Guide to the Human Genome
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Search of human proteins with 22035672

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]
         (524 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]         1065   0.0  
gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]          558   e-159
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]         558   e-159
gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]         558   e-159
gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]          558   e-159
gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]          558   e-159
gi|50301238 glutathione reductase [Homo sapiens]                      304   1e-82
gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens]   179   4e-45
gi|226437568 apoptosis-inducing factor, mitochondrion-associated...    37   0.058
gi|65787454 apoptosis-inducing factor, mitochondrion-associated,...    37   0.058
gi|21389617 apoptosis-inducing factor, mitochondrion-associated,...    37   0.058
gi|17196626 patatin-like phospholipase domain containing 3 [Homo...    36   0.098
gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial...    35   0.17 
gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial...    35   0.17 
gi|10864011 sulfide dehydrogenase like [Homo sapiens]                  33   0.49 
gi|4504897 karyopherin alpha 2 [Homo sapiens]                          32   1.1  
gi|4501867 aconitase 2, mitochondrial precursor [Homo sapiens]         32   1.9  
gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]    31   2.4  
gi|7662284 microtubule associated monoxygenase, calponin and LIM...    31   2.4  
gi|229577391 pyridine nucleotide-disulphide oxidoreductase domai...    30   4.1  
gi|116256451 amine oxidase (flavin containing) domain 1 [Homo sa...    30   4.1  
gi|62865635 squalene epoxidase [Homo sapiens]                          30   7.0  
gi|4557735 monoamine oxidase A [Homo sapiens]                          29   9.2  
gi|31542309 chondroitin sulfate synthase 1 [Homo sapiens]              29   9.2  
gi|21264341 spermine synthase [Homo sapiens]                           29   9.2  
gi|203096856 kinesin family member 7 [Homo sapiens]                    29   9.2  

>gi|22035672 thioredoxin reductase 2 precursor [Homo sapiens]
          Length = 524

 Score = 1065 bits (2754), Expect = 0.0
 Identities = 524/524 (100%), Positives = 524/524 (100%)

Query: 1   MAAMAVALRGLGGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQ 60
           MAAMAVALRGLGGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQ
Sbjct: 1   MAAMAVALRGLGGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQ 60

Query: 61  LGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQP 120
           LGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQP
Sbjct: 61  LGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQP 120

Query: 121 VPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLS 180
           VPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLS
Sbjct: 121 VPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLS 180

Query: 181 ADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGI 240
           ADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGI
Sbjct: 181 ADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGI 240

Query: 241 GLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDST 300
           GLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDST
Sbjct: 241 GLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDST 300

Query: 301 TGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDV 360
           TGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDV
Sbjct: 301 TGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDV 360

Query: 361 VEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHG 420
           VEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHG
Sbjct: 361 VEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHG 420

Query: 421 QEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALG 480
           QEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALG
Sbjct: 421 QEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALG 480

Query: 481 IKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG 524
           IKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGC G
Sbjct: 481 IKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG 524


>gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score =  558 bits (1437), Expect = e-159
 Identities = 276/489 (56%), Positives = 354/489 (72%), Gaps = 4/489 (0%)

Query: 39  DYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMH 98
           DYDL+++GGGSGGLA AKEAAQ G+KV V+D+V P+P GTRWGLGGTCVNVGCIPKKLMH
Sbjct: 12  DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMH 71

Query: 99  QAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIK 158
           QAALLG  +QD+ NYGW+V + V HDW +M EAVQNH+ SLNWG+RV L+++KV Y N  
Sbjct: 72  QAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAY 131

Query: 159 ASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESP 218
             F+  H +      GKE + SA+  +IATG RPRY   I G  EY I+SDD+F L   P
Sbjct: 132 GQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRY-LGIPGDKEYCISSDDLFSLPYCP 190

Query: 219 GKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRG 278
           GKTLVVGASYVALECAGFL GIGLD T+M+RSI LRGFDQ M++ + EHM  HG +F+R 
Sbjct: 191 GKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQ 250

Query: 279 CAPSRVRRLP---DGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTS 335
             P +V ++     G+L+V  + + + +   G ++TV+ AIGR   TR + LE  GV  +
Sbjct: 251 FVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKIN 310

