Guide to the Human Genome
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Search of human proteins with 219842262

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|219842262 COP9 constitutive photomorphogenic homolog subunit
2 isoform 2 [Homo sapiens]
         (450 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219842262 COP9 constitutive photomorphogenic homolog subunit ...   904   0.0  
gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2 ...   881   0.0  
gi|28872725 proteasome 26S non-ATPase subunit 11 [Homo sapiens]       114   1e-25
gi|47078240 G protein pathway suppressor 1 isoform 2 [Homo sapiens]    46   8e-05
gi|47078238 G protein pathway suppressor 1 isoform 1 [Homo sapiens]    46   8e-05
gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo ...    41   0.003
gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo...    41   0.003
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]          38   0.016
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    37   0.048
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    37   0.048
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    37   0.048
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    37   0.048
gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ...    36   0.062
gi|54607116 leiomodin 3 (fetal) [Homo sapiens]                         35   0.18 
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap...    34   0.24 
gi|4503521 eukaryotic translation initiation factor 3, subunit 6...    34   0.31 
gi|23397429 eukaryotic translation initiation factor 3, subunit ...    33   0.40 
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               33   0.40 
gi|12232385 COP9 constitutive photomorphogenic homolog subunit 7...    33   0.40 
gi|7661914 proteasome (prosome, macropain) 26S subunit, non-ATPa...    33   0.40 
gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi...    32   1.2  
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     32   1.2  
gi|32698688 citron [Homo sapiens]                                      32   1.5  
gi|27734905 aprataxin and PNKP like factor [Homo sapiens]              32   1.5  
gi|189217904 RPGRIP1-like isoform b [Homo sapiens]                     32   1.5  
gi|118442834 RPGRIP1-like isoform a [Homo sapiens]                     32   1.5  
gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo ...    31   2.6  
gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo ...    31   2.6  
gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]              31   2.6  
gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]              31   2.6  

>gi|219842262 COP9 constitutive photomorphogenic homolog subunit 2
           isoform 2 [Homo sapiens]
          Length = 450

 Score =  904 bits (2335), Expect = 0.0
 Identities = 450/450 (100%), Positives = 450/450 (100%)

Query: 1   MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 60
           MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL
Sbjct: 1   MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 60

Query: 61  EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 120
           EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS
Sbjct: 61  EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 120

Query: 121 TSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR 180
           TSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR
Sbjct: 121 TSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR 180

Query: 181 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI 240
           QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI
Sbjct: 181 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI 240

Query: 241 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP 300
           MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP
Sbjct: 241 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP 300

Query: 301 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN 360
           FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN
Sbjct: 301 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN 360

Query: 361 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH 420
           IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH
Sbjct: 361 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH 420

Query: 421 QKRGGARYTALDKWTNQLNSLNQAVVSKLA 450
           QKRGGARYTALDKWTNQLNSLNQAVVSKLA
Sbjct: 421 QKRGGARYTALDKWTNQLNSLNQAVVSKLA 450


>gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2
           isoform 1 [Homo sapiens]
          Length = 443

 Score =  881 bits (2277), Expect = 0.0
 Identities = 443/450 (98%), Positives = 443/450 (98%), Gaps = 7/450 (1%)

Query: 1   MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 60
           MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL
Sbjct: 1   MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 60

Query: 61  EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 120
           EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS
Sbjct: 61  EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 120

Query: 121 TSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR 180
           TSKQ       MDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR
Sbjct: 121 TSKQ-------MDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR 173

Query: 181 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI 240
           QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI
Sbjct: 174 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI 233

Query: 241 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP 300
           MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP
Sbjct: 234 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP 293

Query: 301 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN 360
           FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN
Sbjct: 294 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN 353

Query: 361 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH 420
           IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH
Sbjct: 354 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH 413

Query: 421 QKRGGARYTALDKWTNQLNSLNQAVVSKLA 450
           QKRGGARYTALDKWTNQLNSLNQAVVSKLA
Sbjct: 414 QKRGGARYTALDKWTNQLNSLNQAVVSKLA 443


>gi|28872725 proteasome 26S non-ATPase subunit 11 [Homo sapiens]
          Length = 422

