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Search of human proteins with 219842343
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|219842343 glutamate receptor, metabotropic 5 isoform a
precursor [Homo sapiens]
(1212 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur... 2446 0.0
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso... 2364 0.0
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr... 1396 0.0
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre... 1283 0.0
gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo s... 672 0.0
gi|66529100 glutamate receptor, metabotropic 2 isoform a precurs... 665 0.0
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens] 655 0.0
gi|187960069 glutamate receptor, metabotropic 8 isoform b precur... 654 0.0
gi|187960067 glutamate receptor, metabotropic 8 isoform a precur... 654 0.0
gi|32528268 glutamate receptor, metabotropic 7 isoform b precurs... 644 0.0
gi|4504147 glutamate receptor, metabotropic 7 isoform a precurso... 644 0.0
gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo ... 608 e-174
gi|37577159 calcium-sensing receptor [Homo sapiens] 387 e-107
gi|112807234 G protein-coupled receptor, family C, group 6, memb... 272 1e-72
gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens] 259 1e-68
gi|112789566 taste receptor, type 1, member 2 [Homo sapiens] 226 1e-58
gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo ... 198 3e-50
gi|29294619 sweet taste receptor T1r isoform c [Homo sapiens] 144 7e-34
gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens] 128 4e-29
gi|91206396 taste receptor, type 1, member 3 [Homo sapiens] 126 1e-28
gi|40255245 G protein-coupled receptor 51 [Homo sapiens] 65 3e-10
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform... 56 2e-07
gi|93204867 G protein-coupled receptor 158 [Homo sapiens] 55 4e-07
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ... 54 1e-06
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ... 54 1e-06
gi|29294621 sweet taste receptor T1r isoform d [Homo sapiens] 54 1e-06
gi|93352554 GPR158-like 1 [Homo sapiens] 52 4e-06
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 48 5e-05
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens] 46 2e-04
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 46 2e-04
>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
[Homo sapiens]
Length = 1212
Score = 2446 bits (6340), Expect = 0.0
Identities = 1212/1212 (100%), Positives = 1212/1212 (100%)
Query: 1 MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAV 60
MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAV
Sbjct: 1 MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAV 60
Query: 61 REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS 120
REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS
Sbjct: 61 REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS 120
Query: 121 EEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS 180
EEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS
Sbjct: 121 EEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS 180
Query: 181 DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGI 240
DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGI
Sbjct: 181 DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGI 240
Query: 241 CIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFL 300
CIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFL
Sbjct: 241 CIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFL 300
Query: 301 LLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQ 360
LLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQ
Sbjct: 301 LLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQ 360
Query: 361 HRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP 420
HRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP
Sbjct: 361 HRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP 420
Query: 421 GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD 480
GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD
Sbjct: 421 GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD 480
Query: 481 YINVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKEN 540
YINVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKEN
Sbjct: 481 YINVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKEN 540
Query: 541 EYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVV 600
EYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVV
Sbjct: 541 EYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVV 600
Query: 601 FIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS 660
FIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS
Sbjct: 601 FIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS 660
Query: 661 ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIM 720
ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIM
Sbjct: 661 ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIM 720
Query: 721 HDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYT 780
HDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYT
Sbjct: 721 HDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYT 780
Query: 781 TCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS 840
TCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS
Sbjct: 781 TCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS 840
Query: 841 TVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMG 900
TVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMG
Sbjct: 841 TVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMG 900
Query: 901 NGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSIHINKKENPNQTAVIKPFPKSTESRG 960
NGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSIHINKKENPNQTAVIKPFPKSTESRG
Sbjct: 901 NGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSIHINKKENPNQTAVIKPFPKSTESRG 960
Query: 961 LGAGAGAGGSAGGVGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPS 1020
LGAGAGAGGSAGGVGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPS
Sbjct: 961 LGAGAGAGGSAGGVGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPS 1020
Query: 1021 PISTLSHRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISELNSMML 1080
PISTLSHRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISELNSMML
Sbjct: 1021 PISTLSHRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISELNSMML 1080
Query: 1081 STAAPSPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAA 1140
STAAPSPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAA
Sbjct: 1081 STAAPSPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAA 1140
Query: 1141 RESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTL 1200
RESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTL
Sbjct: 1141 RESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTL 1200
Query: 1201 IIRDYTQSSSSL 1212
IIRDYTQSSSSL
Sbjct: 1201 IIRDYTQSSSSL 1212
>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
[Homo sapiens]
Length = 1180
Score = 2364 bits (6126), Expect = 0.0
Identities = 1180/1212 (97%), Positives = 1180/1212 (97%), Gaps = 32/1212 (2%)
Query: 1 MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAV 60
MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAV
Sbjct: 1 MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAV 60
Query: 61 REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS 120
REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS
Sbjct: 61 REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS 120
Query: 121 EEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS 180
EEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS
Sbjct: 121 EEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLS 180
Query: 181 DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGI 240
DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGI
Sbjct: 181 DKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGI 240
Query: 241 CIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFL 300
CIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFL
Sbjct: 241 CIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFL 300
Query: 301 LLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQ 360
LLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQ
Sbjct: 301 LLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQ 360
Query: 361 HRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP 420
HRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP
Sbjct: 361 HRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP 420
Query: 421 GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD 480
GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD
Sbjct: 421 GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD 480
Query: 481 YINVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKEN 540
YINVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKEN
Sbjct: 481 YINVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKEN 540
Query: 541 EYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVV 600
EYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVV
Sbjct: 541 EYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVV 600
Query: 601 FIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS 660
FIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS
Sbjct: 601 FIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYS 660
Query: 661 ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIM 720
ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIM
Sbjct: 661 ALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIM 720
Query: 721 HDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYT 780
HDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYT
Sbjct: 721 HDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYT 780
Query: 781 TCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS 840
TCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS
Sbjct: 781 TCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS 840
Query: 841 TVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMG 900
TVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETL
Sbjct: 841 TVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETL------------------------ 876
Query: 901 NGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSIHINKKENPNQTAVIKPFPKSTESRG 960
SSNGKSVTWAQNEKSSRGQHLWQRLSIHINKKENPNQTAVIKPFPKSTESRG
Sbjct: 877 --------SSNGKSVTWAQNEKSSRGQHLWQRLSIHINKKENPNQTAVIKPFPKSTESRG 928
Query: 961 LGAGAGAGGSAGGVGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPS 1020
LGAGAGAGGSAGGVGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPS
Sbjct: 929 LGAGAGAGGSAGGVGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPS 988
Query: 1021 PISTLSHRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISELNSMML 1080
PISTLSHRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISELNSMML
Sbjct: 989 PISTLSHRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISELNSMML 1048
Query: 1081 STAAPSPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAA 1140
STAAPSPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAA
Sbjct: 1049 STAAPSPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAA 1108
Query: 1141 RESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTL 1200
RESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTL
Sbjct: 1109 RESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTL 1168
Query: 1201 IIRDYTQSSSSL 1212
IIRDYTQSSSSL
Sbjct: 1169 IIRDYTQSSSSL 1180
>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
precursor [Homo sapiens]
Length = 1194
Score = 1396 bits (3614), Expect = 0.0
Identities = 738/1230 (60%), Positives = 891/1230 (72%), Gaps = 102/1230 (8%)
Query: 20 AQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERI 79
A +S +R VA M GD+IIGALFSVHHQP +KV ERKCG +REQYGIQRVEAM HTL++I
Sbjct: 30 AGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKI 89
Query: 80 NSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLIS-SEEEEGLVRCV-DGSS-SS 136
N+DP LLPNITLG EIRDSCWHS+VALEQSIEFIRDSLIS +E++G+ RC+ DG S
Sbjct: 90 NADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGINRCLPDGQSLPP 149
Query: 137 FRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDA 196
R+KKPI GVIGPGSSSVAIQVQNLLQLF+IPQIAYSATS+DLSDKTL+KYF+RVVPSD
Sbjct: 150 GRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDT 209
Query: 197 QQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQS 256
QARAM+DIVKRYNWTYVSAVHTEGNYGESGM+AFK+++A+EG+CIAHS KIYSNAGE+S
Sbjct: 210 LQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKS 269
Query: 257 FDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDG 316
FD+LL+KL LPKARVV CFCEGMTVRGLL AMRRLG+ GEF L+GSDGWADR +V +G
Sbjct: 270 FDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEG 329
Query: 317 YQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSK 376
Y+ EA GGITIKLQSP+V+ FDDY+LKLR +TN RNPWF EFWQHRFQCRL G EN
Sbjct: 330 YEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPN 389
Query: 377 YNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRK 436
+ + C + +L+ ++VQDSKMGFVINAIY+MA+GL NM +LCPG+ GLCDAMKPIDG K
Sbjct: 390 FKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGSK 449
Query: 437 LLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDD 496
LL+ L+K++F GVSG+ + FDE GD+PGRY+IMN + + +DY++VG+W G L +DD
Sbjct: 450 LLDFLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDD 509
Query: 497 DEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGS 556
++ KS ++RSVCSEPC KGQIKVIRKGEVSCCW CT CKENEYV DE+TCKAC LG
Sbjct: 510 YKIQMNKSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQDEFTCKACDLGW 569
Query: 557 WPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRE 616
WP DLTGC+ IPV+YL W + E I A+ F+CLG+L TLFVT++F++YRDTPVVKSSSRE
Sbjct: 570 WPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRE 629
Query: 617 LCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGS 676
LCYIILAGI LGY+C F LIAKP CYLQR+ +GLS AM YSALVTKTNRIARILAGS
Sbjct: 630 LCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGS 689
Query: 677 KKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTT 736
KKKICT+KPRFMSA AQ++IA ILI +QL ++V L IMEPP + YPSI+EVYLICNT+
Sbjct: 690 KKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTS 749
Query: 737 NLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSN 796
NLGVV PLGYNGLLI+SCT+YAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSN
Sbjct: 750 NLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSN 809
Query: 797 YKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAA 856
YKIIT CF+VSLS TVALGCMF PK+YII+AKPERNVRSAFTTS VVRMHVGDGK
Sbjct: 810 YKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGK---LP 866
Query: 857 SRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMGNGGRATMSSSNGKSVT 916
RS++ +N+++R+ K GN ++SNGKSV+
Sbjct: 867 CRSNTFLNIFRRK--------------------------KAGAGN------ANSNGKSVS 894
Query: 917 WAQ--NEKSSRGQHLWQRLSIHINKKENP-NQTAVIKPFPKSTESRGLGAGAGAGGSAGG 973
W++ + +GQH+W RLS+H+ E NQTAVIKP KS + G+G S
Sbjct: 895 WSEPGGGQVPKGQHMWHRLSVHVKTNETACNQTAVIKPLTKSYQ--------GSGKSL-- 944
Query: 974 VGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPSPISTLSHRAGSAS 1033
D K LY+V E E+ P P SP + R SA+
Sbjct: 945 -----------------TFSDTSTKTLYNVEEEEDAQPIRFSPPG-SPSMVVHRRVPSAA 986
Query: 1034 RTD--------DDVPSLHSEPV------------ARSSSSQGSLMEQISSVVTRFTANIS 1073
T ++ P +EP + Q SLM+Q+ VV+ F+ I
Sbjct: 987 TTPPLPSHLTAEETPLFLAEPALPKGLPPPLQQQQQPPPQQKSLMDQLQGVVSNFSTAIP 1046
Query: 1074 ELNSMMLSTAAPSPGVGAPLCSSYLIPKEIQ-LPTTMTTFAE--IQPLPAIEVTGGAQPA 1130
+ ++++ P G+ + L P+ +Q LP ++TF E + P PA + +
Sbjct: 1047 DFHAVLAGPGGPGNGLRS-LYPPPPPPQHLQMLPLQLSTFGEELVSP-PADDDDDSERFK 1104
Query: 1131 AGAQAAGDAARESPAAGPE--------AAAAKPDLEELVALTPPSPFRDSVDSGSTTPNS 1182
+ + RE E AA+K ++ ALTPPSPFRDSV SGS+ P+S
Sbjct: 1105 LLQEYVYEHEREGNTEEDELEEEEEDLQAASKLTPDDSPALTPPSPFRDSVASGSSVPSS 1164
Query: 1183 PVSESALCIPSSPKYDTLIIRDYTQSSSSL 1212
PVSES LC P + Y ++I+RDY QSSS+L
Sbjct: 1165 PVSESVLCTPPNVSYASVILRDYKQSSSTL 1194
>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
precursor [Homo sapiens]
Length = 906
Score = 1283 bits (3320), Expect = 0.0
Identities = 625/853 (73%), Positives = 728/853 (85%), Gaps = 6/853 (0%)
Query: 20 AQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERI 79
A +S +R VA M GD+IIGALFSVHHQP +KV ERKCG +REQYGIQRVEAM HTL++I
Sbjct: 30 AGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKI 89
Query: 80 NSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLIS-SEEEEGLVRCV-DGSS-SS 136
N+DP LLPNITLG EIRDSCWHS+VALEQSIEFIRDSLIS +E++G+ RC+ DG S
Sbjct: 90 NADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGINRCLPDGQSLPP 149
Query: 137 FRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDA 196
R+KKPI GVIGPGSSSVAIQVQNLLQLF+IPQIAYSATS+DLSDKTL+KYF+RVVPSD
Sbjct: 150 GRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDT 209
Query: 197 QQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQS 256
QARAM+DIVKRYNWTYVSAVHTEGNYGESGM+AFK+++A+EG+CIAHS KIYSNAGE+S
Sbjct: 210 LQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKS 269
Query: 257 FDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDG 316
FD+LL+KL LPKARVV CFCEGMTVRGLL AMRRLG+ GEF L+GSDGWADR +V +G
Sbjct: 270 FDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEG 329
Query: 317 YQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSK 376
Y+ EA GGITIKLQSP+V+ FDDY+LKLR +TN RNPWF EFWQHRFQCRL G EN
Sbjct: 330 YEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPN 389
Query: 377 YNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRK 436
+ + C + +L+ ++VQDSKMGFVINAIY+MA+GL NM +LCPG+ GLCDAMKPIDG K
Sbjct: 390 FKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPIDGSK 449
Query: 437 LLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDD 496
LL+ L+K++F GVSG+ + FDE GD+PGRY+IMN + + +DY++VG+W G L +DD
Sbjct: 450 LLDFLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDD 509
Query: 497 DEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGS 556
++ KS ++RSVCSEPC KGQIKVIRKGEVSCCW CT CKENEYV DE+TCKAC LG
Sbjct: 510 YKIQMNKSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQDEFTCKACDLGW 569
Query: 557 WPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRE 616
WP DLTGC+ IPV+YL W + E I A+ F+CLG+L TLFVT++F++YRDTPVVKSSSRE
Sbjct: 570 WPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRE 629
Query: 617 LCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGS 676
LCYIILAGI LGY+C F LIAKP CYLQR+ +GLS AM YSALVTKTNRIARILAGS
Sbjct: 630 LCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGS 689
Query: 677 KKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTT 736
KKKICT+KPRFMSA AQ++IA ILI +QL ++V L IMEPP + YPSI+EVYLICNT+
Sbjct: 690 KKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTS 749
Query: 737 NLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSN 796
NLGVV PLGYNGLLI+SCT+YAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSN
Sbjct: 750 NLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSN 809
Query: 797 YKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAA 856
YKIIT CF+VSLS TVALGCMF PK+YII+AKPERNVRSAFTTS VVRMHVGDGK
Sbjct: 810 YKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGK---LP 866
Query: 857 SRSSSLVNLWKRR 869
RS++ +N+++R+
Sbjct: 867 CRSNTFLNIFRRK 879
>gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo
sapiens]
Length = 879
Score = 672 bits (1735), Expect = 0.0
Identities = 365/817 (44%), Positives = 512/817 (62%), Gaps = 35/817 (4%)
Query: 33 GDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLG 92
GD+++G LF ++ + T + +CG + E GIQR+EAML ++ IN D LLP + LG
Sbjct: 37 GDLVLGGLFPINEKGTGTE----ECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLG 92
Query: 93 CEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKP--IVGVIGPG 150
I D+C ALEQS+EF+R SL +E E + C DGS + + P I GVIG
Sbjct: 93 VHILDTCSRDTYALEQSLEFVRASLTKVDEAEYM--CPDGSYA-IQENIPLLIAGVIGGS 149
Query: 151 SSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYN 210
SSV+IQV NLL+LF IPQI+Y++TS LSDK+ + YF R VP D QA+AM +I++ +N
Sbjct: 150 YSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFN 209
Query: 211 WTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTSHLPK 270
WTYVS V +EG+YGE+G+EAF+ + ICIA + K+ + +S+D ++++L P
Sbjct: 210 WTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQK-PN 268
Query: 271 ARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQ 330
ARVV F R L+ A R + F + SDGW + + G + A G IT++L
Sbjct: 269 ARVVVLFMRSDDSRELIAAASRANAS--FTWVASDGWGAQESIIKGSEHVAYGAITLELA 326
Query: 331 SPDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTL-KT 389
S V+ FD Y+ L P NHRNPWF++FW+ +FQC L Q + + C+ L + +
Sbjct: 327 SQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSL----QNKRNHRRVCDKHLAIDSS 382
Query: 390 HHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLES-LMKTNFTG 448
++ Q+SK+ FV+NA+Y+MA+ LH MQ +LCP LCDAMK +DG+KL + L+K NFT
Sbjct: 383 NYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGKKLYKDYLLKINFTA 442
Query: 449 V-----SGDTIL-FDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVWSK 502
