Search of human proteins with 21735575

Search of human proteins with 21735575

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21735575 junctophilin 1 [Homo sapiens]
         (661 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21735575 junctophilin 1 [Homo sapiens]                            1364   0.0  
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]                   681   0.0  
gi|21704283 junctophilin 3 [Homo sapiens]                             650   0.0  
gi|225690502 junctophilin 4 [Homo sapiens]                            437   e-122
gi|225690500 junctophilin 4 [Homo sapiens]                            437   e-122
gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]                   252   9e-67
gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]            81   3e-15
gi|157502187 radial spoke head 10 homolog B [Homo sapiens]             81   3e-15
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]              78   2e-14
gi|50355990 MORN repeat containing 3 [Homo sapiens]                    72   2e-12
gi|18254456 testis-specific gene A2 [Homo sapiens]                     71   3e-12
gi|13376267 MORN repeat containing 1 [Homo sapiens]                    67   7e-11
gi|40316935 alsin isoform 1 [Homo sapiens]                             62   1e-09
gi|149999376 MORN repeat containing 4 [Homo sapiens]                   62   1e-09
gi|30520314 MORN repeat containing 4 [Homo sapiens]                    62   1e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     48   3e-05
gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens]       47   6e-05
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    46   1e-04
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...    45   3e-04
gi|224282170 MORN repeat containing 2 [Homo sapiens]                   44   4e-04
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             44   6e-04
gi|30795231 brain abundant, membrane attached signal protein 1 [...    43   0.001
gi|14249338 BUD13 homolog isoform 1 [Homo sapiens]                     43   0.001
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    42   0.002
gi|38679909 testis expressed sequence 2 [Homo sapiens]                 40   0.005
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    40   0.005
gi|55956899 keratin 9 [Homo sapiens]                                   40   0.007
gi|116805330 small conductance calcium-activated potassium chann...    40   0.009
gi|109452587 family with sequence similarity 98, member B isofor...    39   0.015
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     39   0.020

>gi|21735575 junctophilin 1 [Homo sapiens]
          Length = 661

 Score = 1364 bits (3531), Expect = 0.0
 Identities = 661/661 (100%), Positives = 661/661 (100%)

Query: 1   MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY 60
           MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY
Sbjct: 1   MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY 60

Query: 61  QGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV 120
           QGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV
Sbjct: 61  QGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV 120

Query: 121 ETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA 180
           ETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA
Sbjct: 121 ETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA 180

Query: 181 AAADSPAGTRGGFVLNFHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVR 240
           AAADSPAGTRGGFVLNFHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVR
Sbjct: 181 AAADSPAGTRGGFVLNFHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVR 240

Query: 241 SDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGVSERSN 300
           SDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGVSERSN
Sbjct: 241 SDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGVSERSN 300

Query: 301 GMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAI 360
           GMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAI
Sbjct: 301 GMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAI 360

Query: 361 EGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPG 420
           EGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPG
Sbjct: 361 EGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPG 420

Query: 421 PDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSPASSP 480
           PDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSPASSP
Sbjct: 421 PDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSPASSP 480

Query: 481 KPLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPN 540
           KPLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPN
Sbjct: 481 KPLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPN 540

Query: 541 PSNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTKPVA 600
           PSNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTKPVA
Sbjct: 541 PSNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTKPVA 600

Query: 601 KESKAEPKAKKSELAIPKNPASNDSCPALEKEANSGPNSIMIVLVMLLNIGLAILFVHFL 660
           KESKAEPKAKKSELAIPKNPASNDSCPALEKEANSGPNSIMIVLVMLLNIGLAILFVHFL
Sbjct: 601 KESKAEPKAKKSELAIPKNPASNDSCPALEKEANSGPNSIMIVLVMLLNIGLAILFVHFL 660

Query: 661 T 661
           T
Sbjct: 661 T 661


>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
          Length = 696

 Score =  681 bits (1756), Expect = 0.0
 Identities = 363/709 (51%), Positives = 467/709 (65%), Gaps = 61/709 (8%)

Query: 1   MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY 60
           M+GGRFDFDDGG YCGGWE GKAHGHG+CTGPKGQGEYSGSW+ GFEV G YTWPSGNT+
Sbjct: 1   MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF 60

Query: 61  QGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV 120
           +GYW+QGKRHGLG+ETKG+W+Y+GEW+HGFKGRYG+RQS  + A+YEGTW+NGLQDGYG 
Sbjct: 61  EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT 120

Query: 121 ETYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA 180
           ETY DGGTYQGQ+  GMRHGYGVRQSVPYGMA V+RSPLRTSL+SLRSE SNG+V  D+ 
Sbjct: 121 ETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSP 180

Query: 181 A-------AADSPAGTRGGFVLNFHADAELAGK--KKGGLFRRGSLLGSMKLRKSESKSS 231
           A       A  SPA  RGGF L+  A+AE A +  K GGLF+RG+LLG  KLR++ES++S
Sbjct: 181 ASPASDGPALPSPAIPRGGFALSLLANAEAAARAPKGGGLFQRGALLG--KLRRAESRTS 238

Query: 232 ISSKRSSVRSDAAMSRISSSDANSTISFGDV---DCDFCPVEDHVDATTTETYMGEWKND 288
           + S+RS V    +     +SDA ST S G+      +  P E  +DATTTETYMGEWKND
Sbjct: 239 VGSQRSRVSFLKSDLSSGASDAASTASLGEAAEGADEAAPFEADIDATTTETYMGEWKND 298

Query: 289 KRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIR 348
           KR+GFGVSERS+G++YEGEW +N RHGYGCT  PDG +EEGKY++N+LV+  +++++ ++
Sbjct: 299 KRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRRMLQLK 358

Query: 349 HTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAV 408
             K R+KV+ ++EGAQRAAA+AR K EIA SRT+HA+AKA+AA+QAALAA QE +IAR +
Sbjct: 359 SNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTL 418

Query: 409 ARELSPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEK-------PPTPKESPHFYRKGTT 461
           AREL+PDFYQPGP+Y K+R  + +        + P++       P  P+ESP  + + T 
Sbjct: 419 ARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPDRGAGAAGLPQPPRESPQLHERETP 478

Query: 462 PPRSPEASPKHSHSPASSPKP-LKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPT 520
            P     SP  +      P+P + K    S    N +        VT           P+
Sbjct: 479 RPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVT-----------PS 527

Query: 521 KEAGAVVPQSKYSGRHHI------PNPSNG---ELHSQYHGYYVKLNAPQHPPVDVE--- 568
           + AG   P    + R  I      P PS      L+  YH Y V+   P+ PP + +   
Sbjct: 528 EGAGRRSPARPATERMAIEALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQPEP 587

Query: 569 --DGDGSSQSSSA-------LVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSEL----- 614
              G  S+ SS A        +  P   + +P+K   KP+  +++   KA+K+E      
Sbjct: 588 EVSGSESAPSSPATAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKARKTEARGLTK 647

Query: 615 AIPKNPASNDSCPALEK--EANSGPNSIMIVLVMLLNIGLAILFVHFLT 661
           A  K  A  ++  A E   E    PN+I+I +V+LLNIGLAILFVH LT
Sbjct: 648 AGAKKKARKEAALAAEAEVEVEEVPNTILICMVILLNIGLAILFVHLLT 696


>gi|21704283 junctophilin 3 [Homo sapiens]
          Length = 748

 Score =  650 bits (1677), Expect = 0.0
 Identities = 323/493 (65%), Positives = 387/493 (78%), Gaps = 17/493 (3%)

Query: 2   TGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQ 61
           +GGRF+FDDGG+YCGGWE+GKAHGHG+CTGPKGQGEY+GSWSHGFEV+G YTWPSGNTYQ
Sbjct: 3   SGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQ 62

Query: 62  GYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVE 121
           G WAQGKRHG+G+E+KGKW+Y+GEW+HGFKGRYGVR+     A+YEGTWSNGLQDGYG E
Sbjct: 63  GTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTE 122

Query: 122 TYGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAA- 180
           TY DGGTYQGQW GGMR GYGVRQSVPYGMA VIRSPLRTS+ SLRSE +NG+ LH  A 
Sbjct: 123 TYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPDAS 182

Query: 181 -AAADSPAGTRGGFVLNFHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSIS---SKR 236
            A A SPA +RGGFVL  H+D+E+   KK GLFRR SLL  +KLRKSESKSS++   SK+
Sbjct: 183 PAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRR-SLLSGLKLRKSESKSSLASQRSKQ 241

Query: 237 SSVRSDAAMSRISS--SDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFG 294
           SS RS+A MS +SS  SD +STIS G+ + +   +ED +DATTTETY+GEWKNDKR+GFG
Sbjct: 242 SSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFG 301

Query: 295 VSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRHTKTRE 354
           VS+RS+G+KYEGEWA+N+RHGYGC  FPDG+KEEGKYK NILV G RK LIP+R +K RE
Sbjct: 302 VSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIRE 361

Query: 355 KVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSP 414
           KVDRA+E A+RAA +A+ K EIA SRT+H+RAKA+AA  AA  A++E  IAR  A+E SP
Sbjct: 362 KVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSP 421

Query: 415 DFY--QPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTP-PRSPEASPK 471
            F   + G +Y + + Q   D      E +    P  +ESP  YRKGTTP   +P+ SP 
Sbjct: 422 SFQHRENGLEYQRPKRQTSCD----DIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPL 477

Query: 472 HSH--SPASSPKP 482
            S   SPA++P P
Sbjct: 478 QSFPTSPAATPPP 490



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 19/53 (35%), Positives = 34/53 (64%), Gaps = 5/53 (9%)

Query: 607 PKAKKSELAIPKNPASNDSCPALEKEANSGPNSIMIVLVMLLNIGLAILFVHF 659
           P  K   +A+  +  + D     E ++++G   I++V+V+LLNIG+AILF++F
Sbjct: 699 PPQKSLPVALESDEENGD-----ELKSSTGSAPILVVMVILLNIGVAILFINF 746


>gi|225690502 junctophilin 4 [Homo sapiens]
          Length = 628

 Score =  437 bits (1124), Expect = e-122
 Identities = 244/490 (49%), Positives = 303/490 (61%), Gaps = 33/490 (6%)

Query: 3   GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQG 62
           GG+FDFDDGG Y GGWE G+AHG+G+CTGP  QGEYSG W+HGFE +G +T P G++YQG
Sbjct: 4   GGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQG 63