Query: 336 PDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNV 395
             T KI V   E T+VP+IYAIGD++E + ELTP+AI AGRLL QRL+ GS+   DY+NV
Sbjct: 311 EKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENV 370

Query: 396 PTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLRE 455
           PTTVFTPLEYG  GLSEE+AV + G+E++EVYH+++ PLE+T+  RD ++CY K++C  +
Sbjct: 371 PTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTK 430

Query: 456 PPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGL 515
             + V+G H LGPNAGEVTQGFA  +KCG +  Q+  T+GIHP C+E    L ++KRSG 
Sbjct: 431 DNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGA 490

Query: 516 DPTVTGCUG 524
                GC G
Sbjct: 491 SILQAGCUG 499


>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
          Length = 649

 Score =  558 bits (1437), Expect = e-159
 Identities = 276/489 (56%), Positives = 354/489 (72%), Gaps = 4/489 (0%)

Query: 39  DYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMH 98
           DYDL+++GGGSGGLA AKEAAQ G+KV V+D+V P+P GTRWGLGGTCVNVGCIPKKLMH
Sbjct: 162 DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMH 221

Query: 99  QAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIK 158
           QAALLG  +QD+ NYGW+V + V HDW +M EAVQNH+ SLNWG+RV L+++KV Y N  
Sbjct: 222 QAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAY 281

Query: 159 ASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESP 218
             F+  H +      GKE + SA+  +IATG RPRY   I G  EY I+SDD+F L   P
Sbjct: 282 GQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRY-LGIPGDKEYCISSDDLFSLPYCP 340

Query: 219 GKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRG 278
           GKTLVVGASYVALECAGFL GIGLD T+M+RSI LRGFDQ M++ + EHM  HG +F+R 
Sbjct: 341 GKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQ 400

Query: 279 CAPSRVRRLP---DGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTS 335
             P +V ++     G+L+V  + + + +   G ++TV+ AIGR   TR + LE  GV  +
Sbjct: 401 FVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKIN 460

Query: 336 PDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNV 395
             T KI V   E T+VP+IYAIGD++E + ELTP+AI AGRLL QRL+ GS+   DY+NV
Sbjct: 461 EKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENV 520

Query: 396 PTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLRE 455
           PTTVFTPLEYG  GLSEE+AV + G+E++EVYH+++ PLE+T+  RD ++CY K++C  +
Sbjct: 521 PTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTK 580

Query: 456 PPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGL 515
             + V+G H LGPNAGEVTQGFA  +KCG +  Q+  T+GIHP C+E    L ++KRSG 
Sbjct: 581 DNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGA 640

Query: 516 DPTVTGCUG 524
                GC G
Sbjct: 641 SILQAGCUG 649


>gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]
          Length = 551

 Score =  558 bits (1437), Expect = e-159
 Identities = 276/489 (56%), Positives = 354/489 (72%), Gaps = 4/489 (0%)

Query: 39  DYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMH 98
           DYDL+++GGGSGGLA AKEAAQ G+KV V+D+V P+P GTRWGLGGTCVNVGCIPKKLMH
Sbjct: 64  DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMH 123

Query: 99  QAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIK 158
           QAALLG  +QD+ NYGW+V + V HDW +M EAVQNH+ SLNWG+RV L+++KV Y N  
Sbjct: 124 QAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAY 183

Query: 159 ASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESP 218
             F+  H +      GKE + SA+  +IATG RPRY   I G  EY I+SDD+F L   P
Sbjct: 184 GQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRY-LGIPGDKEYCISSDDLFSLPYCP 242

Query: 219 GKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRG 278
           GKTLVVGASYVALECAGFL GIGLD T+M+RSI LRGFDQ M++ + EHM  HG +F+R 
Sbjct: 243 GKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQ 302

Query: 279 CAPSRVRRLP---DGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTS 335
             P +V ++     G+L+V  + + + +   G ++TV+ AIGR   TR + LE  GV  +
Sbjct: 303 FVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKIN 362

Query: 336 PDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNV 395
             T KI V   E T+VP+IYAIGD++E + ELTP+AI AGRLL QRL+ GS+   DY+NV
Sbjct: 363 EKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENV 422

Query: 396 PTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLRE 455
           PTTVFTPLEYG  GLSEE+AV + G+E++EVYH+++ PLE+T+  RD ++CY K++C  +
Sbjct: 423 PTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTK 482

