Guide to the Human Genome
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Search of human proteins with 217416388

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|217416388 neuralized homolog 1B [Homo sapiens]
         (555 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|217416388 neuralized homolog 1B [Homo sapiens]                    1144   0.0  
gi|223278368 neuralized-like [Homo sapiens]                           427   e-119
gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens]              67   4e-11
gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens]              67   4e-11
gi|18152787 neuralized-like protein 2 [Homo sapiens]                   63   8e-10
gi|53729363 leucine rich repeat and sterile alpha motif containi...    59   2e-08
gi|53729361 leucine rich repeat and sterile alpha motif containi...    59   2e-08
gi|53729359 leucine rich repeat and sterile alpha motif containi...    59   2e-08
gi|62865649 rififylin [Homo sapiens]                                   55   2e-07
gi|17432433 rififylin [Homo sapiens]                                   55   2e-07
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]     55   2e-07
gi|58743365 ring finger protein 157 [Homo sapiens]                     54   5e-07
gi|214010238 mahogunin, ring finger 1 isoform 4 [Homo sapiens]         53   6e-07
gi|214010236 mahogunin, ring finger 1 isoform 3 [Homo sapiens]         53   6e-07
gi|214010234 mahogunin, ring finger 1 isoform 2 [Homo sapiens]         53   6e-07
gi|44917608 mahogunin, ring finger 1 isoform 1 [Homo sapiens]          53   6e-07
gi|147902746 MEX3A protein [Homo sapiens]                              53   8e-07
gi|47716512 mex-3 homolog B [Homo sapiens]                             50   7e-06
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]     49   9e-06
gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]            49   2e-05
gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]            49   2e-05
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa...    48   3e-05
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap...    48   3e-05
gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo sap...    47   4e-05
gi|38788243 myosin regulatory light chain interacting protein [H...    45   2e-04
gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1 ...    44   3e-04
gi|21264330 mindbomb homolog 2 [Homo sapiens]                          44   5e-04
gi|14042925 ring finger protein 26 [Homo sapiens]                      44   5e-04
gi|5729765 cell growth regulator with ring finger domain 1 [Homo...    43   7e-04
gi|45387949 ring finger and SPRY domain containing 1 [Homo sapiens]    43   7e-04

>gi|217416388 neuralized homolog 1B [Homo sapiens]
          Length = 555

 Score = 1144 bits (2959), Expect = 0.0
 Identities = 555/555 (100%), Positives = 555/555 (100%)

Query: 1   MGNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRAT 60
           MGNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRAT
Sbjct: 1   MGNTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRAT 60

Query: 61  RRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACP 120
           RRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACP
Sbjct: 61  RRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACP 120

Query: 121 DLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALI 180
           DLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALI
Sbjct: 121 DLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALI 180

Query: 181 DVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGH 240
           DVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGH
Sbjct: 181 DVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGH 240

Query: 241 LALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVAC 300
           LALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVAC
Sbjct: 241 LALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVAC 300

Query: 301 APRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPD 360
           APRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPD
Sbjct: 301 APRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPD 360

Query: 361 ALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFA 420
           ALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFA
Sbjct: 361 ALLDRKEYWVVARAGPVPSGGDALSFTLRPGGDVLLGINGRPRGRLLCVDTTQALWAFFA 420

Query: 421 VRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSS 480
           VRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSS
Sbjct: 421 VRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSS 480

Query: 481 PLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCP 540
           PLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCP
Sbjct: 481 PLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCP 540

Query: 541 ICRRPIKDVIKIYRP 555
           ICRRPIKDVIKIYRP
Sbjct: 541 ICRRPIKDVIKIYRP 555


>gi|223278368 neuralized-like [Homo sapiens]
          Length = 574

 Score =  427 bits (1099), Expect = e-119
 Identities = 237/526 (45%), Positives = 312/526 (59%), Gaps = 30/526 (5%)

Query: 41  FHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFG 100
           FH   KG  + +D   +   R+ SFCN +TF+ RP+ +YEQVRL++   +  WSGALR G
Sbjct: 65  FHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLG 124

Query: 101 FTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVND 160
           FT+ DPS +    +PKYACPDLV++ G+WAKALPE  A    ++A+W D+ GRVF+ +ND
Sbjct: 125 FTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRIND 184

Query: 161 GEPVLFHCGVAVGGPLWALIDVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHD 220
              +LF  GV    PLWAL+DVYG+T  VQLL+S   + + P  L    F+A   PS   
Sbjct: 185 SAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDS---ELVLPDCLRPRSFTALRRPSL-- 239

Query: 221 AANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADL 280
                  E ++ ++   L  L +  A G   A AA   IP          + PA L+ DL
Sbjct: 240 -----RREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDL 294

Query: 281 RFHATR-GPDVSLSADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALA 339
           RFHA R G  V +  ++ VA        R LVF+ RP+R  E++FV+V R G A PGAL+
Sbjct: 295 RFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALS 354

Query: 340 FGITSCDPGVLRPNELPADPDALLDRKEYWVVARA-GPVPSGGDALSFTLRPGGDVLLGI 398
           FG+T+CDPG LRP +LP  P+AL+DRKE+W V R  GP+ S GD L   +   G++ L  
Sbjct: 355 FGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHS-GDILGLVVNADGELHLSH 413

