Guide to the Human Genome
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Search of human proteins with 22035646

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035646 apolipoprotein L3 isoform 1 [Homo sapiens]
         (402 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035646 apolipoprotein L3 isoform 1 [Homo sapiens]                785   0.0  
gi|22035650 apolipoprotein L3 isoform 3 [Homo sapiens]                384   e-106
gi|22035648 apolipoprotein L3 isoform 3 [Homo sapiens]                384   e-106
gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens]                374   e-104
gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens]      374   e-104
gi|13562090 apolipoprotein L2 [Homo sapiens]                          317   2e-86
gi|22035653 apolipoprotein L2 [Homo sapiens]                          317   2e-86
gi|211938442 apolipoprotein L1 isoform c precursor [Homo sapiens]     283   1e-76
gi|211938440 apolipoprotein L1 isoform a precursor [Homo sapiens]     283   1e-76
gi|21735616 apolipoprotein L1 isoform b precursor [Homo sapiens]      283   1e-76
gi|21735614 apolipoprotein L1 isoform a precursor [Homo sapiens]      283   1e-76
gi|13449281 apolipoprotein L6 [Homo sapiens]                          167   1e-41
gi|13470094 apolipoprotein L5 [Homo sapiens]                          135   7e-32
gi|194353995 apolipoprotein L domain containing 1 isoform 1 [Hom...    55   9e-08
gi|194353993 apolipoprotein L domain containing 1 isoform 2 [Hom...    55   9e-08
gi|91982772 mucin 17 [Homo sapiens]                                    33   0.35 
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]          33   0.46 
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]          33   0.46 
gi|126723390 ankyrin repeat domain 24 [Homo sapiens]                   33   0.46 
gi|14149631 ring finger protein 112 [Homo sapiens]                     33   0.60 
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        32   0.78 
gi|156938343 talin 2 [Homo sapiens]                                    32   0.78 
gi|223029410 talin 1 [Homo sapiens]                                    32   1.0  
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]            32   1.0  
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]            32   1.0  
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]           31   1.7  
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]        31   2.3  
gi|155969697 keratin 6C [Homo sapiens]                                 31   2.3  
gi|5031839 keratin 6A [Homo sapiens]                                   31   2.3  
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ...    31   2.3  

>gi|22035646 apolipoprotein L3 isoform 1 [Homo sapiens]
          Length = 402

 Score =  785 bits (2026), Expect = 0.0
 Identities = 402/402 (100%), Positives = 402/402 (100%)

Query: 1   MGLGQGWGWEASCFACLIRSCCQVVTFTFPFGFQGISQSLENVSGYYADARLEVGSTQLR 60
           MGLGQGWGWEASCFACLIRSCCQVVTFTFPFGFQGISQSLENVSGYYADARLEVGSTQLR
Sbjct: 1   MGLGQGWGWEASCFACLIRSCCQVVTFTFPFGFQGISQSLENVSGYYADARLEVGSTQLR 60

Query: 61  TAGSCSHSFKRSFLEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEA 120
           TAGSCSHSFKRSFLEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEA
Sbjct: 61  TAGSCSHSFKRSFLEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEA 120

Query: 121 DALYEALKKLRTYAAIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEV 180
           DALYEALKKLRTYAAIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEV
Sbjct: 121 DALYEALKKLRTYAAIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEV 180

Query: 181 HRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIV 240
           HRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIV
Sbjct: 181 HRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIV 240

Query: 241 EHSYTSSAEAEASRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQ 300
           EHSYTSSAEAEASRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQ
Sbjct: 241 EHSYTSSAEAEASRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQ 300

Query: 301 ARARARLPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYES 360
           ARARARLPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYES
Sbjct: 301 ARARARLPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYES 360

Query: 361 KHLHEGAKSASAEELRRQAQELEENLMELTQIYQRLNPCHTH 402
           KHLHEGAKSASAEELRRQAQELEENLMELTQIYQRLNPCHTH
Sbjct: 361 KHLHEGAKSASAEELRRQAQELEENLMELTQIYQRLNPCHTH 402


>gi|22035650 apolipoprotein L3 isoform 3 [Homo sapiens]
          Length = 202

 Score =  384 bits (985), Expect = e-106
 Identities = 202/202 (100%), Positives = 202/202 (100%)

Query: 201 MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 260
           MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI
Sbjct: 1   MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 60

Query: 261 DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGG 320
           DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGG
Sbjct: 61  DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGG 120

Query: 321 QAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQ 380
           QAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQ
Sbjct: 121 QAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQ 180

Query: 381 ELEENLMELTQIYQRLNPCHTH 402
           ELEENLMELTQIYQRLNPCHTH
Sbjct: 181 ELEENLMELTQIYQRLNPCHTH 202


>gi|22035648 apolipoprotein L3 isoform 3 [Homo sapiens]
          Length = 202

 Score =  384 bits (985), Expect = e-106
 Identities = 202/202 (100%), Positives = 202/202 (100%)

Query: 201 MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 260
           MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI
Sbjct: 1   MSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSI 60

Query: 261 DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGG 320
           DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGG
Sbjct: 61  DRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGG 120