 Score =  114 bits (286), Expect = 1e-25
 Identities = 102/387 (26%), Positives = 177/387 (45%), Gaps = 34/387 (8%)

Query: 49  AALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYS 108
           AA+  FQ+   L     E     L  ++K + +  N  E +   +Q +  + S + +   
Sbjct: 4   AAVVEFQRAQSLLSTDREASIDILHSIVKRDIQ-ENDEEAVQVKEQSILELGSLLAKTGQ 62

Query: 109 EKSINSILDYI-----STSKQNSDFLCQ--MDLLQEFYETT-------LEALKDAKNDRL 154
              +  +L Y+     S SK  +  L +  +DL  +    T       LE ++ AK+++ 
Sbjct: 63  AAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWAKSEKR 122

Query: 155 WF---KTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQM 211
            F       +L  LY + + Y +   +  QL +  +  D +        L+E+  LE + 
Sbjct: 123 TFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDK------ALLVEVQLLESKT 176

Query: 212 YTAQKNNKKLKALYEQSLHIKSAIP-HPLIMGVIRECGGKMHL-REGEFEKAHTDFFEAF 269
           Y A  N  K +A    +    +AI   P +   +    G +H   E +++ A++ F+EAF
Sbjct: 177 YHALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAF 236

Query: 270 KNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYK-----NDPEILAMTNLVSA 324
           + YD   SP+  T LKY++L  +++ +   P D Q     K        +  A+  +  A
Sbjct: 237 EGYDSIDSPKAITSLKYMLLCKIMLNT---PEDVQALVSGKLALRYAGRQTEALKCVAQA 293

Query: 325 YQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKE 384
            +N  + +FEK L    + + DDP I  H+ +L  N+  Q LI++I+P++R+ I  IS  
Sbjct: 294 SKNRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSL 353

Query: 385 LNIDVADVESLLVQCILDNTIHGRIDQ 411
           + +  ADVE  L Q ILD   HG +DQ
Sbjct: 354 IKLSKADVERKLSQMILDKKFHGILDQ 380


>gi|47078240 G protein pathway suppressor 1 isoform 2 [Homo sapiens]
          Length = 491

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 24/82 (29%), Positives = 41/82 (50%)

Query: 335 KILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVES 394
           K+L     N++ D ++  H+  L   IR + LI+   PY    +  ++   N  VA +E 
Sbjct: 343 KMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMHRMAAAFNTTVAALED 402

Query: 395 LLVQCILDNTIHGRIDQVNQLL 416
            L Q IL+  I  R+D  +++L
Sbjct: 403 ELTQLILEGLISARVDSHSKIL 424


>gi|47078238 G protein pathway suppressor 1 isoform 1 [Homo sapiens]
          Length = 527

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 24/82 (29%), Positives = 41/82 (50%)

Query: 335 KILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVES 394
           K+L     N++ D ++  H+  L   IR + LI+   PY    +  ++   N  VA +E 
Sbjct: 379 KMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMHRMAAAFNTTVAALED 438

Query: 395 LLVQCILDNTIHGRIDQVNQLL 416
            L Q IL+  I  R+D  +++L
Sbjct: 439 ELTQLILEGLISARVDSHSKIL 460


>gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo
           sapiens]
          Length = 456

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/319 (17%), Positives = 137/319 (42%), Gaps = 49/319 (15%)

Query: 163 GKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLK 222
           GK+Y+E E   +L K L  + +         D+K+   +L+   L+++ Y + +  ++++
Sbjct: 134 GKIYVEIER-ARLTKTLATIKEQ------NGDVKEAASILQ--ELQVETYGSMEKKERVE 184

Query: 223 ALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTT 282
            + EQ + +  A+   +   +I +       +E   EK    ++      D+      + 
Sbjct: 185 FILEQ-MRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSI 243

Query: 283 CLKYLV-----------------LANMLMKSGINPFDSQEAKPY------KNDPEILAMT 319
           C  Y                   L ++++   + PFD++++         K   EI    
Sbjct: 244 CKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYK 303

Query: 320 NLVSAYQNNDITEFEKILKTNHSNI----MDDPFI-----REHIEELLRNIRTQVL---I 367
           +L+  +   ++  +  +++     +    ++ P        E  E+  ++++ +V+   I
Sbjct: 304 DLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNI 363