Query: 63  YWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVET 122
           +W QGKR GLGVE K +W YRGEW  G KGR GV +S+ +  RY G W +G QDGYG ET
Sbjct: 64  HWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESV-SGLRYAGLWKDGFQDGYGTET 122

Query: 123 YGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSV-LHDAAA 181
           Y DGGTYQGQW  G RHGYGVRQSVPY  A ++RSP RTSL S  S+       L     
Sbjct: 123 YSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGD 182

Query: 182 AADSPA-GTRGGFVLNFHADAELAGKKK-----GGLFRRGSLLGSMKLRKSESKSSISSK 235
              SPA G+RGGFVL    DA+ A  +K     GG FRR  LL    LR    +SS+ SK
Sbjct: 183 EGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSG--LRAGGRRSSLGSK 240

Query: 236 RSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGV 295
           R S+RS+ +    S+    S  S          +E     + TE Y GEW+ D+R+GFGV
Sbjct: 241 RGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIE----GSATEVYAGEWRADRRSGFGV 296

Query: 296 SERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIR-KQLIPI--RHTKT 352
           S+RSNG++YEGEW  N+RHGYG T  PDGS+EEGKYK N LV G R + L+P+  R  K 
Sbjct: 297 SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKV 356

Query: 353 REKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVAREL 412
           +EKVDRA+EGA+RA + AR + EIA +R A A  KA AA   A  A +   +A+ +A++L
Sbjct: 357 KEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDL 416

Query: 413 SPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKH 472
            P    PG     ++  EG D +           P  ++SP  Y  G TP    E SP+ 
Sbjct: 417 QPMLEAPGRR--PRQDSEGSDTE-----------PLDEDSPGVYENGLTP---SEGSPEL 460

Query: 473 SHSPASSPKP 482
             SPASS +P
Sbjct: 461 PSSPASSRQP 470


>gi|225690500 junctophilin 4 [Homo sapiens]
          Length = 628

 Score =  437 bits (1124), Expect = e-122
 Identities = 244/490 (49%), Positives = 303/490 (61%), Gaps = 33/490 (6%)

Query: 3   GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQG 62
           GG+FDFDDGG Y GGWE G+AHG+G+CTGP  QGEYSG W+HGFE +G +T P G++YQG
Sbjct: 4   GGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWAHGFESLGVFTGPGGHSYQG 63

Query: 63  YWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVET 122
           +W QGKR GLGVE K +W YRGEW  G KGR GV +S+ +  RY G W +G QDGYG ET
Sbjct: 64  HWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESV-SGLRYAGLWKDGFQDGYGTET 122

Query: 123 YGDGGTYQGQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSV-LHDAAA 181
           Y DGGTYQGQW  G RHGYGVRQSVPY  A ++RSP RTSL S  S+       L     
Sbjct: 123 YSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRRTSLDSGHSDPPTPPPPLPLPGD 182

Query: 182 AADSPA-GTRGGFVLNFHADAELAGKKK-----GGLFRRGSLLGSMKLRKSESKSSISSK 235
              SPA G+RGGFVL    DA+ A  +K     GG FRR  LL    LR    +SS+ SK
Sbjct: 183 EGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGFFRRSLLLSG--LRAGGRRSSLGSK 240

Query: 236 RSSVRSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGV 295
           R S+RS+ +    S+    S  S          +E     + TE Y GEW+ D+R+GFGV
Sbjct: 241 RGSLRSEVSSEVGSTGPPGSEASGPPAAAPPALIE----GSATEVYAGEWRADRRSGFGV 296

Query: 296 SERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIR-KQLIPI--RHTKT 352
           S+RSNG++YEGEW  N+RHGYG T  PDGS+EEGKYK N LV G R + L+P+  R  K 
Sbjct: 297 SQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKRNRLVHGGRVRSLLPLALRRGKV 356

Query: 353 REKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVAREL 412
           +EKVDRA+EGA+RA + AR + EIA +R A A  KA AA   A  A +   +A+ +A++L
Sbjct: 357 KEKVDRAVEGARRAVSAARQRQEIAAARAADALLKAVAASSVAEKAVEAARMAKLIAQDL 416

Query: 413 SPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKH 472
            P    PG     ++  EG D +           P  ++SP  Y  G TP    E SP+ 
Sbjct: 417 QPMLEAPGRR--PRQDSEGSDTE-----------PLDEDSPGVYENGLTP---SEGSPEL 460

Query: 473 SHSPASSPKP 482
             SPASS +P
Sbjct: 461 PSSPASSRQP 470


>gi|29893812 junctophilin 2 isoform 2 [Homo sapiens]
          Length = 129

 Score =  252 bits (643), Expect = 9e-67
 Identities = 102/127 (80%), Positives = 117/127 (92%)

Query: 1   MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY 60
           M+GGRFDFDDGG YCGGWE GKAHGHG+CTGPKGQGEYSGSW+ GFEV G YTWPSGNT+
Sbjct: 1   MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTF 60

Query: 61  QGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGV 120
           +GYW+QGKRHGLG+ETKG+W+Y+GEW+HGFKGRYG+RQS  + A+YEGTW+NGLQDGYG 
Sbjct: 61  EGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGT 120

Query: 121 ETYGDGG 127
           ETY DGG
Sbjct: 121 ETYADGG 127



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 40/105 (38%), Positives = 54/105 (51%), Gaps = 9/105 (8%)

Query: 50  GGYTWPSGNTYQGYWAQGKRHGLGVET--KGKWMYRGEWSHGFKGRYGVRQSLCTPA--R 105
           G + +  G  Y G W  GK HG G+ T  KG+  Y G W+ GF+    V      P+   
Sbjct: 4   GRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFE----VAGVYTWPSGNT 59

Query: 106 YEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYG 150
           +EG WS G + G G+ET G    Y+G+W  G +  YG+RQS   G
Sbjct: 60  FEGYWSQGKRHGLGIETKGRW-LYKGEWTHGFKGRYGIRQSSSSG 103



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 1/45 (2%)

Query: 281 YMGEWKNDKRNGFGVSERSN-GMKYEGEWANNKRHGYGCTVFPDG 324
           Y GEW +  +  +G+ + S+ G KYEG W N  + GYG   + DG
Sbjct: 82  YKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADG 126



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 3/38 (7%)

Query: 283 GEWKNDKRNGF---GVSERSNGMKYEGEWANNKRHGYG 317
           GE+      GF   GV    +G  +EG W+  KRHG G
Sbjct: 36  GEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLG 73


>gi|153792461 radial spoke head 10 homolog B2 [Homo sapiens]
          Length = 870

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 47/139 (33%), Positives = 66/139 (47%), Gaps = 5/139 (3%)

Query: 8   FDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGG-YTWPSGNTYQGYWAQ 66
           F  G TY G + EG  HG G      G  +Y G +     +  G YTWP G+ Y+G    
Sbjct: 103 FQGGCTYRGMFSEGLMHGQGTYIWADGL-KYEGDFVKNVPMNHGVYTWPDGSMYEGEVVN 161

Query: 67  GKRHGLGVE--TKGKWMYRGEWSHGFK-GRYGVRQSLCTPARYEGTWSNGLQDGYGVETY 123
           G R+G G+   +     Y G W +G + G+  +  +      YEG W   ++ G+G+  Y
Sbjct: 162 GMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCY 221

Query: 124 GDGGTYQGQWAGGMRHGYG 142
             G  Y+GQW   MRHG G
Sbjct: 222 KSGNIYEGQWEDNMRHGEG 240



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 47/146 (32%), Positives = 62/146 (42%), Gaps = 19/146 (13%)

Query: 13  TYCGGWEEGKAHGHG-ICTGPKGQGEYSGSWSHGFEVVGGYT-WPSGNTYQGYWAQGKRH 70
           +Y G W  GK HG G I    +G   Y G W    +   G   + SGN Y+G W    RH
Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237

Query: 71  GLGVETKGKWM-----YRGEWSHGFKGRYGVR-------QSLCTPAR--YEGTWSNGLQD 116
           G G   + +W+     Y G W  G +  +G         +S   P R  Y G + NG + 
Sbjct: 238 GEG---RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294

Query: 117 GYGVETYGDGGTYQGQWAGGMRHGYG 142
           G G   Y  G  Y G+W    +HG G
Sbjct: 295 GRGKFYYASGAMYDGEWVSNKKHGMG 320



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 74/307 (24%), Positives = 120/307 (39%), Gaps = 60/307 (19%)

Query: 31  GPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGF 90
           G K +G Y G    GF    G     G TY+G +++G  HG G            W+ G 
Sbjct: 88  GEKVRGLYEGE---GFAAFQG-----GCTYRGMFSEGLMHGQGTYI---------WADGL 130

Query: 91  KGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYG 150
           K              YEG +   +   +GV T+ DG  Y+G+   GMR+G+G+ +     
Sbjct: 131 K--------------YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKC---- 172

Query: 151 MATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADSPAGT---RGGFVLNFHADAELAGKK 207
                     T   S      NG   H   +   +  GT    G +V N      +   K
Sbjct: 173 ---------STQPVSYIGHWCNGK-RHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYK 222

Query: 208 KGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFC 267
            G ++  G    +M+  +   +   +++  + R +     I +     T     +     
Sbjct: 223 SGNIYE-GQWEDNMRHGEGRMRWLTTNEEYTGRWERG---IQNGFGTHTWFLKRIRSSQY 278

Query: 268 PVEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKE 327
           P+ +         Y+GE+ N  R+G G    ++G  Y+GEW +NK+HG G   F +G   
Sbjct: 279 PLRNE--------YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVY 330

Query: 328 EGKYKNN 334
           EG + N+
Sbjct: 331 EGAFSND 337



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 275 ATTTETYMGEWKNDKRNGFG--VSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332
           +T   +Y+G W N KR+G G     +     YEG+W  N + G+G   +  G+  EG+++
Sbjct: 173 STQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWE 232

Query: 333 NNI 335
           +N+
Sbjct: 233 DNM 235



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 19/56 (33%), Positives = 30/56 (53%)

Query: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
           TY G +     +G G    ++G+KYEG++  N    +G   +PDGS  EG+  N +
Sbjct: 108 TYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGM 163



 Score = 36.6 bits (83), Expect = 0.076
 Identities = 18/57 (31%), Positives = 26/57 (45%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
           E+Y GE       G G +    G  Y G ++    HG G  ++ DG K EG +  N+
Sbjct: 84  ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNV 140



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 15/37 (40%), Positives = 21/37 (56%)

Query: 106 YEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYG 142
           YEG    GL +G G   +  G TY+G ++ G+ HG G
Sbjct: 86  YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQG 122