Query: 456 PPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGL 515
             + V+G H LGPNAGEVTQGFA  +KCG +  Q+  T+GIHP C+E    L ++KRSG 
Sbjct: 483 DNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGA 542

Query: 516 DPTVTGCUG 524
                GC G
Sbjct: 543 SILQAGCUG 551


>gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score =  558 bits (1437), Expect = e-159
 Identities = 276/489 (56%), Positives = 354/489 (72%), Gaps = 4/489 (0%)

Query: 39  DYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMH 98
           DYDL+++GGGSGGLA AKEAAQ G+KV V+D+V P+P GTRWGLGGTCVNVGCIPKKLMH
Sbjct: 12  DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMH 71

Query: 99  QAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIK 158
           QAALLG  +QD+ NYGW+V + V HDW +M EAVQNH+ SLNWG+RV L+++KV Y N  
Sbjct: 72  QAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAY 131

Query: 159 ASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESP 218
             F+  H +      GKE + SA+  +IATG RPRY   I G  EY I+SDD+F L   P
Sbjct: 132 GQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRY-LGIPGDKEYCISSDDLFSLPYCP 190

Query: 219 GKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRG 278
           GKTLVVGASYVALECAGFL GIGLD T+M+RSI LRGFDQ M++ + EHM  HG +F+R 
Sbjct: 191 GKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQ 250

Query: 279 CAPSRVRRLP---DGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTS 335
             P +V ++     G+L+V  + + + +   G ++TV+ AIGR   TR + LE  GV  +
Sbjct: 251 FVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKIN 310

Query: 336 PDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNV 395
             T KI V   E T+VP+IYAIGD++E + ELTP+AI AGRLL QRL+ GS+   DY+NV
Sbjct: 311 EKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENV 370

Query: 396 PTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLRE 455
           PTTVFTPLEYG  GLSEE+AV + G+E++EVYH+++ PLE+T+  RD ++CY K++C  +
Sbjct: 371 PTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTK 430

Query: 456 PPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGL 515
             + V+G H LGPNAGEVTQGFA  +KCG +  Q+  T+GIHP C+E    L ++KRSG 
Sbjct: 431 DNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGA 490

Query: 516 DPTVTGCUG 524
                GC G
Sbjct: 491 SILQAGCUG 499


>gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score =  558 bits (1437), Expect = e-159
 Identities = 276/489 (56%), Positives = 354/489 (72%), Gaps = 4/489 (0%)

Query: 39  DYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMH 98
           DYDL+++GGGSGGLA AKEAAQ G+KV V+D+V P+P GTRWGLGGTCVNVGCIPKKLMH
Sbjct: 12  DYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMH 71

Query: 99  QAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIK 158
           QAALLG  +QD+ NYGW+V + V HDW +M EAVQNH+ SLNWG+RV L+++KV Y N  
Sbjct: 72  QAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAY 131

Query: 159 ASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESP 218
             F+  H +      GKE + SA+  +IATG RPRY   I G  EY I+SDD+F L   P
Sbjct: 132 GQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRY-LGIPGDKEYCISSDDLFSLPYCP 190

Query: 219 GKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRG 278
           GKTLVVGASYVALECAGFL GIGLD T+M+RSI LRGFDQ M++ + EHM  HG +F+R 
Sbjct: 191 GKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQ 250

Query: 279 CAPSRVRRLP---DGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTS 335
             P +V ++     G+L+V  + + + +   G ++TV+ AIGR   TR + LE  GV  +
Sbjct: 251 FVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKIN 310

Query: 336 PDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNV 395
             T KI V   E T+VP+IYAIGD++E + ELTP+AI AGRLL QRL+ GS+   DY+NV
Sbjct: 311 EKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENV 370

Query: 396 PTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLRE 455
           PTTVFTPLEYG  GLSEE+AV + G+E++EVYH+++ PLE+T+  RD ++CY K++C  +
Sbjct: 371 PTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTK 430

Query: 456 PPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGL 515
             + V+G H LGPNAGEVTQGFA  +KCG +  Q+  T+GIHP C+E    L ++KRSG 
Sbjct: 431 DNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGA 490