Query: 321 QAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQ 380
           QAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQ
Sbjct: 121 QAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQ 180

Query: 381 ELEENLMELTQIYQRLNPCHTH 402
           ELEENLMELTQIYQRLNPCHTH
Sbjct: 181 ELEENLMELTQIYQRLNPCHTH 202


>gi|19923626 apolipoprotein L4 isoform 1 [Homo sapiens]
          Length = 348

 Score =  374 bits (961), Expect = e-104
 Identities = 195/324 (60%), Positives = 249/324 (76%), Gaps = 4/324 (1%)

Query: 73  FLEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRT 132
           F EKKRFTEE  +YF+++VSPVHL+ILLT++EAWKRFV  AELPR+EADALYEALK L  
Sbjct: 26  FQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTP 85

Query: 133 YAAIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSS 192
           Y AIED+ +QQK++QFREWFLKEFPQ++ KIQESIE+LR +AN IE+VHRGC I+NVVS 
Sbjct: 86  YVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSG 145

Query: 193 STGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEA 252
           STG    I+S+ G++LAPFTAG SL++TAAGVGLG ASA  GI +SIVE++YT SAE  A
Sbjct: 146 STG----ILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTA 201

Query: 253 SRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTW 312
           SRLTATS D+L+  ++++RDITPN+LS   ++ EAT+ I +++  +R+++A    P+  W
Sbjct: 202 SRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSKATVGRPLIAW 261

Query: 313 RISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASA 372
           R    +  +  RT    TR V + AR L   TSG+ + LDVVNLV +S  LH+GAKS SA
Sbjct: 262 RYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESA 321

Query: 373 EELRRQAQELEENLMELTQIYQRL 396
           E LR+ AQELEENL ELT I+Q L
Sbjct: 322 ESLRQWAQELEENLNELTHIHQSL 345


>gi|22035657 apolipoprotein L4 isoform 2 precursor [Homo sapiens]
          Length = 351

 Score =  374 bits (961), Expect = e-104
 Identities = 195/324 (60%), Positives = 249/324 (76%), Gaps = 4/324 (1%)

Query: 73  FLEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRT 132
           F EKKRFTEE  +YF+++VSPVHL+ILLT++EAWKRFV  AELPR+EADALYEALK L  
Sbjct: 29  FQEKKRFTEEVIEYFQKKVSPVHLKILLTSDEAWKRFVRVAELPREEADALYEALKNLTP 88

Query: 133 YAAIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSS 192
           Y AIED+ +QQK++QFREWFLKEFPQ++ KIQESIE+LR +AN IE+VHRGC I+NVVS 
Sbjct: 89  YVAIEDKDMQQKEQQFREWFLKEFPQIRWKIQESIERLRVIANEIEKVHRGCVIANVVSG 148

Query: 193 STGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEA 252
           STG    I+S+ G++LAPFTAG SL++TAAGVGLG ASA  GI +SIVE++YT SAE  A
Sbjct: 149 STG----ILSVIGVMLAPFTAGLSLSITAAGVGLGIASATAGIASSIVENTYTRSAELTA 204

Query: 253 SRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTW 312
           SRLTATS D+L+  ++++RDITPN+LS   ++ EAT+ I +++  +R+++A    P+  W
Sbjct: 205 SRLTATSTDQLEALRDILRDITPNVLSFALDFDEATKMIANDVHTLRRSKATVGRPLIAW 264

Query: 313 RISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASA 372
           R    +  +  RT    TR V + AR L   TSG+ + LDVVNLV +S  LH+GAKS SA
Sbjct: 265 RYVPINVVETLRTRGAPTRIVRKVARNLGKATSGVLVVLDVVNLVQDSLDLHKGAKSESA 324

Query: 373 EELRRQAQELEENLMELTQIYQRL 396
           E LR+ AQELEENL ELT I+Q L
Sbjct: 325 ESLRQWAQELEENLNELTHIHQSL 348


>gi|13562090 apolipoprotein L2 [Homo sapiens]
          Length = 337

 Score =  317 bits (811), Expect = 2e-86
 Identities = 174/330 (52%), Positives = 227/330 (68%), Gaps = 6/330 (1%)

Query: 75  EKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRTYA 134
           E   F E+  KYF+++VS  +L  LLT++EAW  FV AAELPRDEAD L +AL KL ++ 
Sbjct: 4   ESSIFIEDYLKYFQDQVSRENLLQLLTDDEAWNGFVAAAELPRDEADELRKALNKLASHM 63

Query: 135 AIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSSST 194
            ++D+    KD+Q R+WFLKEFP++KR++++ I KLRALA  +E+VHRG TI+NVVS+S 
Sbjct: 64  VMKDKNRHDKDQQHRQWFLKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSV 123

Query: 195 GAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASR 254
           G  SGI++L GL LAPFT G S  L   G+GLGAA+AV GIT S+VE      A A+A  
Sbjct: 124 GTTSGILTLLGLGLAPFTEGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARN 183

