Guide to the Human Genome
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Search of human proteins with 22035657

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo
sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens]      682   0.0  
gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens]                652   0.0  
gi|22035646 apolipoprotein L3 isoform 1 [Homo sapiens]                374   e-104
gi|211938442 apolipoprotein L1 isoform c precursor [Homo sapiens]     248   6e-66
gi|13562090 apolipoprotein L2 [Homo sapiens]                          241   7e-64
gi|22035653 apolipoprotein L2 [Homo sapiens]                          241   7e-64
gi|211938440 apolipoprotein L1 isoform a precursor [Homo sapiens]     237   1e-62
gi|21735616 apolipoprotein L1 isoform b precursor [Homo sapiens]      237   1e-62
gi|21735614 apolipoprotein L1 isoform a precursor [Homo sapiens]      237   1e-62
gi|22035650 apolipoprotein L3 isoform 3 [Homo sapiens]                194   8e-50
gi|22035648 apolipoprotein L3 isoform 3 [Homo sapiens]                194   8e-50
gi|13449281 apolipoprotein L6 [Homo sapiens]                          104   1e-22
gi|13470094 apolipoprotein L5 [Homo sapiens]                          102   7e-22
gi|194353995 apolipoprotein L domain containing 1 isoform 1 [Hom...    54   3e-07
gi|194353993 apolipoprotein L domain containing 1 isoform 2 [Hom...    54   3e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    35   0.13 
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    35   0.13 
gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]          33   0.38 
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     32   1.1  
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    30   2.5  
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]    30   2.5  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    30   2.5  
gi|54792740 transmembrane and coiled-coil domain family 2 [Homo ...    30   3.2  
gi|224593756 hypothetical protein LOC164127 [Homo sapiens]             30   4.2  
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]                    30   4.2  
gi|117553617 hypothetical protein LOC440087 [Homo sapiens]             30   4.2  
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    29   5.5  
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo...    29   7.2  
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 29   7.2  
gi|32189394 mitochondrial ATP synthase beta subunit precursor [H...    29   7.2  

>gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens]
          Length = 351

 Score =  682 bits (1759), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MEGAALLKIFVVCIWVQQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDE 60
           MEGAALLKIFVVCIWVQQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDE
Sbjct: 1   MEGAALLKIFVVCIWVQQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDE 60

Query: 61  AWKRFVRVAELPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQ 120
           AWKRFVRVAELPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQ
Sbjct: 61  AWKRFVRVAELPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQ 120

Query: 121 ESIERLRVIANEIEKVHRGCVIANVVSGSTGILSVIGVMLAPFTAGLSLSITAAGVGLGI 180
           ESIERLRVIANEIEKVHRGCVIANVVSGSTGILSVIGVMLAPFTAGLSLSITAAGVGLGI
Sbjct: 121 ESIERLRVIANEIEKVHRGCVIANVVSGSTGILSVIGVMLAPFTAGLSLSITAAGVGLGI 180

Query: 181 ASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILRDITPNVLSFALDFDEAT 240
           ASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILRDITPNVLSFALDFDEAT
Sbjct: 181 ASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILRDITPNVLSFALDFDEAT 240

Query: 241 KMIANDVHTLRRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVL 300
           KMIANDVHTLRRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVL
Sbjct: 241 KMIANDVHTLRRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVL 300

Query: 301 VVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKAG 351
           VVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKAG
Sbjct: 301 VVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKAG 351


>gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens]
          Length = 348

 Score =  652 bits (1683), Expect = 0.0
 Identities = 336/341 (98%), Positives = 338/341 (99%)

Query: 11  VVCIWVQQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAE 70
           +  + VQQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAE
Sbjct: 8   ITSVGVQQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAE 67

Query: 71  LPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIA 130
           LPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIA
Sbjct: 68  LPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIA 127

Query: 131 NEIEKVHRGCVIANVVSGSTGILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASS 190
           NEIEKVHRGCVIANVVSGSTGILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASS
Sbjct: 128 NEIEKVHRGCVIANVVSGSTGILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASS 187

Query: 191 IVENTYTRSAELTASRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTL 250
           IVENTYTRSAELTASRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTL
Sbjct: 188 IVENTYTRSAELTASRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTL 247

Query: 251 RRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQ 310
           RRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQ
Sbjct: 248 RRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQ 307

Query: 311 DSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKAG 351
           DSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKAG
Sbjct: 308 DSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKAG 348


>gi|22035646 apolipoprotein L3 isoform 1 [Homo sapiens]
          Length = 402

 Score =  374 bits (961), Expect = e-104
 Identities = 195/324 (60%), Positives = 249/324 (76%), Gaps = 4/324 (1%)