Query: 516 DPTVTGCUG 524
                GC G
Sbjct: 491 SILQAGCUG 499


>gi|50301238 glutathione reductase [Homo sapiens]
          Length = 522

 Score =  304 bits (779), Expect = 1e-82
 Identities = 193/484 (39%), Positives = 277/484 (57%), Gaps = 27/484 (5%)

Query: 33  AAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCI 92
           AA     YD LV+GGGSGGLA A+ AA+LG + AVV+  +         LGGTCVNVGC+
Sbjct: 58  AAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHK---------LGGTCVNVGCV 108

Query: 93  PKKLMHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKV 152
           PKK+M   A+    + D  +YG+   +    +WR + E    +V  LN  ++  L    +
Sbjct: 109 PKKVMWNTAVHSEFMHDHADYGFPSCEG-KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHI 167

Query: 153 KYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYP--THIEGALEYGITSDD 210
           +     A+F  +        G K    +A HI+IATGG P  P  + I GA   GITSD 
Sbjct: 168 EIIRGHAAFTSDPKPTIEVSGKK---YTAPHILIATGGMPSTPHESQIPGA-SLGITSDG 223

Query: 211 IFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMR-SIPLRGFDQQMSSMVIEHMA 269
            F L+E PG++++VGA Y+A+E AG L+ +G  T++M+R    LR FD  +S+   E + 
Sbjct: 224 FFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELE 283

Query: 270 SHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTF----DTVLWAIGRVPDTRSL 325
           + G   L+      V++   G L+V+   +  G+    T     D +LWAIGRVP+T+ L
Sbjct: 284 NAGVEVLKFSQVKEVKKTLSG-LEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDL 342

Query: 326 NLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGG 385
           +L K G+ T  D   I+VD  + T+V  IYA+GDV  G+  LTP+AI AGR L  RLF  
Sbjct: 343 SLNKLGIQTD-DKGHIIVDEFQNTNVKGIYAVGDVC-GKALLTPVAIAAGRKLAHRLFEY 400

Query: 386 SSD-LMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDAS 444
             D  +DY+N+PT VF+    G VGL+E+EA+ ++G E+V+ Y   + P+   V  R  +
Sbjct: 401 KEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKR-KT 459

Query: 445 QCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEV 504
           +C +KMVC  +  + V+G+H  G    E+ QGFA+ +K GA+ A    TV IHPT SEE+
Sbjct: 460 KCVMKMVCANK-EEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 518

Query: 505 VKLR 508
           V LR
Sbjct: 519 VTLR 522


>gi|91199540 dihydrolipoamide dehydrogenase precursor [Homo sapiens]
          Length = 509

 Score =  179 bits (455), Expect = 4e-45
 Identities = 144/470 (30%), Positives = 225/470 (47%), Gaps = 24/470 (5%)

Query: 39  DYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLM- 97
           D D+ V+G G GG   A +AAQLG K   ++  E         LGGTC+NVGCIP K + 
Sbjct: 41  DADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNET--------LGGTCLNVGCIPSKALL 92

Query: 98  ---HQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKY 154
              H   +  G  +D  + G E+++ V  +  KM E     VK+L  G     +  KV +
Sbjct: 93  NNSHYYHMAHG--KDFASRGIEMSE-VRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVH 149

Query: 155 FNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWL 214
            N       ++ V      G   ++   +I+IATG        I    +  ++S     L
Sbjct: 150 VNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSL 209

Query: 215 KESPGKTLVVGASYVALECAGFLTGIGLDTTIM--MRSIPLRGFDQQMSSMVIEHMASHG 272
           K+ P K +V+GA  + +E       +G D T +  +  +   G D ++S      +   G
Sbjct: 210 KKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQG 269

Query: 273 TRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGV 332
            +F      +   +  DG++ V+ E ++ GK +  T D +L  IGR P T++L LE+ G+
Sbjct: 270 FKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGI 329

Query: 333 DTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDY 392
           +  P   +I V++R  T +P+IYAIGDVV G P L   A   G + V+ + GG+  + DY
Sbjct: 330 ELDP-RGRIPVNTRFQTKIPNIYAIGDVVAG-PMLAHKAEDEGIICVEGMAGGAVHI-DY 386

