Guide to the Human Genome
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Search of human proteins with 115298678

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115298678 complement component 3 precursor [Homo sapiens]
         (1663 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115298678 complement component 3 precursor [Homo sapiens]         3320   0.0  
gi|169218213 PREDICTED: similar to complement component C3, part...  2561   0.0  
gi|169214179 PREDICTED: similar to complement component 3 [Homo ...   803   0.0  
gi|38016947 complement component 5 preproprotein [Homo sapiens]       675   0.0  
gi|178557739 complement component 4B preproprotein [Homo sapiens]     642   0.0  
gi|67190748 complement component 4A preproprotein [Homo sapiens]      637   0.0  
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s...   636   0.0  
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s...   632   0.0  
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]         224   4e-58
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]         224   4e-58
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]               219   1e-56
gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]         216   2e-55
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]            214   7e-55
gi|162809334 pregnancy-zone protein [Homo sapiens]                    202   2e-51
gi|239758130 PREDICTED: similar to complement component 4B (Chil...   200   8e-51
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta...   183   1e-45
gi|169204289 PREDICTED: ovostatin [Homo sapiens]                      173   1e-42
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]                    171   5e-42
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg...   127   1e-28
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]          80   1e-14
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...    67   2e-10
gi|239755748 PREDICTED: ovostatin [Homo sapiens]                       52   6e-06
gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]             44   0.001
gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sap...    44   0.001
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]          36   0.36 
gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...    35   0.46 
gi|226246554 hypothetical protein LOC643677 [Homo sapiens]             34   1.0  
gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sap...    34   1.0  
gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sap...    34   1.0  
gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sap...    34   1.0  

>gi|115298678 complement component 3 precursor [Homo sapiens]
          Length = 1663

 Score = 3320 bits (8609), Expect = 0.0
 Identities = 1663/1663 (100%), Positives = 1663/1663 (100%)

Query: 1    MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH 60
            MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH
Sbjct: 1    MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH 60

Query: 61   DFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKV 120
            DFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKV
Sbjct: 61   DFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKV 120

Query: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180
            VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL
Sbjct: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180

Query: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
            SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE
Sbjct: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240

Query: 241  KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEV 300
            KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEV
Sbjct: 241  KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEV 300

Query: 301  VLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKT 360
            VLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKT
Sbjct: 301  VLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKT 360

Query: 361  PKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPL 420
            PKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPL
Sbjct: 361  PKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPL 420

Query: 421  SITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMD 480
            SITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMD
Sbjct: 421  SITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMD 480

Query: 481  RAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGA 540
            RAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGA
Sbjct: 481  RAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGA 540

Query: 541  SGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDK 600
            SGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDK
Sbjct: 541  SGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDK 600

Query: 601  GVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAEL 660
            GVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAEL
Sbjct: 601  GVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAEL 660

Query: 661  QCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEAC 720
            QCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEAC
Sbjct: 661  QCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEAC 720

Query: 721  KKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKE 780
            KKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKE
Sbjct: 721  KKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKE 780

Query: 781  PPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV 840
            PPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV
Sbjct: 781  PPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV 840

Query: 841  RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVI 900
            RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVI
Sbjct: 841  RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVI 900

Query: 901  VPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKE 960
            VPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKE
Sbjct: 901  VPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKE 960

Query: 961  DIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTP 1020
            DIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTP
Sbjct: 961  DIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTP 1020

Query: 1021 TVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTA 1080
            TVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTA
Sbjct: 1021 TVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTA 1080

Query: 1081 YVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKD 1140
            YVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKD
Sbjct: 1081 YVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKD 1140

Query: 1141 MALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG 1200
            MALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG
Sbjct: 1141 MALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG 1200

Query: 1201 RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR 1260
            RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR
Sbjct: 1201 RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR 1260

Query: 1261 YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLR 1320
            YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLR
Sbjct: 1261 YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLR 1320

Query: 1321 SEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDA 1380
            SEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDA
Sbjct: 1321 SEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDA 1380

Query: 1381 KNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSD 1440
            KNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSD
Sbjct: 1381 KNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSD 1440

Query: 1441 RNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDG 1500
            RNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDG
Sbjct: 1441 RNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDG 1500

Query: 1501 KLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDE 1560
            KLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDE
Sbjct: 1501 KLNKLCRDELCRCAEENCFIQKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDE 1560

Query: 1561 YIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSY 1620
            YIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSY
Sbjct: 1561 YIMAIEQTIKSGSDEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSY 1620

Query: 1621 IIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN 1663
            IIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN
Sbjct: 1621 IIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGCPN 1663


>gi|169218213 PREDICTED: similar to complement component C3, partial
            [Homo sapiens]
          Length = 1295

 Score = 2561 bits (6639), Expect = 0.0
 Identities = 1294/1295 (99%), Positives = 1294/1295 (99%)

Query: 1    MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH 60
            MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH
Sbjct: 1    MGPTSGPSLLLLLLTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH 60

Query: 61   DFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKV 120
            DFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKV
Sbjct: 61   DFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKV 120

Query: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180
            VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL
Sbjct: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180

Query: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
            SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE
Sbjct: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240

Query: 241  KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEV 300
            KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEV
Sbjct: 241  KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEV 300

Query: 301  VLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKT 360
            VLSRKVLLDGVQN RAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKT
Sbjct: 301  VLSRKVLLDGVQNLRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKT 360

Query: 361  PKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPL 420
            PKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPL
Sbjct: 361  PKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPL 420

Query: 421  SITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMD 480
            SITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMD
Sbjct: 421  SITVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMD 480

Query: 481  RAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGA 540
            RAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGA
Sbjct: 481  RAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGA 540

Query: 541  SGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDK 600
            SGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDK
Sbjct: 541  SGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDK 600

Query: 601  GVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAEL 660
            GVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAEL
Sbjct: 601  GVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAEL 660

Query: 661  QCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEAC 720
            QCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEAC
Sbjct: 661  QCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEAC 720

Query: 721  KKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKE 780
            KKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKE
Sbjct: 721  KKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVSRSEFPESWLWNVEDLKE 780

Query: 781  PPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV 840
            PPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV
Sbjct: 781  PPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVV 840

Query: 841  RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVI 900
            RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVI
Sbjct: 841  RNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVI 900

Query: 901  VPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKE 960
            VPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKE
Sbjct: 901  VPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKE 960

Query: 961  DIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTP 1020
            DIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTP
Sbjct: 961  DIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTP 1020

Query: 1021 TVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTA 1080
            TVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTA
Sbjct: 1021 TVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPSTWLTA 1080

Query: 1081 YVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKD 1140
            YVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKD
Sbjct: 1081 YVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKD 1140

Query: 1141 MALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG 1200
            MALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG
Sbjct: 1141 MALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMG 1200

Query: 1201 RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR 1260
            RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR
Sbjct: 1201 RLKGPLLNKFLTTAKDKNRWEDPGKQLYNVEATSYALLALLQLKDFDFVPPVVRWLNEQR 1260

Query: 1261 YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLD 1295
            YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLD
Sbjct: 1261 YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLD 1295


>gi|169214179 PREDICTED: similar to complement component 3 [Homo
            sapiens]
          Length = 390

 Score =  803 bits (2075), Expect = 0.0
 Identities = 390/390 (100%), Positives = 390/390 (100%)

Query: 1274 MVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVT 1333
            MVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVT
Sbjct: 1    MVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVT 60

Query: 1334 AEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYR 1393
            AEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYR
Sbjct: 61   AEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYR 120

Query: 1394 GDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSH 1453
            GDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSH
Sbjct: 121  GDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSH 180

Query: 1454 SEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRC 1513
            SEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRC
Sbjct: 181  SEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRC 240

Query: 1514 AEENCFIQKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGS 1573
            AEENCFIQKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGS
Sbjct: 241  AEENCFIQKSDDKVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGS 300

Query: 1574 DEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKDTWVEHWPE 1633
            DEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKDTWVEHWPE
Sbjct: 301  DEVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKDTWVEHWPE 360

Query: 1634 EDECQDEENQKQCQDLGAFTESMVVFGCPN 1663
            EDECQDEENQKQCQDLGAFTESMVVFGCPN
Sbjct: 361  EDECQDEENQKQCQDLGAFTESMVVFGCPN 390


>gi|38016947 complement component 5 preproprotein [Homo sapiens]
          Length = 1676

 Score =  675 bits (1741), Expect = 0.0
 Identities = 473/1698 (27%), Positives = 817/1698 (48%), Gaps = 106/1698 (6%)

Query: 26   YSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEKTVLTPATNHMGN 85
            Y I  P I R+ + E +V++ +        T+++  +P KK   SS    L+       +
Sbjct: 23   YVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKKFSYSSGHVHLSSENKFQNS 82

Query: 86   VTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTV 145
               TI   ++    +    +V ++         K + ++  +G+LFI TDK +YTP  +V
Sbjct: 83   AILTIQP-KQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQSV 141

Query: 146  LYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPL-SWDIPELVNMGQW 204
              R++++N  L P  R  ++   +PEG  V  D +   + +G++    + IP     G W
Sbjct: 142  KVRVYSLNDDLKPAKRETVLTFIDPEGSEV--DMVEEIDHIGIISFPDFKIPSNPRYGMW 199

Query: 205  KIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKK 264
             I+A Y+       +  FEVKEYVLP F V +EP   F    N K  E+TI AR+ Y K 
Sbjct: 200  TIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKV 259

Query: 265  V-EGTAFVIFGIQDG---EQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLV 320
            V E   ++ FGI++    +Q+  +  +++   + +G  +V    +  +  +     EDL 
Sbjct: 260  VTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSETAVKELSYYSLEDLN 319

Query: 321  GKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPD 380
             K LY++ TVI  +G    +AE  GI  V SPY+++   TP + KPG+P+ + V V +  
Sbjct: 320  NKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSL 379

Query: 381  GSPAYRVPVAVQGE-----------DTVQSLTQ-GDGVAKLSINTHPSQKPLSITVRTKK 428
                  VPV +  +           D  +S+T+  DGVA   +N       L   V+T  
Sbjct: 380  DQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASFVLNLPSGVTVLEFNVKTDA 439

Query: 429  QELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLRMDRAHEAKIR 488
             +L E  QA    +A+ YS++  S  Y+  +     L  GE LN+  ++     +  KI 
Sbjct: 440  PDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGEHLNI--IVTPKSPYIDKIT 497

Query: 489  YYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVA 548
            +Y YLI++KG+++  G + +        + + +T + +PS RL+ YY + G     E+V+
Sbjct: 498  HYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRLLVYYIVTGEQ-TAELVS 556

Query: 549  DSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKK 608
            DSVW+++++ C   L V      D    PGQ ++L +     + V L AVD  V+ + + 
Sbjct: 557  DSVWLNIEEKCGNQLQVHLSPDADAYS-PGQTVSLNMATGMDSWVALAAVDSAVYGVQRG 615

Query: 609  NKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAAR 668
             K    +++  +EK+D+GC  G G + A VF  AGLTF +++    +Q  +  C +   R
Sbjct: 616  AKKPLERVFQFLEKSDLGCGAGGGLNNANVFHLAGLTFLTNANADDSQENDEPCKE-ILR 674

Query: 669  RRRSVQLTEKRMDKVGKYPKE--LRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLD 726
             RR++Q   K+++++    K   ++KCC DG   N    +C++R   ISLG  C K F +
Sbjct: 675  PRRTLQ---KKIEEIAAKYKHSVVKKCCYDGACVNNDE-TCEQRAARISLGPRCIKAFTE 730

Query: 727  CCNYITELRRQHARASHLGLARSNLD-EDIIAEENIVSRSEFPESWLWNVEDLKEPPKNG 785
            CC   ++LR   A  SH  +    L  + ++       RS FPESWLW V  +       
Sbjct: 731  CCVVASQLR---ANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLVPR----- 782

Query: 786  ISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQV 845
               K +   L DS+TTWEI  V +S+  GICVAD  +  V +D F+++ +PYSVVR EQ+
Sbjct: 783  --RKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVFKDVFLEMNIPYSVVRGEQI 839

Query: 846  EIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVT-------IPPKSSLSVPY 898
            +++  +YNYR +  ++  V++      C+  +    HQ T +       +   SS  V +
Sbjct: 840  QLKGTVYNYRTSG-MQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTF 898

Query: 899  VIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQ 958
             ++PL+ GL  +      +  F  + + K+L+VVPEG++      V TLDP  +     +
Sbjct: 899  TVLPLEIGLHNINFSLETW--FGKEILVKTLRVVPEGVKRESYSGV-TLDPRGIYGTISR 955

Query: 959  KEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGM 1018
            +++ P     D VP TE +  + ++G  V ++    +  E +  L   P G  E  ++ +
Sbjct: 956  RKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSV 1015

Query: 1019 TPTVIAVHYLDETEQWEKFG---LEKRQGALELIKKGYTQQLAFRQPSSAFAAFVKRAPS 1075
             P     HYL+    W  F    L ++Q   + +K+G    +++R    +++ +   + S
Sbjct: 1016 VPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRNADYSYSVWKGGSAS 1075

Query: 1076 TWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLR- 1134
            TWLTA+ ++V       +  +   +C ++ WL+   Q  +G F+E++     ++ G L  
Sbjct: 1076 TWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPV 1135

Query: 1135 NNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGY 1194
               E  + LTAF +I +++A DIC   +  +  ++ KA +FL  N +  Q ++T+AI+ Y
Sbjct: 1136 EARENSLYLTAFTVIGIRKAFDICP--LVKIDTALIKADNFLLENTLPAQSTFTLAISAY 1193

Query: 1195 ALAQMGRLKGPLLNKFLTTAKDK----------NRWEDPGKQLYN----------VEATS 1234
            AL+ +G    P     ++  K +            W+D  +   +          VE T+
Sbjct: 1194 ALS-LGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTA 1252

Query: 1235 YALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNL 1294
            YALL  L LKD ++V PV++WL+E++ YGGG+ STQ T    + L +Y       ++L L
Sbjct: 1253 YALLTSLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLV---KQLRL 1309

Query: 1295 DVSLQLPSRSSKITHRIHWESASLL-RSEETKENEGFTV-TAEGKGQGTLSVVTMYHAKA 1352
             + + +  +     H       + L R  E   N+   V T  G G  T+ V T+ H  +
Sbjct: 1310 SMDIDVSYKHKGALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTS 1369

Query: 1353 KDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQDATMS-----ILDISM 1407
              +  C+ F LK+  +    +  R     +   +  C  Y+  ++ + S     ++DIS+
Sbjct: 1370 TSEEVCS-FYLKIDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISL 1428

Query: 1408 MTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYF 1467
             TG + + +DLK L  GVD+  + Y++         +I+ L+ +  S+  C+ F++ + F
Sbjct: 1429 PTGISANEEDLKALVEGVDQLFTDYQIKDGH-----VILQLNSIPSSDFLCVRFRIFELF 1483

Query: 1468 NVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENC--FIQKSDD 1525
             V  + P    VY Y+  ++ CT FY     + K+ K+C    C+C E +C    ++ D 
Sbjct: 1484 EVGFLSPATFTVYEYHRPDKQCTMFY--STSNIKIQKVCEGAACKCVEADCGQMQEELDL 1541