Query: 368 KLI-KPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGA 426
           +++ K YTRI +  +++ L++ V + E+ L   +++ TI  ++D++  ++     K    
Sbjct: 364 RIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPN- 422

Query: 427 RYTALDKWTNQLNSLNQAV 445
               L+ W+ +LNSL   V
Sbjct: 423 --NLLNDWSQKLNSLMSLV 439


>gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo
           sapiens]
          Length = 436

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 56/319 (17%), Positives = 137/319 (42%), Gaps = 49/319 (15%)

Query: 163 GKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLK 222
           GK+Y+E E   +L K L  + +         D+K+   +L+   L+++ Y + +  ++++
Sbjct: 114 GKIYVEIER-ARLTKTLATIKEQ------NGDVKEAASILQ--ELQVETYGSMEKKERVE 164

Query: 223 ALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTT 282
            + EQ + +  A+   +   +I +       +E   EK    ++      D+      + 
Sbjct: 165 FILEQ-MRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSI 223

Query: 283 CLKYLV-----------------LANMLMKSGINPFDSQEAKPY------KNDPEILAMT 319
           C  Y                   L ++++   + PFD++++         K   EI    
Sbjct: 224 CKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYK 283

Query: 320 NLVSAYQNNDITEFEKILKTNHSNI----MDDPFI-----REHIEELLRNIRTQVL---I 367
           +L+  +   ++  +  +++     +    ++ P        E  E+  ++++ +V+   I
Sbjct: 284 DLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNI 343

Query: 368 KLI-KPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGA 426
           +++ K YTRI +  +++ L++ V + E+ L   +++ TI  ++D++  ++     K    
Sbjct: 344 RIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPN- 402

Query: 427 RYTALDKWTNQLNSLNQAV 445
               L+ W+ +LNSL   V
Sbjct: 403 --NLLNDWSQKLNSLMSLV 419


>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
          Length = 4646

 Score = 38.1 bits (87), Expect = 0.016
 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 15/137 (10%)

Query: 142 TLEALKDAK--NDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGT 199
           TL+ LK  K  +  + F T+T L +      +Y  L K           D   +DL   T
Sbjct: 300 TLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMK-----------DFPLNDLLSAT 348

Query: 200 QLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGK--MHLREGE 257
           +L +I    + ++T  +  +  K   +++L +  AI   L   +++  G +  MH+   E
Sbjct: 349 ELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEE 408

Query: 258 FEKAHTDFFEAFKNYDE 274
           FEK     FE F+ +D+
Sbjct: 409 FEKVMVACFEVFQTWDD 425


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 53/238 (22%), Positives = 97/238 (40%), Gaps = 34/238 (14%)

Query: 17   DLEYSEDSNSEPNVDLENQYYNSKALKEDD---------PKAALSSFQKVLELEGEKGEW 67
            DL+  ++ N E    L+ Q +  +   ED+          K  L    K LEL+ +    
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638

Query: 68   G-FKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNS 126
            G  +A+KQ+ K+  ++ +F   +   +     I +    N  EK   S+          +
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN--EKKAKSL---------EA 1687

Query: 127  DFLCQMDLLQEFYETTLEALK--DAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQ 184
            D +     LQE       A K  D + + L  +  + L      ++E  +L+  + QL +
Sbjct: 1688 DLM----QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1743

Query: 185  SCQTDDG-----EDDLKKGTQLLEIYALEI--QMYTAQKNNKKLKALYEQSLHIKSAI 235
              + + G      D ++K TQ  E  + E+  +  TAQKN    + L  Q+  ++S +
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 53/238 (22%), Positives = 97/238 (40%), Gaps = 34/238 (14%)

Query: 17   DLEYSEDSNSEPNVDLENQYYNSKALKEDD---------PKAALSSFQKVLELEGEKGEW 67
            DL+  ++ N E    L+ Q +  +   ED+          K  L    K LEL+ +    
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645

Query: 68   G-FKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNS 126
            G  +A+KQ+ K+  ++ +F   +   +     I +    N  EK   S+          +
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN--EKKAKSL---------EA 1694

