Search of human proteins with 22035569

Search of human proteins with 22035569

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035569 GC-rich sequence DNA-binding factor candidate
isoform 2 [Homo sapiens]
         (815 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035569 GC-rich sequence DNA-binding factor candidate isofor...  1641   0.0  
gi|22035565 GC-rich sequence DNA-binding factor candidate isofor...  1560   0.0  
gi|44890065 hypothetical protein LOC6936 [Homo sapiens]               333   4e-91
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    48   3e-05
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        47   5e-05
gi|33946313 ninein isoform 4 [Homo sapiens]                            46   2e-04
gi|33946321 ninein isoform 5 [Homo sapiens]                            46   2e-04
gi|148536871 ninein isoform 1 [Homo sapiens]                           46   2e-04
gi|148536869 ninein isoform 2 [Homo sapiens]                           46   2e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    45   3e-04
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    45   3e-04
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    45   3e-04
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    45   3e-04
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    45   4e-04
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    44   5e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    44   6e-04
gi|32171221 GRP1 (general receptor for phosphoinositides 1)-asso...    44   6e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    44   8e-04
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...    44   8e-04
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                43   0.001
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    43   0.001
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    43   0.001
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               42   0.002
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                42   0.002
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 42   0.002
gi|38788333 remodeling and spacing factor 1 [Homo sapiens]             42   0.002
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform...    42   0.002
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  42   0.002
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    42   0.002
gi|7661950 SH2 domain binding protein 1 [Homo sapiens]                 42   0.002

>gi|22035569 GC-rich sequence DNA-binding factor candidate isoform 2
           [Homo sapiens]
          Length = 815

 Score = 1641 bits (4249), Expect = 0.0
 Identities = 815/815 (100%), Positives = 815/815 (100%)

Query: 1   MFRKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPG 60
           MFRKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPG
Sbjct: 1   MFRKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPG 60

Query: 61  PSPPSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVF 120
           PSPPSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVF
Sbjct: 61  PSPPSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVF 120

Query: 121 KVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIIS 180
           KVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIIS
Sbjct: 121 KVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIIS 180

Query: 181 EHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGD 240
           EHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGD
Sbjct: 181 EHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGD 240

Query: 241 FTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDAL 300
           FTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDAL
Sbjct: 241 FTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDAL 300

Query: 301 VTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAY 360
           VTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAY
Sbjct: 301 VTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAY 360

Query: 361 GSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEKHLQSR 420
           GSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEKHLQSR
Sbjct: 361 GSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEKHLQSR 420

Query: 421 VDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLYKQRA 480
           VDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLYKQRA
Sbjct: 421 VDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLYKQRA 480

Query: 481 SRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARRTRRR 540
           SRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARRTRRR
Sbjct: 481 SRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARRTRRR 540

Query: 541 QAREQTGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGKVFEDVLESFYSIDCIKS 600
           QAREQTGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGKVFEDVLESFYSIDCIKS
Sbjct: 541 QAREQTGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGKVFEDVLESFYSIDCIKS 600

Query: 601 QFEAWRSKYYTSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFENMLWFESLLFYG 660
           QFEAWRSKYYTSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFENMLWFESLLFYG
Sbjct: 601 QFEAWRSKYYTSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFENMLWFESLLFYG 660

Query: 661 CEEREQEKDDVDVALLPTIVEKVILPKLTVIAENMWDPFSTTQTSRMVGITLKLINGYPS 720
           CEEREQEKDDVDVALLPTIVEKVILPKLTVIAENMWDPFSTTQTSRMVGITLKLINGYPS
Sbjct: 661 CEEREQEKDDVDVALLPTIVEKVILPKLTVIAENMWDPFSTTQTSRMVGITLKLINGYPS 720

Query: 721 VVNAENKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFWSSVKVI 780
           VVNAENKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFWSSVKVI
Sbjct: 721 VVNAENKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFWSSVKVI 780

Query: 781 KPPFQRGSCPIPRRKECCSERPRRIWTDRPCVVFS 815
           KPPFQRGSCPIPRRKECCSERPRRIWTDRPCVVFS
Sbjct: 781 KPPFQRGSCPIPRRKECCSERPRRIWTDRPCVVFS 815


>gi|22035565 GC-rich sequence DNA-binding factor candidate isoform 1
           [Homo sapiens]
          Length = 917

 Score = 1560 bits (4038), Expect = 0.0
 Identities = 778/780 (99%), Positives = 780/780 (100%)

Query: 1   MFRKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPG 60
           MFRKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPG
Sbjct: 1   MFRKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPG 60

Query: 61  PSPPSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVF 120
           PSPPSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVF
Sbjct: 61  PSPPSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVF 120

Query: 121 KVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIIS 180
           KVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIIS
Sbjct: 121 KVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIIS 180

Query: 181 EHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGD 240
           EHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGD
Sbjct: 181 EHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGD 240

Query: 241 FTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDAL 300
           FTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDAL
Sbjct: 241 FTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDAL 300

Query: 301 VTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAY 360
           VTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAY
Sbjct: 301 VTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAY 360

Query: 361 GSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEKHLQSR 420
           GSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEKHLQSR
Sbjct: 361 GSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEKHLQSR 420

Query: 421 VDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLYKQRA 480
           VDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLYKQRA
Sbjct: 421 VDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLYKQRA 480

Query: 481 SRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARRTRRR 540
           SRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARRTRRR
Sbjct: 481 SRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARRTRRR 540

Query: 541 QAREQTGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGKVFEDVLESFYSIDCIKS 600
           QAREQTGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGKVFEDVLESFYSIDCIKS
Sbjct: 541 QAREQTGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGKVFEDVLESFYSIDCIKS 600

Query: 601 QFEAWRSKYYTSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFENMLWFESLLFYG 660
           QFEAWRSKYYTSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFENMLWFESLLFYG
Sbjct: 601 QFEAWRSKYYTSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFENMLWFESLLFYG 660

Query: 661 CEEREQEKDDVDVALLPTIVEKVILPKLTVIAENMWDPFSTTQTSRMVGITLKLINGYPS 720
           CEEREQEKDDVDVALLPTIVEKVILPKLTVIAENMWDPFSTTQTSRMVGITLKLINGYPS
Sbjct: 661 CEEREQEKDDVDVALLPTIVEKVILPKLTVIAENMWDPFSTTQTSRMVGITLKLINGYPS 720

Query: 721 VVNAENKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFWSSVKVI 780
           VVNAENKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFWSSVK++
Sbjct: 721 VVNAENKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFWSSVKLL 780


>gi|44890065 hypothetical protein LOC6936 [Homo sapiens]
          Length = 781

 Score =  333 bits (854), Expect = 4e-91
 Identities = 201/607 (33%), Positives = 346/607 (57%), Gaps = 50/607 (8%)

Query: 179 ISEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMAREL 238
           +S   ED++   SE ++++  +  + S++L    +    +IPDAAFI AAR+KR++AR  
Sbjct: 95  VSTDEEDKIHHSSESKDDQGLSSDS-SSSLGEKELSSTVKIPDAAFIQAARRKRELARAQ 153

Query: 239 GDFTPHD--NEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSD 296
            D+   D  +      + RE E+D   + DD EKR I F+++ ++ RQ++AEE      +
Sbjct: 154 DDYISLDVQHTSSISGMKRESEDDPESEPDDHEKR-IPFTLRPQTLRQRMAEES--ISRN 210

Query: 297 DDALVTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYS 356
           ++     ++DE+   WEQ+Q+RK + I + +     ++++                    
Sbjct: 211 EETSEESQEDEKQDTWEQQQMRKAVKIIEER-----DIDL-------------------- 245

Query: 357 YTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEKH 416
             + G+  +K +K D ++ F        PV ++++KKQL  RL  ++E H+++ +++EK+
Sbjct: 246 --SCGNGSSKVKKFDTSISFP-------PVNLEIIKKQLNTRLTLLQETHRSHLREYEKY 296

Query: 417 LQSRVDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECFSEKVPLINELESAIHQLY 476
           +Q    S   I+ LE SS       KF + M+ YV++L++C +EK+  I E+ES++H L 
Sbjct: 297 VQDVKSSKSTIQNLESSSNQ-ALNCKFYKSMKIYVENLIDCLNEKIINIQEIESSMHALL 355

Query: 477 KQRASRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRIAEREARR 536
            ++A   ++RRQD++K ES+     S K   + +  +F  D     E  +  + E E+RR
Sbjct: 356 LKQAMTFMKRRQDELKHESTYLQQLSRKDETSTS-GNFSVD-----EKTQWILEEIESRR 409

Query: 537 TRRRQAREQTGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGKVFEDVLESFYSID 596
           T+RRQAR  +G   +H EG SSDDE  S ++ +F   +  I ++  KVFE+V + F +I 
Sbjct: 410 TKRRQARVLSGN-CNHQEGTSSDDELPSAEMIDFQKSQGDILQKQKKVFEEVQDDFCNIQ 468

Query: 597 CIKSQFEAWRSKYYTSYKDAYIGLCLPKLFNPLIRLQLLTWTPLEAKCRDFENMLWFESL 656
            I  +F+ WR K+  SY +A+I LC+PKL NPLIR+QL+ W PL+ +    + M WF+S+
Sbjct: 469 NILLKFQQWREKFPDSYYEAFISLCIPKLLNPLIRVQLIDWNPLKLESTGLKEMPWFKSV 528