Query: 393 DNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVC 452
           + VP+ ++T  E   VG SEE+      +E +E     +     + A  +A    +  + 
Sbjct: 387 NCVPSVIYTHPEVAWVGKSEEQL----KEEGIEYKVGKFPFAANSRAKTNADTDGMVKIL 442

Query: 453 LREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSE 502
            ++    VLG H LGP AGE+    AL ++ GAS   + R    HPT SE
Sbjct: 443 GQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSE 492


>gi|226437568 apoptosis-inducing factor, mitochondrion-associated, 3
           isoform 3 [Homo sapiens]
          Length = 604

 Score = 36.6 bits (83), Expect = 0.058
 Identities = 56/244 (22%), Positives = 98/244 (40%), Gaps = 34/244 (13%)

Query: 222 LVVGASYVALECAGFLTGIGLDTTIM-MRSIPLRGF-DQQMSSMVIEHMASHGTRFLRGC 279
           +VVGA ++ +E A +LT      +++ +   P R F  +++   +++   ++  +F    
Sbjct: 342 VVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQT 401

Query: 280 APSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQ 339
             S +R       +V  + S   +      D  +  IG VP T  L     G+D+     
Sbjct: 402 EVSELRGQEGKLKEVVLKSSKVVRA-----DVCVVGIGAVPATGFLRQSGIGLDS---RG 453

Query: 340 KILVDSREATSVPHIYAIGDVV-------EGRPELTP---IAIMAGRLLVQRLFGGSSDL 389
            I V+    T+VP ++A GD V         R    P   +A   GR+  Q +    +++
Sbjct: 454 FIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEM 513

Query: 390 MDYDNVPTTVF-TPLEYGCVG-----------LSEEEAVARH--GQEHVEVYHAHYKPLE 435
                + T +F   L Y   G           L E + VA +  G E + V   +Y P+ 
Sbjct: 514 STVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIV 573

Query: 436 FTVA 439
             VA
Sbjct: 574 SKVA 577


>gi|65787454 apoptosis-inducing factor, mitochondrion-associated, 3
           isoform 2 [Homo sapiens]
          Length = 598

 Score = 36.6 bits (83), Expect = 0.058
 Identities = 56/244 (22%), Positives = 98/244 (40%), Gaps = 34/244 (13%)

Query: 222 LVVGASYVALECAGFLTGIGLDTTIM-MRSIPLRGF-DQQMSSMVIEHMASHGTRFLRGC 279
           +VVGA ++ +E A +LT      +++ +   P R F  +++   +++   ++  +F    
Sbjct: 336 VVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQT 395

Query: 280 APSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQ 339
             S +R       +V  + S   +      D  +  IG VP T  L     G+D+     
Sbjct: 396 EVSELRGQEGKLKEVVLKSSKVVRA-----DVCVVGIGAVPATGFLRQSGIGLDS---RG 447

Query: 340 KILVDSREATSVPHIYAIGDVV-------EGRPELTP---IAIMAGRLLVQRLFGGSSDL 389
            I V+    T+VP ++A GD V         R    P   +A   GR+  Q +    +++
Sbjct: 448 FIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEM 507

Query: 390 MDYDNVPTTVF-TPLEYGCVG-----------LSEEEAVARH--GQEHVEVYHAHYKPLE 435
                + T +F   L Y   G           L E + VA +  G E + V   +Y P+ 
Sbjct: 508 STVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIV 567

Query: 436 FTVA 439
             VA
Sbjct: 568 SKVA 571


>gi|21389617 apoptosis-inducing factor, mitochondrion-associated, 3
           isoform 1 [Homo sapiens]
          Length = 605

 Score = 36.6 bits (83), Expect = 0.058
 Identities = 56/244 (22%), Positives = 98/244 (40%), Gaps = 34/244 (13%)

Query: 222 LVVGASYVALECAGFLTGIGLDTTIM-MRSIPLRGF-DQQMSSMVIEHMASHGTRFLRGC 279
           +VVGA ++ +E A +LT      +++ +   P R F  +++   +++   ++  +F    
Sbjct: 336 VVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQT 395

Query: 280 APSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQ 339
             S +R       +V  + S   +      D  +  IG VP T  L     G+D+     
Sbjct: 396 EVSELRGQEGKLKEVVLKSSKVVRA-----DVCVVGIGAVPATGFLRQSGIGLDS---RG 447