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 4   GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSH 44
           G+F +  G  Y G W   K HG G  T   G+  Y G++S+
Sbjct: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR-VYEGAFSN 336


>gi|157502187 radial spoke head 10 homolog B [Homo sapiens]
          Length = 870

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 47/139 (33%), Positives = 66/139 (47%), Gaps = 5/139 (3%)

Query: 8   FDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGG-YTWPSGNTYQGYWAQ 66
           F  G TY G + EG  HG G      G  +Y G +     +  G YTWP G+ Y+G    
Sbjct: 103 FQGGCTYRGMFSEGLMHGQGTYIWADGL-KYEGDFVKNVPMNHGVYTWPDGSMYEGEVVN 161

Query: 67  GKRHGLGVE--TKGKWMYRGEWSHGFK-GRYGVRQSLCTPARYEGTWSNGLQDGYGVETY 123
           G R+G G+   +     Y G W +G + G+  +  +      YEG W   ++ G+G+  Y
Sbjct: 162 GMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCY 221

Query: 124 GDGGTYQGQWAGGMRHGYG 142
             G  Y+GQW   MRHG G
Sbjct: 222 KSGNIYEGQWEDNMRHGEG 240



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 47/146 (32%), Positives = 62/146 (42%), Gaps = 19/146 (13%)

Query: 13  TYCGGWEEGKAHGHG-ICTGPKGQGEYSGSWSHGFEVVGGYT-WPSGNTYQGYWAQGKRH 70
           +Y G W  GK HG G I    +G   Y G W    +   G   + SGN Y+G W    RH
Sbjct: 178 SYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRH 237

Query: 71  GLGVETKGKWM-----YRGEWSHGFKGRYGVR-------QSLCTPAR--YEGTWSNGLQD 116
           G G   + +W+     Y G W  G +  +G         +S   P R  Y G + NG + 
Sbjct: 238 GEG---RMRWLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQYPLRNEYIGEFVNGYRH 294

Query: 117 GYGVETYGDGGTYQGQWAGGMRHGYG 142
           G G   Y  G  Y G+W    +HG G
Sbjct: 295 GRGKFYYASGAMYDGEWVSNKKHGMG 320



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 74/307 (24%), Positives = 120/307 (39%), Gaps = 60/307 (19%)

Query: 31  GPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHGF 90
           G K +G Y G    GF    G     G TY+G +++G  HG G            W+ G 
Sbjct: 88  GEKVRGLYEGE---GFAAFQG-----GCTYRGMFSEGLMHGQGTYI---------WADGL 130

Query: 91  KGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVPYG 150
           K              YEG +   +   +GV T+ DG  Y+G+   GMR+G+G+ +     
Sbjct: 131 K--------------YEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKC---- 172

Query: 151 MATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADSPAGT---RGGFVLNFHADAELAGKK 207
                     T   S      NG   H   +   +  GT    G +V N      +   K
Sbjct: 173 ---------STQPVSYIGHWCNGK-RHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYK 222

Query: 208 KGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDFC 267
            G ++  G    +M+  +   +   +++  + R +     I +     T     +     
Sbjct: 223 SGNIYE-GQWEDNMRHGEGRMRWLTTNEEYTGRWERG---IQNGFGTHTWFLKRIRSSQY 278

Query: 268 PVEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKE 327
           P+ +         Y+GE+ N  R+G G    ++G  Y+GEW +NK+HG G   F +G   
Sbjct: 279 PLRNE--------YIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVY 330

Query: 328 EGKYKNN 334
           EG + N+
Sbjct: 331 EGAFSND 337



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 2/63 (3%)

Query: 275 ATTTETYMGEWKNDKRNGFG--VSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332
           +T   +Y+G W N KR+G G     +     YEG+W  N + G+G   +  G+  EG+++
Sbjct: 173 STQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWE 232

Query: 333 NNI 335
           +N+
Sbjct: 233 DNM 235



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 19/56 (33%), Positives = 30/56 (53%)

Query: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
           TY G +     +G G    ++G+KYEG++  N    +G   +PDGS  EG+  N +
Sbjct: 108 TYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGM 163



 Score = 36.6 bits (83), Expect = 0.076
 Identities = 18/57 (31%), Positives = 26/57 (45%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
           E+Y GE       G G +    G  Y G ++    HG G  ++ DG K EG +  N+
Sbjct: 84  ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNV 140



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 15/37 (40%), Positives = 21/37 (56%)

Query: 106 YEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYG 142
           YEG    GL +G G   +  G TY+G ++ G+ HG G
Sbjct: 86  YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQG 122



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 4   GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSH 44
           G+F +  G  Y G W   K HG G  T   G+  Y G++S+
Sbjct: 297 GKFYYASGAMYDGEWVSNKKHGMGRLTFKNGR-VYEGAFSN 336


>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
          Length = 953

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 48/141 (34%), Positives = 67/141 (47%), Gaps = 10/141 (7%)

Query: 13  TYCGGWEEGKAHGHGICTGPKGQ---GEYSGSWSHGF--EVVGGYTWPSGNTYQGYWAQG 67
           TY G W  G+ HG G    P G+   G +     HGF   ++   +    + Y+ +W +G
Sbjct: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREG 416

Query: 68  KRHGLGV-ETKGKWMYRGEWSHGFKGRYGVRQS---LCTPARYEGTWSNGLQDGYGVETY 123
              G G+ E     +Y+G +  G +  +GV +S      P RY G W  G + GYG+E  
Sbjct: 417 SMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEED 476

Query: 124 GD-GGTYQGQWAGGMRHGYGV 143
           GD G  Y G W  G RHG GV
Sbjct: 477 GDRGERYIGMWQAGQRHGPGV 497



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 44/150 (29%), Positives = 62/150 (41%), Gaps = 10/150 (6%)

Query: 4   GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGE----YSGSWSHGFEVVGGYT-WPSGN 58
           G   + DG  + G + +G  HG GI   P+   +    Y   W  G     G   + +  
Sbjct: 371 GTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWREGSMCGYGICEYSTDE 430

Query: 59  TYQGYWAQGKRHGLGVETKGK-----WMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNG 113
            Y+GY+ +G RHG GV   G      + Y G W  G +  YG+ +      RY G W  G
Sbjct: 431 VYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGIEEDGDRGERYIGMWQAG 490

Query: 114 LQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
            + G GV     G  YQG +      G G+
Sbjct: 491 QRHGPGVMVTQAGVCYQGTFQADKTVGPGI 520



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 38/122 (31%), Positives = 53/122 (43%), Gaps = 12/122 (9%)

Query: 35  QGEYSGSWSHGF-EVVGGYTWPSGNTYQGYWAQGKRHGLGVE-----TKGKW-MYRGEWS 87
           Q  Y G W  G     G   WP G  + G + QG  HG G+      ++ K+  Y+  W 
Sbjct: 355 QATYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDKFDCYKCHWR 414

Query: 88  HGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGT----YQGQWAGGMRHGYGV 143
            G    YG+ +   T   Y+G +  GL+ G+GV   G        Y G W  G R GYG+
Sbjct: 415 EGSMCGYGICE-YSTDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYGI 473

Query: 144 RQ 145
            +
Sbjct: 474 EE 475



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 33/100 (33%), Positives = 48/100 (48%), Gaps = 15/100 (15%)

Query: 59  TYQGYWAQGKRHGLGVETKGKWM----YRGEWSHGFKGRYGVRQSLCTPAR------YEG 108
           TY+G W +G+ HG G     KW     + G +  G +  +G+R  L   A       Y+ 
Sbjct: 357 TYEGEWCRGRPHGKGTL---KWPDGRNHVGNFCQGLEHGFGIR--LLPQASEDKFDCYKC 411

Query: 109 TWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSVP 148
            W  G   GYG+  Y     Y+G +  G+RHG+GV +S P
Sbjct: 412 HWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFGVLESGP 451



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 1/53 (1%)

Query: 281 YMGEWKNDKRNGFGVSERSN-GMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332
           Y G W+  +R+G+G+ E  + G +Y G W   +RHG G  V   G   +G ++
Sbjct: 459 YTGHWERGQRSGYGIEEDGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQ 511



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 22/73 (30%), Positives = 35/73 (47%)

Query: 274 DATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333
           D    E Y+G W+  +R+G GV     G+ Y+G +  +K  G G  +  D S  EG +  
Sbjct: 476 DGDRGERYIGMWQAGQRHGPGVMVTQAGVCYQGTFQADKTVGPGILLSEDDSLYEGTFTR 535

Query: 334 NILVRGIRKQLIP 346
           ++ + G  K   P
Sbjct: 536 DLTLMGKGKVTFP 548



 Score = 36.6 bits (83), Expect = 0.076
 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 6/57 (10%)

Query: 276 TTTETYMGEWKNDKRNGFGVSERS----NGMKYEGEWANNKRHGYGCTVFPDGSKEE 328
           +T E Y G ++   R+GFGV E         +Y G W   +R GYG  +  DG + E
Sbjct: 427 STDEVYKGYFQEGLRHGFGVLESGPQAPQPFRYTGHWERGQRSGYG--IEEDGDRGE 481



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 14/49 (28%), Positives = 25/49 (51%)

Query: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEE 328
           TY GEW   + +G G  +  +G  + G +     HG+G  + P  S+++
Sbjct: 357 TYEGEWCRGRPHGKGTLKWPDGRNHVGNFCQGLEHGFGIRLLPQASEDK 405



 Score = 33.9 bits (76), Expect = 0.49
 Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 304 YEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIP 346
           YEGEW   + HG G   +PDG    G +    L  G   +L+P
Sbjct: 358 YEGEWCRGRPHGKGTLKWPDGRNHVGNFCQG-LEHGFGIRLLP 399



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 12/39 (30%), Positives = 19/39 (48%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYG 317
           + Y   W+     G+G+ E S    Y+G +    RHG+G
Sbjct: 407 DCYKCHWREGSMCGYGICEYSTDEVYKGYFQEGLRHGFG 445


>gi|50355990 MORN repeat containing 3 [Homo sapiens]
          Length = 240

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 44/141 (31%), Positives = 61/141 (43%), Gaps = 9/141 (6%)

Query: 10  DGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGF-EVVGGYTWPSGNT------YQG 62
           +G  Y G WE+   HG G     K    Y G W  G  +  G  + P   T      Y G
Sbjct: 34  NGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPDQQTGKCRRVYSG 93

Query: 63  YWAQGKRHGLGVETKG-KWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVE 121
           +W   K+ G G++  G K  Y G+W    +  +G R        YEG W N   +G G+ 
Sbjct: 94  WWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWG-RMYYSNGDIYEGQWENDKPNGEGML 152

Query: 122 TYGDGGTYQGQWAGGMRHGYG 142
              +G  Y+G W  GM++G G
Sbjct: 153 RLKNGNRYEGCWERGMKNGAG 173



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 19/54 (35%), Positives = 33/54 (61%)

Query: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
           Y G WK DK++G+G+        YEG+W  ++R G+G   + +G   EG+++N+
Sbjct: 91  YSGWWKGDKKSGYGIQFFGPKEYYEGDWCGSQRSGWGRMYYSNGDIYEGQWEND 144



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 10/98 (10%)

Query: 56  SGNTYQGYWAQGKRHGLGVET---KGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSN 112
           S + ++G+  + +R+GL  +     G + Y GEW    K   G +      A YEG W  
Sbjct: 10  SESLWKGWDRKAQRNGLRSQVYAVNGDY-YVGEWEDNVKHGKGTQVWKKKGAIYEGDWKF 68

Query: 113 GLQDGYGVETYGDGGT------YQGQWAGGMRHGYGVR 144
           G +DGYG  +  D  T      Y G W G  + GYG++
Sbjct: 69  GKRDGYGTLSLPDQQTGKCRRVYSGWWKGDKKSGYGIQ 106



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 21/57 (36%), Positives = 34/57 (59%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
           E Y G+W   +R+G+G    SNG  YEG+W N+K +G G     +G++ EG ++  +
Sbjct: 112 EYYEGDWCGSQRSGWGRMYYSNGDIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGM 168



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPD-GSKEEGKYKNNI 335
           + Y G+W+NDK NG G+    NG +YEG W    ++G G     D G   EG + +N+
Sbjct: 135 DIYEGQWENDKPNGEGMLRLKNGNRYEGCWERGMKNGAGRFFHLDHGQLFEGFWVDNM 192



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 269 VEDHVDATTTETYMGEWKNDKRNGFGVSE-RSNGMKYEGEWANNKRHGYGCTVFPD 323
           +   V A   + Y+GEW+++ ++G G    +  G  YEG+W   KR GYG    PD
Sbjct: 26  LRSQVYAVNGDYYVGEWEDNVKHGKGTQVWKKKGAIYEGDWKFGKRDGYGTLSLPD 81



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 4   GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGG--YTWPSGNTYQ 61
           GR  + +G  Y G WE  K +G G+     G   Y G W  G +   G  +    G  ++
Sbjct: 127 GRMYYSNGDIYEGQWENDKPNGEGMLRLKNG-NRYEGCWERGMKNGAGRFFHLDHGQLFE 185

Query: 62  GYW 64
           G+W
Sbjct: 186 GFW 188


>gi|18254456 testis-specific gene A2 [Homo sapiens]
          Length = 309

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 45/118 (38%), Positives = 57/118 (48%), Gaps = 7/118 (5%)

Query: 4   GRFDFDDGGTYCGGWEEGKAHGHGIC---TGPKGQGEYSGSWSHGFEVVGGYTWPSGNTY 60
           GR    +G TY G +E GK HG GI     G +  GEY  +  HG    G + +P G+ Y
Sbjct: 34  GRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHG---QGTFIYPDGSRY 90

Query: 61  QGYWAQGKRHGLGVETK-GKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDG 117
           +G WA   RHG GV        Y GEW    +   G      T ++Y GTW NG Q+G
Sbjct: 91  EGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVNGQQEG 148



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 44/117 (37%), Positives = 59/117 (50%), Gaps = 8/117 (6%)

Query: 31  GPKGQGEYSGSWSHGFEVVGG--YTWPSGNTYQGYWAQGKRHGLGV-ETKGKWMYRGEWS 87
           G    GEY G  +   E  G      P+G+TY+G +  GKRHG G+ + K    Y GE+ 
Sbjct: 13  GENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYV 72

Query: 88  HGFKGRYGVRQSLCTP--ARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYG 142
              K   G   +   P  +RYEG W+N L+ G+GV  Y +  TY G+W    RHG G
Sbjct: 73  RNKKHGQG---TFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQG 126



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 24/57 (42%), Positives = 40/57 (70%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
           +TY G ++  KR+G G+ +  NG +Y GE+  NK+HG G  ++PDGS+ EG++ N++
Sbjct: 42  DTYEGSYEFGKRHGQGIYKFKNGARYIGEYVRNKKHGQGTFIYPDGSRYEGEWANDL 98



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 24/54 (44%), Positives = 31/54 (57%), Gaps = 1/54 (1%)

Query: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPD-GSKEEGKYKN 333
           Y GEW ND R+G GV    N   Y GEW  ++RHG G  ++ + GSK  G + N
Sbjct: 90  YEGEWANDLRHGHGVYYYINNDTYTGEWFAHQRHGQGTYLYAETGSKYVGTWVN 143



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 19/51 (37%), Positives = 32/51 (62%)

Query: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
           Y+GE+  +K++G G     +G +YEGEWAN+ RHG+G   + +     G++
Sbjct: 67  YIGEYVRNKKHGQGTFIYPDGSRYEGEWANDLRHGHGVYYYINNDTYTGEW 117



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 36/134 (26%), Positives = 51/134 (38%), Gaps = 31/134 (23%)

Query: 4   GRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGY 63
           G F + DG  Y G W     HGHG+                       Y + + +TY G 
Sbjct: 80  GTFIYPDGSRYEGEWANDLRHGHGV-----------------------YYYINNDTYTGE 116

Query: 64  WAQGKRHGLG----VETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYG 119
           W   +RHG G     ET  K  Y G W +G   + G  + +    RY+G + N    G G
Sbjct: 117 WFAHQRHGQGTYLYAETGSK--YVGTWVNG--QQEGTAELIHLNHRYQGKFLNKNPVGPG 172

Query: 120 VETYGDGGTYQGQW 133
              +  G    G++
Sbjct: 173 KYVFDVGCEQHGEY 186



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 5/61 (8%)

Query: 279 ETYMGEWKNDK-----RNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333
           E  +GE++  +     R+G G +   NG  YEG +   KRHG G   F +G++  G+Y  
Sbjct: 14  ENDIGEYEGGRNEAGERHGRGRARLPNGDTYEGSYEFGKRHGQGIYKFKNGARYIGEYVR 73

Query: 334 N 334
           N
Sbjct: 74  N 74



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 275 ATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
           A T   Y+G W N ++ G       N  +Y+G++ N    G G  VF  G ++ G+Y+  
Sbjct: 131 AETGSKYVGTWVNGQQEGTAELIHLNH-RYQGKFLNKNPVGPGKYVFDVGCEQHGEYRLT 189

Query: 335 ILVRG 339
            + RG
Sbjct: 190 DMERG 194


>gi|13376267 MORN repeat containing 1 [Homo sapiens]
          Length = 497

 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 50/156 (32%), Positives = 68/156 (43%), Gaps = 30/156 (19%)

Query: 14  YCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGG----YTWPSGNTYQGYWAQGKR 69
           Y G W+ G+ HGHG      G   Y G++  G E+ G     + W SG+T+ G +  G+ 
Sbjct: 39  YEGEWKAGRKHGHGKLLFKDGS-YYEGAFVDG-EITGEGRRHWAW-SGDTFSGQFVLGEP 95

Query: 70  HGLGV-ETKGKWMYRGEWSHGFKG---------------------RYGVRQSLCTPA-RY 106
            G GV E K    Y GE SHG +                      R+G  Q L     +Y
Sbjct: 96  QGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKY 155

Query: 107 EGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYG 142
           +G W    + G+GV    DG TY+GQW   +  G G
Sbjct: 156 DGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLG 191



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 39/128 (30%), Positives = 57/128 (44%), Gaps = 4/128 (3%)

Query: 11  GGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWP-SGNTYQGYWAQGKR 69
           G T+ G +  G+  G+G+     G G Y G  SHG     G+     G  YQG +   KR
Sbjct: 83  GDTFSGQFVLGEPQGYGVMEYKAG-GCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKR 141

Query: 70  HGLG-VETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGT 128
           HG G +  +    Y G+W    +  +GV +     + Y+G W + +  G G   +  G T
Sbjct: 142 HGPGQMLFQNGDKYDGDWVRDRRQGHGVLRC-ADGSTYKGQWHSDVFSGLGSMAHCSGVT 200

Query: 129 YQGQWAGG 136
           Y G W  G
Sbjct: 201 YYGLWING 208



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 35/115 (30%), Positives = 48/115 (41%), Gaps = 10/115 (8%)

Query: 4   GRFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFEVVGGYTWPSGNTY 60
           G  ++  GG Y G    G   GHG      G   QG +  +  HG    G   + +G+ Y
Sbjct: 99  GVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHG---PGQMLFQNGDKY 155

Query: 61  QGYWAQGKRHGLGV-ETKGKWMYRGEW-SHGFKGRYGVRQSLCTPARYEGTWSNG 113
            G W + +R G GV        Y+G+W S  F G   +    C+   Y G W NG
Sbjct: 156 DGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAH--CSGVTYYGLWING 208



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 19/57 (33%), Positives = 35/57 (61%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
           + Y G + ++KR+G G     NG KY+G+W  ++R G+G     DGS  +G++ +++
Sbjct: 130 QVYQGSFHDNKRHGPGQMLFQNGDKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDV 186



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 20/43 (46%), Positives = 27/43 (62%), Gaps = 1/43 (2%)

Query: 290 RNGFGVSERSNGM-KYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
           RNG+GV    N   +YEGEW   ++HG+G  +F DGS  EG +
Sbjct: 24  RNGYGVYVYPNSFFRYEGEWKAGRKHGHGKLLFKDGSYYEGAF 66



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 19/51 (37%), Positives = 28/51 (54%)

Query: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
           Y GE  +  R G G     +G  Y+G + +NKRHG G  +F +G K +G +
Sbjct: 109 YEGEVSHGMREGHGFLVDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDGDW 159



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 20/60 (33%), Positives = 33/60 (55%)

Query: 275 ATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
           A + +T+ G++   +  G+GV E   G  YEGE ++  R G+G  V  DG   +G + +N
Sbjct: 80  AWSGDTFSGQFVLGEPQGYGVMEYKAGGCYEGEVSHGMREGHGFLVDRDGQVYQGSFHDN 139