Query: 29  FQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTP 88
           F EKKRFTEE  +YF+++VSPVHL+ILLT++EAWKRFV  AELPR+EADALYEALK L  
Sbjct: 73  FLEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRT 132

Query: 89  YVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSG 148
           Y AIED+ +QQK++QFREWFLKEFPQ++ KIQESIE+LR +AN IE+VHRGC I+NVVS 
Sbjct: 133 YAAIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSS 192

Query: 149 STG----ILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTA 204
           STG    I+S+ G++LAPFTAG SL++TAAGVGLG ASA  GI +SIVE++YT SAE  A
Sbjct: 193 STGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEA 252

Query: 205 SRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSKATVGRPLIAW 264
           SRLTATS D+L+  ++++RDITPN+LS   ++ EAT+ I +++  +R+++A    P+  W
Sbjct: 253 SRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTW 312

Query: 265 RYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESA 324
           R    +  +  RT    TR V + AR L   TSG+ + LDVVNLV +S  LH+GAKS SA
Sbjct: 313 RISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASA 372

Query: 325 ESLRQWAQELEENLNELTHIHQSL 348
           E LR+ AQELEENL ELT I+Q L
Sbjct: 373 EELRRQAQELEENLMELTQIYQRL 396


>gi|211938442 apolipoprotein L1 isoform c precursor [Homo sapiens]
          Length = 380

 Score =  248 bits (633), Expect = 6e-66
 Identities = 154/379 (40%), Positives = 224/379 (59%), Gaps = 32/379 (8%)

Query: 1   MEGAALLKIFVVCIWVQQNHPGWTVAGQFQEKKR--------------FTEEVIEYFQKK 46
           MEGAALL++ V+CIWVQQN P  T  G  Q K                F E+ I+YF++K
Sbjct: 1   MEGAALLRVSVLCIWVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEK 60

Query: 47  VSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTPYVAIEDKDMQQKEQQFRE 106
           VS  +L +LLT +EAW  FV  AELPR EAD L +AL NL   + ++DK+   K QQ+R 
Sbjct: 61  VSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRN 120

Query: 107 WFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSG----STGILSVIGVMLAP 162
           WFLKEFP+++ +++++I RLR +A+ ++KVH+G  IANVVSG    S+GIL+++G+ LAP
Sbjct: 121 WFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAP 180

Query: 163 FTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDIL 222
           FT G SL +   G+ LGI +A  GI SS ++       +  A  L   S D+L+ +R+ L
Sbjct: 181 FTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFL 240

Query: 223 RDITPNVLSFALDFDEATKMIANDVHTLRRSK--------ATVGRPLIAWRYVPINVVET 274
            +   N LS A +  + T+ I  D+  LRR++        A+  RP +     PI+    
Sbjct: 241 GENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVT---EPISAESG 297

Query: 275 LRTRGAPTRIVRKVARNL---GKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWA 331
            +        + +++R +     A     +VLDVV LV +S  LH+GAKSE+AE L++ A
Sbjct: 298 EQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVA 357

Query: 332 QELEENLNELTHIHQSLKA 350
           QELEE LN L + ++ L+A
Sbjct: 358 QELEEKLNILNNNYKILQA 376


>gi|13562090 apolipoprotein L2 [Homo sapiens]
          Length = 337

 Score =  241 bits (615), Expect = 7e-64
 Identities = 135/334 (40%), Positives = 206/334 (61%), Gaps = 16/334 (4%)

Query: 31  EKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTPYV 90
           E   F E+ ++YFQ +VS  +L  LLT DEAW  FV  AELPR+EAD L +AL  L  ++
Sbjct: 4   ESSIFIEDYLKYFQDQVSRENLLQLLTDDEAWNGFVAAAELPRDEADELRKALNKLASHM 63

Query: 91  AIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSGS- 149
            ++DK+   K+QQ R+WFLKEFP+++ ++++ I +LR +A E+E+VHRG  IANVVS S 
Sbjct: 64  VMKDKNRHDKDQQHRQWFLKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSV 123

Query: 150 ---TGILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASR 206
              +GIL+++G+ LAPFT G+S  +   G+GLG A+A AGI  S+VE      A   A  
Sbjct: 124 GTTSGILTLLGLGLAPFTEGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARN 183

Query: 207 LTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSKATVGRPLIAWRY 266
           L  + T+  + +++ +   TPNVL+   ++ + T+ I  ++  +RR++A    P +    
Sbjct: 184 LDQSGTNVAKVMKEFVGGNTPNVLTLVDNWYQVTQGIGRNIRAIRRARA---NPQLGAYA 240