Query: 657 --LFYGCEEREQEKDDVDVALLPTIVEKVILPKLTVIAENMWDPFSTTQTSRMVGITLKL 714
                   E  +++   D  +L  I+ K I+P+LT   E +WDP ST+QT+ ++     +
Sbjct: 529 EEFMDSSVEDSKKESSSDKKVLSAIINKTIIPRLTDFVEFLWDPLSTSQTTSLITHCRVI 588

Query: 715 INGYPSVVNAENKNTQVYLKALLLRMRRTLDDDVFMPLYPKNVLENKNSGPYLFFQRQFW 774
           +  + +  N  +K+ Q  LK+++ RM++ ++DDVF+PLYPK+ +ENK S    F +RQFW
Sbjct: 589 LEEHSTCENEVSKSRQDLLKSIVSRMKKAVEDDVFIPLYPKSAVENKTSPHSKFQERQFW 648

Query: 775 SSVKVIK 781
           S +K+ +
Sbjct: 649 SGLKLFR 655



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 1  MFRKARRVNVRKRNDSEEEERERDEEQEP--PPLLPPPGTGEEAGPGGGDRA 50
          M  + +R   ++  DS + +   +   EP  P  LP PG+ EE  P GG RA
Sbjct: 1  MAHRPKRTFRQRAADSSDSDGAEESPAEPGAPRELPVPGSAEEEPPSGGGRA 52


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 137/656 (20%), Positives = 231/656 (35%), Gaps = 115/656 (17%)

Query: 2    FRKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLG--P 59
            FRK  R  + K ++  +E+ E+  +  P  L        E+   G DR    ES      
Sbjct: 905  FRKKDRDYLDKNSEKRKEQTEK-HKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRD 963

Query: 60   GPSPPSAL----TPGLGAEAGGGFPGGAEPGNGLKPRK-----RPRENKEVP-------- 102
            G + P           G E+G       + G GL+P +     R +E K+ P        
Sbjct: 964  GRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKT 1023

Query: 103  ---------------RASLLSFQDEEEENEEVFKVKKSSYSK-KIVKLLKKEYKEDLEKS 146
                             S+L    +++E ++ FK KK +  K K      KE K  L++ 
Sbjct: 1024 KPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQG 1083

Query: 147  KIKTE-----LNSSAESEQPLDKTGHVKDTNQEDGVIISEHGEDEMD------MESEKEE 195
            K K E     + S   SE+  DK G  K     D  I ++  ED+ D       +  +  
Sbjct: 1084 KEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIAD--IFTDESEDDRDSCMGSGFKMGEAS 1141

Query: 196  EKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHDNEPGKG---- 251
            + P+T G        L     G    A+  H     +Q      D  P D    +G    
Sbjct: 1142 DLPRTDG--------LQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADA 1193

Query: 252  -----RLVREDENDASDDED-----DDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALV 301
                   V E   +  D E      D + R  V S ++K  +QK+ E+   + + +D   
Sbjct: 1194 GRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDK-- 1251

Query: 302  TGEQDEELSRWEQEQIRKGINIPQVQAS-----QPAEVNMYYQNTYQTMPYGSSYGIPYS 356
               + +E S  E  + RK       + S     +   ++ Y +++   +   SS     S
Sbjct: 1252 AKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSS----DS 1307

Query: 357  YTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDRLDSMKELHKTNRQQHEK- 415
            +T  G     +   +  V F  P  +  P     + ++LK+     KE H+ +    +K 
Sbjct: 1308 FTDRGQEPGLTAFLE--VSFTEPPGDDKPRESACLPEKLKE-----KERHRHSSSSSKKS 1360

Query: 416  HLQSRVDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLEC------FSEKVPLINELE 469
            H + R    +A ++ +G     G   K   +   Y +D LE       ++ K  + +EL+
Sbjct: 1361 HDRERAKKEKAEKKEKGEDYKEGGSRK---DSGQYEKDFLEADAYGVSYNMKADIEDELD 1417

Query: 470  SAIHQLYKQRASRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRDRALYQEHAKRRI 529
              I          L    + D  D   E S    K      L  +G       +  K+R 
Sbjct: 1418 KTI---------ELFSTEKKDKNDSEREPSKKIEK-----ELKPYGSSAINILKEKKKRE 1463

Query: 530  AEREARRTRRRQAREQ--TGKMADHLEGLSSDDEETSTDITNFNLEKDRISKESGK 583
              RE  R  + + R++   G +  H + L     +     T       R+ K+  +
Sbjct: 1464 KHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQKPATRDKDSPPRVLKDKSR 1519



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 50/232 (21%), Positives = 98/232 (42%), Gaps = 49/232 (21%)

Query: 73  AEAGGGFPGGAEPGNGLKPRK--RPRENKEVPRASL----------LSFQDEEEENEEVF 120
           + A G  P   + G  +K  K     +NKE  + S+            ++D ++++++  
Sbjct: 613 SSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAI 672

Query: 121 KVKKSSYSKKIVKLLKKE---YKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGV 177
            ++    ++  +K+LK +   +K++ + SK+K E       ++   K   +KDTN++   
Sbjct: 673 LLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLK--RIKDTNKD--- 727

Query: 178 IISEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARE 237
            IS    +E D  ++ E+E+            SL    P E     +    +KK +    
Sbjct: 728 -ISRSFREEKDRSNKAEKER------------SLKEKSPKEEKLRLYKEERKKKSK---- 770

Query: 238 LGDFTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEE 289
                   + P K     E +ND  +D+   EK +I    KEK +++K+  E
Sbjct: 771 --------DRPSK----LEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYRE 810



 Score = 31.2 bits (69), Expect = 4.0
 Identities = 92/494 (18%), Positives = 179/494 (36%), Gaps = 69/494 (13%)

Query: 146 SKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIISEHGEDEMDMESEKEEEKPKTGGAFS 205
           S+ +  L   A++ +P   T  VKD  + D     +      D    K++ + +T    S
Sbjct: 321 SEFEKGLKHKAKNPEPQKATAPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETK---S 377

Query: 206 NALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHDNEP---GKGRLVR------- 255
           N+  S+  +   E+      +    K+   R L D +  ++     G G  +R       
Sbjct: 378 NSFISIPKM---EVKSYTKNNTIAPKKASHRILSDTSDEEDASVTVGTGEKLRLSAHTIL 434

Query: 256 --EDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEELSRWE 313
                 + S+ +   EK +    VK+K +++    E+   G   D   + E + E S   
Sbjct: 435 PGSKTREPSNAKQQKEKNK----VKKKRKKETKGREVRF-GKRSDKFCSSESESESSE-S 488

Query: 314 QEQIRKGINIPQVQASQPAEVN----MYYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQK 369
            E  R  +         P  +         +   T  +GSS     +  ++     K  +
Sbjct: 489 GEDDRDSLGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSSAAQKQN-PSHTDQHTKHWR 547

Query: 370 TDNTVPFKTPSNEMTPVTIDLVKKQLKDRLD---------SMKELHKTNRQQHEKHLQSR 420
           TDN     +P+        D  + +L    D         S+K + K  RQ+H K     
Sbjct: 548 TDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRK--RQEHRKRASLS 605

Query: 421 VDSTRAIERLEGS------SGGIGERYKF-------------------LQEMRGYVQDLL 455
              +  +   EG+       G + +++K                    L+      +D  
Sbjct: 606 EKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSK 665

Query: 456 ECFSEKVPLINEL--ESAIHQLYKQRASRLVQRRQDDIKDESSEFSSHSNKALMAPNLDS 513
           +   + + L N+L  E+ +  L   R     + +   +K E  E+     K+L      +
Sbjct: 666 QKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTN 725

Query: 514 FGRDRALYQEHAKRRIAEREARRTRRRQAREQTGKMADHLEGLSSDDEETSTDITNFNLE 573
               R+  +E  +   AE+E R  + +  +E+  ++        S D  +  +  N +L+
Sbjct: 726 KDISRSFREEKDRSNKAEKE-RSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKN-DLK 783

Query: 574 KDRISKESGKVFED 587
           +D+ISKE  K+F++
Sbjct: 784 EDKISKEKEKIFKE 797


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 26/55 (47%), Positives = 27/55 (49%), Gaps = 10/55 (18%)

Query: 34 PPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPGLGAEAGGGFPGGAEPGNG 88
          PPPG    AG GGG    GG    GP P PP A       + GGG PGG  PG G
Sbjct: 9  PPPGPPPPAGGGGGAGGAGG----GPPPGPPGA------GDRGGGGPGGGGPGGG 53



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 31/102 (30%), Positives = 41/102 (40%), Gaps = 21/102 (20%)

Query: 29  PPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPG---------------LGA 73
           PPP   PPG G+  G G G   PGG S  GP   PP    PG               + A
Sbjct: 30  PPP--GPPGAGDRGGGGPGGGGPGGGSAGGPS-QPPGGGGPGIRKDAFADAVQRARQIAA 86

Query: 74  EAGGGFP---GGAEPGNGLKPRKRPRENKEVPRASLLSFQDE 112
           + GG        + P  G   +KR  E+ + P +  L+ Q +
Sbjct: 87  KIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGD 128