Query: 127  DFLCQMDLLQEFYETTLEALK--DAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQ 184
            D +     LQE       A K  D + + L  +  + L      ++E  +L+  + QL +
Sbjct: 1695 DLM----QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1750

Query: 185  SCQTDDG-----EDDLKKGTQLLEIYALEI--QMYTAQKNNKKLKALYEQSLHIKSAI 235
              + + G      D ++K TQ  E  + E+  +  TAQKN    + L  Q+  ++S +
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 53/238 (22%), Positives = 97/238 (40%), Gaps = 34/238 (14%)

Query: 17   DLEYSEDSNSEPNVDLENQYYNSKALKEDD---------PKAALSSFQKVLELEGEKGEW 67
            DL+  ++ N E    L+ Q +  +   ED+          K  L    K LEL+ +    
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645

Query: 68   G-FKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNS 126
            G  +A+KQ+ K+  ++ +F   +   +     I +    N  EK   S+          +
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN--EKKAKSL---------EA 1694

Query: 127  DFLCQMDLLQEFYETTLEALK--DAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQ 184
            D +     LQE       A K  D + + L  +  + L      ++E  +L+  + QL +
Sbjct: 1695 DLM----QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1750

Query: 185  SCQTDDG-----EDDLKKGTQLLEIYALEI--QMYTAQKNNKKLKALYEQSLHIKSAI 235
              + + G      D ++K TQ  E  + E+  +  TAQKN    + L  Q+  ++S +
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 36.6 bits (83), Expect = 0.048
 Identities = 53/238 (22%), Positives = 97/238 (40%), Gaps = 34/238 (14%)

Query: 17   DLEYSEDSNSEPNVDLENQYYNSKALKEDD---------PKAALSSFQKVLELEGEKGEW 67
            DL+  ++ N E    L+ Q +  +   ED+          K  L    K LEL+ +    
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638

Query: 68   G-FKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNS 126
            G  +A+KQ+ K+  ++ +F   +   +     I +    N  EK   S+          +
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN--EKKAKSL---------EA 1687

Query: 127  DFLCQMDLLQEFYETTLEALK--DAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQ 184
            D +     LQE       A K  D + + L  +  + L      ++E  +L+  + QL +
Sbjct: 1688 DLM----QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1743

Query: 185  SCQTDDG-----EDDLKKGTQLLEIYALEI--QMYTAQKNNKKLKALYEQSLHIKSAI 235
              + + G      D ++K TQ  E  + E+  +  TAQKN    + L  Q+  ++S +
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801


>gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1
           [Homo sapiens]
          Length = 847

 Score = 36.2 bits (82), Expect = 0.062
 Identities = 38/158 (24%), Positives = 65/158 (41%), Gaps = 33/158 (20%)

Query: 1   MSDMEDDFMCDDEED-YDLEYSEDSNSEPNVDL--ENQYYNSKALKEDDPKAALSSFQKV 57
           + D+ D+ + +DEED YD  Y ED   E   DL    + +  K  + D     L+  ++ 
Sbjct: 144 LPDLIDETLVEDEEDLYDCVYGEDEGGEVYEDLMKAEEAHQPKCPENDIRSCCLAEIKQT 203

Query: 58  LELEGEKGE----WGFKALKQMI---KINFKLTNFPEMMNRYKQLLTYIRSAVTR----- 105
            E   E  E    +    LK+ +   + +    N PE++  ++ L+  I  ++       
Sbjct: 204 EEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQN 263

Query: 106 ------NYSEK------------SINSILDYISTSKQN 125
                 NY E+            S  S LDYIS +K++
Sbjct: 264 LYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKED 301


>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
          Length = 560

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 11/132 (8%)

Query: 5   EDDFMCDDEEDYDLEYSEDSNSEP---------NVDLENQYYNSKALKE--DDPKAALSS 53
           E+D   DDE + D E SE++N E          N +   Q    KA KE  D P+A   S
Sbjct: 150 EEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQS 209

Query: 54  FQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSIN 113
            +K+ +L+ +K       LK   + +   T+    + R ++    ++     N       
Sbjct: 210 EKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKELNLNNIENIPKE 269