Query: 267 VPINVVETLRTRG---------APTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHK 317
            P +++  +   G          P + + +    +G AT G+L++LDVV+L  +S  L +
Sbjct: 241 PPPHIIGRISAEGGEQVERVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLE 300

Query: 318 GAKSESAESLRQWAQELEENLNELTHIHQSLKAG 351
           GAKSESAE L++ AQELE  LN LT IH+ L+ G
Sbjct: 301 GAKSESAEELKKRAQELEGKLNFLTKIHEMLQPG 334


>gi|22035653 apolipoprotein L2 [Homo sapiens]
          Length = 337

 Score =  241 bits (615), Expect = 7e-64
 Identities = 135/334 (40%), Positives = 206/334 (61%), Gaps = 16/334 (4%)

Query: 31  EKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTPYV 90
           E   F E+ ++YFQ +VS  +L  LLT DEAW  FV  AELPR+EAD L +AL  L  ++
Sbjct: 4   ESSIFIEDYLKYFQDQVSRENLLQLLTDDEAWNGFVAAAELPRDEADELRKALNKLASHM 63

Query: 91  AIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSGS- 149
            ++DK+   K+QQ R+WFLKEFP+++ ++++ I +LR +A E+E+VHRG  IANVVS S 
Sbjct: 64  VMKDKNRHDKDQQHRQWFLKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSV 123

Query: 150 ---TGILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASR 206
              +GIL+++G+ LAPFT G+S  +   G+GLG A+A AGI  S+VE      A   A  
Sbjct: 124 GTTSGILTLLGLGLAPFTEGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARN 183

Query: 207 LTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSKATVGRPLIAWRY 266
           L  + T+  + +++ +   TPNVL+   ++ + T+ I  ++  +RR++A    P +    
Sbjct: 184 LDQSGTNVAKVMKEFVGGNTPNVLTLVDNWYQVTQGIGRNIRAIRRARA---NPQLGAYA 240

Query: 267 VPINVVETLRTRG---------APTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHK 317
            P +++  +   G          P + + +    +G AT G+L++LDVV+L  +S  L +
Sbjct: 241 PPPHIIGRISAEGGEQVERVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLE 300

Query: 318 GAKSESAESLRQWAQELEENLNELTHIHQSLKAG 351
           GAKSESAE L++ AQELE  LN LT IH+ L+ G
Sbjct: 301 GAKSESAEELKKRAQELEGKLNFLTKIHEMLQPG 334


>gi|211938440 apolipoprotein L1 isoform a precursor [Homo sapiens]
          Length = 398

 Score =  237 bits (604), Expect = 1e-62
 Identities = 154/397 (38%), Positives = 224/397 (56%), Gaps = 50/397 (12%)

Query: 1   MEGAALLKIFVVCIW------------------VQQNHPGWTVAGQFQEKKR-------- 34
           MEGAALL++ V+CIW                  VQQN P  T  G  Q K          
Sbjct: 1   MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTM 60

Query: 35  ------FTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTP 88
                 F E+ I+YF++KVS  +L +LLT +EAW  FV  AELPR EAD L +AL NL  
Sbjct: 61  DPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLAR 120

Query: 89  YVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSG 148
            + ++DK+   K QQ+R WFLKEFP+++ +++++I RLR +A+ ++KVH+G  IANVVSG
Sbjct: 121 QMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSG 180

Query: 149 ----STGILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTA 204
               S+GIL+++G+ LAPFT G SL +   G+ LGI +A  GI SS ++       +  A
Sbjct: 181 SLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQA 240

Query: 205 SRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSK--------AT 256
             L   S D+L+ +R+ L +   N LS A +  + T+ I  D+  LRR++        A+
Sbjct: 241 HDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHAS 300

Query: 257 VGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNL---GKATSGVLVVLDVVNLVQDSL 313
             RP +     PI+     +        + +++R +     A     +VLDVV LV +S 
Sbjct: 301 ASRPRVT---EPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESK 357

Query: 314 DLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKA 350
            LH+GAKSE+AE L++ AQELEE LN L + ++ L+A
Sbjct: 358 HLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQA 394


>gi|21735616 apolipoprotein L1 isoform b precursor [Homo sapiens]
          Length = 414

 Score =  237 bits (604), Expect = 1e-62
 Identities = 154/397 (38%), Positives = 224/397 (56%), Gaps = 50/397 (12%)

Query: 1   MEGAALLKIFVVCIW------------------VQQNHPGWTVAGQFQEKKR-------- 34
           MEGAALL++ V+CIW                  VQQN P  T  G  Q K          
Sbjct: 17  MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTM 76

Query: 35  ------FTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTP 88
                 F E+ I+YF++KVS  +L +LLT +EAW  FV  AELPR EAD L +AL NL  
Sbjct: 77  DPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLAR 136