>gi|33946313 ninein isoform 4 [Homo sapiens]
          Length = 2096

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 69/327 (21%), Positives = 130/327 (39%), Gaps = 35/327 (10%)

Query: 230  KKRQMARELGDFTPHDNEPGKGRLVREDENDAS---DDEDDDEKRRIVFSVKEKSQRQ-- 284
            K  ++A   G    H   P     V  +EN       D+    +  I     EK++ Q  
Sbjct: 1411 KAHEIAWLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQEL 1470

Query: 285  --KIAEEIGIEGSDDDALVTGEQDEELSRWEQE------QIRKGINIPQVQASQPAEVNM 336
              K+ E + I     D L  GE++EEL     +      ++++ + + + ++ +  + N 
Sbjct: 1471 TRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENS 1530

Query: 337  YYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLK 396
              +N   T+    S       T  GS +   QKT+         N      ++ +KKQ+ 
Sbjct: 1531 ILRNEITTLNEEDSISNLKLGTLNGSQEEMWQKTETV----KQENAAVQKMVENLKKQIS 1586

Query: 397  D------RLD-SMKELHKTNRQQHEK--HLQSRVDSTRAIERLEGSSGGIGERYKFLQEM 447
            +      +LD    EL + N Q  EK   L  R+      +  E  +  + ER    QE 
Sbjct: 1587 ELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEERE---QEK 1643

Query: 448  RGYVQDLLECFSEKVPLINELESAIHQLYKQRASRLVQRRQDDIKDESSEFSSHSNKALM 507
                ++L  C  +   L++ LE+ + ++  Q  + +VQ+    +KDE  +      +   
Sbjct: 1644 FNLKEELERCKVQSSTLVSSLEAELSEVKIQ--THIVQQENHLLKDELEKM----KQLHR 1697

Query: 508  APNLDSFGRDRALYQEHAKRRIAEREA 534
             P+L  F +  +    + ++ + E+EA
Sbjct: 1698 CPDLSDFQQKISSVLSYNEKLLKEKEA 1724


>gi|33946321 ninein isoform 5 [Homo sapiens]
          Length = 2090

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 69/327 (21%), Positives = 130/327 (39%), Gaps = 35/327 (10%)

Query: 230  KKRQMARELGDFTPHDNEPGKGRLVREDENDAS---DDEDDDEKRRIVFSVKEKSQRQ-- 284
            K  ++A   G    H   P     V  +EN       D+    +  I     EK++ Q  
Sbjct: 1405 KAHEIAWLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQEL 1464

Query: 285  --KIAEEIGIEGSDDDALVTGEQDEELSRWEQE------QIRKGINIPQVQASQPAEVNM 336
              K+ E + I     D L  GE++EEL     +      ++++ + + + ++ +  + N 
Sbjct: 1465 TRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENS 1524

Query: 337  YYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLK 396
              +N   T+    S       T  GS +   QKT+         N      ++ +KKQ+ 
Sbjct: 1525 ILRNEITTLNEEDSISNLKLGTLNGSQEEMWQKTETV----KQENAAVQKMVENLKKQIS 1580

Query: 397  D------RLD-SMKELHKTNRQQHEK--HLQSRVDSTRAIERLEGSSGGIGERYKFLQEM 447
            +      +LD    EL + N Q  EK   L  R+      +  E  +  + ER    QE 
Sbjct: 1581 ELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEERE---QEK 1637

Query: 448  RGYVQDLLECFSEKVPLINELESAIHQLYKQRASRLVQRRQDDIKDESSEFSSHSNKALM 507
                ++L  C  +   L++ LE+ + ++  Q  + +VQ+    +KDE  +      +   
Sbjct: 1638 FNLKEELERCKVQSSTLVSSLEAELSEVKIQ--THIVQQENHLLKDELEKM----KQLHR 1691

Query: 508  APNLDSFGRDRALYQEHAKRRIAEREA 534
             P+L  F +  +    + ++ + E+EA
Sbjct: 1692 CPDLSDFQQKISSVLSYNEKLLKEKEA 1718


>gi|148536871 ninein isoform 1 [Homo sapiens]
          Length = 2046

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 69/327 (21%), Positives = 130/327 (39%), Gaps = 35/327 (10%)

Query: 230  KKRQMARELGDFTPHDNEPGKGRLVREDENDAS---DDEDDDEKRRIVFSVKEKSQRQ-- 284
            K  ++A   G    H   P     V  +EN       D+    +  I     EK++ Q  
Sbjct: 1405 KAHEIAWLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQEL 1464

Query: 285  --KIAEEIGIEGSDDDALVTGEQDEELSRWEQE------QIRKGINIPQVQASQPAEVNM 336
              K+ E + I     D L  GE++EEL     +      ++++ + + + ++ +  + N 
Sbjct: 1465 TRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENS 1524

Query: 337  YYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLK 396
              +N   T+    S       T  GS +   QKT+         N      ++ +KKQ+ 
Sbjct: 1525 ILRNEITTLNEEDSISNLKLGTLNGSQEEMWQKTETV----KQENAAVQKMVENLKKQIS 1580

Query: 397  D------RLD-SMKELHKTNRQQHEK--HLQSRVDSTRAIERLEGSSGGIGERYKFLQEM 447
            +      +LD    EL + N Q  EK   L  R+      +  E  +  + ER    QE 
Sbjct: 1581 ELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEERE---QEK 1637

Query: 448  RGYVQDLLECFSEKVPLINELESAIHQLYKQRASRLVQRRQDDIKDESSEFSSHSNKALM 507
                ++L  C  +   L++ LE+ + ++  Q  + +VQ+    +KDE  +      +   
Sbjct: 1638 FNLKEELERCKVQSSTLVSSLEAELSEVKIQ--THIVQQENHLLKDELEKM----KQLHR 1691

Query: 508  APNLDSFGRDRALYQEHAKRRIAEREA 534
             P+L  F +  +    + ++ + E+EA
Sbjct: 1692 CPDLSDFQQKISSVLSYNEKLLKEKEA 1718


>gi|148536869 ninein isoform 2 [Homo sapiens]
          Length = 2133

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 69/327 (21%), Positives = 130/327 (39%), Gaps = 35/327 (10%)

Query: 230  KKRQMARELGDFTPHDNEPGKGRLVREDENDAS---DDEDDDEKRRIVFSVKEKSQRQ-- 284
            K  ++A   G    H   P     V  +EN       D+    +  I     EK++ Q  
Sbjct: 1405 KAHEIAWLHGTIQTHQERPRVQNQVILEENTTLLGFQDKHFQHQATIAELELEKTKLQEL 1464

Query: 285  --KIAEEIGIEGSDDDALVTGEQDEELSRWEQE------QIRKGINIPQVQASQPAEVNM 336
              K+ E + I     D L  GE++EEL     +      ++++ + + + ++ +  + N 
Sbjct: 1465 TRKLKERVTILVKQKDVLSHGEKEEELKAMMHDLQITCSEMQQKVELLRYESEKLQQENS 1524

Query: 337  YYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLK 396
              +N   T+    S       T  GS +   QKT+         N      ++ +KKQ+ 
Sbjct: 1525 ILRNEITTLNEEDSISNLKLGTLNGSQEEMWQKTETV----KQENAAVQKMVENLKKQIS 1580

Query: 397  D------RLD-SMKELHKTNRQQHEK--HLQSRVDSTRAIERLEGSSGGIGERYKFLQEM 447
            +      +LD    EL + N Q  EK   L  R+      +  E  +  + ER    QE 
Sbjct: 1581 ELKIKNQQLDLENTELSQKNSQNQEKLQELNQRLTEMLCQKEKEPGNSALEERE---QEK 1637

Query: 448  RGYVQDLLECFSEKVPLINELESAIHQLYKQRASRLVQRRQDDIKDESSEFSSHSNKALM 507
                ++L  C  +   L++ LE+ + ++  Q  + +VQ+    +KDE  +      +   
Sbjct: 1638 FNLKEELERCKVQSSTLVSSLEAELSEVKIQ--THIVQQENHLLKDELEKM----KQLHR 1691

Query: 508  APNLDSFGRDRALYQEHAKRRIAEREA 534
             P+L  F +  +    + ++ + E+EA
Sbjct: 1692 CPDLSDFQQKISSVLSYNEKLLKEKEA 1718


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
            sapiens]
          Length = 1870

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 86/412 (20%), Positives = 163/412 (39%), Gaps = 49/412 (11%)

Query: 86   GNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEK 145
            GN  K  K   +   + + S +  ++ E+EN+E+  VK+++   K +  L+    EDL  
Sbjct: 860  GNLEKENKTLSKEIGIYKESCVRLKELEKENKEL--VKRATIDIKTLVTLR----EDLVS 913

Query: 146  SKIKTE-LNSSAES-EQPLDKTG-------HVKDTNQEDGVIISEHGEDEMDMESEKEEE 196
             K+KT+ +N+  E     L+K G       H + +  +   ++    E  +    E +EE
Sbjct: 914  EKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEE 973

Query: 197  KPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHDNEPGKGRLVRE 256
            K     A     ++ N     E+      + A K+RQ    +   +P    P  G     
Sbjct: 974  KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP----PISGE---- 1025

Query: 257  DENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEELSRWEQEQ 316
               D   + +  E  R +  VK++           IE   ++A +  E+    ++ +Q +
Sbjct: 1026 ---DNKWERESQETTRELLKVKDRL----------IEVERNNATLQAEKQALKTQLKQLE 1072

