDPLPT 36
           PL P PLPP V       L + LPPSPLP +  D L T
Sbjct: 345 PLPPSPLPPSVDDNLKECLFVPLPPSPLPPSVDDNLKT 382



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 5/36 (13%)

Query: 4   PLNPRPLPPVV-----LMLLLLLPPSPLPLAAGDPL 34
           PL P PLPP V       L + LPPSPLP +  D L
Sbjct: 324 PLPPSPLPPSVDDNLKECLFVPLPPSPLPPSVDDNL 359


>gi|239745475 PREDICTED: similar to NPIP-like protein
           ENSP00000283050 isoform 1 [Homo sapiens]
          Length = 385

 Score = 32.7 bits (73), Expect = 0.60
 Identities = 19/38 (50%), Positives = 21/38 (55%), Gaps = 5/38 (13%)

Query: 4   PLNPRPLPPVV-----LMLLLLLPPSPLPLAAGDPLPT 36
           PL P PLPP V       L + LPPSPLP +  D L T
Sbjct: 281 PLPPSPLPPSVDDNLKECLFVPLPPSPLPPSVDDNLKT 318



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 5/36 (13%)

Query: 4   PLNPRPLPPVV-----LMLLLLLPPSPLPLAAGDPL 34
           PL P PLPP V       L + LPPSPLP +  D L
Sbjct: 260 PLPPSPLPPSVDDNLKECLFVPLPPSPLPPSVDDNL 295


>gi|239745469 PREDICTED: nuclear pore complex interacting
           protein-like 1 [Homo sapiens]
          Length = 371

 Score = 32.7 bits (73), Expect = 0.60
 Identities = 19/38 (50%), Positives = 21/38 (55%), Gaps = 5/38 (13%)

Query: 4   PLNPRPLPPVV-----LMLLLLLPPSPLPLAAGDPLPT 36
           PL P PLPP V       L + LPPSPLP +  D L T
Sbjct: 267 PLPPSPLPPSVDDNLKECLFVPLPPSPLPPSVDDNLKT 304



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 5/36 (13%)

Query: 4   PLNPRPLPPVV-----LMLLLLLPPSPLPLAAGDPL 34
           PL P PLPP V       L + LPPSPLP +  D L
Sbjct: 246 PLPPSPLPPSVDDNLKECLFVPLPPSPLPPSVDDNL 281


>gi|63053517 keratin associated protein 10-5 [Homo sapiens]
          Length = 271

 Score = 32.7 bits (73), Expect = 0.60
 Identities = 26/105 (24%), Positives = 39/105 (37%), Gaps = 18/105 (17%)

Query: 184 EACSGPHCQRHVCLRQLLTFFEKAAEPHAQGLLLCPCAPNDRGCGERRRNTIAPNCALPP 243
           E+C  P C    CL  + T     + P  Q    C  +P   GC     ++  P+C  P 
Sbjct: 24  ESCCEPPCGTAPCLTLVCTPVSCVSSPCCQAA--CEPSPCQSGC----TSSCTPSCCQPA 77

Query: 244 VAPNCLELRRLCFSDPLCRSRLVDFQTHCHPMDILGTCATEQSRC 288
              +    +  C   P+C          C P+  L TC+ + S C
Sbjct: 78  CCASSPCQQACCV--PVC----------CKPVCCLPTCSKDSSSC 110


>gi|11386139 phospholipase C beta 3 [Homo sapiens]
          Length = 1234

 Score = 32.3 bits (72), Expect = 0.78
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 4/70 (5%)

Query: 18  LLLLPPSPLPLAAGDPLPTESRLMNSCL----QARRKCQADPTCSAAYHHLDSCTSSIST 73
           LL+ P    PLA G PLP+   LM   L    +  R     P  +     L+   S++S 
Sbjct: 437 LLIEPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPSAGGPDSAGRKRPLEQSNSALSE 496

Query: 74  PLPSEEPSVP 83
              + EPS P
Sbjct: 497 SSAATEPSSP 506


>gi|54607018 RYK receptor-like tyrosine kinase isoform 2 [Homo
          sapiens]
          Length = 607

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 16/35 (45%), Positives = 20/35 (57%)

Query: 9  PLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMNS 43
          P PP +L+LL LLP  P P AA  P P    L ++
Sbjct: 24 PPPPPLLLLLALLPLLPAPGAAAAPAPRPPELQSA 58


>gi|54607020 RYK receptor-like tyrosine kinase isoform 1 [Homo
          sapiens]
          Length = 610

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 16/35 (45%), Positives = 20/35 (57%)

Query: 9  PLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMNS 43
          P PP +L+LL LLP  P P AA  P P    L ++
Sbjct: 24 PPPPPLLLLLALLPLLPAPGAAAAPAPRPPELQSA 58


>gi|194097442 protein tyrosine phosphatase, receptor type, N
          polypeptide 2 isoform 3 precursor [Homo sapiens]
          Length = 986

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)

Query: 9  PLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMN--SCLQARRKCQADPTC 57
          P  P++L+LLLLLPP  LP AA   +P   +L     CL     C A   C
Sbjct: 3  PPLPLLLLLLLLLPPRVLP-AAPSSVPRGRQLPGRLGCLLEEGLCGASEAC 52


>gi|194097440 protein tyrosine phosphatase, receptor type, N
          polypeptide 2 isoform 1 precursor [Homo sapiens]
          Length = 1015

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 3/51 (5%)

Query: 9  PLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMN--SCLQARRKCQADPTC 57
          P  P++L+LLLLLPP  LP AA   +P   +L     CL     C A   C
Sbjct: 3  PPLPLLLLLLLLLPPRVLP-AAPSSVPRGRQLPGRLGCLLEEGLCGASEAC 52


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 24/86 (27%), Positives = 40/86 (46%), Gaps = 14/86 (16%)

Query: 9   PLPPVVLMLLLLLPPSPLPLAAGDPLPTESRLMNSCLQARRKCQADPTCSAAYHHLDSCT 68
           P PP+ +M      P P P  +G P P  S  +    Q +++    P  S++        
Sbjct: 471 PPPPMGMM------PPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSM------- 517

Query: 69  SSISTPLPSEEPSVPADCLEAAQQLR 94
            + STPLP ++ S+PA  +  A ++R
Sbjct: 518 -ASSTPLPWQQRSLPAAAMARAMRVR 542


>gi|187607437 hypothetical protein LOC27013 [Homo sapiens]
          Length = 410

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 17  LLLLLPPSPLPLAAGDPLPTESRLMNSCLQARRKCQADPTCSAAYHHLDSCTSSISTP 74
           LL  L P PLP    DP P    L+++C   ++  +  PTC A  H   +  +++S+P
Sbjct: 312 LLASLTPPPLP--PPDP-PAPPTLLHNCHLCQKLQRDSPTCHACLHPNRTVPTALSSP 366


>gi|13376335 hypothetical protein LOC79946 [Homo sapiens]
          Length = 257

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 2/48 (4%)

Query: 212 AQGLLLCPCAPNDRG-CGERRRNTIAPNCALP-PVAPNCLELRRLCFS 257
           A+G  LC    +  G CG R   T AP CA P   A +C   RR C S
Sbjct: 175 ARGAPLCSYRTSCAGSCGARTAPTPAPTCASPSAAASSCCRRRRACSS 222


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.136    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,988,615
Number of Sequences: 37866
Number of extensions: 900840
Number of successful extensions: 4003
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 3855
Number of HSP's gapped (non-prelim): 126
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.