Query: 89  YVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSG 148
            + ++DK+   K QQ+R WFLKEFP+++ +++++I RLR +A+ ++KVH+G  IANVVSG
Sbjct: 137 QMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSG 196

Query: 149 ----STGILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTA 204
               S+GIL+++G+ LAPFT G SL +   G+ LGI +A  GI SS ++       +  A
Sbjct: 197 SLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQA 256

Query: 205 SRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSK--------AT 256
             L   S D+L+ +R+ L +   N LS A +  + T+ I  D+  LRR++        A+
Sbjct: 257 HDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHAS 316

Query: 257 VGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNL---GKATSGVLVVLDVVNLVQDSL 313
             RP +     PI+     +        + +++R +     A     +VLDVV LV +S 
Sbjct: 317 ASRPRVT---EPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESK 373

Query: 314 DLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKA 350
            LH+GAKSE+AE L++ AQELEE LN L + ++ L+A
Sbjct: 374 HLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQA 410


>gi|21735614 apolipoprotein L1 isoform a precursor [Homo sapiens]
          Length = 398

 Score =  237 bits (604), Expect = 1e-62
 Identities = 154/397 (38%), Positives = 224/397 (56%), Gaps = 50/397 (12%)

Query: 1   MEGAALLKIFVVCIW------------------VQQNHPGWTVAGQFQEKKR-------- 34
           MEGAALL++ V+CIW                  VQQN P  T  G  Q K          
Sbjct: 1   MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTM 60

Query: 35  ------FTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTP 88
                 F E+ I+YF++KVS  +L +LLT +EAW  FV  AELPR EAD L +AL NL  
Sbjct: 61  DPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLAR 120

Query: 89  YVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSG 148
            + ++DK+   K QQ+R WFLKEFP+++ +++++I RLR +A+ ++KVH+G  IANVVSG
Sbjct: 121 QMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSG 180

Query: 149 ----STGILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTA 204
               S+GIL+++G+ LAPFT G SL +   G+ LGI +A  GI SS ++       +  A
Sbjct: 181 SLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQA 240

Query: 205 SRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSK--------AT 256
             L   S D+L+ +R+ L +   N LS A +  + T+ I  D+  LRR++        A+
Sbjct: 241 HDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHAS 300

Query: 257 VGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNL---GKATSGVLVVLDVVNLVQDSL 313
             RP +     PI+     +        + +++R +     A     +VLDVV LV +S 
Sbjct: 301 ASRPRVT---EPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESK 357

Query: 314 DLHKGAKSESAESLRQWAQELEENLNELTHIHQSLKA 350
            LH+GAKSE+AE L++ AQELEE LN L + ++ L+A
Sbjct: 358 HLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQA 394


>gi|22035650 apolipoprotein L3 isoform 3 [Homo sapiens]
          Length = 202

 Score =  194 bits (494), Expect = 8e-50
 Identities = 104/196 (53%), Positives = 140/196 (71%)

Query: 153 LSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTATST 212
           +S+ G++LAPFTAG SL++TAAGVGLG ASA  GI +SIVE++YT SAE  ASRLTATS 
Sbjct: 1   MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 60

Query: 213 DQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSKATVGRPLIAWRYVPINVV 272
           D+L+  ++++RDITPN+LS   ++ EAT+ I +++  +R+++A    P+  WR    +  
Sbjct: 61  DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGG 120

Query: 273 ETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQ 332
           +  RT    TR V + AR L   TSG+ + LDVVNLV +S  LH+GAKS SAE LR+ AQ
Sbjct: 121 QAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQ 180

Query: 333 ELEENLNELTHIHQSL 348
           ELEENL ELT I+Q L
Sbjct: 181 ELEENLMELTQIYQRL 196


>gi|22035648 apolipoprotein L3 isoform 3 [Homo sapiens]
          Length = 202

 Score =  194 bits (494), Expect = 8e-50
 Identities = 104/196 (53%), Positives = 140/196 (71%)

Query: 153 LSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTATST 212
           +S+ G++LAPFTAG SL++TAAGVGLG ASA  GI +SIVE++YT SAE  ASRLTATS 
Sbjct: 1   MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 60

Query: 213 DQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSKATVGRPLIAWRYVPINVV 272
           D+L+  ++++RDITPN+LS   ++ EAT+ I +++  +R+++A    P+  WR    +  
Sbjct: 61  DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGG 120

Query: 273 ETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQ 332
           +  RT    TR V + AR L   TSG+ + LDVVNLV +S  LH+GAKS SAE LR+ AQ
Sbjct: 121 QAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQ 180