Query: 114 SILDYISTSKQN 125
            +LD+++  K+N
Sbjct: 270 MLLDFVNAMKKN 281


>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
           sapiens]
          Length = 955

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 47/248 (18%), Positives = 111/248 (44%), Gaps = 32/248 (12%)

Query: 12  DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKA 71
           +++ +DL+   D   E      +++   +ALKE + +  L+   +V  L+ ++ +   + 
Sbjct: 550 EKKAHDLQSELDKGKEDTQKKIHKF--EEALKEKEEQ--LTRVTEVQRLQAQQADAALEE 605

Query: 72  LKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQNSDFLCQ 131
            K+ +++N +   + EM    K+ +  + + +TR+ S +            KQ+ +FL Q
Sbjct: 606 FKRQVELNSEKV-YAEM----KEQMEKVEADLTRSKSLRE-----------KQSKEFLWQ 649

Query: 132 MDLLQEFYETTLEALK-DAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDD 190
           ++ +++ YE  +  LK + + ++          K  L R+   +++ + +QL  +    +
Sbjct: 650 LEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHE 709

Query: 191 GEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI-MGVIRECGG 249
            +    K      I  +E Q++           L E+ +++ S     L+ +G++RE   
Sbjct: 710 NQIQEFKKRDAQVIADMEAQVH----------KLREELINVNSQRKQQLVELGLLREEEK 759

Query: 250 KMHLREGE 257
           +   RE E
Sbjct: 760 QRATREHE 767


>gi|4503521 eukaryotic translation initiation factor 3, subunit 6
           48kDa [Homo sapiens]
          Length = 445

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 6/108 (5%)

Query: 304 QEAKPYKNDPEILAMTNLVSA-YQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIR 362
           QE+  YK DP    +T  V   Y N D    +K L+   S +++D F+   +E+ + N R
Sbjct: 283 QESYTYK-DP----ITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENAR 337

Query: 363 TQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRID 410
             +     + +  I I  ++ +LN+   + E  +V  I +  +  +ID
Sbjct: 338 LFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKID 385


>gi|23397429 eukaryotic translation initiation factor 3, subunit M
           [Homo sapiens]
          Length = 374

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 19/100 (19%), Positives = 44/100 (44%), Gaps = 7/100 (7%)

Query: 355 EELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQ 414
           E+ +  +R    + +      I    + +EL I   DVE+ ++  +    ++ +IDQ  +
Sbjct: 271 EQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQR 330

Query: 415 LLELDH-------QKRGGARYTALDKWTNQLNSLNQAVVS 447
            + + H       +++    Y  L+ W   LN +  +++S
Sbjct: 331 KVVVSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLS 370


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 60/235 (25%), Positives = 95/235 (40%), Gaps = 34/235 (14%)

Query: 12   DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKG-----E 66
            + E + LE +   N E    +EN   + + L E+  K  L   Q   ++E EKG     +
Sbjct: 1061 ERELHKLEGNLKLNRE---SMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQ 1117

Query: 67   WGFKALKQMIK-INFKLT---NFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTS 122
               K L+  IK +  KL         M R +  LT   + +     E   +S+     T 
Sbjct: 1118 KTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITK 1177

Query: 123  KQNSDFLCQMDLLQE---FYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKIL 179
            KQ + F      ++E    +ETT  +LK    D L               E  G+++  L
Sbjct: 1178 KQETKFQKLHRDMEEATLHFETTSASLKKRHADSL--------------AELEGQVEN-L 1222

Query: 180  RQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSA 234
            +Q+ Q  + D  +  L+    L  +     QM  A+ N +KL  LYE+ LH  +A
Sbjct: 1223 QQVKQKLEKDKSDLQLEVDDLLTRVE----QMTRAKANAEKLCTLYEERLHEATA 1273


>gi|12232385 COP9 constitutive photomorphogenic homolog subunit 7B
           [Homo sapiens]
          Length = 264

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 16/45 (35%), Positives = 32/45 (71%), Gaps = 3/45 (6%)

Query: 378 IPF--ISKELNI-DVADVESLLVQCILDNTIHGRIDQVNQLLELD 419
           IP+  + K+L + ++ ++E L+++ +  + I G++DQ NQLLE+D
Sbjct: 111 IPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVD 155