Query: 399 NGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLG----------TLQSSPATTTPSGSL 448
           NG   G  LCVD +Q LW  F + G +  Q+R+LG          +L  SPA+T  S S 
Sbjct: 414 NGAAAGMQLCVDASQPLWMLFGLHGTIT-QIRILGSTILAERGIPSLPCSPASTPTSPSA 472

Query: 449 SGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFD 508
            GS+    SD   S   S     S+  TAP+SP+S P SPV       G  + ECT+C++
Sbjct: 473 LGSR---LSDPLLSTCSSGPLGSSAGGTAPNSPVSLPESPV---TPGLGQWSDECTICYE 526

Query: 509 GEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYR 554
             VDTVIYTCGHMCLC++CGLRLK+   ACCPICRRPIKD+IK YR
Sbjct: 527 HAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYR 572


>gi|53829370 neuralized homolog 4 isoform 1 [Homo sapiens]
          Length = 1562

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 94/389 (24%), Positives = 152/389 (39%), Gaps = 80/389 (20%)

Query: 26  GPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRN---SFCNGVTFTQRPIRLYEQV 82
           G GP     LG     H +  G+ V L    R A R+     F +G+  ++ P+R     
Sbjct: 29  GSGPGSNGGLGSGGELHPRT-GRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVF 87

Query: 83  RLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDT 142
            +R+      WSG++  G TA DPS++   D P  A      + G W  +    L    +
Sbjct: 88  TVRIDRKVNSWSGSIEIGVTALDPSVL---DFPSSATG---LKGGSWVVSGCSVLRDGRS 141

Query: 143 VLAYWADRHGRVFYSVNDGEPVLFH---------------CGVAVGG---PLWALIDVYG 184
           VL    + +G+    + +G+ V                  CGVA  G    +WA++D+YG
Sbjct: 142 VL----EEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRDCGVAATGLPPRVWAVVDLYG 197

Query: 185 ITDEVQLL------------------------ESAFAD---------TLTPARLSQARFS 211
              ++ +L                        +SA A+          ++PA+     F 
Sbjct: 198 KCTQITVLPPEPGFSPPTPIPTPPLEPLAPTEDSALAEQGTSADEAFMVSPAQARPETFP 257

Query: 212 ACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPAS 271
             L  S +D AN + +E+ +N +++      L      PPA     +           A+
Sbjct: 258 NSL-ESHNDFANMELSEVVSNTILSAYNGGLLNVNLSSPPAGEGLGS--------SGAAT 308

Query: 272 SPALLEAD-LRFHATRGPDVSLSADRKVACAPRP--DGGRTLVFSERPLRPGESLFVEVG 328
           SP L   D L FH   G  + LS + K A   RP  +    +V + RPLR  E   + + 
Sbjct: 309 SPILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRID 368

Query: 329 RPGLAAPGALAFGITSCDPGVLRPNELPA 357
           +      G++  G+T+ +P  L   E PA
Sbjct: 369 KLVDKWSGSIEIGVTTHNPNSL---EYPA 394



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 99/478 (20%), Positives = 166/478 (34%), Gaps = 99/478 (20%)

Query: 29   PERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVA 88
            P   PV G A RFH+   GKNV L+    RA R   + +G+ F+ + +R  E   +++  
Sbjct: 904  PLHSPVAGVAHRFHSTC-GKNVTLEEDGTRAVRAAGYAHGLVFSTKELRAEEVFEVKVEE 962

Query: 89   VRPGWSGALRFGFTAHDPSLM------SAQDIPKYACPDLVTRPGYWAKALP-------- 134
            +   W+G+LR G T   P  M          +P  + P+L T+  +   +          
Sbjct: 963  LDEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPP-SLPELRTKTTWMVSSCEVRRDGQLQ 1021

Query: 135  --------ENLALRDTV-LAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGI 185
                    E L +   V +   AD    +     D  P        +   +WA++D+YG 
Sbjct: 1022 RMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGP----AATGIAKNVWAVLDLYGP 1077

Query: 186  TDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGR 245
               V ++ S         RL ++      PPS       +  E +  +     G   +G 
Sbjct: 1078 VRGVSIVSS--------TRLEES--EGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVG- 1126

Query: 246  APGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPRPD 305
                                         ++   L F    G ++ LS   + A      
Sbjct: 1127 -----------------------------IIPTTLEFLENHGKNILLSNGNRTATRV-AS 1156

Query: 306  GGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDR 365
              + +V   +PL P   + V +         +L  G+ +C P  L     PA   AL  +
Sbjct: 1157 YNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERL---NFPASACAL--K 1211

Query: 366  KEYWVVARAGPVPSG----------------GDALSFTLRPGGDVLLGINGRPRGRLLCV 409
            +  W++   G   +G                G  L   L   G + L +NG  +G +   
Sbjct: 1212 RAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQG-VAVP 1270

Query: 410  DTTQALWAFFAVRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSD-SDMTFSVNQS 466
            D  Q   A       + GQ   +  +   P     SG  +G+Q D + +DM   + +S
Sbjct: 1271 DVPQPCHALV----DLYGQCEQVTIVNPEPGAA--SGKSAGTQGDMEKADMVDGIKES 1322