Query: 255 LTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARL------P 308
           L  +  +  KV KE +   TPN+L+L++N+Y+ TQ IG  IRAIR+ARA  +L      P
Sbjct: 184 LDQSGTNVAKVMKEFVGGNTPNVLTLVDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPP 243

Query: 309 VTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAK 368
               RISA  G Q ER + G  +A+SRG  I+ A T GI L LDVV+L YESKHL EGAK
Sbjct: 244 HIIGRISAEGGEQVERVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLEGAK 303

Query: 369 SASAEELRRQAQELEENLMELTQIYQRLNP 398
           S SAEEL+++AQELE  L  LT+I++ L P
Sbjct: 304 SESAEELKKRAQELEGKLNFLTKIHEMLQP 333


>gi|22035653 apolipoprotein L2 [Homo sapiens]
          Length = 337

 Score =  317 bits (811), Expect = 2e-86
 Identities = 174/330 (52%), Positives = 227/330 (68%), Gaps = 6/330 (1%)

Query: 75  EKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRTYA 134
           E   F E+  KYF+++VS  +L  LLT++EAW  FV AAELPRDEAD L +AL KL ++ 
Sbjct: 4   ESSIFIEDYLKYFQDQVSRENLLQLLTDDEAWNGFVAAAELPRDEADELRKALNKLASHM 63

Query: 135 AIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSSST 194
            ++D+    KD+Q R+WFLKEFP++KR++++ I KLRALA  +E+VHRG TI+NVVS+S 
Sbjct: 64  VMKDKNRHDKDQQHRQWFLKEFPRLKRELEDHIRKLRALAEEVEQVHRGTTIANVVSNSV 123

Query: 195 GAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASR 254
           G  SGI++L GL LAPFT G S  L   G+GLGAA+AV GIT S+VE      A A+A  
Sbjct: 124 GTTSGILTLLGLGLAPFTEGISFVLLDTGMGLGAAAAVAGITCSVVELVNKLRARAQARN 183

Query: 255 LTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARL------P 308
           L  +  +  KV KE +   TPN+L+L++N+Y+ TQ IG  IRAIR+ARA  +L      P
Sbjct: 184 LDQSGTNVAKVMKEFVGGNTPNVLTLVDNWYQVTQGIGRNIRAIRRARANPQLGAYAPPP 243

Query: 309 VTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAK 368
               RISA  G Q ER + G  +A+SRG  I+ A T GI L LDVV+L YESKHL EGAK
Sbjct: 244 HIIGRISAEGGEQVERVVEGPAQAMSRGTMIVGAATGGILLLLDVVSLAYESKHLLEGAK 303

Query: 369 SASAEELRRQAQELEENLMELTQIYQRLNP 398
           S SAEEL+++AQELE  L  LT+I++ L P
Sbjct: 304 SESAEELKKRAQELEGKLNFLTKIHEMLQP 333


>gi|211938442 apolipoprotein L1 isoform c precursor [Homo sapiens]
          Length = 380

 Score =  283 bits (725), Expect = 1e-76
 Identities = 157/330 (47%), Positives = 215/330 (65%), Gaps = 8/330 (2%)

Query: 75  EKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRTYA 134
           E   F E+A KYF+E+VS  +L +LLT+NEAW  FV AAELPR+EAD L +AL  L    
Sbjct: 45  ESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQM 104

Query: 135 AIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSSST 194
            ++D+    K +Q+R WFLKEFP++K +++++I +LRALA+G+++VH+G TI+NVVS S 
Sbjct: 105 IMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSL 164

Query: 195 GAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASR 254
             +SGI++L G+ LAPFT G SL L   G+ LG  +A+TGIT+S +++      +A+A  
Sbjct: 165 SISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHD 224

Query: 255 LTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARAR--------AR 306
           L   S+D+LK  +E + +   N LSL  N Y+ T+ IG +IRA+R+ARA         A 
Sbjct: 225 LVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASAS 284

Query: 307 LPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEG 366
            P  T  ISA SG Q ER    +   +SRG ++        FL LDVV LVYESKHLHEG
Sbjct: 285 RPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEG 344

Query: 367 AKSASAEELRRQAQELEENLMELTQIYQRL 396
           AKS +AEEL++ AQELEE L  L   Y+ L
Sbjct: 345 AKSETAEELKKVAQELEEKLNILNNNYKIL 374


>gi|211938440 apolipoprotein L1 isoform a precursor [Homo sapiens]
          Length = 398

 Score =  283 bits (725), Expect = 1e-76
 Identities = 157/330 (47%), Positives = 215/330 (65%), Gaps = 8/330 (2%)

Query: 75  EKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRTYA 134
           E   F E+A KYF+E+VS  +L +LLT+NEAW  FV AAELPR+EAD L +AL  L    
Sbjct: 63  ESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQM 122

Query: 135 AIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSSST 194
            ++D+    K +Q+R WFLKEFP++K +++++I +LRALA+G+++VH+G TI+NVVS S 
Sbjct: 123 IMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSL 182

Query: 195 GAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASR 254
             +SGI++L G+ LAPFT G SL L   G+ LG  +A+TGIT+S +++      +A+A  
Sbjct: 183 SISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHD 242