Query: 317  IRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPF 376
             +      Q+ A Q   V++  QNT       +   +  S     S+   +Q     +  
Sbjct: 1073 TQNNNLQAQILALQRQTVSLQEQNT-TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQ 1131

Query: 377  KTPSNEMTPVTIDLVKKQLKDRLDSMKE-------LHKTNRQQHEKHLQSRVDSTRAIER 429
             +  NE   V  +  ++ LK   DS+ +       LH+    ++E  +        A + 
Sbjct: 1132 SSLENENESVIKE--REDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKN 1189

Query: 430  LEGSSGGIGERYKFLQEMRGYVQDL---LECFSEKVPLINELESAIHQLYKQ 478
            LE     + +RY  L + +G ++DL   L+   EK+ L N+    +   YK+
Sbjct: 1190 LEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKK 1241



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 91/496 (18%), Positives = 195/496 (39%), Gaps = 93/496 (18%)

Query: 110  QDEEEENEEVFK-VKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESE-QPLDKTGH 167
            +D E+EN+ + + +K++S     ++  K++ K++LE  K K E     E+E   L+K   
Sbjct: 583  KDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENE 642

Query: 168  VKDTNQEDGVIISEHGE--DEMDMESEKEEEK-PKTGGAFSNALSSLNVLRPGEIPDAAF 224
            +      +  I  E  E  ++ + E E+E  K  KT  +F N    L  L          
Sbjct: 643  LLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESL---------- 692

Query: 225  IHAARKKRQMARELGDFTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQ 284
                                            ++ ++  DE++ E RR V S+K  S + 
Sbjct: 693  --------------------------------EKENSQLDEENLELRRNVESLKCASMKM 720

Query: 285  KIAEEIGIEGSDDDALVTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQ----- 339
                ++ +E  + ++             E+EQ++KG+ + +    +   + + YQ     
Sbjct: 721  A---QLQLENKELES-------------EKEQLKKGLELLKASFKKTERLEVSYQGLDIE 764

Query: 340  -NTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDR 398
                Q     S+  I    +     + ++Q    T+       +++   ++ ++K+ K  
Sbjct: 765  NQRLQKTLENSNKKIQQLESELQDLEMENQ----TLQKNLEELKISSKRLEQLEKENKSL 820

Query: 399  LDSMKELHKTNRQQHEKHLQSRVDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECF 458
                 +L K  +Q  +++ + R  +      LE ++  IG     L++    +   +  +
Sbjct: 821  EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN----LEKENKTLSKEIGIY 876

Query: 459  SEKVPLINELESAIHQLYKQRA---SRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFG 515
             E    + ELE    +L K+       LV  R+D + ++      +++   +   L+  G
Sbjct: 877  KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG 936

Query: 516  --RDRALYQEHA---KRRIAEREARRTRRRQAREQTGKMADHLEGLSSDDEETSTDITNF 570
              ++R L+ E +   + ++ E +   T ++    +  K+A     L +  EE+    TN+
Sbjct: 937  LNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIA----ALEARLEES----TNY 988

Query: 571  NLEKDRISKESGKVFE 586
            N +  +  K   K +E
Sbjct: 989  NQQLRQELKTVKKNYE 1004



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 64/297 (21%), Positives = 125/297 (42%), Gaps = 58/297 (19%)

Query: 265 EDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEELSRW----EQEQIRKG 320
           E D ++++I     E+   + +  E+  + S D++L  G + E++SR     E  Q   G
Sbjct: 397 ERDMDRKKI-----EELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLG 451

Query: 321 INIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPFKTP- 379
             + ++ +S+  ++ M  Q+  +T+    +     S     S   K +K +  +  K   
Sbjct: 452 HEVNELTSSRLLKLEMENQSLTKTVEELRT--TVDSVEGNASKILKMEKENQRLSKKVEI 509

Query: 380 -SNEMTP----------VTIDLVKK--QLKDRLDSMKELHKTN---RQQHEKHLQSRVDS 423
             NE+            ++ DL+K+  QL+  +++++E  +      +Q  +HL   V S
Sbjct: 510 LENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569

Query: 424 TRAIERL--EGSSGGIGERYKFLQEM--------------RGYVQDLLECFSEKVPLINE 467
            R   ++  E     I +  K L E               +  ++  LE + EK     E
Sbjct: 570 LRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE 629

Query: 468 LESAIHQLYKQRASRLVQRRQDDIK----------DESSEFSSHSNKALMAPNLDSF 514
           LE+ +H L K+  + L+Q++  ++K           E+SE    + K  +   LDSF
Sbjct: 630 LENELHHLEKE--NELLQKKITNLKITCEKIEALEQENSELERENRK--LKKTLDSF 682


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 63/316 (19%), Positives = 118/316 (37%), Gaps = 58/316 (18%)

Query: 12   KRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPGL 71
            KR   +EEE E  ++ +  P+L P     +               +   P  P   TP  
Sbjct: 1101 KRKSKDEEEDEESDDADDTPILKPVSLLRKRD-------------VKNSPLEPDTSTP-- 1145

Query: 72   GAEAGGGFPGGAEPGNGLKP---RKRPRENKEVPRA-SLLSFQDEEEENEEVFKVKKSSY 127
              +   G+P     G   KP   +KRP        +  ++    +    E +  + K+  
Sbjct: 1146 -LKKKKGWP----KGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200

Query: 128  SKKIVKLLKK-EYKEDL-------EKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVII 179
              KI +  +  E KED+       E+ +++ E   + E E+    +  V   +  D    
Sbjct: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260

Query: 180  SEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELG 239
             E   +  + E E+EEEKP+                             R+  +  +EL 
Sbjct: 1261 PE--TETKEPEVEEEEEKPRVS------------------------EEQRQSEEEQQELE 1294

Query: 240  DFTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDA 299
            +  P + E       + D++DA D++D   +      ++E+  R+ + EE G++ S  DA
Sbjct: 1295 EPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDA 1354

Query: 300  LVTGEQDEELSRWEQE 315
             +   +++   + E E
Sbjct: 1355 NMQKSREKIKDKEETE 1370



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 40/130 (30%), Positives = 56/130 (43%), Gaps = 13/130 (10%)

Query: 95   PRENKEVPRASLLSFQDEEEENEEVFKVKKSS---YSKKIVKLLKKEYKEDLEKSKIKTE 151
            PR   E  RA L  F +  EE EE    + SS    +K  +K  KK +     + + +  
Sbjct: 970  PRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKR-KKPFLHRRRRVRKRKH 1028

Query: 152  LNSSAESEQPLDKTGHVKDTNQEDGVIISEHGED------EMDMESEKEEEKPKTGGAFS 205
             NSS  +E  + +T  V D   ED    SE          E+D E E+E+E       + 
Sbjct: 1029 HNSSVVTET-ISETTEVLDEPFEDSD--SERPMPRLEPTFEIDEEEEEEDENELFPREYF 1085

Query: 206  NALSSLNVLR 215
              LSS +VLR
Sbjct: 1086 RRLSSQDVLR 1095


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 63/316 (19%), Positives = 118/316 (37%), Gaps = 58/316 (18%)

Query: 12   KRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPGL 71
            KR   +EEE E  ++ +  P+L P     +               +   P  P   TP  
Sbjct: 1101 KRKSKDEEEDEESDDADDTPILKPVSLLRKRD-------------VKNSPLEPDTSTP-- 1145

Query: 72   GAEAGGGFPGGAEPGNGLKP---RKRPRENKEVPRA-SLLSFQDEEEENEEVFKVKKSSY 127
              +   G+P     G   KP   +KRP        +  ++    +    E +  + K+  
Sbjct: 1146 -LKKKKGWP----KGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200

Query: 128  SKKIVKLLKK-EYKEDL-------EKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVII 179
              KI +  +  E KED+       E+ +++ E   + E E+    +  V   +  D    
Sbjct: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260

Query: 180  SEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELG 239
             E   +  + E E+EEEKP+                             R+  +  +EL 
Sbjct: 1261 PE--TETKEPEVEEEEEKPRVS------------------------EEQRQSEEEQQELE 1294

Query: 240  DFTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDA 299
            +  P + E       + D++DA D++D   +      ++E+  R+ + EE G++ S  DA
Sbjct: 1295 EPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDA 1354

Query: 300  LVTGEQDEELSRWEQE 315
             +   +++   + E E
Sbjct: 1355 NMQKSREKIKDKEETE 1370



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 40/130 (30%), Positives = 56/130 (43%), Gaps = 13/130 (10%)

Query: 95   PRENKEVPRASLLSFQDEEEENEEVFKVKKSS---YSKKIVKLLKKEYKEDLEKSKIKTE 151
            PR   E  RA L  F +  EE EE    + SS    +K  +K  KK +     + + +  
Sbjct: 970  PRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKR-KKPFLHRRRRVRKRKH 1028

Query: 152  LNSSAESEQPLDKTGHVKDTNQEDGVIISEHGED------EMDMESEKEEEKPKTGGAFS 205
             NSS  +E  + +T  V D   ED    SE          E+D E E+E+E       + 
Sbjct: 1029 HNSSVVTET-ISETTEVLDEPFEDSD--SERPMPRLEPTFEIDEEEEEEDENELFPREYF 1085