Query: 333 ELEENLNELTHIHQSL 348
           ELEENL ELT I+Q L
Sbjct: 181 ELEENLMELTQIYQRL 196


>gi|13449281 apolipoprotein L6 [Homo sapiens]
          Length = 343

 Score =  104 bits (259), Expect = 1e-22
 Identities = 90/295 (30%), Positives = 149/295 (50%), Gaps = 32/295 (10%)

Query: 71  LPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIA 130
           L R+E DA       L   V ++D D+  +E+ F    L+EFP+++  ++ +I++LR +A
Sbjct: 15  LQRDEDDA------PLCEDVELQDGDLSPEEKIF----LREFPRLKEDLKGNIDKLRALA 64

Query: 131 NEIEKVHRGCVIANVVSGST----GILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAG 186
           ++I+K H+    AN+V+ ST    G++S++G+ LAP T G SL ++ AG GL  A+    
Sbjct: 65  DDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLSTAGQGLATAAGVTS 124

Query: 187 IASSIVENTYTRSAELTASRLTAT-----------STDQLEALRDILRDITPNVLSFALD 235
           I S  +E +  + A+  A  +  T             D + A   I+ ++  N L +A  
Sbjct: 125 IVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKIIYNLR-NTLKYAKK 183

Query: 236 FDEA-TKMIANDVHTLRRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGK 294
              A  K+ AN     R + AT  R L   +    + V+  +     T  + K AR LG 
Sbjct: 184 NVRAFWKLRANP----RLANAT-KRLLTTGQVSSRSRVQVQKAFAGTTLAMTKNARVLGG 238

Query: 295 ATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNELTHIHQSLK 349
             S   +  D+  L ++   L +GA+++ AE LR  A ELE  L ELT +++SL+
Sbjct: 239 VMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYKSLQ 293


>gi|13470094 apolipoprotein L5 [Homo sapiens]
          Length = 433

 Score =  102 bits (253), Expect = 7e-22
 Identities = 73/253 (28%), Positives = 134/253 (52%), Gaps = 16/253 (6%)

Query: 108 FLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSGSTG----ILSVIGVMLAPF 163
           FL  FP  +++++++I+ L  +A++++  H      ++V+ S+G    +++++G+ LAP 
Sbjct: 102 FLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPV 161

Query: 164 TAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTATSTDQLEALRDILR 223
           TAG SL ++A G GLG A+A   I ++++EN    +A   ASRL   +T   EA   I  
Sbjct: 162 TAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSH-EAFGGI-- 218

Query: 224 DITPNVLSFALDFDEATKMI--ANDVHTLRRSKATVG-----RPLIAWRYVPINVVETL- 275
                + +     ++  K I    D+H  + +K+  G     +  +A R++P      + 
Sbjct: 219 -NWSEIEAAGFCVNKCVKAIQGIKDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQ 277

Query: 276 RTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELE 335
           R     T  +   A  +G A +G L++ D+ + +Q    L  GA++E+AE LR  A++LE
Sbjct: 278 RAFEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLE 337

Query: 336 ENLNELTHIHQSL 348
           + L+ LT  H+ L
Sbjct: 338 QELDRLTQHHRHL 350


>gi|194353995 apolipoprotein L domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 279

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 35/112 (31%), Positives = 58/112 (51%), Gaps = 6/112 (5%)

Query: 116 RWKIQESIERLRVIANEIEKVHRGCVIANVVSGS---TGIL-SVIGVMLAPFTAGLSLSI 171
           R ++   + RLR +A  +E++ R  ++ANV   S   TG L +++G+ L+P T G SL +
Sbjct: 59  RGRLHGQVLRLREVARRLERLRRRSLVANVAGSSLSATGALAAIVGLSLSPVTLGTSLLV 118

Query: 172 TAAGVGLGIASATAGIASSIVENTYTRSAEL-TASRLTATSTDQLEALRDIL 222
           +A G+G+  A     I S +    +  S EL     + AT  DQ+  +   L
Sbjct: 119 SAVGLGVATAGGAVTITSDL-SLIFCNSRELRRVQEIAATCQDQMREILSCL 169


>gi|194353993 apolipoprotein L domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 248

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 35/112 (31%), Positives = 58/112 (51%), Gaps = 6/112 (5%)

Query: 116 RWKIQESIERLRVIANEIEKVHRGCVIANVVSGS---TGIL-SVIGVMLAPFTAGLSLSI 171
           R ++   + RLR +A  +E++ R  ++ANV   S   TG L +++G+ L+P T G SL +
Sbjct: 28  RGRLHGQVLRLREVARRLERLRRRSLVANVAGSSLSATGALAAIVGLSLSPVTLGTSLLV 87