Query: 1526 KVTLEERLDKACEPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSDEVQVGQQRTFI 1585
             ++ E R   AC+P + Y YK  +  + + N F +Y   +    K+G    +   + TFI
Sbjct: 1542 TISAETRKQTACKPEIAYAYKVSITSITVENVFVKYKATLLDIYKTGEAVAEKDSEITFI 1601

Query: 1586 SPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKD--TWVEHWPEEDECQDEENQ 1643
              + C  A +L + + YL+ G  +       +  YI   D  TW+E+WP +  C     Q
Sbjct: 1602 KKVTCTNA-ELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTC--SSCQ 1658

Query: 1644 KQCQDLGAFTESMVVFGC 1661
                +L  F E + + GC
Sbjct: 1659 AFLANLDEFAEDIFLNGC 1676


>gi|178557739 complement component 4B preproprotein [Homo sapiens]
          Length = 1744

 Score =  642 bits (1657), Expect = 0.0
 Identities = 508/1657 (30%), Positives = 796/1657 (48%), Gaps = 162/1657 (9%)

Query: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180
            +L S + G+LF+QTD+ IY PG  V YR+F ++ K+ P   T+ V +EN  G+ V++  +
Sbjct: 132  LLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEV 191

Query: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
               +   +    + IP++   G WKI A + +  +   ST+FEVK+YVLP+FEV + P +
Sbjct: 192  YMPSS--IFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGK 249

Query: 241  KFYYIYNEKG----LEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLK-RIPIED 295
               YI    G    +++ I AR++YGK V+G A+V FG+ D + + +    L+ +  + +
Sbjct: 250  P--YILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVN 307

Query: 296  GSGEVVLSRKVLLDGVQ--NPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPY 353
            G   + LS+    D ++  N    DL G  LYV+A +I   G +M +AE +    V+SP+
Sbjct: 308  GQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPF 367

Query: 354  QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINT 413
             +  +KT ++  PG PF L   V    GSPA  +PV V    TV S      V  +  NT
Sbjct: 368  SLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSA--TVSSPGSVPEVQDIQQNT 425

Query: 414  HPS-QKPLSITVRTKKQELSEAEQATRTMQALPYSTVGN--SNNYLHLSVLRTELRP--- 467
              S Q  + I +     EL  +  A     A+   TV    S     LS+ R + RP   
Sbjct: 426  DGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRV 485

Query: 468  GETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIP 527
            G+TLN+N          A   +Y Y+I+++G+++   R   EP + L  + + +     P
Sbjct: 486  GDTLNLNLRAV---GSGATFSHYYYMILSRGQIVFMNR---EPKRTLTSVSVFVDHHLAP 539

Query: 528  SFRLVAYYTLIGASGQREVVADSVWVDVK-DSCVGSLVVK-SGQSEDRQPVPGQQMTLKI 585
            SF  VA+Y      G   V A+S+ VDV+  +C G L +   G  + R    G+ + L +
Sbjct: 540  SFYFVAFYY----HGDHPV-ANSLRVDVQAGACEGKLELSVDGAKQYRN---GESVKLHL 591

Query: 586  EGDHGARVVLVAVDKGVFVLNKKNK--LTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAG 643
            E D  A V L A+D  ++    K+   L   K+++ +   D+GC PG G     VF  AG
Sbjct: 592  ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651

Query: 644  LTFTSSSGQQTAQRAELQCP-QPAARRRRSVQLTEKRMDKVGKYPKELRK-CCEDGMREN 701
            L F S   Q T  R  L CP +   R++R+V   +   +K+G+Y     K CC+DG+   
Sbjct: 652  LAF-SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRL 710

Query: 702  PMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSN---LDEDIIAE 758
            PM  SC++R   +   + C++ FL CC +   LR++       GL R+     +ED+I E
Sbjct: 711  PMMRSCEQRAARVQQPD-CREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDE 769

Query: 759  ENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVA 818
            ++I  RS FPE+WLW VE +          +++ ++L DS+TTWEI  +S+S  KG+CVA
Sbjct: 770  DDIPVRSFFPENWLWRVETVDR-------FQILTLWLPDSLTTWEIHGLSLSKTKGLCVA 822

Query: 819  DPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATT 878
             P ++ V ++F + LRLP SV R EQ+E+R VLYNY  ++ L V V +      C LA  
Sbjct: 823  TPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYL-DKNLTVSVHVSPVEGLC-LAGG 880

Query: 879  KRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHF-ISDGVRKSLKVVPEGIR 937
                QQ V +P  S+  V + +VP       ++V A     F + D V K L++  EG  
Sbjct: 881  GGLAQQ-VLVPAGSARPVAFSVVPTAATAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA- 938

Query: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGT-PVAQM-TEDAV 995
            +++   V  L+P  L   G   E IP     + +PD +  + + +  + P+  + +E A+
Sbjct: 939  IHREELVYELNP--LDHRGRTLE-IPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGAL 995

Query: 996  DAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQ 1055
                +  L+  P GCGEQ MI + PT+ A  YLD+TEQW     E +  A++LI+KGY +
Sbjct: 996  SPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMR 1055

Query: 1056 QLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
               FR+   ++AA++ R  STWLTA+V+KV SLA   +    + L     WL L +Q+ D
Sbjct: 1056 IQQFRKADGSYAAWLSRGSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL-LSQQQAD 1114

Query: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQ-----VNSLPGSIT 1170
            G FQ+ +PVIH+ M GGL  N+E  +ALTAFV I+L     + +++        +  SI+
Sbjct: 1115 GSFQDLSPVIHRSMQGGLVGNDET-VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASIS 1173

Query: 1171 KAGDFL-EANYMNLQRSYTVAIAGYALAQM---GRLKGPLLNKFLTTAK---DKNRW--- 1220
            KA  FL E     L  ++  AI  YAL        L+G   N  +  A+   D   W   
Sbjct: 1174 KASSFLGEKASAGLLGAHAAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSV 1233

Query: 1221 -----------------EDPGKQLYN--VEATSYALLALLQLKD-FDFVPPVVRWLNEQR 1260
                              DP  Q     +E T+YALL LL  +   +       WL  Q 
Sbjct: 1234 TGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQG 1293

Query: 1261 YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLR 1320
             + GG+ STQ T +   AL+ Y   +   +E  L+V+L    R+   +H +   +  +  
Sbjct: 1294 SFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRG 1353

Query: 1321 SEETKE---NEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIK--------- 1368
             EE  +        V   G  +GTL V+  Y+       TC    ++VT+K         
Sbjct: 1354 LEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEA 1413

Query: 1369 ------------PAPETEKRPQDAKNTMILEICTRYRGDQDAT----------------- 1399
                        PA +    P      + L    R R  ++A                  
Sbjct: 1414 NEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIW 1473

Query: 1400 ---------MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDK 1450
                     M+I D+++++GF     DL++L +  DRY+S +E +        +++Y D 
Sbjct: 1474 RNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPH-----VLLYFDS 1528

Query: 1451 VSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDEL 1510
            V  S + C+ F+  Q   V L+QP +  +Y YYN E  C+ FY    +   L  LC  E+
Sbjct: 1529 VPTSRE-CVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEV 1587

Query: 1511 CRCAEENCFIQKSDDKVTLEE----RLDKAC-EPGVDYVYKTRLVKVQLSNDFDEYIMAI 1565
            C+CAE  C  Q+   +  L++    R+  AC  P V+Y ++ ++++      F  +   I
Sbjct: 1588 CQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKI 1647

Query: 1566 EQTIKSGSD-EVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGK 1624
             Q +    D +    Q R F+    CR  L+LE  K YL+ GL    +  + +  Y++  
Sbjct: 1648 TQVLHFTKDVKAAANQMRNFLVRASCR--LRLEPGKEYLIMGLDGATYDLEGHPQYLLDS 1705

Query: 1625 DTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGC 1661
            ++W+E  P E  C+    +  C  L  F +     GC
Sbjct: 1706 NSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1742


>gi|67190748 complement component 4A preproprotein [Homo sapiens]
          Length = 1744

 Score =  637 bits (1643), Expect = 0.0
 Identities = 503/1657 (30%), Positives = 791/1657 (47%), Gaps = 162/1657 (9%)

Query: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180
            +L S + G+LF+QTD+ IY PG  V YR+F ++ K+ P   T+ V +EN  G+ V++  +
Sbjct: 132  LLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEV 191

Query: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
               +   +    + IP++   G WKI A + +  +   ST+FEVK+YVLP+FEV + P +
Sbjct: 192  YMPSS--IFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGK 249

Query: 241  KFYYIYNEKG----LEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLK-RIPIED 295
               YI    G    +++ I AR++YGK V+G A+V FG+ D + + +    L+ +  + +
Sbjct: 250  P--YILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVN 307

Query: 296  GSGEVVLSRKVLLDGVQ--NPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPY 353
            G   + LS+    D ++  N    DL G  LYV+A +I   G +M +AE +    V+SP+
Sbjct: 308  GQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPF 367

Query: 354  QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINT 413
             +  +KT ++  PG PF L   V    GSPA  +PV V    TV S      V  +  NT
Sbjct: 368  SLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSA--TVSSPGSVPEVQDIQQNT 425

Query: 414  HPS-QKPLSITVRTKKQELSEAEQATRTMQALPYSTVGN--SNNYLHLSVLRTELRP--- 467
              S Q  + I +     EL  +  A     A+   TV    S     LS+ R + RP   
Sbjct: 426  DGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRV 485

Query: 468  GETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIP 527
            G+TLN+N          A   +Y Y+I+++G+++   R   EP + L  + + +     P
Sbjct: 486  GDTLNLNLRAV---GSGATFSHYYYMILSRGQIVFMNR---EPKRTLTSVSVFVDHHLAP 539

Query: 528  SFRLVAYYTLIGASGQREVVADSVWVDVK-DSCVGSLVVK-SGQSEDRQPVPGQQMTLKI 585
            SF  VA+Y      G   V A+S+ VDV+  +C G L +   G  + R    G+ + L +
Sbjct: 540  SFYFVAFYY----HGDHPV-ANSLRVDVQAGACEGKLELSVDGAKQYRN---GESVKLHL 591

Query: 586  EGDHGARVVLVAVDKGVFVLNKKNK--LTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAG 643
            E D  A V L A+D  ++    K+   L   K+++ +   D+GC PG G     VF  AG
Sbjct: 592  ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651

Query: 644  LTFTSSSGQQTAQRAELQCP-QPAARRRRSVQLTEKRMDKVGKYPKELRK-CCEDGMREN 701
            L F S   Q T  R  L CP +   R++R+V   +   +K+G+Y     K CC+DG+   
Sbjct: 652  LAF-SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRL 710

Query: 702  PMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSN---LDEDIIAE 758
            PM  SC++R   +   + C++ FL CC +   LR++       GL R+     +ED+I E
Sbjct: 711  PMMRSCEQRAARVQQPD-CREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDE 769

Query: 759  ENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVA 818
            ++I  RS FPE+WLW VE +          +++ ++L DS+TTWEI  +S+S  KG+CVA
Sbjct: 770  DDIPVRSFFPENWLWRVETVDR-------FQILTLWLPDSLTTWEIHGLSLSKTKGLCVA 822

Query: 819  DPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATT 878
             P ++ V ++F + LRLP SV R EQ+E+R VLYNY  ++ L V V +      C LA  
Sbjct: 823  TPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYL-DKNLTVSVHVSPVEGLC-LAGG 880

Query: 879  KRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHF-ISDGVRKSLKVVPEGIR 937
                QQ V +P  S+  V + +VP       ++V A     F + D V K L++  EG  
Sbjct: 881  GGLAQQ-VLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA- 938

Query: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGT-PVAQM-TEDAV 995
            +++   V  L+P  L   G   E IP     + +PD +  + + +  + P+  + +E A+
Sbjct: 939  IHREELVYELNP--LDHRGRTLE-IPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGAL 995

Query: 996  DAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQ 1055
                +  L+  P GCGEQ MI + PT+ A  YLD+TEQW     E +  A++LI+KGY +
Sbjct: 996  SPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMR 1055

Query: 1056 QLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
               FR+   ++AA++ R  STWLTA+V+KV SLA   +    + L     WL L +Q+ D
Sbjct: 1056 IQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL-LSQQQAD 1114

Query: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQ-----VNSLPGSIT 1170
            G FQ+  PV+ + M GGL  N+E  +ALTAFV I+L     + +++        +  SI+
Sbjct: 1115 GSFQDPCPVLDRSMQGGLVGNDET-VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASIS 1173

Query: 1171 KAGDFL-EANYMNLQRSYTVAIAGYALA---------------------------QMGRL 1202
            KA  FL E     L  ++  AI  YAL                              G +
Sbjct: 1174 KANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSV 1233

Query: 1203 KGPLLNKFLTTAKDKNRWED-PGKQLYNVEATSYALLALLQLKD-FDFVPPVVRWLNEQR 1260
             G   N    T   +N  +  P      +E T+YALL LL  +   +       WL  Q 
Sbjct: 1234 TGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQASAWLTRQG 1293

Query: 1261 YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLR 1320
             + GG+ STQ T +   AL+ Y   +   +E  L+V+L    R+   +H +   +  +  
Sbjct: 1294 SFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRG 1353

Query: 1321 SEETKE---NEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIK--------- 1368
             EE  +        V   G  +GTL V+  Y+       TC    ++VT+K         
Sbjct: 1354 LEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEA 1413

Query: 1369 ------------PAPETEKRPQDAKNTMILEICTRYRGDQDAT----------------- 1399
                        PA +    P      + L    R R  ++A                  
Sbjct: 1414 NEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIW 1473

Query: 1400 ---------MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDK 1450
                     M+I D+++++GF     DL++L +  DRY+S +E +        +++Y D 
Sbjct: 1474 RNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPH-----VLLYFDS 1528

Query: 1451 VSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDEL 1510
            V  S + C+ F+  Q   V L+QP +  +Y YYN E  C+ FY    +   L  LC  E+
Sbjct: 1529 VPTSRE-CVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEV 1587

Query: 1511 CRCAEENCFIQKSDDKVTLEE----RLDKAC-EPGVDYVYKTRLVKVQLSNDFDEYIMAI 1565
            C+CAE  C  Q+   +  L++    R+  AC  P V+Y ++ ++++      F  +   I
Sbjct: 1588 CQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKI 1647

Query: 1566 EQTIKSGSD-EVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGK 1624
             Q +    D +    Q R F+    CR  L+LE  K YL+ GL    +  + +  Y++  
Sbjct: 1648 TQVLHFTKDVKAAANQMRNFLVRASCR--LRLEPGKEYLIMGLDGATYDLEGHPQYLLDS 1705

Query: 1625 DTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGC 1661
            ++W+E  P E  C+    +  C  L  F +     GC
Sbjct: 1706 NSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1742


>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
            sapiens]
          Length = 1744

 Score =  636 bits (1640), Expect = 0.0
 Identities = 502/1657 (30%), Positives = 791/1657 (47%), Gaps = 162/1657 (9%)

Query: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180
            +L S + G+LF+QTD+ IY PG  V YR+F ++ K+ P   T+ V +EN  G+ V++  +
Sbjct: 132  LLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEV 191