Query: 206  NALSSLNVLR 215
              LSS +VLR
Sbjct: 1086 RRLSSQDVLR 1095


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 63/316 (19%), Positives = 118/316 (37%), Gaps = 58/316 (18%)

Query: 12   KRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPGL 71
            KR   +EEE E  ++ +  P+L P     +               +   P  P   TP  
Sbjct: 1101 KRKSKDEEEDEESDDADDTPILKPVSLLRKRD-------------VKNSPLEPDTSTP-- 1145

Query: 72   GAEAGGGFPGGAEPGNGLKP---RKRPRENKEVPRA-SLLSFQDEEEENEEVFKVKKSSY 127
              +   G+P     G   KP   +KRP        +  ++    +    E +  + K+  
Sbjct: 1146 -LKKKKGWP----KGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGR 1200

Query: 128  SKKIVKLLKK-EYKEDL-------EKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVII 179
              KI +  +  E KED+       E+ +++ E   + E E+    +  V   +  D    
Sbjct: 1201 KPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNS 1260

Query: 180  SEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELG 239
             E   +  + E E+EEEKP+                             R+  +  +EL 
Sbjct: 1261 PE--TETKEPEVEEEEEKPRVS------------------------EEQRQSEEEQQELE 1294

Query: 240  DFTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDA 299
            +  P + E       + D++DA D++D   +      ++E+  R+ + EE G++ S  DA
Sbjct: 1295 EPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQESFLDA 1354

Query: 300  LVTGEQDEELSRWEQE 315
             +   +++   + E E
Sbjct: 1355 NMQKSREKIKDKEETE 1370



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 40/130 (30%), Positives = 56/130 (43%), Gaps = 13/130 (10%)

Query: 95   PRENKEVPRASLLSFQDEEEENEEVFKVKKSS---YSKKIVKLLKKEYKEDLEKSKIKTE 151
            PR   E  RA L  F +  EE EE    + SS    +K  +K  KK +     + + +  
Sbjct: 970  PRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKR-KKPFLHRRRRVRKRKH 1028

Query: 152  LNSSAESEQPLDKTGHVKDTNQEDGVIISEHGED------EMDMESEKEEEKPKTGGAFS 205
             NSS  +E  + +T  V D   ED    SE          E+D E E+E+E       + 
Sbjct: 1029 HNSSVVTET-ISETTEVLDEPFEDSD--SERPMPRLEPTFEIDEEEEEEDENELFPREYF 1085

Query: 206  NALSSLNVLR 215
              LSS +VLR
Sbjct: 1086 RRLSSQDVLR 1095


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 44/198 (22%), Positives = 76/198 (38%), Gaps = 25/198 (12%)

Query: 12  KRNDSEEEERER-----DEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSA 66
           +  D EEEE +      DE++EPP   P    G+ A P      P   + +     P ++
Sbjct: 75  EEEDEEEEEEDEEALLEDEDEEPP---PAQALGQAAQP---PPEPPEAAAMEAAAEPDAS 128

Query: 67  LTPGLGAEAGGGFPGGAEPGNGLKPRKRPRE-------NKEVPRASLLSFQDEEEENEEV 119
             P       GG  GG E G G +    P E         EVP       Q +++++E+ 
Sbjct: 129 EKPAEATAGSGGVNGGEEQGLGKREEDEPEERSGDETPGSEVPGDKAAEEQGDDQDSEK- 187

Query: 120 FKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSA---ESEQPLDKTGHVKDTNQEDG 176
               K + S    + +K++  E  E  +   E    A    S+ PL      KD  ++  
Sbjct: 188 ---SKPAGSDGERRGVKRQRDEKDEHGRAYYEFREEAYHSRSKSPLPPEEEAKDEEEDQT 244

Query: 177 VIISEHGEDEMDMESEKE 194
           ++  +    ++  +  K+
Sbjct: 245 LVNLDTYTSDLHFQVSKD 262


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 23/59 (38%), Positives = 26/59 (44%), Gaps = 2/59 (3%)

Query: 30  PPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPGLGAEAGGGFPGGAEPGNG 88
           PP  PP        P  G   P   ++ GPGP P     PG G   GG  PGG +PG G
Sbjct: 165 PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQG--PGPGGPKGGKMPGGPKPGGG 221



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 33/102 (32%), Positives = 43/102 (42%), Gaps = 10/102 (9%)

Query: 29  PPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPGLGAEAGGGFP---GGAEP 85
           PP  +P PG G + GPG G   P G  + G GP P     PGL    G   P   GG EP
Sbjct: 187 PPAAVPGPGPGPKQGPGPG--GPKGGKMPG-GPKPGGG--PGLSTPGGHPKPPHRGGGEP 241

Query: 86  GNGLK--PRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKS 125
             G +  P    + ++  P        +E+  + E FK   S
Sbjct: 242 RGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLS 283



 Score = 37.0 bits (84), Expect = 0.074
 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 4/71 (5%)

Query: 29  PPPLLPPPGTGEEAGPGGGDRAPGGESLLGPG---PSPPSALTPGLGAEAGG-GFPGGAE 84
           PP   P  G    +GPG     P   +   PG   P+PPS+  P    +AGG   P  A 
Sbjct: 132 PPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAV 191

Query: 85  PGNGLKPRKRP 95
           PG G  P++ P
Sbjct: 192 PGPGPGPKQGP 202



 Score = 33.5 bits (75), Expect = 0.81
 Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 10/87 (11%)

Query: 19  EERERDEEQEPPPLLPPPGT--------GEEAGPGGGDRAPGGESLLGPGPSPPSALTPG 70
           +++++   Q+PPP  PPP           ++  P     +       GPGP+P     P 
Sbjct: 67  QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP 126

Query: 71  LGAEAGGGFP--GGAEPGNGLKPRKRP 95
             + A    P   GA PG+G  P   P
Sbjct: 127 ASSSAPPATPPTSGAPPGSGPGPTPTP 153



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 1/85 (1%)

Query: 3   RKARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPS 62
           R+   + +R+R   E+  R+R+E       + P       G GGG    G     G    
Sbjct: 573 RREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMG-GGGAMNMGDPYGSGGQKF 631

Query: 63  PPSALTPGLGAEAGGGFPGGAEPGN 87
           PP     G+G EA  G P     G+
Sbjct: 632 PPLGGGGGIGYEANPGVPPATMSGS 656


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
            sapiens]
          Length = 1843

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 87/413 (21%), Positives = 163/413 (39%), Gaps = 50/413 (12%)

Query: 86   GNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEK 145
            GN  K  K   +   + + S +  ++ E+EN+E+  VK+++   K +  L+    EDL  
Sbjct: 860  GNLEKENKTLSKEIGIYKESCVRLKELEKENKEL--VKRATIDIKTLVTLR----EDLVS 913

Query: 146  SKIKTE-LNSSAES-EQPLDKTGHVKD--------TNQEDGVIISEHGEDEMDMESEKEE 195
             K+KT+ +N+  E     L+K G  K+        T+     ++    E  +    E +E
Sbjct: 914  EKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKE 973

Query: 196  EKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHDNEPGKGRLVR 255
            EK     A     ++ N     E+      + A K+RQ    +   +P    P  G    
Sbjct: 974  EKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP----PISGE--- 1026

Query: 256  EDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEELSRWEQE 315
                D   + +  E  R +  VK++           IE   ++A +  E+    ++ +Q 
Sbjct: 1027 ----DNKWERESQETTRELLKVKDRL----------IEVERNNATLQAEKQALKTQLKQL 1072

Query: 316  QIRKGINIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVP 375
            + +      Q+ A Q   V++  QNT       +   +  S     S+   +Q     + 
Sbjct: 1073 ETQNNNLQAQILALQRQTVSLQEQNT-TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1131

Query: 376  FKTPSNEMTPVTIDLVKKQLKDRLDSMKE-------LHKTNRQQHEKHLQSRVDSTRAIE 428
              +  NE   V  +  ++ LK   DS+ +       LH+    ++E  +        A +
Sbjct: 1132 QSSLENENESVIKE--REDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHK 1189

Query: 429  RLEGSSGGIGERYKFLQEMRGYVQDL---LECFSEKVPLINELESAIHQLYKQ 478
             LE     + +RY  L + +G ++DL   L+   EK+ L N+    +   YK+
Sbjct: 1190 NLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKK 1242



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 91/497 (18%), Positives = 195/497 (39%), Gaps = 94/497 (18%)

Query: 110  QDEEEENEEVFK-VKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESE-QPLDKTGH 167
            +D E+EN+ + + +K++S     ++  K++ K++LE  K K E     E+E   L+K   
Sbjct: 583  KDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENE 642

Query: 168  VKDTNQEDGVIISEHGE--DEMDMESEKEEEK-PKTGGAFSNALSSLNVLRPGEIPDAAF 224
            +      +  I  E  E  ++ + E E+E  K  KT  +F N    L  L          
Sbjct: 643  LLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESL---------- 692

Query: 225  IHAARKKRQMARELGDFTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQ 284
                                            ++ ++  DE++ E RR V S+K  S + 
Sbjct: 693  --------------------------------EKENSQLDEENLELRRNVESLKCASMKM 720