>gi|7661914 proteasome (prosome, macropain) 26S subunit, non-ATPase,
           6 [Homo sapiens]
          Length = 389

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 17/85 (20%), Positives = 40/85 (47%)

Query: 333 FEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADV 392
           F + L      +  D     H    +R +R     +L++ Y  + + ++++   + V  +
Sbjct: 271 FFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFI 330

Query: 393 ESLLVQCILDNTIHGRIDQVNQLLE 417
           +  L + I    +H +ID+VN+++E
Sbjct: 331 DQELSRFIAAGRLHCKIDKVNEIVE 355


>gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapiens]
          Length = 1758

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 12   DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKA 71
            D++ Y  E S+D + EP V +  +      + E+  K   S   K+   + E  +W  + 
Sbjct: 1024 DDDAYKTEDSDDIHFEPVVQMPEKV--ELVIGEEGEKVLYSQGVKLFRFDAEVRQWKERG 1081

Query: 72   LKQMIKINFKLTNFPEMMNRYKQLL 96
            L  +  +  ++   P M+ R +Q+L
Sbjct: 1082 LGNLKILKNEVNGKPRMLMRREQVL 1106


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 59/256 (23%), Positives = 107/256 (41%), Gaps = 29/256 (11%)

Query: 32   LENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNR 91
            LE +  + + + ED  ++ +   Q + E + E  E+ ++  +QM   + +L  F E    
Sbjct: 908  LEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQH-EQMNATHTQL--FLEKDEE 964

Query: 92   YKQLLTYIRSAVTRNYSEKSI-----NSILDYISTSKQNSDFLCQM-DLLQEFYETTLEA 145
             K L   I    T+ + E+       + I         N +   +  DL +   E  ++ 
Sbjct: 965  IKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKG 1024

Query: 146  LKDAKND-RLWFKTNTKLGKLY--LEREEYGKLQKILRQ-------LHQSCQTDDGEDDL 195
            +K+ + + +L  + N  L K    L ++E GKL +I++Q       LH    +     D+
Sbjct: 1025 IKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDV 1084

Query: 196  KKGTQLLEIYALEIQMYTAQKN-----NKKLKALYEQSLHIKSAIPHPLIMGVIRECGGK 250
                Q L+ YA+E +   A  N     N  LK  Y + + I +A    LI   +++   K
Sbjct: 1085 VYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIK--LQDENKK 1142

Query: 251  MHLREGEFEKAHTDFF 266
            +  R   FE +  D F
Sbjct: 1143 LSTR---FESSGQDMF 1155


>gi|32698688 citron [Homo sapiens]
          Length = 2027

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 47/219 (21%), Positives = 85/219 (38%), Gaps = 16/219 (7%)

Query: 17   DLEYSEDSNSEPNVDLENQ-YYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQM 75
            DLE   +  +E N +L NQ +Y SK L E     A  +  ++++L  E         +++
Sbjct: 948  DLEEQLNQLTEDNAELNNQNFYLSKQLDE-----ASGANDEIVQLRSEVDH----LRREI 998

Query: 76   IKINFKLTNFPEMMNRYKQLLTYIRS------AVTRNYSEKSINSILDYISTSKQNSDFL 129
             +   +LT+  + M   K   T +        A+     EK             + S F 
Sbjct: 999  TEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFE 1058

Query: 130  CQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTD 189
            C++  LQ   +T  ++   A       +   +L     + E     Q +  Q  ++    
Sbjct: 1059 CRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLS 1118

Query: 190  DGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQS 228
            D  +DL+K   +LE+ A  +Q     +   K + L EQ+
Sbjct: 1119 DKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQA 1157


>gi|27734905 aprataxin and PNKP like factor [Homo sapiens]
          Length = 511

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 1/42 (2%)

Query: 3   DMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKE 44
           D+ D F+ D+EEDY+    EDS+ EP  + E +    + LKE
Sbjct: 463 DLNDSFLDDEEEDYE-PTDEDSDWEPGKEDEEKEDVEELLKE 503


>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
          Length = 1235

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 12/123 (9%)