Query: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
               +   +    + IP++   G WKI A + +  +   ST+FEVK+YVLP+FEV + P +
Sbjct: 192  YMPSS--IFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGK 249

Query: 241  KFYYIYNEKG----LEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLK-RIPIED 295
               YI    G    +++ I AR++YGK V+G A+V FG+ D + + +    L+ +  + +
Sbjct: 250  P--YILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVN 307

Query: 296  GSGEVVLSRKVLLDGVQ--NPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPY 353
            G   + LS+    D ++  N    DL G  LYV+A +I + G +M +AE +    V+SP+
Sbjct: 308  GQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPF 367

Query: 354  QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINT 413
             +  +KT ++  PG PF L   V    GSPA  +PV V    TV S      V  +  NT
Sbjct: 368  SLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSA--TVSSPGSVPEVQDIQQNT 425

Query: 414  HPS-QKPLSITVRTKKQELSEAEQATRTMQALPYSTVGN--SNNYLHLSVLRTELRP--- 467
              S Q  + I +     EL  +  A     A+   TV    S     LS+   + RP   
Sbjct: 426  DGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDSRPPRV 485

Query: 468  GETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIP 527
            G+TLN+N          A   +Y Y+I+++G+++   R   EP + L  + + +     P
Sbjct: 486  GDTLNLNLRAV---GSGATFSHYYYMILSRGQIVFMNR---EPKRTLTSVSVFVDHHLAP 539

Query: 528  SFRLVAYYTLIGASGQREVVADSVWVDVK-DSCVGSLVVK-SGQSEDRQPVPGQQMTLKI 585
            SF  VA+Y      G   V A+S+ VDV+  +C G L +   G  + R    G+ + L +
Sbjct: 540  SFYFVAFYY----HGDHPV-ANSLRVDVQAGACEGKLELSVDGAKQYRN---GESVKLHL 591

Query: 586  EGDHGARVVLVAVDKGVFVLNKKNK--LTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAG 643
            E D  A V L A+D  ++    K+   L   K+++ +   D+GC PG G     VF  AG
Sbjct: 592  ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651

Query: 644  LTFTSSSGQQTAQRAELQCP-QPAARRRRSVQLTEKRMDKVGKYPKELRK-CCEDGMREN 701
            L F S   Q T  R  L CP +   R++R+V   +   +K+G+Y     K CC+DG+   
Sbjct: 652  LAF-SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRL 710

Query: 702  PMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSN---LDEDIIAE 758
            PM  SC++R   +   + C++ FL CC +   LR++       GL R+     +ED+I E
Sbjct: 711  PMMRSCEQRAARVQQPD-CREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDE 769

Query: 759  ENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVA 818
            ++I  RS FPE+WLW VE +          +++ ++L DS+TTWEI  +S+S  KG+CVA
Sbjct: 770  DDIPVRSFFPENWLWRVETVDR-------FQILTLWLPDSLTTWEIHGLSLSKTKGLCVA 822

Query: 819  DPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATT 878
             P ++ V ++F + LRLP SV R EQ+E+R VLYNY  ++ L V V +      C LA  
Sbjct: 823  TPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYL-DKNLTVSVHVSPVEGLC-LAGG 880

Query: 879  KRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHF-ISDGVRKSLKVVPEGIR 937
                QQ V +P  S+  V + +VP       ++V A     F + D V K L++  EG  
Sbjct: 881  GGLAQQ-VLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA- 938

Query: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGT-PVAQM-TEDAV 995
            +++   V  L+P  L   G   E IP     + +PD +  + + +  + P+  + +E A+
Sbjct: 939  IHREELVYELNP--LDHRGRTLE-IPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGAL 995

Query: 996  DAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQ 1055
                +  L+  P GCGEQ MI + PT+ A  YLD+TEQW     E +  A++LI+KGY +
Sbjct: 996  SPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMR 1055

Query: 1056 QLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
               FR+   ++AA++ R  STWLTA+V+KV SLA   +    + L     WL L +Q+ D
Sbjct: 1056 IQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL-LSQQQAD 1114

Query: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQ-----VNSLPGSIT 1170
            G FQ+  PV+ + M GGL  N+E  +ALTAFV I+L     + +++        +  SI+
Sbjct: 1115 GSFQDPCPVLDRSMQGGLVGNDET-VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASIS 1173

Query: 1171 KAGDFL-EANYMNLQRSYTVAIAGYALA---------------------------QMGRL 1202
            KA  FL E     L  ++  AI  YAL                              G +
Sbjct: 1174 KANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSV 1233

Query: 1203 KGPLLNKFLTTAKDKNRWED-PGKQLYNVEATSYALLALLQLKD-FDFVPPVVRWLNEQR 1260
             G   N    T   +N  +  P      +E T+YALL LL  +   +       WL  Q 
Sbjct: 1234 TGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQG 1293

Query: 1261 YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLR 1320
             + GG+ STQ T +   AL+ Y   +   +E  L+V+L    R+   +H +   +  +  
Sbjct: 1294 SFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRG 1353

Query: 1321 SEETKE---NEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIK--------- 1368
             EE  +        V   G  +GTL V+  Y+       TC    ++VT+K         
Sbjct: 1354 LEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEA 1413

Query: 1369 ------------PAPETEKRPQDAKNTMILEICTRYRGDQDAT----------------- 1399
                        PA +    P      + L    R R  ++A                  
Sbjct: 1414 NEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIW 1473

Query: 1400 ---------MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDK 1450
                     M+I D+++++GF     DL++L +  DRY+S +E +        +++Y D 
Sbjct: 1474 RNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPH-----VLLYFDS 1528

Query: 1451 VSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDEL 1510
            V  S + C+ F+  Q   V L+QP +  +Y YYN E  C+ FY    +   L  LC  E+
Sbjct: 1529 VPTSRE-CVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEV 1587

Query: 1511 CRCAEENCFIQKSDDKVTLEE----RLDKAC-EPGVDYVYKTRLVKVQLSNDFDEYIMAI 1565
            C+CAE  C  Q+   +  L++    R+  AC  P V+Y ++ ++++      F  +   I
Sbjct: 1588 CQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKI 1647

Query: 1566 EQTIKSGSD-EVQVGQQRTFISPIKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGK 1624
             Q +    D +    Q R F+    CR  L+LE  K YL+ GL    +  + +  Y++  
Sbjct: 1648 TQVLHFTKDVKAAANQMRNFLVRASCR--LRLEPGKEYLIMGLDGATYDLEGHPQYLLDS 1705

Query: 1625 DTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGC 1661
            ++W+E  P E  C+    +  C  L  F +     GC
Sbjct: 1706 NSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1742


>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
            sapiens]
          Length = 1698

 Score =  632 bits (1630), Expect = 0.0
 Identities = 496/1613 (30%), Positives = 785/1613 (48%), Gaps = 120/1613 (7%)

Query: 121  VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180
            +L S + G+LF+QTD+ IY PG  V YR+F ++ K+ P   T+ V +EN  G+ V++  +
Sbjct: 132  LLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEV 191

Query: 181  SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
               +   +    + IP++   G WKI A + +  +   ST+FEVK+YVLP+FEV + P +
Sbjct: 192  YMPSS--IFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGK 249

Query: 241  KFYYIYNEKG----LEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLK-RIPIED 295
               YI    G    +++ I AR++YGK V+G A+V FG+ D + + +    L+ +  + +
Sbjct: 250  P--YILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVN 307

Query: 296  GSGEVVLSRKVLLDGVQ--NPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPY 353
            G   + LS+    D ++  N    DL G  LYV+A +I + G +M +AE +    V+SP+
Sbjct: 308  GQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPF 367

Query: 354  QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINT 413
             +  +KT ++  PG PF L   V    GSPA  +PV V    TV S      V  +  NT
Sbjct: 368  SLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSA--TVSSPGSVPEVQDIQQNT 425

Query: 414  HPS-QKPLSITVRTKKQELSEAEQATRTMQALPYSTVGN--SNNYLHLSVLRTELRP--- 467
              S Q  + I +     EL  +  A     A+   TV    S     LS+   + RP   
Sbjct: 426  DGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIEWPDSRPPRV 485

Query: 468  GETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIP 527
            G+TLN+N          A   +Y Y+I+++G+++   R   EP + L  + + +     P
Sbjct: 486  GDTLNLNLRAV---GSGATFSHYYYMILSRGQIVFMNR---EPKRTLTSVSVFVDHHLAP 539

Query: 528  SFRLVAYYTLIGASGQREVVADSVWVDVK-DSCVGSLVVK-SGQSEDRQPVPGQQMTLKI 585
            SF  VA+Y      G   V A+S+ VDV+  +C G L +   G  + R    G+ + L +
Sbjct: 540  SFYFVAFYY----HGDHPV-ANSLRVDVQAGACEGKLELSVDGAKQYRN---GESVKLHL 591

Query: 586  EGDHGARVVLVAVDKGVFVLNKKNK--LTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAG 643
            E D  A V L A+D  ++    K+   L   K+++ +   D+GC PG G     VF  AG
Sbjct: 592  ETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAG 651

Query: 644  LTFTSSSGQQTAQRAELQCP-QPAARRRRSVQLTEKRMDKVGKYPKELRK-CCEDGMREN 701
            L F S   Q T  R  L CP +   R++R+V   +   +K+G+Y     K CC+DG+   
Sbjct: 652  LAF-SDGDQWTLSRKRLSCPKEKTTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRL 710

Query: 702  PMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLARSN---LDEDIIAE 758
            PM  SC++R   +   + C++ FL CC +   LR++       GL R+     +ED+I E
Sbjct: 711  PMMRSCEQRAARVQQPD-CREPFLSCCQFAESLRKKSRDKGQAGLQRALEILQEEDLIDE 769

Query: 759  ENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVA 818
            ++I  RS FPE+WLW VE +          +++ ++L DS+TTWEI  +S+S  KG+CVA
Sbjct: 770  DDIPVRSFFPENWLWRVETVDR-------FQILTLWLPDSLTTWEIHGLSLSKTKGLCVA 822

Query: 819  DPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATT 878
             P ++ V ++F + LRLP SV R EQ+E+R VLYNY  ++ L V V +      C LA  
Sbjct: 823  TPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYL-DKNLTVSVHVSPVEGLC-LAGG 880

Query: 879  KRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHF-ISDGVRKSLKVVPEGIR 937
                QQ V +P  S+  V + +VP       ++V A     F + D V K L++  EG  
Sbjct: 881  GGLAQQ-VLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGA- 938

Query: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGT-PVAQM-TEDAV 995
            +++   V  L+P  L   G   E IP     + +PD +  + + +  + P+  + +E A+
Sbjct: 939  IHREELVYELNP--LDHRGRTLE-IPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGAL 995

Query: 996  DAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQ 1055
                +  L+  P GCGEQ MI + PT+ A  YLD+TEQW     E +  A++LI+KGY +
Sbjct: 996  SPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMR 1055

Query: 1056 QLAFRQPSSAFAAFVKRAPSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
               FR+   ++AA++ R  STWLTA+V+KV SLA   +    + L     WL L +Q+ D
Sbjct: 1056 IQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWL-LSQQQAD 1114

Query: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQ-----VNSLPGSIT 1170
            G FQ+  PV+ + M GGL  N+E  +ALTAFV I+L     + +++        +  SI+
Sbjct: 1115 GSFQDPCPVLDRSMQGGLVGNDET-VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASIS 1173

Query: 1171 KAGDFL-EANYMNLQRSYTVAIAGYALA---------------------------QMGRL 1202
            KA  FL E     L  ++  AI  YAL                              G +
Sbjct: 1174 KANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSV 1233

Query: 1203 KGPLLNKFLTTAKDKNRWED-PGKQLYNVEATSYALLALLQLKD-FDFVPPVVRWLNEQR 1260
             G   N    T   +N  +  P      +E T+YALL LL  +   +       WL  Q 
Sbjct: 1234 TGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQG 1293

Query: 1261 YYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLR 1320
             + GG+ STQ T +   AL+ Y   +   +E  L+V+L    R+   +H +   +  +  
Sbjct: 1294 SFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRG 1353

Query: 1321 SEETKE---NEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPE-TEKR 1376
             EE  +        V   G  +GTL V+  Y+       TC    ++VT+K   E T + 
Sbjct: 1354 LEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEA 1413

Query: 1377 PQDAKNTMILEICTRYRGDQDATMS-ILDISMMTGFAPDTD-DLKQLANGVDRYISKYEL 1434
             +D ++    E+  +   D DA +  +  + +  G       +  +L +  DRY+S +E 
Sbjct: 1414 NEDYEDYEYDELPAK--DDPDAPLQPVTPLQLFEGRRNRRRREAPKLTSLSDRYVSHFET 1471

Query: 1435 DKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYH 1494
            +        +++Y D V  S + C+ F+  Q   V L+QP +  +Y YYN E  C+ FY 
Sbjct: 1472 EGPH-----VLLYFDSVPTSRE-CVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYG 1525

Query: 1495 PEKEDGKLNKLCRDELCRCAEENCFIQKSDDKVTLEE----RLDKAC-EPGVDYVYKTRL 1549
               +   L  LC  E+C+CAE  C  Q+   +  L++    R+  AC  P V+Y ++ ++
Sbjct: 1526 APSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKV 1585

Query: 1550 VKVQLSNDFDEYIMAIEQTIKSGSD-EVQVGQQRTFISPIKCREALKLEEKKHYLMWGLS 1608
            ++      F  +   I Q +    D +    Q R F+    CR  L+LE  K YL+ GL 
Sbjct: 1586 LREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCR--LRLEPGKEYLIMGLD 1643

Query: 1609 SDFWGEKPNLSYIIGKDTWVEHWPEEDECQDEENQKQCQDLGAFTESMVVFGC 1661
               +  + +  Y++  ++W+E  P E  C+    +  C  L  F +     GC
Sbjct: 1644 GATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGC 1696


>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
          Length = 1368

 Score =  224 bits (572), Expect = 4e-58
 Identities = 212/785 (27%), Positives = 360/785 (45%), Gaps = 85/785 (10%)

Query: 764  RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGI-CVADPFE 822
            R  FPE+W+W   ++          +   + + DSIT+W      +S+  G+     P E
Sbjct: 610  RKHFPETWIWLDTNMGYR-----IYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 664

Query: 823  VTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNY-RQNQELKVRVELLHNPAFCSLATTKR- 880
            +   Q FFI L LPYSV+R E+  +   ++NY +   E+KV +E   +  F  L T+   
Sbjct: 665  LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIE--KSDKFDILMTSNEI 722

Query: 881  ---RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIR 937
                HQQT+ +P +   +V + I P  T L E+ +         SD V + + V  EGI 
Sbjct: 723  NATGHQQTLLVPSEDGATVLFPIRP--THLGEIPITVTALSPTASDAVTQMILVKAEGIE 780

Query: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
             + + ++  LD      +   K       LS   P         +Q T +  +   +++ 
Sbjct: 781  KSYSQSI-LLDLTDNRLQSTLK------TLSFSFPPNTVTGSERVQITAIGDVLGPSING 833

Query: 998  ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
              L  LI  P GCGEQNMI   P +  + YL + +Q      EK   AL  +++GY ++L
Sbjct: 834  --LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEK---ALSFMRQGYQREL 888