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 65/251 (25%), Positives = 93/251 (37%), Gaps = 33/251 (13%)

Query: 244 GRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPR 303
           G  PGP P        P G    P    S   L +    H   G  VSLSA  + A   +
Sbjct: 12  GGGPGPGPGGGGG---PSGSGSGP---GSNGGLGSGGELHPRTGRLVSLSACGRTARRQQ 65

Query: 304 P--DGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDA 361
           P  +    LV S  PLR G    V + R   +  G++  G+T+ DP VL   + P+    
Sbjct: 66  PGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVL---DFPSSATG 122

Query: 362 LLDRKEYWVVARAGPVPSG----------------GDALSFTLRPGGDVLLGINGRPRGR 405
           L  +   WVV+    +  G                GD +       G++ L +NGR  G 
Sbjct: 123 L--KGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRDCG- 179

Query: 406 LLCVDTTQALWAFFAVRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQ 465
           +        +WA   + G       L      SP T  P+  L       DS +     Q
Sbjct: 180 VAATGLPPRVWAVVDLYGKCTQITVLPPEPGFSPPTPIPTPPLEPLAPTEDSAL---AEQ 236

Query: 466 SSSASESSLVT 476
            +SA E+ +V+
Sbjct: 237 GTSADEAFMVS 247



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 116/482 (24%), Positives = 177/482 (36%), Gaps = 92/482 (19%)

Query: 9    LPDPSPPA--RLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRN--- 63
            +P+P P    ++  + P  G G       G   RFH Q  G N  +    R A R N   
Sbjct: 692  VPEPLPEGNNQVSPSSPSSGAG-------GSDLRFH-QLHGSNAVITNGGRTALRHNCRS 743

Query: 64   SFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLV 123
             F + +  + R +R  E   + +  +   WSG++  G TA  P  +          P+ +
Sbjct: 744  EFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEF--------PNTM 795

Query: 124  TRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVY 183
            T   Y      +   L  T +             + DG  +  + G          +D  
Sbjct: 796  TDIDY------DTWMLSGTAI-------------MQDGNTMRNNYGCD--------LDAL 828

Query: 184  GITDEVQLLESAFADTLTPARLSQARFSAC--LPPSSHDAANFDNNELENNQVVAKLGHL 241
            G    + ++ +A  D L      Q + +AC  LPP     A  D        +  +   +
Sbjct: 829  GTGARIGMMRTAKGD-LHYFINGQDQGAACSGLPPGKEVYAVVD--------LYGQCVQV 879

Query: 242  ALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSAD--RKVA 299
            ++  A GP     A +       E+  P  SP    A  RFH+T G +V+L  D  R V 
Sbjct: 880  SITNATGPMDNSLATSNTAT---EKSFPLHSPVAGVAH-RFHSTCGKNVTLEEDGTRAVR 935

Query: 300  CAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNE---LP 356
             A    G   LVFS + LR  E   V+V        G+L  G+T+  PG + P      P
Sbjct: 936  AAGYAHG---LVFSTKELRAEEVFEVKVEELDEKWAGSLRLGLTTLAPGEMGPGAGGGGP 992

Query: 357  ADPDAL--LDRKEYWVVARAGPVPSG--------------GDALSFTLRPGGDVLLGI-- 398
              P +L  L  K  W+V+       G              G      +R G D  + I  
Sbjct: 993  GLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILV 1052

Query: 399  NGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLGT-LQSSPATTTPS-GSLSGSQDDSD 456
            +G   G        + +WA   + G V G   +  T L+ S  T  PS  S +GS+ + D
Sbjct: 1053 DGEDMGP-AATGIAKNVWAVLDLYGPVRGVSIVSSTRLEESEGTQPPSPSSDTGSEGEED 1111

Query: 457  SD 458
             +
Sbjct: 1112 DE 1113



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 95/440 (21%), Positives = 155/440 (35%), Gaps = 118/440 (26%)

Query: 3   NTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRR 62
           N + R L   SP   L    P     PER         FH    G+   +    R A R 
Sbjct: 495 NAILRAL---SPEGALRRAAPAAQAEPERL-------LFHPNC-GQKAAITHEGRTALRP 543

Query: 63  NS---FCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYAC 119
           ++   F +GV  + R +R  E  ++R+  +   W+G++  G T H+P+ +          
Sbjct: 544 HATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQ--------L 595

Query: 120 PDLVT--RPGYWAKALPENLALRDTVLAYWADRHGRV-------FYSVNDGEPVLFHCGV 170
           P  +T  R G W       +    T+L  +     R+            DG    F  G+
Sbjct: 596 PSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGM 655

Query: 171 AVGGPLW-------ALIDVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAAN 223
             G   W       A++D+YG     Q  ++   D +  A + +      LP        
Sbjct: 656 TQGPAAWNVPPGVYAVVDLYG-----QAAQATIVDDVEVAPVPEP-----LPEG------ 699

Query: 224 FDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFH 283
                  NNQV           +P  P + A                       +DLRFH
Sbjct: 700 -------NNQV-----------SPSSPSSGAGG---------------------SDLRFH 720