Query: 255 LTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARAR--------AR 306
           L   S+D+LK  +E + +   N LSL  N Y+ T+ IG +IRA+R+ARA         A 
Sbjct: 243 LVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASAS 302

Query: 307 LPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEG 366
            P  T  ISA SG Q ER    +   +SRG ++        FL LDVV LVYESKHLHEG
Sbjct: 303 RPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEG 362

Query: 367 AKSASAEELRRQAQELEENLMELTQIYQRL 396
           AKS +AEEL++ AQELEE L  L   Y+ L
Sbjct: 363 AKSETAEELKKVAQELEEKLNILNNNYKIL 392


>gi|21735616 apolipoprotein L1 isoform b precursor [Homo sapiens]
          Length = 414

 Score =  283 bits (725), Expect = 1e-76
 Identities = 157/330 (47%), Positives = 215/330 (65%), Gaps = 8/330 (2%)

Query: 75  EKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRTYA 134
           E   F E+A KYF+E+VS  +L +LLT+NEAW  FV AAELPR+EAD L +AL  L    
Sbjct: 79  ESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQM 138

Query: 135 AIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSSST 194
            ++D+    K +Q+R WFLKEFP++K +++++I +LRALA+G+++VH+G TI+NVVS S 
Sbjct: 139 IMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSL 198

Query: 195 GAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASR 254
             +SGI++L G+ LAPFT G SL L   G+ LG  +A+TGIT+S +++      +A+A  
Sbjct: 199 SISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHD 258

Query: 255 LTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARAR--------AR 306
           L   S+D+LK  +E + +   N LSL  N Y+ T+ IG +IRA+R+ARA         A 
Sbjct: 259 LVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASAS 318

Query: 307 LPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEG 366
            P  T  ISA SG Q ER    +   +SRG ++        FL LDVV LVYESKHLHEG
Sbjct: 319 RPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEG 378

Query: 367 AKSASAEELRRQAQELEENLMELTQIYQRL 396
           AKS +AEEL++ AQELEE L  L   Y+ L
Sbjct: 379 AKSETAEELKKVAQELEEKLNILNNNYKIL 408


>gi|21735614 apolipoprotein L1 isoform a precursor [Homo sapiens]
          Length = 398

 Score =  283 bits (725), Expect = 1e-76
 Identities = 157/330 (47%), Positives = 215/330 (65%), Gaps = 8/330 (2%)

Query: 75  EKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALKKLRTYA 134
           E   F E+A KYF+E+VS  +L +LLT+NEAW  FV AAELPR+EAD L +AL  L    
Sbjct: 63  ESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQM 122

Query: 135 AIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSSST 194
            ++D+    K +Q+R WFLKEFP++K +++++I +LRALA+G+++VH+G TI+NVVS S 
Sbjct: 123 IMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSL 182

Query: 195 GAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASR 254
             +SGI++L G+ LAPFT G SL L   G+ LG  +A+TGIT+S +++      +A+A  
Sbjct: 183 SISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHD 242

Query: 255 LTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARAR--------AR 306
           L   S+D+LK  +E + +   N LSL  N Y+ T+ IG +IRA+R+ARA         A 
Sbjct: 243 LVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASAS 302

Query: 307 LPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEG 366
            P  T  ISA SG Q ER    +   +SRG ++        FL LDVV LVYESKHLHEG
Sbjct: 303 RPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEG 362

Query: 367 AKSASAEELRRQAQELEENLMELTQIYQRL 396
           AKS +AEEL++ AQELEE L  L   Y+ L
Sbjct: 363 AKSETAEELKKVAQELEEKLNILNNNYKIL 392


>gi|13449281 apolipoprotein L6 [Homo sapiens]
          Length = 343

 Score =  167 bits (424), Expect = 1e-41
 Identities = 111/302 (36%), Positives = 160/302 (52%), Gaps = 18/302 (5%)

Query: 102 NNEAWKRFVTAAELPRDEADALYEALKKLRTYAAIEDEYVQQKDEQFREW-FLKEFPQVK 160
           +N+A +       L RDE DA              ED  +Q  D    E  FL+EFP++K
Sbjct: 2   DNQAERESEAGVGLQRDEDDA-----------PLCEDVELQDGDLSPEEKIFLREFPRLK 50

Query: 161 RKIQESIEKLRALANGIEEVHRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALT 220
             ++ +I+KLRALA+ I++ H+  T +N+V++ST   SG+MSL GL LAP T G SL L+
Sbjct: 51  EDLKGNIDKLRALADDIDKTHKKFTKANMVATSTAVISGVMSLLGLALAPATGGGSLLLS 110

Query: 221 AAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLKVFKEVMRDITPNLLSL 280
            AG GL  A+ VT I +  +E S    A+A A  +  T     +  +E   D       +
Sbjct: 111 TAGQGLATAAGVTSIVSGTLERSKNKEAQARAEDILPTYDQEDREDEEEKADYVTAAGKI 170