Query: 285  KIAEEIGIEGSDDDALVTGEQDEELSRWEQEQIRKGINIPQVQASQPAEVNMYYQ----- 339
                ++ +E  + ++             E+EQ++KG+ + +    +   + + YQ     
Sbjct: 721  A---QLQLENKELES-------------EKEQLKKGLELLKASFKKTERLEVSYQGLDIE 764

Query: 340  -NTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPFKTPSNEMTPVTIDLVKKQLKDR 398
                Q     S+  I    +     + ++Q    T+       +++   ++ ++K+ K  
Sbjct: 765  NQRLQKTLENSNKKIQQLESELQDLEMENQ----TLQKNLEELKISSKRLEQLEKENKSL 820

Query: 399  LDSMKELHKTNRQQHEKHLQSRVDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDLLECF 458
                 +L K  +Q  +++ + R  +      LE ++  IG     L++    +   +  +
Sbjct: 821  EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN----LEKENKTLSKEIGIY 876

Query: 459  SEKVPLINELESAIHQLYKQRA---SRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFG 515
             E    + ELE    +L K+       LV  R+D + ++      +++   +   L+  G
Sbjct: 877  KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG 936

Query: 516  --RDRALYQEH----AKRRIAEREARRTRRRQAREQTGKMADHLEGLSSDDEETSTDITN 569
              ++R L+ E     ++ ++ E +   T ++    +  K+A     L +  EE+    TN
Sbjct: 937  LNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIA----ALEARLEES----TN 988

Query: 570  FNLEKDRISKESGKVFE 586
            +N +  +  K   K +E
Sbjct: 989  YNQQLRQELKTVKKNYE 1005



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 64/297 (21%), Positives = 125/297 (42%), Gaps = 58/297 (19%)

Query: 265 EDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEELSRW----EQEQIRKG 320
           E D ++++I     E+   + +  E+  + S D++L  G + E++SR     E  Q   G
Sbjct: 397 ERDMDRKKI-----EELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLG 451

Query: 321 INIPQVQASQPAEVNMYYQNTYQTMPYGSSYGIPYSYTAYGSSDAKSQKTDNTVPFKTP- 379
             + ++ +S+  ++ M  Q+  +T+    +     S     S   K +K +  +  K   
Sbjct: 452 HEVNELTSSRLLKLEMENQSLTKTVEELRT--TVDSVEGNASKILKMEKENQRLSKKVEI 509

Query: 380 -SNEMTP----------VTIDLVKK--QLKDRLDSMKELHKTN---RQQHEKHLQSRVDS 423
             NE+            ++ DL+K+  QL+  +++++E  +      +Q  +HL   V S
Sbjct: 510 LENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569

Query: 424 TRAIERL--EGSSGGIGERYKFLQEM--------------RGYVQDLLECFSEKVPLINE 467
            R   ++  E     I +  K L E               +  ++  LE + EK     E
Sbjct: 570 LRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE 629

Query: 468 LESAIHQLYKQRASRLVQRRQDDIK----------DESSEFSSHSNKALMAPNLDSF 514
           LE+ +H L K+  + L+Q++  ++K           E+SE    + K  +   LDSF
Sbjct: 630 LENELHHLEKE--NELLQKKITNLKITCEKIEALEQENSELERENRK--LKKTLDSF 682


>gi|32171221 GRP1 (general receptor for phosphoinositides
           1)-associated scaffold protein [Homo sapiens]
          Length = 395

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 39/111 (35%), Positives = 48/111 (43%), Gaps = 27/111 (24%)

Query: 26  EQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALT-------PGLGAEAGGG 78
           + EPP L PPP      GPG     P     +GPGP P +AL+        G G   GGG
Sbjct: 292 DSEPPALPPPPPPARAFGPG-----PAETPAVGPGPGPRAALSRSASVRCAGPGGGGGGG 346

Query: 79  FPGG--------AEPGNGLKPRK----RPRENKEVPRASLLSFQDEEEENE 117
            PG         A  G GL+  K    R R  K +P    L+   EEEE++
Sbjct: 347 APGALWTEAREQALCGPGLRKTKYRSFRRRLLKFIPG---LNRSLEEEESQ 394


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 68/281 (24%), Positives = 104/281 (37%), Gaps = 13/281 (4%)

Query: 4    KARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSP 63
            K  R    +  + EEEE E +EE+         G GEE G  G     G E   G G   
Sbjct: 823  KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE---GEGEGE 879

Query: 64   PSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKVK 123
                  G G E G G  G  E G G    +   E +E         ++E EE E   + +
Sbjct: 880  EEE-GEGEGEEEGEG-EGEEEEGEGEGEEEGEGEGEEEEGEG--KGEEEGEEGEGEGEEE 935

Query: 124  KSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIISEHG 183
            +     +  +   +E + + E  + + E     E E   ++     +  + +G    E G
Sbjct: 936  EGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEG 995

Query: 184  EDEMDMESEKEEEKPKTG-----GAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARE- 237
            E+E + E E EEE    G     G     +        GE  +       R+K     E 
Sbjct: 996  EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055

Query: 238  LGDFTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVK 278
              +    + E GK +   E+EN+  D E+  +  +I  SVK
Sbjct: 1056 RRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVK 1096



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 59/234 (25%), Positives = 92/234 (39%), Gaps = 33/234 (14%)

Query: 109 FQDEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHV 168
           +QDEE E  E  K +        ++   +  KE  EK + K       E EQ   + GH 
Sbjct: 669 WQDEEREKGEKDKGRGE------MERPGEGEKELAEKEEWKKR--DGEEQEQKEREQGHQ 720

Query: 169 KDTNQE-DGVIISEHGEDEMDMESEKEEEKPKTG-GAFSNALSSLNVLRPGEIPDAAFIH 226
           K+ NQE +     EHGE E + E ++EEE+ K G G        +   R  E  +     
Sbjct: 721 KERNQEMEEGGEEEHGEGEEE-EGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779

Query: 227 AARKKR--------------------QMARELGDFTPHDNEPGKGRLVREDENDASDDED 266
            A K+                     +   E G+    + E GKG   RE+E +  + E+
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGE--REEEEEEGEGEE 837

Query: 267 DDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEELSRWEQEQIRKG 320
           ++ +        E+ + +   EE G EG  ++    GE + E    E E   +G
Sbjct: 838 EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG 891



 Score = 37.0 bits (84), Expect = 0.074
 Identities = 45/158 (28%), Positives = 65/158 (41%), Gaps = 16/158 (10%)

Query: 15   DSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPGLGAE 74
            + EEEE E + E+E        G GEE G G G+    GE + G           G G E
Sbjct: 989  EGEEEEGEEEGEEE--------GEGEEEGEGEGEEEEEGE-VEGEVEGEEG---EGEGEE 1036

Query: 75   AGGGFPGGAEPGNGL-KPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYSKKIVK 133
              G   G      G  +  +R RE +E          +EE E ++  + KK S  K  VK
Sbjct: 1037 EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVK 1096

Query: 134  LLKKEYKEDLEKSKIKTELNSSAE-SEQPLDKTGHVKD 170
              K  +K   +KS   T+ N   + S+ P+     +K+
Sbjct: 1097 YGK--HKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKN 1132



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 68/315 (21%), Positives = 115/315 (36%), Gaps = 55/315 (17%)

Query: 5   ARRVNVRKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPP 64
           A +   +KR+  E+E++ER++  +           +E   GG +    GE     G    
Sbjct: 697 AEKEEWKKRDGEEQEQKEREQGHQKE-------RNQEMEEGGEEEHGEGEE--EEGDREE 747

Query: 65  SALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKK 124
                G G E G G     E   G +  K   E K+  RA       +EE+ EE     +
Sbjct: 748 EEEKEGEGKEEGEG-----EEVEG-EREKEEGERKKEERAG------KEEKGEEEGDQGE 795

Query: 125 SSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIISEHGE 184
               +   +  +KE   ++E  +++       E E+  +      +  +E+G    E GE
Sbjct: 796 GEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE 855

Query: 185 ---DEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDF 241
              +E   E E EEE  +  G              GE  +         + +   E G+ 
Sbjct: 856 GKGEEEGEEGEGEEEGEEGEG-------------EGEEEEGEGEGEEEGEGEGEEEEGEG 902

Query: 242 TPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALV 301
              +   G+G    E+E +   +E+ +E            + +   EE   EG D +   
Sbjct: 903 EGEEEGEGEG---EEEEGEGKGEEEGEE-----------GEGEGEEEEGEGEGEDGE--- 945

Query: 302 TGEQDEELSRWEQEQ 316
            GE +EE   WE E+
Sbjct: 946 -GEGEEEEGEWEGEE 959



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 41/249 (16%), Positives = 102/249 (40%), Gaps = 32/249 (12%)

Query: 89  LKPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKI 148
           ++ +K+ +   E+ + + L+  D+ +E EE+ ++K+        K  K+   + +  ++ 
Sbjct: 520 VQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEG-------KACKQHVSQGIFMTQP 572

Query: 149 KTELNSSAESEQPLDKTGHVKDTNQEDGVIISEHGEDEMDMESEKEEEKPKTGGAFSNAL 208
            T + + ++ E  + +     + ++ +G+       +E ++E+ +E  K   G      +
Sbjct: 573 ATTIEAFSDEEVEIPEEKEGAEDSKGNGI-------EEQEVEANEENVKVHGGRKEKTEI 625