Query: 1058 AFRQPSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
             +++   +F+AF    P  STWL+A+V++ F  A   I ID  VL     WL    QK +
Sbjct: 889  LYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWL-KGHQKSN 947

Query: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF 1175
            G F +   VIH E+ GG    N+  + LTA+++ SL   +   + Q N     + ++  F
Sbjct: 948  GEFWDPGRVIHSELQGG----NKSPVTLTAYIVTSLLGYR---KYQPNI---DVQESIHF 997

Query: 1176 LEANY-MNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR----WEDPGKQL--- 1227
            LE+ +   +  +YT+A+  YAL+ +G  K       LT   ++      W     +L   
Sbjct: 998  LESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDS 1057

Query: 1228 -----YNVEATSYALLA-LLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQ 1281
                  ++E  +YALL+  LQ +  + + P++RWL+ QR   GG+ STQ T +  +AL++
Sbjct: 1058 WQPRSLDIEVAAYALLSHFLQFQTSEGI-PIMRWLSRQRNSLGGFASTQDTTVALKALSE 1116

Query: 1282 YQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEE--TKENEGFTVTAEGKGQ 1339
            +     + +  N+ V++  PS  S +   I   +  LL++ E    +     ++A G G 
Sbjct: 1117 FAA-LMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGF 1175

Query: 1340 GTLSVVTMYHAKAKDQLTCNK-------FDLKVTIKPAPETEKRPQDAKNTMILEICTRY 1392
                +  +Y+ KA       +       FDL V +       K  +D  N + L +CT +
Sbjct: 1176 AICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV-------KENKDDLNHVDLNVCTSF 1228

Query: 1393 RGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVS 1452
             G   + M+++++++++GF   ++     A  +   + K E      D   L +YLD V+
Sbjct: 1229 SGPGRSGMALMEVNLLSGFMVPSE-----AISLSETVKKVEY-----DHGKLNLYLDSVN 1278

Query: 1453 HSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRD-ELC 1511
             ++  C+     + F V   Q  +V +  YY       R Y+ E +    + LC D + C
Sbjct: 1279 ETQ-FCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCD-LCSDVQGC 1336

Query: 1512 RCAEE 1516
            R  E+
Sbjct: 1337 RPCED 1341



 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 127/569 (22%), Positives = 238/569 (41%), Gaps = 74/569 (13%)

Query: 123 VSLQSGYLFIQTDKTIYTPGSTVLYRI---------FTVNHKLLPVGRTVMVNIENPEGI 173
           +++  G  F+ T   I  PG  V   +          TV  +LL     + V++   EG+
Sbjct: 20  LAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGV 79

Query: 174 PVK-----------------QDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQ 216
             K                 Q  LS Q+ LGV+  ++ +     +G W I+    +   Q
Sbjct: 80  FEKGSFKTLTLPSDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVND---Q 136

Query: 217 VFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIF-GI 275
            +   F+V EYVLP FEV ++     Y   N K L  TITA++ YGK V+G   + F  +
Sbjct: 137 TYYQSFQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPL 194

Query: 276 QDGEQRISLPESLKRIPIEDGSGEVVLS---RKVLLDGVQNPRAE--DLVGKSLYVSATV 330
               ++ ++ ++ K     +GS     +    K ++D   N  +E  DL         T 
Sbjct: 195 SFWGKKKNITKTFK----INGSANFSFNDEEMKNVMDS-SNGLSEYLDLSSPGPVEILTT 249

Query: 331 ILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVA 390
           +  S + + +   + +      Y I F       KP + F   V VT  DG+   ++ + 
Sbjct: 250 VTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGN---QLTLE 306

Query: 391 VQGEDTVQSLTQGDGVAKLSINTHPSQK-----PLSITV---RTKKQELSEAEQATRTMQ 442
            +  + V ++TQ +     S +   +QK      ++ TV    T K E    E ++  +Q
Sbjct: 307 ERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSE-LQ 365

Query: 443 ALPYSTVGNSNNYLH---LSVLRTELR---PGETLNVNFLLRMDRAHEAKIRYYTYLIMN 496
              Y     S+  +H    S  +T ++     E + V     +  +   +++  +Y++++
Sbjct: 366 LKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVS 425

Query: 497 KGRLLKAGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVK 556
           +G+L+  G+      Q+  +  L+    + P   ++ YY         E+++D + + V+
Sbjct: 426 RGQLVAVGK------QNSTMFSLTPENSWTPKACVIVYY----IEDDGEIISDVLKIPVQ 475

Query: 557 DSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVV-LVAVDKGVFVLNKKNKLTQSK 615
              V    +K   S+ +   P ++++L+I       +V +VAVDK V ++N  N +T   
Sbjct: 476 --LVFKNKIKLYWSKVKAE-PSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMEN 532

Query: 616 IWDVVEKADIGCTPGSGKDYAGVFSDAGL 644
           +   +E  + G   G   +   VF + GL
Sbjct: 533 VVHELELYNTGYYLGMFMNSFAVFQECGL 561


>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
          Length = 1445

 Score =  224 bits (572), Expect = 4e-58
 Identities = 212/785 (27%), Positives = 360/785 (45%), Gaps = 85/785 (10%)

Query: 764  RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGI-CVADPFE 822
            R  FPE+W+W   ++          +   + + DSIT+W      +S+  G+     P E
Sbjct: 687  RKHFPETWIWLDTNMGYR-----IYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741

Query: 823  VTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNY-RQNQELKVRVELLHNPAFCSLATTKR- 880
            +   Q FFI L LPYSV+R E+  +   ++NY +   E+KV +E   +  F  L T+   
Sbjct: 742  LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIE--KSDKFDILMTSNEI 799

Query: 881  ---RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIR 937
                HQQT+ +P +   +V + I P  T L E+ +         SD V + + V  EGI 
Sbjct: 800  NATGHQQTLLVPSEDGATVLFPIRP--THLGEIPITVTALSPTASDAVTQMILVKAEGIE 857

Query: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
             + + ++  LD      +   K       LS   P         +Q T +  +   +++ 
Sbjct: 858  KSYSQSI-LLDLTDNRLQSTLK------TLSFSFPPNTVTGSERVQITAIGDVLGPSING 910

Query: 998  ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
              L  LI  P GCGEQNMI   P +  + YL + +Q      EK   AL  +++GY ++L
Sbjct: 911  --LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEK---ALSFMRQGYQREL 965

Query: 1058 AFRQPSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
             +++   +F+AF    P  STWL+A+V++ F  A   I ID  VL     WL    QK +
Sbjct: 966  LYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWL-KGHQKSN 1024

Query: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF 1175
            G F +   VIH E+ GG    N+  + LTA+++ SL   +   + Q N     + ++  F
Sbjct: 1025 GEFWDPGRVIHSELQGG----NKSPVTLTAYIVTSLLGYR---KYQPNI---DVQESIHF 1074

Query: 1176 LEANY-MNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR----WEDPGKQL--- 1227
            LE+ +   +  +YT+A+  YAL+ +G  K       LT   ++      W     +L   
Sbjct: 1075 LESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDS 1134

Query: 1228 -----YNVEATSYALLA-LLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQ 1281
                  ++E  +YALL+  LQ +  + + P++RWL+ QR   GG+ STQ T +  +AL++
Sbjct: 1135 WQPRSLDIEVAAYALLSHFLQFQTSEGI-PIMRWLSRQRNSLGGFASTQDTTVALKALSE 1193

Query: 1282 YQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEE--TKENEGFTVTAEGKGQ 1339
            +     + +  N+ V++  PS  S +   I   +  LL++ E    +     ++A G G 
Sbjct: 1194 FAA-LMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGF 1252

Query: 1340 GTLSVVTMYHAKAKDQLTCNK-------FDLKVTIKPAPETEKRPQDAKNTMILEICTRY 1392
                +  +Y+ KA       +       FDL V +       K  +D  N + L +CT +
Sbjct: 1253 AICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV-------KENKDDLNHVDLNVCTSF 1305

Query: 1393 RGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVS 1452
             G   + M+++++++++GF   ++     A  +   + K E      D   L +YLD V+
Sbjct: 1306 SGPGRSGMALMEVNLLSGFMVPSE-----AISLSETVKKVEY-----DHGKLNLYLDSVN 1355

Query: 1453 HSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRD-ELC 1511
             ++  C+     + F V   Q  +V +  YY       R Y+ E +    + LC D + C
Sbjct: 1356 ETQ-FCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCD-LCSDVQGC 1413

Query: 1512 RCAEE 1516
            R  E+
Sbjct: 1414 RPCED 1418



 Score =  104 bits (260), Expect = 6e-22
 Identities = 127/536 (23%), Positives = 240/536 (44%), Gaps = 49/536 (9%)

Query: 130 LFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVL 189
           +FIQTDK +Y P   V +RI T+     P   ++ + I++P+   ++Q  LS Q+ LGV+
Sbjct: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQ-WLSQQSDLGVI 189

Query: 190 PLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEK 249
             ++ +     +G W I+    +   Q +   F+V EYVLP FEV ++     Y   N K
Sbjct: 190 SKTFQLSSHPILGDWSIQVQVND---QTYYQSFQVSEYVLPKFEVTLQ--TPLYCSMNSK 244

Query: 250 GLEVTITARFLYGKKVEGTAFVIF-GIQDGEQRISLPESLKRIPIEDGSGEVVLS---RK 305
            L  TITA++ YGK V+G   + F  +    ++ ++ ++ K     +GS     +    K
Sbjct: 245 HLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFK----INGSANFSFNDEEMK 300

Query: 306 VLLDGVQNPRAE--DLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKY 363
            ++D   N  +E  DL         T +  S + + +   + +      Y I F      
Sbjct: 301 NVMDS-SNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTV 359

Query: 364 FKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQK----- 418
            KP + F   V VT  DG+   ++ +  +  + V ++TQ +     S +   +QK     
Sbjct: 360 LKPSLNFTATVKVTRADGN---QLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQ 416

Query: 419 PLSITV---RTKKQELSEAEQATRTMQALPYSTVGNSNNYLH---LSVLRTELR---PGE 469
            ++ TV    T K E    E ++  +Q   Y     S+  +H    S  +T ++     E
Sbjct: 417 KINYTVPQSGTFKIEFPILEDSSE-LQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDE 475

Query: 470 TLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSF 529
            + V     +  +   +++  +Y+++++G+L+  G+      Q+  +  L+    + P  
Sbjct: 476 NIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGK------QNSTMFSLTPENSWTPKA 529

Query: 530 RLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDH 589
            ++ YY         E+++D + + V+   V    +K   S+ +   P ++++L+I    
Sbjct: 530 CVIVYY----IEDDGEIISDVLKIPVQ--LVFKNKIKLYWSKVKAE-PSEKVSLRISVTQ 582

Query: 590 GARVV-LVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGL 644
              +V +VAVDK V ++N  N +T   +   +E  + G   G   +   VF + GL
Sbjct: 583 PDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638


>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
          Length = 1454

 Score =  219 bits (559), Expect = 1e-56
 Identities = 211/784 (26%), Positives = 359/784 (45%), Gaps = 105/784 (13%)

Query: 757  AEENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGIC 816
            AE++ V R  FPE+WLW++  +    K  +     ++ + D+IT W+ ++   S  +G  
Sbjct: 724  AEDSQV-RQYFPETWLWDLFPIGNSGKEAV-----HVTVPDAITEWKAMSFCTSQSRGFG 777

Query: 817  VADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAF---- 872
            ++    +T  + FF+DL LPYSVVR E   + A ++NY ++  ++V+ +L  +  +    
Sbjct: 778  LSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDC-IRVQTDLAKSHEYQLES 836

Query: 873  --------CSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFI--- 921
                    C  A   + H   +T     ++ + ++   + T + +          F+   
Sbjct: 837  WADSQTSSCLCADEAKTHHWNIT-----AVKLGHINFTISTKILDSNEPCGGQKGFVPQK 891

Query: 922  --SDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPD-TESET 978
              SD + K + V PEG+ + KT +       ++  E V  E   P D+   VPD T++  
Sbjct: 892  GRSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLE--LPVDI---VPDSTKAYV 946

Query: 979  RIL--LQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEK 1036
             +L  + GT +          + L  L+  PSGCGEQNM+   P +  + YL      EK
Sbjct: 947  TVLGDIMGTAL----------QNLDGLVQMPSGCGEQNMVLFAPIIYVLQYL------EK 990

Query: 1037 FGL---EKRQGALELIKKGYTQQLAFRQPSSAFAAFVKR--APSTWLTAYVVKVFSLAVN 1091
             GL   E R  A+  ++ GY ++L ++  + +++AF +R    +TWLTA+V K F  A  
Sbjct: 991  AGLLTEEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQK 1050

Query: 1092 LIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISL 1151
             I ID + +  A+KW+    Q P G +     ++H  M GG+    + +++LTA+V  +L
Sbjct: 1051 FIFIDPKNIQDALKWM-AGNQLPSGCYANVGNLLHTAMKGGV----DDEVSLTAYVTAAL 1105

Query: 1152 QE-AKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAG---------YALAQMGR 1201
             E  KD+ +  V+     +  +       Y     +Y  ++AG           L Q   
Sbjct: 1106 LEMGKDVDDPMVSQGLRCLKNSATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAI 1165

Query: 1202 LKGPLL--NKFLTTAKDKNRWEDPGKQLYNVEATSYALLA-----LLQLKDFDFVPPVVR 1254
            + G  +  ++  T + + + W +P     +VE T+YALLA      L  K+      +V 
Sbjct: 1166 ISGESIYWSQKPTPSSNASPWSEPA--AVDVELTAYALLAQLTKPSLTQKEIAKATSIVA 1223

Query: 1255 WLNEQRYYGGGYGSTQATFMVFQALAQYQKDA-PDHQELNLDVSLQLPSRSSKITHRIHW 1313
            WL +QR   GG+ STQ T +  QALA+Y   A    +E+NL V       +       + 
Sbjct: 1224 WLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINLVV-----KSTENFQRTFNI 1278

Query: 1314 ESAS-LLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTI-KPAP 1371
            +S + L+  ++T  N     T E  GQG + V T+             F L V I K   
Sbjct: 1279 QSVNRLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARC 1338

Query: 1372 ETEKRPQDAKNTMILEICTRYRGDQDAT-MSILDISMMTGFAPDTDDLKQLANGVDRYIS 1430
            E    P+    ++ L I T Y G + ++ M+I+++ M++GF+P          G ++ + 
Sbjct: 1339 EQPTSPR----SLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSP--------MEGTNQLLL 1386

Query: 1431 KYELDKAFS-DRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESC 1489
            +  L K      +TL IYLD++         F + Q   V  ++P  +KVY YY  +E  
Sbjct: 1387 QQPLVKKVEFGTDTLNIYLDELI-KNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQA 1445

Query: 1490 TRFY 1493
            T  Y
Sbjct: 1446 TIQY 1449



 Score =  105 bits (262), Expect = 4e-22
 Identities = 160/654 (24%), Positives = 272/654 (41%), Gaps = 90/654 (13%)

Query: 9   LLLLLLTHLP-LALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH--DFPGK 65
           LLL +L   P +A   P Y +  P  L   S + + L+      DV  TVT+   D   K
Sbjct: 5   LLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQK 64