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 17/55 (30%), Positives = 27/55 (49%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333
           + Y G+W  D+R G GV   ++G  Y+G+W ++   G G      G    G + N
Sbjct: 153 DKYDGDWVRDRRQGHGVLRCADGSTYKGQWHSDVFSGLGSMAHCSGVTYYGLWIN 207



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 70  HGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYG-DGGT 128
           +G+ V     + Y GEW  G K  +G +      + YEG + +G   G G   +   G T
Sbjct: 27  YGVYVYPNSFFRYEGEWKAGRKHGHG-KLLFKDGSYYEGAFVDGEITGEGRRHWAWSGDT 85

Query: 129 YQGQWAGGMRHGYGVRQ 145
           + GQ+  G   GYGV +
Sbjct: 86  FSGQFVLGEPQGYGVME 102


>gi|40316935 alsin isoform 1 [Homo sapiens]
          Length = 1657

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 47/165 (28%), Positives = 63/165 (38%), Gaps = 34/165 (20%)

Query: 13   TYCGGWEEGKAHGHGICTGPKGQ--------------GEYS-------------GSWSHG 45
            TY G W  GK HG G+   P G+              GEY              G W  G
Sbjct: 1048 TYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEG 1107

Query: 46   FEVVGG-YTWPSGNTYQGYWAQGKRHGLGVETKGKW------MYRGEWSHGFKGRYGVRQ 98
                 G Y++ SG  ++G +    RHG G+   GK       M+ G+W    K  YGV  
Sbjct: 1108 KMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFD 1167

Query: 99   SLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
             +    +Y G W + +  G GV     G  Y+G +      G GV
Sbjct: 1168 DITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGV 1212



 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 11/96 (11%)

Query: 59   TYQGYWAQGKRHGLGVETKGKW----MYRGEWSHGFKGRYGV----RQSLCTPARYEGTW 110
            TY G W  GK HG GV    KW    MY G + +G +  YG      +++     Y G W
Sbjct: 1048 TYDGRWLSGKPHGRGVL---KWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHW 1104

Query: 111  SNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQS 146
              G   G GV +Y  G  ++G +   MRHG+G+ +S
Sbjct: 1105 KEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRS 1140



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 23/66 (34%), Positives = 34/66 (51%)

Query: 274  DATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333
            D T  E YMG W++D   G GV     G+ YEG +  NK  G G  +  D +  EG++ +
Sbjct: 1168 DITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSD 1227

Query: 334  NILVRG 339
            +  + G
Sbjct: 1228 DWTLSG 1233



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 104  ARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYG 142
            A Y+G W +G   G GV  + DG  Y G +  G+  GYG
Sbjct: 1047 ATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYG 1085



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 16/37 (43%), Positives = 23/37 (62%)

Query: 281  YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYG 317
            Y+G WK  K  G GV   ++G  +EG + +N RHG+G
Sbjct: 1100 YVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHG 1136



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 275  ATTTETYMGEWKNDKRNGFGV-SERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKN 333
            +++   ++G+W  DK+ G+GV  + + G KY G W ++   G G  V   G   EG +  
Sbjct: 1145 SSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHL 1204

Query: 334  N 334
            N
Sbjct: 1205 N 1205



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 12/32 (37%), Positives = 18/32 (56%)

Query: 304  YEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
            Y+G W + K HG G   +PDG    G ++N +
Sbjct: 1049 YDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGL 1080



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 38/149 (25%), Positives = 56/149 (37%), Gaps = 17/149 (11%)

Query: 4    GRFDFDDGGTYCGGWEEGKAHGHGICTGPK----GQGEYSGSW----SHGFEVVGGYTWP 55
            G + +  G  + G +++   HGHG+    K        + G W      G+ V    T  
Sbjct: 1113 GVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDIT-- 1170

Query: 56   SGNTYQGYWAQGKRHGLG-VETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNG- 113
             G  Y G W      G G V T+    Y G +        GV  S      YEG +S+  
Sbjct: 1171 RGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSE-DDTIYEGEFSDDW 1229

Query: 114  LQDGYGVETYGDG----GTYQGQWAGGMR 138
               G G  T  +G    G + G+W  G++
Sbjct: 1230 TLSGKGTLTMPNGDYIEGYFSGEWGSGIK 1258



 Score = 33.1 bits (74), Expect = 0.84
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 280  TYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYG 317
            TY G W + K +G GV +  +G  Y G + N    GYG
Sbjct: 1048 TYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYG 1085



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 3/35 (8%)

Query: 25   GHGICTGPKG---QGEYSGSWSHGFEVVGGYTWPS 56
            G G  T P G   +G +SG W  G ++ G Y  PS
Sbjct: 1233 GKGTLTMPNGDYIEGYFSGEWGSGIKITGTYFKPS 1267



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 26/121 (21%), Positives = 44/121 (36%), Gaps = 6/121 (4%)

Query: 1    MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGF-EVVGGYTWPSGNT 59
            +  G+        + G W   K  G+G+        +Y G W     +  G      G  
Sbjct: 1138 LRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLY 1197

Query: 60   YQGYWAQGKRHGLGV-ETKGKWMYRGE----WSHGFKGRYGVRQSLCTPARYEGTWSNGL 114
            Y+G +   K  G GV  ++   +Y GE    W+   KG   +         + G W +G+
Sbjct: 1198 YEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPNGDYIEGYFSGEWGSGI 1257

Query: 115  Q 115
            +
Sbjct: 1258 K 1258


>gi|149999376 MORN repeat containing 4 [Homo sapiens]
          Length = 146

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 41/127 (32%), Positives = 59/127 (46%), Gaps = 25/127 (19%)

Query: 1   MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHG-FEVVGGYTWPSGNT 59
           +T G F +  G  Y G W+EG+ HG G      G G Y G + +G F   G  T+  G+ 
Sbjct: 3   LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSR 61

Query: 60  YQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYG 119
           Y+G +AQGK +G+GV  +   M                        +EG + NG  DG+G
Sbjct: 62  YEGEFAQGKFNGVGVFIRYDNM-----------------------TFEGEFKNGRVDGFG 98

Query: 120 VETYGDG 126
           + T+ DG
Sbjct: 99  LLTFPDG 105



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)

Query: 50  GGYTWPSGNTYQGYWAQGKRHGLG-VETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEG 108
           G +T+ SG  Y+G W +G+RHG G +       Y G + +G    +GV  +    +RYEG
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGV-LTFSDGSRYEG 64

Query: 109 TWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
            ++ G  +G GV    D  T++G++  G   G+G+
Sbjct: 65  EFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 41/119 (34%)

Query: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWA-----------------------NNKRHGY 316
           TY+G ++N   NGFGV   S+G +YEGE+A                       N +  G+
Sbjct: 38  TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97

Query: 317 GCTVFPDGS----KEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAIEGAQRAAAMAR 371
           G   FPDGS    + EG ++NN L+R              REK    ++ AQ A+  AR
Sbjct: 98  GLLTFPDGSHGIPRNEGLFENNKLLR--------------REKCSAIVQRAQSASKSAR 142



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 22/53 (41%), Positives = 32/53 (60%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
           E Y GEWK  +R+GFG    ++G  Y G + N   +G+G   F DGS+ EG++
Sbjct: 14  EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEF 66



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 15/37 (40%), Positives = 23/37 (62%)

Query: 299 SNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
           S+G +Y GEW   +RHG+G  +F DG    G ++N +
Sbjct: 11  SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGL 47


>gi|30520314 MORN repeat containing 4 [Homo sapiens]
          Length = 146

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 41/127 (32%), Positives = 59/127 (46%), Gaps = 25/127 (19%)

Query: 1   MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHG-FEVVGGYTWPSGNT 59
           +T G F +  G  Y G W+EG+ HG G      G G Y G + +G F   G  T+  G+ 
Sbjct: 3   LTKGSFTYSSGEEYRGEWKEGRRHGFGQLMFADG-GTYLGHFENGLFNGFGVLTFSDGSR 61

Query: 60  YQGYWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYG 119
           Y+G +AQGK +G+GV  +   M                        +EG + NG  DG+G
Sbjct: 62  YEGEFAQGKFNGVGVFIRYDNM-----------------------TFEGEFKNGRVDGFG 98

Query: 120 VETYGDG 126
           + T+ DG
Sbjct: 99  LLTFPDG 105



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)

Query: 50  GGYTWPSGNTYQGYWAQGKRHGLG-VETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEG 108
           G +T+ SG  Y+G W +G+RHG G +       Y G + +G    +GV  +    +RYEG
Sbjct: 6   GSFTYSSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGV-LTFSDGSRYEG 64

Query: 109 TWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
            ++ G  +G GV    D  T++G++  G   G+G+
Sbjct: 65  EFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGL 99



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 41/119 (34%)

Query: 280 TYMGEWKNDKRNGFGVSERSNGMKYEGEWA-----------------------NNKRHGY 316
           TY+G ++N   NGFGV   S+G +YEGE+A                       N +  G+
Sbjct: 38  TYLGHFENGLFNGFGVLTFSDGSRYEGEFAQGKFNGVGVFIRYDNMTFEGEFKNGRVDGF 97

Query: 317 GCTVFPDGS----KEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAIEGAQRAAAMAR 371
           G   FPDGS    + EG ++NN L+R              REK    ++ AQ A+  AR
Sbjct: 98  GLLTFPDGSHGIPRNEGLFENNKLLR--------------REKCSAIVQRAQSASKSAR 142



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 22/53 (41%), Positives = 32/53 (60%)

Query: 279 ETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
           E Y GEWK  +R+GFG    ++G  Y G + N   +G+G   F DGS+ EG++
Sbjct: 14  EEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEF 66



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 15/37 (40%), Positives = 23/37 (62%)

Query: 299 SNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
           S+G +Y GEW   +RHG+G  +F DG    G ++N +
Sbjct: 11  SSGEEYRGEWKEGRRHGFGQLMFADGGTYLGHFENGL 47


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 68/299 (22%), Positives = 115/299 (38%), Gaps = 41/299 (13%)

Query: 361 EGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPG 420
           EG +        +   +  + A +  K +A   A  A   E + A++ A   SP+     
Sbjct: 495 EGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE-AKSPEKEEAKSPAEVKSPE----- 548

Query: 421 PDYVKQRFQEGVDAKENPEEKVPEKP----PTPKESPHFYRKGTTPPRSPEASPKHSHSP 476
               K +     +AK  PE K PEK     P   +SP    K  +P +    SP  + SP
Sbjct: 549 ----KAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE---KAKSPAKEEAKSPAEAKSP 601