Query: 281 LNNYYEATQTIGSEIRAIRQARARARLP------VTTWRISAGSGGQAERTIAGTTRAVS 334
           + N     +     +RA  + RA  RL       +TT ++S+ S  Q ++  AGTT A++
Sbjct: 171 IYNLRNTLKYAKKNVRAFWKLRANPRLANATKRLLTTGQVSSRSRVQVQKAFAGTTLAMT 230

Query: 335 RGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQELEENLMELTQIYQ 394
           + AR+L    S   L  D+  L  E KHL EGA++  AEELR +A ELE  L ELTQ+Y+
Sbjct: 231 KNARVLGGVMSAFSLGYDLATLSKEWKHLKEGARTKFAEELRAKALELERKLTELTQLYK 290

Query: 395 RL 396
            L
Sbjct: 291 SL 292


>gi|13470094 apolipoprotein L5 [Homo sapiens]
          Length = 433

 Score =  135 bits (340), Expect = 7e-32
 Identities = 87/251 (34%), Positives = 143/251 (56%), Gaps = 8/251 (3%)

Query: 152 FLKEFPQVKRKIQESIEKLRALANGIEEVHRGCTISNVVSSSTGAASGIMSLAGLVLAPF 211
           FL  FP  K +++++I++L  LA+ ++  H   T +++V+SS+GA SG+M++ GL LAP 
Sbjct: 102 FLSYFPLHKFELEQNIKELNTLADQVDTTHELLTKTSLVASSSGAVSGVMNILGLALAPV 161

Query: 212 TAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLKVFKEVMR 271
           TAG SL L+A G GLGAA+A+T I T+++E+   S+A  +ASRL   +    + F  +  
Sbjct: 162 TAGGSLMLSATGTGLGAAAAITNIVTNVLENRSNSAARDKASRLGPLTTSH-EAFGGINW 220

Query: 272 DITPNLLSLLNNYYEATQTIGSEIRAIRQAR------ARARLPVTTWRISAGSGGQAERT 325
                    +N   +A Q I  ++ A + A+      A  +  V    I   +    +R 
Sbjct: 221 SEIEAAGFCVNKCVKAIQGI-KDLHAYQMAKSNSGFMAMVKNFVAKRHIPFWTARGVQRA 279

Query: 326 IAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEELRRQAQELEEN 385
             GTT A++ GA ++ A  +G  L  D+ + +   KHL +GA++ +AEELR  A++LE+ 
Sbjct: 280 FEGTTLAMTNGAWVMGAAGAGFLLMKDMSSFLQSWKHLEDGARTETAEELRALAKKLEQE 339

Query: 386 LMELTQIYQRL 396
           L  LTQ ++ L
Sbjct: 340 LDRLTQHHRHL 350


>gi|194353995 apolipoprotein L domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 279

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 29/103 (28%), Positives = 52/103 (50%)

Query: 162 KIQESIEKLRALANGIEEVHRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALTA 221
           ++   + +LR +A  +E + R   ++NV  SS  A   + ++ GL L+P T GTSL ++A
Sbjct: 61  RLHGQVLRLREVARRLERLRRRSLVANVAGSSLSATGALAAIVGLSLSPVTLGTSLLVSA 120

Query: 222 AGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLK 264
            G+G+  A     IT+ +      S        + AT  D+++
Sbjct: 121 VGLGVATAGGAVTITSDLSLIFCNSRELRRVQEIAATCQDQMR 163


>gi|194353993 apolipoprotein L domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 248

 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 29/103 (28%), Positives = 52/103 (50%)

Query: 162 KIQESIEKLRALANGIEEVHRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALTA 221
           ++   + +LR +A  +E + R   ++NV  SS  A   + ++ GL L+P T GTSL ++A
Sbjct: 30  RLHGQVLRLREVARRLERLRRRSLVANVAGSSLSATGALAAIVGLSLSPVTLGTSLLVSA 89

Query: 222 AGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLK 264
            G+G+  A     IT+ +      S        + AT  D+++
Sbjct: 90  VGLGVATAGGAVTITSDLSLIFCNSRELRRVQEIAATCQDQMR 132


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 33.5 bits (75), Expect = 0.35
 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 8/156 (5%)

Query: 187  SNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTS 246
            S  VSSS   A G            TA TS+ ++   V     + ++  T ++     T+
Sbjct: 1842 STAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLS-TTPAVTSTPVTT 1900

Query: 247  SAEAEASRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARAR 306
             A+  +S  TA   D   +     R+  P L S+       T    SEI  +    A  R
Sbjct: 1901 YAQVSSSPTTA---DGSSMPTSTPREGRPPLTSIP---VSTTTVASSEINTLSTTLADTR 1954

Query: 307  LPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSA 342
             PVTT+  ++ S   A+ T +  T A S G+  L++
Sbjct: 1955 TPVTTYSQASSSPTTADGT-SMPTPAYSEGSTPLTS 1989



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 37/158 (23%), Positives = 62/158 (39%), Gaps = 9/158 (5%)

Query: 189  VVSSSTGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITT-SIVEHSYTSS 247
            V+SS     S         +   T  TS   TA G  +  ++   G+T  +    S+T  
Sbjct: 1761 VLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLV 1820