D+I+ FD GD GRY + NF+ +G Y Y+ VG W L +D + +
Sbjct: 443 PFNPNKDADSIVKFDTFGDGMGRYNVFNFQNVGGKY-SYLKVGHWAE-TLSLDVNSIHWS 500
Query: 503 KSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDL 562
++++ S CS+PC ++K ++ G+V CCW C PC+ EY+ DE+TC C G WPT DL
Sbjct: 501 RNSVPTSQCSDPCAPNEMKNMQPGDV-CCWICIPCEPYEYLADEFTCMDCGSGQWPTADL 559
Query: 563 TGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIIL 622
TGC +P Y+RW D I V ACLG + T V VFI + +TP+VK+S RELCYI+L
Sbjct: 560 TGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRELCYILL 619
Query: 623 AGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICT 682
G+ L Y TF IAKP + C L+R+G+G S A+ YSAL+TKTN IARI G K
Sbjct: 620 FGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNG--A 677
Query: 683 KKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDI-MHDYPSIRE-VYLICNTTNLGV 740
++P+F+S +Q+ I LI +Q+ ++ I+E P + RE V L CN + +
Sbjct: 678 QRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNVKDSSM 737
Query: 741 VTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYF--GSNYK 798
+ L Y+ +L++ CT YAFKTR P NFNEAK+I FTMYTTCIIWLAF+PI++ S+Y+
Sbjct: 738 LISLTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYR 797
Query: 799 I--ITMCFSVSLSATVALGCMFVPKVYIILAKPERNV 833
+ TMC SVSLS V LGC+F PKV+IIL +P++NV
Sbjct: 798 VQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNV 834
>gi|66529100 glutamate receptor, metabotropic 2 isoform a precursor
[Homo sapiens]
Length = 872
Score = 665 bits (1715), Expect = 0.0
Identities = 385/877 (43%), Positives = 519/877 (59%), Gaps = 54/877 (6%)
Query: 3 LLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQ--PTVDKVHERKCGAV 60
LL +L++LLL G+ + V + GD+++G LF VH + P D CG V
Sbjct: 4 LLALLALLLLW----GAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAED------CGPV 53
Query: 61 REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS 120
E GIQR+EAML L+RIN DP LLP + LG I DSC ALEQ+++F+R SL
Sbjct: 54 NEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRG 113
Query: 121 EEEEGLVRCVDGSSSSFR-SKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDL 179
+ + C DGS ++ + I GVIG S V+IQV NLL+LF IPQI+Y++TS L
Sbjct: 114 ADGSRHI-CPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKL 172
Query: 180 SDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEG 239
SDK+ + YF R VP D QA+AM +I++ +NWTYVS V +EG+YGE+G+EAF+ +
Sbjct: 173 SDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARN 232
Query: 240 ICIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEF 299
IC+A S K+ +F+ +++ L P ARV F R LL A +RL + F
Sbjct: 233 ICVATSEKVGRAMSRAAFEGVVRALLQK-PSARVAVLFTRSEDARELLAASQRLNAS--F 289
Query: 300 LLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFW 359
+ SDGW V G + A G ITI+L S + F Y+ L P N RNPWF+EFW
Sbjct: 290 TWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFW 349
Query: 360 QHRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLC 419
+ RF+C + C + Q+SK+ FV+NA+Y+MA+ LHNM +LC
Sbjct: 350 EQRFRCSFR---------QRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALC 400
Query: 420 PGYAGLCDAMKPIDGRKLLESLM---KTNFTGVSGDT---ILFDENGDSPGRYEIMNFKE 473
P LCDAM+P++GR+L + + K + DT + FD GD GRY I +
Sbjct: 401 PNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLR 460
Query: 474 MGKDYFDYINVGSWDNGELKMDDDEV-WSKKSN--IIRSVCSEPCEKGQIKVIRKGEVSC 530
G + Y VG W G L +D + W+ S + S CSEPC + ++K ++ GEV C
Sbjct: 461 AGSGRYRYQKVGYWAEG-LTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEV-C 518
Query: 531 CWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLG 590
CW C PC+ EY DE+TC C LG WP LTGC +P +Y+RWGD + V ACLG
Sbjct: 519 CWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLG 578
Query: 591 LLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIG 650
LATLFV VF+ + TPVVK+S RELCYI+L G+ L Y TF IAKP C L+R+G
Sbjct: 579 ALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLG 638
Query: 651 IGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVA 710
+G + ++ YSAL+TKTNRIARI G+++ ++PRF+S +Q+ I LI QL I+VA
Sbjct: 639 LGTAFSVCYSALLTKTNRIARIFGGAREG--AQRPRFISPASQVAICLALISGQLLIVVA 696
Query: 711 LFIMEPPDI-MHDYPSIREVY-LICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANF 768
++E P P REV L CN + ++ L YN LLI CT YAFKTR P NF
Sbjct: 697 WLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENF 756
Query: 769 NEAKYIAFTMYTTCIIWLAFVPIYF--GSNYKI--ITMCFSVSLSATVALGCMFVPKVYI 824
NEAK+I FTMYTTCIIWLAF+PI++ S+Y++ TMC SVSLS +V LGC+F PK++I
Sbjct: 757 NEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHI 816
Query: 825 ILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSS 861
IL +P++N VV + SAA+R+SS
Sbjct: 817 ILFQPQKN---------VVSHRAPTSRFGSAAARASS 844
>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
Length = 912
Score = 655 bits (1691), Expect = 0.0
Identities = 355/819 (43%), Positives = 499/819 (60%), Gaps = 30/819 (3%)
Query: 33 GDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLG 92
GDI +G LF VH + + K CG ++++ GI R+EAML L+RIN+DP LLPNITLG
Sbjct: 47 GDITLGGLFPVHGRGSEGK----PCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLG 102
Query: 93 CEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSS 152
I D+C ALEQS+ F++ +LI + E VRC G + +VGVIG S
Sbjct: 103 ARILDTCSRDTHALEQSLTFVQ-ALIEKDGTE--VRCGSGGPPIITKPERVVGVIGASGS 159
Query: 153 SVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWT 212
SV+I V N+L+LF IPQI+Y++T+ DLSD + + +F RVVPSD QA+AMVDIV+ W
Sbjct: 160 SVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWN 219
Query: 213 YVSAVHTEGNYGESGMEAFKDMSAKEG-ICIAHSYKIYSNAGEQSFDKLLKKLTSHLPKA 271
YVS V +EG+YGESG+EAF S ++G +CIA S KI FDK++++L A
Sbjct: 220 YVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLE-TSNA 278
Query: 272 RVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQS 331
R V F +R +L A RR G F +GSD W + + A G +TI +
Sbjct: 279 RAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKR 338
Query: 332 PDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTL--KT 389
V+ FD Y+ + N RN WF EFW+ F C+L + + K C + + +
Sbjct: 339 MSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDS 398
Query: 390 HHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNFTGV 449
+ Q+ K+ FVI+A+Y+M + LH M LCPG GLC M P+DG +LL+ + NF+G+
Sbjct: 399 AYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGI 458
Query: 450 SGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSW-DNGELKMDDDEVWSKKSNIIR 508
+G+ + F+ENGD+PGRY+I + ++ D +Y +GSW D+ L+++ + R
Sbjct: 459 AGNPVTFNENGDAPGRYDIYQY-QLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPR 517
Query: 509 SVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLI 568
S+CS PC+ G+ K KG + CCW C PC +Y D YTCK C PT++ TGC I
Sbjct: 518 SICSLPCQPGERKKTVKG-MPCCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPI 576
Query: 569 PVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLG 628
P+ L WG P + + A +G+ ATLFV + F+ Y DTP+VK+S REL Y++LAGI L
Sbjct: 577 PIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLC 636
Query: 629 YLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFM 688
Y TF +IA+P C L+RI +GL ++SY+AL+TKTNRI RI K+ + PRF+
Sbjct: 637 YATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSV--SAPRFI 694
Query: 689 SACAQLVIAFILICIQLGIIVALFIMEPPDIMHDY-------PSIREVYLICNTTNLGVV 741
S +QL I F LI +QL I F+++P + D+ P L C+ ++L ++
Sbjct: 695 SPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLI 754
Query: 742 TPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSN----- 796
LGY+ LL+++CT YA KTR VP FNEAK I FTMYTTCI+WLAF+PI+FG++
Sbjct: 755 CLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADK 814
Query: 797 --YKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNV 833
+ T+ SVSLSA+V+LG +++PKVYIIL PE+NV
Sbjct: 815 LYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNV 853
>gi|187960069 glutamate receptor, metabotropic 8 isoform b precursor
[Homo sapiens]
Length = 908
Score = 654 bits (1688), Expect = 0.0
Identities = 360/823 (43%), Positives = 499/823 (60%), Gaps = 37/823 (4%)
Query: 33 GDIIIGALFSVHHQPTVDKVHER--KCGAVREQYGIQRVEAMLHTLERINSDPTLLPNIT 90
GDII+G LF VH + ER CG ++++ GI R+EAML+ +++IN DP LL NIT
Sbjct: 44 GDIILGGLFPVHAKG------ERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNIT 97
Query: 91 LGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPG 150
LG I D+C ALEQS+ F++ + E++ V+C +G F I GVIG
Sbjct: 98 LGVRILDTCSRDTYALEQSLTFVQALI---EKDASDVKCANGDPPIFTKPDKISGVIGAA 154
Query: 151 SSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYN 210
+SSV+I V N+L+LF IPQI+Y++T+ +LSD T + +F RVVP D+ QA+AMVDIV
Sbjct: 155 ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALG 214
Query: 211 WTYVSAVHTEGNYGESGMEAFKDMSAK-EGICIAHSYKIYSNAGEQSFDKLLKKLTSHLP 269
W YVS + +EGNYGESG+EAF +S + G+CIA S KI F+K++K+L P
Sbjct: 215 WNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TP 273
Query: 270 KARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAV--GGITI 327
AR V F +R +L A ++L +G FL +GSD W + + YQ+E + G +TI
Sbjct: 274 NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSK--IAPVYQQEEIAEGAVTI 331
Query: 328 KLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNK-TCNSSLT 386
+ + FD Y+ N RN WF EFW+ F C+L + NS K T +
Sbjct: 332 LPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIA 391
Query: 387 LKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNF 446
+ + Q+ K+ FVI+A+YSMAY LHNM LCPGY GLC M IDG++LL + NF
Sbjct: 392 RDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNF 451
Query: 447 TGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNG-ELKMDDDEVWSKKSN 505
G +G + F+ENGD+PGRY+I ++ K +Y +G W N LK++D + ++
Sbjct: 452 NGSAGTPVTFNENGDAPGRYDIFQYQITNKST-EYKVIGHWTNQLHLKVEDMQWAHREHT 510
Query: 506 IIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGC 565
SVCS PC+ G+ K KG V CCW C C+ Y DE +C+ C L P + TGC
Sbjct: 511 HPASVCSLPCKPGERKKTVKG-VPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGC 569
Query: 566 DLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGI 625
LIP+ L W P + V A LG++AT FV V F+ Y DTP+V++S REL Y++L GI
Sbjct: 570 QLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGI 629
Query: 626 CLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKP 685
L Y TF +IA P I C +R+ +GL SY+AL+TKTNRI RI KK + P
Sbjct: 630 FLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTA--P 687
Query: 686 RFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDY-------PSIREVYLICNTTNL 738
+F+S +QLVI F LI +QL + F+++PP I+ DY P L C+ ++L
Sbjct: 688 KFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDL 747