Query: 284 ATRGPDVSLSADRKVACAP--RPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFG 341
              G +  ++   + A     R +    +V S R LR GE   + + +      G++  G
Sbjct: 721 QLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAG 780

Query: 342 ITSCDPGVLRPNELPADPDALLD-RKEYWVVARAGPVPSGG----------DALSFTLRP 390
           +T+     +RP +L   P+ + D   + W+++    +  G           DAL    R 
Sbjct: 781 VTA-----IRPEDLEF-PNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARI 834

Query: 391 G------GDVLLGINGRPRG 404
           G      GD+   ING+ +G
Sbjct: 835 GMMRTAKGDLHYFINGQDQG 854


>gi|53829368 neuralized homolog 4 isoform 2 [Homo sapiens]
          Length = 1560

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 94/389 (24%), Positives = 152/389 (39%), Gaps = 80/389 (20%)

Query: 26  GPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRN---SFCNGVTFTQRPIRLYEQV 82
           G GP     LG     H +  G+ V L    R A R+     F +G+  ++ P+R     
Sbjct: 29  GSGPGSNGGLGSGGELHPRT-GRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVF 87

Query: 83  RLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKALPENLALRDT 142
            +R+      WSG++  G TA DPS++   D P  A      + G W  +    L    +
Sbjct: 88  TVRIDRKVNSWSGSIEIGVTALDPSVL---DFPSSATG---LKGGSWVVSGCSVLRDGRS 141

Query: 143 VLAYWADRHGRVFYSVNDGEPVLFH---------------CGVAVGG---PLWALIDVYG 184
           VL    + +G+    + +G+ V                  CGVA  G    +WA++D+YG
Sbjct: 142 VL----EEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRDCGVAATGLPPRVWAVVDLYG 197

Query: 185 ITDEVQLL------------------------ESAFAD---------TLTPARLSQARFS 211
              ++ +L                        +SA A+          ++PA+     F 
Sbjct: 198 KCTQITVLPPEPGFSPPTPIPTPPLEPLAPTEDSALAEQGTSADEAFMVSPAQARPETFP 257

Query: 212 ACLPPSSHDAANFDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPAS 271
             L  S +D AN + +E+ +N +++      L      PPA     +           A+
Sbjct: 258 NSL-ESHNDFANMELSEVVSNTILSAYNGGLLNVNLSSPPAGEGLGS--------SGAAT 308

Query: 272 SPALLEAD-LRFHATRGPDVSLSADRKVACAPRP--DGGRTLVFSERPLRPGESLFVEVG 328
           SP L   D L FH   G  + LS + K A   RP  +    +V + RPLR  E   + + 
Sbjct: 309 SPILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRID 368

Query: 329 RPGLAAPGALAFGITSCDPGVLRPNELPA 357
           +      G++  G+T+ +P  L   E PA
Sbjct: 369 KLVDKWSGSIEIGVTTHNPNSL---EYPA 394



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 99/478 (20%), Positives = 166/478 (34%), Gaps = 99/478 (20%)

Query: 29   PERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVA 88
            P   PV G A RFH+   GKNV L+    RA R   + +G+ F+ + +R  E   +++  
Sbjct: 902  PLHSPVAGVAHRFHSTC-GKNVTLEEDGTRAVRAAGYAHGLVFSTKELRAEEVFEVKVEE 960

Query: 89   VRPGWSGALRFGFTAHDPSLM------SAQDIPKYACPDLVTRPGYWAKALP-------- 134
            +   W+G+LR G T   P  M          +P  + P+L T+  +   +          
Sbjct: 961  LDEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPP-SLPELRTKTTWMVSSCEVRRDGQLQ 1019

Query: 135  --------ENLALRDTV-LAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVYGI 185
                    E L +   V +   AD    +     D  P        +   +WA++D+YG 
Sbjct: 1020 RMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGP----AATGIAKNVWAVLDLYGP 1075

Query: 186  TDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAANFDNNELENNQVVAKLGHLALGR 245
               V ++ S         RL ++      PPS       +  E +  +     G   +G 
Sbjct: 1076 VRGVSIVSS--------TRLEES--EGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVG- 1124

Query: 246  APGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPRPD 305
                                         ++   L F    G ++ LS   + A      
Sbjct: 1125 -----------------------------IIPTTLEFLENHGKNILLSNGNRTATRV-AS 1154

Query: 306  GGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDR 365
              + +V   +PL P   + V +         +L  G+ +C P  L     PA   AL  +
Sbjct: 1155 YNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERL---NFPASACAL--K 1209

Query: 366  KEYWVVARAGPVPSG----------------GDALSFTLRPGGDVLLGINGRPRGRLLCV 409
            +  W++   G   +G                G  L   L   G + L +NG  +G +   
Sbjct: 1210 RAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQG-VAVP 1268

Query: 410  DTTQALWAFFAVRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSD-SDMTFSVNQS 466
            D  Q   A       + GQ   +  +   P     SG  +G+Q D + +DM   + +S
Sbjct: 1269 DVPQPCHALV----DLYGQCEQVTIVNPEPGAA--SGKSAGTQGDMEKADMVDGIKES 1320



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 65/251 (25%), Positives = 93/251 (37%), Gaps = 33/251 (13%)