Query: 66  KLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQAT-FGTQVV---EKVV 121
            L  S  K        H+  ++F +P         G  +  T++ +  G  +    +K V
Sbjct: 65  LLEYSGLKK------RHLHCISFLVPP-----PAGGTEEVATIRVSGVGNNISFEEKKKV 113

Query: 122 LVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVG-RTVMVNIENPEGIPVKQDSL 180
           L+  Q    F+QTDK +YTPG  V +RI T++   +PV  +  MV +++P    + Q  L
Sbjct: 114 LIQRQGNGTFVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQ-WL 172

Query: 181 SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEV-IVEPT 239
               + G++ LS+ +     +G + +      +  + F T F V+EYVLP F+V +VEP 
Sbjct: 173 EVVPEQGIVDLSFQLAPEAMLGTYTVAV----AEGKTFGT-FSVEEYVLPKFKVEVVEPK 227

Query: 240 EKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGE------QRISLPESLKRIPI 293
           E       ++   V I  R+ YGK + G   V    +         +R  LP+  + +  
Sbjct: 228 ELSTV---QESFLVKICCRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNL-- 282

Query: 294 EDGSGEVVLSRKVLLDGVQNPRAEDLVG----KSLYVSATVILHSGSDMVQAERSGIPIV 349
              SG+    +        +    DL+G      + + ATV+   G+ +       I I 
Sbjct: 283 ---SGQT--DKTGCFSAPVDMATFDLIGYAYSHQINIVATVV-EEGTGVEANATQNIYIS 336

Query: 350 TSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGS-----PAYRVPVAVQGEDTVQSLTQGD 404
                + F  T  ++ P  PF   + V   D S       + V     G      +T  +
Sbjct: 337 PQMGSMTFEDTSNFYHPNFPFSGKIRVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNN 396

Query: 405 GVAKLSINTHP-SQKPLSITVRTKKQEL-SEAEQATRTMQALPYSTVGNSNNYLHLSVLR 462
           G+A  ++ T   +   +S+  + + ++L    EQ  R  Q          N YLHL    
Sbjct: 397 GLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQ----------NAYLHLRPFY 446

Query: 463 TELRPGETLN-VNFLLRMDRAHEAKIRYY--------------TYLIMNKGRLLKAGRQ- 506
           +  R    ++ +N  L+  +  E  + YY              +Y ++ KG L+  G++ 
Sbjct: 447 STTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEGQKH 506

Query: 507 ---VREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSL 563
               ++  +    L L+ T+   P   LV Y   I  SG   VVAD +   V + C  + 
Sbjct: 507 LNSKKKGLKASFSLSLTFTSRLAPDPSLVIY--AIFPSG--GVVADKIQFSV-EMCFDN- 560

Query: 564 VVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIW 617
            V  G S  +Q +PG ++ L+++   G+   L AVD+ V +L    +L+   ++
Sbjct: 561 QVSLGFSPSQQ-LPGAEVELQLQAAPGSLCALRAVDESVLLLRPDRELSNRSVY 613


>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
          Length = 1428

 Score =  216 bits (549), Expect = 2e-55
 Identities = 208/783 (26%), Positives = 353/783 (45%), Gaps = 98/783 (12%)

Query: 764  RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGI-CVADPFE 822
            R  FPE+W+W   ++          +   + + DSIT+W      +S+  G+     P E
Sbjct: 687  RKHFPETWIWLDTNMGYR-----IYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVE 741

Query: 823  VTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNY-RQNQELKVRVELLHNPAFCSLATTKR- 880
            +   Q FFI L LPYSV+R E+  +   ++NY +   E+KV +E   +  F  L T+   
Sbjct: 742  LQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIE--KSDKFDILMTSNEI 799

Query: 881  ---RHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIR 937
                HQQT+ +P +   +V + I P  T L E+ +         SD V + + V  EGI 
Sbjct: 800  NATGHQQTLLVPSEDGATVLFPIRP--THLGEIPITVTALSPTASDAVTQMILVKAEGIE 857

Query: 938  MNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
             + + ++  LD      +   K       LS   P         +Q T +  +   +++ 
Sbjct: 858  KSYSQSI-LLDLTDNRLQSTLK------TLSFSFPPNTVTGSERVQITAIGDVLGPSING 910

Query: 998  ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
              L  LI  P GCGEQNMI   P +  + YL + +Q      EK   AL  +++GY ++L
Sbjct: 911  --LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEK---ALSFMRQGYQREL 965

Query: 1058 AFRQPSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPD 1115
             +++   +F+AF    P  STWL+A+V++ F  A   I ID  VL     WL    QK +
Sbjct: 966  LYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWL-KGHQKSN 1024

Query: 1116 GVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDF 1175
            G F +   VIH E+ GG    N+  + LTA+++ SL   +   + Q N     + ++  F
Sbjct: 1025 GEFWDPGRVIHSELQGG----NKSPVTLTAYIVTSLLGYR---KYQPNI---DVQESIHF 1074

Query: 1176 LEANY-MNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNR----WEDPGKQL--- 1227
            LE+ +   +  +YT+A+  YAL+ +G  K       LT   ++      W     +L   
Sbjct: 1075 LESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDS 1134

Query: 1228 -----YNVEATSYALLA-LLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQ 1281
                  ++E  +YALL+  LQ +  + + P++RWL+ QR   GG+ STQ T +  +AL++
Sbjct: 1135 WQPRSLDIEVAAYALLSHFLQFQTSEGI-PIMRWLSRQRNSLGGFASTQDTTVALKALSE 1193

Query: 1282 YQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGT 1341
            +     + +  N+ V++  PS  S +                  +     ++A G G   
Sbjct: 1194 FAA-LMNTERTNIQVTVTGPSSPSPLA---------------VVQPTAVNISANGFGFAI 1237

Query: 1342 LSVVTMYHAKAKDQLTCNK-------FDLKVTIKPAPETEKRPQDAKNTMILEICTRYRG 1394
              +  +Y+ KA       +       FDL V +       K  +D  N + L +CT + G
Sbjct: 1238 CQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV-------KENKDDLNHVDLNVCTSFSG 1290

Query: 1395 DQDATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHS 1454
               + M+++++++++GF   ++     A  +   + K E      D   L +YLD V+ +
Sbjct: 1291 PGRSGMALMEVNLLSGFMVPSE-----AISLSETVKKVEY-----DHGKLNLYLDSVNET 1340

Query: 1455 EDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRD-ELCRC 1513
            +  C+     + F V   Q  +V +  YY       R Y+ E +    + LC D + CR 
Sbjct: 1341 Q-FCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCD-LCSDVQGCRP 1398

Query: 1514 AEE 1516
             E+
Sbjct: 1399 CED 1401



 Score =  104 bits (260), Expect = 6e-22
 Identities = 127/536 (23%), Positives = 240/536 (44%), Gaps = 49/536 (9%)

Query: 130 LFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVL 189
           +FIQTDK +Y P   V +RI T+     P   ++ + I++P+   ++Q  LS Q+ LGV+
Sbjct: 131 VFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQ-WLSQQSDLGVI 189

Query: 190 PLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEK 249
             ++ +     +G W I+    +   Q +   F+V EYVLP FEV ++     Y   N K
Sbjct: 190 SKTFQLSSHPILGDWSIQVQVND---QTYYQSFQVSEYVLPKFEVTLQ--TPLYCSMNSK 244

Query: 250 GLEVTITARFLYGKKVEGTAFVIF-GIQDGEQRISLPESLKRIPIEDGSGEVVLS---RK 305
            L  TITA++ YGK V+G   + F  +    ++ ++ ++ K     +GS     +    K
Sbjct: 245 HLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFK----INGSANFSFNDEEMK 300

Query: 306 VLLDGVQNPRAE--DLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKY 363
            ++D   N  +E  DL         T +  S + + +   + +      Y I F      
Sbjct: 301 NVMDS-SNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTV 359

Query: 364 FKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQK----- 418
            KP + F   V VT  DG+   ++ +  +  + V ++TQ +     S +   +QK     
Sbjct: 360 LKPSLNFTATVKVTRADGN---QLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQ 416

Query: 419 PLSITV---RTKKQELSEAEQATRTMQALPYSTVGNSNNYLH---LSVLRTELR---PGE 469
            ++ TV    T K E    E ++  +Q   Y     S+  +H    S  +T ++     E
Sbjct: 417 KINYTVPQSGTFKIEFPILEDSSE-LQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDE 475

Query: 470 TLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPSF 529
            + V     +  +   +++  +Y+++++G+L+  G+      Q+  +  L+    + P  
Sbjct: 476 NIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGK------QNSTMFSLTPENSWTPKA 529

Query: 530 RLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDH 589
            ++ YY         E+++D + + V+   V    +K   S+ +   P ++++L+I    
Sbjct: 530 CVIVYY----IEDDGEIISDVLKIPVQ--LVFKNKIKLYWSKVKAE-PSEKVSLRISVTQ 582

Query: 590 GARVV-LVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKDYAGVFSDAGL 644
              +V +VAVDK V ++N  N +T   +   +E  + G   G   +   VF + GL
Sbjct: 583 PDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGL 638


>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
          Length = 1474

 Score =  214 bits (544), Expect = 7e-55
 Identities = 200/769 (26%), Positives = 347/769 (45%), Gaps = 74/769 (9%)

Query: 764  RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEV 823
            R  FPE+W+W++  +     N      + + + D+IT W+  A  +S+  G+ ++    +
Sbjct: 732  RKYFPETWIWDLVVV-----NSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASL 786

Query: 824  TVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQ 883
               Q FF++L +PYSV+R E   ++A + NY   + ++V V+L  +PAF  LA    + Q
Sbjct: 787  RAFQPFFVELTMPYSVIRGEAFTLKATVLNYLP-KCIRVSVQLEASPAF--LAVPVEKEQ 843

Query: 884  QTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFISDGVRKSLKVVPEGIRMNKTVA 943
                I      +V + + P   G     V A         G    +  VPE  R +  + 
Sbjct: 844  APHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGT--EVPSVPEHGRKDTVIK 901

Query: 944  VRTLDPERLGREGVQKEDIPPA------DLSDQVPDTESETRILLQGTPVAQMTEDAVDA 997
               ++PE L +E      + P+      +LS ++P    E       + +  +   A+  
Sbjct: 902  PLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAM-- 959

Query: 998  ERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQL 1057
            +  ++L+  P GCGEQNM+   P +  + YL+ET+Q      E +  A+  +  GY +QL
Sbjct: 960  QNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTP---EIKSKAIGYLNTGYQRQL 1016

Query: 1058 AFRQPSSAFAAFVKR----APSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQK 1113
             ++    +++ F +R      +TWLTA+V+K F+ A   I ID   +  A+ WL  ++QK
Sbjct: 1017 NYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWL-SQRQK 1075

Query: 1114 PDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQV--NSL-----P 1166
             +G F+    +++  + GG+    E ++ L+A++ I+L E        V  N+L      
Sbjct: 1076 DNGCFRSSGSLLNNAIKGGV----EDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESA 1131

Query: 1167 GSITKAGDFLEANYMNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKNRWEDPGK- 1225
                + GD     Y     +Y  A+AG    +   LK   LN+      +   WE P K 
Sbjct: 1132 WKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKS--LNEEAVKKDNSVHWERPQKP 1189

Query: 1226 -----QLY-------NVEATSYALLALLQL------KDFDFVPPVVRWLNEQRYYGGGYG 1267
                   Y        VE TSY LLA L        +D      +V+W+ +Q+   GG+ 
Sbjct: 1190 KAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFS 1249

Query: 1268 STQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKEN 1327
            STQ T +   AL++Y             V++Q  S +     ++   +  LL+     E 
Sbjct: 1250 STQDTVVALHALSKYGAATFTRTGKAAQVTIQ-SSGTFSSKFQVDNNNRLLLQQVSLPEL 1308

Query: 1328 EG-FTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMIL 1386
             G +++   G+G   L     Y+   + +    +F   + ++  P+T   P+ A  +  +
Sbjct: 1309 PGEYSMKVTGEGCVYLQTSLKYNILPEKE----EFPFALGVQTLPQTCDEPK-AHTSFQI 1363

Query: 1387 EICTRYRGDQDAT-MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLI 1445
             +   Y G + A+ M+I+D+ M++GF P    +K L      ++S+ E+       N ++
Sbjct: 1364 SLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLER--SNHVSRTEVSS-----NHVL 1416

Query: 1446 IYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYH 1494
            IYLDKVS ++   L F V Q   V  ++P  VKVY YY  +E     Y+
Sbjct: 1417 IYLDKVS-NQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYN 1464



 Score =  138 bits (348), Expect = 4e-32
 Identities = 165/659 (25%), Positives = 287/659 (43%), Gaps = 62/659 (9%)

Query: 7   PSLLLLLLTHLPL---ALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFP 63
           PSL+LLLL  LP      G P Y ++ P++L  E+ E   +        V V+ ++    
Sbjct: 9   PSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVR 68

Query: 64  GKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEK--VV 121
           G + +     T L    + +  V F +P +    S      F+TVQ    TQ  +K   V
Sbjct: 69  GNRSLF----TDLEAENDVLHCVAFAVPKS----SSNEEVMFLTVQVKGPTQEFKKRTTV 120

Query: 122 LVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTV-MVNIENPEGIPVKQDSL 180
           +V  +   +F+QTDK+IY PG TV +R+ +++    P+   + +V I++P+G  + Q   
Sbjct: 121 MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQ- 179

Query: 181 SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
           S Q + G+   S+ +      G +K+    ++  +      F V+E+VLP FEV V    
Sbjct: 180 SFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRT--EHPFTVEEFVLPKFEVQV-TVP 236

Query: 241 KFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEV 300
           K   I  E+ + V++   + YGK V G   V    +  +      E  +    E  SG++
Sbjct: 237 KIITILEEE-MNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAF-CEKFSGQL 294

Query: 301 ----VLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQIH 356
                  ++V     Q  R E      L+  A  I   G+ +    R    I  +  ++ 
Sbjct: 295 NSHGCFYQQVKTKVFQLKRKE--YEMKLHTEAQ-IQEEGTVVELTGRQSSEITRTITKLS 351

Query: 357 FTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDT---VQSLTQGDGVAKLSINT 413
           F K   +F+ G+PF   V + +  G P     + ++G +      + T   G+ + SINT
Sbjct: 352 FVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINT 411

Query: 414 HPSQKPLSITVRTKKQELS----------EAEQATRTMQALPYSTVGNSNNYLHLSVLRT 463
             +    S+TVR   ++ S          E E+A  T     Y     S +++HL  +  
Sbjct: 412 -TNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHT----AYLVFSPSKSFVHLEPMSH 466

Query: 464 ELRPG--ETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAG------RQVREPGQDLV 515
           EL  G  +T+  +++L        K   + YLIM KG +++ G      +Q    G   +
Sbjct: 467 ELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSI 526

Query: 516 VLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQP 575
            +P  + +D  P  RL+ Y  L       +V+ DS   DV ++C+ + V  S      Q 
Sbjct: 527 SIP--VKSDIAPVARLLIYAVL----PTGDVIGDSAKYDV-ENCLANKVDLS--FSPSQS 577