Query: 739 GVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGS--- 795
++ LGY+ LL+++CT YA KTR VP FNEAK I FTMYTTCIIWLAF+PI+FG+
Sbjct: 748 SLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQS 807
Query: 796 ----NYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVR 834
+ T+ S+SLSA+V+LG +++PKVYII+ PE+NV+
Sbjct: 808 AEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQ 850
>gi|187960067 glutamate receptor, metabotropic 8 isoform a precursor
[Homo sapiens]
Length = 908
Score = 654 bits (1688), Expect = 0.0
Identities = 360/823 (43%), Positives = 499/823 (60%), Gaps = 37/823 (4%)
Query: 33 GDIIIGALFSVHHQPTVDKVHER--KCGAVREQYGIQRVEAMLHTLERINSDPTLLPNIT 90
GDII+G LF VH + ER CG ++++ GI R+EAML+ +++IN DP LL NIT
Sbjct: 44 GDIILGGLFPVHAKG------ERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNIT 97
Query: 91 LGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPG 150
LG I D+C ALEQS+ F++ + E++ V+C +G F I GVIG
Sbjct: 98 LGVRILDTCSRDTYALEQSLTFVQALI---EKDASDVKCANGDPPIFTKPDKISGVIGAA 154
Query: 151 SSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYN 210
+SSV+I V N+L+LF IPQI+Y++T+ +LSD T + +F RVVP D+ QA+AMVDIV
Sbjct: 155 ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALG 214
Query: 211 WTYVSAVHTEGNYGESGMEAFKDMSAK-EGICIAHSYKIYSNAGEQSFDKLLKKLTSHLP 269
W YVS + +EGNYGESG+EAF +S + G+CIA S KI F+K++K+L P
Sbjct: 215 WNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TP 273
Query: 270 KARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAV--GGITI 327
AR V F +R +L A ++L +G FL +GSD W + + YQ+E + G +TI
Sbjct: 274 NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSK--IAPVYQQEEIAEGAVTI 331
Query: 328 KLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNK-TCNSSLT 386
+ + FD Y+ N RN WF EFW+ F C+L + NS K T +
Sbjct: 332 LPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIA 391
Query: 387 LKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNF 446
+ + Q+ K+ FVI+A+YSMAY LHNM LCPGY GLC M IDG++LL + NF
Sbjct: 392 RDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNF 451
Query: 447 TGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNG-ELKMDDDEVWSKKSN 505
G +G + F+ENGD+PGRY+I ++ K +Y +G W N LK++D + ++
Sbjct: 452 NGSAGTPVTFNENGDAPGRYDIFQYQITNKST-EYKVIGHWTNQLHLKVEDMQWAHREHT 510
Query: 506 IIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGC 565
SVCS PC+ G+ K KG V CCW C C+ Y DE +C+ C L P + TGC
Sbjct: 511 HPASVCSLPCKPGERKKTVKG-VPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGC 569
Query: 566 DLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGI 625
LIP+ L W P + V A LG++AT FV V F+ Y DTP+V++S REL Y++L GI
Sbjct: 570 QLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGI 629
Query: 626 CLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKP 685
L Y TF +IA P I C +R+ +GL SY+AL+TKTNRI RI KK + P
Sbjct: 630 FLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTA--P 687
Query: 686 RFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDY-------PSIREVYLICNTTNL 738
+F+S +QLVI F LI +QL + F+++PP I+ DY P L C+ ++L
Sbjct: 688 KFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDL 747
Query: 739 GVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGS--- 795
++ LGY+ LL+++CT YA KTR VP FNEAK I FTMYTTCIIWLAF+PI+FG+
Sbjct: 748 SLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQS 807
Query: 796 ----NYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVR 834
+ T+ S+SLSA+V+LG +++PKVYII+ PE+NV+
Sbjct: 808 AEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQ 850
>gi|32528268 glutamate receptor, metabotropic 7 isoform b precursor
[Homo sapiens]
Length = 922
Score = 644 bits (1661), Expect = 0.0
Identities = 351/850 (41%), Positives = 509/850 (59%), Gaps = 33/850 (3%)
Query: 6 ILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYG 65
+L VLL Q + GD+ +G LF VH + CG ++ + G
Sbjct: 20 VLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGV----PCGDIKRENG 75
Query: 66 IQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEG 125
I R+EAML+ L++INSDP LLPN+TLG I D+C ALEQS+ F++ +LI + +
Sbjct: 76 IHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQ-ALIQKDTSD- 133
Query: 126 LVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLF 185
VRC +G F + +VGVIG SSV+I V N+L+LF IPQI+Y++T+ +LSD +
Sbjct: 134 -VRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRY 192
Query: 186 KYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEG-ICIAH 244
+F RVVP D+ QA+AMVDIVK W YVS + +EG+YGE G+E+F +S + G +CIA
Sbjct: 193 DFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQ 252
Query: 245 SYKIYSNAGEQS--FDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLL 302
S +I +++ FD+++K+L P +R V F ++ +L A +R G FL +
Sbjct: 253 SVRIPQERKDRTIDFDRIIKQLLD-TPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWV 311
Query: 303 GSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHR 362
GSD W + + ++ A G ITI+ + V+ FD Y+ E N RN WF E+W+
Sbjct: 312 GSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEEN 371
Query: 363 FQCRL--EGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP 420
F C+L G +E++ T + +++ Q+ K+ FVI+A+Y+MA+ LH+M LC
Sbjct: 372 FNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCA 431
Query: 421 GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD 480
Y G+C M+ G+KLL+ + NF G +G ++F++NGD+PGRY+I ++
Sbjct: 432 DYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPG 491
Query: 481 YINVGSWDNGELKMD-DDEVWSKK-SNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCK 538
Y +G W + EL+++ +D W K I SVC+ PC+ GQ K +KG CCWTC PC
Sbjct: 492 YRLIGQWTD-ELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKG-TPCCWTCEPCD 549
Query: 539 ENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVT 598
+Y FDE TC+ C P ++ TGC IP+ L W P + V A LG++AT+FV
Sbjct: 550 GYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVM 609
Query: 599 VVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMS 658
FI Y DTP+V++S REL Y++L GI L Y+ TF +IAKP C +R+ +GL +S
Sbjct: 610 ATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCIS 669
Query: 659 YSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPD 718
Y+AL+TKTNRI RI KK + PR +S +QL I LI +QL + F ++PP+
Sbjct: 670 YAALLTKTNRIYRIFEQGKKSVTA--PRLISPTSQLAITSSLISVQLLGVFIWFGVDPPN 727
Query: 719 IMHDY-------PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEA 771
I+ DY P L C+ T+L ++ LGY+ LL+++CT YA KTR VP NFNEA
Sbjct: 728 IIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEA 787
Query: 772 KYIAFTMYTTCIIWLAFVPIYFGS-------NYKIITMCFSVSLSATVALGCMFVPKVYI 824
K I FTMYTTCI+WLAF+PI+FG+ + T+ S++LSA+VALG +++PKVYI
Sbjct: 788 KPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYI 847
Query: 825 ILAKPERNVR 834
I+ PE NV+
Sbjct: 848 IIFHPELNVQ 857
>gi|4504147 glutamate receptor, metabotropic 7 isoform a precursor
[Homo sapiens]
Length = 915
Score = 644 bits (1661), Expect = 0.0
Identities = 351/850 (41%), Positives = 509/850 (59%), Gaps = 33/850 (3%)
Query: 6 ILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYG 65
+L VLL Q + GD+ +G LF VH + CG ++ + G
Sbjct: 20 VLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGV----PCGDIKRENG 75
Query: 66 IQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEG 125
I R+EAML+ L++INSDP LLPN+TLG I D+C ALEQS+ F++ +LI + +
Sbjct: 76 IHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQ-ALIQKDTSD- 133
Query: 126 LVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLF 185
VRC +G F + +VGVIG SSV+I V N+L+LF IPQI+Y++T+ +LSD +
Sbjct: 134 -VRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRY 192
Query: 186 KYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEG-ICIAH 244
+F RVVP D+ QA+AMVDIVK W YVS + +EG+YGE G+E+F +S + G +CIA
Sbjct: 193 DFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQ 252
Query: 245 SYKIYSNAGEQS--FDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLL 302
S +I +++ FD+++K+L P +R V F ++ +L A +R G FL +
Sbjct: 253 SVRIPQERKDRTIDFDRIIKQLLD-TPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWV 311
Query: 303 GSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHR 362
GSD W + + ++ A G ITI+ + V+ FD Y+ E N RN WF E+W+
Sbjct: 312 GSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYWEEN 371
Query: 363 FQCRL--EGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCP 420
F C+L G +E++ T + +++ Q+ K+ FVI+A+Y+MA+ LH+M LC
Sbjct: 372 FNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCA 431
Query: 421 GYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD 480
Y G+C M+ G+KLL+ + NF G +G ++F++NGD+PGRY+I ++
Sbjct: 432 DYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPG 491
Query: 481 YINVGSWDNGELKMD-DDEVWSKK-SNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCK 538
Y +G W + EL+++ +D W K I SVC+ PC+ GQ K +KG CCWTC PC
Sbjct: 492 YRLIGQWTD-ELQLNIEDMQWGKGVREIPASVCTLPCKPGQRKKTQKG-TPCCWTCEPCD 549
Query: 539 ENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVT 598
+Y FDE TC+ C P ++ TGC IP+ L W P + V A LG++AT+FV
Sbjct: 550 GYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVM 609
Query: 599 VVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMS 658
FI Y DTP+V++S REL Y++L GI L Y+ TF +IAKP C +R+ +GL +S
Sbjct: 610 ATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCIS 669
Query: 659 YSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPD 718
Y+AL+TKTNRI RI KK + PR +S +QL I LI +QL + F ++PP+
Sbjct: 670 YAALLTKTNRIYRIFEQGKKSVTA--PRLISPTSQLAITSSLISVQLLGVFIWFGVDPPN 727
Query: 719 IMHDY-------PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEA 771
I+ DY P L C+ T+L ++ LGY+ LL+++CT YA KTR VP NFNEA
Sbjct: 728 IIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEA 787
Query: 772 KYIAFTMYTTCIIWLAFVPIYFGS-------NYKIITMCFSVSLSATVALGCMFVPKVYI 824
K I FTMYTTCI+WLAF+PI+FG+ + T+ S++LSA+VALG +++PKVYI
Sbjct: 788 KPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYI 847
Query: 825 ILAKPERNVR 834
I+ PE NV+
Sbjct: 848 IIFHPELNVQ 857
>gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo
sapiens]
Length = 877
Score = 608 bits (1569), Expect = e-174
Identities = 345/847 (40%), Positives = 496/847 (58%), Gaps = 38/847 (4%)
Query: 31 MPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNIT 90
+ G + +G LF VH + R CG ++++ G+ R+EAML+ L+R+N+DP LLP +
Sbjct: 35 LAGGLTLGGLFPVHARGAAG----RACGQLKKEQGVHRLEAMLYALDRVNADPELLPGVR 90
Query: 91 LGCEIRDSCWHSAVALEQSIEFIRDSLIS-SEEEEGLVRCVDGSSSSFRSKKP--IVGVI 147
LG + D+C ALEQ++ F++ + + +E VRC G R P +V V+
Sbjct: 91 LGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEVGVRC-PGGVPPLRPAPPERVVAVV 149
Query: 148 GPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVK 207