Query: 328 NDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNI 387
           ND+ +  ++LK N+  + D  F   H E+           KL +   ++ I  +   L  
Sbjct: 349 NDLEKERELLKENYDKLYDSAFSAAHEEQW----------KLKEQQLKVQIAQLETALKS 398

Query: 388 DVADVESLLVQCILDNTIHGRIDQVNQLLELDH--QKRGGARYTALDKWTNQLNSLNQAV 445
           D+ D   +L +   +   + ++ Q N+ L+L +  QK+         K  NQ N +N   
Sbjct: 399 DLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQENDINADE 458

Query: 446 VSK 448
           +S+
Sbjct: 459 LSE 461


>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
          Length = 1315

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 12/123 (9%)

Query: 328 NDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNI 387
           ND+ +  ++LK N+  + D  F   H E+           KL +   ++ I  +   L  
Sbjct: 349 NDLEKERELLKENYDKLYDSAFSAAHEEQW----------KLKEQQLKVQIAQLETALKS 398

Query: 388 DVADVESLLVQCILDNTIHGRIDQVNQLLELDH--QKRGGARYTALDKWTNQLNSLNQAV 445
           D+ D   +L +   +   + ++ Q N+ L+L +  QK+         K  NQ N +N   
Sbjct: 399 DLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQENDINADE 458

Query: 446 VSK 448
           +S+
Sbjct: 459 LSE 461


>gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo
            sapiens]
          Length = 1583

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 9/98 (9%)

Query: 304  QEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRT 363
            Q A     DPE +++T  V A+   D+    ++++     ++D+    EH     RN++ 
Sbjct: 976  QTALSETRDPEEISVT--VKAFMTADLPN--ELIELLEKIVLDNSVFSEH-----RNLQN 1026

Query: 364  QVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCIL 401
             +++  IK      + +IS+  N D  D+ S+ V   L
Sbjct: 1027 LLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSAL 1064


>gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo
            sapiens]
          Length = 1640

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 9/98 (9%)

Query: 304  QEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRT 363
            Q A     DPE +++T  V A+   D+    ++++     ++D+    EH     RN++ 
Sbjct: 976  QTALSETRDPEEISVT--VKAFMTADLPN--ELIELLEKIVLDNSVFSEH-----RNLQN 1026

Query: 364  QVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCIL 401
             +++  IK      + +IS+  N D  D+ S+ V   L
Sbjct: 1027 LLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSAL 1064


>gi|55953112 ret finger protein 2 isoform 2 [Homo sapiens]
          Length = 410

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 11/129 (8%)

Query: 114 SILDYISTSKQNSDFLC--QMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREE 171
           S LD + TSK+ S  L     D ++EF+E     L   KN+ L      KL  +     E
Sbjct: 162 SRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPE 221

Query: 172 YGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHI 231
             KL  IL++   +    +   D+ +    L+      QM   Q+  +K+K + E  L  
Sbjct: 222 INKLNTILQEQRMAFNIAEAFKDVSEPIVFLQ------QM---QEFREKIKVIKETPLPP 272

Query: 232 KSAIPHPLI 240
            +    PL+
Sbjct: 273 SNLPASPLM 281


>gi|47132524 ret finger protein 2 isoform 1 [Homo sapiens]
          Length = 407

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 11/129 (8%)

Query: 114 SILDYISTSKQNSDFLC--QMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREE 171
           S LD + TSK+ S  L     D ++EF+E     L   KN+ L      KL  +     E
Sbjct: 159 SRLDTLETSKRKSLQLLTKDSDKVKEFFEKLQHTLDQKKNEILSDFETMKLAVMQAYDPE 218

Query: 172 YGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHI 231
             KL  IL++   +    +   D+ +    L+      QM   Q+  +K+K + E  L  
Sbjct: 219 INKLNTILQEQRMAFNIAEAFKDVSEPIVFLQ------QM---QEFREKIKVIKETPLPP 269

Query: 232 KSAIPHPLI 240
            +    PL+
Sbjct: 270 SNLPASPLM 278


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,625,109
Number of Sequences: 37866
Number of extensions: 663428
Number of successful extensions: 2516
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 2471
Number of HSP's gapped (non-prelim): 94
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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