Query: 477 ASSPKPLKKQNPSSGARLNQDKRSVADEQVT-AIVNKPLMSKAPTKEAGAVVPQSKYSGR 535
             +  P+K++  S      + K  V +E  + A V  P  +K+PTKE      ++K   +
Sbjct: 602 EKAKSPVKEEAKSPA----EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEK 657

Query: 536 HHIPNPSNGELHSQYHG---------YYVKLNAPQHPPVDVEDGDGSSQSSSALVH---K 583
               +P   +   +               +  +P+     V++   S + + + V    K
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717

Query: 584 PSANKWSPSKSVTK-------PVAKESKAEPKAKKSELAIPKNPASNDSCPALEKEANS 635
                 SP K   K       PV +E+K+  KAK  E A   +  S ++    ++EA S
Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS 776



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 63/295 (21%), Positives = 110/295 (37%), Gaps = 53/295 (17%)

Query: 351 KTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVAR 410
           K +       +  ++A +  + + +      +  +A+A + ++A    + E   A++  +
Sbjct: 637 KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAE---AKSPEK 693

Query: 411 ELSPDFYQPGPDYVKQRFQEGVDAKE--NPEEKVPEKPPTP-KESPHFYRKGTTPPRSPE 467
             SP         VK+  +    AK     E K PEK  +P KE      K  +P +   
Sbjct: 694 AKSP---------VKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744

Query: 468 ASPKHSHSPASSPKPLKKQNPSSGARLNQDKRSVADE-------QVTAIVNKPLMSKAPT 520
            SP+ + SP  + K L  ++P +     ++ RS AD+        V   V  P  +K+P 
Sbjct: 745 KSPEKAKSPEKA-KTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL 803

Query: 521 KEAGAVVPQSKYSGRHHIPNPSNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSAL 580
           KE  A  P+ +   +  + +P   E   Q     VK+   + PP   E+           
Sbjct: 804 KE-DAKAPEKEIPKKEEVKSPVKEEEKPQE----VKV---KEPPKKAEE----------- 844

Query: 581 VHKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAIPKNPASNDSCPALEKEANS 635
                       K+   P  +E K   K +  +   PK        PA+EK   S
Sbjct: 845 -----------EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES 888



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 65/317 (20%), Positives = 115/317 (36%), Gaps = 29/317 (9%)

Query: 325 SKEEGKYKNNILVRGIRKQLIPIRH-TKTREKVDRAIEGAQRAAAMARTKVEIANSRTAH 383
           S E+ K       +   K   P++   KT EK    ++   ++   A++  +        
Sbjct: 704 SPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS 763

Query: 384 ARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYVKQRFQEGVDAKENPEEKVP 443
             AK  A ++A   A +  + A++  +E         P+  K   +E  DAK  PE+++P
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKE-----EVKSPEKAKSPLKE--DAKA-PEKEIP 815

Query: 444 EKPPTPKESPHFYRKGTTPPRSPEASPKHSHSPASSPKPLKKQNPSSGARLNQDKRSVAD 503
           +K           +      + P    +   +PA+     KK +    A   +  +   +
Sbjct: 816 KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE 875

Query: 504 EQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGELHSQYHGYYVKLNAPQHP 563
           E+    V KP  SK   K+  A         +  +P P   E  ++     VK +A    
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEA-------EDKKKVPTPEK-EAPAKVE---VKEDAKPKE 924

Query: 564 PVDV-----EDGDGSSQSSSALVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAIPK 618
             +V     +D      S  A   + +  K    +   K   ++ K E KAK+ +  + K
Sbjct: 925 KTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSK 984

Query: 619 NPASNDSCPALEKEANS 635
            P    S P  EK   S
Sbjct: 985 EP----SKPKAEKAEKS 997



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 65/321 (20%), Positives = 124/321 (38%), Gaps = 22/321 (6%)

Query: 326 KEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAIEGAQRAAAMARTKVEIANSRT-AHA 384
           K + + K  ++ +  ++ +I    T+  +  +   E  ++ A     K E       A  
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496

Query: 385 RAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYVKQRFQEGVDAKE---NPEEK 441
             +   +  A  AA  E +    V  E         P+  + +    V + E   +P ++
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556

Query: 442 VPEKPPTPKESPHFYRKGTTPPRSPE----ASPKHSHSPASSPKPLKKQNP-SSGARLNQ 496
             + PP  K       K     +SPE     + + + SPA +  P K ++P    A+   
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA 616

Query: 497 DKRSVADEQV--TAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGELHSQYHGYY 554
           + +S   E+    A V  P  +K+PTKE      ++K   +    +P   +   +     
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK----- 671

Query: 555 VKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSEL 614
            +  +P+     V+    S + + + V + +    SP K+   PV +E+K+  KAK    
Sbjct: 672 AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK---SPEKA-KSPVKEEAKSPEKAKSPVK 727

Query: 615 AIPKNPASNDSCPALEKEANS 635
              K P    S   +++EA S
Sbjct: 728 EEAKTPEKAKS--PVKEEAKS 746



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 58/258 (22%), Positives = 101/258 (39%), Gaps = 22/258 (8%)

Query: 370 ARTKVEIANSRTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYVKQRFQ 429
           A++  E+ +   A + AK +A   A   + ++   A++  +E +       P   K   +
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK---AKSPVKEEAKS-----PAEAKSPVK 623

Query: 430 EGVDAKENPEEKVPEKPPTP-KESPHFYRKGTTPPRSPEASPKHSHSP--ASSPKPLKKQ 486
           E  +AK   E K PEK  +P KE      K  +P +    SP+ + SP  A +  P K +
Sbjct: 624 E--EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681

Query: 487 NPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGEL 546
           +P      + +K   A   V      P  +K+P KE      ++K   +     P   + 
Sbjct: 682 SPVKAEAKSPEK---AKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKS 738

Query: 547 HSQYHGYY-VKLNAPQH-PPVDVEDGDGSS----QSSSALVHKPSANKWSPSKSVTKPVA 600
             +       K  +P+    +DV+  +  +    ++ S     P   K    + V  P  
Sbjct: 739 PVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEK 798

Query: 601 KESKAEPKAKKSELAIPK 618
            +S  +  AK  E  IPK
Sbjct: 799 AKSPLKEDAKAPEKEIPK 816



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 68/340 (20%), Positives = 121/340 (35%), Gaps = 34/340 (10%)

Query: 325 SKEEGKYKNNILVRGIRKQLIPIR-HTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAH 383
           S E+ K       +   K   P++   K+ EK    ++   ++   A++ V+      + 
Sbjct: 648 SPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVK--EEAKSP 705

Query: 384 ARAKADAADQAALAARQECDI---ARAVARELSPDFYQP-GPDYVKQRFQEGVDAKENPE 439
            +AK+   ++A    + +  +   A+   +  SP   +   P+  K   +      ++PE
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE 765

Query: 440 EKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSP----ASSPK-----------PLK 484
            K P K      +  F  K  +P +    SP+ + SP    A +P+           P+K
Sbjct: 766 AKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825

Query: 485 KQNPSSGARLNQDKRSVADEQVTAI-----VNKPLMSKAPTKEAGAVVPQSKYSGRHHIP 539
           ++      ++ +  +   +E+  A             +AP KEA     + K       P
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885

Query: 540 NPSNGELHSQYHGYYVKLNAPQ-HPPVDV---EDGDGSSQSSSALVHKPSANKWSPSKSV 595
             S  E   +      K+  P+   P  V   ED     ++  A      A    PSK  
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA 945

Query: 596 TKPVA---KESKAEPKAKKSELAIPKNPASNDSCPALEKE 632
            K  A   K+   E KAKK E        + +    L KE
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 9/77 (11%)

Query: 568 EDGDGSSQSSSALVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAIPKNPASNDS-- 625
           E+ +G  + + +    P+    SP K    PV +E+K+  +AK  E    K+PA   S  
Sbjct: 492 EEAEGGEEETKS---PPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE 548

Query: 626 ---CPALEKEANSGPNS 639
               PA E EA S P +
Sbjct: 549 KAKSPAKE-EAKSPPEA 564



 Score = 30.4 bits (67), Expect = 5.4
 Identities = 37/170 (21%), Positives = 59/170 (34%), Gaps = 16/170 (9%)

Query: 459 GTTPPRSPEASPK----HSHSPASSPKPLKKQNPSSGARL---NQDKRSVADEQVTAIVN 511
           G  P   PE  PK     +H    S + +K    S    +    Q + +   E+VT    
Sbjct: 416 GPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEE 475

Query: 512 KPLMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGELHSQYHGYYVKLNAPQHPPVDVEDGD 571
           K    +   +E G    +++  G     +P   E  S        +      P + +  +
Sbjct: 476 KEAKEEEGKEEEGGEEEEAE-GGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPE 534

Query: 572 GSSQSSSALVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAIPKNPA 621
                S A V  P   K         P  +E+K+ P+AK  E    K+PA
Sbjct: 535 KEEAKSPAEVKSPEKAK--------SPAKEEAKSPPEAKSPEKEEAKSPA 576



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 37/155 (23%), Positives = 64/155 (41%), Gaps = 21/155 (13%)

Query: 351  KTREKVDRAIEGAQRAAAMARTKVEIANSRTA-----HARAKADAADQAALAARQECDIA 405
            K  EK + A+E  + +   A+ K E  + +        A AK +  + A    +++ ++A
Sbjct: 873  KVEEKKEPAVEKPKESKVEAK-KEEAEDKKKVPTPEKEAPAKVEVKEDAK--PKEKTEVA 929

Query: 406  R-----AVARELSPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGT 460
            +     A A+E S       P   K+   E  D KE   +K  EKP T  ++    +  +
Sbjct: 930  KKEPDDAKAKEPSK------PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLS 983

Query: 461  TPPRSPEA--SPKHSHSPASSPKPLKKQNPSSGAR 493
              P  P+A  + K S +     KP +K      A+
Sbjct: 984  KEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAK 1018



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 50/211 (23%), Positives = 83/211 (39%), Gaps = 20/211 (9%)

Query: 207 KKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFGDVDCDF 266
           +KGG     S  GS     S +++S+SS  +S          SS+D+  T+S G   C  
Sbjct: 30  RKGGAGGTRSAAGSSSGFHSWTRTSVSSVSASPSRFRGAGAASSTDSLDTLSNGPEGCMV 89

Query: 267 CPVEDHVDATTTETYMGEWKNDKRNGFGVSER---SNGMKYEGEWANNKRHGYGCTVFPD 323
                 V  + +E    +  ND+  G+    R   ++    EGE A  ++   G +   +
Sbjct: 90  A-----VATSRSEKEQLQALNDRFAGYIDKVRQLEAHNRSLEGEAAALRQQQAGRSAMGE 144