G +SSV+I V N+L+LF IPQI+Y++T+ +LSD T + +F RVVP D+ QA+AMVDIV+
Sbjct: 150 GASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVR 209
Query: 208 RYNWTYVSAVHTEGNYGESGMEAFKDMSAKEG-ICIAHSYKIYSNAGEQSFDKLLKKLTS 266
W YVS + +EGNYGESG+EAF +S + G +CIA S KI F K++++L
Sbjct: 210 ALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIKIPREPKPGEFSKVIRRLME 269
Query: 267 HLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGIT 326
P AR + F +R +L A R+ L G FL +GSD W + + AVG IT
Sbjct: 270 -TPNARGIIIFANEDDIRRVLEAARQANLTGHFLWVGSDSWGAKTSPILSLEDVAVGAIT 328
Query: 327 IKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRL--EGFPQENSKYNKTCNSS 384
I + + FD Y++ E N RN WF EFW+ F C+L G ++S T
Sbjct: 329 ILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCKLTSSGTQSDDSTRKCTGEER 388
Query: 385 LTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKT 444
+ + + Q+ K+ FVI+A+Y++A+ LH+M +LCPG+ GLC AM+P DGR LL+ +
Sbjct: 389 IGRDSTYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTGLCPAMEPTDGRMLLQYIRAV 448
Query: 445 NFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFD--YINVGSWDNGELKMDDDEV-WS 501
F G +G ++F+ENGD+PGRY+I ++ Y VG W L++D + + WS
Sbjct: 449 RFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQWAE-TLRLDVEALQWS 507
Query: 502 KKSNII-RSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTD 560
+ + S+CS PC G+ K + KG V CCW C C + DE+TC+AC PT
Sbjct: 508 GDPHEVPSSLCSLPCGPGERKKMVKG-VPCCWHCEACDGYRFQVDEFTCEACPGDMRPTP 566
Query: 561 DLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYI 620
+ TGC PV L W P ++ A LG++AT V F+ Y +TP+V++S REL Y+
Sbjct: 567 NHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVATTTVVATFVRYNNTPIVRASGRELSYV 626
Query: 621 ILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKI 680
+L GI L Y TF ++A+P C +R+ +GL +SYSAL+TKTNRI RI K+ +
Sbjct: 627 LLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLGTTLSYSALLTKTNRIYRIFEQGKRSV 686
Query: 681 CTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREV-------YLIC 733
P F+S +QLVI F L +Q+ ++A PP + DY R V L C
Sbjct: 687 --TPPPFISPTSQLVITFSLTSLQVVGMIAWLGARPPHSVIDYEEQRTVDPEQARGVLKC 744
Query: 734 NTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYF 793
+ ++L ++ LGY+ LL+++CT YA K R VP FNEAK I FTMYTTCIIWLAFVPI+F
Sbjct: 745 DMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKPIGFTMYTTCIIWLAFVPIFF 804
Query: 794 GS-------NYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNV----RSAFTTSTV 842
G+ + T+ S+SLSA+V+LG ++VPK Y+IL PE+NV RS TSTV
Sbjct: 805 GTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVILFHPEQNVQKRKRSLKATSTV 864
Query: 843 VRMHVGD 849
G+
Sbjct: 865 AAPPKGE 871
>gi|37577159 calcium-sensing receptor [Homo sapiens]
Length = 1078
Score = 387 bits (995), Expect = e-107
Identities = 274/919 (29%), Positives = 448/919 (48%), Gaps = 89/919 (9%)
Query: 19 SAQSSERRVVAHMPGDIIIGALFSVHHQPTVD----KVHERKCGAVREQY-GIQRVEAML 73
SA ++R A GDII+G LF +H K +R + G + ++AM+
Sbjct: 18 SAYGPDQR--AQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRYNFRGFRWLQAMI 75
Query: 74 HTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGS 133
+E INS P LLPN+TLG I D+C + ALE ++ F+ + I S + C +
Sbjct: 76 FAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKIDSLNLDEFCNCSEHI 135
Query: 134 SSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVP 193
S+ + V+G S V+ V NLL LF IPQ++Y+++S LS+K FK F+R +P
Sbjct: 136 PST-------IAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKSFLRTIP 188
Query: 194 SDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAG 253
+D QA AM DI++ + W +V + + +YG G+E F++ + + ICI S I +
Sbjct: 189 NDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSELISQYSD 248
Query: 254 EQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDV 313
E+ +++ + + A+V+ F G + L+ + R + G+ + L S+ WA +
Sbjct: 249 EEEIQHVVEVIQN--STAKVIVVFSSGPDLEPLIKEIVRRNITGK-IWLASEAWASSSLI 305
Query: 314 TDGYQREAVGG-ITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRL----- 367
VGG I L++ + F ++ K+ P + N + +EFW+ F C L
Sbjct: 306 AMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNCHLQEGAK 365
Query: 368 ----------------EGFPQENSKYNKTCNSS---LTLKTHHVQDSKMGFVIN---AIY 405
+ F ++ + C +++T ++ + + N A+Y
Sbjct: 366 GPLPVDTFLRGHEESGDRFSNSSTAFRPLCTGDENISSVETPYIDYTHLRISYNVYLAVY 425
Query: 406 SMAYGLHNMQMSLCPGYA----GLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGD 461
S+A+ L ++ L PG G C +K ++ ++L+ L NFT G+ + FDE GD
Sbjct: 426 SIAHALQDIYTCL-PGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGD 484
Query: 462 SPGRYEIMN-----------FKEMGKDYFDYINVGSWDNGELKMDDDEV-WSKKSNIIR- 508
G Y I+N FKE+G Y NV + L ++++++ WS S +
Sbjct: 485 LVGNYSIINWHLSPEDGSIVFKEVG-----YYNVYAKKGERLFINEEKILWSGFSREVPF 539
Query: 509 SVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEY--VFDEYTCKACQLGSWPTDDLTGCD 566
S CS C G K I +GE +CC+ C C + EY D C C W ++ T C
Sbjct: 540 SNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKCPDDFWSNENHTSCI 599
Query: 567 LIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGIC 626
+++L W +P IA +FA LG+ T FV VFI +R+TP+VK+++REL Y++L +
Sbjct: 600 AKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLLLFSLL 659
Query: 627 LGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPR 686
+ + I +P+ C L++ G+S + S ++ KTNR+ + + KI T R
Sbjct: 660 CCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVF---EAKIPTSFHR 716
Query: 687 -FMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIRE-VYLICNTTNLGVVTPL 744
+ Q ++ F+ +Q+ I V PP + E +++ C+ +L + L
Sbjct: 717 KWWGLNLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFITCHEGSLMALGFL 776
Query: 745 -GYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMC 803
GY LL C F+AFK+R +P NFNEAK+I F+M I+W++F+P Y + K ++
Sbjct: 777 IGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTYGKFVSAV 836
Query: 804 FSVSLSATV--ALGCMFVPKVYIILAKPERNVRSAFTTSTV-----VRMHVGDGKSSSAA 856
+++ A L C+F K+YIIL KP RN ST V +S+ +
Sbjct: 837 EVIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVRCSTAAHAFKVAARATLRRSNVSR 896
Query: 857 SRSSSLVNLWKRRGSSGET 875
RSSSL GS+G T
Sbjct: 897 KRSSSL------GGSTGST 909
>gi|112807234 G protein-coupled receptor, family C, group 6, member
A [Homo sapiens]
Length = 926
Score = 272 bits (696), Expect = 1e-72
Identities = 265/994 (26%), Positives = 424/994 (42%), Gaps = 111/994 (11%)
Query: 3 LLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVRE 62
L+++++ ++ Q+ + V A PG IIIG LF++H + + R+ ++E
Sbjct: 4 LIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRR-PQIQE 62
Query: 63 QYGIQ-----RVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSL 117
G + + AM+H++E IN+ TLLP + LG EI D+C VA+ ++ F+
Sbjct: 63 CVGFEISVFLQTLAMIHSIEMINNS-TLLPGVKLGYEIYDTCTEVTVAMAATLRFLSKFN 121
Query: 118 ISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSM 177
S E E +C D SS R K VIG G S + + V +L L +PQ+ Y +T+
Sbjct: 122 CSRETVE--FKC-DYSSYMPRVK----AVIGSGYSEITMAVSRMLNLQLMPQVGYESTAE 174
Query: 178 DLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAK 237
LSDK F F+R VPSD Q +AM ++++ W ++ + T+ +YG + F +
Sbjct: 175 ILSDKIRFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEA 234
Query: 238 EGICIAHSYK----IYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRL 293
+CIA + N E ++ LKK+ + V+ F V L +
Sbjct: 235 NNVCIAFKEVLPAFLSDNTIEVRINRTLKKIILE-AQVNVIVVFLRQFHVFDLFNKAIEM 293
Query: 294 GLAGEFLLLGSDGWADRYDVTDGYQREAVGGIT-IKLQSPDVKWFDDYY--LKLRPETNH 350
+ + + SD W+ +T + +G + + ++ F + L L P +H
Sbjct: 294 NI--NKMWIASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSH 351
Query: 351 RNPWFQEFWQHRFQCR----------LEGFPQENSKY--NKTCNSSLTLKTHHVQDSKMG 398
+ E+ H C + Q Y NK + ++ + D
Sbjct: 352 K--LLHEYAMHLSACAYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEP 409
Query: 399 FVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDE 458
+I++I + L LC A C +LL L FT ++ FD
Sbjct: 410 GLIHSIQLAVFALGYAIRDLC--QARDCQNPNAFQPWELLGVLKNVTFTD-GWNSFHFDA 466
Query: 459 NGDSPGRYEIMNFKEMGKDYFDYINVGSWD--NGELKMDDDEVWSKKSNI--IRSVCSEP 514
+GD Y+++ +KE+ + + +D N + D E ++ N+ I+S CS+
Sbjct: 467 HGDLNTGYDVVLWKEI-NGHMTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKE 525
Query: 515 CEKGQIKVIRKGEVSCCWTCTPCKENEYV--FDEYTCKACQLGS-WPTDDLTGCDLIPVQ 571
C GQ+K + + CC+ C C EN Y D C C + W T C V+
Sbjct: 526 CSPGQMKKTTRSQHICCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVE 585
Query: 572 YLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSS-SRELCYIILAGICLGYL 630
YL W D I ++ + LG++ L V ++F +TPVVKSS +CY+IL L +
Sbjct: 586 YLNWNDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFA 645
Query: 631 CTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSA 690
T I +P+ C ++ G+S + S ++TK+ +I +LA S K +F+
Sbjct: 646 STSFFIGEPQDFTCKTRQTMFGVSFTLCISCILTKSLKI--LLAFS---FDPKLQKFLK- 699
Query: 691 CAQLVIAFILIC--IQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTN-LGVVTPLGYN 747
C I I C IQ+ I I P + + R + L C + L T LGY
Sbjct: 700 CLYRPILIIFTCTGIQVVICTLWLIFAAPTVEVNVSLPRVIILECEEGSILAFGTMLGYI 759
Query: 748 GLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIY---FGSNYKIITMCF 804
+L C +AFK + N+NEAK+I F M I W+ F+PIY FG Y
Sbjct: 760 AILAFICFIFAFKGKY--ENYNEAKFITFGMLIYFIAWITFIPIYATTFG-KYVPAVEII 816
Query: 805 SVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVN 864
+ +S L C F+PK Y+I+ K E N +SAF ++ + SS A S +S
Sbjct: 817 VILISNYGILYCTFIPKCYVIICKQEINTKSAFL--KMIYSYSSHSVSSIALSPAS---- 870
Query: 865 LWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMGNGGRATMSSSNGKSVTWAQNEKSS 924
SM T SS+GKS TW
Sbjct: 871 -------------------------------LDSMSGNVTMTNPSSSGKSATW------Q 893
Query: 925 RGQHLWQRLSIHINKKENPNQTAVIKPFPKSTES 958
+ + L + HI ++ N T+V K P+ S
Sbjct: 894 KSKDLQAQAFAHICRE---NATSVSKTLPRKRMS 924
>gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens]
Length = 841
Score = 259 bits (661), Expect = 1e-68
Identities = 229/846 (27%), Positives = 381/846 (45%), Gaps = 85/846 (10%)
Query: 31 MPGDIIIGALFSVH-------HQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDP 83
+PGD ++ LF +H H+P V + +R C ++G +AM +E IN+
Sbjct: 34 LPGDYLLAGLFPLHSGCLQVRHRPEVT-LCDRSCSF--NEHGYHLFQAMRLGVEEINNST 90
Query: 84 TLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPI 143
LLPNITLG ++ D C SA +R + + ++ +
Sbjct: 91 ALLPNITLGYQLYDVCSDSANVYAT----LRVLSLPGQHH------IELQGDLLHYSPTV 140
Query: 144 VGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMV 203
+ VIGP S++ A LL F +P I+Y+A+S LS K + F+R +P+D Q MV
Sbjct: 141 LAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQVETMV 200