Query: 209 SSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHDN-----------------EPGKG 251
            S ++    E+ +     +  +        GD T  +                  + G+G
Sbjct: 626 LSDDLTDKAEVSEGK-AKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRG 684

Query: 252 RLVREDENDASDDEDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEELSR 311
            + R  E +    E ++ K+R     ++K + Q   +E   E  +      GE +EE   
Sbjct: 685 EMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGD 744

Query: 312 WEQEQIRKG 320
            E+E+ ++G
Sbjct: 745 REEEEEKEG 753


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 12/177 (6%)

Query: 99  KEVPRASLLSFQDEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAES 158
           KEVP   L   +DEEEE+ +  KVK+ +     +K  K   K++  KS IK ++   AE+
Sbjct: 617 KEVPTQFL--DRDEEEEDADFLKVKRHNVFGLDLKDEKTLQKKEPSKSSIKKKMTKVAEA 674

Query: 159 EQPLDKTGHV--KDTNQEDGVIISEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRP 216
           ++ + +   V  K T  ++G ++ +  + +     + EE+   TGG   N   +   L+ 
Sbjct: 675 KKVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEED-DDTGGI--NLHKAKERLQE 731

Query: 217 GEIPDAAFIHAARKKRQMARELGDFTPHDNEPGKGRLVREDENDA----SDDEDDDE 269
            +  D        K +   + L +      E  K +   +DE +A    SDD+DDD+
Sbjct: 732 EDKFDKEEYRKKIKAKHREKRLKEREAR-REANKRQAKAKDEEEAFLDWSDDDDDDD 787



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 12/103 (11%)

Query: 469 ESAIHQLYKQRASRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSFGRD---RALYQEHA 525
           E  + Q + Q     ++  ++D  D++   + H  K  +    D F ++   + +  +H 
Sbjct: 693 EGELVQQWPQMQKSAIKDAEED--DDTGGINLHKAKERLQEE-DKFDKEEYRKKIKAKHR 749

Query: 526 KRRIAEREARRTRRRQAREQTGKMADHLEGLS--SDDEETSTD 566
           ++R+ EREA    RR+A ++  K  D  E     SDD++   D
Sbjct: 750 EKRLKEREA----RREANKRQAKAKDEEEAFLDWSDDDDDDDD 788


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 3/60 (5%)

Query: 29  PPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPGLGAEAGGGFPGGAEPGNG 88
           PPP +PPPG+     P  G   PG    + P P PP A   G       G PG   PG+G
Sbjct: 233 PPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHG---PPSAGTPGAGHPGHG 289



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 25/80 (31%), Positives = 30/80 (37%), Gaps = 13/80 (16%)

Query: 29  PPPLLP---PPGTGEEAGPGGGDRAPG--GESLLGPGPSPPSALT-PGLG-------AEA 75
           PP + P   PPG      P  G    G  G     P P PP  +  PG+           
Sbjct: 258 PPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPH 317

Query: 76  GGGFPGGAEPGNGLKPRKRP 95
           G G P    PG+G +P  RP
Sbjct: 318 GLGHPHAGPPGSGGQPPPRP 337


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 61/285 (21%), Positives = 105/285 (36%), Gaps = 20/285 (7%)

Query: 9    NVRKRNDSEEEE----RERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESL--LGPGPS 62
            N  K+ D +  E    + RDE+ E       P   +++  G  ++      L   G G S
Sbjct: 1436 NRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDS 1495

Query: 63   PPSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKV 122
              S  +P    +          P +        R N+E         +D E+   E    
Sbjct: 1496 KKSNSSPSRDRK----------PHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNN 1545

Query: 123  KKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQP-LDKTGHVK-DTNQEDGVIIS 180
            K+SS +K +  L   E +  +EK +I  +++ S    +P L  +  +  D  +E      
Sbjct: 1546 KESSGNKLLYILNPPETQ--VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAF 1603

Query: 181  EHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGD 240
            E   +E D ES    ++ ++ G  S  L    V +  E  D A +      R  +     
Sbjct: 1604 EPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPS 1663

Query: 241  FTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQK 285
             +P  +    G   R   + AS  E  D K++     K+K ++ K
Sbjct: 1664 VSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHK 1708


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 61/285 (21%), Positives = 105/285 (36%), Gaps = 20/285 (7%)

Query: 9    NVRKRNDSEEEE----RERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESL--LGPGPS 62
            N  K+ D +  E    + RDE+ E       P   +++  G  ++      L   G G S
Sbjct: 1470 NRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDS 1529

Query: 63   PPSALTPGLGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKV 122
              S  +P    +          P +        R N+E         +D E+   E    
Sbjct: 1530 KKSNSSPSRDRK----------PHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNN 1579

Query: 123  KKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQP-LDKTGHVK-DTNQEDGVIIS 180
            K+SS +K +  L   E +  +EK +I  +++ S    +P L  +  +  D  +E      
Sbjct: 1580 KESSGNKLLYILNPPETQ--VEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAF 1637

Query: 181  EHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGD 240
            E   +E D ES    ++ ++ G  S  L    V +  E  D A +      R  +     
Sbjct: 1638 EPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPS 1697

Query: 241  FTPHDNEPGKGRLVREDENDASDDEDDDEKRRIVFSVKEKSQRQK 285
             +P  +    G   R   + AS  E  D K++     K+K ++ K
Sbjct: 1698 VSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHK 1742



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 36/152 (23%), Positives = 57/152 (37%), Gaps = 22/152 (14%)

Query: 29  PPPLLPPPGTGEEAGPG-----------GGDRAPGGESLLGPG--PSPPSALTPGLGAEA 75
           PPPL PPP       PG            G   P G S+  PG  P+P +  TP + +  
Sbjct: 561 PPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGV 620

Query: 76  GGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYSKKIV--K 133
                    P     P  R    +E  R        EEE+ +       + ++K+++  K
Sbjct: 621 QTAH-SNTIPTTQAPPLSREEFYREQRRLK------EEEKKKSKLDEFTNDFAKELMEYK 673

Query: 134 LLKKEYKEDLEKSKIKTELNSSAESEQPLDKT 165
            ++KE +    +SK     +S + S     K+
Sbjct: 674 KIQKERRRSFSRSKSPYSGSSYSRSSYTYSKS 705


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 43/210 (20%), Positives = 90/210 (42%), Gaps = 22/210 (10%)

Query: 111 DEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKD 170
           +E  +N E    +  +  K+IV++ ++  ++  EK   K E  ++    +  D+    +D
Sbjct: 77  NENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEED 136

Query: 171 TNQEDGVIISEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEI-----PDAAFI 225
            N+E G    E G+++ D + E++ ++ K G             + GE       D    
Sbjct: 137 QNEEKG----EAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEK 192

Query: 226 HAARKKRQMARELGDFTPH-------DNEPGKGRLVREDENDASDDEDDDEKRRIVFSVK 278
               K+ +  +E GD   +       D + GK   V+EDE +  D ++D+         +
Sbjct: 193 GEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGN------E 246

Query: 279 EKSQRQKIAEEIGIEGSDDDALVTGEQDEE 308
           E++ ++K   +   EG ++D +   +  +E
Sbjct: 247 EEAGKEKEDLKEEEEGKEEDEIKEDDGKKE 276


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 53/251 (21%), Positives = 101/251 (40%), Gaps = 28/251 (11%)

Query: 74  EAGGGFPGGAEPGNGLK--PRKRP------RENKEVPRASLLSFQDEEEENEEVFKVKKS 125
           E GG F  GA   N  +  P K        +E++E            ++E+EE   V+ S
Sbjct: 435 EDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGS 494

Query: 126 SYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIISEHGED 185
                  +  KK  K D E++ +  E       E   ++ G  K++ ++D     E  ED
Sbjct: 495 EEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESE-EEVGPTKESEEDDSE--KESDED 551

Query: 186 EMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHD 245
             + +SE   E+          L         E      +H     +++     + +  +
Sbjct: 552 CSEKQSEDGSEREFEENGLEKDLD--------EEGSEKELHENVLDKELEENDSENSEFE 603

Query: 246 NEPGKGRLVREDENDASDDEDDDEKR-------RIVFSVKEKSQRQKIAEEIGIEGSDDD 298
           ++ G  +++ E+ ++   DED DEK        ++     ++ + ++ A+E G+E +D  
Sbjct: 604 DD-GSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKK 662

Query: 299 ALVTGEQDEEL 309
           A   G+ DE+L
Sbjct: 663 A-EEGDADEKL 672


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 53/251 (21%), Positives = 101/251 (40%), Gaps = 28/251 (11%)

Query: 74  EAGGGFPGGAEPGNGLK--PRKRP------RENKEVPRASLLSFQDEEEENEEVFKVKKS 125
           E GG F  GA   N  +  P K        +E++E            ++E+EE   V+ S
Sbjct: 435 EDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGS 494

Query: 126 SYSKKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIISEHGED 185
                  +  KK  K D E++ +  E       E   ++ G  K++ ++D     E  ED
Sbjct: 495 EEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESE-EEVGPTKESEEDDSE--KESDED 551

Query: 186 EMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHD 245
             + +SE   E+          L         E      +H     +++     + +  +
Sbjct: 552 CSEKQSEDGSEREFEENGLEKDLD--------EEGSEKELHENVLDKELEENDSENSEFE 603