Query: 172 TAAGVGLGIASATAGIASSIVENTYTRSAEL-TASRLTATSTDQLEALRDIL 222
           +A G+G+  A     I S +    +  S EL     + AT  DQ+  +   L
Sbjct: 88  SAVGLGVATAGGAVTITSDL-SLIFCNSRELRRVQEIAATCQDQMREILSCL 138


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 27/124 (21%), Positives = 61/124 (49%), Gaps = 3/124 (2%)

Query: 17  QQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEA 76
           +Q    W    + +E++   +E +   +KK+     KI    +E W++  ++ EL     
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444

Query: 77  DALYEALKNLTPYVAIEDKDMQQKEQ--QFREWFLKEFPQIRWKIQESIERLRVIANEIE 134
           D   E L+ +   +  E++ MQ++E+  Q +E  ++E  +  W+ ++ +++   I  + E
Sbjct: 445 DQ-EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503

Query: 135 KVHR 138
           K+ R
Sbjct: 504 KMWR 507



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 26/110 (23%), Positives = 57/110 (51%), Gaps = 9/110 (8%)

Query: 23  WTVAGQFQEKKRFT-EEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELP---REEADA 78
           W +  Q QE+K +  EE I+  ++K+    LKI    ++ W++  ++ E     RE+ D 
Sbjct: 288 WNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347

Query: 79  LY---EALKNLTPYVAIEDKDMQQKEQQFREW--FLKEFPQIRWKIQESI 123
           ++   E ++     +  +++ M ++E++ RE    ++E  +  W+ +E I
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 20/106 (18%), Positives = 54/106 (50%), Gaps = 5/106 (4%)

Query: 30  QEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTPY 89
           +EK R  EE +   ++K+     KI    +E W++  ++ E   +  + ++   K +   
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ 418

Query: 90  VAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEK 135
              ++K  +Q+E+ +R+   ++  ++   +Q+  E+LR +  ++++
Sbjct: 419 ---DEKIREQEEEMWRQ--EEKIRELEEMMQDQEEKLREVEEKMQE 459


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 27/124 (21%), Positives = 61/124 (49%), Gaps = 3/124 (2%)

Query: 17  QQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEA 76
           +Q    W    + +E++   +E +   +KK+     KI    +E W++  ++ EL     
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444

Query: 77  DALYEALKNLTPYVAIEDKDMQQKEQ--QFREWFLKEFPQIRWKIQESIERLRVIANEIE 134
           D   E L+ +   +  E++ MQ++E+  Q +E  ++E  +  W+ ++ +++   I  + E
Sbjct: 445 DQ-EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503

Query: 135 KVHR 138
           K+ R
Sbjct: 504 KMWR 507



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 26/110 (23%), Positives = 57/110 (51%), Gaps = 9/110 (8%)

Query: 23  WTVAGQFQEKKRFT-EEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELP---REEADA 78
           W +  Q QE+K +  EE I+  ++K+    LKI    ++ W++  ++ E     RE+ D 
Sbjct: 288 WNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDK 347

Query: 79  LY---EALKNLTPYVAIEDKDMQQKEQQFREW--FLKEFPQIRWKIQESI 123
           ++   E ++     +  +++ M ++E++ RE    ++E  +  W+ +E I
Sbjct: 348 MWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI 397



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 20/106 (18%), Positives = 54/106 (50%), Gaps = 5/106 (4%)

Query: 30  QEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTPY 89
           +EK R  EE +   ++K+     KI    +E W++  ++ E   +  + ++   K +   
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ 418

Query: 90  VAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEK 135
              ++K  +Q+E+ +R+   ++  ++   +Q+  E+LR +  ++++
Sbjct: 419 ---DEKIREQEEEMWRQ--EEKIRELEEMMQDQEEKLREVEEKMQE 459


>gi|111955084 5-azacytidine induced 1 isoform a [Homo sapiens]
          Length = 1080

 Score = 33.1 bits (74), Expect = 0.38
 Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 15/94 (15%)

Query: 45  KKVSPVHLKILLTSDE-AWKRFVRVAELPREEADALYEALKNLTPYVAIEDKDMQQKEQQ 103
           +++  +H   LL SDE A +R +R AE  RE+ +   EAL              QQ+ ++
Sbjct: 724 RRLKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALG-------------QQERER 770

Query: 104 FREWFLKEFPQIRWKIQESIERL-RVIANEIEKV 136
            R+ F +   Q +W +Q+  +RL   +A E E++
Sbjct: 771 ARQRFQQHLEQEQWALQQQRQRLYSEVAEERERL 804


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 12/117 (10%)

Query: 17   QQNHPGWTVAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEA 76
            QQN     + G+ ++ K   E+     + ++     +I+   D   ++ +        E 
Sbjct: 1490 QQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTI--------EI 1541