Query: 204 DIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKK 263
+++++ WT++S V + +YG+ G++A ++ + +GICIA +K Q D+ ++
Sbjct: 201 LLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIA--FKDIMPFSAQVGDERMQC 258
Query: 264 LTSHLPK--ARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVT--DGYQR 319
L HL + A VV F R ++ L G+ + + S+ WA +T G QR
Sbjct: 259 LMRHLAQAGATVVVVFSSRQLARVFFESVVLTNLTGK-VWVASEAWALSRHITGVPGIQR 317
Query: 320 -EAVGGITIKLQS-PDVKWFDDYYL---KLRPETNHRNPWFQEFWQHRFQCRLEGFPQEN 374
V G+ I+ ++ P +K F++ Y K P H+ W
Sbjct: 318 IGMVLGVAIQKRAVPGLKAFEEAYARADKKAPRPCHKGSWCSS----------------- 360
Query: 375 SKYNKTCNSSLTLKTHHVQDSK---MGFVIN---AIYSMAYGLHNMQMSLCPGYAGLCDA 428
N+ C H + K M N A+Y++A+GLH Q+ C +G C
Sbjct: 361 ---NQLCRECQAFMAHTMPKLKAFSMSSAYNAYRAVYAVAHGLH--QLLGCA--SGACSR 413
Query: 429 MKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDY-FDYINVGSW 487
+ + +LLE + K +F + DT+ F++N D Y I+ + G + F + +W
Sbjct: 414 GR-VYPWQLLEQIHKVHFL-LHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTW 471
Query: 488 DNGELKMDDDEV-WSKKSN-IIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYV-- 543
+L +++ ++ W K N + +SVCS C +G +V+ G CC+ C PC ++
Sbjct: 472 SPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVV-TGFHHCCFECVPCGAGTFLNK 530
Query: 544 FDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFII 603
D Y C+ C W + C V +L + + L LL L +F
Sbjct: 531 SDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAW 590
Query: 604 YRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALV 663
+ DTPVV+S+ LC+++L + G + +P + C L++ L + S L
Sbjct: 591 HLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLT 650
Query: 664 TKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICI----QLGIIVALFIMEPPDI 719
++ ++ I K TK P F A Q A + + I QL I + ++ P
Sbjct: 651 VRSFQLIIIF-----KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLP 705
Query: 720 MHDYPSIRE-VYLICNTTN-LGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFT 777
+Y V L C TN LG + YNGLL +S ++ +++P N+NEAK + F+
Sbjct: 706 AREYQRFPHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFS 765
Query: 778 MYTTCIIWLAF---VPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVR 834
+ + W+AF +Y G M +S S + G F+PK Y+IL +P+ N
Sbjct: 766 LLFNFVSWIAFFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCRPDLNST 824
Query: 835 SAFTTS 840
F S
Sbjct: 825 EHFQAS 830
>gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]
Length = 839
Score = 226 bits (576), Expect = 1e-58
Identities = 218/852 (25%), Positives = 377/852 (44%), Gaps = 92/852 (10%)
Query: 30 HMPGDIIIGALFSVHH-----------QPTVDKVHERKCGAVREQYGIQRVEAMLHTLER 78
++PGD ++G LFS+H Q + K +E K G ++AM +E
Sbjct: 28 YLPGDYLLGGLFSLHANMKGIVHLNFLQVPMCKEYEVKV------IGYNLMQAMRFAVEE 81
Query: 79 INSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFI--RDSLISSEEEEGLVRCVDGSSSS 136
IN+D +LLP + LG EI D C+ S ++ + F+ D+L+ +E+ S+
Sbjct: 82 INNDSSLLPGVLLGYEIVDVCYISN-NVQPVLYFLAHEDNLLPIQEDY----------SN 130
Query: 137 FRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDA 196
+ S+ +V VIGP +S + V N L LF +PQI YSA S +L DK F +R PS
Sbjct: 131 YISR--VVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTTPSAD 188
Query: 197 QQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQS 256
AMV ++ + W ++ + + YG + + A+ ICIA + + Q+
Sbjct: 189 HHIEAMVQLMLHFRWNWIIVLVSSDTYGRDNGQLLGERVARRDICIAFQETLPTLQPNQN 248
Query: 257 F-DKLLKKLTSHLPK-----ARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWA-- 308
+ ++L + + K ARVV F +T+ + R G + + S+ WA
Sbjct: 249 MTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYHFFNEVLRQNFTGA-VWIASESWAID 307
Query: 309 -DRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRL 367
+++T+ GITI QS + P F EF + Q
Sbjct: 308 PVLHNLTELRHLGTFLGITI--QSVPI------------------PGFSEFREWGPQAGP 347
Query: 368 EGFPQENSKY--NKTCNSSL--TLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYA 423
+ + Y N+ C++ L TL + + V+ ++YS Y + + SL
Sbjct: 348 PPLSRTSQSYTCNQECDNCLNATLSFNTILRLSGERVVYSVYSAVYAVAHALHSLLGCDK 407
Query: 424 GLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYIN 483
C + + +LLE + K NFT + I FD GD EI+ + + + + +
Sbjct: 408 STC-TKRVVYPWQLLEEIWKVNFT-LLDHQIFFDPQGDVALHLEIVQW-QWDRSQNPFQS 464
Query: 484 VGSWD--NGELKMDDDEVWSKKSNII-RSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKEN 540
V S+ +LK D W +N I S+CS+ C+ GQ K G CC+ C C
Sbjct: 465 VASYYPLQRQLKNIQDISWHTINNTIPMSMCSKRCQSGQ-KKKPVGIHVCCFECIDCLPG 523
Query: 541 EYV---FDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFV 597
++ DEY C+AC W T C + +L W + IA + A LG L+TL +
Sbjct: 524 TFLNHTEDEYECQACPNNEWSYQSETSCFKRQLVFLEWHEAPTIAVALLAALGFLSTLAI 583
Query: 598 TVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAM 657
V+F + TP+V+S+ +C+++L + + Y+ + PK C ++ L +
Sbjct: 584 LVIFWRHFQTPIVRSAGGPMCFLMLTLLLVAYMVVPVYVGPPKVSTCLCRQALFPLCFTI 643
Query: 658 SYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQ-----LVIAFILICIQLGIIVALF 712
S + ++ +I K+ ++ PR S + + +AFI + + +++ +
Sbjct: 644 CISCIAVRSFQIVCAF-----KMASRFPRAYSYWVRYQGPYVSMAFITVLKMVIVVIGML 698
Query: 713 IMEPPDIMHDYPSIREVYLI-CNTT-NLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNE 770
P ++ ++ CN ++ + LL + +A+ + +P N+NE
Sbjct: 699 ATGLSPTTRTDPDDPKITIVSCNPNYRNSLLFNTSLDLLLSVVGFSFAYMGKELPTNYNE 758
Query: 771 AKYIAFTM---YTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILA 827
AK+I +M +T+ + F+ Y G I+ + +V ++LG F PK Y+IL
Sbjct: 759 AKFITLSMTFYFTSSVSLCTFMSAYSGVLVTIVDLLVTVLNLLAISLG-YFGPKCYMILF 817
Query: 828 KPERNVRSAFTT 839
PERN + F +
Sbjct: 818 YPERNTPAYFNS 829
>gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo
sapiens]
Length = 254
Score = 198 bits (503), Expect = 3e-50
Identities = 113/236 (47%), Positives = 153/236 (64%), Gaps = 17/236 (7%)
Query: 632 TFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSAC 691
TF IAKP C L+R+G+G + ++ YSAL+TKTNRIARI G+++ ++PRF+S
Sbjct: 2 TFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREG--AQRPRFISPA 59
Query: 692 AQLVIAFILICIQLGIIVALFIMEPPDIMHDY-PSIREVYLI-CNTTNLGVVTPLGYNGL 749
+Q+ I LI QL I+VA ++E P + P REV + CN + ++ L YN L
Sbjct: 60 SQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVL 119
Query: 750 LILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYF--GSNYKI--ITMCFS 805
LI CT YAFKTR P NFNEAK+I FTMYTTCIIWLAF+PI++ S+Y++ TMC S
Sbjct: 120 LIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVS 179
Query: 806 VSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSS 861
VSLS +V LGC+F PK++IIL +P++N VV + SAA+R+SS
Sbjct: 180 VSLSGSVVLGCLFAPKLHIILFQPQKN---------VVSHRAPTSRFGSAAARASS 226
>gi|29294619 sweet taste receptor T1r isoform c [Homo sapiens]
Length = 587
Score = 144 bits (362), Expect = 7e-34
Identities = 113/418 (27%), Positives = 190/418 (45%), Gaps = 22/418 (5%)
Query: 437 LLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDY-FDYINVGSWDNGELKMD 495
LLE + K +F + DT+ F++N D Y I+ + G + F + +W +L ++
Sbjct: 167 LLEQIHKVHFL-LHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNIN 225
Query: 496 DDEV-WSKKSNII-RSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYV--FDEYTCKA 551
+ ++ W K N + +SVCS C +G +V+ G CC+ C PC ++ D Y C+
Sbjct: 226 ETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT-GFHHCCFECVPCGAGTFLNKSDLYRCQP 284
Query: 552 CQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVK 611
C W + C V +L + + L LL L +F + DTPVV+
Sbjct: 285 CGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVR 344
Query: 612 SSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIAR 671
S+ LC+++L + G + +P + C L++ L + S L ++ ++
Sbjct: 345 SAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLII 404
Query: 672 ILAGSKKKICTKKPRFMSACAQLVIAFILICI----QLGIIVALFIMEPPDIMHDYPSIR 727
I K TK P F A Q A + + I QL I + ++ P +Y
Sbjct: 405 IF-----KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFP 459
Query: 728 EVYLI-CNTTN-LGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIW 785
+ ++ C TN LG + YNGLL +S ++ +++P N+NEAK + F++ + W
Sbjct: 460 HLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSW 519
Query: 786 LAF---VPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS 840
+AF +Y G M +S S + G F+PK Y+IL +P+ N F S
Sbjct: 520 IAFFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCRPDLNSTEHFQAS 576
Score = 50.1 bits (118), Expect = 1e-05
Identities = 40/147 (27%), Positives = 65/147 (44%), Gaps = 20/147 (13%)
Query: 31 MPGDIIIGALFSVH-------HQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDP 83
+PGD ++ LF +H H+P V + +R C ++G +AM +E IN+
Sbjct: 34 LPGDYLLAGLFPLHSGCLQVRHRPEVT-LCDRSCSF--NEHGYHLFQAMRLGVEEINNST 90
Query: 84 TLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPI 143
LLPNITLG ++ D C SA +R + + ++ +
Sbjct: 91 ALLPNITLGYQLYDVCSDSA----NVYATLRVLSLPGQHH------IELQGDLLHYSPTV 140
Query: 144 VGVIGPGSSSVAIQVQNLLQLFNIPQI 170
+ VIGP S++ A LL F +P +
Sbjct: 141 LAVIGPDSTNRAATTAALLSPFLVPML 167
>gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens]
Length = 480
Score = 128 bits (321), Expect = 4e-29
Identities = 110/406 (27%), Positives = 184/406 (45%), Gaps = 58/406 (14%)
Query: 31 MPGDIIIGALFSVH-------HQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDP 83
+PGD ++ LF +H H+P V + +R C ++G +AM +E IN+
Sbjct: 34 LPGDYLLAGLFPLHSGCLQVRHRPEVT-LCDRSCSF--NEHGYHLFQAMRLGVEEINNST 90
Query: 84 TLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPI 143
LLPNITLG ++ D C SA +R + + ++ +
Sbjct: 91 ALLPNITLGYQLYDVCSDSANVYAT----LRVLSLPGQHH------IELQGDLLHYSPTV 140
Query: 144 VGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMV 203
+ VIGP S++ A LL F +P I+Y+A+S LS K + F+R +P+D Q MV
Sbjct: 141 LAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQVETMV 200
Query: 204 DIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKK 263
+++++ WT++S V + +YG+ G++A ++ + +GICIA +K Q D+ ++
Sbjct: 201 LLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIA--FKDIMPFSAQVGDERMQC 258
Query: 264 LTSHLPK--ARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVT--DGYQR 319
L HL + A VV F R ++ L G+ + + S+ WA +T G QR
Sbjct: 259 LMRHLAQAGATVVVVFSSRQLARVFFESVVLTNLTGK-VWVASEAWALSRHITGVPGIQR 317
Query: 320 -EAVGGITIKLQS-PDVKWFDDYYL---KLRPETNHRNPWFQEFWQHRFQCRLEGFPQEN 374
V G+ I+ ++ P +K F++ Y K P H+ W
Sbjct: 318 IGMVLGVAIQKRAVPGLKAFEEAYARADKKAPRPCHKGSWCSS----------------- 360
Query: 375 SKYNKTCNSSLTLKTHHVQDSK---MGFVIN---AIYSMAYGLHNM 414
N+ C H + K M N A+Y++A+GLH +
Sbjct: 361 ---NQLCRECQAFMAHTMPKLKAFSMSSAYNAYRAVYAVAHGLHQL 403
>gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]
Length = 852
Score = 126 bits (317), Expect = 1e-28