Query: 244 GRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPR 303
           G  PGP P        P G    P    S   L +    H   G  VSLSA  + A   +
Sbjct: 12  GGGPGPGPGGGGG---PSGSGSGP---GSNGGLGSGGELHPRTGRLVSLSACGRTARRQQ 65

Query: 304 P--DGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDA 361
           P  +    LV S  PLR G    V + R   +  G++  G+T+ DP VL   + P+    
Sbjct: 66  PGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVL---DFPSSATG 122

Query: 362 LLDRKEYWVVARAGPVPSG----------------GDALSFTLRPGGDVLLGINGRPRGR 405
           L  +   WVV+    +  G                GD +       G++ L +NGR  G 
Sbjct: 123 L--KGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRDCG- 179

Query: 406 LLCVDTTQALWAFFAVRGGVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQ 465
           +        +WA   + G       L      SP T  P+  L       DS +     Q
Sbjct: 180 VAATGLPPRVWAVVDLYGKCTQITVLPPEPGFSPPTPIPTPPLEPLAPTEDSAL---AEQ 236

Query: 466 SSSASESSLVT 476
            +SA E+ +V+
Sbjct: 237 GTSADEAFMVS 247



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 114/482 (23%), Positives = 177/482 (36%), Gaps = 94/482 (19%)

Query: 9    LPDPSPPA--RLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRRN--- 63
            +P+P P    ++  + P  G G       G   RFH Q  G N  +    R A R N   
Sbjct: 692  VPEPLPEGNNQVSPSSPSSGAG-------GSDLRFH-QLHGSNAVITNGGRTALRHNCRS 743

Query: 64   SFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYACPDLV 123
             F + +  + R +R  E   + +  +   WSG++  G TA  P  +          P+ +
Sbjct: 744  EFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEF--------PNTM 795

Query: 124  TRPGYWAKALPENLALRDTVLAYWADRHGRVFYSVNDGEPVLFHCGVAVGGPLWALIDVY 183
            T   Y      +   L  T +             + DG  +  + G          +D  
Sbjct: 796  TDIDY------DTWMLSGTAI-------------MQDGNTMRNNYGCD--------LDAL 828

Query: 184  GITDEVQLLESAFADTLTPARLSQARFSAC--LPPSSHDAANFDNNELENNQVVAKLGHL 241
            G    + ++ +A  D L      Q + +AC  LPP  +   +          +  +   +
Sbjct: 829  GTGARIGMMRTAKGD-LHYFINGQDQGAACSGLPPEVYAVVD----------LYGQCVQV 877

Query: 242  ALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRGPDVSLSAD--RKVA 299
            ++  A GP     A +       E+  P  SP    A  RFH+T G +V+L  D  R V 
Sbjct: 878  SITNATGPMDNSLATSNTAT---EKSFPLHSPVAGVAH-RFHSTCGKNVTLEEDGTRAVR 933

Query: 300  CAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRPNE---LP 356
             A    G   LVFS + LR  E   V+V        G+L  G+T+  PG + P      P
Sbjct: 934  AAGYAHG---LVFSTKELRAEEVFEVKVEELDEKWAGSLRLGLTTLAPGEMGPGAGGGGP 990

Query: 357  ADPDAL--LDRKEYWVVARAGPVPSG--------------GDALSFTLRPGGDVLLGI-- 398
              P +L  L  K  W+V+       G              G      +R G D  + I  
Sbjct: 991  GLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILV 1050

Query: 399  NGRPRGRLLCVDTTQALWAFFAVRGGVAGQLRLLGT-LQSSPATTTPS-GSLSGSQDDSD 456
            +G   G        + +WA   + G V G   +  T L+ S  T  PS  S +GS+ + D
Sbjct: 1051 DGEDMGP-AATGIAKNVWAVLDLYGPVRGVSIVSSTRLEESEGTQPPSPSSDTGSEGEED 1109

Query: 457  SD 458
             +
Sbjct: 1110 DE 1111



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 95/440 (21%), Positives = 155/440 (35%), Gaps = 118/440 (26%)

Query: 3   NTVHRTLPDPSPPARLLATRPCCGPGPERRPVLGEAPRFHAQAKGKNVRLDGHSRRATRR 62
           N + R L   SP   L    P     PER         FH    G+   +    R A R 
Sbjct: 495 NAILRAL---SPEGALRRAAPAAQAEPERL-------LFHPNC-GQKAAITHEGRTALRP 543

Query: 63  NS---FCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRFGFTAHDPSLMSAQDIPKYAC 119
           ++   F +GV  + R +R  E  ++R+  +   W+G++  G T H+P+ +          
Sbjct: 544 HATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQ--------L 595

Query: 120 PDLVT--RPGYWAKALPENLALRDTVLAYWADRHGRV-------FYSVNDGEPVLFHCGV 170
           P  +T  R G W       +    T+L  +     R+            DG    F  G+
Sbjct: 596 PSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGM 655

Query: 171 AVGGPLW-------ALIDVYGITDEVQLLESAFADTLTPARLSQARFSACLPPSSHDAAN 223
             G   W       A++D+YG     Q  ++   D +  A + +      LP        
Sbjct: 656 TQGPAAWNVPPGVYAVVDLYG-----QAAQATIVDDVEVAPVPEP-----LPEG------ 699