Query: 77   DALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEI 133
            ++L E LKN      IE K++ QK Q F+E  L E    R  ++E+ E++  + N++
Sbjct: 1542 ESLNEVLKNYNQQKDIEHKELVQKLQHFQE--LGEEKDNR--VKEAEEKILTLENQV 1594


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 24/98 (24%), Positives = 51/98 (52%), Gaps = 8/98 (8%)

Query: 28  QFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRV---AELPREEADALYEALK 84
           Q QEK R  EE I   ++K+     KI    ++ W++  ++    E+ +E+ + ++E  +
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620

Query: 85  NLTPYVAIEDKDMQQKEQQFREWFLKEFPQ-IRWKIQE 121
            +      +++ MQ++E++ R    K + Q +R + QE
Sbjct: 621 KMCE----QEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 16/116 (13%)

Query: 23  WTVAGQFQEKKRFT-EEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYE 81
           W    Q QE+K +  EE I+ +++K+     KI     E  ++     E  R + + ++E
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIR----EQEEKIREQEEKMRRQEEMMWE 346

Query: 82  ALKNLTPYVAIEDKDMQQKEQQF-REWFLKEFPQIRWKIQESIERLRVIANEIEKV 136
                      E+K  +Q+E  + +E  ++   ++ W+ +E I  L    +E EK+
Sbjct: 347 K----------EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKI 392


>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
          Length = 862

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 250 LRRSKATVGRPLIAWRYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNL- 308
           ++  KA+V R  + WR   + ++  LR R + +R+   V     K    +L +       
Sbjct: 232 IKFQKASVSRCTLYWRDEGLVLLNRLRYRPSNSRLWNMVNVTKAKGRHDLLDLKPFTEYE 291

Query: 309 --VQDSLDLHKGAKSESAESLRQWAQELE 335
             +   L L+KG+ S+ +ESLR    E E
Sbjct: 292 FQISSKLHLYKGSWSDWSESLRAQTPEEE 320


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 30.4 bits (67), Expect = 2.5
 Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 14/120 (11%)

Query: 28   QFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLT 87
            ++QEK +  ++  E   +    V       S+EA +R   V E  R+E   LY  L++  
Sbjct: 1603 EWQEKHKELQKEYEILLQSYENV-------SNEA-ERIQHVVEAVRQEKQELYGKLRSTE 1654

Query: 88   PYVAIEDKDMQQKEQQFREW------FLKEFPQIRWKIQESIERLRVIANEIEKVHRGCV 141
                  +K +Q+ EQ+  E       F K   Q   +++E  +RLR   +      + C+
Sbjct: 1655 ANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECM 1714


>gi|54792740 transmembrane and coiled-coil domain family 2 [Homo
           sapiens]
          Length = 709

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 68/314 (21%), Positives = 124/314 (39%), Gaps = 37/314 (11%)

Query: 47  VSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTPYVAIEDKDMQQKEQQFRE 106
           +  +H KIL  +++     +++ +  R++  A Y  L N        DK    + +Q  E
Sbjct: 289 IDHLHQKILKITEQ-----IKIEQEARDDNVAEYLKLANNA------DKQQVSRIKQVFE 337

Query: 107 WFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSGSTGILSVIGVMLAPFTAG 166
              ++  Q   ++ + +E  R    EIE+        +V+      L  +G   A   AG
Sbjct: 338 KKNQKSAQTIAQLHKKLEHYRRRLKEIEQNGPSRQPKDVLRDMQQGLKDVG---ANVRAG 394

Query: 167 LSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTASRLTAT-------STDQLEALR 219
           +S      G G G+     G  S + + T+T  A ++  R  A+       S D +  L+
Sbjct: 395 IS------GFGGGVVEGVKGSLSGLSQATHT--AVVSKPREFASLIRNKFGSADNIAHLK 446

Query: 220 DILRDITPNVLSFALDFDEATKMIA------NDVHTLRRSKATVGRPLIAWRYVPINVVE 273
           D L D  P   + AL    AT + +      ++  +   S A  G    A     +   +
Sbjct: 447 DPLEDGPPEEAARALS-GSATLVSSPKYGSDDECSSASASSAGAGSNSGAGPGGALGSPK 505

Query: 274 TLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQE 333
           +    GAP  +   +   L +   G   + D +  ++  L       ++  +  R   + 
Sbjct: 506 SNALYGAPGNL-DALLEELREIKEGQSHLEDSMEDLKTQLQRDYTYMTQCLQEERYRYER 564

Query: 334 LEENLNELTHIHQS 347
           LEE LN+LT +HQ+
Sbjct: 565 LEEQLNDLTELHQN 578


>gi|224593756 hypothetical protein LOC164127 [Homo sapiens]
          Length = 623