Identities = 116/454 (25%), Positives = 201/454 (44%), Gaps = 33/454 (7%)
Query: 400 VINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDEN 459
V A+YS+A LHN G C A P+ +LLE++ F V G + FD +
Sbjct: 393 VYAAVYSVAQALHNTLQCNASG----CPAQDPVKPWQLLENMYNLTFH-VGGLPLRFDSS 447
Query: 460 GDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEV-WSKKSNIIR-SVCSEPCEK 517
G+ Y++ + G + +VG + NG L+ + ++ W N S CS C++
Sbjct: 448 GNVDMEYDLKLWVWQGSVPRLH-DVGRF-NGSLRTERLKIRWHTSDNQKPVSRCSRQCQE 505
Query: 518 GQIKVIRKGEVSCCWTCTPCKENEYVF--DEYTCKACQLGSWPTDDLTGCDLIPVQYLRW 575
GQ++ + KG SCC+ C C+ Y D+ C C W + T C ++L W
Sbjct: 506 GQVRRV-KGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAW 564
Query: 576 GDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCL 635
G+P + ++ L L L +F+ +RD+P+V++S L L +CLG +C L
Sbjct: 565 GEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGL--VCLGLVCLSVL 622
Query: 636 I--AKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQ 693
+ +P C Q+ LS L T + A I S+ + +S C +
Sbjct: 623 LFPGQPSPARCLAQQ---PLSHLPLTGCLSTLFLQAAEIFVESELPLSWADR--LSGCLR 677
Query: 694 LVIAFILICIQLGIIVAL----FIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGY--N 747
A++++ + + + VAL + PP+++ D+ + L+ T V L + N
Sbjct: 678 GPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHCRTRSWVSFGLAHATN 737
Query: 748 GLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKII----TMC 803
L C F R+ P +N A+ + F M I W++FVP+ +N +++
Sbjct: 738 ATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLL--ANVQVVLRPAVQM 795
Query: 804 FSVSLSATVALGCMFVPKVYIILAKPERNVRSAF 837
++ L L +P+ Y+++ +P N F
Sbjct: 796 GALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFF 829
Score = 102 bits (255), Expect = 2e-21
Identities = 65/219 (29%), Positives = 108/219 (49%), Gaps = 15/219 (6%)
Query: 31 MPGDIIIGALFSVHHQPTVD-KVHERKCGAVREQY---GIQRVEAMLHTLERINSDPTLL 86
M GD ++G LF + + R V ++ G+ AM +E IN+ LL
Sbjct: 31 MKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSDLL 90
Query: 87 PNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKP-IVG 145
P + LG ++ D+C VA++ S+ F L + + C ++ +P ++
Sbjct: 91 PGLRLGYDLFDTCSEPVVAMKPSLMF----LAKAGSRDIAAYC------NYTQYQPRVLA 140
Query: 146 VIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDI 205
VIGP SS +A+ F +PQ++Y A+ LS + F F R VPSD Q A ++
Sbjct: 141 VIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAEL 200
Query: 206 VKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAH 244
++ + W +V+A+ ++ YG G+ F ++A GICIAH
Sbjct: 201 LQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAH 239
>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
Length = 941
Score = 65.5 bits (158), Expect = 3e-10
Identities = 88/330 (26%), Positives = 142/330 (43%), Gaps = 41/330 (12%)
Query: 589 LGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFC-------LIAKPKQ 641
LG++ I R+ ++K SS + +I+ G L Y F + K +
Sbjct: 491 LGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFE 550
Query: 642 IYCYLQRIGIGLSPAMSYSALVTKTNRIARILAG--SKKKICTKKPRFMSACAQLVIAF- 698
C ++ + + ++ A+ KT R+ I KKKI + + L+I
Sbjct: 551 TLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLIDLC 610
Query: 699 ILICIQ----LGIIVALFIMEPPDIMHDYPSIREVYLICNTTN----LGVVTPLGYNGLL 750
ILIC Q L V + MEP D SIR + C T+ LG+V Y GLL
Sbjct: 611 ILICWQAVDPLRRTVEKYSMEPDPAGRDI-SIRPLLEHCENTHMTIWLGIV--YAYKGLL 667
Query: 751 ILSCTFYAFKTRNV--PANFNEAKYIAFTMYTTCIIWLAFVPIYF----GSNYKIITMCF 804
+L F A++TRNV PA N++KYI ++Y I+ + + F N + +
Sbjct: 668 MLFGCFLAWETRNVSIPA-LNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVAL 726
Query: 805 SVSLSATVALGCMFVPKVYIILAKPE---RNVRSAFTTSTVVRMHVGDGKSSSAASRSSS 861
+ +T+ L +FVPK+ + P+ +N R FT + K S S S +
Sbjct: 727 VIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQN--------QKKEDSKTSTSVT 778
Query: 862 LVNLWKRRGSSGETLRYKDRRLAQHKSEIE 891
VN + S E L+ ++ RL +E++
Sbjct: 779 SVN--QASTSRLEGLQSENHRLRMKITELD 806
Score = 48.1 bits (113), Expect = 5e-05
Identities = 25/72 (34%), Positives = 40/72 (55%)
Query: 146 VIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDI 205
V G SV + LQ +N+ Q++++AT+ L+DK + YF R VPSD A++ +
Sbjct: 130 VFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKL 189
Query: 206 VKRYNWTYVSAV 217
+K Y W V +
Sbjct: 190 LKHYQWKRVGTL 201
>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
precursor [Homo sapiens]
Length = 899
Score = 55.8 bits (133), Expect = 2e-07
Identities = 179/913 (19%), Positives = 344/913 (37%), Gaps = 171/913 (18%)
Query: 1 MVLLLILSVLLLKEDVRGSAQS----SERRVVAHMPGD-------IIIGALFSVHHQPTV 49
M+LLL+L+ L L+ G AQ+ SE + H P + + + +++ P V
Sbjct: 1 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLP-V 59
Query: 50 DKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIR----------DSC 99
D E C RE G + + + + P+ N T E R
Sbjct: 60 DYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVNRTPHSERRAVYIGALFPMSGG 119
Query: 100 WHSAVALEQSIEFIRDSLISSEE-----EEGLV----RCVDGSSSSFRSK----KPIVGV 146
W A + ++E + + S + E L+ +C G ++ + + PI +
Sbjct: 120 WPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKII 179
Query: 147 IGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIV 206
+ PG SSV+ V +++N+ ++Y ++S LS++ F F R PS V +
Sbjct: 180 LMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLF 239
Query: 207 KRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTS 266
+++ W ++ + S ++ ++ + GI I +S+ K LK+ +
Sbjct: 240 EKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPV--KNLKRQDA 297
Query: 267 HL-------PKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLG--SDGWADRYD----- 312
+ +AR V FCE + R G + L+G +D W YD
Sbjct: 298 RIIVGLFYETEARKV--FCE-------VYKERLFGKKYVWFLIGWYADNWFKIYDPSINC 348
Query: 313 VTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHR--NPWFQEFWQHRFQCRLEGF 370
D G IT ++ + L P N QEF + + RL+
Sbjct: 349 TVDEMTEAVEGHITTEI------------VMLNPANTRSISNMTSQEFVE-KLTKRLKRH 395
Query: 371 PQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMK 430
P+E + Q++ + + +AI+++A L+ + S G +G+
Sbjct: 396 PEETGGF---------------QEAPLAY--DAIWALALALN--KTSGGGGRSGVRLEDF 436
Query: 431 PIDGRKLLESLMK----TNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGS 486
+ + + + + + ++F GVSG ++FD +G S + ++ + G Y +G
Sbjct: 437 NYNNQTITDQIYRAMNSSSFEGVSGH-VVFDASG-SRMAWTLIEQLQGGS----YKKIGY 490
Query: 487 WDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDE 546
+D+ + DD WSK I S P ++ + K ++ +
Sbjct: 491 YDSTK----DDLSWSKTDKWIGG--SPPADQTLV----------------IKTFRFLSQK 528
Query: 547 YTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRD 606
L S +V A + L ++ + V I
Sbjct: 529 LFISVSVLSS-------------------------LGIVLAVVCLSFNIYNSHVRYIQNS 563
Query: 607 TPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKT 666
P + + + C + LA + L + + C + +GL ++ Y ++ TK
Sbjct: 564 QPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTKI 623
Query: 667 NRIARILAGSKKKICTKK---PRFMSACAQLVIAFILICIQLGIIV-------ALFIMEP 716
+ + ++K +K P + A L++ ++ + + IV F E
Sbjct: 624 WWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEE 683
Query: 717 PDIMHDY---PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA-NFNEAK 772
P D P + T LG+ GY GLL+L F A++T++V N+ +
Sbjct: 684 PKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKSVSTEKINDHR 741
Query: 773 YIAFTMYTTCIIWLAFVPI-YFGSNYKIITMCF---SVSLSATVALGCMFVPKVYIILAK 828
+ +Y ++ L P+ S+ + F ++ S+ + L +FVPK+ ++ +
Sbjct: 742 AVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITR 801
Query: 829 PERNVRSAFTTST 841
E + T T
Sbjct: 802 GEWQSEAQDTMKT 814
>gi|93204867 G protein-coupled receptor 158 [Homo sapiens]
Length = 1215
Score = 55.1 bits (131), Expect = 4e-07
Identities = 77/355 (21%), Positives = 141/355 (39%), Gaps = 37/355 (10%)
Query: 545 DEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIY 604
+ Y C C+ G D + C + +YLR +A + F L +L +V +
Sbjct: 388 EAYVCLPCREGCPFCADDSPCFVQEDKYLR------LAIISFQALCMLLDFVSMLVVYHF 441
Query: 605 RDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVT 664
R +++S L IL G L Y L +P C L R L A Y +
Sbjct: 442 RKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGTVTL 501
Query: 665 KTNRIARI-LAGSKKKICT----KKPRFMSACAQLVIAFIL-----ICIQLGIIVALFIM 714
K +R+ ++ L+ + ++I + R ++ +V F++ +C L ++L
Sbjct: 502 KLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWFLIGWTSSVCQNLEKQISL--- 558
Query: 715 EPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYI 774
I S ++ +C +T + L +L + + R VP+ F+E +Y+
Sbjct: 559 ----IGQGKTSDHLIFNMCLIDRWDYMTAVA-EFLFLLWGVYLCYAVRTVPSAFHEPRYM 613
Query: 775 AFTMYTTCIIWLAFVPIYF------GSNYKIITMCFSVSLSATVALGCMFVPKVYIILAK 828
A ++ II F I F S++ ++ L+ TV +G + +PK +
Sbjct: 614 AVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIGLLLIPK----FSH 669
Query: 829 PERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRL 883
N R T + G+S S +SS+ + W E +R + ++L
Sbjct: 670 SSNNPRDDIATE-AYEDELDMGRSGSYL--NSSINSAWSEHSLDPEDIRDELKKL 721
>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
precursor [Homo sapiens]
Length = 844
Score = 53.5 bits (127), Expect = 1e-06
Identities = 144/738 (19%), Positives = 280/738 (37%), Gaps = 136/738 (18%)
Query: 142 PIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARA 201
PI ++ PG SSV+ V +++N+ ++Y ++S LS++ F F R PS
Sbjct: 120 PIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPT 179
Query: 202 MVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLL 261
V + +++ W ++ + S ++ ++ + GI I +S+ K L
Sbjct: 180 RVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPV--KNL 237
Query: 262 KKLTSHL-------PKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLG--SDGWADRYD 312
K+ + + +AR V FCE + R G + L+G +D W YD
Sbjct: 238 KRQDARIIVGLFYETEARKV--FCE-------VYKERLFGKKYVWFLIGWYADNWFKIYD 288
Query: 313 -----VTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHR--NPWFQEFWQHRFQC 365
D G IT ++ + L P N QEF + +
Sbjct: 289 PSINCTVDEMTEAVEGHITTEI------------VMLNPANTRSISNMTSQEFVE-KLTK 335
Query: 366 RLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGL 425
RL+ P+E + Q++ + + +AI+++A L+ + S G +G+
Sbjct: 336 RLKRHPEETGGF---------------QEAPLAY--DAIWALALALN--KTSGGGGRSGV 376
Query: 426 CDAMKPIDGRKLLESLMK----TNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDY 481
+ + + + + + ++F GVSG ++FD +G S + ++ + G Y
Sbjct: 377 RLEDFNYNNQTITDQIYRAMNSSSFEGVSGH-VVFDASG-SRMAWTLIEQLQGGS----Y 430
Query: 482 INVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENE 541
+G +D+ + DD WSK I S P ++ + K
Sbjct: 431 KKIGYYDSTK----DDLSWSKTDKWIGG--SPPADQTLV----------------IKTFR 468
Query: 542 YVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVF 601
++ + L S +V A + L ++ + V