Query: 324 GSKEEGKYKNNILVR--GIRKQL-IPIRH-----TKTREKVDRAIEGAQRAAAMARTKVE 375
             + E +     ++R    R QL +   H        R+++D      + A A AR    
Sbjct: 145 LYEREVREMRGAVLRLGAARGQLRLEQEHLLEDIAHVRQRLDDEARQREEAEAAARALAR 204

Query: 376 IANSRTAHARAKADAADQAALAARQECDIAR 406
            A    A   A+ D   + A A ++EC   R
Sbjct: 205 FAQEAEA---ARVD-LQKKAQALQEECGYLR 231


>gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens]
          Length = 1843

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 56/200 (28%), Positives = 84/200 (42%), Gaps = 35/200 (17%)

Query: 448  TPKESPHFYRKGTTPPRS-PEASPK-----HSHSPASSPKPLKKQNPSSGARLNQDKRSV 501
            TPK  P      T PP+  P+  PK      SH P   PKPL   +PS  + + Q +   
Sbjct: 1311 TPKLDP------TMPPKKKPQLPPKPAHLTQSHPPQRLPKPLPL-SPSFSSEVGQREHQ- 1362

Query: 502  ADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGELHSQYHGYYVKLNAPQ 561
              E+ TAI   P  +K PT      +P ++    H  P+  +G          +   AP+
Sbjct: 1363 RGERDTAI---PQPAKVPTTVDQGHIPLARCPSGHSQPSLQHG----------LSTTAPR 1409

Query: 562  HPPVDVEDGDGSSQSS-----SALVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAI 616
              P   +    ++QSS     +AL H P++ +W P  S  +P+    +  P++  S    
Sbjct: 1410 --PTKNQATGSNAQSSEPPKLNALNHDPTSPQWGPGPSGEQPMEGSHQGAPESPDSLQRN 1467

Query: 617  PKN-PASNDSCPALEKEANS 635
             K      +   ALEKEA S
Sbjct: 1468 QKELQGLLNQVQALEKEAAS 1487


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 60/243 (24%), Positives = 89/243 (36%), Gaps = 26/243 (10%)

Query: 406 RAVARELSPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRS 465
           +A+   L P    PG     Q+       + +P       PP P   P + +   +P  +
Sbjct: 489 QAIQERLIPGQQHPGQQPSFQQLPTCPPLQPHPGLHHQSSPPHPHHQP-WAQLHPSPQNT 547

Query: 466 PEASPKHSHSPASS--PKPLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEA 523
           P+  P H HSP+     KP+      SG      K   +D+ + +I  +P   K   K  
Sbjct: 548 PQKVPVHQHSPSEPFLEKPVPDMTQVSGPNAQLVK---SDDYLPSIEQQPQQKKKKKKNN 604

Query: 524 GAVVPQ-SKYSGRHHIPNP-SNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALV 581
             V    SK  G+   P    N EL+         L+  Q    + +    S        
Sbjct: 605 HIVAEDPSKGFGKDDFPGGVDNQELNRN------SLDGSQE---EKKKKKRSKAKKDPKE 655

Query: 582 HKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAIPKNPASNDS--------CPALEKEA 633
            K    K  P +  T P A +   EPK KK++ A PK  +S  S          AL+K+ 
Sbjct: 656 PKEPKEKKEPKEPKT-PKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKV 714

Query: 634 NSG 636
           N G
Sbjct: 715 NKG 717


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 70/286 (24%), Positives = 100/286 (34%), Gaps = 48/286 (16%)

Query: 40   GSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHG---LGVETKGKWMYRGEWSHGFKGRYGV 96
            G+W+   E   G  W  G T +G WA  K  G    G E +      G W+    G   +
Sbjct: 1270 GTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQAS---GGSWA--LAGNQAI 1324

Query: 97   RQSLCTPARYEGTWSNGLQDG---YGVETYGDGGT------YQGQWAGGMRHGYGVRQSV 147
             +        +G+W  G   G    G E  G   T       +G WAG    G G   SV
Sbjct: 1325 GELWAAGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGA---GAGNMSSV 1381

Query: 148  PYGMATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADSPAGTRGGFVLNFHADAELAGKK 207
             Y    V              +Q+ G     A  +  S  G++  F      +   AG  
Sbjct: 1382 SYWAGVV--------------DQAGGGSW--AGTSDQSGGGSKPRFEDQASGEGSWAG-- 1423

Query: 208  KGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISF-GDVDCDF 266
             GG    GS+LG       E +SS  S   +    +  SR+   D +S  ++ G +D   
Sbjct: 1424 AGGQASGGSMLG------PEDQSSGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSG 1477

Query: 267  CPVEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEG-EWANN 311
               +   +  TTE   G W        G S+     +  G  WAN+
Sbjct: 1478 GGSKPRFENQTTEE--GSWAGAGGQAGGGSKVGPEDQSSGRSWANS 1521


>gi|224282170 MORN repeat containing 2 [Homo sapiens]
          Length = 79

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 19/44 (43%), Positives = 26/44 (59%)

Query: 291 NGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNN 334
           NGFG  E  +G  YEG++ +N  HG G   FP+G+K  G +  N
Sbjct: 2   NGFGRLEHFSGAVYEGQFKDNMFHGLGTYTFPNGAKYTGNFNEN 45



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 6/61 (9%)

Query: 30 TGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWMYRGEWSHG 89
          +G   +G++  +  HG   +G YT+P+G  Y G + + +  G G  T  + +   EWS  
Sbjct: 11 SGAVYEGQFKDNMFHG---LGTYTFPNGAKYTGNFNENRVEGEGEYTDIQGL---EWSGN 64

Query: 90 F 90
          F
Sbjct: 65 F 65



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 13/37 (35%), Positives = 20/37 (54%)

Query: 281 YMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYG 317
           Y G++K++  +G G     NG KY G +  N+  G G
Sbjct: 15  YEGQFKDNMFHGLGTYTFPNGAKYTGNFNENRVEGEG 51


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 40/170 (23%), Positives = 62/170 (36%), Gaps = 33/170 (19%)

Query: 438 PEEKVPEKPPTPKESPHFYRKGTTPPRSPEASP-KHSHSPASSPKPLK------------ 484
           PE K   + P P   P  +    +P +S   S  K  HSP+ SP P K            
Sbjct: 483 PEGKSSSRSPGPH--PRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRA 540

Query: 485 KQNPSSGARLNQDKRSVAD--------------EQVTAIVNKPLMSKAPTKEAGAVVPQS 530
           + + +   R  +  RS +                ++T+   +P+    P+  + +    S
Sbjct: 541 RHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSS 600

Query: 531 KYSGRHHIPNPSNGELHSQY----HGYYVKLNAPQHPPVDVEDGDGSSQS 576
            YS R H  +PS G  H  Y    HG   +  +P   P        SS+S
Sbjct: 601 DYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSES 650



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 47/202 (23%), Positives = 74/202 (36%), Gaps = 23/202 (11%)

Query: 443 PEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSPASSPKPLKKQNPSSGA------RLNQ 496
           P+KP +P  SP    K      +P A  K S SP S+P    +   ++G       R  +
Sbjct: 335 PDKPSSP--SPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRR 392

Query: 497 DKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHI------PNPSNG-ELHSQ 549
            +RS +         +     AP + +   + +++ S           P P  G E    
Sbjct: 393 RRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHG 452

Query: 550 YHGYYVKLNAPQHPPVDVEDGDGS-------SQSSSALVHKPSANKWSPSKSVTKPVAKE 602
            HG   K   P+  P       G+          SS+    P    WS S+S +K  ++ 
Sbjct: 453 GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS 512

Query: 603 SKAEPKAKKSELAIPKNPASND 624
           ++  P +  S    PK P S D
Sbjct: 513 AEKRPHS-PSRSPSPKKPLSRD 533



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 37/178 (20%), Positives = 71/178 (39%), Gaps = 22/178 (12%)

Query: 471 KHSHSPASSPKPLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQS 530
           KH  S ++SP P KK+    G R ++ KR + + + +   + PL  K             
Sbjct: 157 KHWSSSSASPPPKKKKKKKGGHRRSRKKRRL-ESECSCGSSSPLRKK------------K 203

Query: 531 KYSGRHHIPNPSNGELHSQYHG------YYVKLNAPQHPPVDVEDGDGSSQSSSALVHKP 584
           K   +H      +G    + H          + N  +  P     G  S + SS   H P
Sbjct: 204 KSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSP 263

Query: 585 S-ANKWSPSKSVTK--PVAKESKAEPKAKKSELAIPKNPASNDSCPALEKEANSGPNS 639
           S ++ +S S+S ++  P  ++   +  +++S  +   +P+      + ++   SG  S
Sbjct: 264 SLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 21/193 (10%)

Query: 425 KQRFQEGVDAKEN--PEEKVPEKPPTPKESPHFYRKGTTPPRSPE--ASPKHSHSPASSP 480
           K +  EG   +E   P+E  P+    P E+     K   P +  E  A  K     A++ 
Sbjct: 22  KDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEK---PDQDAEGKAEEKEGEKDAAAA 78

Query: 481 K---PLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHH 537
           K   P  +   + GA   + +   A EQ  A        +AP     A  P    +    
Sbjct: 79  KEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAA---- 134

Query: 538 IPNPSNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTK 597
              P+ GE  S+  G   K  AP  P       DG+  S S    KP +++ +PS   T 
Sbjct: 135 ---PAAGEEPSKEEGEPKKTEAPAAPAAQETKSDGAPASDS----KPGSSEAAPSSKETP 187

Query: 598 PVAKESKAEPKAK 610
              +   + PKA+
Sbjct: 188 AATEAPSSTPKAQ 200


>gi|14249338 BUD13 homolog isoform 1 [Homo sapiens]
          Length = 619

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 45/192 (23%), Positives = 73/192 (38%), Gaps = 31/192 (16%)

Query: 447 PTPKESPHFYRKGTTPPR----SPEASP----KHSHSPASSPKPLKKQNPSSGARL---- 494
           P+P   P     G +P R    SP+ SP    +H  S  SSP+ +   +P +  R     
Sbjct: 200 PSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSS 259

Query: 495 --NQDKRSVADE-----QVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGELH 547
              Q +R+  D       VT  + +    KAP + +    P  K SG  H+  P N +  
Sbjct: 260 DTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSK-- 317