Query: 340 KILVDSREATSVPHIYAIGDVV-------EGRPELTP---IAIMAGRLLVQRLFGGSSDL 389
            I V+    T+VP ++A GD V         R    P   +A   GR+  Q +    +++
Sbjct: 448 FIPVNKMMQTNVPGVFAAGDAVTFPLAWRNNRKVNIPHWQMAHAQGRVAAQNMLAQEAEM 507

Query: 390 MDYDNVPTTVF-TPLEYGCVG-----------LSEEEAVARH--GQEHVEVYHAHYKPLE 435
                + T +F   L Y   G           L E + VA +  G E + V   +Y P+ 
Sbjct: 508 STVPYLWTAMFGKSLRYAGYGEGFDDVIIQGDLEELKFVAFYTKGDEVIAVASMNYDPIV 567

Query: 436 FTVA 439
             VA
Sbjct: 568 SKVA 571


>gi|17196626 patatin-like phospholipase domain containing 3 [Homo
           sapiens]
          Length = 481

 Score = 35.8 bits (81), Expect = 0.098
 Identities = 24/78 (30%), Positives = 44/78 (56%), Gaps = 6/78 (7%)

Query: 222 LVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLR---- 277
           ++ GAS  AL C G L+GI L+ T+ + S  +R    +  ++ I H + + ++FLR    
Sbjct: 42  MLFGASAGALHCVGVLSGIPLEQTLQVLSDLVR--KARSRNIGIFHPSFNLSKFLRQGLC 99

Query: 278 GCAPSRVRRLPDGQLQVT 295
            C P+ V +L  G++ ++
Sbjct: 100 KCLPANVHQLISGKIGIS 117


>gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial
          [Homo sapiens]
          Length = 727

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 14/31 (45%), Positives = 22/31 (70%)

Query: 39 DYDLLVVGGGSGGLACAKEAAQLGRKVAVVD 69
          ++D+LV+GGG+ G  CA +A   G K A+V+
Sbjct: 69 EFDILVIGGGATGSGCALDAVTRGLKTALVE 99


>gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial
          [Homo sapiens]
          Length = 727

 Score = 35.0 bits (79), Expect = 0.17
 Identities = 14/31 (45%), Positives = 22/31 (70%)

Query: 39 DYDLLVVGGGSGGLACAKEAAQLGRKVAVVD 69
          ++D+LV+GGG+ G  CA +A   G K A+V+
Sbjct: 69 EFDILVIGGGATGSGCALDAVTRGLKTALVE 99


>gi|10864011 sulfide dehydrogenase like [Homo sapiens]
          Length = 450

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 20/42 (47%), Positives = 27/42 (64%), Gaps = 5/42 (11%)

Query: 35 AGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAV--VDYVEPS 74
          A +  Y++LV+GGGSGG+     AA++ RKV    V  VEPS
Sbjct: 39 AARNHYEVLVLGGGSGGITM---AARMKRKVGAENVAIVEPS 77


>gi|4504897 karyopherin alpha 2 [Homo sapiens]
          Length = 529

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 5/79 (6%)

Query: 304 EDTGTFDTVLWAIGRV---PDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDV 360
           +D        WAI  +   P+ R   + K GV   P   K+L  S      P + AIG++
Sbjct: 263 DDPEVLADTCWAISYLTDGPNERIGMVVKTGV--VPQLVKLLGASELPIVTPALRAIGNI 320

Query: 361 VEGRPELTPIAIMAGRLLV 379
           V G  E T + I AG L V
Sbjct: 321 VTGTDEQTQVVIDAGALAV 339


>gi|4501867 aconitase 2, mitochondrial precursor [Homo sapiens]
          Length = 780

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 12/81 (14%)

Query: 20  QAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEP------ 73
           +A  GG +   R     Q  Y+ L   G   G+   K  + +  ++ + +Y  P      
Sbjct: 131 EAQVGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWKPGSGIIHQIILENYAYPGVLLIG 190

Query: 74  ----SPQGTRWGLGGTCVNVG 90
               +P G   GLGG C+ VG
Sbjct: 191 TDSHTPNGG--GLGGICIGVG 209


>gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]
          Length = 610

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 8/50 (16%)