Query: 576 VPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGKD 634
           +P     L++     +   L AVD+ V ++    +L+ S +++++ + D+   PG   D
Sbjct: 578 LPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLND 636


>gi|162809334 pregnancy-zone protein [Homo sapiens]
          Length = 1482

 Score =  202 bits (514), Expect = 2e-51
 Identities = 198/782 (25%), Positives = 350/782 (44%), Gaps = 102/782 (13%)

Query: 764  RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEV 823
            RS FPE+W+W +  +     N      + + + D+IT W+  A  +S+  G+ ++    +
Sbjct: 738  RSYFPETWIWELVAV-----NSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASL 792

Query: 824  TVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQ 883
               Q FF++L +PYSV+R E   ++A + NY   + ++V V+L  +PAF +   TK    
Sbjct: 793  RAFQPFFVELTMPYSVIRGEVFTLKATVLNYLP-KCIRVSVQLKASPAFLASQNTKGEES 851

Query: 884  QTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHF--------------ISDGVRKSL 929
              +    + +LS  + + P   G     V A                      D V K+L
Sbjct: 852  YCICGNERQTLS--WTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTL 909

Query: 930  KVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQ 989
             V  EGI   KT +  T         G    +     LS ++P    +       + +  
Sbjct: 910  LVEAEGIEQEKTFSSMTC------ASGANVSE----QLSLKLPSNVVKESARASFSVLGD 959

Query: 990  MTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELI 1049
            +   A+  + +++L+  P GCGEQNM+   P +  ++YL+ET+Q  +   E +  A+  +
Sbjct: 960  ILGSAM--QNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQ---EIKAKAVGYL 1014

Query: 1050 KKGYTQQLAFRQPSSAFAAFVKR----APSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVK 1105
              GY +QL ++    +++ F +R      +TWLTA+V+K F+ A + I ID   +  ++ 
Sbjct: 1015 ITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLT 1074

Query: 1106 WLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQE-----AKDICEE 1160
            WL  + QK +G F+    +++  + GG+    E +  L+A+V I+L E        I   
Sbjct: 1075 WL-SQMQKDNGCFRSSGSLLNNAIKGGV----EDEATLSAYVTIALLEIPLPVTNPIVRN 1129

Query: 1161 QVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKN-- 1218
             +  L  +   A +    +++     YT A+  YA + +G+      N+ +  + DK   
Sbjct: 1130 ALFCLESAWNVAKEGTHGSHV-----YTKALLAYAFSLLGKQN---QNREILNSLDKEAV 1181

Query: 1219 ------RWEDPGK------QLY-------NVEATSYALLALLQLK------DFDFVPPVV 1253
                   WE P +       LY        VE TSY LLA L  +      D      +V
Sbjct: 1182 KEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIV 1241

Query: 1254 RWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHW 1313
            +W+ +Q+   GG+ STQ T +   AL++Y        E    V++Q  S++     ++  
Sbjct: 1242 KWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVTVQ-DSQTFSTNFQVDN 1300

Query: 1314 ESASLLRSEETKENEG-FTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPE 1372
             +  LL+     E  G + +T  G+    L     Y+   + +   + F LKV  +  P+
Sbjct: 1301 NNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNILPEKE--DSPFALKV--QTVPQ 1356

Query: 1373 TEKRPQDAKNTMILEICTRYRGDQDAT-MSILDISMMTGFAPDTDDLKQLANGVDRYISK 1431
            T      A  +  + +   Y G++ A+ M I+D+ M++GF P    +K L       +S+
Sbjct: 1357 T-CDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSS--VSR 1413

Query: 1432 YELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTR 1491
             E+       N ++IY+++V+ ++    +F V Q   V  ++P  VKVY YY  +ES   
Sbjct: 1414 TEV-----SNNHVLIYVEQVT-NQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVA 1467

Query: 1492 FY 1493
             Y
Sbjct: 1468 EY 1469



 Score =  116 bits (291), Expect = 2e-25
 Identities = 156/650 (24%), Positives = 272/650 (41%), Gaps = 72/650 (11%)

Query: 9   LLLLLLTHLPLALGSPMYSIITPNILRLES-EETMVLEAHDAQGDVPVTVTVHDFPGKKL 67
           LLL+LL+        P Y ++ P++L  E+ ++  VL +H     +  TVTV        
Sbjct: 13  LLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSH-----LNETVTVSASLESGR 67

Query: 68  VLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEK--VVLVSL 125
              S  T L    +    V+FT+P      S      F+++Q    TQ   K   VLV  
Sbjct: 68  ENRSLFTDLVAEKDLFHCVSFTLPRI----SASSEVAFLSIQIKGPTQDFRKRNTVLVLN 123

Query: 126 QSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTV-MVNIENPEGIPVKQDSLSSQN 184
               +F+QTDK +Y PG TV +R+ +V+    P    + ++ +ENP    + Q   S + 
Sbjct: 124 TQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQ-SLKL 182

Query: 185 QLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYY 244
           + G+  LS+ +      G +++    E+  +      F V+E+VLP FEV V+   K   
Sbjct: 183 EAGINQLSFPLSSEPIQGSYRVVVQTESGGR--IQHPFTVEEFVLPKFEVKVQ-VPKIIS 239

Query: 245 IYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSR 304
           I +EK + +T+   + YGK V G A V           SL   L R+   D        +
Sbjct: 240 IMDEK-VNITVCGEYTYGKPVPGLATV-----------SLCRKLSRVLNCD-------KQ 280

Query: 305 KVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDM-------VQAERSGIPIVTSPY---- 353
           +V  +  Q   +   + + ++     I ++G +M       ++ E + + +  +      
Sbjct: 281 EVCEEFSQQLNSNGCITQQVHTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEIT 340

Query: 354 ----QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDT---VQSLTQGDGV 406
               ++ F K   +F+ G+PF   V + +  G P       +   D      + T   G+
Sbjct: 341 NIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFISVNDANYYSNATTNEQGL 400

Query: 407 AKLSINTHP-SQKPLSITVRTKKQEL----SEAEQATRTMQALPYSTVGNSNNYLHLSVL 461
           A+ SINT   S   L + V T    L    S   +  +  Q         S +Y+HL  +
Sbjct: 401 AQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPV 460

Query: 462 RTELRPG--ETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVR--EPG--QDLV 515
              L  G  ET+  ++ L      E     + YLIM KG ++++G      E G  +   
Sbjct: 461 AGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSF 520

Query: 516 VLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQP 575
            L   + +D  P  R+  +  L       EVV DS   ++ ++C+ + V  S      Q 
Sbjct: 521 ALSFPVESDVAPIARMFIFAIL----PDGEVVGDSEKFEI-ENCLANKVDLS--FSPAQS 573

Query: 576 VPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADI 625
            P     L++     +   L AVD+ V ++  + +L+ S +++++   D+
Sbjct: 574 PPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDL 623


>gi|239758130 PREDICTED: similar to complement component 4B (Childo
            blood group), partial [Homo sapiens]
          Length = 666

 Score =  200 bits (509), Expect = 8e-51
 Identities = 181/674 (26%), Positives = 286/674 (42%), Gaps = 101/674 (14%)

Query: 1079 TAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNE 1138
            TA+V+KV SLA   +    + L     WL L +Q+ DG FQ+ +PVIH+ M GGL  N+E
Sbjct: 1    TAFVLKVLSLAQEQVGGSREKLQETSNWL-LSQQQADGSFQDLSPVIHRSMQGGLVGNDE 59

Query: 1139 KDMALTAFVLISLQEAKDICEEQ-----VNSLPGSITKAGDFL-EANYMNLQRSYTVAIA 1192
              +ALTAFV I+L     + +++        +  SI+KA  FL E     L  ++  AI 
Sbjct: 60   T-VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAIT 118

Query: 1193 GYALAQM---GRLKGPLLNKFLTTAK---DKNRW--------------------EDPGKQ 1226
             YAL        L+G   N  +  A+   D   W                     DP  Q
Sbjct: 119  AYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQ 178

Query: 1227 LYN--VEATSYALLALLQLKD-FDFVPPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQ 1283
                 +E T+YALL LL  +   +       WL  Q  + GG+ STQ T +   AL+ Y 
Sbjct: 179  APALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYW 238

Query: 1284 KDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKE---NEGFTVTAEGKGQG 1340
              +   +E  L+V+L    R+   +H +   +  +   EE  +        V   G  +G
Sbjct: 239  IASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKG 298

Query: 1341 TLSVVTMYHAKAKDQLTCNKFDLKVTIK---------------------PAPETEKRPQD 1379
            TL V+  Y+       TC    ++VT+K                     PA +    P  
Sbjct: 299  TLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQ 358

Query: 1380 AKNTMILEICTRYRGDQDAT--------------------------MSILDISMMTGFAP 1413
                + L    R R  ++A                           M+I D+++++GF  
Sbjct: 359  PVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHA 418

Query: 1414 DTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQ 1473
               DL++L +  DRY+S +E +        +++Y D V  S + C+ F+  Q   V L+Q
Sbjct: 419  LRADLEKLTSLSDRYVSHFETEGPH-----VLLYFDSVPTSRE-CVGFEAVQEVPVGLVQ 472

Query: 1474 PGAVKVYAYYNLEESCTRFYHPEKEDGKLNKLCRDELCRCAEENCFIQKSDDKVTLEE-- 1531
            P +  +Y YYN E  C+ FY    +   L  LC  E+C+CAE  C  Q+   +  L++  
Sbjct: 473  PASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDED 532

Query: 1532 --RLDKAC-EPGVDYVYKTRLVKVQLSNDFDEYIMAIEQTIKSGSD-EVQVGQQRTFISP 1587
              R+  AC  P V+Y ++ ++++      F  +   I Q +    D +    Q R F+  
Sbjct: 533  GYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVR 592

Query: 1588 IKCREALKLEEKKHYLMWGLSSDFWGEKPNLSYIIGKDTWVEHWPEEDECQDEENQKQCQ 1647
              CR  L+LE  K YL+ GL    +  + +  Y++  ++W+E  P E  C+    +  C 
Sbjct: 593  ASCR--LRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACA 650

Query: 1648 DLGAFTESMVVFGC 1661
             L  F +     GC
Sbjct: 651  QLNDFLQEYGTQGC 664


>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
            8 [Homo sapiens]
          Length = 1932

 Score =  183 bits (464), Expect = 1e-45
 Identities = 156/569 (27%), Positives = 256/569 (44%), Gaps = 74/569 (13%)

Query: 1000 LKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAF 1059
            L +L+  P GCGEQNMI   P V  + YL +T+Q      E  +   + + +GY +QL +
Sbjct: 1181 LNNLLRLPFGCGEQNMIHFAPNVFVLKYLQKTQQLSP---EVERETTDYLVQGYQRQLTY 1237

Query: 1060 RQPSSAFAAFVKR--APSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGV 1117
            ++   +++AF +R  + S WLTA+V+K F+ A + I +D + L  A  W+I ++Q+ DG 
Sbjct: 1238 KRQDGSYSAFGERDASGSMWLTAFVLKSFAQARSFIFVDPRELAAAKSWII-QQQQADGS 1296

Query: 1118 FQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLE 1177
            F     V+++++ GG+       + LTA+V+++L E     EE+     GS  KA  FLE
Sbjct: 1297 FLAVGRVLNKDIQGGIHGT----VPLTAYVVVALLETGTASEEE----RGSTDKARHFLE 1348

Query: 1178 ANYMNLQRSYTVAIAGYALAQMGRLKGP----------LLNKFLTTAKDKNRWE-DPGKQ 1226
            +        Y+ A+  YAL  +     P          ++   +T     N W+ D G  
Sbjct: 1349 SAAPLAMDPYSCALTTYALTLLRSPAAPEALRKLRSLAIMRDGVTHWSLSNSWDVDKGTF 1408

Query: 1227 LY------------NVEATSYALLALLQLKDFDFVPPVVRWLNEQRYYGGGYGSTQATFM 1274
            L              VE T+YALL    L D     PVV+WL++QR   GG+ STQ T +
Sbjct: 1409 LSFSDRVSQSVVSAEVEMTAYALLTYTLLGDVAAALPVVKWLSQQRNALGGFSSTQDTCV 1468

Query: 1275 VFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHWESASLLRSEETKE-NEGFTVT 1333
              QALA+Y         +NL VSL   +   + T  +H  +  +L++        G  V+
Sbjct: 1469 ALQALAEYAI-LSYAGGINLTVSLASTNLDYQETFELHRTNQKVLQTAAIPSLPTGLFVS 1527

Query: 1334 AEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRP---------------- 1377
            A+G G   + +   Y+    D +    F L V+++  PE + RP                
Sbjct: 1528 AKGDGCCLMQIDVTYNVP--DPVAKPAFQLLVSLQE-PEAQGRPPPMPASAAEGSRGDWP 1584

Query: 1378 -----------QDAKNTMILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVD 1426
                          +  ++LE+CTR+     + M++L++ +++GF  D + L+QL     
Sbjct: 1585 PADDDDPAADQHHQEYKVMLEVCTRWLHAGSSNMAVLEVPLLSGFRADIESLEQLLLDKH 1644

Query: 1427 RYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLE 1486
              + +YE+         ++ Y D++      C+ F+  +   V       V VY YY   
Sbjct: 1645 MGMKRYEV-----AGRRVLFYFDEIPSRCLTCVRFRALRECVVGRTSALPVSVYDYYEPA 1699

Query: 1487 ESCTRFYHPEKEDGKLNKLCRDELCRCAE 1515
               TRFY+         +LC    C   E
Sbjct: 1700 FEATRFYNVSTHSPLARELCAGPACNEVE 1728



 Score =  119 bits (299), Expect = 2e-26
 Identities = 166/690 (24%), Positives = 275/690 (39%), Gaps = 86/690 (12%)

Query: 7   PSLLLLLLTHLPLALGSPM---YSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFP 63
           P LLLLL     +    P    Y I  P++ R   EE + +   ++  +V V        
Sbjct: 58  PLLLLLLSARDGVRAAQPQAPGYLIAAPSVFRAGVEEVISVTIFNSPREVTVQA------ 111

Query: 64  GKKLVLSSEKTVLTP-ATNHMGNVTFTIPAN---REFKSEKGRNKFVTVQATFGTQVVEK 119
             +LV   E  V +  A    G +   +P     +      GR         F  Q    
Sbjct: 112 --QLVAQGEPVVQSQGAILDKGTIKLKVPTGLRGQALLKVWGRGWQAEEGPLFHNQTS-- 167

Query: 120 VVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDS 179
            V V  +   +FIQTDK +Y P   VL  IFTV+  L PV   +   I +P G  + +  
Sbjct: 168 -VTVDGRGASVFIQTDKPVYRPQHRVLISIFTVSPNLRPVNEKLEAYILDPRGSRMIEWR 226

Query: 180 LSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPT 239
                  G+  +S+ + +   +G+W I   +       ++  FEV++YVLP FE++++P 
Sbjct: 227 HLKPFCCGITNMSFPLSDQPVLGEWFI---FVEMQGHAYNKSFEVQKYVLPKFELLIDPP 283

Query: 240 EKFYYIYNEKGLEV-TITARFLYGKKVEGTAFV---IFGIQDGEQRISLPESLKRIPIED 295
               YI +    E  T+ AR+ +GK V G   +   + G+      +  P       +  
Sbjct: 284 R---YIQDLDACETGTVRARYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLRTTKILGS 340