Query: 224 FDNNELENNQVVAKLGHLALGRAPGPPPADAAAAAIPCGPRERPRPASSPALLEADLRFH 283
                  NNQV           +P  P + A                       +DLRFH
Sbjct: 700 -------NNQV-----------SPSSPSSGAGG---------------------SDLRFH 720

Query: 284 ATRGPDVSLSADRKVACAP--RPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFG 341
              G +  ++   + A     R +    +V S R LR GE   + + +      G++  G
Sbjct: 721 QLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAG 780

Query: 342 ITSCDPGVLRPNELPADPDALLD-RKEYWVVARAGPVPSGG----------DALSFTLRP 390
           +T+     +RP +L   P+ + D   + W+++    +  G           DAL    R 
Sbjct: 781 VTA-----IRPEDLEF-PNTMTDIDYDTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARI 834

Query: 391 G------GDVLLGINGRPRG 404
           G      GD+   ING+ +G
Sbjct: 835 GMMRTAKGDLHYFINGQDQG 854


>gi|18152787 neuralized-like protein 2 [Homo sapiens]
          Length = 285

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 35/94 (37%), Positives = 51/94 (54%), Gaps = 3/94 (3%)

Query: 40  RFHAQAKGKNVRLDGHSRRATRRNSFCNGVTFTQRPIRLYEQVRLRLVAVRPGWSGALRF 99
           RFH +  G N+R+D    RATR  SF +GV F++ P+   +   + +     GW G LR 
Sbjct: 25  RFH-RVHGANIRVDPSGTRATRVESFAHGVCFSREPLAPGQVFLVEIEEKELGWCGHLRL 83

Query: 100 GFTAHDPSLMSAQDIPKYACPDLVTRPGYWAKAL 133
           G TA DP+  S   +P+++ PDLV     W  A+
Sbjct: 84  GLTALDPA--SLAPVPEFSLPDLVNLGHTWVFAI 115



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 34/109 (31%), Positives = 47/109 (43%), Gaps = 12/109 (11%)

Query: 265 ERPRPASSPALLEADLRFHATRGPDVSLSADRKVACAPRPDG-GRTLVFSERPLRPGESL 323
           ERP P  +        RFH   G ++ +  D     A R +     + FS  PL PG+  
Sbjct: 17  ERPEPPPT--------RFHRVHGANIRV--DPSGTRATRVESFAHGVCFSREPLAPGQVF 66

Query: 324 FVEVGRPGLAAPGALAFGITSCDPGVLRPNELPADPDALLDRKEYWVVA 372
            VE+    L   G L  G+T+ DP  L P    + PD L++    WV A
Sbjct: 67  LVEIEEKELGWCGHLRLGLTALDPASLAPVPEFSLPD-LVNLGHTWVFA 114


>gi|53729363 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 6/80 (7%)

Query: 475 VTAPSSPLSPPVSPVFS-PPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKR 533
           V  P++P  PP S   S PP    ++  EC VC + E   +   CGH+C C  C   L+ 
Sbjct: 646 VVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLR- 704

Query: 534 QARACCPICRRPIKDVIKIY 553
                CP+CR+ I   ++IY
Sbjct: 705 ----TCPLCRQDIAQRLRIY 720


>gi|53729361 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 6/80 (7%)

Query: 475 VTAPSSPLSPPVSPVFS-PPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKR 533
           V  P++P  PP S   S PP    ++  EC VC + E   +   CGH+C C  C   L+ 
Sbjct: 646 VVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLR- 704

Query: 534 QARACCPICRRPIKDVIKIY 553
                CP+CR+ I   ++IY
Sbjct: 705 ----TCPLCRQDIAQRLRIY 720


>gi|53729359 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 6/80 (7%)

Query: 475 VTAPSSPLSPPVSPVFS-PPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKR 533
           V  P++P  PP S   S PP    ++  EC VC + E   +   CGH+C C  C   L+ 
Sbjct: 646 VVTPTAPQEPPESVRPSAPPAELEVQASECVVCLEREAQMIFLNCGHVCCCQQCCQPLR- 704

Query: 534 QARACCPICRRPIKDVIKIY 553
                CP+CR+ I   ++IY
Sbjct: 705 ----TCPLCRQDIAQRLRIY 720


>gi|62865649 rififylin [Homo sapiens]
          Length = 363

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 5/60 (8%)

Query: 495 PAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYR 554
           P+G++   C +C D  +D V+  CGHM  C  CG R+       CPICR+ +   + ++R
Sbjct: 308 PSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNE-----CPICRQYVIRAVHVFR 362


>gi|17432433 rififylin [Homo sapiens]
          Length = 363

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 5/60 (8%)

Query: 495 PAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYR 554
           P+G++   C +C D  +D V+  CGHM  C  CG R+       CPICR+ +   + ++R
Sbjct: 308 PSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNE-----CPICRQYVIRAVHVFR 362


>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
          Length = 651

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 10/101 (9%)