Sbjct: 469 FLSQKLFISVSVLSS-------------------------LGIVLAVVCLSFNIYNSHVR 503
Query: 602 IIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSA 661
I P + + + C + LA + L + + C + +GL ++ Y +
Sbjct: 504 YIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGS 563
Query: 662 LVTKTNRIARILAGSKKKICTKK---PRFMSACAQLVIAFILICIQLGIIV-------AL 711
+ TK + + ++K +K P + A L++ ++ + + IV
Sbjct: 564 MFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIET 623
Query: 712 FIMEPPDIMHDY---PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA-N 767
F E P D P + T LG+ GY GLL+L F A++T++V
Sbjct: 624 FAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKSVSTEK 681
Query: 768 FNEAKYIAFTMYTTCIIWLAFVPI-YFGSNYKIITMCF---SVSLSATVALGCMFVPKVY 823
N+ + + +Y ++ L P+ S+ + F ++ S+ + L +FVPK+
Sbjct: 682 INDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMR 741
Query: 824 IILAKPERNVRSAFTTST 841
++ + E + T T
Sbjct: 742 RLITRGEWQSEAQDTMKT 759
>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
precursor [Homo sapiens]
Length = 961
Score = 53.5 bits (127), Expect = 1e-06
Identities = 144/738 (19%), Positives = 280/738 (37%), Gaps = 136/738 (18%)
Query: 142 PIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARA 201
PI ++ PG SSV+ V +++N+ ++Y ++S LS++ F F R PS
Sbjct: 237 PIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPT 296
Query: 202 MVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLL 261
V + +++ W ++ + S ++ ++ + GI I +S+ K L
Sbjct: 297 RVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPV--KNL 354
Query: 262 KKLTSHL-------PKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLG--SDGWADRYD 312
K+ + + +AR V FCE + R G + L+G +D W YD
Sbjct: 355 KRQDARIIVGLFYETEARKV--FCE-------VYKERLFGKKYVWFLIGWYADNWFKIYD 405
Query: 313 -----VTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHR--NPWFQEFWQHRFQC 365
D G IT ++ + L P N QEF + +
Sbjct: 406 PSINCTVDEMTEAVEGHITTEI------------VMLNPANTRSISNMTSQEFVE-KLTK 452
Query: 366 RLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGL 425
RL+ P+E + Q++ + + +AI+++A L+ + S G +G+
Sbjct: 453 RLKRHPEETGGF---------------QEAPLAY--DAIWALALALN--KTSGGGGRSGV 493
Query: 426 CDAMKPIDGRKLLESLMK----TNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDY 481
+ + + + + + ++F GVSG ++FD +G S + ++ + G Y
Sbjct: 494 RLEDFNYNNQTITDQIYRAMNSSSFEGVSGH-VVFDASG-SRMAWTLIEQLQGGS----Y 547
Query: 482 INVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENE 541
+G +D+ + DD WSK I S P ++ + K
Sbjct: 548 KKIGYYDSTK----DDLSWSKTDKWIGG--SPPADQTLV----------------IKTFR 585
Query: 542 YVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVF 601
++ + L S +V A + L ++ + V
Sbjct: 586 FLSQKLFISVSVLSS-------------------------LGIVLAVVCLSFNIYNSHVR 620
Query: 602 IIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSA 661
I P + + + C + LA + L + + C + +GL ++ Y +
Sbjct: 621 YIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFSLGYGS 680
Query: 662 LVTKTNRIARILAGSKKKICTKK---PRFMSACAQLVIAFILICIQLGIIV-------AL 711
+ TK + + ++K +K P + A L++ ++ + + IV
Sbjct: 681 MFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIET 740
Query: 712 FIMEPPDIMHDY---PSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPA-N 767
F E P D P + T LG+ GY GLL+L F A++T++V
Sbjct: 741 FAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIF--YGYKGLLLLLGIFLAYETKSVSTEK 798
Query: 768 FNEAKYIAFTMYTTCIIWLAFVPI-YFGSNYKIITMCF---SVSLSATVALGCMFVPKVY 823
N+ + + +Y ++ L P+ S+ + F ++ S+ + L +FVPK+
Sbjct: 799 INDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMR 858
Query: 824 IILAKPERNVRSAFTTST 841
++ + E + T T
Sbjct: 859 RLITRGEWQSEAQDTMKT 876
>gi|29294621 sweet taste receptor T1r isoform d [Homo sapiens]
Length = 324
Score = 53.5 bits (127), Expect = 1e-06
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 6/121 (4%)
Query: 437 LLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDY-FDYINVGSWDNGELKMD 495
LLE + K +F + DT+ F++N D Y I+ + G + F + +W +L ++
Sbjct: 167 LLEQIHKVHFL-LHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNIN 225
Query: 496 DDEV-WSKKSNII-RSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYT-CKAC 552
+ ++ W K N + +SVCS C +G +V+ G CC+ C PC ++ T + C
Sbjct: 226 ETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT-GFHHCCFECVPCGAGTFLNKSATWVRTC 284
Query: 553 Q 553
Q
Sbjct: 285 Q 285
Score = 50.1 bits (118), Expect = 1e-05
Identities = 40/147 (27%), Positives = 65/147 (44%), Gaps = 20/147 (13%)
Query: 31 MPGDIIIGALFSVH-------HQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDP 83
+PGD ++ LF +H H+P V + +R C ++G +AM +E IN+
Sbjct: 34 LPGDYLLAGLFPLHSGCLQVRHRPEVT-LCDRSCSF--NEHGYHLFQAMRLGVEEINNST 90
Query: 84 TLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPI 143
LLPNITLG ++ D C SA +R + + ++ +
Sbjct: 91 ALLPNITLGYQLYDVCSDSA----NVYATLRVLSLPGQHH------IELQGDLLHYSPTV 140
Query: 144 VGVIGPGSSSVAIQVQNLLQLFNIPQI 170
+ VIGP S++ A LL F +P +
Sbjct: 141 LAVIGPDSTNRAATTAALLSPFLVPML 167
>gi|93352554 GPR158-like 1 [Homo sapiens]
Length = 2367
Score = 51.6 bits (122), Expect = 4e-06
Identities = 72/323 (22%), Positives = 118/323 (36%), Gaps = 26/323 (8%)
Query: 549 CKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLG--LLATLFVTVVFIIYRD 606
C C G D T C + LR A V AC +LA +V R
Sbjct: 356 CLPCPEGCTSCMDATPCLVEEAAVLR--------AAVLACQACCMLAIFLSMLVSYRCRR 407
Query: 607 TPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKT 666
+ +S L +L G L Y F L KP C R L A+ Y ++ K
Sbjct: 408 NKRIWASGVVLLETVLFGFLLLYFPVFILYFKPSVFRCIALRWVRLLGFAIVYGTIILKL 467
Query: 667 NRIARILAG--SKKKICTKKPRFMSACAQLVIAFI--LICIQLGIIVALFIMEPPDIMHD 722
R+ ++ +++ R + L++ + L +G + P I
Sbjct: 468 YRVLQLFLSRTAQRSALLSSGRLLRRLGLLLLPVLGFLAVWTVGALERGIQHAPLVIRGH 527
Query: 723 YPSIREVYLICNTTNLGVVTPLGYNGLLILSC--TFYAFKTRNVPANFNEAKYIAFTMYT 780
PS R YL C+ + + L+L C +F + TR V + F+E +Y+ ++
Sbjct: 528 TPSGRHFYL-CHHDRWDYIMVVAE---LLLLCWGSFLCYATRAVLSAFHEPRYMGIALHN 583
Query: 781 TCIIWLAFVPIYF------GSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVR 834
++ AF F ++ ++ F + T L +F+PK + + A P +
Sbjct: 584 ELLLSAAFHTARFVLVPSLHPDWTLLLFFFHTHSTVTTTLALIFIPKFWKLGAPPREEMV 643
Query: 835 SAFTTSTVVRMHVGDGKSSSAAS 857
+ H G SS AS
Sbjct: 644 DEVCEDELDLQHSGSYLGSSIAS 666
>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
Length = 518
Score = 48.1 bits (113), Expect = 5e-05
Identities = 60/212 (28%), Positives = 81/212 (38%), Gaps = 22/212 (10%)
Query: 968 GGSAGGVGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPSPISTLSH 1027
G + V A G P PD P A ++ H P PA +P +TL
Sbjct: 244 GSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRV--NHEPEPAGGATPG--ATLP- 298
Query: 1028 RAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVT-RFTANISELN-SMMLSTAAP 1085
++ S R VP P + + S+ EQI S+ F IS S + A
Sbjct: 299 KSPSQLRKGPPVP-----PPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPTESPAG 353
Query: 1086 SPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAARESPA 1145
S G P + + P+ QP A EV GG QPAAGAQ G+ A
Sbjct: 354 SLPSGEPSAAEGTFA--VSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETA----- 406
Query: 1146 AGPEAAAAKPDLEELVALTPPSPFRDSVDSGS 1177
+ AA L +V T P+ +V+ GS
Sbjct: 407 ---ASEAASSSLPAVVVETFPATVNGTVEGGS 435
>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
Length = 332
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/119 (29%), Positives = 49/119 (41%), Gaps = 10/119 (8%)
Query: 960 GLGAGAGAGGSAGGVGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSP 1019
G G G GAGG +GG GG G GAG GG A P+ L F P SP
Sbjct: 37 GAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGSRAPPEEL-------SMFQLPTLNFSP 89
Query: 1020 SPISTLS---HRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISEL 1075
++++ G R + SL P A + ++ + + +VV T N +L
Sbjct: 90 EQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDL 148
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 45.8 bits (107), Expect = 2e-04
Identities = 55/233 (23%), Positives = 85/233 (36%), Gaps = 21/233 (9%)
Query: 983 AGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPSPISTLSHRAGSASR--TDDDVP 1040
A P E+P L + AEE A A +SP T + A + + + P
Sbjct: 478 AATEPPADETPAEARSPLSEETSAEE---AHAEVQSPLAEETTAEEASAEIQLLAAIEAP 534
Query: 1041 SLHSEPVARSSSSQGSLMEQISSVVTRFTANISELNSMMLSTAAPSPG------------ 1088
+ + A+S S+ + E+ + V +A + L PS
Sbjct: 535 ADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQ 594
Query: 1089 -VGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAARESPAAG 1147
+ A S+ P E+Q P AE+QP PA E QP +A + + PA
Sbjct: 595 LLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAE-VQPPPAEE 653
Query: 1148 PEAAAAKPDLEELVALTPPSPFRDSVDSGSTTP--NSPVSESALCIPSSPKYD 1198
A P EE A P P ++ + P +P+ E+ + S P D
Sbjct: 654 APAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADD 706
Score = 37.7 bits (86), Expect = 0.067
Identities = 51/181 (28%), Positives = 69/181 (38%), Gaps = 20/181 (11%)
Query: 987 PGGPESPDAGPKALYDVAEAEEHFPAPARPRSPSPISTLSHRAGSASRTDDDVPSLHSEP 1046
P ESP P A E P PA +SPS R+ SA + +V L +E
Sbjct: 353 PSAEESPSEEPPA--------EILPPPAE-KSPSVELLGEIRSPSAQKAPIEVQPLPAEG 403
Query: 1047 VARSSSSQ---GSLMEQISSVVTRFT--ANISELNSMMLSTAAPSPGVGAPLCSSYLIPK 1101
+ ++ ++ E ++ V A E + LSTA +P AP +PK
Sbjct: 404 ALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSPLPK 463
Query: 1102 EIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAARESPAAGPEAAAAKPDLEELV 1161
E T AEIQ L A E P A+A + E+ A A P EE
Sbjct: 464 E---TTAEEASAEIQLLAATEPPADETP---AEARSPLSEETSAEEAHAEVQSPLAEETT 517
Query: 1162 A 1162
A
Sbjct: 518 A 518
Score = 31.2 bits (69), Expect = 6.3
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 1095 SSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAA----GAQAAGDAARESPAAGPEA 1150
S+ P +IQ P A+ +P PA E QP+ A+AA A S P
Sbjct: 261 STEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPP 320
Query: 1151 AAAKPDLEELVALTPPS 1167
A P +E + PPS
Sbjct: 321 AEEAPLVEFPAEIQPPS 337
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,158,567
Number of Sequences: 37866
Number of extensions: 2399089
Number of successful extensions: 19543
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 181
Number of HSP's successfully gapped in prelim test: 405
Number of HSP's that attempted gapping in prelim test: 13936
Number of HSP's gapped (non-prelim): 3956
length of query: 1212
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1098
effective length of database: 13,930,794
effective search space: 15296011812
effective search space used: 15296011812
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.