Query: 296 GSGEVVLSRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAERSGIPIVTSPYQI 355
              ++ +   +  D  ++ R        + + A V    GS  V  + S  P+      I
Sbjct: 341 RDFDICVRDMIPADVPEHFRGR------VSIWAMVTSVDGSQQVAFDDS-TPVQRQLVDI 393

Query: 356 HFTK-TPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDT------VQSLTQGDGVAK 408
            ++K T K FKPG+ +   V ++ PDGSPA  V V ++ E T         +    G+  
Sbjct: 394 RYSKDTRKQFKPGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYTSEVVSQRGLVG 453

Query: 409 LSINTHPSQKPLSITVRTKKQELSEAEQATRTMQALPYSTVGN----SNNYLHLSVLRTE 464
             I + P+     + + TK   L+      + + +  Y ++G+    S  YL L      
Sbjct: 454 FEIPSIPTSAQ-HVWLETKVMALNGKPVGAQYLPS--YLSLGSWYSPSQCYLQLQPPSHP 510

Query: 465 LRPGE--------TLNVNFLLRMDRAHEAKI---------------RYYTYLIMNKGRLL 501
           L+ GE        T   NF L  + A    I               +     +    RL 
Sbjct: 511 LQVGEEAYFSVKSTCPCNFTLYYEVAARGNIVLSGQQPAHTTQQRSKRAAPALEKPIRLT 570

Query: 502 KAGRQVREPGQDLVV------LPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDV 555
                   P  +  V      L L++T   +P  RL+ +Y      G    VADS+   V
Sbjct: 571 HLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEG----VADSLQFAV 626

Query: 556 KDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSK 615
           +      + V    +E +   PG+ + L+I    G+ V + AVDK V++L    +LT ++
Sbjct: 627 ETFFENQVSVTYSANETQ---PGEVVDLRIRAARGSCVCVAAVDKSVYLLRSGFRLTPAQ 683

Query: 616 IWDVVEKADIGCTPGSGKDYAGVFSDAGLT 645
           ++  +E  D+  + G  ++  G F  AGLT
Sbjct: 684 VFQELEDYDVSDSFGVSRE-DGPFWWAGLT 712



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 43/155 (27%), Positives = 80/155 (51%), Gaps = 6/155 (3%)

Query: 764 RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEV 823
           R+ FPE+W+W+  ++ +P   G     +++ + DSIT+W   AV++S  +G+ +A+P  +
Sbjct: 791 RTFFPETWIWHCLNISDPSGEGT----LSVKVPDSITSWVGEAVALSTSQGLGIAEPSLL 846

Query: 824 TVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQN-QELKVRVELLHNPAFCSLATTKRRH 882
              + FF+D  LP  ++R EQV+I   +YNY     E+ +++ +     F      KR  
Sbjct: 847 KTFKPFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFVG-HPGKRHV 905

Query: 883 QQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVY 917
            + + + P  +  +  V+     GL  +  KA  Y
Sbjct: 906 TKKMCVAPGEAEPIWVVLSFSDLGLNNITAKALAY 940


>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
          Length = 1353

 Score =  173 bits (439), Expect = 1e-42
 Identities = 309/1440 (21%), Positives = 565/1440 (39%), Gaps = 218/1440 (15%)

Query: 105  FVTVQATFGTQVVEKVVLVSLQS--GYLFIQTDKTIYTPGSTVLYRI--FTVNHKLLPVG 160
            F+T  A   T  +E+   V+++S    +F+QTDK  Y PG   +  I  F ++       
Sbjct: 34   FITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIAQFFLDTYTFTYP 93

Query: 161  RTVMVNIENPEGIPVKQDSLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFST 220
               + + +N   I  +Q+  S +N   +  LS+ +      G + I    + + ++  + 
Sbjct: 94   NITLKDPQNNR-IFQRQNVTSFRN---ITQLSFQLISEPMFGDYWI--VVKRNSRETVTH 147

Query: 221  EFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFV-----IFGI 275
            +F VK YVLP FEV V   +      +E   +V + A++ +G+ V+G   +      F  
Sbjct: 148  QFAVKRYVLPKFEVTVNAPQTVTISDDE--FQVDVCAKYNFGQPVQGETQIRVCREYFSS 205

Query: 276  QDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNPRAEDLVGKSLYVS---ATVIL 332
             + E+  +         +E+G    +++ KV            L    L+++   A ++ 
Sbjct: 206  SNCEKNENEICEQFIAQLENGCVSQIVNTKVF----------QLYRSGLFMTFHVAVIVT 255

Query: 333  HSGSD---MVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPV 389
             SG+    M  +E++ + I      ++F     +++ G+ +   +  ++P+  P     +
Sbjct: 256  ESGTGNYFMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLL 315

Query: 390  AVQGEDTV--QSLTQGDGVAKLSINTHPSQKPLSITVRTKKQELSEAEQATRTMQALPYS 447
             ++  D       T  +G A+ SI+T     P      T  +  S    +  T Q L   
Sbjct: 316  QLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAH 375

Query: 448  TV-----GNSNNYLHL--SVLRTELRPGETLNVNFLLRMDRAHE---AKIRYYTYLIMNK 497
             +       +N++L +     + E    + + V++ L  +   +    K  Y   L  + 
Sbjct: 376  FLVSRFYSRTNSFLKIVPEPKQLECNQQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSHDS 435

Query: 498  GRLLK--AGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDV 555
            G      +   +          P+SI+ D  P+  L  Y   +  SG  E+VADSV   V
Sbjct: 436  GNFQHRISSSPIYTAWNGNFSFPISISADLAPAAVLFVY--TLHPSG--EIVADSVRFQV 491

Query: 556  KDSCVGSLVVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSK 615
             D C    V     +E  Q +PG   +L ++        L AVD+ V +L  + +L+   
Sbjct: 492  -DKCFKHKVNIKFSNE--QGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAES 548

Query: 616  IWDVVEKA------------DIG----CTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAE 659
            ++++V               D G    C P     Y G++      +         +   
Sbjct: 549  VYNMVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMG 608

Query: 660  LQCPQPAARRRRSVQLTEKRMDKVGKYPKELRKCCED--GMRENPMRFSCQRRTRFISLG 717
            L+       R+  V + E+R+      PK L    E+   MR  P R +C+        G
Sbjct: 609  LKVFTNLHYRKPEVCVMERRLP----LPKPLYLETENYGPMRSVPSRIACR--------G 656

Query: 718  EACKKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVS--RSEFPESWLWNV 775
            E    V                                  E+ I+   R+ FPE+W+W  
Sbjct: 657  ENADYV----------------------------------EQAIIQTVRTNFPETWMW-- 680

Query: 776  EDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRL 835
             DL     +G +   ++  + D+IT WE     ++   G  ++    + V Q FFI++  
Sbjct: 681  -DLVSVDSSGSAN--LSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFFIEIAS 737

Query: 836  PYSVVRNEQVEIRAVLYNYRQN-QELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSL 894
            P+SVV+NEQ ++   +++YR    E+ V+VE   N    ++ T K    + +    +   
Sbjct: 738  PFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYE-ANIHTLKINGSEVIQAGGRK-- 794

Query: 895  SVPYVIVPLKTGLQEVEVKAAVYHHFI-------------SDGVRKSLKVVPEGIRMNKT 941
            +  + I+P K G   + V A                     D V +S  V PEGI   +T
Sbjct: 795  TNVWTIIPKKLGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVQSFLVEPEGIEKERT 854

Query: 942  VAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLK 1001
             +        +  EG +       DL + V +  +     + G  +    ++ V      
Sbjct: 855  QSF------LICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLALQNLV------ 902

Query: 1002 HLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQ 1061
             ++  P G GEQN   +      + YL  TEQ  +   E +  A  L+  GY +QL+F+ 
Sbjct: 903  -VLQMPYGSGEQNAALLASDTYVLDYLKSTEQLTE---EVQSKAFFLLSNGYQRQLSFKN 958

Query: 1062 PSSAFAAFVKRAP--STWLTAYVVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQ 1119
               +++ F +++   S  L+A   K        + ID  V    + WL   +QK  G F+
Sbjct: 959  SDGSYSVFWQQSQKGSIXLSALTFKTLERMKKYVFIDENVQKQTLIWL-SSQQKTSGCFK 1017

Query: 1120 EDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQEAKDICEEQVNSLPGSITKAGDFLEAN 1179
             D  + +    GG    +E+D++LTA+V+    EA       +N    ++  A   LEA 
Sbjct: 1018 NDGQLFNHAWEGG----DEEDISLTAYVVGMFFEA------GLNFTFPALRNALFCLEAA 1067

Query: 1180 Y-MNLQRSYTVAIAGYALAQMGRLK------------GPLLNKFLTTAKD-KNRWED--- 1222
                +   Y  AI  YA A  G+ K             P LN  +   ++ K + E+   
Sbjct: 1068 LDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSAPKLNNVIYWERERKPKTEEFPS 1127

Query: 1223 --PGKQLYNVEATSYALLALLQLK--DFDFVPPVVRWLNEQRYYGGGYGSTQA--TFMVF 1276
              P       E + Y LLA++  K  D  +   +V+WL ++    GG+ S Q     ++ 
Sbjct: 1128 FIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQRMNSHGGFSSNQVINVGLIL 1187

Query: 1277 QALAQYQKDAPDHQEL--NLDVSLQLPSRSSKITHRIHWESASLL-RSEETKENEGFTVT 1333
             A+   QK A   + L      ++   S  S    +++  +  L+ RSE T+    +TV 
Sbjct: 1188 IAICLMQKLARGEEGLFSKDQNTVTFSSEGSSEIFQVNGHNRLLVQRSEVTQAPGEYTVD 1247

Query: 1334 AEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYR 1393
             EG G   +     Y+     + +     L++              +     L +  +Y 
Sbjct: 1248 VEGHGCTFIQATLKYNVLLPKKASGFSLSLEIV----------KNYSSTAFDLTVTLKYT 1297

Query: 1394 GDQD-ATMSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVS 1452
            G ++ ++M ++D+ M++GF P    ++++ N              F  +++ I Y DK++
Sbjct: 1298 GIRNKSSMVVIDVKMLSGFTPTMSSIEEVNN----------RSLIFQHKDSYIEYKDKIN 1347


>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
          Length = 1394

 Score =  171 bits (433), Expect = 5e-42
 Identities = 326/1533 (21%), Positives = 591/1533 (38%), Gaps = 227/1533 (14%)

Query: 14   LTHLPLALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEK 73
            +T   L+  S  Y ++ P++L+  S +    +  +    V +TV+++    +  +     
Sbjct: 1    MTGSHLSHDSWQYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENV 60

Query: 74   TVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQS--GYLF 131
            T      N    ++F +P  R          F+T  A   T  +E+   V+++S    +F
Sbjct: 61   T----GENFFKCISFEVPQARSDPLA-----FITFSAKGATLNLEERRSVAIRSRENVVF 111

Query: 132  IQTDKTIYTPGSTVLYRI--FTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSSQNQLGVL 189
            +QTDK  Y PG   +  I  F ++          + + +N   I   Q+  S +N   + 
Sbjct: 112  VQTDKPTYKPGQKDVNGIAQFFLDTYTFTYPNITLKDPQNNR-IFQWQNVTSFRN---IT 167

Query: 190  PLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEK 249
             LS+ +      G + I    + + ++  + +F VK YVLP FEV V   +      +E 
Sbjct: 168  QLSFQLISEPMFGDYWI--VVKRNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDE- 224

Query: 250  GLEVTITARFLYGKKVEGTAFV-----IFGIQDGEQRISLPESLKRIPIEDGSGEVVLSR 304
              +V + A++ +G+ V+G   +      F   + E+  +         +E+G    +++ 
Sbjct: 225  -FQVDVCAKYTFGQPVQGKTQIRVCREYFSSSNCEKNDNEICEQFIAQLENGCVSQIVNT 283

Query: 305  KVLLDGVQNPRAEDLVGKSLYVS---ATVILHSGSD---MVQAERSGIPIVTSPYQIHFT 358
            KV            L    L+++   A ++   G+    M  +E++ + I      ++F 
Sbjct: 284  KVF----------QLYRSGLFMTFHVAVIVTEFGTGNYCMQISEKTSVFITQLLGTVNFE 333

Query: 359  KTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDTV--QSLTQGDGVAKLSINTHPS 416
                +++ G+ +   +  ++P+  P     + ++  D       T  +G A+ SI+T   
Sbjct: 334  NMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDI 393

Query: 417  QKP---LSITVRTKKQELSEAEQATRTMQA--LPYSTVGNSNNYLHL--SVLRTELRPGE 469
              P   L  T    K     +    + + A  L       +N++L +     + E    +
Sbjct: 394  FDPEFNLKATYVRPKSCYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQK 453

Query: 470  TLNVNFLLRMDRAHE---AKIRYYTYLIMNKGRLLK--AGRQVREPGQDLVVLPLSITTD 524
             + V++ L  +   +    K  Y   L  + G      +   +          PLSI+ D
Sbjct: 454  VVTVHYSLNSEAYEDDSNVKFFYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPLSISAD 513

Query: 525  FIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMTLK 584
              P+  L  Y   +  SG  E+VADSV   V D C    V     +E  Q +PG   +L 
Sbjct: 514  LAPAAVLFVY--TLHPSG--EIVADSVRFQV-DKCFKHKVNIKFSNE--QGLPGSNASLY 566

Query: 585  IEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKA------------DIG----CT 628
            ++        L AVD  V +L  + +L+   ++++V               D G    C 
Sbjct: 567  LQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLDDGKEDPCI 626

Query: 629  PGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMDKVGKYPK 688
            P     Y G++      +         +   L+       R+  V + E+R+      PK
Sbjct: 627  PQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLP----LPK 682

Query: 689  ELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARASHLGLAR 748
             L                                 +L+  NY       H+  S +    
Sbjct: 683  PL---------------------------------YLETENY----GPMHSVPSRIACRG 705

Query: 749  SNLDEDIIAEENIVS--RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILA 806
             N D     E+ I+   R+ FPE+W+W   DL     +G +   ++  + D+IT WE   
Sbjct: 706  ENAD---YVEQAIIQTVRTNFPETWMW---DLVSVDSSGSAN--LSFLIPDTITQWEASG 757

Query: 807  VSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQN-QELKVRVE 865
              ++   G  ++    + V Q FFI++  P+SVV+NEQ ++    ++Y     E+ V+VE
Sbjct: 758  FCVNGDVGFGISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVE 817

Query: 866  LLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFI---- 921
               N    ++ T K    + +    + +    + I+P K G   + V A           
Sbjct: 818  ESQNYE-ANINTWKINGSEVIQAGGRKTNI--WTIIPKKLGKVNITVVAESKQSSACPNE 874

Query: 922  ---------SDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVP 972
                      D V KS  V PEGI   +T +        +  EG +       DL + V 
Sbjct: 875  GMEQQKLNWKDTVVKSFLVEPEGIEKERTQSF------LICTEGAKASKQGVLDLPNDVV 928