Query: 463 VNQSSSASESSLVTAPSSPLSPPVSPVFS--------PPEPAGIKN--GECTVCFDGEVD 512
           V+    A+ S+  + PSSP +   +P+ S        PP  +       EC VC +GEV 
Sbjct: 550 VSFPGGAAFSTATSLPSSPAAAACAPLDSGASENSRKPPSASSAPALARECVVCAEGEVM 609

Query: 513 TVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIY 553
             +  CGH   C  C +R+  ++   CP CR P    I I+
Sbjct: 610 AALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIHIF 650



 Score = 33.1 bits (74), Expect = 0.68
 Identities = 37/127 (29%), Positives = 44/127 (34%), Gaps = 17/127 (13%)

Query: 242 ALGRAPGP---PPADAAAAAIPCGPRERPRPASSPALLEADLRFHATRG------PDVSL 292
           A G  PGP   PP + A  A P  PR  P P  + A L   L   +  G       D   
Sbjct: 23  AAGEDPGPGPAPPPEGAQEAAP-APRPPPEPDDAAAALRLALDQLSALGLGGAGDTDEEG 81

Query: 293 SADRKVACAPRPDGGRTLVFSERPLRPGESLFVEVGRPGLAAPGALAFGITSCDPGVLRP 352
           +A    A A   DGG     +  P+ P      E G P   AP      +   DP    P
Sbjct: 82  AAGDGAAAAGGADGGA----APEPVPPDGP---EAGAPPTLAPAVAPGSLPLLDPNASPP 134

Query: 353 NELPADP 359
              P  P
Sbjct: 135 PPPPPRP 141


>gi|58743365 ring finger protein 157 [Homo sapiens]
          Length = 679

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 23/53 (43%), Positives = 33/53 (62%), Gaps = 1/53 (1%)

Query: 500 NGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKI 552
           + EC VC     DT+I  C H+CLC++C   L+ QA   CPICR P + +++I
Sbjct: 274 SAECVVCLSDVRDTLILPCRHLCLCNTCADTLRYQANN-CPICRLPFRALLQI 325


>gi|214010238 mahogunin, ring finger 1 isoform 4 [Homo sapiens]
          Length = 531

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 24/53 (45%), Positives = 32/53 (60%), Gaps = 1/53 (1%)

Query: 500 NGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKI 552
           + EC VC     DT+I  C H+CLC SC   L+ QA   CPICR P + +++I
Sbjct: 276 SNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANN-CPICRLPFRALLQI 327


>gi|214010236 mahogunin, ring finger 1 isoform 3 [Homo sapiens]
          Length = 552

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 24/53 (45%), Positives = 32/53 (60%), Gaps = 1/53 (1%)

Query: 500 NGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKI 552
           + EC VC     DT+I  C H+CLC SC   L+ QA   CPICR P + +++I
Sbjct: 275 SNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANN-CPICRLPFRALLQI 326


>gi|214010234 mahogunin, ring finger 1 isoform 2 [Homo sapiens]
          Length = 555

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 24/53 (45%), Positives = 32/53 (60%), Gaps = 1/53 (1%)

Query: 500 NGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKI 552
           + EC VC     DT+I  C H+CLC SC   L+ QA   CPICR P + +++I
Sbjct: 276 SNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANN-CPICRLPFRALLQI 327


>gi|44917608 mahogunin, ring finger 1 isoform 1 [Homo sapiens]
          Length = 576

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 24/53 (45%), Positives = 32/53 (60%), Gaps = 1/53 (1%)

Query: 500 NGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKI 552
           + EC VC     DT+I  C H+CLC SC   L+ QA   CPICR P + +++I
Sbjct: 275 SNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANN-CPICRLPFRALLQI 326


>gi|147902746 MEX3A protein [Homo sapiens]
          Length = 520

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 38/152 (25%), Positives = 61/152 (40%), Gaps = 28/152 (18%)

Query: 424 GVAGQLRLLGTLQSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSS--- 480
           GV  Q    G  ++SP         +G ++ + + + FS   SSS+S +     P     
Sbjct: 374 GVGKQDVYYGVAETSPPLW------AGQENATPTSVLFSSASSSSSSSAKARAGPPGAHR 427

Query: 481 -------------PLSPPVSPV--FSPPEPAGIKNG----ECTVCFDGEVDTVIYTCGHM 521
                        P  PP  P+  FS     G+++     +C VCF+ EV   +  CGH 
Sbjct: 428 SPATSAGPELAGLPRRPPGEPLQGFSKLGGGGLRSPGGGRDCMVCFESEVTAALVPCGHN 487

Query: 522 CLCHSCGLRLKRQARACCPICRRPIKDVIKIY 553
             C  C +R+  +    CP+C       I+I+
Sbjct: 488 LFCMECAVRICERTDPECPVCHITATQAIRIF 519


>gi|47716512 mex-3 homolog B [Homo sapiens]
          Length = 569

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 13/88 (14%)

Query: 466 SSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCH 525
           SSS+S SS  ++ SS L    S              +C+VCF+ EV   +  CGH   C 
Sbjct: 494 SSSSSSSSSSSSSSSGLRRKGSR-------------DCSVCFESEVIAALVPCGHNLFCM 540

Query: 526 SCGLRLKRQARACCPICRRPIKDVIKIY 553
            C  R+  ++   CP+C   +   I+I+
Sbjct: 541 ECANRICEKSEPECPVCHTAVTQAIRIF 568