Query: 246 NEPGKGRLVREDENDASDDEDDDEKR-------RIVFSVKEKSQRQKIAEEIGIEGSDDD 298
           ++ G  +++ E+ ++   DED DEK        ++     ++ + ++ A+E G+E +D  
Sbjct: 604 DD-GSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKK 662

Query: 299 ALVTGEQDEEL 309
           A   G+ DE+L
Sbjct: 663 A-EEGDADEKL 672


>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
          Length = 1441

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/215 (19%), Positives = 81/215 (37%), Gaps = 26/215 (12%)

Query: 129  KKIVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIISEHGEDEMD 188
            K I  +L +E KE+    +              LD   ++ +   ED   IS+  +DE  
Sbjct: 1061 KDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFV 1120

Query: 189  MESEKEEEKPKTGGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHDNEP 248
            +  E  +E  +   +  ++ +     R    P      + R +R+  ++   ++  D E 
Sbjct: 1121 VSDENPDESEEDPPSNDDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKK--KYSDDDEEE 1178

Query: 249  GKGRLVREDENDASDDEDDD------------EKRRIVFSVKEKSQ------------RQ 284
                  R+ E+D SDD  DD            +KR+I +    +S             R+
Sbjct: 1179 ESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRR 1238

Query: 285  KIAEEIGIEGSDDDALVTGEQDEELSRWEQEQIRK 319
                 +    S++  L    +D+EL++  +  +RK
Sbjct: 1239 VHKRRLSSSESEESYLSKNSEDDELAKESKRSVRK 1273



 Score = 30.8 bits (68), Expect = 5.3
 Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 33/142 (23%)

Query: 90   KPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYS------------KKIVKLLKK 137
            +P ++ R  +        S  DEEEE+EE  +  +S +S            ++  +  K+
Sbjct: 1154 RPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKR 1213

Query: 138  E--YKEDLE--------------KSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIISE 181
            +  YKED E              +   K  L+SS   E  L K     +  +E    + +
Sbjct: 1214 QINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKESKRSVRK 1273

Query: 182  HGE-----DEMDMESEKEEEKP 198
             G       E D E E+EE KP
Sbjct: 1274 RGRSTDEYSEADEEEEEEEGKP 1295


>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
           [Homo sapiens]
          Length = 845

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 49/261 (18%), Positives = 113/261 (43%), Gaps = 34/261 (13%)

Query: 93  KRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTEL 152
           K+ +++K++ +        E+++  E  KV K    ++  +  +++ K D  K + K ++
Sbjct: 29  KKGKKDKKIKKTFFEELAVEDKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDV 88

Query: 153 NSSAESEQPLDKTGHVKDTNQEDGVIISEHGEDEMDMESEKEEEKPKTGGAFSNALSSLN 212
           +   E ++ +++   +     ++        EDE+     +  +K K G  F+  +   +
Sbjct: 89  DDDGEEKELMERLKKLSVPTSDE--------EDEVPAPKPRGGKKTKGGNVFAALIQDQS 140

Query: 213 VLRPGEI--------PDAAFIHAARKKRQMARELGDFTPHDNEPGKGRLVREDENDASDD 264
                E         P+   I+ A  + Q     G       E  KG+   +++  A D+
Sbjct: 141 EEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGK--KGKEEKSKGKAKPQNKFAALDN 198

Query: 265 EDDDEKRRIVFSVKEKSQRQKIAEEIGIEGSDDDALVTGEQDEE-------------LSR 311
           E++D++  I+   KE  ++ K   +   +GS+++    GE++EE             LS+
Sbjct: 199 EEEDKEEEII-KEKEPPKQGKEKAKKAEQGSEEEG--EGEEEEEEGGESKADDPYAHLSK 255

Query: 312 WEQEQIRKGINIPQVQASQPA 332
            E+++++K +   +  AS  A
Sbjct: 256 KEKKKLKKQMEYERQVASLKA 276


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 75/324 (23%), Positives = 115/324 (35%), Gaps = 34/324 (10%)

Query: 11  RKRNDSEEEERERDEEQEPPPLLPPPGTGEEAGPGGGDRAPGGESLLGPGPSPPSALTPG 70
           RKR     E     E   P    PP   G  A            +      S        
Sbjct: 91  RKRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRD 150

Query: 71  LGAEAGGGFPGGAEPGNGLKPRKRPRENKEVPRASLLSFQDEEEENEEVFKVKKSSYSKK 130
           L A+ G       E G   K RK+P   K+ P  + +S +   EE+EE       S ++ 
Sbjct: 151 LPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEE-------SEAEP 203

Query: 131 IVKLLKKEYKEDLEKSKIKTELNSSAESEQPLDKTGHVKDTNQEDGVIISEHGEDEMDME 190
           + +  KK     +E +K    L  S E E   +     K+  +E      E  E+E + +
Sbjct: 204 VQRTAKK-----VEGNKGTKSLKES-EQESEEEILAQKKEQREE------EVEEEEKEED 251

Query: 191 SEKEEEKPKT--GGAFSNALSSLNVLRPGEIPDAAFIHAARKKRQMARELGDFTPHDNEP 248
            EK + KP+T   G   +A    +  +  +         + ++++ A   GD +  D EP
Sbjct: 252 EEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREP 311

Query: 249 GKGRLVREDE---------NDASDDEDDDEKRRIVFSVKEKSQR--QKIAEEIGIEGS-D 296
              R   ED          + +S+DE+D  K         K  R      EE  +E    
Sbjct: 312 PVQR-KSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEESDLEREVS 370

Query: 297 DDALVTGEQDEELSRWEQEQIRKG 320
           D     G Q E  +R  ++  RKG
Sbjct: 371 DSEAGGGPQGERKNRSSKKSSRKG 394


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/209 (20%), Positives = 95/209 (45%), Gaps = 25/209 (11%)

Query: 395  LKDRLDSMKELHKTNRQQHEKHLQSRVDSTRAIERLEGSSGGIGERYKFLQEMRGYVQDL 454
            +++++ ++ ++ K  R+   ++ + +    + +E    SSG   E++  +QEM    Q+L
Sbjct: 1424 IQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEM----QEL 1479

Query: 455  LECFSEKVPLINELESAIHQLYKQRASRLVQRRQDDIKDESSEFSSHSNKALMAPNLDSF 514
             E  ++       LES +  L K  + +  + R  ++++++ +  S  ++      L   
Sbjct: 1480 KETLNQAETKSKSLESQVENLQKTLSEKETEAR--NLQEQTVQLQSELSR------LRQD 1531

Query: 515  GRDRALYQEHAKRRIAEREARRTRRRQAREQTGKMADHLEGLSSDDEETSTDITNFNLEK 574
             +DR   +E  +++I E+E    + R+A         HL G+   D+ T         E 
Sbjct: 1532 LQDRTTQEEQLRQQITEKE---EKTRKAIVAAKSKIAHLAGVK--DQLTK--------EN 1578

Query: 575  DRISKESGKVFEDVLESFYSIDCIKSQFE 603
            + + + +G + +   E    I  +KSQ+E
Sbjct: 1579 EELKQRNGALDQQKDELDVRITALKSQYE 1607


>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
          Length = 1173

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 77/327 (23%), Positives = 117/327 (35%), Gaps = 43/327 (13%)

Query: 10   VRKRNDSEEEERERDEEQEPPPLLPPPG------------TGE-------EAGPGGGDRA 50
            +R++   E+EE+   E++E   LL                TGE       + G GGG R+
Sbjct: 852  LRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRS 911

Query: 51   PGG---ESLLGPGPSPPSALTPGLGAEAGGGFP--GGAEPGNGLKPRKRPRENKEVPRAS 105
              G   +  +         ++       G G    G  E G   K +KR R     P+  
Sbjct: 912  KKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRH----PKGE 967

Query: 106  LLSFQDEEEENEEVFKVKKSSYSKKIVKLLKKEYKEDLEKSKIKTEL------NSSAESE 159
              S  DE E   +  K +     KK  K  K E      K KIK++       +SS E +
Sbjct: 968  EGSDDDETENGPKPKKRRPPKAEKK--KAPKPERLPPSMKGKIKSKAIISSSDDSSDEDK 1025

Query: 160  QPLDKTGHVKDTNQEDGVIISEHGEDEMDMESEKEEEKPKTGGAFSNALSSLNVLRPGEI 219
              +   GH +++N        E  +     ES+ +E + K+G   S A S     R    
Sbjct: 1026 LKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSG---SEAGSPRRPRRQRSD 1082

Query: 220  PDAAFIHAARKKRQMARELGDFTPHDNEPGKGRLVREDENDASDD-EDDDEKRRIVFSVK 278
             D+     +RK+R    E  D     +      +   D   AS   E D E  R      
Sbjct: 1083 QDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESER---GSD 1139

Query: 279  EKSQRQKIAEEIGIEGSDDDALVTGEQ 305
             +   Q    E   EGS+++A   G +
Sbjct: 1140 NEGSGQGSGNESEPEGSNNEASDRGSE 1166


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,829,167
Number of Sequences: 37866
Number of extensions: 1985145
Number of successful extensions: 20984
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 1036
Number of HSP's that attempted gapping in prelim test: 14270
Number of HSP's gapped (non-prelim): 6693
length of query: 815
length of database: 18,247,518
effective HSP length: 111
effective length of query: 704
effective length of database: 14,044,392
effective search space: 9887251968
effective search space used: 9887251968
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.