Query: 41  DLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVG 90
           D++V+G G GGLA A   A+ G++V V++      Q T+   GG C   G
Sbjct: 69  DVVVIGSGFGGLAAAAILAKAGKRVLVLE------QHTK--AGGCCHTFG 110


>gi|7662284 microtubule associated monoxygenase, calponin and LIM
           domain containing 2 [Homo sapiens]
          Length = 1124

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 16/27 (59%), Positives = 18/27 (66%)

Query: 43  LVVGGGSGGLACAKEAAQLGRKVAVVD 69
           L+VGGG  GL  A E A LG KV VV+
Sbjct: 90  LIVGGGPCGLRTAIELAYLGAKVVVVE 116


>gi|229577391 pyridine nucleotide-disulphide oxidoreductase domain 2
           [Homo sapiens]
          Length = 581

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 8/70 (11%)

Query: 39  DYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMH 98
           +YD +V+G G  GL  A    +LG   AV +         R  +GG  V    IP     
Sbjct: 34  EYDAVVIGAGHNGLVAAAYLQRLGVNTAVFE--------RRHVIGGAAVTEEIIPGFKFS 85

Query: 99  QAALLGGLIQ 108
           +A+ L  L++
Sbjct: 86  RASYLLSLLR 95


>gi|116256451 amine oxidase (flavin containing) domain 1 [Homo
           sapiens]
          Length = 590

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 13/67 (19%)

Query: 38  RDY---DLLVVGGGSGGLACAKEAAQLGRKVAVVD---------YVEPSPQGTRWGLGGT 85
           +DY    ++++G G  GLA A++    G KV V++         + + S +G   G G  
Sbjct: 246 KDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQ 305

Query: 86  CVNVGCI 92
            VN GCI
Sbjct: 306 IVN-GCI 311


>gi|62865635 squalene epoxidase [Homo sapiens]
          Length = 574

 Score = 29.6 bits (65), Expect = 7.0
 Identities = 15/41 (36%), Positives = 25/41 (60%)

Query: 29  AARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVD 69
           AA  + + Q D ++++VG G  G A A   ++ GRKV V++
Sbjct: 113 AACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE 153


>gi|4557735 monoamine oxidase A [Homo sapiens]
          Length = 527

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 12/30 (40%), Positives = 20/30 (66%)

Query: 40 YDLLVVGGGSGGLACAKEAAQLGRKVAVVD 69
          +D++V+GGG  GL+ AK   + G  V V++
Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGVSVLVLE 43


>gi|31542309 chondroitin sulfate synthase 1 [Homo sapiens]
          Length = 802

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 18/64 (28%)

Query: 213 WLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFD-----QQMSSMVIEH 267
           W K  PGK               F +  G DT++ +  +PLRG D     Q+ S M++++
Sbjct: 109 WSKTIPGKVQ-------------FFSSEGSDTSVPIPVVPLRGVDDSYPPQKKSFMMLKY 155

Query: 268 MASH 271
           M  H
Sbjct: 156 MHDH 159


>gi|21264341 spermine synthase [Homo sapiens]
          Length = 366

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 20/59 (33%), Positives = 33/59 (55%), Gaps = 6/59 (10%)

Query: 35  AGQRDY---DLLVVGGGSGGLACAKEAAQLGRK-VAVVDYVEPSPQGTRWGLGGTCVNV 89
           +G+ DY   D+L++GGG GG+ C  E  +L  K V +V+  +    G +  +  TC +V
Sbjct: 184 SGKEDYTGKDVLILGGGDGGILC--EIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDV 240


>gi|203096856 kinesin family member 7 [Homo sapiens]
          Length = 1343

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 16/108 (14%)

Query: 194 YPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPL 253
           Y       LE G  S DI   ++  G  ++ G   V +E        GLD  + +  + +
Sbjct: 149 YKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE--------GLDEVLSL--LEM 198

Query: 254 RGFDQQMSSMVIEHMASHG------TRFLRGCAPSRVRRLPDGQLQVT 295
               +   +  + H++S        T   RG APSR+ R   GQL V+
Sbjct: 199 GNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVS 246


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,285,002
Number of Sequences: 37866
Number of extensions: 939034
Number of successful extensions: 2086
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2042
Number of HSP's gapped (non-prelim): 30
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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