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 17/55 (30%), Positives = 27/55 (49%)

Query: 286 RKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESAESLRQWAQELEENLNE 340
           RKV  +       +L  L +    Q S ++H+G + E    LR+ AQ+ EE L +
Sbjct: 433 RKVLMDCQAKAEELLRQLSLEQSFQRSQEIHQGLRKERQRELREKAQKEEEQLQQ 487


>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
          Length = 284

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 28/124 (22%), Positives = 58/124 (46%), Gaps = 5/124 (4%)

Query: 30  QEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTPY 89
           QEK   TE+     +  V+ ++ +I L  +E  +   R+A   ++  +A   A ++    
Sbjct: 68  QEKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGM 127

Query: 90  VAIEDKDMQQKEQ-QFREWFLKEFPQIR----WKIQESIERLRVIANEIEKVHRGCVIAN 144
             IE++ M+ +E+ + +E  LKE   I      K +E   +L ++  E+E+      ++ 
Sbjct: 128 KVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSE 187

Query: 145 VVSG 148
           +  G
Sbjct: 188 LKCG 191


>gi|117553617 hypothetical protein LOC440087 [Homo sapiens]
          Length = 225

 Score = 29.6 bits (65), Expect = 4.2
 Identities = 42/178 (23%), Positives = 76/178 (42%), Gaps = 17/178 (9%)

Query: 25  VAGQFQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALK 84
           ++  F    + TE +  +   +++ + +K   T  E     ++     ++E   + EALK
Sbjct: 29  LSDSFDVTNKLTEVLNMHLGCRLASIEMKRDGTIKENCDLIIQAIMKIQKELQKVDEALK 88

Query: 85  N-LTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIA 143
           + L P +  + +D+++KE                KI    + + VI  E         + 
Sbjct: 89  DKLEPTLYRKLQDIKEKETD--------------KIAIVQKVISVILGEATSAASAVAVK 134

Query: 144 NVVSG-STGILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSA 200
            V S  +TGI++ +  +LA   A L  SI  A +GLGI      I  + VE T  ++A
Sbjct: 135 LVGSNVTTGIINKLVTVLAQIGASLLGSIGVAVLGLGIDMIVRAILGA-VEKTQLQAA 191


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 24/110 (21%), Positives = 53/110 (48%), Gaps = 6/110 (5%)

Query: 30  QEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTPY 89
           QEKK + +E   + Q+K+     +     +E W++  ++ E  +EE     E +      
Sbjct: 449 QEKKMWRQEEKIHEQEKIREEEKR--QEQEEMWRQEEKIHE--QEEIWRQKEKMHEQEEK 504

Query: 90  VAIEDKDMQQKEQQFREWF--LKEFPQIRWKIQESIERLRVIANEIEKVH 137
           +  +++ + ++E++ RE    ++E  +  W+ +E I     +  E EK+H
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554


>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
          sapiens]
          Length = 1483

 Score = 28.9 bits (63), Expect = 7.2
 Identities = 15/28 (53%), Positives = 17/28 (60%)

Query: 56 LTSDEAWKRFVRVAELPREEADALYEAL 83
          LT  EAW+    VAEL +EE  A YE L
Sbjct: 60 LTHKEAWEEEQEVAELLKEEFPAWYEKL 87


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 28.9 bits (63), Expect = 7.2
 Identities = 19/73 (26%), Positives = 44/73 (60%), Gaps = 3/73 (4%)

Query: 63   KRFVRVAELPREEADALYEALKNLTPYVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQES 122
            K F+R+AE+ +  A+   ++L +L   +    +D++ ++++  E  +KEF  I+ ++QE+
Sbjct: 1618 KHFIRLAEMEQTVAEQ-DDSLSSLLVKLKKVSQDLE-RQREITELKVKEFENIKLQLQEN 1675

Query: 123  IE-RLRVIANEIE 134
             E  ++ +  E+E
Sbjct: 1676 HEDEVKKVKAEVE 1688


>gi|32189394 mitochondrial ATP synthase beta subunit precursor [Homo
           sapiens]
          Length = 529

 Score = 28.9 bits (63), Expect = 7.2
 Identities = 15/49 (30%), Positives = 27/49 (55%)

Query: 271 VVETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGA 319
           ++  L  +G  TR+V +VA++LG++T   + +     LV+    L  GA
Sbjct: 82  ILNALEVQGRETRLVLEVAQHLGESTVRTIAMDGTEGLVRGQKVLDSGA 130


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,084,808
Number of Sequences: 37866
Number of extensions: 434201
Number of successful extensions: 1904
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1840
Number of HSP's gapped (non-prelim): 48
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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