Query: 973  DTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETE 1032
            +  +     + G  +    ++ V       ++  P G GEQN   +      + YL  TE
Sbjct: 929  EGSARGFFTVVGDILGLAMQNLV-------VLQMPYGGGEQNAALLASDTYVLDYLKSTE 981

Query: 1033 QWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAFAAF--VKRAPSTWLTAYVVKVFSLAV 1090
            Q  +   E +  A  L+  GY +QL+F+    +++ F    +  S WL+A   K      
Sbjct: 982  QLTE---EVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMK 1038

Query: 1091 NLIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLIS 1150
              + ID  V    + WL   +QK  G F+ D  + +    GG    +E+D++LTA+V+  
Sbjct: 1039 KFVFIDENVQKQTLIWL-SSQQKTSGCFKNDGQLFNHAWEGG----DEEDISLTAYVVGM 1093

Query: 1151 LQEAKDICEEQVNSLPGSITKAGDFLEANY-MNLQRSYTVAIAGYALAQMGRLKG----- 1204
              EA       +NS   ++  A   LEA     +   Y  AI  YA A  G+ K      
Sbjct: 1094 FFEA------GLNSTFPALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLL 1147

Query: 1205 PLLNKFLTTAKDKNRWED-------------PGKQLYNVEATSYALLALLQLK--DFDFV 1249
              L++  T   +   WE              P       E + Y LLA++  K  D  + 
Sbjct: 1148 QTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYA 1207

Query: 1250 PPVVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSR-SSKIT 1308
              +V+WL +Q    GG+ S Q   +    +A   ++    +  N   ++   S  SS+I 
Sbjct: 1208 SKIVQWLAQQMNSHGGFSSNQVINVGLILIAICGEEGLFSKNQN---TVTFSSEGSSEIQ 1264

Query: 1309 HRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIK 1368
               H     + RSE T+    +TV  EG+G   +     Y+     + +     L++   
Sbjct: 1265 FNGH-NRLLVQRSEVTQAPGQYTVDVEGRGCTFIQATLKYNVLLPKKASGFSLSLEIV-- 1321

Query: 1369 PAPETEKRPQDAKNTMILEICTRYRGDQD-ATMSILDISMMTGFAPDTDDLKQLANGVDR 1427
                       +     L +  +Y G ++ ++M ++D+ M++GF P    ++++ N    
Sbjct: 1322 --------KNYSLTVFDLTVNLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNN---- 1369

Query: 1428 YISKYELDKAFSDRNTLIIYLDKVSHSEDDCLA 1460
                      F  +++ I Y DK+    + CLA
Sbjct: 1370 ------RSLIFHHKDSYIEYKDKI----NTCLA 1392


>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
           blood group) [Homo sapiens]
          Length = 270

 Score =  127 bits (318), Expect = 1e-28
 Identities = 76/222 (34%), Positives = 126/222 (56%), Gaps = 11/222 (4%)

Query: 121 VLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSL 180
           +L S + G+LF+QTD+ IY PG  V YR+F ++ K+ P   T+ V +EN  G+ V++  +
Sbjct: 52  LLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTITVMVENSHGLRVRKKEV 111

Query: 181 SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTE 240
              +   +    + IP++   G WKI A + +  +   ST+FEVK+YVLP+FEV + P +
Sbjct: 112 YMPS--SIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGK 169

Query: 241 KFYYIYNEKG----LEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLK-RIPIED 295
              YI    G    +++ I AR++YGK V+G A+V FG+ D + + +    L+ +  + +
Sbjct: 170 P--YILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVN 227

Query: 296 GSGEVVLSRKVLLDGVQ--NPRAEDLVGKSLYVSATVILHSG 335
           G   + LS+    D ++  N    DL G  LYV+A +I + G
Sbjct: 228 GQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPG 269


>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
          Length = 750

 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 125/548 (22%), Positives = 207/548 (37%), Gaps = 101/548 (18%)

Query: 518  PLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVP 577
            PLSI+ D  P+  L  Y   +  SG  E+VADSV   V D C    V     +E  Q +P
Sbjct: 147  PLSISADLAPAAVLFVY--TLHPSG--EIVADSVRFQV-DKCFKHKVNIKFSNE--QGLP 199

Query: 578  GQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKA------------DI 625
            G   +L ++        L AVD  V +L  + +L+   ++++V               D 
Sbjct: 200  GSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYGYFYHGLNLDD 259

Query: 626  G----CTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQCPQPAARRRRSVQLTEKRMD 681
            G    C P     Y G++      +         +   L+       R+  V + E+R+ 
Sbjct: 260  GKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLP 319

Query: 682  KVGKYPKELRKCCEDGMRENPMRFSCQRRTRFISLGEACKKVFLDCCNYITELRRQHARA 741
                 PK L                                 +L+  NY   +    +R 
Sbjct: 320  ----LPKPL---------------------------------YLETENY-GPMHSVPSRI 341

Query: 742  SHLGLARSNLDEDIIAEENIVS--RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSI 799
            +  G+   N D     E+ I+   R+ FPE+W+W   DL     +G +   ++  + D+I
Sbjct: 342  ASSGIRGENAD---YVEQAIIQTVRTNFPETWMW---DLVSVDSSGSAN--LSFLIPDTI 393

Query: 800  TTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQN-Q 858
            T WE     ++   G  ++    + V Q FFI++  P+SVV+NEQ ++    ++Y     
Sbjct: 394  TQWEASGFCVNGDVGFGISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCV 453

Query: 859  ELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYH 918
            E+ V+VE   N    ++ T K    + +    + +    + I+P K G   + V A    
Sbjct: 454  EISVQVEESQNYE-ANINTWKINGSEVIQAGGRKTNI--WTIIPKKLGKVNITVVAESKQ 510

Query: 919  HFI-------------SDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPA 965
                             D V KS  V PEGI   +T +        +  EG +       
Sbjct: 511  SSACPNEGMEQQKLNWKDTVVKSFLVEPEGIEKERTQSF------LICTEGAKASKQGVL 564

Query: 966  DLSDQVPDTESETRILLQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAV 1025
            DL + V +  +     + G  +    ++ V       ++  P G GEQN   +      +
Sbjct: 565  DLPNDVVEGSARGFFTVVGDILGLAMQNLV-------VLQMPYGGGEQNAALLASDTYVL 617

Query: 1026 HYLDETEQ 1033
             YL  TEQ
Sbjct: 618  DYLKSTEQ 625


>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
           sapiens]
          Length = 278

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 45/152 (29%), Positives = 79/152 (51%), Gaps = 12/152 (7%)

Query: 721 KKVFLDCCNYITELRRQHARASHLGLARSNLDEDIIAEENIVS--RSEFPESWLWNVEDL 778
           K ++L+  NY   +R   +R +  G+   N D     E+ I+   R+ FPE+W+W   DL
Sbjct: 27  KPLYLETENY-GPMRSVPSRIASSGIRGENAD---YVEQAIIQTVRTNFPETWMW---DL 79

Query: 779 KEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFIDLRLPYS 838
                +G +   ++  + D+IT WE     ++   G  ++    + V Q FFI++  P+S
Sbjct: 80  VSVDSSGSAN--LSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFFIEIASPFS 137

Query: 839 VVRNEQVEIRAVLYNYRQN-QELKVRVELLHN 869
           VV+NEQ ++   +++YR    E+ V+VE   N
Sbjct: 138 VVQNEQFDLIVNVFSYRNTCVEISVQVEESQN 169


>gi|239755748 PREDICTED: ovostatin [Homo sapiens]
          Length = 257

 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 48/202 (23%), Positives = 80/202 (39%), Gaps = 19/202 (9%)

Query: 1294 LDVSLQLPSRSSKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAK 1353
            L VS      SS+I          + RSE T+    +TV  EG G   +     Y+    
Sbjct: 66   LSVSASRSEGSSEIFQVNGHNRLLVQRSEVTQAPGQYTVDVEGHGCTFIQATLKYNVLLP 125

Query: 1354 DQLTCNKFDLKVTIKPAPETEKRPQDAKNTMILEICTRYRGDQD-ATMSILDISMMTGFA 1412
             + +     L++              +     L +  +Y G ++ ++M ++D+ M++GF 
Sbjct: 126  KKASGFSLSLEIV----------KNYSSTAFDLTVTLKYTGIRNKSSMVVIDVKMLSGFT 175

Query: 1413 PDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELI 1472
            P    +++L N       K ++ K     + ++ YL+       D   F V Q   V  I
Sbjct: 176  PTMSSIEELEN-------KGQVMKTEVKNDHVLFYLEN-GFGRADSFPFSVEQSNLVFNI 227

Query: 1473 QPGAVKVYAYYNLEESCTRFYH 1494
            QP    VY YY  EE    FY+
Sbjct: 228  QPAPAMVYDYYEKEEYALAFYN 249


>gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]
          Length = 95

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 8/95 (8%)

Query: 1400 MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCL 1459
            M ++D+ M++GF P    +++L N       K ++ K     + ++ YL+       D  
Sbjct: 1    MVVIDVKMLSGFTPTMSSIEELEN-------KGQVMKTEVKNDHVLFYLEN-GFGRADSF 52

Query: 1460 AFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYH 1494
             F V Q   V  IQP    VY YY  EE    FY+
Sbjct: 53   PFSVEQSNLVFNIQPAPAMVYDYYEKEEYALAFYN 87


>gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sapiens]
          Length = 95

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 8/95 (8%)

Query: 1400 MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFSDRNTLIIYLDKVSHSEDDCL 1459
            M ++D+ M++GF P    +++L N       K ++ K     + ++ YL+       D  
Sbjct: 1    MVVIDVKMLSGFTPTMSSIEELEN-------KGQVMKTEVKNDHVLFYLEN-GFGRADSF 52

Query: 1460 AFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFYH 1494
             F V Q   V  IQP    VY YY  EE    FY+
Sbjct: 53   PFSVEQSNLVFNIQPAPAMVYDYYEKEEYALAFYN 87


>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
          Length = 1700

 Score = 35.8 bits (81), Expect = 0.36
 Identities = 42/153 (27%), Positives = 59/153 (38%), Gaps = 20/153 (13%)

Query: 337 DMVQAERSGIPIVT-SPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGED 395
           D VQ + S +   T  P  + FT TPK      P   ++    P G P   +P + +G+ 
Sbjct: 649 DQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQA 708

Query: 396 TVQSLTQGDGV---AKLSINTHPSQ--KPLSITVRTKKQE-------LSEAEQATRTMQA 443
               LTQ        +L+I T P+   KP   T  T  Q        + E    TR   A
Sbjct: 709 QHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTA 768

Query: 444 LPYSTVGNSNNY--LHLSVLR-----TELRPGE 469
           L  +T    +    LH S+       TEL P +
Sbjct: 769 LEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQ 801


>gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo
           sapiens]
          Length = 261

 Score = 35.4 bits (80), Expect = 0.46
 Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 7/99 (7%)

Query: 518 PLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVP 577
           PLSI+ D  P+  L  Y   +  SG  E+VADSV   V D C    V     +E  Q +P
Sbjct: 147 PLSISADLAPAAVLFVY--TLHPSG--EIVADSVRFQV-DKCFKHKVNIKFSNE--QGLP 199

Query: 578 GQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKI 616
           G   +L ++        L AVD+ V +L  + +L+   +
Sbjct: 200 GSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAESV 238


>gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
          Length = 7081

 Score = 34.3 bits (77), Expect = 1.0
 Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 15/146 (10%)

Query: 394 EDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQELSEAEQATRTMQALPYSTVGNSN 453
           E    S+TQ  G+     +   S+KP  + +   K  L EA   ++ MQ L  S    SN
Sbjct: 653 ESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEA--ISKPMQKLVSSPEMESN 710

Query: 454 NYL------------HLSVLRTELRPGETLNVNFLLRMDRAHEAKIRYYTYL-IMNKGRL 500
           N +            HL +   E  P  T         +   + K      L + N G L
Sbjct: 711 NRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLL 770

Query: 501 LKAGRQVREPGQDLVVLPLSITTDFI 526
           +  G ++ +  ++L  + + + T+ +
Sbjct: 771 ISPGSKMHKSSEELEAIKIQVNTESV 796


>gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo
           sapiens]
          Length = 6929

 Score = 34.3 bits (77), Expect = 1.0
 Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 15/146 (10%)

Query: 394 EDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQELSEAEQATRTMQALPYSTVGNSN 453
           E    S+TQ  G+     +   S+KP  + +   K  L EA   ++ MQ L  S    SN
Sbjct: 582 ESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEA--ISKPMQKLVSSPEMESN 639

Query: 454 NYL------------HLSVLRTELRPGETLNVNFLLRMDRAHEAKIRYYTYL-IMNKGRL 500
           N +            HL +   E  P  T         +   + K      L + N G L
Sbjct: 640 NRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLL 699

Query: 501 LKAGRQVREPGQDLVVLPLSITTDFI 526
           +  G ++ +  ++L  + + + T+ +
Sbjct: 700 ISLGSKMHKSSEELEAIKIQVNTESV 725


>gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo
           sapiens]
          Length = 6929

 Score = 34.3 bits (77), Expect = 1.0
 Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 15/146 (10%)

Query: 394 EDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQELSEAEQATRTMQALPYSTVGNSN 453
           E    S+TQ  G+     +   S+KP  + +   K  L EA   ++ MQ L  S    SN
Sbjct: 582 ESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEA--ISKPMQKLVSSPEMESN 639

Query: 454 NYL------------HLSVLRTELRPGETLNVNFLLRMDRAHEAKIRYYTYL-IMNKGRL 500
           N +            HL +   E  P  T         +   + K      L + N G L
Sbjct: 640 NRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLL 699

Query: 501 LKAGRQVREPGQDLVVLPLSITTDFI 526
           +  G ++ +  ++L  + + + T+ +
Sbjct: 700 ISLGSKMHKSSEELEAIKIQVNTESV 725


>gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo
           sapiens]
          Length = 6929

 Score = 34.3 bits (77), Expect = 1.0
 Identities = 32/146 (21%), Positives = 56/146 (38%), Gaps = 15/146 (10%)

Query: 394 EDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQELSEAEQATRTMQALPYSTVGNSN 453
           E    S+TQ  G+     +   S+KP  + +   K  L EA   ++ MQ L  S    SN
Sbjct: 582 ESLKDSITQAKGIGITEFHVLNSKKPFDLHIPKHKTSLEEA--ISKPMQKLVSSPEMESN 639

Query: 454 NYL------------HLSVLRTELRPGETLNVNFLLRMDRAHEAKIRYYTYL-IMNKGRL 500
           N +            HL +   E  P  T         +   + K      L + N G L
Sbjct: 640 NRMKIQEDLQSSENSHLQLSNGEELPTSTPKTQRCFPRENTQKQKDFLELVLELSNVGLL 699

Query: 501 LKAGRQVREPGQDLVVLPLSITTDFI 526
           +  G ++ +  ++L  + + + T+ +
Sbjct: 700 ISPGSKMHKSSEELEAIKIQVNTESV 725


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,411,960
Number of Sequences: 37866
Number of extensions: 2801009
Number of successful extensions: 6902
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 6632
Number of HSP's gapped (non-prelim): 104
length of query: 1663
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1547
effective length of database: 13,855,062
effective search space: 21433780914
effective search space used: 21433780914
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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