Query: 548 SQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTKPVAKESKAEP 607
              + Y   ++ P+        GD     S     K + +  S  +    P  ++S    
Sbjct: 318 ---YEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDS---- 370

Query: 608 KAKKSELAIPKN 619
               S+L+ P+N
Sbjct: 371 ---DSDLSPPRN 379


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 45/186 (24%), Positives = 71/186 (38%), Gaps = 14/186 (7%)

Query: 433 DAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSH--SPASSPKPLKKQNPSS 490
           D++++  E+ PEKPP+    P   +    P  S  +S   S   S + S    + ++ SS
Sbjct: 431 DSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSS 490

Query: 491 GARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVP-----QSKYSGRHHIPNPSNGE 545
            +  N+   + A E      NK  +    TK +    P      ++   RH     S+  
Sbjct: 491 DSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDS 550

Query: 546 LHSQYHGY------YVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTKPV 599
             SQ H             AP+ PP     G  S Q S A   +P   +   +K   KPV
Sbjct: 551 ATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPA-QQEPPQRQTVGTKQPKKPV 609

Query: 600 AKESKA 605
              ++A
Sbjct: 610 KASARA 615



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 39/172 (22%), Positives = 59/172 (34%), Gaps = 27/172 (15%)

Query: 429 QEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSPASSPKPLKKQNP 488
           QE  ++K+ P +   + P  P E+PH  ++      + +  P+        PK   K + 
Sbjct: 554 QEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASA 613

Query: 489 SSGAR-----------LNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRH- 536
            +G+R           L    R    +    +  K     A + E    VP S    +H 
Sbjct: 614 RAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHK 673

Query: 537 -HIPNPS-----------NGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQS 576
             +P PS           N E  +  H   V L   Q PP     G GS  S
Sbjct: 674 SSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPP---HSGSGSRTS 722


>gi|38679909 testis expressed sequence 2 [Homo sapiens]
          Length = 1134

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 49/194 (25%), Positives = 82/194 (42%), Gaps = 21/194 (10%)

Query: 433 DAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSPASSPKPLKK--QNPSS 490
           D      + V  KPP  K + H +++ T P  +   S     SP +SP   +   + P  
Sbjct: 224 DTSRQESDTVSYKPPDSKLNLHLFKQFTQPRNTGGDSKTAPSSPLTSPSDTRSFFKVPEM 283

Query: 491 GARLNQDKRSVADEQVTAIVNKP--LMSKAPTKEAGAVVPQSKYSGRHHIPNPS--NGEL 546
            A++   KR +++     ++ +P  L+SK   +E+G+  P++  S    + N S  NG L
Sbjct: 284 EAKIEDTKRRLSE-----VIYEPFQLLSKIIGEESGSHRPKALSSSASELSNLSSLNGHL 338

Query: 547 HSQYHGYYVKLNAPQHPPVDVE-DGDGSSQSSSALVHKPSANKWSPSKSV-TKPVAKESK 604
            S  + Y +K         D E DG GS  +     H  S  +  P++ +  K     S 
Sbjct: 339 ESN-NNYSIK-----EEECDSEGDGYGSDSNIPRSDHPKSTGE--PTREIELKSSQGSSL 390

Query: 605 AEPKAKKSELAIPK 618
            +   K S L + K
Sbjct: 391 KDLGLKTSSLVLEK 404


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 38/136 (27%), Positives = 52/136 (38%), Gaps = 8/136 (5%)

Query: 439  EEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSPASSP---KPLKKQNPSSGARLN 495
            E+ +P  PP  + S       T P   P      +  PA  P   KP +   P    RL 
Sbjct: 1430 EKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLP 1489

Query: 496  QDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGELHSQYHGYYV 555
               R + + Q  A V      + P  E G  VP    S R  +P        S+ +G  +
Sbjct: 1490 LHVRFLENCQPRAPVTS---GRGPPSEDGPGVPPP--SPRRSVPPSPTSPRASEENGLPL 1544

Query: 556  KLNAPQHPPVDVEDGD 571
             +  P  P VDVEDG+
Sbjct: 1545 LVLPPPAPSVDVEDGE 1560


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 43/135 (31%), Positives = 55/135 (40%), Gaps = 17/135 (12%)

Query: 11  GGTYCGGWEEGKAHGHGICTGPKGQ--GEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGK 68
           GG+Y GG   G   G+G  +G +G   G Y G    G    GGY   SG  + G    G 
Sbjct: 494 GGSYGGG---GSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGH 550

Query: 69  RHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGT 128
             G G    G     G    G+ G  G        +R     S+G   G+G E+   GG+
Sbjct: 551 SGGSGGNYGGGSGSGGGSGGGYGGGSG--------SRGGSGGSHGGGSGFGGES---GGS 599

Query: 129 Y-QGQWAGGMRHGYG 142
           Y  G+ A G   GYG
Sbjct: 600 YGGGEEASGSGGGYG 614



 Score = 29.6 bits (65), Expect = 9.3
 Identities = 20/61 (32%), Positives = 24/61 (39%), Gaps = 4/61 (6%)

Query: 2   TGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQ 61
           +GG      GG Y GG   G   G G   G   +G   GS   G     G+   SG +Y 
Sbjct: 546 SGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGG----SGFGGESGGSYG 601

Query: 62  G 62
           G
Sbjct: 602 G 602


>gi|116805330 small conductance calcium-activated potassium channel
           protein 3 isoform a [Homo sapiens]
          Length = 731

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 43/208 (20%), Positives = 84/208 (40%), Gaps = 25/208 (12%)

Query: 433 DAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHSHSPASSPKPLKKQNPSSGA 492
           D  E+P+   P      ++     ++   PP +P A+P+    P+  P+P + Q      
Sbjct: 14  DLDEDPKCPCPSSGDEQQQQQQQQQQQQPPPPAPPAAPQQPLGPSLQPQPPQLQQQQQQQ 73

Query: 493 RLNQDKRSVAD-EQVTAIVNKP----LMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGELH 547
           +  Q ++      Q+  + ++P    L+  +PT  A    P S  +   H  +    +L+
Sbjct: 74  QQQQQQQPPHPLSQLAQLQSQPVHPGLLHSSPT--AFRAPPSSNSTAILHPSSRQGSQLN 131

Query: 548 SQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSP--------SKSVTKPV 599
              H   +  ++P         G    + +S LVH+  +N ++         S  V KP+
Sbjct: 132 LNDH---LLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPL 188

Query: 600 AKES-------KAEPKAKKSELAIPKNP 620
           ++ S       +AE + +  +L  P NP
Sbjct: 189 SRLSASRRNLIEAETEGQPLQLFSPSNP 216


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 41/134 (30%), Positives = 46/134 (34%), Gaps = 35/134 (26%)

Query: 10  DGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKR 69
           +GG   GGW  G   G G   G  G G   G W  G     G  W  G    G W  G  
Sbjct: 330 EGGGGRGGWGGG---GGGGGRGGGGGGGGRGGWGGG-----GGGWGGGGGGGGGWGGGGG 381

Query: 70  HGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGD--GG 127
            G G        ++G   +G +G YG R                   GYG   YGD  GG
Sbjct: 382 GGRGG-------FQGRGDYGGRGGYGGR------------------GGYGGRGYGDPYGG 416

Query: 128 TYQGQWAGGMRHGY 141
              G   GG   GY
Sbjct: 417 GGGGGGGGGGGGGY 430



 Score = 33.1 bits (74), Expect = 0.84
 Identities = 38/134 (28%), Positives = 46/134 (34%), Gaps = 39/134 (29%)

Query: 3   GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQG 62
           GGR  +  GG   GG   G   G G   G  G G   G W  G    GG+    G    G
Sbjct: 333 GGRGGWGGGG---GGGGRGGGGGGG---GRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGG 386

Query: 63  YWAQGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVET 122
           +             +G+  Y G   +G +G YG R                   GYG + 
Sbjct: 387 F-------------QGRGDYGGRGGYGGRGGYGGR-------------------GYG-DP 413

Query: 123 YGDGGTYQGQWAGG 136
           YG GG   G   GG
Sbjct: 414 YGGGGGGGGGGGGG 427


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 38.5 bits (88), Expect = 0.020
 Identities = 89/435 (20%), Positives = 164/435 (37%), Gaps = 45/435 (10%)

Query: 135 GGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSE---QSNGSVLHDAAAA--ADSPAGT 189
           G  R GYG R+S         R+  R  + +L S    Q     +  A     AD+  G 
Sbjct: 80  GSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGR 139

Query: 190 RGGFVLNF--HADAELAGKKKGGLFRRGSLL-------GSMKLRK-SESKSSISSKRSSV 239
           +   V+ F  ++D + A +K  G    G  +       GS + R  S S+S   S+  S 
Sbjct: 140 KNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSR 199

Query: 240 RSDAAMSRISSSDANSTISFGDVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGVSERS 299
            S  + SR  SS ++ + S                + +        ++  R+    S++ 
Sbjct: 200 HSRKSRSRSGSSKSSHSKS-----------RSRSRSGSRSRSKSRSRSQSRSR---SKKE 245

Query: 300 NGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNILVRGIRKQLIPIRH---TKTREKV 356
                  E + ++ H  G +      + E K +NN  V G  K   P RH   +K+R + 
Sbjct: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV-GKPKSRSPSRHKSKSKSRSRS 304

Query: 357 DRAIEGAQRAAAMARTKVEIANSRTAHARAKADAADQAALAARQECDI---ARAVARELS 413
                  ++  +++R + +  + R + +R+++    ++   +R +       R  +RE S
Sbjct: 305 QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES 364

Query: 414 PDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPKESPHFYRKGTTPPRSPEASPKHS 473
               +      + R +      +    K  +K  T +       +  +P RS     +H+
Sbjct: 365 RSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRS------QSRSPSRSVSKEREHA 418

Query: 474 HSPASSPKPLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYS 533
            S +S  +    +  S  A  NQ+ RS +     +  N P  S++ +K A     +SK  
Sbjct: 419 KSESSQREG---RGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSR 475

Query: 534 GRHHIPNPSNGELHS 548
            R    +PS     S
Sbjct: 476 SRSASRSPSRSRSRS 490


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,889,803
Number of Sequences: 37866
Number of extensions: 1556291
Number of successful extensions: 8417
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 360
Number of HSP's that attempted gapping in prelim test: 6783
Number of HSP's gapped (non-prelim): 1446
length of query: 661
length of database: 18,247,518
effective HSP length: 109
effective length of query: 552
effective length of database: 14,120,124
effective search space: 7794308448
effective search space used: 7794308448
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.