Query: 248  AEAEASRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARL 307
            A +EAS L+ T +D           +T   +S      E T    S       + A   +
Sbjct: 1821 ANSEASTLSTTPVDSNSPV------VTSTAVSSSPTPAEGTSIATS--TPSEGSTALTSI 1872

Query: 308  PVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTS 345
            PV+T  +++        T A T+  V+  A++ S+ T+
Sbjct: 1873 PVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTT 1910



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 9/158 (5%)

Query: 189  VVSSSTGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITT-SIVEHSYTSS 247
            VVSS     S         +   T  TS   TA G  +  ++   G T  +    S+T  
Sbjct: 936  VVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLV 995

Query: 248  AEAEASRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARL 307
            A +EAS L+ T +D            +P   +   +   +T + GS            R+
Sbjct: 996  ANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGS--------TPLTRM 1047

Query: 308  PVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTS 345
            PV+T  +++        T A T+  V+  ++  S++T+
Sbjct: 1048 PVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTT 1085


>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
          Length = 1668

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 24/134 (17%), Positives = 53/134 (39%), Gaps = 4/134 (2%)

Query: 256 TATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRIS 315
           +A  +++++  +   +D+   LL    NY  A    GS+I  + +          T +  
Sbjct: 244 SAGLLEQMRHMETQAKDLRNQLL----NYRSAISNHGSKIEGLERELTDLNQEFETLQEK 299

Query: 316 AGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEEL 375
           A    +  +T+       ++ A+ L      +   + ++N +   +  H+G  +  A  +
Sbjct: 300 AQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSI 359

Query: 376 RRQAQELEENLMEL 389
           R    E E  L +L
Sbjct: 360 RDSLNEYEAKLSDL 373


>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
          Length = 3277

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 24/134 (17%), Positives = 53/134 (39%), Gaps = 4/134 (2%)

Query: 256  TATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRIS 315
            +A  +++++  +   +D+   LL    NY  A    GS+I  + +          T +  
Sbjct: 1853 SAGLLEQMRHMETQAKDLRNQLL----NYRSAISNHGSKIEGLERELTDLNQEFETLQEK 1908

Query: 316  AGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESKHLHEGAKSASAEEL 375
            A    +  +T+       ++ A+ L      +   + ++N +   +  H+G  +  A  +
Sbjct: 1909 AQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSI 1968

Query: 376  RRQAQELEENLMEL 389
            R    E E  L +L
Sbjct: 1969 RDSLNEYEAKLSDL 1982


>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
          Length = 1146

 Score = 33.1 bits (74), Expect = 0.46
 Identities = 62/253 (24%), Positives = 103/253 (40%), Gaps = 28/253 (11%)

Query: 155 EFPQVKRKIQESIEKLRALANGIEEVHRGCTIS-NVVSSSTGAASGI--MSLAGLVLAPF 211
           EF Q++R+  E+++ LR           G     + V+ +T   +G   M L G V AP 
Sbjct: 495 EFDQLRRQHAEALQALRQQETREVPREEGAACGESEVAGATATKNGPTHMELNGSV-APE 553

Query: 212 T---AGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLKVFKE 268
           T      ++   AAG     A  +    T     +  + AEA  +++T T     +V + 
Sbjct: 554 TKVNGAETIDEEAAGDETMEARTMEAEATG----AEATGAEATGAKVTETKPTGAEVREM 609

Query: 269 VMRDITPNLLSLLNNYYEA-TQTIGSEIRAIRQARARAR-LPVTTWRISAGSGGQAERTI 326
              +   N+ +         T+T G E   +   + +A    +  + + AG   QAE  +
Sbjct: 610 ETTEEEANMETKPTGAQATDTETTGVEAMGVEATKTKAEEAEMQAYGVGAG---QAEPPV 666

Query: 327 AGTTRAVSRGARILSATTSGIFLALDVVNLVYES--------KHLHEGAKSASAE---EL 375
            GTT   + G+R     ++G+  A  V N   E+          LH GA  AS +   EL
Sbjct: 667 TGTTNMEATGSRATGMESTGV-SATGVENPGVEATVPGISAGPILHPGAAEASEKLQVEL 725

Query: 376 RRQAQELEENLME 388
             + + LEE L +
Sbjct: 726 ETRIRGLEEALRQ 738


>gi|14149631 ring finger protein 112 [Homo sapiens]
          Length = 632

 Score = 32.7 bits (73), Expect = 0.60
 Identities = 40/146 (27%), Positives = 58/146 (39%), Gaps = 31/146 (21%)

Query: 118 DEADALYEALKKLRTYAAIEDEYVQQKDEQFREWF--LKEFPQVKRKIQ----------- 164
           DE  A    L+K+       +EYV+Q+D   +  F  L+  P   R +            
Sbjct: 450 DEMAAQLHDLRKVEAAKREFEEYVRQQDVATKRIFSALRVLPDTMRNLLSTQKDAILARH 509

Query: 165 -------------ESIE-KLRALANGIEEVH--RGCTISNVVSSSTGAASGIMSLAGLVL 208
                        E++E +L+A A    + +  R C     V  + GA  G+M LAG V+
Sbjct: 510 GVALLCKGRDQTLEALEAELQATAKAFMDSYTMRFCGHLAAVGGAVGA--GLMGLAGGVV 567