>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
          Length = 659

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 2/63 (3%)

Query: 491 SPPEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVI 550
           SPPE    +  +C +CF+ EV   +  CGH   C  C  ++  +    CP+C+  +   I
Sbjct: 598 SPPESR--RKHDCVICFENEVIAALVPCGHNLFCMECANKICEKRTPSCPVCQTAVTQAI 655

Query: 551 KIY 553
           +I+
Sbjct: 656 QIH 658


>gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]
          Length = 373

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 5/52 (9%)

Query: 503 CTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYR 554
           C +C D  +D V+  CGHM  C  CG R+       CPICR+ +   + +++
Sbjct: 326 CRICMDAVIDCVLLECGHMVTCTKCGKRMSE-----CPICRQYVVRAVHVFK 372


>gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]
          Length = 372

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 5/52 (9%)

Query: 503 CTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYR 554
           C +C D  +D V+  CGHM  C  CG R+       CPICR+ +   + +++
Sbjct: 325 CRICMDAVIDCVLLECGHMVTCTKCGKRMSE-----CPICRQYVVRAVHVFK 371


>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 5/51 (9%)

Query: 503 CTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIY 553
           C VC D EV  V   CGH+ +C  C   L++     CPICR  IK  ++ +
Sbjct: 557 CKVCMDKEVSIVFIPCGHLVVCKDCAPSLRK-----CPICRSTIKGTVRTF 602


>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 5/51 (9%)

Query: 503 CTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIY 553
           C VC D EV  V   CGH+ +C  C   L++     CPICR  IK  ++ +
Sbjct: 557 CKVCMDKEVSIVFIPCGHLVVCKDCAPSLRK-----CPICRSTIKGTVRTF 602


>gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
           sapiens]
          Length = 618

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 5/51 (9%)

Query: 503 CTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIY 553
           C VC D EV  V   CGH+ +C  C   L++     CPICR  IK  ++ +
Sbjct: 571 CKVCMDKEVSVVFIPCGHLVVCQECAPSLRK-----CPICRGIIKGTVRTF 616


>gi|38788243 myosin regulatory light chain interacting protein [Homo
           sapiens]
          Length = 445

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 5/53 (9%)

Query: 503 CTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP 555
           C VC + E+++    CGH   C SC  +L+      CP+CR  ++ V  +Y P
Sbjct: 387 CMVCCEEEINSTFCPCGHTVCCESCAAQLQ-----SCPVCRSRVEHVQHVYLP 434


>gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1
           [Homo sapiens]
          Length = 352

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 493 PEPAGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKI 552
           PE        C VC       V   CGH+C C  C   L    +  CPICR+ I  VI +
Sbjct: 292 PEDRESLKSACVVCLSSFKSCVFLECGHVCSCTECYRALPEPKK--CPICRQAITRVIPL 349

Query: 553 Y 553
           Y
Sbjct: 350 Y 350


>gi|21264330 mindbomb homolog 2 [Homo sapiens]
          Length = 1013

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 7/51 (13%)

Query: 503  CTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIY 553
            C +C D  +  +++ CGH   C  CG      A + CPICR+PI+D I+I+
Sbjct: 969  CPICIDSHI-RLVFQCGHGA-CAPCG-----SALSACPICRQPIRDRIQIF 1012


>gi|14042925 ring finger protein 26 [Homo sapiens]
          Length = 433

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 2/54 (3%)

Query: 502 ECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQA--RACCPICRRPIKDVIKIY 553
           +C +C D     ++  C H+CLC +C   L R       CP+CRR I   + +Y
Sbjct: 379 KCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRRGILQTLNVY 432


>gi|5729765 cell growth regulator with ring finger domain 1 [Homo
           sapiens]
          Length = 332

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 5/90 (5%)

Query: 459 MTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEPAGIKNGECTVCFDGEVDTVIYTC 518
           M+ + N + S + SS        L   V    S  EP+   + +C VC +G V+ V+  C
Sbjct: 230 MSANNNFTPSNNSSSEEKNTDRSLLEKVGLSESEVEPSEENSKDCVVCQNGTVNWVLLPC 289

Query: 519 GHMCLCHSCGLRLKRQARACCPICRRPIKD 548
            H CLC  C    ++     CP+CR+ +++
Sbjct: 290 RHTCLCDGCVKYFQQ-----CPMCRQFVQE 314


>gi|45387949 ring finger and SPRY domain containing 1 [Homo sapiens]
          Length = 576

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 5/54 (9%)

Query: 498 IKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIK 551
           I+   C++C D   DT +  CGH  LC  C L+L+      CP+CR+ I   I+
Sbjct: 522 IRENCCSLCCDEVADTQLKPCGHSDLCMDCALQLE-----TCPLCRKEIVSRIR 570


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,659,267
Number of Sequences: 37866
Number of extensions: 1493434
Number of successful extensions: 9402
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 8379
Number of HSP's gapped (non-prelim): 1096
length of query: 555
length of database: 18,247,518
effective HSP length: 107
effective length of query: 448
effective length of database: 14,195,856
effective search space: 6359743488
effective search space used: 6359743488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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