Query: 209 APFTAGTSLALTAAGVGLGAASAVTG 234
               A  +LA  A  V  GAA   TG
Sbjct: 568 GAGMAAAALAAEAGMVAAGAAVGATG 593


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 32.3 bits (72), Expect = 0.78
 Identities = 51/202 (25%), Positives = 77/202 (38%), Gaps = 37/202 (18%)

Query: 200  IMSLAGLVLAP--FTAGTSLALTAAGVG----------LGAASAVTGITTSIVEHSYTSS 247
            +MS  G  L    F+AG  L L  A  G          L    A++G+  + +E S  S 
Sbjct: 941  VMSSGGQALRSEEFSAGGELGLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSG 1000

Query: 248  AEAEA-SRLTATSIDRLKVFKEVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARAR 306
            A  E  S +   S+       +    ++P     L    E   TI     A+  +R R+R
Sbjct: 1001 APRETPSEMATNSLPNGPALADGPAPVSP-----LEPSPEKVATISPRRHAMPGSRPRSR 1055

Query: 307  LPVTTWRISAGSGGQAERTIAGTTRAVSRGARILSATTSGIFLALDVVNLVYESK----- 361
            +PV       GS        +G+  A  R ++             D+  LV E +     
Sbjct: 1056 IPVLLSEEDTGS------EPSGSLSAKERWSKRARPQQ-------DLARLVMEKRQGRLL 1102

Query: 362  -HLHEGAKSASAEELRRQAQEL 382
              L  GA S+S+EE RR ++ L
Sbjct: 1103 LRLASGASSSSSEEQRRASETL 1124


>gi|156938343 talin 2 [Homo sapiens]
          Length = 2542

 Score = 32.3 bits (72), Expect = 0.78
 Identities = 41/190 (21%), Positives = 76/190 (40%), Gaps = 16/190 (8%)

Query: 208  LAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLKVFK 267
            +A  T+    + +AA   L A   V  I  +  +    S     A+R+ A +        
Sbjct: 2353 IAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARMVAAA-------- 2404

Query: 268  EVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGGQAERTIA 327
                  T +L    N   +   +    I + +Q  A     +   ++ A    +A R + 
Sbjct: 2405 ------TSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQ 2458

Query: 328  GTTRAVSRGA-RILSATTSGIFLALDVVNLVYESKHLHEGAKSASA-EELRRQAQELEEN 385
                AV R +  ++ A     F   D  ++V ++K +   A+  +A EE+ ++ +ELEE 
Sbjct: 2459 AAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEA 2518

Query: 386  LMELTQIYQR 395
              +L QI Q+
Sbjct: 2519 RKKLAQIRQQ 2528


>gi|223029410 talin 1 [Homo sapiens]
          Length = 2541

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 43/191 (22%), Positives = 76/191 (39%), Gaps = 17/191 (8%)

Query: 208  LAPFTAGTSLALTAAGVGLGAASAVTGITTSIVEHSYTSSAEAEASRLTATSIDRLKVFK 267
            +A  T+    A +AA   L A   V  I  + ++    S     A+R+ A +        
Sbjct: 2352 IAAATSALVKAASAAQRELVAQGKVGAIPANALDDGQWSQGLISAARMVAAA-------- 2403

Query: 268  EVMRDITPNLLSLLNNYYEATQTIGSEIRAIRQARARARLPVTTWRISAGSGGQAERTIA 327
                  T NL    N   +   +    I + +Q  A     +   ++ A    +A + + 
Sbjct: 2404 ------TNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQ 2457

Query: 328  GTTRAVSRGARIL--SATTSGIFLALDVVNLVYESKHLHEGAKSASA-EELRRQAQELEE 384
                AV R +  L  +A  +  F   +   +V + K +   A+  +A EE+ R+ +ELEE
Sbjct: 2458 AAGNAVKRASDNLVKAAQKAAAFEEQENETVVVKEKMVGGIAQIIAAQEEMLRKERELEE 2517

Query: 385  NLMELTQIYQR 395
               +L QI Q+
Sbjct: 2518 ARKKLAQIRQQ 2528


>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 19/79 (24%), Positives = 37/79 (46%)

Query: 181 HRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIV 240
           H    I++  S+S+ + +   S +  + + FT  TS+  T++      ++A T  + SI 
Sbjct: 105 HHTLHITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISIT 164

Query: 241 EHSYTSSAEAEASRLTATS 259
             S  SS+    S  T ++
Sbjct: 165 STSSISSSITSTSTSTTST 183


>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 737

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 19/79 (24%), Positives = 37/79 (46%)

Query: 181 HRGCTISNVVSSSTGAASGIMSLAGLVLAPFTAGTSLALTAAGVGLGAASAVTGITTSIV 240
           H    I++  S+S+ + +   S +  + + FT  TS+  T++      ++A T  + SI 
Sbjct: 105 HHTLHITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSSTSSFTTSTATTSTSISIT 164

Query: 241 EHSYTSSAEAEASRLTATS 259
             S  SS+    S  T ++
Sbjct: 165 STSSISSSITSTSTSTTST 183


>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
          Length = 1989

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 10/130 (7%)

Query: 53  EVGSTQLRTAGSCSHSFKRSFLEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTA 112
           E+   QLR     S S K    E++   E   K  + +     ++     + A K   TA
Sbjct: 368 ELSELQLRLLALQSASKKWQQKEQQVMKESKEKLTKTKTVQQKVKTSTKTHSAKKVSTTA 427

Query: 113 AELPRDEADALYEALKKLRTYAAIEDEYVQQKDEQFREWFLKEFPQVKRKIQESIEKLRA 172
            +  R +    ++ L++       + E  +QK+E  R+   +E    +RK +E I K+R 
Sbjct: 428 KQALRKQQTKAWKKLQQ-------QKEQERQKEEDQRKQAEEE---ERRKREEEIRKIRD 477

Query: 173 LANGIEEVHR 182
           L+N  E+ +R
Sbjct: 478 LSNQEEQYNR 487


>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
          Length = 679

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 25/114 (21%), Positives = 50/114 (43%), Gaps = 4/114 (3%)

Query: 59  LRTAGSCSHSFKRSFLEKKRFTEEATKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRD 118
           ++++G  S     + ++      E  +  +ERV  V++   + ++   K      +LP D
Sbjct: 547 IQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPAD 606

Query: 119 EADALYEALKKLRTYAAIED----EYVQQKDEQFREWFLKEFPQVKRKIQESIE 168
           E + L E + K+R   A +D    E ++Q     ++  LK F    +K+    E
Sbjct: 607 ECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEMAYKKMASERE 660


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 37/150 (24%), Positives = 71/150 (47%), Gaps = 26/150 (17%)

Query: 122 ALYEALKKLRTYAAIEDEYVQQKDEQFREWFLKEFPQVK-------------RKIQESIE 168
           AL +A  KL     +ED   + K +  R   LKE+ ++              RK+ E  E
Sbjct: 419 ALKDAKNKLE---GLEDALQKAKQDLAR--LLKEYQELMNVKLALDVEIATYRKLLEG-E 472

Query: 169 KLRALANGIEEVHRGCTISNVVSSSTGAASGIMSLAGL-VLAPFTAGTSLAL-----TAA 222
           + R    G+ +V+    + + +SS  G ASG+ S  GL   + ++ G+ L +     +++
Sbjct: 473 ECRLNGEGVGQVNVS-VVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSS 531

Query: 223 GVGLGAASAVTGITTSIVEHSYTSSAEAEA 252
           G  +G   +  G  +S ++++ TSS+  ++
Sbjct: 532 GRAIGGGLSSVGGGSSTIKYTTTSSSSRKS 561


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 38/150 (25%), Positives = 71/150 (47%), Gaps = 26/150 (17%)

Query: 122 ALYEALKKLRTYAAIEDEYVQQKDEQFREWFLKEFPQVK-------------RKIQESIE 168
           AL +A  KL     +ED   + K +  R   LKE+ ++              RK+ E  E
Sbjct: 419 ALKDAKNKLE---GLEDALQKAKQDLAR--LLKEYQELMNVKLALDVEIATYRKLLEG-E 472

Query: 169 KLRALANGIEEVHRGCTISNVVSSSTGAASGIMSLAGL-VLAPFTAGTSLAL-----TAA 222
           + R    G+ +V+    + + VSS  G ASG+ S  GL   + ++ G+ L +     +++
Sbjct: 473 ECRLNGEGVGQVNIS-VVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSS 531

Query: 223 GVGLGAASAVTGITTSIVEHSYTSSAEAEA 252
           G  +G   +  G  +S ++++ TSS+  ++
Sbjct: 532 GRAIGGGLSSVGGGSSTIKYTTTSSSSRKS 561


>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3
           [Homo sapiens]
          Length = 1585

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 17/131 (12%)

Query: 80  TEEA--TKYFRERVSPVHLQILLTNNEAWKRFVTAAELPRDEADALYEALK-----KLRT 132
           TEE   ++    R SPV  QI +T  + WK+       P+D      E L+     K   
Sbjct: 481 TEEILDSQNLNSRRSPVPAQIAITVPKTWKK-------PKDRTRTTEEMLEAELELKAEE 533

Query: 133 YAAIEDEYVQQKDEQFREWFLKEFPQVKRK---IQESIEKLRALANGIEEVHRGCTISNV 189
             +I+     ++D+  + +  +  P   +K   ++E+ E+   + NG E V  G  I   
Sbjct: 534 ELSIDKVLESEQDKMSQGFHPERDPSDLKKVKAVEENGEEAEPVRNGAESVSEGEGIDAN 593

Query: 190 VSSSTGAASGI 200
             S+  +  G+
Sbjct: 594 SGSTDSSGDGV 604


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.129    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,507,890
Number of Sequences: 37866
Number of extensions: 477792
Number of successful extensions: 2559
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 2488
Number of HSP's gapped (non-prelim): 103
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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